Tom Eirik Mollnes

Professor II - Department of Immunology
Image of Tom Eirik Mollnes
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Phone +47-22207287
Mobile phone +47-90630015
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Ekdahl KN, Mollnes TE, Nilsson PH. (2017) Properdin binding to complement activating surfaces depends on initial C3b-deposition. Proc Natl Acad Sci USA. doi: 10.1073/pnas.1612385114
  • Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE. (2017) Dual inhibition of complement and toll-like receptors as a novel approach to treat inflammatory diseases – C3 or C5 emerge together with CD14 as promising targets. J Leukocyte Biol 101:193-204.
  • Nymo S, Gustavsen A, Nilsson PH, Lau C, Espevik T, Mollnes TE. (2016) Human endothelial cell activation by Escherichia coli and Staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. J Immunol 196:2293-2299.
  • Meroni PL, Macor P, Durigutto P, De Maso L, Gerosa M, Ferraresso M, Borghi M, Mollnes TE, Tedesco F. (2016) Complement activation in anti-phospholipid syndrome and its inhibition to prevent re-thrombosis after arterial surgery. Blood 127:365-367.
  • Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing TLR4-MD2. J Infect Dis 214:140-150.
  • Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Crit Care 19:415:1-8.
  • Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE.(2014) Double-blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. J Immunol 192:5324-5331.
  • Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE. (2011) Alginate microbeads are complement-compatible in contrast to polycation containing microcapsules revealed by a human whole blood model. Acta Biomater 7:25678.
  • Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE. (2011) Ornithodoros moubata complement inhibitor (OmCI) is an equally effective C5 inhibitor in pig and human. J Immunol 187:4913-4919.
  • Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE. (2010) CD14-inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli-sepsis in pigs. FASEB J 24:712-722.
  • Husebye H, Hjelmseth M, Stenvik J, Samstad E, Skjeldal F, Halaas Ø, Nilsen, NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T. (2010) The Rab11a GTPase selectively controls Toll-like receptor 4 induced IRF3 activation by regulating trafficking to phagosomes. Immunity 33:583-596.
  • Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE. (2009) Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature. Proc Natl Acad Sci USA 106:15861-15866.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE. (2004) Excersice reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J 25:350-356.
  • Sprong T, Brandtzaeg P, Fung M, Pharo A, Høiby AE, Michaelsen T, Aase A, van der Meer JWM, van Deuren M, Mollnes TE. (2003) Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis. Blood 102:3702-3710.
  • Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR, Fung M, Mollnes TE. (2003) Mechanism of complement activation and its role in the inflammatory response following thoraco-abdominal aortic aneurysm repair. Circulation 108:849-856.
  • Mollnes TE, Brekke OL, Fung M, Fure H, Christiansen D, Bergseth G, Videm V, Lappegård KT, Köhl J, Lambris J. (2002) Essential role of the C5a receptor in E. coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100:1869-1877.
  • Aukrust P, Gullestad L, Lappegård KT, Ueland T, Aass H, Wikeby L, Simonsen S, Frøland SS, Mollnes TE. (2001) Complement activation in patients with congestive heart failure - effect of high-dose intravenous immunoglobulin treatment. Circulation 104:1494-1500.
  • Brandtzaeg P, Høgåsen K, Kierulf P, Mollnes TE. (1996) The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation. J Infect Dis 173:647-655.
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik & Espevik, Terje (2017). Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.. Journal of Immunology.  ISSN 0022-1767. . doi: 10.4049/jimmunol.1700302
  • Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje & Mollnes, Tom Eirik (2017). Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.. Journal of Leukocyte Biology.  ISSN 0741-5400.  101(1), s 193- 204 . doi: 10.1189/jlb.3VMR0316-132R Full text in Research Archive
  • Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Bjerve, Kristian S; Michelsen, Annika; Aukrust, Pål; Schmidt, EB; Christensen, JH & Jenssen, Trond Geir (2017). Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition (Print).  ISSN 1051-2276.  27(3), s 161- 168 . doi: 10.1053/j.jrn.2016.09.008
  • Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B. & Garred, Peter (2017). Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-04121-w
  • Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Brekke, Ole-Lars & Rokstad, Anne Mari (2017). Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII . Acta Biomaterialia.  ISSN 1742-7061.  58, s 158- 167 . doi: 10.1016/j.actbio.2017.05.052 Full text in Research Archive
  • Gustavsen, Alice; Skattum, Lillemor; Bergseth, Grete; Lorentzen, Bjørg; Fløisand, Yngvar; Bosnes, Vidar; Mollnes, Tom Eirik & Barratt-Due, Andreas (2017). Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome. Medicine (Baltimore, Md.).  ISSN 0025-7974.  96(11) . doi: 10.1097/MD.0000000000006338
  • Harboe, Morten; Johnson, Christina; Nymo, Stig Haugset; Ekholt, Karin; Schjalm, Camilla; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik & Nilsson, Per (2017). Properdin binding to complement activating surfaces depends on initial C3b deposition. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  114(4), s E534- E539 . doi: 10.1073/pnas.1612385114
  • Hennø, Linda Torrissen; Storjord, Elin; Christiansen, Dorte; Bergseth, Grete; Ludviksen, Judith K; Fure, Hilde; Barene, Svein; Nielsen, Erik Waage; Mollnes, Tom Eirik & Brekke, Ole Lars (2017). Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines ? Consequences for defining reference values in healthy humans . Cytokine.  ISSN 1043-4666.  97, s 86- 95 . doi: 10.1016/j.cyto.2017.05.014
  • Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik & Espevik, Terje (2017). Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology.  ISSN 0161-5890.  84, s 43- 50 . doi: 10.1016/j.molimm.2016.09.019
  • Pischke, Søren Erik; Gustavsen, Alice; Orrem, HL; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas & Mollnes, Tom Eirik (2017). Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function. Basic Research in Cardiology.  ISSN 0300-8428.  112:20(3), s 1- 14 . doi: 10.1007/s00395-017-0610-9
  • Shahini, Negar; Michelsen, Annika; Nilsson, Per; Ekholt, Karin; Gullestad, Lars; Broch, Kaspar; Dahl, Christen Peder; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Yndestad, Arne & Louwe, Maria Cornelia (2017). The alternative complement pathway is dysregulated in patients with chronic heart failure. Scientific Reports.  ISSN 2045-2322.  7 . doi: 10.1038/srep42532
  • Shields, Kelly J.; Mollnes, Tom Eirik; Eidet, Jon Roger; Mikkelsen, Knut; Almdahl, Sven Martin; Bottazzi, Barbara; Lyberg, Torstein; Manzi, Susan; Ahearn, Joseph M & Hollan, Ivana (2017). Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases. PLoS ONE.  ISSN 1932-6203.  12(3) . doi: 10.1371/journal.pone.0174577
  • Smedbråten, Julia; Sagedal, Solbjørg; Åsberg, Anders; Hartmann, Anders; Rollag, Halvor; Mjøen, Geir; Fagerland, Morten; Hansen, S. W. K.; Mollnes, Tom Eirik & Thiel, S. (2017). Collectin liver 1 and collectin kidney 1 of the lectin complement pathway are associated with mortality after kidney transplantation. American Journal of Transplantation.  ISSN 1600-6135.  17(1), s 265- 271 . doi: 10.1111/ajt.13933
  • Storjord, Elin; Dahl, Jim André; Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Goldbeck-Wood, Sandy; Karlsen, Bård Ove; Berg, Kristin Sandal; Mollnes, Tom Eirik; Nielsen, Erik Waage & Brekke, Ole Lars (2017). Systemic inflammation in acute intermittent porphyria:a case–control study. Clinical and Experimental Immunology.  ISSN 0009-9104.  187(3), s 466- 479 . doi: 10.1111/cei.12899
  • Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per; Sarode, Apoorva; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik & Moghimi, Seyed Moein (2017). Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes. Nature Nanotechnology.  ISSN 1748-3387.  12(6), s 589- 594 . doi: 10.1038/nnano.2017.47
  • Wolf-Grosse, Susann; Rokstad, Anne Mari; Ali, Syed; Lambris, JD; Mollnes, Tom Eirik; Nilsen, Asbjørn Magne & Stenvik, Jørgen (2017). Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model. International Journal of Nanomedicine.  ISSN 1176-9114.  12, s 3927- 3940 . doi: 10.2147/IJN.S136453 Full text in Research Archive
  • Aresvik, Dina; Lima, Kari; Øverland, Torstein; Mollnes, Tom Eirik & Abrahamsen, Tore G (2016). Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome. Scandinavian Journal of Immunology.  ISSN 0300-9475.  83(3), s 188- 194 . doi: 10.1111/sji.12406
  • Barratt-Due, Andreas; Fløisand, Yngvar; Lang, Hilde Elisabeth; Kvam, Ann Kristin; Holme, Pål Andre; Bergseth, Grete; Tjønnfjord, Geir Erland & Mollnes, Tom Eirik (2016). Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome.. Rheumatology.  ISSN 1462-0324. . doi: 10.1093/rheumatology/kew040 Full text in Research Archive
  • Garabet, Lamya Samir Noori; Gilboe, Inge-Margrethe; Mowinckel, Marie-Christine; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Sandset, Per Morten & Jacobsen, Eva-Marie (2016). Antiphospholipid antibodies are associated with low levels of complement C3 and C4 in patients with systemic Lupus Erythematosus. Scandinavian Journal of Immunology.  ISSN 0300-9475.  84(2), s 95- 99 . doi: 10.1111/sji.12445
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje & Mollnes, Tom Eirik (2016). Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases.  ISSN 0022-1899.  214(1), s 140- 150 . doi: 10.1093/infdis/jiw100 Full text in Research Archive
  • Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik & Ueland, Thor (2016). Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis . Neuropsychiatric Disease and Treatment.  ISSN 1176-6328.  12, s 817- 822 . doi: 10.2147/NDT.S101925 Full text in Research Archive
  • Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin; Nicholls, Ian A; Mollnes, Tom Eirik; Fromell, Karin; Nilsson, Bo & Ekdahl, Kristina Nilsson (2016). Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood . Biomaterials.  ISSN 0142-9612.  77, s 111- 119 . doi: 10.1016/j.biomaterials.2015.10.067
  • Jørgensen, Silje Fjellgård; Trøseid, Marius; Kummen, Martin; Anmarkrud, Jarl Andreas; Michelsen, Annika; Osnes, Liv T. N.; Holm, Kristian; Høivik, Marte; Rashidi, Azita; Dahl, Christen Peder; Vesterhus, Mette; Halvorsen, Bente; Mollnes, Tom Eirik; Berge, Rolf Kristian; Moum, Bjørn; Lundin, Knut Erik Aslaksen; Fevang, Børre; Ueland, Thor; Karlsen, Tom Hemming; Aukrust, Pål & Hov, Johannes Espolin Roksund (2016). Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology.  ISSN 1935-3456. . doi: 10.1038/mi.2016.18
  • Landsem, Anne; Fure, Hilde; Mollnes, Tom Eirik; Nielsen, Erik Waage & Brekke, Ole Lars (2016). C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry. Thrombosis Research.  ISSN 0049-3848.  143, s 63- 70 . doi: 10.1016/j.thromres.2016.04.024
  • Lappegård, Knut Tore; Enebakk, Terje; Thunhaug, Hilde; Ludviksen, Judith K; Mollnes, Tom Eirik & Hovland, Anders (2016). LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response. Journal of Clinical Lipidology.  ISSN 1933-2874.  10(6), s 1481- 1487 . doi: 10.1016/j.jacl.2016.09.001
  • Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje & Mollnes, Tom Eirik (2016). Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology.  ISSN 0022-1767.  196(5), s 2293- 2299 . doi: 10.4049/jimmunol.1502220 Full text in Research Archive
  • Otterdal, Kari; Portillo, Aránzazu; Astrup, Elisabeth; Ludviksen, Judith K; Davi, Giovanni; Holm, Sverre; Santilli, Francesca; Vitale, Giustina; Raoult, Didier; Olano, Juan P.; Schjalm, Camilla; Halvorsen, Bente; Oteo, José A.; Mollnes, Tom Eirik; Aukrust, Pål & Nilsson, Per (2016). High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation. Cytokine.  ISSN 1043-4666.  83, s 269- 274 . doi: 10.1016/j.cyto.2016.05.006
  • Otterdal, Kari; Portillo, Aránzazu; Astrup, Elisabeth; Ludviksen, Judith K; Schjalm, Camilla; Raoult, Didier; Olano, Juan Pablo; Halvorsen, Bente; Oteo Revuelta, José Antonio; Aukrust, Pål; Mollnes, Tom Eirik & Nilsson, Per (2016). Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo. Clinical Microbiology and Infection.  ISSN 1198-743X.  22(8), s 734.e1- 734.e6 . doi: 10.1016/j.cmi.2016.05.010
  • Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente; Holm, Sverre; Aukrust, Pål; Bakke, Siril Skaret; Sporsheim, Bjørnar; Nervik, Ingunn; Niyonzima, Nathalie; Bartels, Emil D.; Stahl, Gregory L.; Mollnes, Tom Eirik; Espevik, Terje & Garred, Peter (2016). Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology.  ISSN 0022-1767.  196(12), s 5064- 5074 . doi: 10.4049/jimmunol.1502595
  • Seip, Knut Fredrik; Evjenth, Bjørg; Hovland, Anders; Dybwik, Knut Gustav; Johansen, Harald Thidemann; Fure, Hilde; Mollnes, Tom Eirik & Nielsen, Erik Waage (2016). Bradykinin-Induced Shock Increase Exhaled Nitric Oxide, Complement Activation and Cytokine Production in Pigs . Journal of Cardiology & Clinical Research.  ISSN 2333-6676.  4(2) Full text in Research Archive
  • SMEDBRÅTEN, Julia; Mjøen, Geir; Hartmann, Anders; Åsberg, Anders; Rollag, Halvor; Mollnes, Tom Eirik; Sandvik, Leiv; Fagerland, Morten; Thiel, Steffen & Sagedal, Solbjørg (2016). Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients. BMC Nephrology.  ISSN 1471-2369.  17(1) . doi: 10.1186/s12882-016-0373-9 Full text in Research Archive
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne; Trøseid, Marius; Tasken, Kjetil & Dyrhol-Riise, Anne Ma (2016). Plasma IP-10 is increased in immunological nonresponders and associated with activated regulatory T cells and persisting low CD4 counts. Journal of Acquired Immune Deficiency Syndromes.  ISSN 1525-4135.  73(2), s 138- 148 . doi: 10.1097/QAI.0000000000001080
  • Stylianou, Eva; Ueland, Thor; Borchsenius, Fredrik; Michelsen, Annika; Øvstebø, Reidun; Mollnes, Tom Eirik; Skjønsberg, Ole Henning & Aukrust, Pål (2016). Specific allergen immunotherapy: Effect on IgE, IgG4 and chemokines in patients with allergic rhinitis. Scandinavian Journal of Clinical and Laboratory Investigation.  ISSN 0036-5513.  76(2), s 118- 127 . doi: 10.3109/00365513.2015.1110856
  • Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje & Rokstad, Anne Mari (2016). Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation . Journal of Controlled Release.  ISSN 0168-3659.  229, s 58- 69 . doi: 10.1016/j.jconrel.2016.03.021 Full text in Research Archive
  • Asprusten, Tarjei Tørre; Fagermoen, Frode Even; Sulheim, Dag; Skovlund, Eva; Sørensen, Øystein; Mollnes, Tom Eirik & Wyller, Vegard Bruun (2015). Study findings challenge the content validity of the Canadian Consensus Criteria for adolescent chronic fatigue syndrome. Acta Paediatrica.  ISSN 0803-5253.  104(5), s 498- 503 . doi: 10.1111/apa.12950
  • Berg, Åse; Otterdal, Kari; Patel, Sam; Gonca, Miguel; David, Catarina; Dalen, Ingvild; Nymo, Stig Haugset; Nilsson, Margareta; Nordling, Sofia; Magnusson, Peetra U.; Ueland, Thor; Prato, Mauro; Giribaldi, Giuliana; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina & Nilsson, Per (2015). Complement activation correlates with disease severity and contributes to cytokine responses in plasmodium falciparum malaria. Journal of Infectious Diseases.  ISSN 0022-1899.  212(10), s 1835- 1840 . doi: 10.1093/infdis/jiv283
  • Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje & Stenvik, Jørgen (2015). TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology.  ISSN 0022-1767.  195(3), s 1100- 1111 . doi: 10.4049/jimmunol.1403176 Full text in Research Archive
  • Blom, Anna M.; Österborg, Anders; Mollnes, Tom Eirik & Okroj, Marcin (2015). Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation. Molecular Immunology.  ISSN 0161-5890.  66(2), s 164- 170 . doi: 10.1016/j.molimm.2015.02.029
  • Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna; Espevik, Terje; Thorgersen, Ebbe Billmann & Mollnes, Tom Eirik (2015). The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology.  ISSN 0009-9104.  181(3), s 457- 467 . doi: 10.1111/cei.12645
  • Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, Anjan K.; Rieben, Robert; Nunn, Miles A.; Barratt-Due, Andreas & Mollnes, Tom Eirik (2015). Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14. Immunobiology.  ISSN 0171-2985.  220(8), s 999- 1005 . doi: 10.1016/j.imbio.2015.04.002
  • Engberg, Anna E.; Nilsson, Per; Huang, Shan; Fromell, Karin; Hamad, Osama A.; Mollnes, Tom Eirik; Rosengren-Holmberg, Jenny P; Sandholm, Kerstin; Teramura, Yuji; Nicholls, Ian A; Nilsson, Bo & Ekdahl, Kristina N. (2015). Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma. Biomaterials.  ISSN 0142-9612.  36, s 55- 65 . doi: 10.1016/j.biomaterials.2014.09.011
  • Fretland, Åsmund Avdem; Sokolov, Andrey; Postriganova, Nadezda; Kazaryan, Airazat M.; Pischke, Søren Erik; Nilsson, Per; Rognes, Ingrid Nygren; Bjørnbeth, Bjørn Atle; Fagerland, Morten; Mollnes, Tom Eirik & Edwin, Bjørn (2015). Inflammatory response after laparoscopic versus open resection of colorectal liver metastases: Data from the oslo-comet trial. Medicine (Baltimore, Md.).  ISSN 0025-7974.  94:e1786(42) . doi: 10.1097/MD.0000000000001786 Full text in Research Archive
  • Hallstensen, Randi; Bergseth, Grete; Foss, Stian; Jæger, Steinar; Gedde-Dahl, Thobias; Holt, jan; Christiansen, Dorte; Lau, Corinna; Brekke, Ole Lars; Armstrong, Elina; Stefanovic, Vedran; Andersen, Jan Terje; Sandlie, Inger & Mollnes, Tom Eirik (2015). Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. Immunobiology.  ISSN 0171-2985.  220(4), s 452- 459 . doi: 10.1016/j.imbio.2014.11.003 Full text in Research Archive
  • Hein, E; Munthe-Fog, Lea; Thiara, Amrit Paul Singh; Fiane, Arnt E; Mollnes, Tom Eirik & Garred, P (2015). Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo. Clinical and Experimental Immunology.  ISSN 0009-9104.  179(2), s 294- 299 . doi: 10.1111/cei.12446
  • Hellerud, Bernt C; Olstad, Ole Kristoffer; Nielsen, Erik W.; Siebke, Anne-Marie; Skadberg, Øyvind; Thorgersen, Ebbe Billmann; Vege, Åshild; Mollnes, Tom Eirik & Brandtzæg, Petter (2015). Massive organ inflammation in experimental and in clinical meningococcal septic shock. Shock.  ISSN 1073-2322.  44(5), s 458- 469 . doi: 10.1097/SHK.0000000000000441
  • Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore; Espevik, Terje & Mollnes, Tom Eirik (2015). The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis.  ISSN 0021-9150.  241(2), s 480- 494 . doi: 10.1016/j.atherosclerosis.2015.05.038 Full text in Research Archive
  • Khan, Faraz Hameed; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Mollnes, Tom Eirik; Tønnessen, Tor Inge & Pischke, Søren Erik (2015). Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis. Scandinavian Journal of Immunology.  ISSN 0300-9475.  82(5), s 467- 475 . doi: 10.1111/sji.12332
  • Landsem, Anne; Fure, Hilde; Christiansen, Dorte; Nielsen, Erik Waage; Østerud, Bjarne; Mollnes, Tom Eirik & Brekke, Ole Lars (2015). The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood. Clinical and Experimental Immunology.  ISSN 0009-9104.  182(1), s 81- 89 . doi: 10.1111/cei.12663
  • Lappegård, Knut Tore; Bjerre, Anna Kristina; Tjønnfjord, Geir Erland & Mollnes, Tom Eirik (2015). Terapeutisk komplementhemming – fra eksperimentell til klinisk medisin . Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  135(19), s 1745- 1749 . doi: 10.4045/tidsskr.15.0049
  • Lappegård, Knut Tore; Bjørnstad, Hanne; Mollnes, Tom Eirik & Hovland, Anders (2015). Effect of Cardiac Resynchronization Therapy on Inflammation in Congestive Heart Failure: A Review. Scandinavian Journal of Immunology.  ISSN 0300-9475.  82(3), s 191- 198 . doi: 10.1111/sji.12328
  • Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind & Mollnes, Tom Eirik (2015). CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLoS ONE.  ISSN 1932-6203.  10(2) . doi: 10.1371/journal.pone.0117261 Full text in Research Archive
  • Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind & Mollnes, Tom Eirik (2015). Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data.  ISSN 2213-5960.  5, s 176- 183 . doi: 10.1016/j.gdata.2015.05.019 Full text in Research Archive
  • Lindenskov, Paal Helge H.; Castellheim, Albert; Saugstad, Ola Didrik & Mollnes, Tom Eirik (2015). Meconium aspiration syndrome: Possible pathophysiological mechanisms and future potential therapies. Neonatology.  ISSN 1661-7800.  107(3), s 225- 230 . doi: 10.1159/000369373
  • Neupane, Sudan Prasad; Lien, Lars; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål & Bramness, Jørgen Gustav (2015). Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders . Alcohol.  ISSN 0741-8329.  49(5), s 471- 478 . doi: 10.1016/j.alcohol.2015.01.012
  • Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari; Wright, Samuel; Damås, Jan Kristian; Mollnes, Tom Eirik; Latz, Eicke & Espevik, Terje (2015). Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology.  ISSN 0022-1767.  195(1), s 257- 264 . doi: 10.4049/jimmunol.1403044
  • Owen, E. Patricia; Würzner, Reinhard; Leisegang, Felicity; Rizkallah, Pierre; Whitelaw, Andrew; Simpson, John; Thomas, Andrew D.; Harris, Claire L.; Giles, Joanna L.; Hellerud, Bernt C; Mollnes, Tom Eirik; Morgan, B. Paul; Potter, Paul C. & Orren, Ann (2015). A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Molecular Immunology.  ISSN 0161-5890.  64(1), s 170- 176 . doi: 10.1016/j.molimm.2014.11.010
  • Prebensen, Christian; Ueland, Thor; Michelsen, Annika; Lind, Andreas; Pettersen, Frank Olav; Mollnes, Tom Eirik; Aukrust, Pål; Dyrhol-Riise, Anne Ma & Kvale, Dag (2015). High MIP-1β levels in plasma predict long-term immunological nonresponse to suppressive antiretroviral therapy in HIV infection. Journal of Acquired Immune Deficiency Syndromes.  ISSN 1525-4135.  69(4), s 395- 402 . doi: 10.1097/QAI.0000000000000617
  • Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.; Fure, Hilde; Lau, Corinna; Brekke, Ole Lars; Huber-Lang, Markus; Espevik, Terje; Barratt-Due, Andreas; Nielsen, Erik Waage & Mollnes, Tom Eirik (2015). Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care.  ISSN 1466-609X.  19:415 . doi: 10.1186/s13054-015-1129-9 Full text in Research Archive
  • Smedbråten, Yuliya V.; Sagedal, Solbjørg; Mjøen, Geir; Hartmann, Anders; Fagerland, Morten; Rollag, Halvor; Mollnes, Tom Eirik & Thiel, Steffen (2015). High Ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients. Transplantation.  ISSN 0041-1337.  99(4), s 791- 796 . doi: 10.1097/TP.0000000000000422
  • Volokhina, E.B.; Westra, Dineke; van der Velden, Thea J.A.M.; van de Kar, Nicole C.A.J.; Mollnes, Tom Eirik & van den Heuvel, Lambert P. (2015). Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission. Clinical and Experimental Immunology.  ISSN 0009-9104.  181(2), s 306- 313 . doi: 10.1111/cei.12426
  • Volokhina, Elena B.; van de Kar, Nicole C.A.J.; Bergseth, Grethe; van der Velden, Thea J.A.M.; Westra, Dineke; Wetzels, Jack F.M.; van den Heuvel, Lambertus P. & Mollnes, Tom Eirik (2015). Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome. Clinical Immunology.  ISSN 1521-6616.  160(2), s 237- 243 . doi: 10.1016/j.clim.2015.05.018 Full text in Research Archive
  • Wergeland, Ida; Pullar, Nadine Durema; Assmus, Jörg; Ueland, Thor; Tonby, Kristian; Feruglio, Siri; Kvale, Dag; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik & Dyrhol-Riise, Anne Ma (2015). IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy. Journal of Infection.  ISSN 0163-4453.  70(4), s 381- 391 . doi: 10.1016/j.jinf.2014.12.019 Full text in Research Archive
  • Würzner, Reinhard; Tedesco, Francesco; Garred, Peter; Mollnes, Tom Eirik; Truedsson, Lennart; Turner, Malcolm W.; Sommarin, Yngve; Wieslander, Jörgen & Sim, Robert B. (2015). European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha. Molecular Immunology.  ISSN 0161-5890.  68(1), s 63- 66 . doi: 10.1016/j.molimm.2015.05.003
  • Wyller, Vegard Bruun; Sørensen, Øystein; Sulheim, Dag; Fagermoen, Frode Even; Ueland, Thor & Mollnes, Tom Eirik (2015). Plasma cytokine expression in adolescent chronic fatigue syndrome. Brain, behavior, and immunity.  ISSN 0889-1591.  46, s 80- 86 . doi: 10.1016/j.bbi.2014.12.025
  • Berg, Åse; Patel, Sam; Gonca, Miguel; Catarina, David; Otterdal, Kari; Ueland, Thor; Dalen, Ingvild; Kvaløy, Jan Terje; Mollnes, Tom Eirik; Aukrust, Pål & Langeland, Nina (2014). Cytokine network in adults with falciparum malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity. PLoS ONE.  ISSN 1932-6203.  9(12) . doi: 10.1371/journal.pone.0114480 Full text in Research Archive
  • Bisschops, Laurens L.A.; van der Hoeven, Johannes G.; Mollnes, Tom Eirik & Hoedemaekers, Cornelia W.E. (2014). Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study . Critical Care.  ISSN 1466-609X.  18(546) . doi: 10.1186/s13054-014-0546-5
  • Blom, AM; Volokhina, E.B.; Fransson, V; Strömberg, P; Berghard, L; Viktorelius, M; Mollnes, Tom Eirik; Lopez-Trascasa, M; van den Heuvel, Lambert P.; Goodship, T.H.; Marchbank, K & Okroj, M (2014). A novel method for direct measurement of complement convertases activity in human serum. Clinical and Experimental Immunology.  ISSN 0009-9104.  178(1), s 142- 153 . doi: 10.1111/cei.12388
  • Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lambris, John D.; Barratt-Due, Andreas & Mollnes, Tom Eirik (2014). Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood. Innate Immunity.  ISSN 1753-4259.  20(1), s 68- 77 . doi: 10.1177/1753425913482993
  • Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.; Denk, Stephanie; Gaus, Wilhelm; Espevik, Terje & Mollnes, Tom Eirik (2014). Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology.  ISSN 0022-1767.  192(11), s 5324- 5331 . doi: 10.4049/jimmunol.1400341
  • Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik & Hovland, Anders (2014). A vital role for complement in heart disease. Molecular Immunology.  ISSN 0161-5890.  61(2), s 126- 134 . doi: 10.1016/j.molimm.2014.06.036
  • Lind, Andreas; Brekke, Kristin; Pettersen, Frank Olav; Mollnes, Tom Eirik; Trøseid, Marius & Kvale, Dag (2014). A parameter for IL-10 and TGF-β mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers. PLoS ONE.  ISSN 1932-6203.  9(1) . doi: 10.1371/journal.pone.0085604 Full text in Research Archive
  • Neupane, Sudan Prasad; Lien, Lars; Martinez, Priscilla; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut & Bramness, Jørgen Gustav (2014). High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders. CNS Neuroscience & Therapeutics.  ISSN 1755-5930.  20(10), s 898- 904 . doi: 10.1111/cns.12303
  • Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje & Mollnes, Tom Eirik (2014). Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology.  ISSN 0171-2985.  219(10), s 786- 792 . doi: 10.1016/j.imbio.2014.06.006 Full text in Research Archive
  • Salvesen, Bodil; Curstedt, Tore; Mollnes, Tom Eirik & Saugstad, Ola Didrik (2014). Effects of natural versus synthetic surfactant with SP-B and SP-C analogs in a porcine model of meconium aspiration syndrome. Neonatology.  ISSN 1661-7800.  105(2), s 128- 135 . doi: 10.1159/000356065
  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2014). Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology.  ISSN 0022-1767.  192(6), s 2837- 2845 . doi: 10.4049/jimmunol.1302484

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  • Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegaard, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia & Espevik, Terje (2017). The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes.
  • Christiansen, Dorte; Skjeflo, Espen Waage; Landsem, Anne; Dammen Mathisen, Monica; Fure, Hilde; Stenvik, Jørgen; Woodruff, Trent; Espevik, Terje & Mollnes, Tom Eirik (2016). The effect of combined inhibition of C5aR1 and CD14 on phagocytosis of E. coli in human whole blood .
  • Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari (2016). Cholesterol crystals induce coagulation activation in a complement-dependent manner.
  • Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje & Rokstad, Anne Mari (2016). Cholesterol crystals induce coagulation activation in a complement-dependent manner.
  • Meroni, P.L.; Macor, P.; Durigutto, P; De Maso, L; Gerosa, M; Ferraresso, M; Borghi, MO; Mollnes, Tom Eirik & Tedesco, F. (2016). Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery. Blood.  ISSN 0006-4971. . doi: 10.1182/blood-2015-09-672139
  • Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia & Espevik, Terje (2016). The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes.
  • Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia & Espevik, Terje (2016). The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology.  ISSN 0171-2985.
  • Siljan, William; Holter, Jan Cato; Nymo, Ståle Haugset; Schjalm, Camilla; Müller, Fredrik; Jenum, Pål; Husebye, Einar; Ueland, Thor; Aukrust, Pål; Mollnes, Tom Eirik & Heggelund, Lars (2016). Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome. Journal of Infection.  ISSN 0163-4453.  73(4), s 383- 386 . doi: 10.1016/j.jinf.2016.07.011
  • Stenvik, Jørgen; Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik & Espevik, Terje (2016). TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-b Production via a TAK1–IKKb–IRF5 Signaling Pathway.
  • Wyller, Vegard Bruun; Reme, Silje & Mollnes, Tom Eirik (2016). Kronisk utmattelsessyndrom/myalgisk encefalopati - sykdomsmekanismer, diagnostikk og behandling. Fysioterapeuten.  ISSN 0016-3384.  83(2), s 24- 27
  • Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari; Nymo, Stig Haugset; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2015). Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation.
  • Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Nymo, Stig; Ryan, Liv; Bakke, Siril Skaret; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2015). Cholesterol crystals activate the complement system to induce crystal phagocytosis and inflammation.
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2015). β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION.
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Mollnes, Tom Eirik; Latz, Eicke & Espevik, Terje (2015). Beta-cyclodextrin reduces cholesterol crystal-induced inflammation through modulating complement activation.
  • Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Stenvik, Jørgen & Espevik, Terje (2015). TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages.
  • Nilsson, Bo; Ekdahl, Kristina Nilsson; Kemper, Claudia & Mollnes, Tom Eirik (2015). Preface. Molecular Immunology.  ISSN 0161-5890.  67(1), s 1- 2 . doi: 10.1016/j.molimm.2015.04.006
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne; Berge, Rolf Kristian; Trøseid, Marius; Tasken, Kjetil & Dyrhol-Riise, Anne Ma (2015). Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • Volokhina, Elena B.; Bergseth, Grethe; van de Kar, Nicole C.A.J.; van den Heuvel, Lambertus P. & Mollnes, Tom Eirik (2015). Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo. Blood.  ISSN 0006-4971.  126(2), s 278- 279 . doi: 10.1182/blood-2015-03-637645
  • Wyller, Vegard Bruun; Reme, Silje & Mollnes, Tom Eirik (2015). Kronisk utmattelsessyndrom/myalgisk encefalopati – sykdomsmekanismer, diagnostikk og behandling. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  135(23/24), s 2172- 2175 . doi: 10.4045/tidsskr.15.1180
  • Bergseth, Grethe; Ludviksen, Judith K; Kirschfink, Michael; Giclas, Patricia C.; Nilsson, Bo & Mollnes, Tom Eirik (2014). Corrigendum to "An international serum standard for application in assays to detect human complement activation products" [Mol. Immunol. 56 (2013) 232-239]. Molecular Immunology.  ISSN 0161-5890.  60(2), s 115 . doi: 10.1016/j.molimm.2014.04.008
  • Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2014). Cholesterol crystals induce complement-dependent inflammasome activation.
  • Martinez, Priscilla; Neupane, Sudan Prasad; Lien, Lars; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut & Bramness, Jørgen Gustav (2014). Alcohol use severity may attenuate elevated cytokine levels associated with depression in Nepalese alcohol-use disorder patients.
  • Neupane, Sudan Prasad; Lien, Lars; Martinez, Priscilla; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut & Bramness, Jørgen Gustav (2014). Circulatory cytokine levels in Nepalese alcohol-use disorder patients with and without major depression.
  • Rokstad, Anne Mari; Hamad, Shamal; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Ørning, Mathias Pontus; Lacík, Igor; Ryan, Liv; Mollnes, Tom Eirik; Espevik, Terje & Brekke, Ole Lars (2014). Initial inflammatory and haemostatic mechanisms induced by endogenous and bioartificial surfaces in a whole blood model.
  • Rokstad, Anne Mari; Ørning, Mathias Pontus; Hamad, Shamal; Hoem, Kine Samseth; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Lacík, Igor; Mollnes, Tom Eirik; Brekke, Ole Lars & Espevik, Terje (2014). Inflammatory and hemostatic activation induced by alginate microcapsules reveals novel mechanisms underlying their biocompatibility.

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Published Apr. 13, 2011 2:55 PM - Last modified Jan. 23, 2017 8:30 AM

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