Farrukh Abbas Chaudhry

Image of Farrukh Abbas Chaudhry
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Phone +47-22859132
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Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1105 Blindern 0317 OSLO

Academic Interests

Chaudhry is currently focused on the functional mechanisms involved in the replenishment of neurotransmitters glutamate and GABA in the central nervous system.

In particular, his group's research investigates the molecular mechanisms of the transport proteins involved in the glutamate/GABA-glutamine cycle, and their physiological and pathophysiological roles in a variety of disease conditions.

Higher education and employment history

Research:

  • 2000 - 2005:  Career scholarship holder, Research Council of Norway, "Amino acid transport systems and synaptic transmission", Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo.

Education:

  • 2002:  Dr. med. (MD, PhD), Project "Amino acid transporters at the synapse", research conducted in the Department of Anatomy, University of Oslo, as well as at the Departments of Neurology and Physiology, University of California San Francisco (UCSF).
  • 1996:  Medical Doctor, University of Oslo.

Honoraria

  • 2007:  Outstanding Young Investigator Award, Research Council of Norway.
  • 2006:  Anders Jahre’s award for medical research (“The award is a recognition of outstanding scientific achievement or research results in the Nordic countries”).
  • 2005:  “Young Investigator Lectureship Award”, The International Society for Neurochemistry (ISN). (“Recognizes research achievements of promising young scientists involved in neurochemical research”)
  • 2003:  His Majesty the King’s Gold Medal for the best PhD thesis at the Medical Faculty, University of Oslo.
  • 2001 - 2006:  Career-stipend, Research Council of Norway.
  • 1997 - 1998:  US-Norway Fulbright Foundation for Educational Exchange Award.
  • 1997:  The Unger-Vetlesen Medical Fund Award.

Academic and professional committees

  • 2009 - present:  Member of the Norwegian Academy of Science and Letters.
  • 2007 - present:  Reviewing editor for “Tidsskriftet for Dnlf” (Journal for the association of Norwegian Physicians).

Communication of science

Chaudhry is committed to the dissemination of science and has published more than 35 original publications in peer reviewed journals such as Cell, Science, Neuron (2x), EMBO J, PNAS (2x), J Neurosci (8x), Cereb Cortex (2x), and J Am Soc Nephrol, as well as reviews and book chapters in such publications as Annu Rev Pharmacol Toxicol and Handb Exp Pharmacol.  In addition, he publishes regularly in newspapes, gives public lectures and has been an invited speaker at international conferences more than 20 times.

Research activities and key achievements

  • Opened the field of H+-coupled amino acid transporters by identifying SN1 (Cell 1999) and functionally characterizing several homologues (PNAS 2000, J Neurosci 2002).
  • Demonstrated the existence of channel like activities within the transporter proteins (EMBO J 2001).
  • Demonstrated involvement of the amino acid transporter SAT2 in glutamatergic retrograde signaling (Cereb Cortex 2008b) and association of the homologous SAT1 with GABAergic neurotransmission (Front Neuroanat 2010).
  • Demonstrated involvement of SN1 in pH homeostasis during chronic metabolic acidosis (J Am Soc Nephrol 2005), its membrane trafficking (J Neurosci 2011) and potential involvement in insulin release from pancreas (Biochem Biophys Res Commun 2009).
  • Identified the significance of a vesicular glutamate transporter, VGLUT3, and demonstrated potential for differential release of multiple transmitters from a single nerve terminal (PNAS 2003; J Comp Neurol 2004; Cereb Cortex 2008a).
  • Contributed to the analysis of the first knock-out of a VGLUT, showing its importance for the maintenance of synaptic vesicles (Science 2004).
  • High resolution quantitative electron microscopic localization of transporter proteins (Neuron 1995, J Biol Chem 1998; J Neurosci 1998, Neuron 2010).

 

Tags: Glutamate, Glutamine, GABA, Glutamine transporters, Neuro cell signaling, Insulin secretion, pH regulation

Publications

  • Lancellotti, Patrizio; Pellikka, Patricia A.; Budts, Werner; Chaudhry, Farrukh Abbas; Donal, Erwan; Dulgheru, Raluca; Edvardsen, Thor; Garbi, Madalina; Ha, Jong-Won; Kane, Garvan C.; Kreeger, Joe; Mertens, Luc; Pibarot, Philippe; Picano, Eugenio; Ryan, Thomas; Tsutsui, Jeane M. & Varga, Albert (2017). The clinical use of stress echocardiography in non-ischaemic heart disease: recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. Journal of the American Society of Echocardiography.  ISSN 0894-7317.  30(2), s 101- 138 . doi: 10.1016/j.echo.2016.10.016
  • Idland, Ane-Victoria; Wyller, Torgeir Bruun; Støen, Randi; Eri, Lars Magne; Frihagen, Frede Jon; Ræder, Johan; Chaudhry, Farrukh Abbas; Hansson, Oskar; Zetterberg, Henrik; Blennow, Kaj; Bogdanovic, Nenad; Brækhus, Anne & Watne, Leiv Otto (2016). Preclinical amyloid-β and axonal degeneration pathology in delirium. Journal of Alzheimer's Disease.  ISSN 1387-2877.  55(1), s 371- 379 . doi: 10.3233/JAD-160461
  • Lee, Hyun-Wook; Osis, Gunars; Handlogten, Mary E.; Lamers, Wouter H.; Chaudhry, Farrukh Abbas; Verlander, Jill W. & Weiner, I. David (2016). Proximal tubule-specific glutamine synthetase deletion alters basal and acidosis-stimulated ammonia metabolism. American Journal of Physiology - Renal Physiology.  ISSN 0363-6127.  310(11), s F1229- F1242 . doi: 10.1152/ajprenal.00547.2015
  • Moen, Marivi Nabong; Fjær, Roar; Hamdani, El Hassan; Lærdahl, Jon Kristen; Menchini, Robin Johansen; Vigeland, Magnus Dehli; Sheng, Ying; Undlien, Dag Erik; Hassel, Bjørnar; Salih, MA; Khashab, HY; Selmer, Kaja Kristine & Chaudhry, Farrukh Abbas (2016). Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport. Brain.  ISSN 0006-8950.  139, s 3109- 3120 . doi: 10.1093/brain/aww244
  • Watne, Leiv Otto; Idland, Ane-Victoria; Fekkes, Durk; Ræder, Johan; Frihagen, Frede Jon; Ranhoff, Anette Hylen; Chaudhry, Farrukh Abbas; Engedal, Knut; Wyller, Torgeir Bruun & Hassel, Bjørnar (2016). Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity. BMC Geriatrics.  ISSN 1471-2318.  16(149) . doi: 10.1186/s12877-016-0324-0 Full text in Research Archive
  • Hu, Liyan; Ibrahim, Khalid; Stucki, Martin; Frapolli, Michele; Shahbeck, Noora; Chaudhry, Farrukh Abbas; Görg, Boris; Häussinger, Dieter; Penberthy, W. Todd; Ben-Omran, Tawfeg & Haberle, Johannes (2015). Secondary NAD+ deficiency in the inherited defect of glutamine synthetase. Journal of Inherited Metabolic Disease.  ISSN 0141-8955.  38(6), s 1075- 1083 . doi: 10.1007/s10545-015-9846-4
  • Soussi, Rabia; Boulland, Jean-Luc; Emilie, Bassot; Bras, Hélène; Coulon, Patrice; Chaudhry, Farrukh Abbas; Storm-Mathisen, Jon; Ferhat, Lotfi & Esclapez, Monique (2014). Reorganization of supramammillary–hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting. Brain Structure and Function.  ISSN 1863-2653.  220(4), s 2449- 2468 . doi: 10.1007/s00429-014-0800-2
  • Jenstad, Monica & Chaudhry, Farrukh Abbas (2013). The Amino Acid Transporters of the Glutamate/GABA-Glutamine Cycle and Their Impact on Insulin and Glucagon Secretion. Frontiers in Endocrinology.  ISSN 1664-2392.  4 . doi: 10.3389/fendo.2013.00199 Full text in Research Archive
  • Nissen-Meyer, Lise Sofie Haug & Chaudhry, Farrukh Abbas (2013). Protein kinase C phosphorylates the system N glutamine transporter SN1 (Slc38a3) and regulates its membrane trafficking and degradation. Frontiers in Endocrinology.  ISSN 1664-2392.  4, s 1- 7 . doi: 10.3389/fendo.2013.00138 Full text in Research Archive
  • Stensrud, Mats Julius; Chaudhry, Farrukh Abbas; Leergaard, Trygve Brauns; Bjaalie, Jan G. & Gundersen, Vidar (2013). Vesicular glutamate transporter-3 in the rodent brain: Vesicular colocalization with vesicular -aminobutyric acid transporter. Journal of Comparative Neurology.  ISSN 0021-9967.  521(13), s 3042- 3056 . doi: 10.1002/cne.23331
  • Antonucci, Flavia; Alpar, Alán; Kacza, Johannes; Caleo, Matteo; Verderio, Claudia; Giani, Alice; Martens, Henrik; Chaudhry, Farrukh Abbas; Allegra, Manuela; Grosche, Jens; Michalski, Dominik; Erck, Christian; Hoffmann, Anke; Harkany, Tibor; Matteoli, Michela & Härtig, Wolfgang (2012). Cracking Down on Inhibition: Selective Removal of GABAergic Interneurons from Hippocampal Networks. Journal of Neuroscience.  ISSN 0270-6474.  32(6), s 1989- 2001 . doi: 10.1523/JNEUROSCI.2720-11.2012
  • Boulland, Jean-Luc & Chaudhry, Farrukh Abbas (2012). Ontogenetic changes in the distribution of the vesicular GABA transporter VGAT correlate with the excitation/inhibition shift of GABA action. Neurochemistry International.  ISSN 0197-0186.  61(4), s 506- 516 . doi: 10.1016/j.neuint.2012.03.018
  • Haberle, Johannes; Shahbeck, Noora; Khalid, Ibrahim; Schmitt, Bernhard; Scheer, Ianina; O’Gorman, Ruth; Chaudhry, Farrukh Abbas & Ben-Omran, Tawfeg (2012). Glutamine supplementation in a child with inherited GS deficiency improves the clinical status and partially corrects the peripheral and central amino acid imbalance. Orphanet Journal of Rare Diseases.  ISSN 1750-1172.  7(48) . doi: 10.1186/1750-1172-7-48
  • Hamdani, El Hassan; Gudbrandsen, Marius; Bjørkmo, Mona & Chaudhry, Farrukh Abbas (2012). The system N transporter SN2 doubles as a transmitter precursor furnisher and a potential regulator of NMDA receptors. Glia.  ISSN 0894-1491.  60(11), s 1671- 1683 . doi: 10.1002/glia.22386
  • Oguchi, Tomohiro; Suzuki, Nobuyoshi; Hashimoto, Shigenari; Chaudhry, Gauhar Ayub; Chaudhry, Farrukh Abbas; Usami, Shin-ichi & Ottersen, Ole Petter (2012). Inner hair cells of mice express the glutamine transporter SAT1. Hearing Research.  ISSN 0378-5955.  292(1-2), s 59- 63 . doi: 10.1016/j.heares.2012.07.005
  • Ormel, Lasse; Stensrud, Mats Julius; Chaudhry, Farrukh Abbas & Gundersen, Vidar (2012). A distinct set of synaptic-like microvesicles in atroglial cells contain VGLUT3. Glia.  ISSN 0894-1491.  60(9), s 1289- 1300 . doi: 10.1002/glia.22348
  • Perez, Edgar L.; Lauritzen, Fredrik; Wang, Yue; Lee, Tih-Shih W.; Kang, Dewey; Zaveri, Hitten P.; Chaudhry, Farrukh Abbas; Ottersen, Ole Petter; Bergersen, Linda Hildegard & Eid, Tore (2012). Evidence for astrocytes as a potential source of the glutamate excess in temporal lobe epilepsy. Neurobiology of Disease.  ISSN 0969-9961.  47(3), s 331- 337 . doi: 10.1016/j.nbd.2012.05.010
  • Gammelsaeter, Runhild; Coppola, Thierry; Marcaggi, Païkan; Storm-Mathisen, Jon; Chaudhry, Farrukh Abbas; Attwell, David; Regazzi, Romano & Gundersen, Vidar (2011). A Role for Glutamate Transporters in the Regulation of Insulin Secretion. PLoS ONE.  ISSN 1932-6203.  6(8) . doi: 10.1371/journal.pone.0022960
  • Nissen-Meyer, Lise-Sofie; Popescu, Mark-Christian; Hamdani, El Hassan & Chaudhry, Farrukh Abbas (2011). Protein Kinase C-Mediated Phosphorylation of a Single Serine Residue on the Rat Glial Glutamine Transporter SN1 Governs Its Membrane Trafficking. Journal of Neuroscience.  ISSN 0270-6474.  31(17), s 6565- 6575 . doi: 10.1523/JNEUROSCI.3694-10.2011
  • Nemani, Venu; Lu, Weiping; Berge, Victoria; Nakamura, K; Onoa, Bibiana; Lee, Michael K; Chaudhry, Farrukh Abbas; Nicoll, Roger A & Edwards, Robert H. (2010). Increased Expression of alpha-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis. Neuron.  ISSN 0896-6273.  65(1), s 66- 79 . doi: 10.1016/j.neuron.2009.12.023
  • Blot, A; Billups, D; Bjørkmo, Mona; Quazi, Abrar Zaheer; Uwechue, NM; Chaudhry, Farrukh Abbas & Billups, B (2009). FUNCTIONAL EXPRESSION OF TWO SYSTEM A GLUTAMINE TRANSPORTER ISOFORMS IN RAT AUDITORY BRAINSTEM NEURONS. Neuroscience.  ISSN 0306-4522.  164(3), s 998- 1008 . doi: 10.1016/j.neuroscience.2009.09.015
  • Boulland, Jean-Luc; Jenstad, Monica; Boekel, AJ; Wouterlood, FG; Edwards, RH; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2009). Vesicular Glutamate and GABA Transporters Sort to Distinct Sets of Vesicles in a Population of Presynaptic Terminals. Cerebral Cortex.  ISSN 1047-3211.  19(1), s 241- 248 . doi: 10.1093/cercor/bhn077
  • Gammelsaeter, Runhild; Jenstad, Monica; Bredahl, May Kristin Lyamouri; Gundersen, Vidar & Chaudhry, Farrukh Abbas (2009). Complementary expression of SN1 and SAT2 in the islets of Langerhans suggests concerted action of glutamine transport in the regulation of insulin secretion. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  381(3), s 378- 382 . doi: 10.1016/j.bbrc.2009.02.062
  • Jenstad, Monica; Quazi, Abrar Zaheer; Zilberter, M; Haglerød, Camilla Margrete; Berghuis, P; Saddique, Navida; Goiny, Michel; Buntup, Doungjai; Davanger, Svend; Haug, Finn-Mogens Smejda; Barnes, CA; McNaughton, BL; Ottersen, Ole Petter; Storm-Mathisen, Jon; Harkany, T & Chaudhry, Farrukh Abbas (2009). System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signalling by glutamate. Cerebral Cortex.  ISSN 1047-3211.  19(5), s 1092- 1106 . doi: 10.1093/cercor/bhn151
  • Jenstad, Monica; Quazi, AZ; Haglerød, C.; Saddique, Navida; Buntup, D; Ottersen, OP; Davanger, Svend; Haug, FMS; Barnes, CA; McNaughton, BL; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2008). Replenishment of glutamate neurotransmitter pools in excitatory neurons requires glutamine uptake by system A transporter SAT2. Cerebral Cortex.  ISSN 1047-3211.
  • Boulland, Jean-Luc; Jenstad, Monica; Wouterlood, FG; Edwards, RH; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2008). Vesicular glutamate and GABA transporters are expressed on distinct subsets of synaptic vesicles at a synapse. Cerebral Cortex.  ISSN 1047-3211.
  • Buntup, D; Skare, Øivind; Solbu, Tom Tallak; Chaudhry, Farrukh Abbas; Storm-Mathisen, Jon & Thangnipon, W (2008). beta-amyloid 25-35 peptide reduces the expression of glutamine transporter SAT1 in cultured cortical neurons. Neurochemical Research.  ISSN 0364-3190.  33(2), s 248- 256 . doi: 10.1007/s11064-007-9527-2
  • Chaudhry, Farrukh Abbas; Boulland, Jean-Luc; Jenstad, Monica & Bredahl, May Kristin Lyamouri (2008). Pharmacology of neurotransmitter transport into secretory vesicles. Handbook of Experimental Pharmacology.  ISSN 0171-2004.  184, s 77- 106
  • Chaudhry, Farrukh Abbas; Edwards, RH & Fonnum, Frode (2008). Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substances. Annual Review of Pharmacology and Toxicology.  ISSN 0362-1642.  48 . doi: 10.1146/annurev.pharmtox.46.120604.141146
  • Martens, H; Weston, MC; Boulland, Jean-Luc; Harkany, T; Grosche, J.; Kacza, J; Hoffmann, A; Matteoli, M; Takamori, S; Chaudhry, Farrukh Abbas; Erck, C; Gronborg, M; Jahn, R & Hartig, W (2008). Unique luminal localization of VGAT carboxy-terminus allows for selective labelling of active cortical GABAergic synapses. Journal of Neuroscience.  ISSN 0270-6474.  3(28), s 13125- 13131
  • Boulland, Jean-Luc; Ferhat, L; Solbu, TT; Ferrand, N; Chaudhry, Farrukh Abbas; Storm-Mathisen, Jon & Esclapez, M (2007). Changes in vesicular transporters for gamma-aminobutyric acid and glutamate reveal vulnerability and reorganization of hippocampal neurons following pilocarpine-induced seizures. Journal of Comparative Neurology.  ISSN 0021-9967.  503, s 466- 485 . doi: 10.1002/cne.21384
  • Leibovici, A; Rossignol, C; Montrowl, JA; Erickson, JD; Varoqui, H; Watanabe, M; Chaudhry, Farrukh Abbas; Bredahl, May Kristin Lyamouri; Anderson, KJ & Weiss, MD (2007). The effects of hypoxia-ischemia on neutral amino acid transporters in the developing rat brain. Developmental Neuroscience.  ISSN 0378-5866.  29, s 268- 274 . doi: 10.1159/000097410
  • Larsen, Kristin E.; Schmitz, Yvonne; Troyer, Matthew D.; Mosharov, Eugene; Dietrich, Paula; Quazi, Abrar Zaheer; Savalle, Magali; Nemani, Venu; Chaudhry, Farrukh Abbas; Edwards, Robert H.; Stefanis, Leonidas & Sulzer, David (2006). alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis. Journal of Neuroscience.  ISSN 0270-6474.  26, s 11915- 11922
  • Martin-Ibanez, R; Jenstad, Monica; Berghuis, P; Edwards, RH; Hioki, H; Kaneko, T; Mulder, J; Canals, JM; Ernfors, P; Chaudhry, Farrukh Abbas & Harkany, T (2006). Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra. European Journal of Neuroscience.  ISSN 0953-816X.  23
  • Persson, S; Boulland, Jean-Luc; Aspling, M; Larsson, M; Fremeau, RT; Edwards, RH; Storm-Mathisen, Jon; Chaudhry, Farrukh Abbas & Broman, J (2006). Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract. Journal of Comparative Neurology.  ISSN 0021-9967.  497
  • Solbu, Tom Tallak & Chaudhry, Farrukh Abbas (2005). Glutamin-transportrers funksjoner i fysiologiske prosesser og i patologi. NBS-nytt.  ISSN 0801-3535.  (1), s 6- 8
  • Solbu, Tom Tallak; Boulland, Jean-Luc; Zahid, W; Bredahl, May Kristin Lyamouri; Amiry-Moghaddam, Mahmood Reza; Storm-Mathisen, Jon; Roberg, Bjørg Åse & Chaudhry, Farrukh Abbas (2005). Induction and targeting of the glutamine transporter SN1 to the basolateral membranes of cortical kidney tubule cells during chronic metabolic acidosis suggest a role in pH regulation. Journal of the American Society of Nephrology.  ISSN 1046-6673.  16
  • Boulland, Jean-Luc; Qureshi, T.; Seal, R; Rafiki, A; Gundersen, Vidar; Bergersen, Linda Hildegard; Fremeau, R.T Jr; Edwards, RH; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2004). Expression of the vesicular glutamate transporters during development indicates the widespread co-release of multiple neurotransmitters. Journal of Comparative Neurology.  ISSN 0021-9967.  480(3), s 264- 280
  • Fremeau, RT; Kam, K; Qureshi, T; Johnson, J; Copenhagen, DR; Storm-Mathisen, Jon; Chaudhry, Farrukh Abbas; Nicoll, RA & Edwards, RH (2004). Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science.  ISSN 0036-8075.  304(5678), s 1815- 1819
  • Harkany, T; Holmgren, C; Hartig, W; Qureshi, T; Chaudhry, Farrukh Abbas; Storm-Mathisen, Jon; Dobszay, MB; Berghuis, P; Schulte, G; Sousa, KM; Fremeau, RT; Edwards, RH; Mackie, K; Ernfors, P & Zilberter, Y (2004). Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: Involvement of vesicular glutamate transporter 3. Journal of Neuroscience.  ISSN 0270-6474.  24(21), s 4978- 4988
  • Maghazachi, Azzam; Knudsen, Eirunn; Jin, Yixin; Jenstad, Monica & Chaudhry, Farrukh Abbas (2004). D-galactosyl-b1-1' sphingosine and D-glucosyl-b1-1' sphingosine induce human natural killer cell apoptosis. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  320, s 810- 815
  • Boulland, JL; Rafiki, A; Levy, Line Margrete; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2003). Highly differential expression of SN1, a bidirectional glutamine transporter, in astroglia and endothelium in the developing rat brain. Glia.  ISSN 0894-1491.  41, s 260- 275
  • Boulland, Jean-Luc; Osen, Kirsten K.; Levy, Line Margrete; Danbolt, Niels Christian; Edwards, R. H.; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2002). Cell-specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle. European Journal of Neuroscience.  ISSN 0953-816X.  15(10), s 1615- 1631
  • Bröer, A.; Albers, A.; Setiawan, I.; Edwards, R. H.; Chaudhry, Farrukh Abbas; Lang, F.; Wagner, C.A. & Bröer, S. (2002). Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions. Journal of Physiology.  ISSN 0022-3751.  539, s 3- 14
  • Chaudhry, Farrukh Abbas; Reimer, R.J. & Edwards, R. H. (2002). The glutamine commute: take the N and transfer to the A line. Journal of Cell Biology.  ISSN 0021-9525.  157, s 349- 355
  • Chaudhry, Farrukh Abbas; Schmitz, D.; Reimer, R.J.; Larsson, P.; Gray, A.T.; Nicoll, R.; Kavanaugh, M. & Edwards, R. H. (2002). Glutamine uptake by neurons: interaction of protons with system A transporters. Journal of Neuroscience.  ISSN 0270-6474.  22, s 62- 72
  • Fremeau, R.T Jr; Burman, J.; Qureshi, T.; Tran, C. H.; Proctor, J.; Johnson, J.; Zhang, I.; Sulzer, D.; Copenhagen, D.R.; Storm-Mathisen, Jon; Reimer, R.J.; Chaudhry, Farrukh Abbas & Edwards, R. H. (2002). The distribution of a vesicular glutamate transporter suggests novel modes of signalling by glutamate. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  99, s 14488- 14493
  • Chaudhry, Farrukh Abbas; Krizaj, D.; Larsen, P; Reimer, R.J.; Storm-Mathisen, Jon; Copenhagen, D.R.; Kavanaugh, M. & Edwards, RH (2001). Coupled and uncoupled proton movement regulates amino acid transport by System N. EMBO Journal.  ISSN 0261-4189.  20(24), s 7041- 7051
  • Allen, P. B.; Hvalby, Øyvind Christian; Jensen, Vidar; Errington, M. L.; Ramsay, M.; Chaudhry, Farrukh Abbas; Bliss, T. V. P.; Storm-Mathisen, Jon; Morris, Richard G.M.; Andersen, Per & Greengard, Paul (2000). Protein phosphatase-1 regulation in the induction of long-term potentiation: heterogeneous molecular mechanisms. Journal of Neuroscience.  ISSN 0270-6474.  20, s 4537- 3543
  • Chaudhry, Farrukh Abbas; Reimer, R.J.; Krizaj, D.; Barber, R.; Storm-Mathisen, Jon; Copenhagen, D.R. & Edwards, R. H. (1999). Molecular analysis of System N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell.  ISSN 0092-8674.  99(7), s 769- 780
  • Masson, J.; Riad, M.; Chaudhry, Farrukh Abbas; Darmon, M.; Aidouni, Z.; Conrath, M.; Giros, B.; Hamon, M.; Storm-Mathisen, Jon; Descarries, L. & Mestikawy, S. El (1999). Unexpected localization of the Na<sup>+</sup>/CI<sup>-</sup>-dependent-like orphan transporter, Rxt1, on synaptic vesicles in the rat central nervous system. European Journal of Neuroscience.  ISSN 0953-816X.  11, s 1349- 1361
  • Chaudhry, Farrukh Abbas; Reimer, R.J.; Bellocchio, E. E.; Danbolt, Niels Christian; Osen, Kirsten K.; Edwards, R. H. & Storm-Mathisen, Jon (1998). The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sets of glycinergic as well as GABAergic neurons. Journal of Neuroscience.  ISSN 0270-6474.  18, s 9733- 9750
  • Danbolt, Niels Christian; Chaudhry, Farrukh Abbas; Dehnes, Yvette; Lehre, Knut Petter; Levy, Line Margrete; Ullensvang, Kyrre & Storm-Mathisen, Jon (1998). Properties and localization of glutamate transporters, In Ole Petter Ottersen; Iver Arne Langmoen & Leif Gjerstad (ed.),  Prog Brain Res.   s 23 - 43
  • Danbolt, Niels Christian; Chaudhry, Farrukh Abbas; Dehnes, Yvette; Lehre, Knut Petter; Levy, Line Margrete; Ullensvang, Kyrre & Storm-Mathisen, Jon (1998). Properties and localization of glutamate transporters. Progress in Brain Research.  ISSN 0079-6123.  116, s 23- 43
  • Danbolt, Niels Christian; Lehre, Knut Petter; Dehnes, Yvette; Chaudhry, Farrukh Abbas & Levy, Line Margrete (1998). Localization of transporters using transporter-specific antibodies. Methods in Enzymology.  ISSN 0076-6879.  296, s 388- 407
  • Danbolt, Niels Christian; Lehre, Knut Petter; Dehnes, Yvette; Chaudhry, Farrukh Abbas & Levy, Line Margrete (1998). Localization of transporters using transporter-specific antibodies. Methods in Enzymology.  ISSN 0076-6879.  296, s 388- 407
  • Dehnes, Yvette; Chaudhry, Farrukh Abbas; Ullensvang, Kyrre; Lehre, Knut Petter; Storm-Mathisen, Jon & Danbolt, Niels Christian (1998). The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia. Journal of Neuroscience.  ISSN 0270-6474.  18, s 3606- 3619

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  • Chaudhry, Farrukh Abbas; Knutsen, Leif; Kohn, Leoni Abrahamsen & Kirschner, Rolf Steinar (2016). Re: Omskjæring av gutter. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  136(2), s 106
  • Chaudhry, Farrukh Abbas (2013). Nervesystemet, I: Gunnar Nicolaysen & Per Holck (red.),  Kroppens funksjon og oppbygning.  Gyldendal Akademisk.  ISBN 9788205323629.  Kapittel 2.  s 55 - 94
  • Chaudhry, Farrukh Abbas; Nissen-Meyer, Lise Sofie Haug; Popescu, Mark-Christian; Bjørkmo, Mona; Gudbrandsen, Marius & Hamdani, El Hassan (2013). SN2 (Slc38a5) resembles SN1 (Slc38a3) in electroneutral transport but partly differ in functional roles. Journal of Neurochemistry.  ISSN 0022-3042.  125, s 153- 153
  • Chaudhry, Farrukh Abbas (2012). (Patho-)functional roles of glutamine transporters in neurotransmission, insulin secretion and pH regulation.
  • Chaudhry, Farrukh Abbas (2012). Glutamate and GABA recycling through glutamine – what is the significance.
  • Chaudhry, Farrukh Abbas (2012). Glutamintilførsel ved medfødt glutaminesvikt. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  18, s 132- 132
  • Haberle, Johannes; Ibrahim, Khalid; Hu, L.; Frapolli, Michele; Stucki, Martin; Scheer, Ianina; O'Gorman, Ruth; Chaudhry, Farrukh Abbas & Ben-Omran, Tawfeg (2012). Pathofunctional roles of glutamine transporters in neurotransmission, insulin secretion and pH regulation. Molecular Genetics and Metabolism.  ISSN 1096-7192.  105, s 283
  • Haberle, Johannes; Ibrahim, Khalid; Shahbeck, Noora; Hu, Liyan; Frapolli, Michele; Stucki, Martin; Scheer, Ianina; O'Gorman, Ruth; Chaudhry, Farrukh Abbas & Ben-Omran, Tawfeg (2012). Glutamine synthetase deficiency: An emerging disorder of nitrogen metabolism. Molecular Genetics and Metabolism.  ISSN 1096-7192.  105(3), s 283- 283
  • Antonucci, F; Alpár, A; Kacza, J; Caleo, M; Verderio, C; Giani, A; Martens, H; Chaudhry, Farrukh Abbas; Allegra, M.; Grosche, J.; Michalski, D; Erck, C; Hoffmann, A; Harkany, T & Matteoli, M (2011). Cracking Down on Inhibition: Selective Removal of GABAergic Interneurons from Hippocampal Networks. Journal of Neuroscience.  ISSN 0270-6474.  32(6), s 1989- 2001
  • Hossain, Shaikh Abu; Chaudhry, Farrukh Abbas; Zahedi, Kamyar; Siddiqui, Faraaz & Amlal, Hassane (2011). Cellular and molecular basis of increased ammoniagenesis in potassium deprivation. American Journal of Physiology - Renal Physiology.  ISSN 0363-6127.  301(5), s 969- 978 . doi: 10.1152/ajprenal.00010.2011
  • Solbu, Tom Tallak; Bjørkmo, Mona; Berghuis, P; Harkany, T & Chaudhry, Farrukh Abbas (2009). SAT1, a glutamine transporter, is preferentially expressed in GABAergic neurons. Frontiers in Neuroanatomy.  ISSN 1662-5129. . doi: 10.3389/neuro.05.033.2010
  • Boulland, Jean-Luc; Jenstad, Monica; Boekel, AJ; Wouterlood, FG; Edwards, RH; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2008). VGLUT2 and VGAT are targeted to different subsets of vesicles within a single terminal.
  • Buntup, D; Thangnipon, W; Solbu, Tom Tallak; Chaudhry, Farrukh Abbas & Storm-Mathisen, Jon (2008). Effects of -amyloid25-35 on the expression of glutamine transporters and vesicular glutamate transporters in rat cortical cell cultures. Journal of Neurochemistry.  ISSN 0022-3042.  s 357- 357
  • Chaudhry, Farrukh Abbas (2008). Neurotransmitter transport.
  • Chaudhry, Farrukh Abbas; Jenstad, Monica; Boekel, AJ; Wouterlood, FG; Edwards, R. H.; Storm-Mathisen, Jon & Boulland, Jean-Luc (2008). 331.2. VGLUT2 and VGAT reside on different subpopulations of vesicles suggesting differential release of glutamate and GABA from a single nerve terminal.
  • Chaudhry, Farrukh Abbas; Fonnum, F & Edwards, RH (2007). Vesicular neurotransmitter transporters as targets for psychostimulants and novel therapeutic agents. Annual Review of Pharmacology and Toxicology.  ISSN 0362-1642.  48, s 277- 301
  • Bredahl, May Kristin Lyamouri; Solbu, Tom Tallak; Boulland, Jean-Luc; Zahid, W; Storm-Mathisen, J & Chaudhry, Farrukh Abbas (2005). SN1, a neutral amino acid transporter, is regulated in the kidney during chronic metabolic acidosis by stabilization of the mRNA. Journal of Neurochemistry.  ISSN 0022-3042.  s 357- 357
  • Chaudhry, Farrukh Abbas (2005). Glutamate in CNS metabolism and neurotransmission: interactions at the inter- and intracellular level.
  • Chaudhry, Farrukh Abbas (2005). Membrane transporters: bridging basic and applied sciences.
  • Chaudhry, Farrukh Abbas (2005). Molecular Approaches to Membrane Transport.
  • Chaudhry, Farrukh Abbas (2005). Neurocircuits and the synapse.
  • Chaudhry, Farrukh Abbas (2005). New perspectives in neurotransmitter transporter biology.
  • Chaudhry, Farrukh Abbas (2005). Perspectives in Transport Biology.
  • Faroqui, S; Chaudhry, Farrukh Abbas & Amlal, H (2005). Coordinated upregulation of Na+-glutamine cotransporter (SN1) and ammoniagenesis enzymes in the cortex of potassium-deprived rats.
  • Gundersen, V; Gammelsaeter, R; Chaudhry, Farrukh Abbas; Danbolt, NC; Regazzi, R & Storm-Mathisen, J (2005). Novel roles of glutamate transporters in the regulation of insulin secretion.
  • Jenstad, M; Quazi, Abrar Zaheer; Barnes, CA; McNaughton, BL; Storm-Mathisen, J & Chaudhry, Farrukh Abbas (2005). Increased de novo synthesis of glutamate from glutamine upon high frequency stimulation of SAT2 expressing neurons.
  • Quazi, Abrar Zaheer; Jenstad, Monica; Haglerød, Camilla Margrete; Saddique, N; Ottersen, Ole Petter; Davanger, Svend; Haug, Finn-Mogens Smejda; Barnes, CA; McNaughton, BL; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2005). Glutamine shuttling by the system N and system A transporters is important for the regeneration of the neurotransmitter glutamate during high frequency firing.
  • Solbu, Tom Tallak; Boulland, Jean-Luc; Bredahl, May Kristin Lyamouri; Zahid, W; Kongsvik, Thomas Lasker; Storm-Mathisen, J & Chaudhry, Farrukh Abbas (2005). SN1, a neutral amino acid transporter, is upregulated during chronic metabolic acidosis by stabilization of the mRNA.
  • Solbu, Tom Tallak; Boulland, Jean-Luc; Bredahl, May Kristin Lyamouri; Zahid, W; Kongsvik, Thomas Lasker; Storm-Mathisen, J & Chaudhry, Farrukh Abbas (2005). Stabilization of AU-RICH elements in 3'UTR upregulates the neutral amino acid transporter SN1 during chronic metabolic acidosis.
  • Chaudhry, Farrukh Abbas (2004). Characterization of transporter proteins involved in the recycling of the neurotransmitters glutamate and GABA. Journal of Neurochemistry.  ISSN 0022-3042.  90, s 132- 132
  • Chaudhry, Farrukh Abbas; Boulland, Jean-Luc; Jenstad, M; Bredahl, May Kristin Lyamouri & Edwards, RH (2004). Pharmacology of neurotransmitter transport into secretory vesicles. Handbook of Experimental Pharmacology.  ISSN 0171-2004.  184, s 77- 106
  • Gammelsæter, Runhild; Gundersen, Vidar; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2003). Expression of VGLUT2 and VGLUT3 in pancreatic neuroendocrine cells: preserved after transplantation of islets of Langerhans to kidney.
  • Solbu, Tom Tallak; Zahid, W.; Boulland, JL; Qureshi, T.; Storm-Mathisen, Jon & Chaudhry, Farrukh Abbas (2003). Targeting of the proton-coupled glutamine transporter, SN1, suggests roles in synaptic functions and pH. Glia.  ISSN 0894-1491.  s 32- 32
  • Chaudhry, Farrukh Abbas; Boulland, Jean-Luc; Qureshi, T; Solbu, Tom Tallak; Jenstad, Monica; Kanstad, Kristin; Zahid, W; Haglerød, Camilla Margrete; Edwards, RH & Storm-Mathisen, Jon (2003). Glutamine and vesicular glutamate transporters involved in the glutamine-glutamate/GABA cycle. Journal of Neurochemistry.  ISSN 0022-3042.  87, s 3- 3
  • Chaudhry, Farrukh Abbas; Boulland, Jean-Luc; Solbu, Tom Tallak; Jenstad, Monica; Haglerød, Camilla Margrete; Zahid, W & Storm-Mathisen, Jon (2003). Glutamine transporters involved in the glutamine-glutamate/GABA cycle. Journal of Neurochemistry.  ISSN 0022-3042.  87, s 4- 4
  • Chaudhry, Farrukh Abbas (2002). Molecular mechanisms of glutamine transfer between cells.
  • Chaudhry, Farrukh Abbas (2002). Vesicular glutamate transporters.
  • Solbu, Tom Tallak; Jenstad, Monica; Etemad, K. K.; Zahid, W.; Boulland, Jean-Luc; Storm-Mathisen, Jon; Edwards, R. H. & Chaudhry, Farrukh Abbas (2002). Glutamine transporters involved in the glutamine-glutamate/GABA cycle.
  • Boulland, Jean-Luc; Rafiki, Mina; Beckstrøm, Henning; Levy, Line Margrete; Osen, Kirsten K.; Danbolt, Niels Christian; Storm-Mathisen, Jon; Edwards, R. H. & Chaudhry, Farrukh Abbas (2001). The glutamine transporter protein SN1: postnatal development and localization in the adult rat brain.
  • Danbolt, Niels Christian; Beckstrøm, Henning; Chaudhry, Farrukh Abbas; Dehnes, Yvette; Furness, David; Haugeto, Øyvind; Lehre, Knut Petter; Levy, Line Margrete; Ullensvang, Kyrre & Storm-Mathisen, Jon (2001). Roles of glutamate transporters in the brain.
  • Chaudhry, Farrukh Abbas; Reimer, R.J.; Krazaj, D.; Storm-Mathisen, Jon; Copenhagen, D.R. & Edwards, R. H. (1999). A novel protein related to the vesicular GABA transporter.
  • Lehre, Knut Petter; Chaudhry, Farrukh Abbas; Dehnes, Yvette; Ullensvang, Kyrre; Ottersen, Ole Petter; Storm-Mathisen, Jon & Danbolt, Niels Christian (1999). Localization of glutamate transporters and quantification in absolute terms.
  • Dehnes, Yvette; Chaudhry, Farrukh Abbas; Ullensvang, Kyrre; Lehre, Knut Petter; Storm-Mathisen, Jon & Danbolt, Niels Christian (1998). The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: A glutamate-gated chloride channel concentrated in the dendritic membrane facing astroglia.

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Published Aug. 15, 2013 12:44 PM - Last modified Apr. 10, 2015 3:30 PM