William Edward Louch

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Visiting address Kirkeveien 166 Bygg 7 0450 OSLO
Postal address Postboks 4956 Nydalen 0424 OSLO

Publications

  • Edwards, Andrew & Louch, William Edward (2017). Species-dependent mechanisms of cardiac arrhythmia: A cellular focus. Clinical Medicine Insights: Cardiology.  ISSN 1179-5468.  11 . doi: 10.1177/1179546816686061
  • Gattoni, Sara; Røe, Åsmund Treu; Aronsen, Jan Magnus; Sjaastad, Ivar; Louch, William Edward; Smith, Nicolas P. & Niederer, Steven A. (2017). Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding. Journal of Physiology.  ISSN 0022-3751.  595(12), s 3867- 3889 . doi: 10.1113/JP273879
  • Hafver, Tandekile Lubelwana; Wanichawan, Pimthanya; Manfra, Ornella; De Souza, Gustavo Antonio; Lunde, Marianne; Martinsen, Marita; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2017). Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1). Proteomics.  ISSN 1615-9853.  17(17-18) . doi: 10.1002/pmic.201600417
  • Maleckar, Mary Margot Catherine; Edwards, Andrew; Louch, William Edward & Lines, Glenn Terje (2017). Studying dyadic structure-function relationships: A review of current modeling approaches and new insights into Ca2+(mis)handling. Clinical Medicine Insights: Cardiology.  ISSN 1179-5468.  11, s 1- 11 . doi: 10.1177/1179546817698602
  • Manfra, Ornella; Frisk, Michael & Louch, William Edward (2017). Regulation of cardiomyocyte T-tubular structure: opportunities for therapy. Current Heart Failure Reports.  ISSN 1546-9530.  14(3), s 167- 178 . doi: 10.1007/s11897-017-0329-9
  • Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar & Finsen, Alexandra (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports.  ISSN 2211-1247.  18, s 82- 92 . doi: 10.1016/j.celrep.2016.12.009
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune Forstrøm; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Sjaastad, Ivar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2017). Glycosyalted chromogranin A in heart faiure. Implications for processing and cardiomyocyte calcium homeostasis. Circulation: Heart Failure.  ISSN 1941-3289.  10:e003675(2) . doi: 10.1161/CIRCHEARTFAILURE.116.003675
  • Røe, Åsmund Treu; Aronsen, Jan Magnus; Skårdal, Kristine; Hamdani, Nazha; Linke, Wolfgang A.; Danielsen, Håvard Emil; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2017). Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovascular Research.  ISSN 0008-6363.  113(10), s 1161- 1172 . doi: 10.1093/cvr/cvx087
  • Røe, Åsmund Treu; Sjaastad, Ivar & Louch, William Edward (2017). Heart failure with preserved ejection fraction. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(18) . doi: 10.4045/tidsskr.16.1068
  • Aronsen, Jan Magnus; Louch, William Edward & Sjaastad, Ivar (2016). Cardiomyocyte Ca2+ dynamics: Clinical perspectives. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  50(2), s 65- 77 . doi: 10.3109/14017431.2015.1136079
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Sejersted, Ole M; Christensen, Geir Arve; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research.  ISSN 0008-6363. . doi: 10.1093/cw111
  • Gattoni, Sara; Røe, Åsmund Treu; Frisk, Michael; Louch, William Edward; Niederer, Steven A. & Smith, Nicolas P. (2016). The calcium-frequency response in the rat ventricular myocyte: an experimental and modeling study. Journal of Physiology.  ISSN 0022-3751.  594(15), s 4193- 4224 . doi: 10.1113/JP272011
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Per Kristian; Lunde, Marianne; Martinsen, Marita; Enger, Ulla Helene; Fuller, William; Sjaastad, Ivar; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2016). Protein phosphatase 1c associated with the cardiac sodium calcium exchanger 1 regulates its activity by dephosphorylating Serine 68-phosphorylated phospholemman. Journal of Biological Chemistry.  ISSN 0021-9258.  291(9), s 4561- 4579 . doi: 10.1074/jbc.M115.677898 Show summary
  • Hodne, Kjetil; Lipsett, David Bruce & Louch, William Edward (2016). Gene Transfer in Isolated Adult Cardiomyocytes. Methods in Molecular Biology.  ISSN 1064-3745.  1521, s 169- 182 . doi: 10.1007/978-1-4939-6588-5_11
  • Louch, William Edward; Frisk, Michael & Eggart, Benjamin (2016). High-speed recording of cardiomyocyte calcium and contraction. Ultra-low calcium signaling measured at high speeds. Optik & Photonik.  ISSN 2191-1975.  4
  • Wanichawan, Pimthanya; Hodne, Kjetil; Hafver, Tandekile Lubelwana; Lunde, Marianne; Martinsen, Marita; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2016). Development of a high affinity peptide that prevents phospholemman (PLM) inhibition of the sodium-calcium exchanger 1 (NCX1). Biochemical Journal.  ISSN 0264-6021.  473(15), s 2413- 2423 . doi: 10.1042/BCJ20160465
  • Aronsen, Jan Magnus; Skogestad, Jonas; Lewalle, Alexandre; Louch, William Edward; Hougen, Karina; Stokke, Mathis Korseberg; Swift, Fredrik; Niederer, Steven; Smith, Nic P.; Sejersted, Ole M & Sjaastad, Ivar (2015). Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+ ,K+-ATPase α2 activity. Journal of Physiology.  ISSN 0022-3751.  593(6), s 1509- 1521 . doi: 10.1113/jphysiol.2014.279893
  • Clancy, Colleen E; Chen-Izu, Ye; Bers, Donald M; Belardinelli, Luiz; Boyden, Penelope A; Csernoch, Laszlo; Despa, Sanda; Fermini, Bernard; Hool, Livia C; Izu, Leighton; Kass, Robert S; Lederer, W. Jonathan; Louch, William Edward; Maack, Christoph; Matiazzi, Alicia; Qu, Zhilin; Rajamani, Sridharan; Rippinger, Crystal M; Sejersted, Ole M; O'Rourke, Brian; Weiss, James N.; Varro, Andras & Zaza, Antonio (2015). Deranged sodium to sudden death. Journal of Physiology.  ISSN 0022-3751.  593(6), s 1331- 1345 . doi: 10.1113/jphysiol.2014.281204
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Boye, Sigurd; Unger, Andreas; Brorson, Sverre Henning; Sjaastad, Ivar; Tønnessen, Theis; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2015). Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart. Cardiovascular Research.  ISSN 0008-6363.  106, s 217- 226 . doi: 10.1093/cvr/cvv002
  • Louch, William Edward; Koivumaki, Jussi & Tavi, Pasi (2015). Calcium signalling in developing cardiomyocytes: Implications for model systems and disease. Journal of Physiology.  ISSN 0022-3751.  593(5), s 1047- 1063 . doi: 10.1113/jphysiol.2014.274712
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. Journal of the American College of Cardiology.  ISSN 0735-1097.  65(4), s 339- 351 . doi: 10.1016/j.jacc.2014.10.065
  • Palecek, Tomas; Fikrle, Michal; Nemecek, Eduard; Bauerova, Lenka; Kuchynka, Petr; Louch, William Edward; Spicka, Ivan & Rysava, Romana (2015). Contemporary treatment of amyloid heart disease. Current pharmaceutical design.  ISSN 1381-6128.  21, s 491- 506
  • Røe, Åsmund Treu; Frisk, Michael & Louch, William Edward (2015). Targeting cardiomyocyte Ca2+ homeostasis in heart failure. Current pharmaceutical design.  ISSN 1381-6128.  21(4), s 431- 448 . doi: 10.2174/138161282104141204124129
  • Tinholt, Mari; Stavik, Benedicte; Louch, William Edward; Carlson, Cathrine Rein; Sletten, Marit; Ruf, Wolfram; Skretting, Grethe; Sandset, Per Morten & Iversen, Nina (2015). Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells. PLoS ONE.  ISSN 1932-6203.  10(1) . doi: 10.1371/journal.pone.0117404
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  306(7), s H1018- H1024 . doi: 10.1152/ajpheart.00741.2013
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135. . doi: 10.1152/ajpheart.00741.2013 Full text in Research Archive.
  • Frisk, Michael; Koivumaki, Jussi; Norseng, Per Andreas; Maleckar, Mary; Sejersted, Ole M & Louch, William Edward (2014). Variable t-tubule organization and Ca2+ homeostasis across the atria. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  307(4), s H609- H620 . doi: 10.1152/ajpheart.00295.2014
  • Land, Sander; Niederer, Steven A.; Louch, William Edward; Røe, Åsmund Treu; Aronsen, Jan Magnus; Stuckey, Daniel J; Sikkel, MB; Tranter, M.; Lyon, Alexander R.; Harding, Sian E. & Smith, Nic P. (2014). Computational modelling of Takotsubo cardiomyopathy: Effect of spatially varying beta-adrenergic stiumlation in the rat left ventricle. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  307(10), s H1487- H1496 . doi: 10.1152/ajpheart.00443.2014 Show summary
  • Louch, William Edward; Land, Sander & Niederer, Steven (2014). Strange bedfellows: biologists and mathematical modellers tie the knot on cardiomyoctyes calcium homeostasis. Drug Discovery Today : Disease Models.  ISSN 1740-6757.  14, s 11- 16 . doi: 10.1016/j.ddmod.2014.05.001
  • Misceo, Doriana; Holmgren, Asbjørn; Louch, William Edward; Holme, Pål Andre; Mizobuchi, Masahiro; Morales, Raul J.; De Paula, André Maues; Stray-Pedersen, Asbjørg; Lyle, Robert; Dalhus, Bjørn; Christensen, Geir Arve; Stormorken, Helge; Tjønnfjord, Geir Erland & Frengen, Eirik (2014). A Dominant STIM1 Mutation Causes Stormorken Syndrome. Human Mutation.  ISSN 1059-7794.  35(5), s 556- 564 . doi: 10.1002/humu.22544
  • Nordbø, Øyvind; Lamata, P.; Land, Sander; Niederer, Steven A.; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Martens, Harald; Gjuvsland, Arne Bjørke; Tøndel, Kristin; Torp, Hans; Lohezic, M; Schneider, Jürgen; Remme, Espen W.; Smith, Nicolas P; Omholt, Stig W & Vik, Jon Olav (2014). A computational pipeline for quantification of mouse myocardial stiffness parameters. Computers in Biology and Medicine.  ISSN 0010-4825.  53, s 65- 75 . doi: 10.1016/j.compbiomed.2014.07.013 Full text in Research Archive. Show summary
  • Wanichawan, Pimthanya; Lubelwana, Tandekile; Hodne, Kjetil; Aronsen, Jan Magnus; Lunde, Ida Gjervold; Dalhus, Bjørn; Lunde, Marianne; Kvaløy, Heidi; Louch, William Edward; Tønnessen, Theis; Sjaastad, Ivar; Sejersted, Ole M & Carlson, Cathrine Rein (2014). Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure. Journal of Biological Chemistry.  ISSN 0021-9258.  289(49), s 33984- 33998 . doi: 10.1074/jbc.M114.602581
  • Land, Sander; Louch, William Edward; Niederer, Steven A.; Aronsen, Jan Magnus; Christensen, Geir Arve; Sjaastad, Ivar; Sejersted, Ole M & Smith, Nicolas P. (2013). Beta-Adrenergic Stimulation Maintains Cardiac Function in Serca2 Knockout Mice. Biophysical Journal.  ISSN 0006-3495.  104(6), s 1349- 1356 . doi: 10.1016/j.bpj.2013.01.042
  • Land, Sander; Niederer, Steven A.; Louch, William Edward; Sejersted, Ole M & Smith, Nicolas P. (2013). Integrating multi-scale data to create a virtual physiological mouse heart. Interface Focus.  ISSN 2042-8898.  3(2) . doi: 10.1098/rsfs.2012.0076

View all works in Cristin

  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Dispersion of ryanodine receptor clusters disrupts calcium sparks in failing cardiomyocyte.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Super-resolution imaging reveals dispersion of ryanodine receptor clusters during heart failure.
  • Li, Jia; Frisk, Michael; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Regional activation of the Frank-Starling mechanism within the cardiomyocyte.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2016). BIN1 triggers t-tubule development in cardiomyocytes.
  • Marshall, Serena; Børstad, Mira Halvorsen; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B; Espe, Emil Knut Stenersen; Zhang, Lili; Louch, William Edward; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). SERCA2 activation is beneficial in chronic heart disease.
  • Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five; Aakhus, Svend; Lunde, Ida Gjervold; Almaas, Vibeke; Gullestad, Lars; Sjaastad, Ivar; Tønnessen, Theis; Sejersted, Ole M; Norseng, Per Andreas; Christensen, Geir Arve & Louch, William Edward (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts diastolic Calcium homeostasis of the cardiomyocyte.
  • Shen, Xin; Kolstad, Terje R Selnes & Louch, William Edward (2016). Quantitative localization of Cardiac RyRs by 3D-dSTORM super-resolution imaging.
  • Tazmini, Kiarash; Frisk, Michael; Lipsett, David Bruce; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Erik & Louch, William Edward (2016). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Wanichawan, Pimthanya; Hafver, Tandekile Lubelwana; Lunde, Marianne; Martinsen, Marita; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2016). The N-terminal membrane occupation and recognition nexus (MORN) domains of junctophilin-2 bind to Na+/Ca2+ exchanger.
  • Curran, James & Louch, William Edward (2015). Linking ryanodine receptor Ca2+ leak and Na+ current in heart: A day in the life of flecainide. Acta Physiologica.  ISSN 1748-1708.  214, s 300- 302
  • Curran, Jerry & Louch, William Edward (2015). Linking ryanodine receptor Ca2+ leak and Na+ current in heart: a day in the life of flecainide. Acta Physiologica.  ISSN 1748-1708.  214(3), s 300- 302 . doi: 10.1111/apha.12526
  • Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five; Almaas, Victor; Gullestad, Lars; Christensen, Geir Arve; Aakhus, Svend; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Christensen, Geir Arve; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2015). Ventricular wall stress predicts disruption of cardiomyocyte t-tubule structure and Ca2+ homeostasis across the infarcted heart. Biophysical Journal.  ISSN 0006-3495.  108, s 106a
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Per Kristian; Martinsen, Marita; Enger, Ulla Helene; Fuller, William; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2015). PP1 associated with cardiac NCX1 regulates exchange activity by dephosphorylating pSer-68-PLM.
  • Hodne, Kjetil; Wanichawan, Pimthanya; Lubelwana, Tandekile; Louch, William Edward; Lunde, Marianne; Mathisen, Marita; Sejersted, Ole M & Carlson, Cathrine Rein (2015). Liberation of Pser68-Plm inhibition of NCX1 by an optimized anchoring disruptor peptide. Biophysical Journal.  ISSN 0006-3495.  108, s 434a- 434a
  • Kolstad, Terje R Selnes; MacQuaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Kolstad, Terje R Selnes; Stokke, Mathis Korseberg; Stang, Espen; Brorson, Sverre Henning; Louch, William Edward & Sejersted, Ole M (2015). Serca located in the junctional SR shapes calcium release in cardiac myocytes. Biophysical Journal.  ISSN 0006-3495.  108, s 503a- 503a
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (BIN1) initiates t-tubule Growth during Cardiac Development and disease. Biophysical Journal.  ISSN 0006-3495.  108, s 130a- 130a
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sjaastad, Ivar; Wasserstrom, Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
  • Louch, William Edward (2015). Transverse tubules and cardiac calcium handling.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Edwards, Andrew; Landsverk, Ole J. B.; Johansen, Rune Forstrøm; Moe, Morten Kaare; Bjørås, Magnar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin,a novel endogenous CaMKII inhibitor, augments cardiomyocyte Calcium handling and inhibits arrhythmogenic Calcium release. Biophysical Journal.  ISSN 0006-3495.  108, s 340a- 340a
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune F.; Jarstadmarken, Hilde; Bjørås, Magnar; Sjaastad, Ivar; Høiseth, Arne Didrik; Brynildsen, Jon; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Enhanced myocardial chromogranin A glycosylation in acute heart failure: reduced processing and potential impact on cardiomyocyte calcium homeostasis.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Johansen, Rune F.; Stridsberg, Mats; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Chromogranin A is a potent prognostic biomarker in acute heart failure, and its fragment catestatin regulates cardiomyocyte calcium homeostasis by CaMKII inhibition.
  • Ottesen, Anett Hellebø; Laver, Derek; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin a novel endogenous CaMKIIð inhibitor, inhibits Ca2+ dependent arrhythmogenesis.
  • Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Regulation of cardiomyocyte t-tubule organization and density by ventricular wall stress. Biophysical Journal.  ISSN 0006-3495.  108, s 443a- 443a
  • Tazmini, Kiarash; Frisk, Michael; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Eric & Louch, William Edward (2015). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Wanichawan, Pimthanya; Hodne, Kjetil; Hafver, Tandekile Lubelwana; Lunde, Marianne; Martinsen, Marita; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2015). Development of a high affinity phospholemman binding peptide that reverses phosphorylated serine 68 phospholemman inhibition of the cardiac sodium-calcium exchanger 1.
  • Frisk, Michael; Espe, Emil Knut Stenersen; Røe, Åsmund Treu; Aronsen, Jan Magnus; Enger, Ulla Helene; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2014). In vivo strain measurements predict regional disruption of cardiomyocyte structure and Ca2+ homeostasis during heart failure..
  • Frisk, Michael; Espe, Emil Knut Stenersen; Røe, Åsmund Treu; Aronsen, Jan Magnus; Enger, Ulla Helene; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2014). Regional left ventricular strain and wall stress predict cardiomyocyte T-tubular structure and Ca2+ homeostasis following myocardial infarction.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Boye, Sigurd; Unger, Andreas; Linke, Wolfgang A.; Brorson, Sverre Henning; Sjaastad, Ivar; Tønnessen, Theis; Gomez, Maria F. & Christensen, Geir Arve (2014). Syndecan-4 is a key determinant of collagen cross-linking and myocardial stiffness in the pressure-overloaded heart.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Tønnessen, Theis; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2014). Syndecan-4 promotes myocardial stiffness by regulating collagen expression and cross-linking in response to pressure overload. The FASEB Journal.  ISSN 0892-6638.  28
  • Hodne, Kjetil; Wanichawan, Pimthanya; Hafver, Tandekile Lubelwana; Aronsen, Jan Magnus; Lunde, Ida Gjervold; Lunde, Marianne; Kvaløy, Heidi; Tønnessen, Theis; Sjaastad, Ivar; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2014). Identification and functional role of calpain cleavage site in Na+-Ca2+ exchanger 1 (NCX1). Biophysical Journal.  ISSN 0006-3495.  106, s 762a
  • Kolstad, Terje R Selnes; Stokke, Mathis Korseberg; Stang, Espen; Brorson, Sverre Henning; Christensen, Geir Arve; Louch, William Edward & Sejersted, Ole M (2014). SERCA localized near the dyad regulates calcium release in cardiac myocytes.
  • Kolstad, Terje R Selnes; Stokke, Mathis Korseberg; Stang, Espen; Brorson, Sverre Henning; Louch, William Edward & Sejersted, Ole M (2014). SERCA localized near the dyad regulates calcium release in cardiac myoctyes.
  • Kolstad, Terje R Selnes; Stokke, Mathis Korseberg; Stang, Espen; Brorson, Sverre Henning; Louch, William Edward & Sejersted, Ole M (2014). SERCA localized near the dyad regulates calcium release in cardiac myocytes.
  • Lipsett, David Bruce; Frisk, Michael; Hodne, Kjetil; Singh, Neha; Nygård, Ståle; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, Andrew J.; Christensen, Geir Arve & Louch, William Edward (2014). B1N1 controls longitudinal T-tubule growth in cardiomyocytes during development and disease.
  • Lipsett, David Bruce; Singh, Neha; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2014). Bridging integrator 1 (BIN1)-induced t-tubule formation in cardiomyocytes. Biophysical Journal.  ISSN 0006-3495.  106(2), s 772a
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Høiseth, Arne Didrick; Brynildsen, Jon; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Chromogranin A directly modifies cardiomyocyte Ca2+ homeostasis via CaMKII inhibition and is a strong prognostic biomarker in acute heart failure.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Stridsberg, Mats; Høiseth, Arne Didrik; Brynildsen, Jon; Moe, Morten Kaare; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Chromogranin A is a potent risk marker in acute heart failure and directly associated with cardiomyocyTe Ca2+ handling. European Heart Journal.  ISSN 0195-668X.  35, s 328- 328
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Secretoneurin provides independent prognostic information in patients with heart failure and cardiac arrest, and has a direct inhibitory effect on diastolic Ca2+ leak and arrhythmogenic Ca2+ waves via CaMKII inhibition. Circulation Research.  ISSN 0009-7330.  115
  • Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2014). Regulation of cardiomyocyte t-tubule organization by preload and afterload.
  • Røe, Åsmund Treu; Aronsen, Jan Magnus; Frisk, Michael; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2014). Active and passive stiffness in a hypertrophic rat model of diastolic dysfunction.
  • Røe, Åsmund Treu; Aronsen, Jan Magnus; Frisk, Michael; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2014). Compensatory alterations in cardiomyocytes Ca2+ homeostasis during aortic stenosis.
  • Tazmini, Kiarash; Frisk, Michael; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Erik & Louch, William Edward (2014). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Johansen, Rune forstrom; Moe, Morten; Høiseth, Arne Didrik; Jarstadmarken, Hilde o.; Nygård, Ståle; Bjørås, Magnar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2013). Secretoneurin is a novel endogenous CaMKII inhibitor that regulates cardiomyocyte calcium handling and is closely associated with mortality in patients with acute heart failure. Circulation.  ISSN 0009-7322.  128
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Johansen, Rune forstrom; Moe, Morten; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2013). Secretoneurin regulates cardiomyocyte calcium homeostasis CaMKIIinhibition and is a potent marker of mortality in patients with acute heart failure.
  • Frisk, Michael; Jølle, Guro Five; Lunde, Ida Gjervold; Skrbic, Biljana; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2013). Aortic Stenosis Triggers T-Tubule Growth in Human and Murine Cardiomyocytes. Biophysical Journal.  ISSN 0006-3495.  104(2), s 603A- 603A
  • Frisk, Michael; Jølle, Guro Five; Lunde, Ida Gjervold; Skrbic, Biljana; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2013). Aortic stenosis triggers t-tubule growth in human and murine cardiomyocytes.
  • Frisk, Michael; Norseng, Per Andreas; Sejersted, Ole M & Louch, William Edward (2013). Variable t-tubule density and Ca2+ homeostasis across the atria.
  • Frisk, Michael; Norseng, Per Andreas; Sejersted, Ole M & Louch, William Edward (2013). Variable t-tubule density and calcium homeostasis across the atria. Circulation.  ISSN 0009-7322.  128
  • Frisk, Michael; Norseng, Per Andreas; Sejersted, Ole M & Louch, William Edward (2013). Variable t-tubule density and calcium homeostasis across the atria.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Unger, Andreas; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2013). Syndecan-4 regulates myocardial stiffness in response to mechanical stress by regulating extracellular matrix composition through myofibroblast differentiation. European Journal of Heart Failure. Supplements.  ISSN 1567-4215.  12, s S68- S68
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Tønnessen, Theis; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Boye, Sigurd; Brorson, Sverre Henning; Unger, Andreas; Linke, Wolfgang; Gomez, Maria & Christensen, Geir Arve (2013). Syndecan-4 promotes myocardial stiffness by regulating myofibroblast differentiation and extracellular matrix structure in response to pressure overload.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Tønnessen, Theis; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Boye, Sigurd; Brorson, Sverre-Henning; Unger, Andreas; Linke, Wolfgang A.; Gomez, Maria & Christensen, Geir Arve (2013). Syndecan-4 regulates myocardial stiffness by inducing myofibroblast differentiation, extracellular matrix production and collagen cross-linking in response to pressure overload. Circulation.  ISSN 0009-7322.  128
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Tønnessen, Theis; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Unger, Andreas; Linke, Wolfgang A.; Gomez, Maria & Christensen, Geir Arve (2013). Syndecan-4 regulates myocardial stiffness by inducing myofibroblast differentiation, extracellular matrix production and collagen cross-linking in response to pressure overload.
  • Lipsett, David Bruce; Singh, Neha; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2013). Bridging integrator1(BIN1)-induced t-tubule formation in cardiomyocytes.

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Published Dec. 10, 2015 3:00 PM