Anne Spurkland

Professor - Molecular Immunology
Image of Anne Spurkland
Norwegian version of this page
Phone +47-22851125
Mobile phone +47-41574078
Room 2501
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1105 Blindern 0317 OSLO

Academic interests

  • Autoimmune disease
  • T cell activation
  • Molecular immunology
  • Genetics
  • Neuroinflammation

Courses taught

  • Anatomy

Background

Education

  • MD. University of Oslo, 1986
  • PhD Universvity of Oslo, 1993
  • Specialised in Immunology and Transfusion Medicine, 2000

Positions held

  • 1988-1992: Research fellow, Norwegian Research Council
  • 1993-1994: Resident physician, Red Cross Blood bank, Oslo
  • 1995: Resident physician, Department of immunology and blood transfusion, Ullevål Hospital, Oslo
  • 1995-1999: Researcher, Institute of transplantation Immunology, Rikshospitalet
  • 2000-2001: Resident physician, Institute of Immunology, Rikshospitalet
  • 2001: Assistant professor, UiO
  • 2001-to present: Professor, UiO

Positions held

  • Member of the Norwegian Academy of Science and Letters

Collaboration

  • Partner in Genetic Analysis of Multiple Sclerosis in Europeans (GAMES) 2000-dd
  • Partner in International Multiple Sclerosis Consortium (IMSGC) 2008-dd
  • Member of Management Committee COST Neurinfnet 2009-2011
Tags: Blood and immunology, Genetic and epidemiology, Brain and nervous system, Life science

Publications

  • Hem, Cecilie Anne Dahl; Ekornhol, Marianne; Granum, Stine; Gjerstad, Vibeke Sundvold & Spurkland, Anne (2017). DUBLETT: CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein. Scandinavian Journal of Immunology.  ISSN 0300-9475.  85(2), s 104- 112 . doi: 10.1111/sji.12513
  • Berge, Tone; Leikfoss, Ingvild Sørum; Brorson, Ina Skaara; Bos, Steffan Daniel; Page, Christian; Gustavsen, Marte Wendel; Bjølgerud, Anja; Holmøy, Trygve; Celius, Elisabeth Gulowsen; Damoiseaux, J.; Smolders, J; Harbo, Hanne Flinstad & Spurkland, Anne (2016). The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by Vitamin D in CD4+ T cells. Genes and Immunity.  ISSN 1466-4879.  17(2), s 118- 127 . doi: 10.1038/gene.2015.61
  • Gordon, Emma; Fukuhara, D.; Weström, S.; Padhan, N.; Sjöström, Elisabeth; van Meeteren, L.; He, Liqun; Orsenigo, F.; Dejana, E.; Bentley, K.; Spurkland, Anne & Claesson-Welsh, Lena (2016). The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation. Science Signaling.  ISSN 1937-9145.  9(437) . doi: 10.1126/scisignal.aad9256
  • Enqvist, Monika; Ask, Eivind Heggernes; Forslund, Elin; Carlsten, Mattias; Abrahamsen, Greger; Béziat, Vivien; Andersson, Sandra; Schaffer, Marie; Spurkland, Anne; Bryceson, Yenan; Önfelt, Björn & Malmberg, Karl-Johan (2015). Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. Journal of Immunology.  ISSN 0022-1767.  194(9), s 4518- 4527 . doi: 10.4049/jimmunol.1401972
  • Eriksen, Agnete Bratsberg; Berge, Tone; Gustavsen, Marte Wendel; Leikfoss, Ingvild Sørum; Bos, Steffan Daniel; Spurkland, Anne; Harbo, Hanne Flinstad & Blomhoff, Heidi Kiil (2015). Retinoic acid enhances the levelels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  278, s 11- 18 . doi: 10.1016/j.jneuroim.2014.11.019
  • Eriksen, Agnete Bratsberg; Torgersen, Maria Lyngaas; Lillebø Holm, Kristine; Abrahamsen, Greger; Spurkland, Anne; Moskaug, Jan Øivind; Simonsen, Anne & Blomhoff, Heidi Kiil (2015). Retinoic acid-induced IgG Production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy.  ISSN 1554-8627.  11(3), s 460- 471 . doi: 10.1080/15548627.2015.1009797
  • Hem, Cecilie Anne Dahl; Gjerstad, Vibeke Sundvold; Granum, Stine; Koll, Lise; Abrahamsen, Greger; Buday, Laszlo & Spurkland, Anne (2015). T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells. Cell Communication and Signaling.  ISSN 1478-811X.  13(1) . doi: 10.1186/s12964-015-0109-7
  • Leikfoss, Ingvild Sørum; Keshari, Pankaj Kumar; Gustavsen, Marte Wendel; Bjølgerud, Anja; Brorson, Ina Skaara; Celius, Elisabeth Gulowsen; Spurkland, Anne; Bos, Steffan Daniel; Harbo, Hanne Flinstad & Berge, Tone (2015). Multiple sclerosis risk allele in CLEC16A acts as an expression quantitative trait locus for CLEC16A and SOCS1 in CD4+ T cells. PLoS ONE.  ISSN 1932-6203.  10>e0132957(7) . doi: 10.1371/journal.pone.0132957 Full text in Research Archive
  • Moussa, P; Abrahamsen, Greger; Fodil, N; Gopalakrishnan, Ramakrishna Prabhu; Mancini, M; Dissen, Erik; Sæther, Per Christian; Wiltshire, SA; Boivin, GA; Caignard, G; Spurkland, Anne & Vidal, SM (2015). Reduced MCMV Δm157 viral clearance in the absence of TSAd. Scientific Reports.  ISSN 2045-2322.  5 . doi: 10.1038/srep09219 Full text in Research Archive
  • Moutsianas, Loukas; Jostins, Luke; Beecham, Ashley H.; Dilthey, Alexander T.; Xifara, Dionysia K.; Ban, Maria; Shah, Tejas S.; Patsopoulos, Nikolaos A.; Alfredsson, Lars; Anderson, Carl A.; Attfield, Katherine E.; Baranzini, Sergio E.; Barrett, Jeffrey; Binder, Thomas M.C.; Booth, David; Buck, Dorothea; Celius, Elisabeth Gulowsen; Cotsapas, Chris; D'Alfonso, Sandra; Dendrou, Calliope A.; Donnelly, Peter; Dubois, Bénédicte; Fontaine, Bertrand; Fugger, Lars; Goris, An; Gourraud, Pierr-Antoine; Graetz, Christiane; Hemmer, Bernhard; Hillert, Jan; Kockum, Ingrid; Leslie, Stephen; Lill, Christina M.; Martinelli-Boneschi, Filippo; Oksenberg, Jorge R.; Olsson, Tomas; Oturai, Annette; Saarela, Janna; Søndergaard, Helle Bach; Spurkland, Anne; Taylor, Bruce; Winkelmann, Juliane; Zipp, Frauke; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Spencer, Chris C.A.; Stewart, Graeme; Hafler, David A; Ivinson, Adrian J.; Harbo, Hanne Flinstad; Hauser, Stephen L.; De Jager, Philip L.; Compston, Alastair; McCauley, Jacob L.; Sawcer, Stephen & McVean, Gil (2015). Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics.  ISSN 1061-4036.  47(10), s 1107- 1113 . doi: 10.1038/ng.3395
  • Andersen, Thorny Cesilie Bie; Lindsjø, Kjersti; Hem, Cecilie Anne Dahl; Koll, Lise; Kristiansen, Per Eugen; Skjeldal, Lars; Andreotti, Amy H. & Spurkland, Anne (2014). Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO. BMC Biotechnology.  ISSN 1472-6750.  14(3) . doi: 10.1186/1472-6750-14-3 Full text in Research Archive
  • Damotte, V; Guillot-Noel, Lena; Patsopoulos, Nikolaos A.; Madireddy, L; Behi, M El; Ban, Maria; Baranzini, Sergio; Barcellos, Lisa; Beecham, Gary; Beecham, Ashley; Bernardinelli, L; Booth, David; Bos, Steffan Daniel; Buck, Dorothea; Bush, William; Comabella, Manuel; Compston, Alastair; Cotsapas, Chris; Cournu-rebeixisabelle, Isabelle; Cree, Bruce; d'Alfonso, Sandra; Daly, Mark; Damotte, Vincent; Davis, Mary; Bakker, Paul de; De Jager, Philip L; Dubois, Benedicte; Esposito, Federica; Fontaine, Bertrand; Goris, An; Gourraud, Pierre-Antoine; Green, Todd; Celius, Elisabeth Gulowsen; Hadjixenofontos, Athena; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen; Hawkins, Clive; Hemmer, Bernhard; Hillert, Jan; Hintzen, Rogier; Horáková, Dana; Ivinson, Adrian J; Kemppinen, Anu; Kira, Jun-ichi; Kockum, Ingrid; Lincoln, Robin; Martin, Roland; Boneschi, Filippo martinelli; McCauley, Jacob L.; Mero, Inger-Lise; Oksenberg, Jorge; Olsson, Tomas; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret; Rioux, John; Saarela, Janna; Sawcer, Stephen; Schnetz-boutaud, Nathalie; Sellebjerg, Finn; Soendergaard, Helle; Sorensen, Per Soelberg; Spurkland, Anne; Stankovich, Jim; Stewart, Graeme; Taylor, Bruce; Ticca, Anna; West, Sandra; Zipp, Frauke; Blackwell, Jenefer m; Bramon, Elvira; Brown, Matthew A; Casas, Juan Pablo; Corvin, Aiden; Jankowski, Janusz; Markus, Hugh s; Mathew, Christopher G.; Palmer, Colin NA; Plomin, Robert; Rautanen, Anna; Trembath, Richard c; Viswanathan, Ananth c; Wood, Nicholas W.; Spencer, Chris ca; Band, Gavin; Bellenguez, Celine; Freeman, Colin; Hellenthal, Garrett; Giannoulatou, Eleni; Pirinen, Matti; Pearson, Richard; Strange, Amy; Su, Zhan; Vukcevic, Damjan; Donnelly, Peter; Langford, Cordelia; Hunt, Sarah E; Edkins, Sarah; Gwilliam, Rhian; Blackburn, Hannah; Bumpstead, Suzannah J.; Dronov, Serge; Gillman, Matthew; Gray, Emma; Hammond, Naomi; Jayakumar, Alagurevathi; Mccann, Owen t; Liddle, Jennifer; Potter, Simon C; Ravindrarajah, Rathi; Ricketts, Michelle; Waller, Matthew J; Weston, Paul; Widaa, Sara; Whittaker, Pamela; Barroso, Ines; Deloukas, Panos; Dilthey, Alexander; Leslie, Stephen; Moutsianas, Loukas; Perez, Marc l; Mcvean, Gil; Mccarthy, Mark i; Baranzini, SE; Cournu-Rebeix, I & Fontaine, B. (2014). A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes and Immunity.  ISSN 1466-4879.  15, s 126- 132 . doi: 10.1038/gene.2013.70
  • Goris, An; Van Setten, Jessica; Diekstra, Frank; Ripke, Stephan; Patsopoulos, Nikolaos A.; Sawcer, Stephen; Ban, Maria; Baranzini, Sergio; Barcellos, Lisa; Beecham, Gary; Beecham, Ashley; Bernardinelli, L; Booth, David; Bos, Steffan Daniel; Buck, Dorothea; Bush, William; Comabella, Manuel; Compston, Alastair; Cotsapas, Chris; Cournu-Rebeix, Isabelle; Cree, Bruce; d'Alfonso, Sandra; Daly, Mark; Damotte, Vincent; Davis, Mary; Bakker, Paul de; De Jager, Philip L; Dubois, Benedicte; Esposito, Federica; Fontaine, Bertrand; Gourraud, Pierre-Antoine; Green, Todd; Celius, Elisabeth Gulowsen; Hadjixenofontos, Athena; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen; Hawkins, Clive; Hemmer, Bernhard; Hillert, Jan; Hintzen, Rogier; Horáková, Dana; Ivinson, Adrian J; Kemppinen, Anu; Kira, Jun-ichi; Kockum, Ingrid; Lincoln, Robin; Martin, Roland; Boneschi, Filippo martinelli; McCauley, Jacob L.; Mero, Inger-Lise; Oksenberg, Jorge; Olsson, Tomas; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret; Rioux, John; Saarela, Janna; Schnetz-boutaud, Nathalie; Sellebjerg, Finn; Soendergaard, Helle; Sorensen, Per Soelberg; Spurkland, Anne; Stankovich, Jim; Stewart, Graeme; Taylor, Bruce; Ticca, Anna; West, Sandra; Zipp, Frauke; van Es, Michael; Bahlo, M; Booth, DR; Broadley, SA; Brown, MA; Foote, SJ; Griffiths, LR; Kilpatrick, TJ; Lechner-Scott, J; Moscato, P; Perreau, VM; Rubio, JP; Scott, RJ; Stankovich, J; Taylor, BV; Wiley, J; Clarke, G; Cox, MB; Csurhes, PA; Danoy, P; Drysdale, K; Field, J; Greer, JM; Guru, P; Hadler, J; Mcmorran, BJ; Jensen, CJ; Johnson, JL; McCallum, R.; Merriman, M.; Merriman, T.; Pryce, K; Stewart, GJ; Tajouri, L; Wilkins, EJ; Browning, BL; Browning, SR; Perera, D; Broadley, S.; Butzkueven, H.; Carroll, WM; Chapman, C.; Kermode, AG; Marriott, M; Mason, D; Heard, RN; Pender, MP; Slee, M.; Tubridy, N; Willoughby, E; Andersen, Peter M.; Melki, Judith; Meininger, Vincent; Hardiman, Orla; Landers, John E; Brown, Robert H; Shatunov, Aleksey; Leigh, Nigel; Al-Chalabi, Ammar; Shaw, Christopher E; Traynor, Bryan J.; Chio, Adriano; Restagno, Gabriella; Mora, Gabriele; Ophoff, Roel A.; Oksenberg, Jorge R.; Van Damme, Philip; Robberecht, Wim; van den Berg, Leonard H.; Veldink, Jan H & de Bakker, Paul I.W. (2014). No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Human Molecular Genetics.  ISSN 0964-6906.  23(7), s 1916- 1922 . doi: 10.1093/hmg/ddt574
  • Granum, Stine; Gjerstad, Vibeke Sundvold; Gopalakrishnan, Ramakrishna Prabhu; Berge, Tone; Koll, Lise; Abrahamsen, Greger; Sørlie, Morten & Spurkland, Anne (2014). The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. Science Signaling.  ISSN 1937-9145.  7:ra118(355) . doi: 10.1126/scisignal.2005384
  • Pandya, Abhilash D.; Leergaard, Trygve Brauns; Dissen, Erik; Haraldsen, Guttorm & Spurkland, Anne (2014). Expression of the T cell-specific adapter protein in human tissues. Scandinavian Journal of Immunology.  ISSN 0300-9475.  80(3), s 169- 179 . doi: 10.1111/sji.12199
  • Sundqvist, Emilie; Buck, Dorothea; Warnke, Clemens; Albrecht, Eva; Gieger, Christian; Khademi, Mohsen; Lima Bomfim, Izaura; Fogdell-Hahn, Anna; Link, Jenny; Alfredsson, Lars; Søndergaard, Helle Bach; Hillert, Jan; Barcellos, Lisa; Booth, David; McCauley, Jacob L.; Comabella, Manuel; Compston, Alastair; d'Alfonso, Sandra; de Jager, Philip; Fontaine, Bertrand; Goris, An; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen L; Hawkins, Clive; Ivinson, Adrian; Martin, Roland; Boneschi, Fillippo Martinelli; Oksenberg, Jorge; Patsopoulos, Nikolaos; Pericak-Vance, Margaret; Saarela, Janna; Sawcer, Stephen; Spurkland, Anne; Stewart, Graeme; Zipp, Frauke; Oturai, Annette B.; Hemmer, Bernhard; Kockum, Ingrid & Olsson, Tomas (2014). JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants. PLoS Pathogens.  ISSN 1553-7366.  10(4) . doi: 10.1371/journal.ppat.1004084
  • Baranzini, SE; Celius, E.G.; Elovaara, I; Harbo, HF; Hillert, J; Myhr, Kjell-Morten; Sørensen, PS; Spurkland, A; Sawcer, S; Hauser, SL; Oksenberg, JR; Khankhanian, Pouya; Patsopoulos, Nikolaos A.; Li, Michael; Stankovich, Jim; Cotsapas, Chris; Søndergaard, Helle Bach; Ban, Maria; Barizzone, Nadia; Bergamaschi, Laura; Booth, David; Buck, Dorothea; Cavalla, Paola; Celius, Elisabeth G.; Comabella, Manuel; Comi, Giancarlo; Compston, Alastair; Cournu-Rebeix, Isabelle; D’alfonso, Sandra; Damotte, Vincent; Din, Lennox; Dubois, Benedicte; Elovaara, Irina; Esposito, Federica; Fontaine, Bertrand; Franke, Andre; Goris, An; Gourraud, Pierre-Antoine; Graetz, Christiane; Guerini, Franca R.; Guillot-Noel, Lena; Hafler, David A; Hakonarson, Hakon; Hall, Per; Hamsten, Anders; Harbo, Hanne Flinstad; Bernhard, Hemmer; Hillert, Jan; Kemppinen, Anu; Ingrid, Kockum; Koivisto, Keijo; Larsson, Malin; Lathrop, Mark; Leone, Maurizio; Lill, Christina M.; Macciardi, Fabio; Martin, Roland; Martinelli, Vittorio; Martinelli-Boneschi, Filippo; McCauley, Jacob L.; Naldi, Paoloa; Olsson, Tomas; Oturai, Annette; Pericak-Vance, Margaret A.; Perla, Franco; Reunanen, Mauri; Saarela, Janna; Saker-Delye, Safa; Salvetti, Marco; Sellebjerg, Finn; Sørensen, Per Soelberg; Spurkland, Anne; Stewart, Graeme; Taylor, Bruce; Tienari, Pentti; Winkelmann, Juliane; Wellcome Trust Case Control, Consortium 2; Zipp, Frauke; Ivinson, Adrian J; Haines, Jonathan L.; Sawcer, Stephen; DeJager, Philip; Hauser, Stephen L & Oksenberg, Jorge R. (2013). Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls. American Journal of Human Genetics.  ISSN 0002-9297.  s 854- 865 . doi: 10.1016/j.ajhg.2013.04.019
  • Beecham, Ashley H.; Patsopoulos, NA; Xifara, DK; Davis, MF; Kemppinen, A; Cotsapas, C; Shah, TS; Spencer, C; Booth, D; Goris, A; Oturai, A; Saarela, J; Fontaine, B; Hemmer, B; Martin, C; Zipp, F; D'Alfonso, S; Martinelli-Boneschi, F; Taylor, B; Harbo, Hanne Flinstad; Kockum, I; Hillert, J; Olsson, T; Ban, M; Oksenberg, JR; Hintzen, R; Barcellos, LF; Agliardi, C; Alfredsson, L; Alizadeh, M; Anderson, C; Andrews, R; Sondergaard, HB; Baker, A; Band, G; Baranzini, SE; Barizzone, N; Barrett, J; Bellenguez, C; Bergamaschi, L; Bernardinelli, L; Berthele, A; Biberacher, V; Binder, TMC; Blackburn, H; Bomfim, IL; Brambilla, P; Broadley, S; Brochet, B; Brundin, L; Buck, D; Butzkueven, H; Caillier, SJ; Camu, W; Carpentier, W; Cavalla, P; Celius, Elisabeth Gulowsen; Coman, I; Comi, G; Corrado, L; Cosemans, L; Cournu-Rebeix, I; Cree, BAC; Cusi, D; Damotte, V; Defer, G; Delgado, SR; Deloukas, P; di Sapio, A; Dilthey, AT; Donnelly, P; Dubois, B; Duddy, M; Edkins, S; Elovaara, I; Esposito, F; Evangelou, N; Fiddes, B; Field, J; Franke, A; Freeman, C; Frohlich, IY; Galimberti, D; Gieger, C; Gourraud, PA; Graetz, C; Graham, A; Grummel, V; Guaschino, C; Hadjixenofontos, A; Hakonarson, H; Halfpenny, C; Hall, G; Hall, P; Hamsten, A; Harley, J; Harrower, T; Hawkins, C; Hellenthal, G; Hillier, C; Hobart, J; Hoshi, M; Hunt, SE; Jagodic, M; Jelcic, I; Jochim, A; Kendall, B; Kermode, A; Kilpatrick, T; Koivisto, K; Konidari, I; Korn, T; Kronsbein, H; Langford, C; Larsson, M; Lathrop, M; Lebrun-Frenay, C; Lechner-Scott, J; Lee, MH; Leone, MA; Leppa, V; Liberatore, G; Lie, Benedicte Alexandra; Lill, CM; Linden, M; Link, J; Luessi, F; Lycke, J; Macciardi, F; Mannisto, S; Manrique, CP; Martin, R; Martinelli, V; Mason, D; Mazibrada, G; McCabe, C; Mero, Inger-Lise; Mescheriakova, J; Moutsianas, L; Myhr, Kjell-Morten; Nagels, G; Nicholas, R; Nilsson, P; Piehl, F; Pirinen, M; Price, SE; Quach, H; Reunanen, M; Robberecht, W; Robertson, NP; Rodegher, M; Rog, D; Salvetti, M; Schnetz-Boutaud, NC; Sellebjerg, F; Selter, RC; Schaefer, C; Shaunak, S; Shen, L; Shields, S; Siffrin, V; Slee, M; Sorensen, PS; Sorosina, M; Sospedra, M; Spurkland, Anne; Strange, A; Sundqvist, E; Thijs, V; Thorpe, J; Ticca, A; Tienari, P; van Duijn, C; Visser, EM; Vucic, S; Westerlind, H; Wiley, JS; Wilkins, A; Wilson, JF; Winkelmann, J; Zajicek, J; Zindler, E; Haines, JL; Pericak-Vance, MA; Ivinson, AJ; Stewart, G; Hafler, D; Hauser, SL; Compston, A; McVean, G; De Jager, P; Sawcer, SJ & McCauley, JL (2013). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics.  ISSN 1061-4036.  45(11), s 1353- 1360 . doi: 10.1038/ng.2770
  • Jacobsen, Johanne Tracey; Gjerstad, Vibeke Sundvold; Skjeldal, Frode Miltzow; Andersen, Jan Terje; Abrahamsen, Greger; Bakke, Oddmund; Spurkland, Anne & Bogen, Bjarne (2013). B-cell tolerance to the B-cell receptor variable regions. European Journal of Immunology.  ISSN 0014-2980.  43(10), s 2577- 2587 . doi: 10.1002/eji.201243203
  • Leikfoss, Ingvild Sørum; Mero, Inger-Lise; Dahle, Maria Krudtaa; Lie, Benedicte Alexandra; Harbo, Hanne Flinstad; Spurkland, Anne & Berge, Tone (2013). Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus. Genes and Immunity.  ISSN 1466-4879.  14(1), s 62- 66 . doi: 10.1038/gene.2012.52
  • Rosella, Mechelli; Renato, Umeton; Policano, Claudia; Annibali, Viviana; Giulia, Coarelli; Ricigliano, Vito A. G.; Vittori, Danila; Fornasiero, Arianna; Buscarinu, Maria Chiara; Sawcer, Stephen; Hellenthal, Garrett; Pirinen, Matti; Spencer, Chris C A; Patsopoulos, Nikolaos; Mousianas, Loukas; Dithey, Alexander; Su, Zhan; Freeman, Colin; Hunt, Sarah E; Edkins, Sarah; Gray, Emma; Booth, David R; Potter, Simon C; Goris, An; Band, Gavin; Oturai, Annette Bang; Strange, Amy; Saarela, Janna; Bellenguez, Celine; Fontaine, Bertrand; Gillman, Matthew; Hemmer, Bernhard; Gwilliam, Rhian; Zipp, Frauke; Jayakumar, Akagurevathi; Martin, Roland; Leslie, Stephen; Hawkins, Stanley; Giannolatou, Eleni; D`alfonso, Sandra; Blackburn, Hannah; Boneschi, Fillippo Martinelli; Liddle, Jennifer; Harbo, Hanne Flinstad; Perez, Marc L; Spurkland, Anne; Waller, Matthew J; Mycko, Marcin P; Ricketts, Michelle; Comabella, Manuel; Celius, Elisabeth Gulowsen; Lorentzen, Åslaug Rudjord; Mero, Inger-Lise; Myhr, Kjell-Morten & SMESTAD, CATHRINE (2013). A ‘‘candidate-interactome’’ aggregate analysis of genome-wide association data in multiple sclerosis. PLoS ONE.  ISSN 1932-6203.  8(5) . doi: 10.1371/journal.pone.0063300
  • Berge, Tone; Grønningsæter, Ingrid Helene; Lorvik, Kristina Berg; Abrahamsen, Greger; Granum, Stine; Gjerstad, Vibeke Sundvold; Corthay, Alexandre; Bogen, Bjarne & Spurkland, Anne (2012). SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice. PLoS ONE.  ISSN 1932-6203.  7(10)
  • Sun, Zuyue; Li, Xiujuan; Massena, Sara; Kutschera, Simone; Padhan, Narendra; Gualandi, Laura; Gjerstad, Vibeke Sundvold; Gustafsson, Karin; Choy, Wing Wen; Zang, Guangxiang; Quach, My; Jansson, Leif; Phillipson, Mia; Abid, Md Ruhul; Spurkland, Anne & Claesson-Welsh, Lena (2012). VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd. Journal of Experimental Medicine.  ISSN 0022-1007.  209(7), s 1363- 1377 . doi: 10.1084/jem.20111343
  • Harbo, Hanne Flinstad; Lorentzen, Åslaug Rudjord; Lie, Benedicte Alexandra; Celius, Elisabeth Gulowsen & Spurkland, Anne (2011). Nytt genkart for multippel sklerose. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  131(21), s 2126- 2130
  • Mero, Inger-Lise; Ban, Maria; Lorentzen, Åslaug Rudjord; SMESTAD, CATHRINE; Celius, Elisabeth Gulowsen; Sæther, Hanne Skarpodde; Saeedi, Haleh; Viken, Marte K; Skinningsrud, Beate; Undlien, Dag Erik; Aarseth, Jan Harald; Myhr, Kjell-Morten; Granum, Stine; Spurkland, Anne; Sawcer, Stephen; Compston, Alastair; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2011). Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus. Genes and Immunity.  ISSN 1466-4879.  12(3), s 191- 198 . doi: 10.1038/gene.2010.59
  • Sawcer, S; Hellenthal, G; Pirinen, M; Spencer, CCA; Patsopoulos, NA; Moutsianas, L; Dilthey, A; Su, Z; Freeman, C; Hunt, SE; Edkins, S; Gray, E; Booth, DR; Potter, SC; Goris, A; Band, G; Oturai, AB; Strange, A; Saarela, J; Bellenguez, C; Fontaine, B; Gillman, M; Hemmer, B; Gwilliam, R; Zipp, F; Jayakumar, A; Martin, R; Leslie, S; Hawkins, S; Giannoulatou, E; D'alfonso, S; Blackburn, H; Boneschi, FM; Liddle, J; Harbo, Hanne Flinstad; Perez, ML; Spurkland, Anne; Waller, MJ; Mycko, MP; Ricketts, M; Comabella, M; Hammond, N; Kockum, I; McCann, OT; Ban, M; Whittaker, P; Kemppinen, A; Weston, P; Hawkins, C; Widaa, S; Zajicek, J; Dronov, S; Robertson, N; Bumpstead, SJ; Barcellos, LF; Ravindrarajah, R; Abraham, R; Alfredsson, L; Ardlie, K; Aubin, C; Baker, A; Baker, K; Baranzini, SE; Bergamaschi, L; Bergamaschi, R; Bernstein, A; Berthele, A; Boggild, M; Bradfield, JP; Brassat, D; Broadley, SA; Buck, D; Butzkueven, H; Capra, R; Carroll, WM; Cavalla, P; Celius, Elisabeth Gulowsen; Cepok, S; Chiavacci, R; Clerget-Darpoux, F; Clysters, K; Comi, G; Cossburn, M; Cournu-Rebeix, I; Cox, MB; Cozen, W; Cree, BAC; Cross, AH; Cusi, D; Daly, MJ; Davis, E; de Bakker, PIW; Debouverie, M; D'hooghe, MB; Dixon, K; Dobosi, R; Dubois, B; Ellinghaus, D; Elovaara, I; Esposito, F; Fontenille, C; Foote, S; Franke, A; Galimberti, D; Ghezzi, A; Glessner, J; Gomez, R; Gout, O; Graham, C; Grant, SFA; Guerini, FR; Hakonarson, H; Hall, P; Hamsten, A; Hartung, HP; Heard, RN; Heath, S; Hobart, J; Hoshi, M; Infante-Duarte, C; Ingram, G; Ingram, W; Islam, T; Jagodic, M; Kabesch, M; Kermode, AG; Kilpatrick, TJ; Kim, C; Klopp, N; Koivisto, K; Larsson, M; Lathrop, M; Lechner-Scott, JS; Leone, MA; Leppa, V; Liljedahl, U; Bomfim, IL; Lincoln, RR; Link, J; Liu, JJ; Lorentzen, Åslaug Rudjord; Lupoli, S; Macciardi, F; Mack, T; Marriott, M; Martinelli, V; Mason, D; McCauley, JL; Mentch, F; Mero, Inger-Lise; Mihalova, T; Montalban, X; Mottershead, J; Myhr, Kjell-Morten; Naldi, P; Ollier, W; Page, A; Palotie, A; Pelletier, J; Piccio, L; Pickersgill, T; Piehl, F; Pobywajlo, S; Quach, HL; Ramsay, PP; Reunanen, M; Reynolds, R; Rioux, J; Rodegher, M; Roesner, S; Rubio, JP; Ruckert, IM; Salvetti, M; Salvi, E; Santaniello, A; Schaefer, CA; Schreiber, S; Schulze, C; Scott, RJ; Sellebjerg, F; Selmaj, KW; Sexton, D; Shen, L; Simms-Acuna, B; Skidmore, S; Sleiman, PMA; SMESTAD, CATHRINE; Sorensen, PS; Sondergaard, HB; Stankovich, J; Strange, RC; Sulonen, AM; Sundqvist, E; Syvanen, AC; Taddeo, F; Taylor, B; Blackwell, JM; Tienari, P; Bramon, E; Tourbah, A; Brown, MA; Tronczynska, E; Casas, JP; Tubridy, N; Corvin, A; Vickery, J; Jankowski, J; Villoslada, P; Markus, HS; Wang, K; Mathew, CG; Wason, J; Palmer, CNA; Wichmann, HE; Plomin, R; Willoughby, E; Rautanen, A; Winkelmann, J; Wittig, M; Trembath, RC; Yaouanq, J; Viswanathan, AC; Zhang, HT; Wood, NW; Zuvich, R; Deloukas, P; Langford, C; Duncanson, A; Oksenberg, JR; Pericak-Vance, MA; Haines, JL; Olsson, T; Hillert, J; Ivinson, AJ; De Jager, PL; Peltonen, L; Stewart, GJ; Hafler, DA; Hauser, SL; McVean, G; Donnelly, Peter & Compston, Alastair (2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature.  ISSN 0028-0836.  476(7359), s 214- 219 . doi: 10.1038/nature10251
  • Berge, Tone; Gjerstad, Vibeke Sundvold; Granum, Stine; Andersen, Thorny Cesilie Bie; Holthe, Gunn Bodil; Claesson-Welsh, L; Andreotti, Amy H.; Inngjerdingen, Marit & Spurkland, Anne (2010). T Cell Specific Adapter Protein (TSAd) Interacts with Tec Kinase ITK to Promote CXCL12 Induced Migration of Human and Murine T Cells. PLoS ONE.  ISSN 1932-6203.  5(3) . doi: 10.1371/journal.pone.0009761
  • Esposito, Floriana; Patsopoulos, NA; Cepok, Sabine; Kockum, I; Leppa, V; Booth, DR; Heard, RN; Stewart, GJ; Cox, M; Scott, RJ; Lechner-Scott, J; Goris, A; Dobosi, R; Dubois, B; Rioux, JD; Oturai, AB; Søndergaard, HB; Sellebjerg, F; Sørensen, PS; Reunanen, M; Koivisto, K; Cournu-Rebeix, I; Fontaine, B; Winkelmann, J; Gieger, C; Infante-Duarte, C; Zipp, F; Bergamaschi, L; Leone, M; Bergamaschi, R; Cavalla, P; Lorentzen, ÅR; Mero, Inger-Lise; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Spurkland, Anne; Comabella, M; Brynedal, B; Alfredsson, L; Bernardinelli, L; Robertson, NB; Hawkins, CP; Barcellos, LF; Beecham, G; Bush, W; Cree, BAC; Daly, MJ; Ivinson, AJ; Aublin, C; Compston, A; D´Alfonso, S; Haines, JL; Hauser, SL; Hemmer, B; Hillert, J; McMcauley, JL; Oksenberg, Jorge; Olsson, T; Palotie, A; Peltonen, L; Pericak-Vance, MA; Saarela, J; Sawcer, SJ; Stranger, B; Boneschi, FM; Comi, G; Hafler, DA; de Bakker, PIW & De Jaeger, PL (2010). IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. Genes and Immunity.  ISSN 1466-4879.  11(5), s 397- 405 . doi: 10.1038/gene.2010.28
  • Kolltveit, Kristin Melkevik; Schreurs, Olav Joseph F; Østrem, Janet M; Søland, Tine Merete; Khuu, Cuong; Berge, Tone; Messelt, Edvard Berger; Hayashi, Katsuhiko; Granum, Stine; Spurkland, Anne & Schenck, Karl (2010). Expression of the T-cell-specific adapter protein in oral epithelium. European Journal of Oral Sciences.  ISSN 0909-8836.  118(2), s 159- 167
  • Mero, Inger-Lise; Lorentzen, Åslaug Rudjord; SMESTAD, CATHRINE; Ban, Maria; Celius, Elisabeth Gulowsen; Aarseth, Jan; Myhr, Kjell-Morten; Link, Jenny; Olsson, Tomas; Hillert, Jan; Kockum, Ingrid; Masterman, T; Oturai, AB; Sondergaard, HB; Sellebjerg, F; Saarela, J; Kemppinen, A; Elovaara, I; Spurkland, Anne; Dudbridge, F; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2010). A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. European Journal of Human Genetics.  ISSN 1018-4813.  18(4), s 502- 504 . doi: 10.1038/ejhg.2009.195
  • Lorentzen, Åslaug Rudjord; Karlsen, TH; Olsson, M; Smestad, C; Mero, IL; Woldseth, B; Sun, JY; Senitzer, D; Celius, EG; Thorsby, E; Spurkland, Anne; Lie, BA & Harbo, Hanne Flinstad (2009). Killer Immunoglobulin-like Receptor Ligand HLA-Bw4 Protects Against Multiple Sclerosis. Annals of Neurology.  ISSN 0364-5134.  65(6), s 658- 666 . doi: 10.1002/ana.21695
  • Mero, Inger Lise; Lorentzen, Åslaug Rudjord; Ban, Maria; SMESTAD, CATHRINE; Celius, Elisabeth G; Aarseth, Jan; Myhr, Kjell Morten; Link, Jenny; Hillert, Jan; Olsson, Tomas; Kochum, Ingrid; Masterman, T; Oturai, A; Søndergaard, HB; Sellebjerg, Finn; Saaerla, Janna; Kemppinen, Anu; Spurkland, Anne; Dubridge, F; Lie, BA & Harbo, Hanne Flinstad (2009). A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. European Journal of Human Genetics.  ISSN 1018-4813. . doi: 10.1038/ejhg.2009.195
  • Ban, M; Goris, A; Lorentzen, Åslaug Rudjord; Baker, A; Mihalova, T; Ingram, G; Booth, DR; Heard, RN; Stewart, GJ; Bogaert, E; Dubois, B; Harbo, Hanne Flinstad; Celius, Elisabeth Gulowsen; Spurkland, Anne; Strange, R; Hawkins, C; Robertson, NP; Dudbridge, F; Wason, J; De Jager, PL; Hafler, D; Rioux, JD; Ivinson, AJ; McCauley, JL; Pericak-Vance, M; Oksenberg, JR; Hauser, SL; Sexton, D; Haines, J; Sawcer, S & Compston, A (2009). Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. European Journal of Human Genetics.  ISSN 1018-4813.  17(10), s 1309- 1313 . doi: 10.1038/ejhg.2009.41
  • Ban, Maria; Booth, David R; Heard, Robert N; Stewart, Graeme J; Goris, An; Dobosi, Rita; Lorentzen, Åslaug Rudjord; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Spurkland, Anne; Dubois, Benedicte; Olsson, Tomas; Hillert, Jan; Kockum, Ingrid; Link, Jenny; Baker, Amie; Sawcer, Stephen; Compston, Alastair; Mihalova, Tania; Strange, Richard; Hawkins, Clive; Ingram, Gillian; Robertson, Neil P; De Jager, Philip L; Hafler, David A; Barcellos, Lisa F; Ivinson, Adrian; Periack-Vance, Margaret; Oksenberg, Jorge R; Hauser, Stephen L; McCauley, Jacob L; Sexton, David & Haines, Jonathan (2009). The expanding genetic overlap between multiple sclerosis and type I diabetes. Genes and Immunity.  ISSN 1466-4879.  10(1), s 11- 14 . doi: 10.1038/gene.2008.83
  • Holmøy, Trygve; Harbo, hanne F.; Vartdal, Frode & Spurkland, Anne (2009). Genetic and Molecular Approaches to the Immunopathogenesis of Multiple Sclerosis: An Update. Current molecular medicine.  ISSN 1566-5240.  9(5), s 591- 611
  • Jagodic, Maja; Colacios, Celine; Nohra, Rita; Dejean, Anne S.; Beyeen, Amennai Daniel; Khademi, Mohsen; Casemayou, Audrey; Lamouroux, Lucille; Duthoit, Christine; Papapietro, Olivier; Sjöholm, Louise; Bernard, Isabelle; Lagrange, Dominique; Dahlman, Ingrid; Lundmark, Frida; Oturai, Annette Bang; Soendergaard, Helle B; Kemppinen, Anu; Saarela, Janna; Tienari, Pentti J.; Harbo, Hanne Flinstad; Spurkland, Anne; Ramagopalan, Sreeram V.; Sadovnick, Dessa A.; Ebers, George C.; Seddighzadeh, Maria; Klareskog, Lars; Alfredsson, Lars; Padyukov, Leonid; Hillert, Jan; Clanet, Michel; Edan, Gilles; Fontaine, Bertrand; Fournie, Gilbert J.; Kockum, Ingrid; Saoudi, Abdelhadi & Olsson, Tomas (2009). A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis. Science Translational Medicine.  ISSN 1946-6234.  1(10) . doi: 10.1126/scitranslmed.3000278
  • Lorentzen, Åslaug R; Smestad, Cathrine; Lie, Benedicte A; Lie, BA; Oturai, AB; Oturai, Annette; Åkesson, Eva; Akesson, E; Saarela, Janna; Myhr, Kjell-Morten; Vartdal, Frode; Celius, Elisabeth G; Sorensen, PS; Sørensen, Per S; Hillert, Jan; Spurkland, Anne; Harbo, Hanne F & Harbo, HF (2008). The SH2D2A gene and susceptibility to multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  197, s 152- 158 . doi: 10.1016/j.jneuroim.2008.04.037
  • Granum, Stine; Andersen, Thorny C. B.; Sørlie, Morten; Jørgensen, Marit; Koll, Lise; Berge, Tone; Lea, Tor; Fleckenstein, Burkhard; Spurkland, Anne & Sundvold-Gjerstad, Vibeke (2008). Modulation of Lck function through multisite docking to T cell-specific adapter protein. Journal of Biological Chemistry.  ISSN 0021-9258.  283(32), s 21909- 21919
  • Granum, Stine; Andersen, Thorny Cesilie Bie; Sørlie, Morten; Jorgensen, M; Koll, Lise; Berge, Tone; Lea, Tor Erling; Fleckenstein, B; Spurkland, Anne & Gjerstad, Vibeke Sundvold (2008). Modulation of Lck function through multisite docking to T cell-specific adapter protein. Journal of Biological Chemistry.  ISSN 0021-9258.  283, s 21909- 21919 . doi: 10.1074/jbc.M800871200
  • Kolltveit, Kristin Melkevik; Granum, Stine; Aasheim, HC; Forsbring, Monika; Gjerstad, Vibeke Sundvold; Dai, KZ; Molberg, Øyvind; Schjetne, KW; Bogen, B; Shapiro, VS; Johansen, Finn Eirik; Schenck, Karl & Spurkland, Anne (2008). Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level. Molecular Immunology.  ISSN 0161-5890.  45 . doi: 10.1016/j.molimm.2007.11.005
  • Datta, Pameli; Harbo, Hanne F; Ryder, Lars P.; Akesson, E; Åkesson, Elisabeth; Benedikz, John; Celius, Elisabeth G; Andersen, Oluf; Myhe, KM; Myhr, Kjell-Morten; Sandberg-Wollheim, Magnhild; Hillert, Jan; Svejgaard, Arne; Sørensen, Per Soelberg; Sorensen, PS; Spurkland, Anne & Oturai, Annette (2007). A follow-up study of Nordic multiple sclerosis candidate gene regions. Multiple Sclerosis.  ISSN 1352-4585.  13(5), s 584- 589 . doi: 10.1177/1352458506071790
  • Knudsen, Gun Peggy Strømstad; Harbo, Hanne Flinstad; Smestad, C; Celius, EG; Akesson, E; Oturai, A; Ryder, LP; Spurkland, Anne & Ørstavik, Karen Helene (2007). X chromosome inactivation in females with multiple sclerosis. European Journal of Neurology.  ISSN 1351-5101.  14, s 1392- 1396 . doi: 10.1111/j.1468-1331.2007.01987.x
  • Smestad, C; Brynedal, B; Jonasdottir, G; Lorentzen, Åslaug Rudjord; Masterman, T; Akesson, E; Spurkland, Anne; Lie, BA; Palmgren, J; Celius, EG; Hillert, J & Harbo, Hanne Flinstad (2007). The impact of HLA-A and-DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients. European Journal of Neurology.  ISSN 1351-5101.  14, s 835- 840 . doi: 10.1111/j.1468-1331.2007.01825.x
  • Gjerstad, Vibeke Sundvold; Granum, Stine; Berge, Tone; Andersen, Thorny Cesilie Bie; Kolltveit, Kristin Melkevik & Spurkland, Anne (2007). T cell specific adapter protein in cell signalling and autoimmunity, In Noah Isakov (ed.),  Lymphocyte Activation and Signal Transduction.  Transworld Research Network.  ISBN 978-81-7895-281-9.  12.  s 211 - 220
  • Harbo, HF & Spurkland, Anne (2007). Genetics in multiple sclerosis: past and future perspectives. Acta Neurologica Scandinavica.  ISSN 0001-6314.  115
  • Lie, BA; Dupuy, Berit Myhre; Spurkland, Anne; Fernandez-Vina, MA; Hagelberg, Erika & Thorsby, Erik (2007). Molecular genetic studies of natives on Easter Island: evidence of an early European and Amerindian contribution to the Polynesian gene pool. Tissue Antigens.  ISSN 0001-2815.  69, s 10- 18 . doi: 10.1111/j.1399-0039.2006.00717.x
  • Wiencke, Kristine; Karlsen, Hemming Tom; Boberg, Kirsten Muri; Thorsby, Erik; Schrumpf, Erik; Lie, Benedicte Alexandra & Spurkland, Anne (2007). Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes. Tissue Antigens.  ISSN 0001-2815.  69, s 161- 169 . doi: 10.1111/j.1399-0039.2006.00738.x
  • Harbo, Hanne Flinstad; Ekstrom, PO; Lorentzen, Åslaug Rudjord; Gjerstad, Vibeke Sundvold; Celius, EG; Sawcer, Stephen & Spurkland, Anne (2006). Coding region polymorphisms in T cell signal transduction genes. Prevalence and association to development of multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  177, s 40- 45
  • Granum, Stine; Gjerstad, Vibeke Sundvold; Dai, Kezheng; Kolltveit, Kristin Melkevik; Hildebrand, Kjersti; Huitfeldt, Henrik; Lea, T & Spurkland, Anne (2006). Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7. BMC Immunology.  ISSN 1471-2172.  7, s 15
  • Spurkland, Anne & Sollid, Ludvig Magne (2006). Mapping genes and pathways in autoimmune disease. Trends in immunology.  ISSN 1471-4906.  27, s 336- 342
  • Wiencke, Kristine; Boberg, Kirsten Muri; Donaldson, P; Harbo, Hanne Flinstad; Ling, V; Schrumpf, Erik & Spurkland, Anne (2006). No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  41
  • Matsumoto, T; Bohman, S; Dixelius, J; Berge, Tone; Dimberg, A; Magnusson, P; Wang, L; Wikner, C; Qi, JH; Wernstedt, C; Wu, J; Bruheim, Skjalg; Mugishima, H; Mukhopadhyay, D; Spurkland, Anne & Claesson-Welsh, L (2005). VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis. EMBO Journal.  ISSN 0261-4189.  24
  • Gjerstad, Vibeke Sundvold; Granum, Stine; Mustelin, T; Andersen, Thorny Cesilie Bie; Berge, Tone; Shapiro, MJ; Shapiro, VS; Spurkland, Anne & Lea, Tor Erling (2005). The C terminus of T cell-specific adapter protein (TSAd) is necessary for TSAd-mediated inhibition of Lck activity. European Journal of Immunology.  ISSN 0014-2980.  35(5), s 1612- 1620
  • Lie, BA; Flam, ST; Dahlen, H; Dupuy, Berit Myhre; Spurkland, Anne; Hagelberg, Erika & Thorsby, Erik (2005). High-resolution HLA genotyping of individuals from Easter Island reveals admixture both of European and possible American Indian origin. Tissue Antigens.  ISSN 0001-2815.  66(5), s 564- 564
  • Lorentzen, Åslaug Rudjord; Celius, Elisabeth Gulowsen; Ekstrøm, Per Olaf; Wiencke, Kristine; Lie, Benedicte Alexandra; Myhr, KM; Ling, V; Thorsby, Erik; Vartdal, Frode; Spurkland, Anne & Harbo, Hanne Flinstad (2005). Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients. Journal of Neuroimmunology.  ISSN 0165-5728.  166
  • Etokebe, Godfrey Essien; Abrahamsen, Tore G; Bogen, Bjarne & Spurkland, Anne (2004). Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography . Scandinavian Journal of Immunology.  ISSN 0300-9475.  59, s 496- 503
  • Flesland, Øystein; Ip, LS; Storlien, AS; Spurkland, Anne; Larsen, J & Solheim, Bjarte G. (2004). Michrochimerism in immune competent patients related to the leucocyte content of the transfused red blood cell concentrates. Transfusion and Apheresis Science.  ISSN 1473-0502.  31, s 173- 180
  • Harbo, Hanne Flinstad; Lie, Benedicte Alexandra; Sawcer, Stephen; Celius, EG; Dai, Kezheng; Oturai, Anette; Hillert, Jan; Lorentzen, Åslaug Rudjord; Laaksonen, Mikko; Myhr, Kjell Morten; Ryder, Lars P.; Fredrikson, S.; Nyland, Harald I.; Sørensen, Per Soelberg; Sandberg-Wollheim, Magnhild; Andersen, Oluf; Svejgaard, Arne; Edland, A.; Mellgren, Svein Ivar; Compston, Alistair; Vartdal, Frode & Spurkland, Anne (2004). Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. Tissue Antigens.  ISSN 0001-2815.  63, s 237- 247
  • Ke-Zheng, Dai; Johansen, Finn-Erik; Kolltveit, Kristin Melkevik; Aasheim, Hans-Christian; Dembic, Zlatko; Vartdal, Frode & Spurkland, Anne (2004). Transcriptional activation of the SH2D2A gene is dependent on a cyclic adenosine 5' monophosphate responsive element in the proximal SH2D2A promoter. Journal of Immunology.  ISSN 0022-1767.  172, s 6144- 6151
  • Smerdel, Anna; Dai, Kezheng; Lorentzen, Åslaug Rudjord; Flatø, Berit; Maslinski, S; Thorsby, Erik; Førre, Øystein Thorleiv & Spurkland, Anne (2004). Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene. Genes and Immunity.  ISSN 1466-4879.  5(4), s 310- 312
  • Dai, Kezheng; Johansen, Finn Eirik; Kolltveit, Kristin Melkevik; Aasheim, Hans-Christian; Dembic, Zlatko; Vartdal, Frode & Spurkland, Anne (2004). Transcriptional activation of the SH2D2A gene is dependent on a cyclic adenosine 5'-monophosphate-responsive element in the proximal SH2D2A promoter. Journal of Immunology.  ISSN 0022-1767.  172, s 6144- 6151
  • Flornes, Line Marie; Bryceson, Yenan T.; Spurkland, Anne; Lorentzen, JC; Dissen, Erik & Fossum, Sigbjørn (2004). Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. Immunogenetics.  ISSN 0093-7711.  56, s 506- 517
  • Nejad, S; Bryceson, Yenan T.; Dissen, Erik; Sundvold-Gjerstad, V; Naper, Christian; Rolstad, Bent; Spurkland, Anne & Vaage, John Torgils (2004). cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells . Immunogenetics.  ISSN 0093-7711.  56(5), s 338- 342 . doi: 10.1007/s00251-004-0695-9
  • Oturai, AB; Ryder, LP; Fredrikson, S; Myhr, KM; Celius, EG; Harbo, HF; Andersen, O; Akesson, E; Hillert, J; Madsen, HO; Nyland, Harald Inge; Spurkland, A; Datta, P; Svejgaard, A; Sørensen, PS & Sorensenl, PS (2004). Concordance for disease course and age of onset in Scandinavian multiple sclerosis coaffected sib pairs. Multiple Sclerosis.  ISSN 1352-4585.  10, s 5- 8
  • Wiencke, Kristine; Louka, Andrew; Spurkland, Anne; Vatn, Morten H; Schrumpf, Erik & Boberg, Kirsten Muri (2004). Association of matrix metalloproteinase-1 and-3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients. Journal of Hepatology.  ISSN 0168-8278.  41, s 209- 214

View all works in Cristin

View all works in Cristin

  • Spurkland, Anne (2016). Gjenkjent .
  • Spurkland, Anne (2016). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Spurkland, Anne (2016). Multiple sclerosis genetics.
  • Spurkland, Anne (2016). Regulation of Lck specificity in TCR signal initiation.
  • Spurkland, Anne (2016). Skam .
  • Spurkland, Anne (2016). Skamløs? .
  • Spurkland, Anne (2016, 25. mars). Slik virker immunforsvarets hukommelse . [Internett].  Forskning.no.
  • Spurkland, Anne (2013). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Spurkland, Anne (2013). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Tilset, Mats; Boye, Erik & Spurkland, Anne (2013). Glemte sykdommer rammer 1 milliard. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Leikfoss, Ingvild S; Mero, Inger-Lise; Dahle, Maria Krudtaa; Lie, Benedicte Alexandra; Harbo, Hanne Flinstad; Spurkland, Anne & Berge, Tone (2012). Multiple Sclerosis Associated Single Nucleotide Polymorphisms in CLEC16A Correlate with Reduced SOCS1 and DEXI Expression in Thymic Samples. Scandinavian Journal of Immunology.  ISSN 0300-9475.  76(2), s 196- 196
  • Spurkland, Anne (2012). Maten, tarmen og immunforsvaret.
  • Spurkland, Anne (2012). Om cøliaki og om frie kaker.
  • Spurkland, Anne (2012). Om matallergi og frie kaker.
  • Flåm, Karoline H. & Spurkland, Anne (2011, 08. oktober). Menn blir sykere enn kvinner .  VG.
  • Huszenicza, Zsuzsa; Hem, Cecilie Anne Dahl; Koll, Lise; Ekornhol, Marianne; Sundvold-Gjerstad, Vibeke; Granum, Stine & Spurkland, Anne (2011). Identification of Novel TSAd Interaction Partners. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 353- 354
  • Kjensli, Bjørnar & Spurkland, Anne (2011, 01. oktober). Kakebakingens kjemi . [Internett].  http://www.forskning.no/.
  • Spurkland, Anne (2011, 15. oktober). Ekko kroppen spesial. [Radio].  NRK P2.
  • Sundvold-Gjerstad, Vibeke; Kristiansen, Tone Fredsvik; Granum, Stine; Berge, Tone; Koster, Gerbrand; Skjeldal, Frode Miltzow; Koll, Lise; Bakke, Oddmund & Spurkland, Anne (2011). T cell Specific Adapter Protein (TSAd) Relocates the Tec Family Protein Tyrosine Kinase Itk from the Plasma Membrane to the Perinuclear Area. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 359- 359
  • Sørum, Ingvild; Mero, Inger-Lise; Gustavsen, Marte Wendel; Muggerud, Aslaug; Sæther, Hanne Skarpodde; Lie, Benedicte Alexandra; Spurkland, Anne; Berge, Tone & Harbo, Hanne Flinstad (2011). Molecular Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 377- 377
  • Booth, DR; Heard, RN; Stewart, GJ; Cox, M; Scott, RJ; Lechner-Scott, J; Goris, A; Dobosi, R; Dubois, B; Saarela, J; Leppa, V; Peltonen, L; Pirttila, T; Cournu-Rebeix, I; Fontaine, B; Bergamaschi, L; D'Alfonso, S; Leone, M; Lorentzen, A.R.; Harbo, Hanne Flinstad; Celius, Elisabeth Gulowsen; Spurkland, Anne; Link, J; Kockum, I; Olsson, T; Hillert, J; Ban, M; Baker, A; Kemppinen, A; Sawcer, S; Compston, A; Robertson, NP; De Jager, PL; Hafler, DA; Barcellos, LF; Ivinson, AJ; McCauley, JL; Pericak-Vance, MA; Oksenberg, JR; Hauser, SL; Sexton, D & Haines, J (2010). Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nature Genetics.  ISSN 1061-4036.  42(6), s 469- 470
  • Lorentzen, AR; Karlsen, Tom Hemming; Olsson, M; SMESTAD, CATHRINE; Mero, Inger-Lise; Woldseth, B; Sun, JY; Senitzer, David; Celius, Elisabeth Gulowsen; Thorsby, Erik; Spurkland, Anne; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2009). Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis. European Journal of Neurology.  ISSN 1351-5101.  16, s 19- 19
  • Mero, Inger-Lise; Lorentzen, AR; Ban, Maria; SMESTAD, CATHRINE; Celius, Elisabeth Gulowsen; Aarseth, JH; Myhr, Kjell Morten; Link, Jenny; Hillert, Jan; Olsson, Tomas; Kockum, Ingrid; Masterman, T.; Oturai, Anette; Søndergaard, Henrik; Sellebjerg, Finn; Saarela, J; Kemppinen, A; Spurkland, Anne; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2009). The TYK2 gene is associated with susceptibility to multiple sclerosis. Multiple Sclerosis.  ISSN 1352-4585.  15(9), s S186- S186
  • Lorentzen, Åslaug Rudjord; Karlsen, Tom Hemming; Olsson, Marita; Smestad, Cathrine; Mero, Inger-Lise; Woldseth, Bente; Sun, Ji-Yao; Senitzer, David; Celius, Elisabeth Gulowsen; Thorsby, Erik; Spurkland, Anne; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2008). Protection against multiple sclerosis conferred by carriage of the inhibitory killer immunoglobulin-like receptors (KIRs) ligand HLA-Bw4.
  • Kantarci, OH & Spurkland, Anne (2008). Parent of origin in multiple sclerosis: Understanding inheritance in complex neurologic diseases. Neurology.  ISSN 0028-3878.  71, s 786- 787
  • Lorentzen, Åslaug Rudjord; Ban, Maria; Booth, David; Heard, Robert; Stewart, Graeme; Goris, An; Dobosi, Rita; Dubois, Benedicte; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Spurkland, Anne; Olsson, Tomas; Kockum, Ingrid; Link, Jenny; Hillert, Jan; Mihalova, Tania; Strange, Richard; Hawkins, Clive; Ingram, Gillian; Robertson, Neil; De Jager, Philip L; Hafler, David A; Barcellos, Lisa; Ivinson, Adrian; Pericak-Vance, Margaret; Oksenberg, Jorge; Hauser, Stephen L; McCauley, Jacob; Sexton, David; Haines, Jonathan; Baker, Amie; Sawcer, Stephen & Compston, Alastair (2008). The expanding genetic overlap between multiple sclerosis and type 1 diabetes.
  • Sawcer, Stephen; Booth, David; Heard, Robert; Stewart, Graeme; An, Goris; Dobosi, Rita; Dubois, Benedicte; Oturai, Annette; Soendergaard, Helle B; Sellebjerg, Finn; Saarela, Janna; Leppa, Virpi; Palotie, Aarno; Peltonen, Leena; Fontaine, Bertrand; Cournu-Rebeix, Isabelle; Clerget-Darpoux, Francoise; Weber, Frank; Holsboer, Florian; Muller-Myhsok, Bertram; Rieckmann, Peter; Kroner, Antje; Graham, Colin; Vandenbroeck, Koen; Hawkins, Stanley; D'Alfonso, Sandra; Bergamaschi, Laura; Naldi, Paola; Guerini, Franca R; Salvetti, Marco; Galimberti, Daniela; Hintzen, Rogier; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Celius, Elisabeth Gulowsen; Spurkland, Anne; Cucca, Francesco; Marrosu, Maria Giovanna; Comabella, Manuel; Montalban, Xavier; Villoslada, Pablo; Olsson, Tomas; Kockum, Ingrid; Hillert, Jan; Ban, Maria; Walton, Amie; Compston, Alastair; Hawkins, Clive; Mihalova, Tania; Robertson, Neil; Ingram, Gillian; De Jager, Philip L; Hafler, David A; Rioux, John; Daly, Mark; Barcellos, Lisa; Ivinson, Adrian; Periack-Vance, Margaret; Oksenberg, Jorge; Hauser, Stephen L; McCauley, Jacob; Sexton, David & Haines, Jonathan (2008). Refining genetic associations in multiple sclerosis. Lancet Neurology.  ISSN 1474-4422.  7(7), s 567- 569 . doi: 10.1016/S1474-4422(08)70122-4
  • SMESTAD, CATHRINE; Brynedal, B; Jonasdottir, G; Lorentzen, AR; Masterman, T.; Akesson, E; Spurkland, Anne; Lie, Benedicte Alexandra; Palmgren, J; Celius, Elisabeth Gulowsen; Hillert, J & Harbo, Hanne Flinstad (2007). The impact of HLA-A and HLA-DRB1 alleles on age at onset, disease course and severity in Scandinavian multiple sclerosis patients. European Journal of Neurology.  ISSN 1351-5101.  14, s 22- 22
  • Lie, BA; T Flam, S; Dupuy, Berit Myhre; Spurkland, Anne; Fernandez-Vina, MA; Hagelberg, Erika & Thorsby, E (2006). Evidence of Amerindian ancestry and early European admixture in Easter Island revealed by high-resolution HLA genotyping. Tissue Antigens.  ISSN 0001-2815.  67, s 458- 458
  • Lorentzen, AR; SMESTAD, CATHRINE; Ekstrøm, Per Olaf; Oturai, Annette Bang; Åkesson, Eva; Saarela, Janna; Myhr, Kjell-Morten; Lie, Benedicte Alexandra; Celius, Elisabeth Gulowsen; Sorensen, PS; Hillert, Jan; Spurkland, Anne & Harbo, Hanne Flinstad (2006). The role of SH2D2A gene polymorphisms in multiple sclerosis. Multiple Sclerosis.  ISSN 1352-4585.  12(Suppl 1), s S72- S72
  • Lorentzen, Åslaug Rudjord; Celius, EG; Ekstrom, P; Wiencke, Kristine; Lie, Benedicte Alexandra; Myhr, KM; Ling, V; Thorsby, Erik; Vartdal, Frode; Spurkland, Anne & Harbo, Hanne Flinstad (2005). The CD28/CTLA4/ICOS gene region does not show assosiation in Norwegian multiple sclerosis patients. Genes and Immunity.  ISSN 1466-4879.  6
  • Wiencke, Kristine; Karlsen, TH; Boberg, Kirsten Muri; Harbo, Hanne Flinstad; Lie, Benedicte Alexandra; Thorsby, Erik; Schrumpf, Erik & Spurkland, Anne (2005). Association to the HLA-DR6 haplotype in PSC: Additional effects in the HLA class I/extended class I region. Journal of Hepatology.  ISSN 0168-8278.  42
  • Flesland, Øystein; Spurkland, Anne & Solheim, Bjarte G. (2004). Michrochimerism in immune competent patients related to the leucocyte content of the transfused red blood cell concentrates. Vox Sanguinis.  ISSN 0042-9007.  87, s 143
  • Spurkland, Anne (2004). Adopsjon som forskningsmetode: Hva er arv og hva er miljø blant koreanere i utlendighet?. Adopsjonsforum.  ISSN 0802-7617.  03/2004, s 24- 25

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Published Apr. 13, 2011 2:40 PM - Last modified May 16, 2017 5:15 PM