Øystein Fodstad

Professor emeritus - Kreftklinikken
Bilde av Øystein Fodstad
English version of this page
Telefon +47-22781402
Brukernavn
Besøksadresse Postboks 4953 Nydalen None 0424 OSLO
Andre tilknytninger Institutt for kreftforskning

Publikasjoner

  • Frøysnes, Ida Storhaug; Andersson, Yvonne; Larsen, Stein Gunnar; Davidson, Ben; Øien, Janne-Merete Torset; Olsen, Kari Hauge; Giercksky, Karl-Erik; Julsrud, Lars; Fodstad, Øystein; Dueland, Svein & Flatmark, Kjersti (2017). Novel treatment with intraperitoneal MOC31PE immunotoxin in colorectal peritoneal metastasis: results from the ImmunoPeCa Phase 1 Trial. Annals of Surgical Oncology.  ISSN 1068-9265.  24(7), s 1916- 1922 . doi: 10.1245/s10434-017-5814-6
  • Lim, Sangbin; Phillips, Joshua B.; da Silva, Luciana Madeira; Zhou, Ming; Fodstad, Øystein; Owen, Laurie B. & Tan, Ming (2017). Interplay between immune checkpoint proteins and cellular metabolism. Cancer Research.  ISSN 0008-5472.  77(6), s 1245- 1249 . doi: 10.1158/0008-5472.CAN-16-1647
  • Wang, Mengyu; Nestvold, Janne M.; Rekdal, Øystein; Kvalheim, Gunnar & Fodstad, Øystein (2017). A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties. Experimental Cell Research.  ISSN 0014-4827.  352(2), s 218- 224 . doi: 10.1016/j.yexcr.2017.02.005
  • Eide, Nils; Garred, Øystein; Beiske, Klaus & Fodstad, Øystein (2016). Bilateral uveal melanomas with different gene expression detected with 7 years interval. Acta Ophthalmologica.  ISSN 1755-375X.  94(1), s 99- 102 . doi: 10.1111/aos.12857
  • Lim, Sangbin; Liu, Hao; da Silva, Luciana Madeira; Arora, Ritu; Liu, Zixing; Phillips, Joshua B.; Schmitt, David C.; Vu, Tung; McClellan, Steven; Lin, Yingfeng; Lin, Wensheng; Piazza, Gary A.; Fodstad, Øystein & Tan, Ming (2016). Immunoregulatory protein B7-H3 reprograms glucose metabolism in cancer cells by ROS-mediated stabilization of HIF1a. Cancer Research.  ISSN 0008-5472.  76(8), s 2231- 2242 . doi: 10.1158/0008-5472.CAN-15-1538
  • Nunes-Xavier, Caroline Elisabeth; Flem Karlsen, Karine; Tekle, Christina; Pedersen, Cathrine; Øyjord, Tove Ragnhild; Hongisto, Vesa; Nesland, Jahn M; Tan, Ming; Sahlberg, Kristine Kleivi & Fodstad, Øystein (2016). Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors. OncoTarget.  ISSN 1949-2553.  7(6), s 6891- 6901 . doi: 10.18632/oncotarget.6902 Fulltekst i vitenarkiv
  • Rud, Ane Kristine Kongsgaard; Pedersen, Kjetil Boye; Fodstad, Øystein; Juell, Siri; Jørgensen, Lars Hilmar; Solberg, Steinar; Helland, Åslaug; Brustugun, Odd Terje & Mælandsmo, Gunhild (2016). Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer. Diagnostic Pathology.  ISSN 1746-1596.  11(50) . doi: 10.1186/s13000-016-0504-4 Fulltekst i vitenarkiv
  • Sas-Chen, Aldema; Aure, Miriam Ragle; Leibovich, Limor; Carvalho, Silvia; Enuka, Yehoshua; Körner, Cindy; Polycarpou-Schwarz, Maria; Lavi, Sara; Nevo, Nava; Kuznetsov, Yuri; Yuan, Justin; Azuaje, Francisco; Ulitsky, Igor; Diederichs, Sven; Wiemann, Stefan; Yakhini, Zohar; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise; Yarden, Yosef; Sauer, Torill; Geisler, Jürgen; Hofvind, Solveig; Bathen, Tone Frost; Borgen, Elin; Engebråten, Olav; Fodstad, Øystein; Garred, Øystein; Geitvik, Gry; Kåresen, Rolf; Naume, Bjørn; Mælandsmo, Gunhild; Russnes, Hege Elisabeth Giercksky; Schlichting, Ellen; Sørlie, Therese; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Skjerven, Helle & Fritzman, Britt (2016). LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  8(9), s 1052- 1064 . doi: 10.15252/emmm.201606198 Fulltekst i vitenarkiv
  • Andersson, Yvonne; Engebråten, Olav; Juell, Siri; Aamdal, Steinar; Brunsvig, Paal Fr.; Fodstad, Øystein & Dueland, Svein (2015). Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin. British Journal of Cancer.  ISSN 0007-0920.  113(11), s 1548- 1555 . doi: 10.1038/bjc.2015.380
  • Eide, Nils; Faye, Ragnar Solberg; Høifødt, Hanne Kleppe; Sandstad, Berit; Qvale, Geir Aksel; Faber, Rowan Thomas; Jebsen, Peter Wilhelm; Kvalheim, Gunnar & Fodstad, Øystein (2015). Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: A paradox. Acta Ophthalmologica.  ISSN 1755-375X.  93(1), s 59- 66 . doi: 10.1111/aos.12462
  • Hoshino, Ayuko; Costa-Silva, Bruno; Shen, Tang-Long; Rodrigues, Goncalo; Hashimoto, Ayako; Tesic Mark, Milica; Molina, Henrik; Kohsaka, Shinji; Di Giannatale, Angela; Ceder, Sophia; Singh, Swarnima; Williams, Caitlin; Soplop, Nadine; Uryu, Kunihiro; Pharmer, Lindsay; King, Tari; Bojmar, Linda; Davies, Alexander E.; Ararso, Yonathan; Zhang, Tuo; Zhang, Haiying; Hernandez, Jonathan; Weiss, Joshua M.; Dumont-Cole, Vanessa D.; Kramer, Kimberly; Wexler, Leonard H; Narendran, Aru; Schwartz, Gary K.; Healey, John H.; Sandström, Per; Labori, Knut Jørgen; Kure, Elin H.; Grandgenett, Paul M.; Hollingsworth, Michael A.; De Sousa, Maria; Kaur, Sukhwinder; Jain, Maneesh; Mallya, Kavita; Batra, Surinder K.; Jarnagin, William R; Brady, Mary S.; Fodstad, Øystein; Muller, Volkmar; Pantel, Klaus; Minn, Andy J.; Bissell, Mina J.; Garcia, Benjamin A.; Kang, Yibin; Rajasekhar, Vinagolu K.; Ghajar, Cyrus M.; Matei, Irina; Peinado, Hector; Bromberg, Jacqueline & Lyden, David (2015). Tumour exosome integrins determine organotropic metastasis. Nature.  ISSN 0028-0836.  527(7578), s 329- 335 . doi: 10.1038/nature15756
  • Srivastava, Sanjeev K.; Bhardwaj, Ashwani; Arora, Sumit; Tyagi, Nikhil; Singh, Ajay P.; Carter, James E.; Scammell, Jonathan G.; Fodstad, Øystein & Singh, Seema (2015). Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis. British Journal of Cancer.  ISSN 0007-0920.  112, s 1772- 1781 . doi: 10.1038/bjc.2015.154
  • Ingebrigtsen, Vibeke Anett; Boye, Kjetil; Nesland, Jahn M; Nesbakken, Arild; Flatmark, Kjersti & Fodstad, Øystein (2014). B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome. BMC Cancer.  ISSN 1471-2407.  20(14) . doi: 10.1186/1471-2407-14-602
  • Nygren, Marit; Tekle, Christina; Ingebrigtsen, Vibeke Anett; Mäkelä, Rami; Krohn, Marit; Aure, Miriam Ragle; Nunes-Xavier, Caroline Elisabeth; Perälä, Merja; Tramm, Trine; Alsner, Jan; Overgaard, Jens; Nesland, Jahn M; Borgen, Elin; Børresen-Dale, Anne-Lise; Fodstad, Øystein; Sahlberg, Kristine Kleivi & Leivonen, Suvi-Katri (2014). Identifyinig microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c. British Journal of Cancer.  ISSN 0007-0920.  15 . doi: 10.1038/bjc.2014.113
  • Wiiger, Merete Thune; Bideli, Hemaseh; Fodstad, Øystein; Flatmark, Kjersti & Andersson, Yvonne (2014). The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells. Journal of Ovarian Research.  ISSN 1757-2215.  7(1) . doi: 10.1186/1757-2215-7-23
  • Bruheim, Skjalg; Sandvold, Marit Liland; Mælandsmo, Gunhild & Fodstad, Øystein (2013). Antitumor Activity of Elacytarabine Combined with Bevacizumab, Cetuximab and Trastuzumab in Human NSCLC Xenografts. Anticancer Research.  ISSN 0250-7005.  33(9), s 3615- 3621
  • Desai, Shruti; Liu, Zixing; Yao, Jun; Patel, Nishant; Chen, Jieqing; Wu, Yun; Ahn, Erin Eun-Young; Fodstad, Øystein & Tan, Ming (2013). Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7). Journal of Biological Chemistry.  ISSN 0021-9258.  288(13), s 9165- 9176 . doi: 10.1074/jbc.M112.422071
  • Eide, Nils; Høifødt, Hanne Kleppe; Nesland, Jahn M; Faye, Ragnar Solberg; Qvale, Geir Aksel; Faber, Rowan Thomas; Jebsen, Peter Wilhelm; Kvalheim, Gunnar & Fodstad, Øystein (2013). Disseminated tumour cells in bone marrow of patients with uveal melanoma. Acta Ophthalmologica.  ISSN 1755-375X.  91(4), s 343- 348 . doi: 10.1111/j.1755-3768.2012.02449.x
  • Flatmark, Kjersti; Guldvik, Ingrid Jenny; Svensson, Hege Christin; Fleten, Karianne Giller; Flørenes, Vivi Ann; Reed, Wenche; Giercksky, Karl-Erik; Fodstad, Øystein & Andersson, Yvonne (2013). Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies. International Journal of Cancer.  ISSN 0020-7136.  133(6), s 1497- 1506 . doi: 10.1002/ijc.28158
  • Liu, Zixing; Liu, Hao; Desai, Shruti; Schmitt, David; Zhou, Ming; Khong, Hung T.; Klos, Kristine S.; McClellan, Steven; Fodstad, Øystein & Tan, Ming (2013). miR-125b Functions as a Key Mediator for Snail-induced Stem Cell Propagation and Chemoresistance. Journal of Biological Chemistry.  ISSN 0021-9258.  288(6), s 4334- 4345 . doi: 10.1074/jbc.M112.419168
  • Rud, Ane Kristine Kongsgaard; Borgen, Elin; Mælandsmo, Gunhild; Flatmark, Kjersti; Le, Hang Ngoc Thi; Josefsen, Dag; Solvoll, Ingjerd; Schirmer, Cecilie; Helland, Åslaug; Jørgensen, Lars Hilmar; Brustugun, Odd Terje; Fodstad, Øystein & Boye, Kjetil (2013). Clinical significance of disseminated tumour cells in non-small cell lung cancer. British Journal of Cancer.  ISSN 0007-0920.  109(5), s 1264- 1270 . doi: 10.1038/bjc.2013.450
  • Schee, Kristina; Lorenz, Susanne; Worren, Merete Molton; Günther, Clara-Cecilie; Holden, Marit; Hovig, Johannes Eivind; Fodstad, Øystein; Meza, Leonardo Zepeda & Flatmark, Kjersti (2013). Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLoS ONE.  ISSN 1932-6203.  8(6) . doi: 10.1371/journal.pone.0066165
  • Wang, Ping; Suo, Zhenhe; Wang, Mengyu; Høifødt, Hanne Kleppe; Fodstad, Øystein; Gaudernack, Gustav & Kvalheim, Gunnar (2013). In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines. Experimental hematology and oncology.  ISSN 2162-3619.  2(16) . doi: 10.1186/2162-3619-2-16
  • Zhai, Haiyan; Fesler, Andrew; Schee, Kristina; Fodstad, Øystein; Flatmark, Kjersti & Ju, Jingfang (2013). Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer. Clinical colorectal cancer.  ISSN 1533-0028.  12(4), s 261- 266 . doi: 10.1016/j.clcc.2013.06.003
  • Ding, Yan; Liu, Zixing; Desai, Shruti; Zhao, Yuhua; Liu, Hao; Pannell, Lewis K; Yi, Hong; Wright, Elizabeth R; Owen, Laurie B.; Dean-Colomb, Windy; Fodstad, Øystein; Lu, Jianrong; Ledoux, Susan P.; Wilson, Glenn L. & Tan, Ming (2012). Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism. Nature Communications.  ISSN 2041-1723.  3 . doi: 10.1038/ncomms2236
  • Ingebrigtsen, Vibeke Anett; Boye, Kjetil; Tekle, Christina; Nesland, Jahn M; Flatmark, Kjersti & Fodstad, Øystein (2012). B7-H3 expression in colorectal cancer: Nuclear localization strongly predicts poor outcome in colon cancer. International Journal of Cancer.  ISSN 0020-7136.  131(11), s 2528- 2536 . doi: 10.1002/ijc.27566
  • Schee, Kristina; Boye, Kjetil; Abrahamsen, Torveig Weum; Fodstad, Øystein & Flatmark, Kjersti (2012). Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer. BMC Cancer.  ISSN 1471-2407.  12(505) . doi: 10.1186/1471-2407-12-505
  • Tekle, Christina; Nygren, Marit Kveine; Chen, Yih-Wen; Dybsjord, Indrejit; Nesland, Jahn M; Mælandsmo, Gunhild & Fodstad, Øystein (2012). B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes. International Journal of Cancer.  ISSN 0020-7136.  130(10), s 2282- 2290 . doi: 10.1002/ijc.26238
  • Vincent, Andrew J.; Ren, Suping; Harris, Lillianne G.; Devine, Daniel J.; Samant, Rajeev S.; Fodstad, Øystein & Shevde, Lalita A. (2012). Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance NUPR1 and p21 in chemoresistance. FEBS Letters.  ISSN 0014-5793.  586(19), s 3429- 3434 . doi: 10.1016/j.febslet.2012.07.063
  • Bergman, A.M; Adema, A.D.; Balzarini, J.; Bruheim, Skjalg; Fichtner, I.; Noordhuis, P.; Fodstad, Øystein; Myhren, F.; Sandvold, M.L.; Hendriks, H.R. & Peters, G.J. (2011). Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models. Investigational new drugs.  ISSN 0167-6997.  29(3), s 456- 466 . doi: 10.1007/s10637-009-9377-7
  • Bruheim, Skjalg; Kristian, Alexandr; Uenaka, Toshimitsu; Suo, Zhenhe; Tsuruoka, Akihiko; Nesland, Jahn M & Fodstad, Øystein (2011). Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts. International Journal of Cancer.  ISSN 0020-7136.  129(3), s 742- 750 . doi: 10.1002/ijc.25922
  • Flatmark, Kjersti; Borgen, Elin; Nesland, Jahn M; Rasmussen, Heidi; Johannessen, Hans Olaf; Bukholm, Ida Rashida Khan; Rosales, Rocio; Hårklau, Lisbeth; Jacobsen, Hedin Jeffri; Sandstad, Berit; Boye, Kjetil & Fodstad, Øystein (2011). Disseminated tumour cells as a prognostic biomarker in colorectal cancer. British Journal of Cancer.  ISSN 0007-0920.  104(9), s 1434- 1439 . doi: 10.1038/bjc.2011.97
  • Hjortland, Geir Olav; Meza, Leonardo Zepeda; Beiske, Klaus; Ree, Anne Hansen; Tveito, Siri; Høifødt, Hanne Kleppe; Bøhler, Per J.; Hole, Knut Håkon; Myklebost, Ola; Fodstad, Øystein; Smeland, Sigbjørn & Hovig, Eivind (2011). Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma. BMC Cancer.  ISSN 1471-2407.  11 . doi: 10.1186/1471-2407-11-455
  • Liu, Hao; Tekle, Christina; Chen, Yih Wen; Kristian, Alexandr; Zhao, Yuhua; Zhou, Ming; Liu, Zixing; Ding, Yan; Wang, Bin; Mælandsmo, Gunhild; Nesland, Jahn M; Fodstad, Øystein & Tan, Ming (2011). B7-H3 Silencing Increases Paclitaxel Sensitivity by Abrogating Jak2/Stat3 Phosphorylation. Molecular Cancer Therapeutics.  ISSN 1535-7163.  10(6), s 960- 971 . doi: 10.1158/1535-7163.MCT-11-0072
  • Risberg, Karianne; Fodstad, Øystein & Andersson, Yvonne (2011). Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in Melanoma. PLoS ONE.  ISSN 1932-6203.  6(9) . doi: 10.1371/journal.pone.0024012
  • Risberg, Karianne; Guldvik, Ingrid Jenny; Palchaudhuri, Rahul; Xi, Yaguang; Ju, Jingfang; Fodstad, Øystein; Hergenrother, Paul J. & Andersson, Yvonne (2011). Triphenylmethyl Derivatives Enhances the Anticancer Effect of Immunotoxins. Journal of immunotherapy (1997).  ISSN 1524-9557.  34(5), s 438- 447 . doi: 10.1097/CJI.0b013e31821e00ae
  • Sælen, Marie Grøn; Flatmark, Kjersti; Folkvord, Sigurd; de Wijn, Rik; Rasmussen, Heidi; Fodstad, Øystein & Ree, Anne Hansen (2011). Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination. Angiogenesis.  ISSN 0969-6970.  14(4), s 481- 489 . doi: 10.1007/s10456-011-9231-3
  • Tveito, Siri; Andersen, Kristin; Kåresen, Rolf & Fodstad, Øystein (2011). Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles. Breast Cancer Research.  ISSN 1465-542X.  13(4) . doi: 10.1186/bcr2922
  • Wang, Bin; Howel, Paul; Bruheim, Skjalg; Ju, Jingfang; Owen, Laurie B.; Fodstad, Øystein & Xi, Yaguang (2011). Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array. PLoS ONE.  ISSN 1932-6203.  6(2) . doi: 10.1371/journal.pone.0017167
  • Zhao, Yuhua; Liu, Hao; Liu, Zixing; Ding, Yan; Ledoux, Susan P.; Wilson, Glenn L.; Voellmy, Richard; Lin, Yifeng; Lin, Wensheng; Nahta, Rita; Liu, Bolin; Fodstad, Øystein; Chen, Jieqing; Wu, Yun; Price, Janet E. & Tan, Ming (2011). Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism. Cancer Research.  ISSN 0008-5472.  71(13), s 4585- 4597 . doi: 10.1158/0008-5472.CAN-11-0127
  • Zhao, Yuhua; Liu, Hao; Riker, Adam I; Fodstad, Øystein; Ledoux, Susan P.; Wilson, Glenn L. & Tan, Ming (2011). Emerging Metabolic Targets in Cancer Therapy. Frontiers in Bioscience.  ISSN 1093-9946.  16, s 1844- 1860 . doi: 10.2741/3826
  • Briggs, Jon; Haugen, Mads Haugland; Johansen, Harald Thidemann; Riker, Adam I; Abrahamson, Magnus; Fodstad, Øystein; Mælandsmo, Gunhild M & Solberg, Rigmor (2010). Cystatin E/M suppresses legumain activity and invasion of human melanoma. BMC Cancer.  ISSN 1471-2407.  10(1), s 17 . doi: 10.1186/1471-2407-10-17
  • Mercapide, Javier; Rappa, Germana; Anzanello, Fabio; King, Judy A; Fodstad, Øystein & Lorico, Aurelio (2010). Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma. International Journal of Cancer.  ISSN 0020-7136.  126(5), s 1206- 1215 . doi: 10.1002/ijc.24809
  • Metge, Brandon J.; Liu, Suhu; Riker, Adam I; Fodstad, Øystein; Samant, Rajeev S. & Shevde, Lalita A. (2010). Elevated Osteopontin Levels in Metastatic Melanoma Correlate with Epigenetic Silencing of Breast Cancer Metastasis Suppressor 1. Oncology.  ISSN 0030-2414.  78(1), s 75- 86 . doi: 10.1159/000292363
  • Ren, Suping; Liu, Suhu; Howell, Paul; Zhang, Guangyu; Pannell, Lewis; Samant, Rajeev S.; Shevde-Samant, Lalita; Tucker, J. Allan; Fodstad, Øystein & Riker, Adam I (2010). Functional characterization of the progestagen-associated endometrial protein gene in human melanoma. Journal of Cellular and Molecular Medicine (Print).  ISSN 1582-1838.  14(6B), s 1432- 1442 . doi: 10.1111/j.1582-4934.2009.00922.x
  • Risberg, Karianne; Fodstad, Øystein & Andersson, Yvonne (2010). Anti-Melanoma Activity of the 9.2.27PE Immunotoxin in Dacarbazine Resistant Cells. Journal of immunotherapy (1997).  ISSN 1524-9557.  33(3), s 272- 278 . doi: 10.1097/CJI.0b013e3181c54991
  • Schee, Kristina; Fodstad, Øystein & Flatmark, Kjersti (2010). MicroRNAs as Biomarkers in Colorectal Cancer. American Journal of Pathology.  ISSN 0002-9440.  177(4), s 1592- 1599 . doi: 10.2353/ajpath.2010.100024
  • Wiiger, Merete Thune; Gehrken, Hege Brandt; Fodstad, Øystein; Mælandsmo, Gunhild M & Andersson, Yvonne (2010). A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth. Cancer Immunology and Immunotherapy.  ISSN 0340-7004.  59(11), s 1665- 1674 . doi: 10.1007/s00262-010-0892-3
  • Zhou, Ming; Liu, Zixing; Zhao, Yuhua; Ding, Yan; Liu, Hao; Xi, Yaguang; Xiong, Wei; Li, Guiyuan; Lu, Jianrong; Fodstad, Øystein; Riker, Adam I & Tan, Ming (2010). MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression. Journal of Biological Chemistry.  ISSN 0021-9258.  285(28), s 21496- 21507 . doi: 10.1074/jbc.M109.083337
  • Zhou, Ming; Zhao, Yuhua; Ding, Yan; Liu, Hao; Liu, Zixing; Fodstad, Øystein; Riker, Adam I; Kamarajugadda, Sushama; Lu, Jianrong; Owen, Laurie B.; Ledoux, Susan P. & Tan, Ming (2010). Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol. Molecular Cancer.  ISSN 1476-4598.  9 . doi: 10.1186/1476-4598-9-33
  • Andersson, Y; Engebråten, Olav & Fodstad, Øystein (2009). Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo. British Journal of Cancer.  ISSN 0007-0920.  101(8), s 1307- 1315 . doi: 10.1038/sj.bjc.6605312
  • Bergamaschi, Anna; Hjortland, Geir Olav; Triulzi, T; Sørlie, Therese; Johnsen, Hilde; Ree, Anne Hansen; Russnes, Hege G; Tronnes, Sigurd; Mælandsmo, Gunhild M; Fodstad, Øystein; Børresen-Dale, Anne-Lise & Engebråten, Olav (2009). Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models. Molecular Oncology.  ISSN 1574-7891.  3(5-6), s 469- 482 . doi: 10.1016/j.molonc.2009.07.003
  • Bratland, Åse; Boender, PJ; Høifødt, Hanne Kleppe; Østensen, Ingrid H.G; Ruijtenbeek, R; Wang, MY; Berg, Jens Petter; Lilleby, Wolfgang; Fodstad, Øystein & Ree, Anne Hansen (2009). Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling. Clinical and Experimental Metastasis.  ISSN 0262-0898.  26(5), s 485- 496 . doi: 10.1007/s10585-009-9248-9
  • Bruheim, Skjalg; Xi, YG; Ju, JF & Fodstad, Øystein (2009). Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide. Clinical Cancer Research.  ISSN 1078-0432.  15(23), s 7161- 7169 . doi: 10.1158/1078-0432.CCR-08-2816
  • Chowdhury, Uttio Roy; Samant, Rajeev S.; Fodstad, Øystein & Shevde, Lalita A. (2009). Emerging role of nuclear protein 1 (NUPR1) in cancer biology. Cancer Metastasis Review.  ISSN 0167-7659.  28(1-2), s 225- 232 . doi: 10.1007/s10555-009-9183-x
  • Eide, Nils; Faye, Ragnar Solberg; Høifødt, Hanne Kleppe; Øvergaard, Ralf Gunnar; Jebsen, Peter Wilhelm; Kvalheim, Gunnar & Fodstad, Øystein (2009). Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients. Acta Ophthalmologica.  ISSN 1755-375X.  87(8), s 830- 836 . doi: 10.1111/j.1755-3768.2008.01378.x
  • Engebråten, Olav; Trikha, M; Juell, S; Garman-Vik, S & Fodstad, Øystein (2009). Inhibition of In Vivo Tumour Growth by the Blocking of Host alpha(v)beta(3) and alpha IIb beta(3) Integrins. Anticancer Research.  ISSN 0250-7005.  29(1), s 131- 137
  • Liu, Suhu; Howell, Paul; Ren, Suping; Fodstad, Øystein & Riker, Adam I (2009). The 14-3-3 sigma gene promoter is methylated in both human melanocytes and melanoma. BMC Cancer.  ISSN 1471-2407.  9 . doi: 10.1186/1471-2407-9-162
  • Liu, Suhu; Howell, Paul; Ren, Suping; Fodstad, Øystein; Zhang, GY; Samant, R; Shevde, L; Xi, YG; Pannell, LK & Riker, Adam I (2009). Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma. Clinical and Experimental Metastasis.  ISSN 0262-0898.  26(7), s 739- 749 . doi: 10.1007/s10585-009-9273-8
  • Risberg, Karianne; Fodstad, Øystein & Andersson, Yvonne (2009). The melanoma specific 9.2.27PE immunotoxin efficiently kills melanoma cells in vitro. International Journal of Cancer.  ISSN 0020-7136.  125(1), s 23- 33 . doi: 10.1002/ijc.24317
  • Song, B; Wang, Y; Xi, Y; Kudo, K; Bruheim, Skjalg; Botchkina, GI; Gavin, E; Wan, Y; Formentini, A; Kornmann, M; Fodstad, Øystein & Ju, J (2009). Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene.  ISSN 0950-9232.  28(46), s 4065- 4074 . doi: 10.1038/onc.2009.274
  • Zhao, YH; Zhou, M; Liu, H; Ding, Y; Khong, HT; Yu, D.; Fodstad, Øystein & Tan, M (2009). Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. Oncogene.  ISSN 0950-9232.  28(42), s 3689- 3701 . doi: 10.1038/onc.2009.229
  • Brunsvig, Paal Fredrik; Flatmark, Kjersti; Aamdal, Steinar; Høifødt, Hanne Kleppe; Le, H; Jakobsen, E; Sandstad, Berit & Fodstad, Øystein (2008). Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients. Lung Cancer.  ISSN 0169-5002.  61(2), s 170- 176 . doi: 10.1016/j.lungcan.2007.12.018
  • Chen, YW; Tekle, Christina & Fodstad, Øystein (2008). The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion. Current Cancer Drug Targets.  ISSN 1568-0096.  8, s 404- 413 . doi: http://docstore.ingenta.com/cgi-bin/ds_deliver/1/u/d/ISIS/48144909.1/ben/ccdt/2008/00000008/00000005/art00007/37A0707C8D6EC6141231759169F36DD75A11ECE012.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
  • Clark, DW; Mitra, A; Fillmore, RA; Jiang, WG; Samant, RS; Fodstad, Øystein & Shevde, LA (2008). NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress. Current Cancer Drug Targets.  ISSN 1568-0096.  8, s 421- 430
  • Bauer, NN; Chen, YW; Samant, RS; Shevde, LA & Fodstad, Øystein (2007). Rac1 activity regulates proliferation of aggressive metastatic melanoma. Experimental Cell Research.  ISSN 0014-4827.  313, s 3832- 3839
  • Flatmark, Kjersti; Reed, W; Halvorsen, T; Sorensen, O; Wiig, JN; Larsen, SG; Fodstad, Øystein & Giercksky, Karl-Erik (2007). Pseudomyxoma peritonei - two novel orthotopic mouse models portray the PMCA-I histopathologic subtype. BMC Cancer.  ISSN 1471-2407.  7, s 116 . doi: 10.1186/1471-2407-7-116
  • Lillehammer, T; Engesaeter, BO; Prasmickaite, L; Maelandsmo, GM; Fodstad, Øystein & Engebråten, Olav (2007). Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines. Journal of Gene Medicine.  ISSN 1099-498X.  9, s 440- 451 . doi: 10.1002/jgm.1036
  • Tveito, S; Maelandsmo, GM; Hoifodt, HK; Rasmussen, H & Fodstad, Øystein (2007). Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value. Clinical and Experimental Metastasis.  ISSN 0262-0898.  24, s 317- 327 . doi: 10.1007/s10585-006-9052-8
  • Flatmark, Kjersti; Nome, Ragnhild; Folkvord, Sigurd; Bratland, Åse; Rasmussen, Heidi; Ellefsen, M*; Ellefsen, Mali S; Fodstad, Øystein & Ree, Anne Hansen (2006). Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition. Radiation Oncology.  ISSN 1748-717X.  1, s 25
  • Bjørnland, Kristin; Flatmark, Kjersti; Pettersen, Solveig; Aasen, Ansgar Oddne; Fodstad, Øystein & Mælandsmo, Gunhild M (2005). Matrix metalloproteinases participate in osteosarcoma invasion. Journal of Surgical Research.  ISSN 0022-4804.  127(2), s 151- 156
  • Bruland, Øyvind; Høifødt, Hanne Kleppe; Sæter, Gunnar; Smeland, Sigbjørn & Fodstad, Øystein (2005). Hematogenous micrometastases in osteosarcoma patients. Clinical Cancer Research.  ISSN 1078-0432.  11, s 4666- 4673
  • Lorico, Aurelio; Bratbak, daniel; Meyer, Johann; Kunke, David; Krauss, Stefan; Plott, Walter; Solodushko, Victor; Baum, Christopher; Fodstad, Øystein & Rappa, Germana (2005). Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells. Human Gene Therapy.  ISSN 1043-0342.  16, s 711- 724
  • Nome, Ragnhild; Bratland, Åse; Harman, Gunhild; Fodstad, Øystein & Ree, Anne Hansen (2005). Cell cycle checkpoint signaling involved in histone deacetylase inhibition and radiation-induced cell death. Molecular Cancer Therapeutics.  ISSN 1535-7163.  4(8), s 1231- 1238 . doi: 10.1158/1535-7163.MCT-04-0304
  • Andersson, Yvonne; Juell, Siri & Fodstad, Øystein (2004). Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-pseudomonas exotoxin a immunotoxin. International Journal of Cancer.  ISSN 0020-7136.  112, s 475- 483 . doi: 10.1002/ijc.20371
  • Bergman, A.M; Kuiper, C.M; Noordhuis, P; Smid, K; Comijn, E.M; Myhren, F.; Sandvold, M. Liland; Hendriks, H.R; Fodstad, Øystein & Peters, G.J (2004). Antiproliferative activity and mechanism of action of fatty acid delivatives of gemcitabine in leukemia and solid tumor cell lines and in human xenografts. Nucleosides, Nucleotides & Nucleic Acids.  ISSN 1525-7770.  23(8-9), s 1329- 1333
  • Bruheim, S; Bruland, Øyvind; Breistøl, Knut; Mælandsmo, Gunhild M & Fodstad, Øystein (2004). Human osteosarcoma xenografts and their sensitivity to chemotherapy. Pathology and Oncology Research.  ISSN 1219-4956.  10(3), s 133- 141
  • Faye, Ragnar Solberg; Aamdal, Steinar; Høifødt, Hanne Kleppe; Jacobsen, E; Holstad, L; Skovlund, Eva & Fodstad, Øystein (2004). Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients. Clinical Cancer Research.  ISSN 1078-0432.  10, s 4134- 4139
  • Flatmark, Kjersti; Mælandsmo, Gunhild M; Martinsen, Marita; Rasmussen, Heidi & Fodstad, Øystein (2004). Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. European Journal of Cancer.  ISSN 0959-8049.  40, s 1593- 1598 . doi: 10.1016/j.ejca.2004.02.023
  • Flatmark, Kjersti; Mælandsmo, Gunhild M; Mikalsen, Svein-Ole; Nustad, Kjell; Varaas, Tone; Rasmussen, Heidi; Meling, Gunn Iren; Fodstad, Øystein & Paus, Elisabeth (2004). Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum. Tumour Biology.  ISSN 1010-4283.  25(1-2), s 31- 40 . doi: 10.1159.000077721
  • Jiang, Wen G; Watkins, Gareth; Fodstad, Øystein; Douglas-Jones, Anthony; Mokbel, Kefah & Mansel, Robert E (2004). Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer. Endocrine-Related Cancer.  ISSN 1351-0088.  11, s 781- 791 . doi: 10.1677/erc.1.00825
  • King, Judy A; Ofori-Acquah, Solomon F; Stevens, Troy; Al-Mehdi, Abu-Bakr; Fodstad, Øystein & Jiang, Wen G (2004). Activated leukocyte cell adhesion moecule in breast cancer: prognostic indicator. Breast Cancer Research.  ISSN 1465-542X.  6, s R478- R487 . doi: 10.1186/bcr815
  • Pedersen, Kjetil Boye; Andersen, Kristin; Fodstad, Øystein & Mælandsmo, Gunhild M (2004). Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4. BMC Cancer.  ISSN 1471-2407.  4, s 52 . doi: 10.1186/1471-2407-4-52
  • Ree, Anne Hansen; Bratland, Åse; Nome, Ragnhild V; Stokke, Trond; Fodstad, Øystein & Andersson, Yvonne (2004). Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?. Radiotherapy and Oncology.  ISSN 0167-8140.  72, s 305- 310
  • Ree, Anne Hansen; Landsverk, Solberg & Fodstad, Øystein (2004). Ionizing radiation inhibits the PLK cell cycle gene in a G2 checkpoint-dependent manner. Anticancer Research.  ISSN 0250-7005.  24(2B), s 555- 562
  • Andersen, Kristin; Nesland, Jahn M; Holm, Ruth; Flørenes, Vivi Ann; Fodstad, Øystein & Mælandsmo, Gunhild M (2004). Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma. Modern Pathology.  ISSN 0893-3952.  17, s 990- 997
  • Hjortland, Geir Olav; Garman-Vik, Solveig Suzanne; Juell, Siri; Olsen, Øyvind Edon; Hirschberg, Henry; Fodstad, Øystein & Engebråten, Olav (2004). Immunotoxin treatment targeted to the high-molecular-weight melanoma-associated antigen prolonging the survival of immunodeficient rats with invasive intracranial human glioblastoma multiforme. Journal of Neurosurgery.  ISSN 0022-3085.  100, s 320- 327
  • Hjortland, Geir Olav; Lillehammer, Trine; Somme, Stig; Wang, Junbai; Halvorsen, Thomas; Juell, Siri; Hirschberg, Henry; Fodstad, Øystein & Engebråten, Olav (2004). Plasminogen activator inhibitor-1 increases the expression of VEGF in human glioma cells. Experimental Cell Research.  ISSN 0014-4827.  294, s 130- 139 . doi: 10.1016/j.yexcr.10.013

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  • Bruheim, Skjalg & Fodstad, Øystein (2010). Preclinical studies of human osteosarcoma -Therapy response and search for biomarkers.
  • Fodstad, Øystein; Tveito, Siri; Kåresen, Rolf & Sauer, Torill (2010). Metastasis - gene expression differences associated with site and treatment sensitivity. European Journal of Cancer.  ISSN 0959-8049.  8(5), s 156- 156
  • Prasmickaite, Lina; Skrbo, Nirma; Høifødt, Hanne Kleppe; Suo, Zhenhe; Engebråten, Olav; Gullestad, Hans petter; Aamdal, Steinar; Fodstad, Øystein & Mælandsmo, Gunhild M (2010). Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells. Pigment Cell & Melanoma Research.  ISSN 1755-1471.  23(3), s 449- 451 . doi: 10.1111/j.1755-148X.2010.00690.x
  • Risberg, Karianne; Andersson, Yvonne & Fodstad, Øystein (2010). Immunotoxins in targeted therapy of cancer – a study in malignant melanoma cells.
  • Wiiger, Merete Thune; Fodstad, Øystein & Andersson, Yvonne (2010). Characterization of novel recombinant human single chain cancer-specific antibodies. European Journal of Cancer.  ISSN 0959-8049.  8(5), s 56- 56
  • Bratland, Åse; Ree, Anne Hansen & Fodstad, Øystein (2009). Therapeutic targeting of molecular mechanisms involved in tumor progression and metastasis.
  • Briggs, Jon; Haugen, Mads Haugland; Johansen, Harald Thidemann; Riker, Adam I; Abrahamson, Magnus; Fodstad, Øystein; Mælandsmo, Gunhild Mari & Solberg, Rigmor (2009). Cystatin E/M suppresses legumain activity and invasion of human melanoma.
  • Bøe, Sigurd; Hovig, Eivind & Fodstad, Øystein (2009). Modulation of gene expression using natural and artificial nucleic acids combined with photochemical internalization technology.
  • Fodstad, Øystein; Tveito, Siri; Høifødt, Hanne Kleppe; Park, Daehoon; Sauer, Torill & Kåresen, Rolf (2009). Detection and characterization of tumour cells in sentinel lymph nodes and bone marrow of patients with breast cancer. European Journal of Cancer.  ISSN 0959-8049.  7(2), s 70- 71
  • Eide, Nils; Overgaard, R; Jebsen, P; Qvale, Geir Aksel; Faye, Ragnar Solberg; Hoifodt, HK; Kvalheim, Gunnar & Fodstad, Øystein (2008). Micrometastases in uveal melanoma, a comparison of the test results in bone marrow and clinical outcome. Acta Ophthalmologica.  ISSN 1755-375X.  86, s 40- 40
  • Liu, Fang; Hovig, Eivind; Jenssen, Tor-Kristian & Fodstad, Øystein (2007). Large-scale bioinfomatics studies of DNA denaturation and transcriptome profiling technologies.
  • Eide, Nils; Øvergaard, Ralf Gunnar; Jebsen, Peter; Qvale, Geir A; Faye, Ragnar Solberg; Høifødt, Hanne Kleppe; Kvalheim, Gunnar; Aamdal, Steinar & Fodstad, Øystein (2004). Evalution of 9.2.27 melanoma antibody in micro metastases in malignant uveal melanoma and a comparision of the test results in the eye tumour, the bone marrow and peripheral blood.

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Publisert 8. apr. 2015 14:55