Tore Jahnsen

Image of Tore Jahnsen
Norwegian version of this page
Phone +47-22851061
Room 3169
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1112 Blindern 0317 OSLO

Academic interests

  • Structure, function, regulation and subcellular localisation of cAMP- dependent protein kinases
  • Phylogenetic analysis of the catalytic subunit of cAMP-dependent protein kinase
  • Heterogeneity in the human PKA Cα and Cβ genes – functional consequences and opportunities for novel diagnostics and therapeutics
  • Human sperm motility and metasbolism

Courses taught

  • Cell biology, molecular biology and nucleotide metabolism for medical students

Background

Education

  • 1983  Dr.med. (Doctoral thesis, Ph.D.), University of Oslo. "Regulation of   gonadotropin responsive adenylyl cyclases in rat testes"
  • 1982  Cand.med. (M.D.). The Faculty of Medicine of the University of Oslo

Present position

  • 1992 – to present: Professor, Department of Biochemistry, University of Oslo, Norway

Awards

  • 1991 Anders Jahres Award (for scientists less than 40 years old)

Positions held

  • Teaching leader, Department of Biochemistry, University of Oslo, Norway
  • Board member Rheumatech AS and Spermatech AS

Collaboration

Collaboration with professor Bjørn S. Skålhegg at the Department of Nutrition, University of Oslo. We have a research group presently consisting of 9 persons. These include technicians, master students, medical students, Ph.D.- students, and post-docs.

Tags: Protein kinases, Contraceptives, cAMP, Sperm motility

Publications

  • Søberg, Kristoffer; Jahnsen, Tore; Rognes, Torbjørn; Skålhegg, Bjørn Steen & Lærdahl, Jon Kristen (2013). Evolutionary Paths of the cAMP-Dependent Protein Kinase (PKA) Catalytic Subunits. PLoS ONE.  ISSN 1932-6203.  8(4) . doi: 10.1371/journal.pone.0060935 Full text in Research Archive.
  • Søberg, Kristoffer; Larsen, Anja C V; Diskar, Mandy; Backe, Paul Hoff; Bjørås, Magnar; Jahnsen, Tore; Lærdahl, Jon Kristen; Rognes, Torbjørn; Herberg, Friedrich W. & Skålhegg, Bjørn Steen (2012). Identification and Characterization of Novel Mutations in the Human Gene Encoding the Catalytic Subunit Calpha of Protein Kinase A (PKA). PLoS ONE.  ISSN 1932-6203.  7(4) . doi: 10.1371/journal.pone.0034838 Full text in Research Archive.
  • Hereng, Tuva Holt; Elgstøen, Katja B. Prestø; Cederkvist, Fritjof Henning; Eide, Lars; Jahnsen, Tore; Skålhegg, Bjørn Steen & Rosendal, K.R (2011). Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa. Human Reproduction.  ISSN 0268-1161.  26(12), s 3249- 3263 . doi: 10.1093/humrep/der317
  • Kvissel, Anne Katrine; Ørstavik, Sigurd; Eikvar, Sissel; Brede, Gaute; Jahnsen, Tore; Collas, Philippe; Akusjarvi, G & Skålhegg, Bjørn Steen (2007). Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing. PMID: 17594903 [PubMed - in process]. Experimental Cell Research.  ISSN 0014-4827.  313, s 2795- 2809 . doi: 10.1016/j.yexcr.2007.05.014
  • Orstavik, Sigurd; Funderud, Ane; Hafte, Tolesa Tilahun; Eikvar, Sissel; Jahnsen, Tore & Skålhegg, Bjørn Steen (2005). Identification and characterization of novel PKA holoenzymes in human T lymphocytes. The FEBS Journal.  ISSN 1742-464X.  272, s 1559- 1567
  • Kvissel, Anne Katrine; Ørstavik, Sigurd; Øistad, P; Rootwelt, Terje; Jahnsen, Tore & Skålhegg, Bjørn Steen (2004). Induction of Cbeta splice variants and formation of novel forms of protein kinase A type II holoenzymes during retinoic acid-induced differentiation of human NT2 cells. Cellular Signalling.  ISSN 0898-6568.  16(5), s 577- 587 Show summary
  • Eide, Turid; Tasken, Kristin Austlid; Carlson, C.; Williams, G.; Jahnsen, Tore; Tasken, Kjetil & Collas, Philippe (2003). Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication.. Journal of Biological Chemistry.  ISSN 0021-9258.  278(29), s 26750- 26756

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  • Søberg, Kristoffer; Skålhegg, Bjørn Steen & Jahnsen, Tore (2017). On the evolution and function of the catalytic subunits of protein kinase A (PKA).
  • Kvissel, Anne Katrine; Orstavik, S; Eikvar, Sissel; Øistad, Pia Madeleine; Punga, T; Jahnsen, Tore; Collas, Philippe; Akusjarvi, G & Skalhegg, BS (2004). Co-localization and in vitro phosphorylation of splicing factors by cAMP-dependent protein kinase. The FASEB Journal.  ISSN 0892-6638.  18, s C259- C259
  • Eide, Turid; Jahnsen, Tore & Tasken, Kjetil (2002). Diverse functions of the A-Kinase Anchoring Protein AKAP95 and the AKAP95 Homologous Protein HA95 in Nuclear dynamics.

View all works in Cristin

Published Apr. 13, 2011 2:41 PM - Last modified Aug. 2, 2012 12:41 PM

Research groups