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Guest lecture: Luigi Fontana

Professor Luigi Fontana will present his data on: "Metabolic and molecular effects of calorie restriction in humans."

Speaker: Professor Luigi Fontana (MD, PhD) Department of Medicine, Salerno University Medical School, Italy & Division of Geriatrics and Nutritional Science, Washington University in St.Louis, USA.


Life expectancy in the world has increased dramatically during the last century; the number of older adults is expected to rise while the number of youth will decline in the next future. This demographic shift has considerable public health and economic implications since aging is associated with the development of serious chronic diseases.

Calorie restriction (CR) is the most effective nutritional intervention for slowing aging and preventing chronic disease in rodents. Similar effects are seen when the activity of nutrient-sensing pathways is reduced by mutations or chemical inhibitors. Calorie restriction also increases lifespan and protects against diabetes, cancer, and cardiovascular disease in rhesus monkeys, and in humans it causes metabolic and molecular changes that protect against these age-related diseases.

Welcome to a very good lecture on a very important topic!

Published Oct 3, 2012 12:23 PM