Naltrexone as a relapse prophylaxis in opioid dependence
Naltrexone is a drug that blocks heroin and other opioids, which may help opioid-dependent patients to maintain their desire for heroin abstinence.
About the project
Remaining abstinent from heroin without the use of methadone or other OMT-drugs is very difficult in the long-term.
This study compares a long-acting intramuscular formulation of naltrexone with the current first choice in OMT, buprenorphine-naloxone in an exploratory, randomized multicentre study.
The study is led by Lars Tanum and Nikolaj Kunøe in cooperation with the Norwegian Institute of Public Health (Asbjørg Christophersen), Oslo University Hospital, Akershus University Hospital, Østfold Hospital (Arild Schillinger), Stavanger University Hospital/KORFOR (Sverre Nesvåg and Kristian Oppedal Larsen), Health Bergen (Ola Jøsendal and Arild Opheim), Sørlandet Hospital, Kristiansand (Bjørg Hjerkinn), Vestfold Hospital (Jens Egeland).