The European & Developing Countries Clinical Trials Partnership (EDCTP)

In 2016, EDCTP will launch nine calls for proposals to support clinical research and related activities. Deadline: Several.

The EDCTP aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against:

  • HIV/AIDS
  • tuberculosis
  • malaria
  • other poverty-related and neglected infectious diseases in sub-Saharan Africa.

Who can apply?

Applications must be sent by consortia comprised of:

  • a minimum of three independent legal entities.
  • two of the legal entities must be established in two different European Participating States of the EDCTP Association
  • one of the legal entities must be established in a sub-Saharan African country.
  • all three legal entities shall be independent of each other.

Vaccines for poverty-related diseases (PRDs)

The purpose of this call is to support large-scale collaborative projects which include one or more clinical trials (phase I to IV) aiming to accelerate the clinical development of new vaccines (preventive or therapeutic) against one of the PRDs. Applications must include at least one clinical trial which will be carried out in sub-Saharan Africa to test the safety, immunogenicity and/or efficacy of the vaccine(s).

Deadlines (Two stages)

  • Stage 1 deadline: 13 October 2016
  • Stage 2 deadline: 17 March 2017

What will be funded: Large-scale collaborative funding of maximum funding €15 million.

More information and link to the application form

Research and clinical management of patients in PRD epidemics in sub-Saharan Africa

This call for proposals aims to support the establishment of a multidisciplinary consortium able to provide accelerated evidence for the optimal clinical management of patients and for guiding the public health response to any severe infectious outbreak caused by pathogens within the scope of the EDCTP programme with pandemic potential or that may cause significant damage to health and socio-economics in Africa (including antimicrobial-resistant pathogens).

Deadlines (Two stages)

  • Stage 1 (letter of intent) deadline: 29 September 2016
  • Stage 2 (full proposal) deadline: 2 March 2017

What will be funded: Establishment of a multidisciplinary consortium with maximum funding of €10 million.

More information and link to the application form

Strategic actions supporting large-scale clinical trials

The purpose of this call for proposals is to support distinct strategic actions (clinical research activities) which are part of a large-scale clinical trial that has the potential to achieve rapid advances in the clinical development of new or improved medical interventions against PRDs.

Deadlines (Two stages)

  • Stage 1 (letter of intent) deadline: 13 October 2016
  • Stage 2 (full proposal) deadline: 16 March 2017

What will be funded: Distinct strategic actions (clinical research activities) which are part of a large-scale clinical trial with maximum funding of €15 million.

More information and link to the application form

Clinical trials and operational research studies to optimise the use of products for poverty-related diseases in mothers, newborns, children and/or adolescents

This call aims to support actions on preventive and therapeutic clinical interventions of post-registration products, as well as related behavioural studies, aimed at optimising use of new or improved products or combination of products for mothers, newborns,

Two stage proposal.

  • Stage 1 (letter of intent) deadline: 6 September 2016
  • Stage 2 (full proposal) deadline: 2 March 2017

Activities may include: studies on product (drugs, vaccines, microbicides and diagnostics) development, delivery, uptake and adherence; and strategies for equitable and full-scale access to diagnostics, prevention and treatment interventions. Maximum funding of €3 million.

More information and link to the application form

Strategic actions supporting health systems/services optimisation research capacities in cooperation with development assistance initiatives

The purpose of this call for proposals is to support distinct strategic actions to strengthen the capacity of health systems to effectively deliver new products and to monitor their post-market safety. This will be achieved through effective cooperation with relevant European Union initiatives including development assistance.

Two stage proposal.

  • Stage 1 (letter of intent) deadline: 29 September 2016
  • Stage 2 (full proposal) deadline: 2 March 2017

The projects should lead to better planning for the introduction of new medical interventions for PRDs; improved delivery; and, better understanding of the safety profile of and reporting mechanisms for products introduced in sub-Saharan Africa. Maximum funding of €3 million.

More information and link to the application form

Ethics and regulatory capacities

The purpose of this call for proposals is to provide funding to actions that aim to support sub-Saharan African countries to establish and develop robust national medicines regulatory systems and capacities for ethical review of clinical research and use of medicinal products and technologies for use in humans. This scheme targets both National Ethics Committees (NECs) and National Regulatory Authorities (NRAs).

One stage proposal. Deadline: 22 November 2016

Maximum funding of €300.000.

More information and link to the application form

EDCTP-WHO/TDR Clinical Research and Development Fellowships

This call for proposal is a joint initiative with WHO-TDR to support researchers and key members of clinical trial research teams from low- and middle-income countries (LMICs) to acquire specific skills in clinical research and development through placements in pharmaceutical companies, PDPs and academic affiliated research institutions.

Two stage proposal.

  • Stage 1 (letter of intent) deadline: 2 February 2017
  • Stage 2 (Training plan – EDCTP only) deadline: September 2017

The scheme targets junior to mid-career researchers or clinical staff (clinicians, pharmacists, medical statisticians, data managers, other health researchers) who are employed by a legal entity in LMICs where they are currently working on activities in the scope of the EDCTP programme and the WHO/TDR CDF programme.

Placements are for a minimum period of 12 months up to a maximum period of 18 months, following which there will be a re-integration period of 6 months (subject to the approval of a final re-integration plan).

More information and link to the application form

Senior Fellowships

This call for proposals aims to support capacity development of potential African research leaders using the train-the-trainer model and to mentor junior researchers with emphasis on hands-on research training linked to clinical trials activities conducted in sub-Saharan Africa.

One stage proposal. Deadline: 1 February 2017

The objectives of the scheme are:

  1. To support senior researchers to advance themselves as recognised research leaders in product development through clinical trials and related activities
  2. To equip senior researchers with the necessary skills and experience to train and mentor junior researchers at host institutions in sub-Saharan Africa.

Maximum funding: € 500.000

More information and link to the application form

Career Development Fellowships

This call for proposals aims to provide funding to actions that aim to support junior to mid-career researchers ("fellows") to train and develop their clinical research skills.

One stage proposal. Deadline: 28 February 2017

What will be funded: The objectives are:

  1. To promote career development and retention of postdoctoral researchers and postgraduate medical researchers in the research field and in sub-Saharan Africa;
  2. To equip the fellows with the ability to establish themselves as independent researchers and with the skills to initiate and manage their own research and team at host organisations in sub-Saharan Africa.

Maximum funding: € 150.000

More information and link to the application form

Published Aug. 11, 2016 2:33 PM - Last modified Aug. 12, 2016 10:38 AM