Philippe Collas

Image of Philippe Collas
Norwegian version of this page
Phone +47-22851066
Room 2250
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1110 Blindern 0317 OSLO

Academic interests

  • Reprogramming of nuclear function
  • Epigenetic determination of lineage commitment in mesenchymal stem cells
  • Organization and dynamics of the cell nucleus

Courses taught

  • MF9390: ”Epigenetics, Development and Disease”

Background

1991:  Ph.D., University of Massachusetts, Amherst, MA, USA.

Area: embryo cloning

URL: www.collaslab.com

Curriculum Vitae (pdf)

Awards

  • Elected member of the Norwegian Academy of Sciences

Positions held

  • 1991 1993: Research Scientist, Genmark, Inc., Salt Lake City, UT, USA
  • 1992 2004: Adjunct Professor, University of Massachusetts, Amherst, MA, USA
  • 1993 1995: Research Associate, Dept. of Biology, Amherst College, Amherst, MA, USA
  • 1995-1998: Scientist, Dept. of Biochemistry, Norwegian College of Veterinary Medicine, Oslo
  • 1999-2003: Senior Research Scientist, Institute of Medical Biochemistry, University of Oslo; Fellow of the Norwegian Cancer Society 
  • 2003-present: Professor, Institute of Basic Medical Sciences, Dep. of Biochemistry, University of Oslo
  • 2009-present: Senior Scientist II, Rikshospitalet University Hospital, Oslo
Tags: Biochemistry, Life science, Stem cells

Publications

  • Briand, Nolwenn & Collas, Philippe (2018). Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation. Nucleus.  ISSN 1949-1034.  9(1), s 216- 226 . doi: 10.1080/19491034.2018.1449498
  • Briand, Nolwenn; Guénantin, Anne-Claire; Jeziorowska, Dorota; Shah, Akshay; Mantecon, Matthieu; Capel, Emilie; Garcia, Maria; Oldenburg, Anja; Paulsen, Jonas; Hulot, Jean-Sébastien; Vigouroux, Corinne & Collas, Philippe (2018). The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks. Human Molecular Genetics.  ISSN 0964-6906.  27(8), s 1447- 1459 . doi: 10.1093/hmg/ddy055
  • La Cour Poulsen, Lars; Edelmann, Reidunn Jetne; Krüger, Stig; Diéguez-Hurtado, Rodrigo; Shah, Akshay; Stav-Noraas, Tor Espen; Renzi, Anastasia; Szymanska, Monika; Wang, Junbai; Ehling, Manuel; Benedito, Rui; Kasprzycka, Monika; Bækkevold, Espen Sønderaal; Sundnes, Olav; Midwood, Kim S.; Scott, Helge; Collas, Philippe; Siebel, Christian W.; Adams, Ralf H.; Haraldsen, Guttorm; Sundlisæter, Eirik & Hol, Johanna (2018). Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers. Arteriosclerosis, Thrombosis and Vascular Biology.  ISSN 1079-5642.  38(4), s 854- 869 . doi: 10.1161/ATVBAHA.117.310388
  • Paulsen, Jonas; Liyakat Ali, Tharvesh Moideen & Collas, Philippe (2018). Computational 3D genome modeling using Chrom3D. Nature Protocols.  ISSN 1754-2189.  13(5), s 1137- 1152 . doi: 10.1038/nprot.2018.009
  • Udugama, Maheshi; Sanij, Elaine; Voon, Hsiao P.J.; Son, Jinbae; Hii, Linda; Henson, Jeremy D.; Lyn Chan, F.; Chang, Fiona T.M.; Liu, Yumei; Pearson, Richard B.; Kalitsis, Paul; Mann, Jeffrey R.; Collas, Philippe; Hannan, Ross D. & Wong, Lee H. (2018). Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  115(18), s 4737- 4742 . doi: 10.1073/pnas.1720391115
  • Delbarre, Erwan; Ivanauskiene, Kristina; Spirkoski, Jane; Shah, Akshay; Vekterud, Kristin; Moskaug, Jan Øivind; Bøe, Stig Ove; Wong, Lee H.; Küntziger, Thomas M. & Collas, Philippe (2017). PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX. Genome Research.  ISSN 1088-9051.  27(6), s 913- 921 . doi: 10.1101/gr.215830.116 Full text in Research Archive.
  • Garcia-Nieto, Pablo E; Schwartz, Erin K; King, Devin A; Paulsen, Jonas; Collas, Philippe; Herrera, Rafael E & Morrison, Ashby J (2017). Carcinogen susceptibility is regulated by genome architecture and predicts cancer mutagenesis. EMBO Journal.  ISSN 0261-4189.  36(19), s 2829- 2843 . doi: 10.15252/embj.201796717
  • Guénantin, Anne-Claire; Briand, Nolwenn; Capel, Emilie; Dumont, Florent; Morichon, Romain; Provost, Claire; Stillitano, Francesca; Jeziorowska, Dorota; Siffroi, Jean-Pierre; Hajjar, Roger J.; Fève, Bruno; Hulot, Jean-Sébastien; Collas, Philippe; Capeau, Jacqueline & Vigouroux, Corinne (2017). Functional human beige adipocytes from induced pluripotent stem cells. Diabetes.  ISSN 0012-1797.  66(6), s 1470- 1478 . doi: 10.2337/db16-1107
  • Holm, Kristine Lillebø; Syljuåsen, Randi G.; Hasvold, Grete; Alsøe, Lene; Nilsen, Hilde Loge; Ivanauskiene, Kristina; Collas, Philippe; Shaposhnikov, Sergey; Collins, Andrew Richard; Indrevær, Randi Larsen; Aukrust, Pål; Fevang, Børre & Blomhoff, Heidi Kiil (2017). TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency. PLoS ONE.  ISSN 1932-6203.  12(10) . doi: 10.1371/journal.pone.0185708 Full text in Research Archive.
  • Lopez Soop, Graciela; Rønningen, Torunn; Rogala, Agnieszka; Richartz, Nina; Blomhoff, Heidi Kiil; Thiede, Bernd; Collas, Philippe & Küntziger, Thomas M. (2017). AKAP95 interacts with nucleoporin TPR in mitosis and is important for the spindle assembly checkpoint. Cell Cycle.  ISSN 1538-4101.  16(10), s 947- 956 . doi: 10.1080/15384101.2017.1310350 Full text in Research Archive.

View all works in Cristin

Published Apr. 13, 2011 2:41 PM - Last modified Aug. 2, 2012 12:22 PM