Hilde Loge Nilsen

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Phone +47-67963922
Mobile phone +47-93246618
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Visiting address Akershus University Hospital Sykehusveien 25 Epigen B2 1478 Lørenskog Norway
Postal address Akershus universitetssykehus 1478 LØRENSKOG

Academic Interests

The mechanisms responsible for sensing and repairing DNA damage that is either spontaneous (generated through the reaction of water and reactive oxygen species with DNA) or induced by chemotherapeutic agents and how DNA repair counteracts mutation, cancer, neurodegenerative diseases and aging.

Vacancies

We are currently recruiting a post doctoral fellow.

Positions held

  • 2013 - present:  Professor Department of Clinical Molecular Biology
  • 2009 - 2013:  Assistant Director, Biotechnology Centre of Oslo.
  • 2006 - present:  Problem-based learning supervisor, Medical Faculty, University of Oslo.
  • 2004 - 2013:  Group leader, “DNA Repair”, Biotechnology Centre of Oslo.

Background

Research

  • 2000 - 2004:  Post doctoral fellow, Cancer Research UK.
  • 2000:  Dr. ing. from the Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Tags: DNA repair, DNA damage, Cancer biology

Publications

  • Rolseth, Veslemøy; Gomez, Luisa Fernanda Luna; Olsen, Ann-Karin; Suganthan, Rajikala; Scheffler, Katja; Neurauter, Christine Gran; Esbensen, Qin Ying; Kusnierczyk, Anna; Hildrestrand, Gunn Annette; Graupner, Anne; Andersen, Jill Mari; Slupphaug, Geir; Klungland, Arne; Nilsen, Hilde & Bjørås, Magnar (2017). No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice . Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-04472-4 Full text in Research Archive
  • Fang, Evandro Fei; Kassahun, Henok; Croteau, Deborah L.; Scheibye-Knudsen, Morten; Marosi, Krisztina; Lu, Huiming; Shamanna, Raghavendra A.; Kalyanasundaram, Sumana; Bollineni, Ravi Chand; Wilson, Mark A.; Iser, Wendy B.; Wollman, Bradley N.; Morevati, Marya; Li, Jun; Kerr, Jesse S.; Lu, Qiping; Waltz, Tyler B.; Tian, Jane; Sinclair, David A.; Mattson, Mark P.; Nilsen, Hilde & Bohr, Vilhelm A. (2016). NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metabolism.  ISSN 1550-4131.  24(4), s 566- 581 . doi: 10.1016/j.cmet.2016.09.004
  • Scheibye-Knudsen, Morten; Tseng, Anne; Jensen, Martin Borch; Scheibye-Alsing, Karsten; Fang, Evandro Fei; Iyama, Teruaki; Bharti, Sanjay Kumar; Marosi, Krisztina; Froetscher, Lynn; Kassahun, Henok; Eckley, David Mark; Maul, Robert W; Bastian, Paul; De, Supriyo; Ghosh, Soumita; Nilsen, Hilde; Goldberg, Ilya G; Mattson, Mark P.; Wilson, David M.; Brosh, Robert M; Gorospe, Myriam & Bohr, Vilhelm A (2016). Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  113(44), s 12502- 12507 . doi: 10.1073/pnas.1610198113
  • Fang, Evandro E; Wollman, B; Kassahun, Henok; Nilsen, Hilde; Scheibye-Knudsen, Morten & Bohr, Vilhelm A (2015). Nuclear DNA repair Proteins in Mitochondrial Health and Aging.. Journal of Gerontology and Geriatric Medicine.  ISSN 2333-7214.  1, s 1- 2
  • Fang, Evandro Fei; Scheibye-Knudsen, Morten; Brace, Lear E; Kassahun, Henok; Sengupta, Tanima; Nilsen, Hilde; Mitchell, James R; Croteau, Deborah L & Bohr, Vilhelm A. (2014). Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction. Cell.  ISSN 0092-8674.  157(4) . doi: 10.1016/j.cell.2014.03.026
  • Jobert, Laure & Nilsen, Hilde (2014). Regulatory mechanisms of RNA function: Emerging roles of DNA repair enzymes. Cellular and Molecular Life Sciences (CMLS).  ISSN 1420-682X.  71(13), s 2451- 2465 . doi: 10.1007/s00018-014-1562-y
  • Jobert, Laure; Skjeldam, Hanne Kim; Dalhus, Bjørn; Galashevskaya, Anastasia; Vågbø, Cathrine Broberg; Bjørås, Magnar & Nilsen, Hilde (2013). The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control. Molecular Cell.  ISSN 1097-2765.  49(2), s 339- 345 . doi: 10.1016/j.molcel.2012.11.010
  • Sengupta, Tanima; Torgersen, Maria Lyngaas; Kassahun, Henok; Vellai, Tibor; Simonsen, Anne & Nilsen, Hilde (2013). The Base Excision Repair AP-endonucleases functions in the same pathways as Mismatch Repair for Activation of Checkpoint Mediated Autophagy. Nature Communications.  ISSN 2041-1723.  4, s 2674 . doi: 10.1038/ncomms3674
  • Forthun, Rakel Brendsdal; Sengupta, Tanima; Skjeldam, Hanne Kim; Lindvall, Jessica Margareta; Mccormack, Emmet Martin; Gjertsen, Bjørn Tore & Nilsen, Hilde (2012). Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid. PLoS ONE.  ISSN 1932-6203.  7(11) . doi: 10.1371/journal.pone.0048992
  • Tomazella, Gisele Guicardi; Kassahun, Henok; Nilsen, Hilde & Thiede, Bernd (2012). Quantitative Proteome Analysis Reveals RNA Processing Factors As Modulators of Ionizing Radiation-Induced Apoptosis in the C. elegans Germline. Journal of Proteome Research.  ISSN 1535-3893.  11(8), s 4277- 4288 . doi: 10.1021/pr300386z
  • Arczewska, Katarzyna; Baumeier, Christian; Kassahun, Henok; Sengupta, Tanima; Bjørås, Magnar; Kuśmierek, Jarosław T. & Nilsen, Hilde (2011). Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability. DNA Repair.  ISSN 1568-7864.  10(2), s 176- 187 . doi: 10.1016/j.dnarep.2010.10.009
  • Erdélyi, Péter; Borsos, Éva; Takács-Vellai, Krisztina; Kovács, Tibor; Kovács, Attila L.; Sigmond, Tímea; Hargitai, Balázs; Pasztor, Líz; Sengupta, Tanima; Dengg, Marlene; Pécsi, Ildikó; Tóth, Judit; Nilsen, Hilde; Vértessy, Beáta G. & Vellai, Tibor (2011). Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. Journal of Cell Science.  ISSN 0021-9533.  124(9), s 1510- 1518 . doi: 10.1242/jcs.080192
  • Arczewska, Katarzyna; Baumeier, Christian; Kassahun, Henok; Sengupta, Tanima; Bjørås, Magnar; Kuśmierek, Jarosław T. & Nilsen, Hilde (2010). Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability. DNA Repair.  ISSN 1568-7864. . doi: 10.1016/j.dnarep.2010.10.009
  • Fensgård, Øyvind; Kassahun, Henok; Izabela Agnieszka, Bombik; Rognes, Torbjørn; Lindvall, Jessica Margareta & Nilsen, Hilde (2010). A Two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways . Aging.  ISSN 1945-4589.
  • Skjeldam, Hanne Kim; Kassahun, Henok; Fensgård, Øyvind; Sengupta, Tanima; Babaie, Eshrat; Lindvall, Jessica Margareta; Arczewska, Katarzyna & Nilsen, Hilde (2010). Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents. DNA Repair.  ISSN 1568-7864.  9(8), s 861- 870 . doi: 10.1016/j.dnarep.2010.04.009
  • Zakaria, Chadi; Kassahun, Henok; Yang, Xiaoming; Labbé, Jean-Claude; Nilsen, Hilde & Ramotar, Dindial (2010). Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability. DNA Repair.  ISSN 1568-7864.  9(2), s 169- 176 . doi: 10.1016/j.dnarep.2009.11.007
  • Nilsen, Hilde; Corneliussen, Henriette; Fensgård, Øyvind; Grallert, Beata & Boye, Erik (2009). Global transcriptional response after exposure of fission yeast cells to ultraviolet light. BMC Cell Biology.  ISSN 1471-2121.  10, s 87
  • Nilsen, Hilde; Kassahun, Henok; Zakaria, Chadi; Yang, Xiaoming; Labbe, Jean-Claude & Ramotar, Dindial (2009). Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability. Accepted for publication in DNA repair,. DNA Repair.  ISSN 1568-7864. . doi: doi:10.1016/j.dnarep.2009.11.007
  • Nilsen, Hilde; Arczewska, Katarzyna; Michalickova, Katerina & Donaldson, Ian Matthew (2008). The contribution of DNA base damage to human cancer is modulated by the base excision repair interaction network. Critical reviews in oncogenesis.  ISSN 0893-9675.  14(4), s 217- 273
  • Schmidt, Frank; Strozynski, Margarita Anna; Salus, Sandra Suzanne; Nilsen, Hilde & Thiede, Bernd (2007). Rapid determination of amino acid incorporation by stable isotope labeling with amino acids in cell culture (SILAC). Rapid Communications in Mass Spectrometry.  ISSN 0951-4198.  21, s 3919- 3926 . doi: 10.1002/rcm.3290
  • Dengg, Marlene; Garcia-Muse, Tatiana; Gill, Stephen G.; Ashcroft, Neville; Boulton, Simon j. & Nilsen, Hilde (2006). Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. EMBO Reports.  ISSN 1469-221X.  7, s 1046- 1051 . doi: 10.1038/sj.embor.7400782
  • Andersen, Sonja Benedikte; Heine, T; Sneve, Ragnhild; Kønig, Imbritt; Krokan, Hans Einar; Epe, B & Nilsen, Hilde (2005). Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts. Carcinogenesis.  ISSN 0143-3334.  26(3), s 547- 555 . doi: 10.1093/carcin/bgh347
  • Nilsen, Hilde; An, Q & Lindahl, T (2005). Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice. Oncogene.  ISSN 0950-9232.  24(18), s 3063- 3066
  • Andersen, S; Ericsson, M; DAI, H; Peña-Diaz, J; Slupphaug, G; Nilsen, Hilde; Aarset, H & Krokan, HE (2005). Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice. DNA Repair.  ISSN 1568-7864.  4(12), s 1432- 1441
  • Andersen, S; Heine, T; Sneve, Ragnhild; Konig, I; Krokan, HE; Epe, B & Nilsen, Hilde (2005). Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts. Carcinogenesis.  ISSN 0143-3334.  26(3), s 547- 555
  • Nilsen, Hilde; An, Q & Lindahl, T (2004). Mutation frequenceies and AID activation state in B-cell lymphomas from Ung-deficient mice. Oncogene.  ISSN 0950-9232.
  • Nilsen, Hilde; Stamp, G; Andersen, Sonja; Hrivnak, G; Krokan, Hans Einar; Lindahl, T & Barnes, D.E (2003). Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas. Oncogene.  ISSN 0950-9232.  22, s 5381- 5386
  • Kavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Skorpen, Frank; Aas, Per Arne; Hagen, Lars; Krokan, Hans Einar & Slupphaug, Geir (2002). hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup. Journal of Biological Chemistry.  ISSN 0021-9258.  18, s 39926- 39936
  • Krokan, Hans Einar & Nilsen, Hilde (2001). Base excision repair in a network of defence and tolerance. Carcinogenesis.  ISSN 0143-3334.  22(Nr 7), s 987- 998
  • Krokan, Hans Einar; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank; Andersen, Sonja; Skjelbred, Camilla Furu; Akbari, Mansour; Aas, Per Arne & Slupphaug, Geir (2001). Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene. Progress in Nucleic Acid Research and Molecular Biology.  ISSN 0079-6603.  68, s 365- 386
  • Kvaløy, Kirsti; Nilsen, H.; Steinsbekk, Kristin; Nedal, Aina; Monterotti, Bruno; Akbari, Mansour & Krokan, Hans Einar (2001). Sequence variation in the human uracil-DNA glycosylase (UNG) gene. Mutation Research (DNA Repair).  ISSN 0921-8777.  461(4), s 325- 338 . doi: 10.1016/S0921-8777(00)00063-X,
  • Hals, Jardar; Bjerve, Kristian S; Nilsen, H.; Svalastog, A.G. & Ek, Johan (2000). Essential fatty acids in the nutrition of severely neurologically disabled children. British Journal of Nutrition.  ISSN 0007-1145.  83, s 219- 225
  • Krokan, Hans Einar; Nilsen, H.; Skorpen, Frank; Otterlei, Marit & Slupphaug, Geir (2000). Base excision repair in mammalian cells. FEBS Letters.  ISSN 0014-5793.  s 73- 77
  • Krokan, Hans Einar; Nilsen, Hilde; Skorpen, Frank; Otterlei, Marit & Slupphaug, Geir (2000). Base excision repair of DNA in mammalian cells. FEBS Letters.  ISSN 0014-5793.  s 73- 77
  • Nilsen, Hilde; Rosewell, I.; Robins, P.; Skjelbred, Camilla; Andersen, Sonja; Slupphaug, Geir; Krokan, Hans Einar; Lindahl, T. & Barnes, D.E. (2000). ) Ung-deficient mice reveal a primary role of the uracil-DNA glycosylase enzyme during DNA replication. Molecular Cell.  ISSN 1097-2765.  s 1059- 1065
  • Nilsen, Hilde; Rosewell, Ian; Robins, Peter; Skjelbred, Camilla; Andersen, Sonja; Slupphaug, Geir; Daly, Graham; Krokan, Hans Einar; Lindahl, Tomas & Barnes, Deborah E. (2000). URACIL-DNA Glycosylase (UNG)-Deficient Mice Reveal a Primary Role of the Enzyme during DNA Replication. Molecular Cell.  ISSN 1097-2765.  5, s 1059- 1065
  • Nilsen, Hilde; Steinsbekk, Kristin; Otterlei, Marit; Slupphaug, Geir; Aas, Per Arne & Krokan, Hans Einar (2000). Analysis of uracil-DNA glycosylases from the murine UNG gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Research.  ISSN 0305-1048.  s 2277- 2285
  • Nilsen, Hilde; Steinsbekk, Kristin; Otterlei, Marit; Slupphaug, Geir; Aas, Per Arne & Krokan, Hans Einar (2000). Analysis of uracil-DNA glycosylases from the murine Ung-gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Research.  ISSN 0305-1048.  s 2277- 2285
  • Krokan, Hans Einar; Skorpen, Frank; Otterlei, Marit; Bhariti, Sangeeta; Steinsbekk, Kristin; Nilsen, Hilde; Skjelbred, Camilla; Kavli, Bodil; Standal, Rune & Slupphaug, Geir (1999). Human uracil-DNA glycosylase. NATO Advances Study Institute series. Series A, Life sciences.  ISSN 0161-0449.  302
  • Nilsen, H.; Otterlei, Marit; Haug, T.; Solum, K.; Nagelhus, T.A; Skorpen, Frank & Krokan, Hans Einar (1997). Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Research.  ISSN 0305-1048.  s 750- 755
  • Nilsen, Hilde; Yazdankhah, Siamak Pour; Eftedal, Ingrid & Krokan, Hans Einar (1995). Sequence specificity for removal of uracil from U.A pairs and U.G mismatches by uracil-DNA glycosylase from Escherichia coli, and correlation with mutational hotspots. FEBS Letters.  ISSN 0014-5793.  362, s 205- 209

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  • Krokan, Hans Einar; Skorpen, Frank; Otterlei, Marit; Bharati, S; Steinsbekk, Kristin; Nilsen, Hilde; Nagelhus-Hernes, T; Haug, T; Aas, Per A; Akbari, M; Skjelbred, Camilla & Kavli, Bodil (1998). Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis. Plenum Press.  11 s.

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  • Nilsen, Hilde; Kroustallaki, Pinelopi; Alsøe, Lene; Huroz, Sergio C; Sarno, Antonio; Esbensen, Ying; Wang, Wei; Galashevskaya, Anastasia; Krokan, Hans Einar; Bjørås, Magnar & Gagos, Sarantis (2016). Telomere maintenance defects in mice deficient in SMUG1 uracil-DNA glycosylase.
  • Sarno, Antonio; Alsøe, Lene; Carracedo, Sergio; Tekin, Nuriya Basdag; Gupta, Tanima Sen; Jobert, Laure; Galashevskaya, Anastasia; Krokan, Hans Einar & Nilsen, Hilde (2016). UNG and SMUG1 complement each other in DNA uracil excision and DNA 5-hydroxymethyluracil originates from 5-hydroxymethylcytosine deamination in mice.
  • Wyller, Vegard Bruun; Jacobsen, Kristine; Dahl, Mai Britt; Nilsen, Hilde; Proske, Simone; Horter, Thorsten & Brun, Henrik (2016). Interferon gamma may improve cardiac function in Friedreich's ataxia cardiomyopathy. International Journal of Cardiology.  ISSN 0167-5273.  221, s 376- 378 . doi: 10.1016/j.ijcard.2016.06.288
  • Nilsen, Hilde (2013). Kan denne ormen avsløre at vitaminbruk er bortkastet. Aftenposten Innsikt.  ISSN 1890-6931.
  • Nilsen, Hilde & Nickelsen, Trine (2013). Vitaminpiller kan skade kroppens eget forsvar. Apollon : Forskningsmagasin for Universitetet i Oslo.  ISSN 0803-6926.
  • Nilsen, Hilde (2012). Liten orm gir mer effektiv kreftmedisin. Forskning.no : nettavis med nyheter fra norsk og internasjonal forskning.
  • Fensgård, Øyvind & Nilsen, Hilde (2010). DNA skader aldringsprosessen. NBS-nytt.  ISSN 0801-3535.  (5), s 9- 13
  • Fensgård, Øyvind & Nilsen, Hilde (2010). Global Genome Responses to DNA-Repair Deficiency Modulate Aging and Stress Response Pathways.
  • Nilsen, Hilde (2010). A two-tiered compensatory response to loss of DNA repair modulated aging and stress-response pathways.
  • Nilsen, Hilde (2010). A two-tiered compensatory response to loss of DNA repair modulated aging and stress-response pathways.
  • Nilsen, Hilde (2010). DNA repair dependent signalling of cell death responses to 5-Fluorouracil.
  • Nilsen, Hilde (2010, 16. mars). Liten orm avslører våre aldringsprosesser.  Apollon.
  • Nilsen, Hilde (2010, 08. mars). Liten orm hjelper oss til bedre liv.  Aftenposten.
  • Nilsen, Hilde (2010, 25. mars). Om forsknings arbeider i Bioteknologisenteret. [TV].  NRK Østlandssendningen.
  • Fensgård, Øyvind; Lindvall, Jessica Margareta; Kassahun, Henok; Rognes, Torbjørn & Nilsen, Hilde (2009). Microarray analysis of BER mutants.
  • Fensgård, Øyvind; Lindvall, Jessica; Kassahun, Henok; Rognes, Torbjørn & Nilsen, Hilde (2009). Microarray analysis of BER mutants.
  • Nilsen, Hilde (2009). DNA repair modulates responses to chemotherapeutic agents.
  • Nilsen, Hilde (2009). Two-tiered response to loss of DNA damage in C. elegans.
  • Nilsen, Hilde (2009). Uracil DNA glycosylase is required for apoptosis in response to 5-fluorouracil in C. elegans.
  • Nilsen, Hilde & Dengg, Marlene (2006). Caenorhabditis elegans and the DNA damage response. NBS-nytt.  ISSN 0801-3535.  30(3), s 22- 25
  • Nilsen, Hilde (2005). Cellular responses to endogenous DNA damage.
  • Nilsen, Hilde (2005). Genetic studies of repair of endogenous DNA damage.
  • Nilsen, Hilde (2005). Using C.elegans to study the DNA damage response.
  • Nilsen, Hilde (2005). Using C.elegans to study the DNA damage response”.
  • Nilsen, Hilde (2005). Using Caenorhabditis elegans to study cellular responses to endogenous DNA damage.
  • Nilsen, Hilde (2004). The UNG uracil -NDA glycosylase- a region specific guardian of the genome.
  • Nilsen, Hilde (2004). The UNG uracil-DNA glycosylase- a region specific guardian of the genome.
  • Andersen, Sonja; Nilsen, Hilde; Grøsvik, K; Kønig, I; Sneve, R; Slupphaug, Geir & Krokan, Hans Einar (2002). Uracil-DNA glycosylase knockout mice.
  • Andersen, Sonja; Nilsen, Hilde; Grøsvik, K; Kønig, I; Sneve, R; Slupphaug, Geir; Stamp, G; Hrivnak, G; Lindahl, T; Barnes, D.E & Krokan, Hans Einar (2002). "URACIL-DNAGLYCOSYLASE KNOCKOUT MICE-effects on lifespan and health. Characterisation of uracil removing activities in wild type and Ung deficient mice.".
  • Kavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Aas, Per Arne; Krokan, Hans Einar & Slupphaug, Geir (2002). Substrate preference and enzyme kinetics reveal distinct properties of UNG2 and SMUG1 in cellular base-excision repair; hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches and U in single stranded DNA, with hSMUG1 as a broad specificity backup.
  • Nilsen, H.; Robins, P; Haushalters, K.; Krokan, Hans Einar; Verdine, G.; Barnes, D. & Lindahl, T. (2001). Base excision repair of uracil in mammalian cells.
  • Slupphaug, Geir; Skorpen, Frank; Nilsen, H.; Fenstad, M.; Rosello, Ch.; Otterlei, Marit; Aas, P.A. & Krokan, Hans Einar (2001). Functional implications of the UNG2 regulatory domain in BER and transcription regulation.
  • Krokan, Hans Einar; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank; Andersen, Sonja; Slupphaug, Geir; Barnes, Deborah & Lindahl, Tomas (2000). Structure-function aspects of human uracil-DNA glycosylase and its interactions with other proteins.
  • Nilsen, Hilde (2000). Uracil-DNA glycosylase in protection of genomic integrity: from Escherichia coli to mammals.
  • Nilsen, Hilde (2000). Uracil-DNA glycosylase in protection of genomic integrity: from Escherichia coli to mammals.
  • Nilsen, Hilde; Roswell, Ian; Robins, Peter; Slupphaug, Geir; Steinsbekk, Kristin; Otterlei, Marit; Andersen, Sonja; Lindahl, Tomas; Barnes, Deborah & Krokan, Hans Einar (2000). Characterisation Of The Major Murine Uracil-DNA Glycosylase And Expression Patterns And Generation of ung/-Knockout Mice.
  • Barnes, D.E.; Klungland, A.; Nilsen, Hilde; Morita, M.; Epe, B.; Krokan, Hans Einar; Seeberg, E. & Lindahl, T. (1999). Excision Repair of DNA Damage 11.
  • Krokan, Hans Einar; Slupphaug, Geir; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil & Skorpen, Frank (1999). Excicion Repar of DNA Damage 1.
  • Nilsen, Hilde; Barnes, D.E.; Lindahl, T. & Krokan, Hans Einar (1999). Mouse model deficient in uracil-DNA glycosylase encoded by the Ung gene: effects on spontaneous mutation frequency.
  • Nilsen, Anne Birgitta & Nilsen, Hilde (1998). Når ja betyr nei. Tidsskriftet sykepleien.  ISSN 0806-7511.  (13)
  • Nilsen, Hilde (1998). Polymorfismer i UDG/knock out mus.
  • Nilsen, Anne Birgitta & Nilsen, Hilde (1998). Å forstå hverandre krever kunnskap. Jordmorbladet.  ISSN 0805-0562.

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Published Sep. 4, 2013 12:57 PM - Last modified Apr. 28, 2017 8:17 AM

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