Jan E. Brinchmann

Image of Jan E. Brinchmann
Norwegian version of this page
Phone +47-22840489
Room 2244
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1112 Blindern 0317 OSLO

Academic interests

  • Stem cell biology
  • Tissue engineering
  • Cell therapy

Courses taught

PBL

Background

Education:

  • 1991: PhD in HIV immunology and virology, University of Oslo
  • 1987: Specialist in internal medicine
  • 1976: MD, Royal College of Surgeons in Ireland

Work:

  • 2009 - Group leader, Norwegian Center for Stem Cell Research, Rikshospitalet and University of Oslo
  • 2005 - Section head, Cell therapy, Institute of Immunology, Rikshospitalet University Hospital, Oslo
  • 1998 - 2005 Medical director, Cell Processing Laboratory, Rikshospitalet University Hospital, Oslo, Norway
  • 1995 - 2005 Senior scientist, Institute of Immunology, Rikshospitalet
  • 1992 - 1995 Post doc. scientist, Institute of Immunology, Rikshospitalet
  • 1986 - 1991 Doctoral fellow, Institute of Immunology, Rikshospitalet
  • 1985 - 1986 Physician, Department of Medicine, Akershus University Hospital, Norway
  • 1982 - 1985 Registrar, Department of Medicine, Woden Valley Hospital and Royal Canberra Hospital, Canberra, Australia
  • 1979 - 1982 Resident medical officer, Department of Infectious Diseases, Ullevål Hospital, Oslo, Norway

Awards

  • 1990: Domagk-Bayer Prize for best paper within infectious diseases: NOK 10.000
  • 1991: Medinnova Prize for excellent research concepts, NOK 100.000

Collaboration

  • Norwegian Center for Stem Cell Research, Jan E. Brinchmann group
  • Department of Immunology, Oslo University Hospital Rikshospitalet
  • Professor Lars Engebretsen, Department of Orthopedics, OUS Ullevål sykehus
  • Dr. Svend Aakhus, Department of Cardiology, OUS Rikshospitalet
  • Professor Philippe Collas, Department of Biochemistry, Institute of Basic Madical Sciences, UoO
  • Dr. Leonardo Meza-Zepeda, Microarray Core Facility, OUS Radiumhospitalet
  • Dr. Tarjei Mikkelsen, Broad Institute, Massachusetts Institute of Technology and Harvard Stem Cell Institute
Tags: Stem cells, Muscolo-Skeletal system, Heart vascular and lungs

Publications

  • Brinchmann, Bendik Christian; Skuland, Tonje Schwach; Rambøl, Mia Marie-Elisabeth; Szöke, Krisztina; Brinchmann, Jan E.; Gutleb, Arno C.; Moschini, Elisa; Kubátová, Alena; Kukowski, Klara; Le Ferrec, Eric; Lagadic-Gossmann, Dominique; Schwarze, Per Everhard; Låg, Marit; Refsnes, Magne Arnold; Øvrevik, Johan & Holme, Jørn Andreas (2018). Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s). Particle and Fibre Toxicology.  ISSN 1743-8977.  15 . doi: 10.1186/s12989-018-0257-1
  • Behnan, Jinan; Stangeland, Biljana; Hosainey, Sayied Abdol Mohieb; Joel, Mrinal; Olsen, Thale Kristin; Micci, Francesca; Glover, Joel; Isakson, Pauline & Brinchmann, Jan E. (2017). Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene.  ISSN 0950-9232.  36(4), s 570- 584 . doi: 10.1038/onc.2016.230 Show summary
  • Kosik-Kozioł, Alicja; Costantini, Marco; Bolek, Tomasz; Szöke, Krisztina; Barbetta, Andrea; Brinchmann, Jan E. & Święszkowski, Wojciech (2017). PLA short sub-micron fiber reinforcement of 3D bioprinted alginate constructs for cartilage regeneration. Biofabrication.  ISSN 1758-5082.  9:044105(4), s 1- 14 . doi: 10.1088/1758-5090/aa90d7
  • Szöke, Krisztina; Daňková, Jana; Buzgo, Matej; Amler, Evžen; Brinchmann, Jan E. & Østrup, Esben (2017). The effect of medium composition on deposition of collagen type 1 and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow. Process Biochemistry.  ISSN 1359-5113.  59, s 321- 328 . doi: 10.1016/j.procbio.2016.10.011
  • Wollert, Kai C.; Meyer, Gerd P.; Müller-Ehmsen, Jochen; Tschöpe, Carsten; Bonarjee, Vernon V S; Larsen, Alf Inge; May, Andreas E.; Empen, Klaus; Chorianopoulos, Emmanuel; Tebbe, Ulrich; Waltenberger, Johannes; Mahrholdt, Heiko; Ritter, Benedikta; Pirr, Jens; Fischer, Dieter; Korf-Klingebiel, Mortimer; Arseniev, Lubomir; Heuft, Hans-Gert; Brinchmann, Jan E.; Messinger, Diethelm; Hertenstein, Bernd; Ganser, Arnold; Katus, Hugo A.; Felix, Stephan B.; Gawaz, Meinrad P.; Dickstein, Kenneth; Schultheiss, Heinz-Peter; Ladage, Dennis; Greulich, Simon & Bauersachs, Johann (2017). Intracoronary autologous bone marrow cell transfer after myocardial infarction: The BOOST-2 randomised placebo-controlled clinical trial. European Heart Journal.  ISSN 0195-668X.  38(39), s 2936- 2943 . doi: 10.1093/eurheartj/ehx188
  • Karlsen, Tommy Aleksander; De Souza, Gustavo Antonio; Ødegård, Bjørn; Engebretsen, Lars & Brinchmann, Jan E. (2016). microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1beta-induced Osteoarthritis.. Molecular Therapy - Nucleic Acids.  ISSN 2162-2531.  5, s e373 . doi: 10.1038/mtna.2016.64
  • Aae, Tommy Frøseth; Randsborg, Per-Henrik; Breen, Anne Berg; Visnes, Håvard; Vindfeld, Søren; Sivertsen, Einar; Løken, Sverre Bertrand; Brinchmann, Jan E.; Hanvold, Heidi Andreassen & Årøen, Asbjørn (2016). Norwegian Cartilage Project - a study protocol for a double-blinded randomized controlled trail comparing arthroscopic microfracture with debridement in focal cartilage defects in the knee. BMC Musculoskeletal Disorders.  ISSN 1471-2474.  17:292 . doi: 10.1186/s12891-016-1156-y
  • Behnan, Jinan; Stangeland, Biljana; Langella, Tiziana; Finocchiaro, Gaetano; Murrell, Wayne & Brinchmann, Jan E. (2016). Ultrasonic Surgical Aspirate is a Reliable Source for Culturing Glioblastoma Stem Cells. Scientific Reports.  ISSN 2045-2322.  6 . doi: 10.1038/srep32788 Full text in Research Archive.
  • Costantini, Marco; Idaszek, Joanna; Szoke, Krisztina; Jaroszewicz, Jakub; Dentini, Mariella; Barbetta, Andrea; Brinchmann, Jan E. & Swieszkowski, Wojciech (2016). 3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation. Biofabrication.  ISSN 1758-5082.  8(3) . doi: 10.1088/1758-5090/8/3/035002

View all works in Cristin

  • Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn & Brinchmann, Jan E. (2017). Early molecular events during in vitro chondrogenesisi, In Kerry Atkinson (ed.),  The biology and therapeutic Application of mesenchymal cells.  Wiley-Blackwell.  ISBN 978-1-118-90751-1.  Chapter 14.  s 167 - 190

View all works in Cristin

Published Apr. 13, 2011 2:40 PM - Last modified Apr. 9, 2014 9:44 AM