Mette Kalager

Associate Professor
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Visiting address Gaustad Hospital Building 20 Sognsvannsveien 21 0372 Oslo
Postal address University of Oslo Clinical Effectiveness Research Group Sognsvannsveien 21 0372 Oslo
Tags: Nordic, USA

Publications

  • Adami, Hans Olov; Csermely, Peter; Veres, DV; Emilsson, Louise; Løberg, Magnus; Bretthauer, Michael & Kalager, Mette (2017). Are rapidly growing cancers more lethal?. European Journal of Cancer.  ISSN 0959-8049.  72, s 210- 214 . doi: 10.1016/j.ejca.2016.11.011
  • Emilsson, Louise; Holme, Øyvind; Bretthauer, Michael; Cook, Nancy R.; Buring, Julie E.; Løberg, Magnus; Adami, Hans Olov; Sesso, Howard D.; Gaziano, Mike & Kalager, Mette (2017). Systematic review with meta-analysis: the comparative effectiveness of aspirin vs. screening for colorectal cancer prevention. Alimentary Pharmacology and Therapeutics.  ISSN 0269-2813.  45(2), s 193- 204 . doi: 10.1111/apt.13857
  • Garborg, Kjetil Kjeldstad; Wiig, Håvard; Hasund, Audun; Matre, Jon; Holme, Øyvind; Noraberg, Geir; Løberg, Magnus; Kalager, Mette; Adami, Hans Olov & Bretthauer, Michael (2017). Gradual stiffness versus magnetic imaging-guided variable stiffness colonoscopes: A randomized noninferiority trial. United European Gastroenterology journal.  ISSN 2050-6406.  5(1), s 128- 133 . doi: 10.1177/2050640616639162
  • Holme, Øyvind; Schoen, Robert E.; Senore, Carlo; Segnan, Nereo; Hoff, Geir; Løberg, Magnus; Bretthauer, Michael; Adami, Hans Olov & Kalager, Mette (2017). Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials. BMJ (Clinical Research Edition).  ISSN 0959-8138.  s 1- 8 . doi: 10.1136/bmj.i6673
  • Jørgensen, Karsten Juhl; Gøtzsche, Peter C; Kalager, Mette & Zahl, Per Henrik (2017). Breast cancer screening in Denmark: A cohort study of tumor size and overdiagnosis. Annals of Internal Medicine.  ISSN 0003-4819.  166(5), s 313- 323 . doi: 10.7326/M16-0270
  • Jørgensen, Karsten Juhl; Kalager, Mette; Barratt, Alexandra; Baines, Cornelia; Zahl, Per Henrik; Brodersen, John & Harris, Russell P (2017). Overview of guidelines on breast screening: Why recommendations differ and what to do about it. Breast.  ISSN 0960-9776.  31, s 261- 269 . doi: 10.1016/j.breast.2016.08.002
  • Adami, Hans Olov; Bretthauer, Michael; Emilsson, Louise; Hernan, Miguel A.; Kalager, Mette; Ludvigsson, Jonas F. & Ekbom, Anders (2016). The continuing uncertainty about cancer risk in inflammatory bowel disease. Gut.  ISSN 0017-5749.  65(6), s 889- 893 . doi: 10.1136/gutjnl-2015-311003
  • Berstad, Paula Marianna; Botteri, Edoardo; Larsen, Inger Kristin; Løberg, Magnus; Kalager, Mette; Holme, Øyvind; Bretthauer, Michael & Hoff, Geir (2016). Lifestyle changes at middle age and mortality: A population-based prospective cohort study. Journal of Epidemiology and Community Health.  ISSN 0143-005X.  71(1), s 59- 66 . doi: 10.1136/jech-2015-206760
  • Bretthauer, Michael; Kalager, Mette & Adami, Hans Olov (2016). Do's and don'ts in evaluation of endoscopic screening for gastrointestinal cancers. Endoscopy.  ISSN 0013-726X.  48(1), s 75- 80 . doi: 10.1055/s-0034-1393094
  • Bretthauer, Michael; Kaminski, Michal Filip; Løberg, Magnus; Zauber, Ann G.; Regula, Jaroslaw; Kuipers, Ernst J.; Hernan, Miguel A.; McFadden, Elenaor; Sunde, Annike; Kalager, Mette; Dekker, Evelien; Lansdorp-Vogelaar, Iris; Garborg, Kjetil Kjeldstad; Rupinski, Maciej; Spaander, Manon C.W.; Bugajski, Marek; Høie, Ole Ingebreth; Stefansson, Tryggvi; Hoff, Geir & Adami, Hans Olov (2016). Population-Based colonoscopy screening for colorectal cancer : A randomized clinical trial. JAMA Internal Medicine.  ISSN 2168-6106.  176(7), s 894- 902 . doi: 10.1001/jamainternmed.2016.0960
  • Gjøstein, Dagrun Kyte; Huitfeldt, Anders; Løberg, Magnus; Adami, Hans Olov; Garborg, Kjetil Kjeldstad; Kalager, Mette & Bretthauer, Michael (2016). Incentiver og deltagelse i en medisinsk spørreundersøkelse. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  136(12-13), s 1082- 1087 . doi: 10.4045/tidsskr.15.1096
  • Holme, Øyvind; de Lange, Thomas; Stallemo, Asbjørn; Wiig, Håvard; Hasund, Audun; Dvergsnes, Katrine; Garborg, Kjetil Kjeldstad; Ystrøm, Carl Magnus; Løberg, Magnus; Hoff, Geir; Bretthauer, Michael & Kalager, Mette (2016). Routine vs. on-demand analgesia in colonoscopy: a randomized clinical trial. Endoscopy.  ISSN 0013-726X.  48(09), s 823- 828 . doi: 10.1055/s-0042-108433
  • Huitfeldt, Anders; Hernan, Miguel A.; Kalager, Mette & robins, james (2016). Comparative Effectiveness Research Using Observational Data: Active Comparators to Emulate Target Trials with Inactive Comparators.. eGEMs.  ISSN 2327-9214. . doi: 10.13063/2327-9214.1234
  • Jover, Rodrigo; Bretthauer, Michael; Dekker, Evelien; Holme, Øyvind; Kaminski, Michal Filip; Løberg, Magnus; Zauber, AG; Hernan, Miguel A.; Lansdorp-Vogelaar, I; Sunde, Annike; McFadden, Elenaor; Castells, A; Regula, Jaroslaw; Quintero, Enrique; Pellise, Maria; Senore, Carlo; Kalager, Mette; Dinis-Ribeiro, Mario; Emilsson, Louise; Ransohoff, David F.; Hoff, Geir & Adami, Hans Olov (2016). Rationale and design of the European Polyp Surveillance (EPoS) trials. Endoscopy.  ISSN 0013-726X.  48(6), s 571- 578 . doi: 10.1055/s-0042-104116
  • Berstad, Paula Marianna; Løberg, Magnus; Larsen, Inger Kristin; Kalager, Mette; Holme, Øyvind; Botteri, Edoardo; Bretthauer, Michael & Hoff, Geir (2015). Long-term lifestyle changes after colorectal cancer screening: randomised controlled trial. Gut.  ISSN 0017-5749.  64(8), s 1268- 1276 . doi: 10.1136/gutjnl-2014-307376
  • Garborg, Kjetil Kjeldstad; Kaminski, Michal Filip; Lindenburger, Wolfgang; Wiig, Håvard; Hasund, Audun; Wronska, Ewa; Bie, Rolf Bruun; Kleist, Britta; Løvdal, Leif; Holme, Øyvind; Kalager, Mette; Hoff, Geir & Bretthauer, Michael (2015). Water exchange versus carbon dioxide insufflation in unsedated colonoscopy: A multicenter randomized controlled trial. Endoscopy.  ISSN 0013-726X.  47(3), s 192- 199 . doi: 10.1055/s-0034-1390795
  • Holme, Øyvind; Bretthauer, Michael; Eide, Tor Jacob; Løberg, Else Marit; Grzyb, Krzysztof; Løberg, Magnus; Kalager, Mette; Adami, Hans Olov; Kjellevold, Øystein & Hoff, Geir (2015). Long-term risk of colorectal cancer in individuals with serrated polyps. Gut.  ISSN 0017-5749.  64(6), s 929- 936 . doi: 10.1136/gutjnl-2014-307793
  • Huitfeldt, Anders; Kalager, Mette; robins, james; Hoff, Geir & Hernan, Miguel A. (2015). Methods to Estimate the Comparative Effectiveness of Clinical Strategies that Administer the Same Intervention at Different Times.. Current Epidemiology Reports.  ISSN 2196-2995.  2(3), s 149- 161 . doi: 10.1007/s40471-015-0045-5
  • Løberg, Magnus; Lousdal, Mette Lise; Bretthauer, Michael & Kalager, Mette (2015). Benefits and harms of mammography screening. Breast Cancer Research.  ISSN 1465-542X.  17(1) . doi: 10.1186/s13058-015-0525-z
  • Swanson, Sonja; Holme, Øyvind; Løberg, Magnus; Kalager, Mette; Bretthauer, Michael; Hoff, Geir; Aas, Eline & Hernan, Miguel A. (2015). Bounding the per-protocol effect in randomized trials: an application to colorectal cancer screening. Trials.  ISSN 1745-6215.  16(541) . doi: 10.1186/s13063-015-1056-8
  • Bretthauer, Michael; Løberg, Magnus & Kalager, Mette (2014). Long-term colorectal-cancer mortality after adenoma removal.. New England Journal of Medicine.  ISSN 0028-4793. . doi: 10.1056/NEJMc1411954
  • Hassan, Cesare; Gimeno-García, Antonio; Kalager, Mette; Spada, Cristiano; Zullo, Angelo; Costamagna, Guido; Senore, Carlo; Rex, Douglas Kevin & Quintero, Enrique (2014). Systematic review with meta-analysis: the incidence of advanced neoplasia after polypectomy in patients with and without low-risk adenomas. Alimentary Pharmacology and Therapeutics.  ISSN 0269-2813.  39(9), s 905- 912 . doi: 10.1111/apt.12682
  • Holme, Øyvind; Bretthauer, Michael; Eide, Tor Jacob; Løberg, Else Marit; Grzyb, Krzysztof; Løberg, Magnus; Kalager, Mette; Adami, Hans Olov; Kjellevold, Øystein & Hoff, Geir (2014). Long-term risk of colorectal cancer in individuals with serrated polyps.. Gut.  ISSN 0017-5749. . doi: 10.1136/gutjnl-2014-307793
  • Holme, Øyvind; Løberg, Magnus; Kalager, Mette; Bretthauer, Michael; Hernan, Miguel A.; Aas, Eline; Eide, Tor Jacob; Skovlund, Eva; Schneede, Jørn; Tveit, Magne Kjell & Hoff, Geir (2014). Effect of Flexible Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality A Randomized Clinical Trial. Journal of the American Medical Association (JAMA).  ISSN 0098-7484.  312(6), s 606- 615 . doi: 10.1001/jama.2014.8266
  • Kalager, Mette; Løberg, Magnus; Bretthauer, Michael & Adami, Hans Olov (2014). Comparative analysis of breast cancer mortality following mammography screening in Denmark and Norway. Annals of Oncology.  ISSN 0923-7534.  25(6), s 1137- 1143 . doi: 10.1093/annonc/mdu122
  • Løberg, Magnus; Kalager, Mette; Holme, Øyvind; Hoff, Geir; Adami, Hans Olov & Bretthauer, Michael (2014). Long-Term Colorectal-Cancer Mortality after Adenoma Removal. New England Journal of Medicine.  ISSN 0028-4793.  371(9), s 799- 807 . doi: 10.1056/NEJMoa1315870
  • Bretthauer, Michael & Kalager, Mette (2013). Principles, effectiveness and caveats in screening for cancer. British Journal of Surgery.  ISSN 0007-1323.  100(1), s 55- 65 . doi: 10.1002/bjs.8995
  • Garborg, Kjetil Kjeldstad; Holme, Øyvind; Løberg, Magnus; Kalager, Mette; Adami, Hans Olov & Bretthauer, Michael (2013). Current status of screening for colorectal cancer. Annals of Oncology.  ISSN 0923-7534.  24(8), s 1963- 1972 . doi: 10.1093/annonc/mdt157
  • Hassan, Cesare; Quintero, Enrique; Dumonceau, Jean-Marc; Regula, Jaroslaw; Brandão, Catarina; Chaussade, Stanislas; Dekker, Evelien; Dinis-Ribeiro, Mario; Ferlitsch, Monika; Gimeno-García, Antonio; Hazewinkel, Yark; Jover, Rodrigo; Kalager, Mette; Løberg, Magnus; Pox, Christian; Rembacken, Björn & Lieberman, David (2013). Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy.  ISSN 0013-726X.  45(10), s 842- 851 . doi: 10.1055/s-0033-1344548
  • Thiis-Evensen, Espen; Kalager, Mette; Bretthauer, Michael & Hoff, Geir (2013). Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial. United European Gastroenterology journal.  ISSN 2050-6406.  1(3), s 162- 168 . doi: 10.1177/2050640613483290
  • Kalager, Mette; Adami, Hans-Olov; Bretthauer, Michael & Tamimi, Rulla (2012). Overdiagnosis of Invasive Breast Cancer Due to Mammography Screening: Results From the Norwegian Screening Program. Annals of Internal Medicine.  ISSN 0003-4819.  156(7), s 491- U61 . doi: 10.1059/0003-4819-156-7-201204030-00005
  • Kalager, Mette; Tamimi, Rulla; Bretthauer, Michael & Adami, Hans Olov (2012). Prognosis in women with interval breast cancer: population based observational cohort study. BMJ (British Medical Journal).  ISSN 0959-8146.  345 . doi: 10.1136/bmj.e7536
  • Garborg, Kjetil Kjeldstad; Løberg, Magnus; Matre, Jon; Holme, Øyvind; Kalager, Mette; Hoff, Geir & Bretthauer, Michael (2012). Reduced pain during screening colonoscopy with an ultrathin colonoscope: a randomized controlled trial. Endoscopy.  ISSN 0013-726X.  44(8), s 740- 746 . doi: 10.1055/s-0032-1309755
  • Kalager, Mette; Zelen, Marvin; Langmark, Frøydis Tonning & Adami, Hans-Olov (2010). Effect of Screening Mammography on Breast-Cancer Mortality in Norway. New England Journal of Medicine.  ISSN 0028-4793.  363(13), s 1203- 1210
  • Kalager, Mette; Haldorsen, Tor; Bretthauer, Michael; Hoff, Geir; Thoresen, Steinar & Adami, Hans-Olov (2009). Improved breast cancer survival following introduction of an organized mammography screening program among both screened and unscreened women: a population-based cohort study. Breast Cancer Research.  ISSN 1465-542X.  11(4) . doi: 10.1186/bcr2331
  • Kalager, Mette; Kåresen, Rolf & Wist, Erik (2009). Fylkesvise forskjeller i overlevelse av brystkreft. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  129(24), s 2595- 2600 . doi: 10.4045/tidsskr.09.0024

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  • Holme, Øyvind; Løberg, Magnus; Bretthauer, Michael & Kalager, Mette (2017). Authors' reply to Doherty and Hawkins. BMJ (British Medical Journal).  ISSN 0959-8146.  356 . doi: 10.1136/bmj.j1267
  • Kalager, Mette & Stoltenberg, Camilla (2017). Screening for den enkelte og kunnskap for alle. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137:858(12), s 1- 2 . doi: 10.4045/tidsskr.17.0445
  • Løberg, Magnus; Holme, Øyvind & Kalager, Mette (2017). Aspirin, colorectal cancer, and cause of death: A complex landscape. Journal of Clinical Oncology.  ISSN 0732-183X.  35(5), s 568- 569 . doi: 10.1200/JCO.2016.70.3751
  • Bretthauer, Michael; Kalager, Mette; Adami, Hans Olov & Hoff, Geir (2016). Who Is for CO2? Slow Adoption of Carbon Dioxide Insufflation in Colonoscopy. Annals of Internal Medicine.  ISSN 0003-4819.  165(2), s 145- 6 . doi: 10.7326/M16-0209
  • Bretthauer, Michael; Kaminski, Michal Filip; Hassan, Cecare; Kalager, Mette; Holme, Øyvind; Hoff, Geir; Løberg, Magnus; Regula, Jaroslaw; Castells, A & Adami, Hans Olov (2016). America, We Are Confused: The Updated U.S. Preventive Services Task Force Recommendation on Colorectal Cancer Screening. Annals of Internal Medicine.  ISSN 0003-4819.  166(2), s 139- 140 . doi: 10.7326/M16-1805
  • Kalager, Mette; Adami, Hans Olov & Bretthauer, Michael (2016). Recognizing data generation. New England Journal of Medicine.  ISSN 0028-4793.  374(19), s 1898- 1898 . doi: 10.1056/NEJMc1603789
  • Kalager, Mette; Hagen, Eirik M. & Helsingen, Lise M. (2016). Farlig forretning på frykt. Dagens næringsliv.  ISSN 0803-9372.  127(278), s 30- 30
  • Løberg, Magnus; Kalager, Mette & Bretthauer, Michael (2016). "Randomize, Then Consent" or "Consent, Then Randomize"?: Revitalizing the Issue of Preconsent Randomization.. Epidemiology.  ISSN 1044-3983. . doi: 10.1097/EDE.0000000000000469
  • Schei, Edvin & Kalager, Mette (2016). Annerledes tenkende angstfri. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  136(14/15), s 1212- 1214 . doi: 10.4045/tidsskr.16.0517
  • Frich, Jan C; Kalager, Mette & Bretthauer, Michael (2015). Samvalg er et dårlig begrep. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.  s 12- 12
  • Bretthauer, Michael; Løberg, Magnus & Kalager, Mette (2014). The authors reply. New England Journal of Medicine.  ISSN 0028-4793.  371(21), s 2036- 2037 . doi: 10.1056/NEJMc1411954
  • Holme, Øyvind; Løberg, Magnus & Kalager, Mette (2014). In reply. Journal of the American Medical Association (JAMA).  ISSN 0098-7484.  312(22), s 2411- 2412 . doi: 10.1001/jama.2014.14695
  • Kalager, Mette (2014). Overdiagnosis in breast cancer screening: women have minimal prior awareness of the issue, and their screening intentions are influenced by the size of the risk. Evidence-Based Nursing.  ISSN 1367-6539. . doi: 10.1136/eb-2013-101281
  • Kalager, Mette; Adami, Hans Olov & Bretthauer, Michael (2014). Too much mammography. BMJ (Clinical Research Edition).  ISSN 0959-8138.  348 . doi: 10.1136/bmj.g1403
  • Kalager, Mette & Bretthauer, Michael (2014). Bartens dårlige venner. Dagbladet.  ISSN 0805-3766.
  • Roksund, Gisle; Bretthauer, Michael & Kalager, Mette (2014). En epidemi av diagnoser, ikke sykdom. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Kalager, Mette; Løberg, Magnus & Bretthauer, Michael (2013). Limited use of nonprogram screening in Norway. International Journal of Cancer.  ISSN 0020-7136.  132(7), s 1723- 1724 . doi: 10.1002/ijc.27807
  • Kalager, Mette; Løberg, Magnus; Fønnebø, Vinjar & Bretthauer, Michael (2013). Failure to account for selection-bias. International Journal of Cancer.  ISSN 0020-7136.  133(11), s 2751- 2753 . doi: 10.1002/ijc.28244
  • Kalager, Mette; Adami, Hans Olov; Bretthauer, Michael & Tamimi, Rulla M. (2012). Overdiagnosis of Invasive Breast Cancer due to Mammography Screening RESPONSE. Annals of Internal Medicine.  ISSN 0003-4819.  157(3), s 221- 222
  • Berstad, Paula Marianna; Loberg, Magnus; Kalager, Mette; Jørgensen, Anita; Garborg, Kjetil Kjeldstad; Ruud, Hans-Kristian; Bretthauer, Michael & Hoff, Geir (2012). Risk Stratification for Advanced Colorectal Neoplasia. Cancer Prevention Research.  ISSN 1940-6207.  5(12), s 1405- 1405 . doi: 10.1158/1940-6207.CAPR-12-0383
  • Bretthauer, Michael & Kalager, Mette (2012). Colonoscopy as a Triage Screening Test . New England Journal of Medicine.  ISSN 0028-4793.  366(8), s 759- 760
  • Bretthauer, Michael & Kalager, Mette (2012). Colorectal-Cancer Screening Reply. New England Journal of Medicine.  ISSN 0028-4793.  366(22), s 2131- 2131
  • Garborg, Kjetil Kjeldstad; Loberg, Magnus; Matre, Jon; Holme, Øyvind; Kalager, Mette; Hoff, Geir & Bretthauer, Michael (2012). Improved Colonoscopy Screening With an Ultra Thin Colonoscope: A Randomized Controlled Trial. Gastrointestinal Endoscopy.  ISSN 0016-5107.  75(4), s 179- 180
  • Jørgensen, K; Kalager, Mette; Zahl, Per Henrik & Fønnebø, Vinjar (2012). Comparing attendees with non-attendees in breast screening does not provide useful information about an effect on prognostic features or mortality. Breast Cancer Research and Treatment.  ISSN 0167-6806.  136(2), s 617- 618 . doi: 10.1007/s10549-012-2250-y
  • Kalager, Mette (2012). Letter to the Editor: Hofvind S. Skaane P. Stage distribution of breast cancer diagnosed before and after implementation of population-based mammographic screening. Fortschr Rontgenstr 2012; 184: 437-442. RöFo. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren (Print).  ISSN 1438-9029.  184(8), s 746- 746
  • Kalager, Mette (2012). Primum non nocere. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  (4), s 132- 132 . doi: 10.4045/tidsskr.12.0079
  • Smith, Robert A.; Kerlikowske, Karla; Miglioretti, Diana L. & Kalager, Mette (2012). Mammography Screening for Breast Cancer. New England Journal of Medicine.  ISSN 0028-4793.  367(21) . doi: 10.1056/NEJMclde1212888
  • Kalager, Mette (2011). Regression of screening-detected breast cancer. The Lancet Oncology.  ISSN 1470-2045.  12(12), s 1083- 1084 . doi: 10.1016/S1470-2045(11)70262-5

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Published Dec. 9, 2014 10:31 AM - Last modified Jan. 10, 2017 2:01 PM