Challenges

  • Little is known about the magnitude of the bias caused by lack of reproducibility in categorical variables with multiple levels of exposure. Estimation of misclassification probabilities and bias in relative risk estimates of categorical variables is a challenge for future research.
  • Modern medical studies collect enormous amounts of data and optimal use of statistical methods is a challenge.
  • Obesity is a risk factor of cancer, but will weight reduction in obese individuals reduce their risk of cancer? 
  • Solar and artificial UV exposure are carcinogenic (skin cancer), but are also sources of vitamin D which is essential to avoid bone diseases. Several studies have suggested beneficial roles of vitamin D and solar and artificial UV exposure for many diseases including cancer and cardiovascular disease. This complicates the public health message and more knowledge is warranted.
  • Individuals typically use sunscreens to stay longer in the sun, thus sunscreen use may increase the risk of cutaneous malignant melanoma. We need more knowledge about who uses sunscreens and the association between sunscreens and melanoma risk. 
  • Nausea alone or nausea and vomiting during pregnancy (NVP) are commonly experienced by women in the first trimester of pregnancy. Although symptoms have existed for millennia, the current literature regarding dietary changes among these women, resultant birth outcomes of an affected pregnancy and the mechanism of hormones in the etiology of NVP are still under question. 
Published Feb. 24, 2011 8:39 PM - Last modified Dec. 13, 2012 2:53 PM