Geir Christensen

Bilde av Geir Christensen
English version of this page
Telefon +47-90671853
Brukernavn
Besøksadresse Kirkeveien 166 Bygg 7 0450 OSLO
Postadresse Postboks 4956 Nydalen 0424 OSLO

Faglige interesser

Forskning på hjertesvikt

Undervisning

Leder for PhD School of Heart Failure
http://www.heartfailure.no/education/ 

Bakgrunn

Medisinsk embetseksamen (cand. med.) 1980     

Autorisasjon som lege 1982               

Medisinsk doktorgrad (dr. med.) ved Universitetet i Oslo 1993           

Mastergrad i helseadministrasjon, Senter for helseadministrasjon, Universitetet i Oslo 2004                                                  

Priser

Nasjonalforeningens hjertepris 2011

http://www.kongehuset.no/c26939/nyhet/vis.html?tid=89563 

Verv

Leder for Senter for hjertesviktforskning

http://www.heartfailure.no/ 

Samarbeid

Utstrakt nasjonalt og internasjonalt samarbeid innen hjerteforskning

 

Emneord: Hjertesvikt, Hjerte, Molekylær

Publikasjoner

  • Abraityte, Judita Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika; Christensen, Geir Arve; Aukrust, Pål; Yndestad, Arne; Fiane, Arnt E; Andreassen, Arne K.; Aakhus, Svend; Dahl, Christen Peder; Gullestad, Lars; Broch, Kaspar & Ueland, Thor (2017). Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-03625-9
  • Abraityte, Judita Aurelija; Vinge, Leif Erik; Askevold, Erik Tandberg; Lekva, Tove; Michelsen, Annika; Ranheim, Trine; Alfsnes, Katrine; Fiane, Arnt E; Aakhus, Svend; Lunde, Ida Gjervold; Dahl, Christen Peder; Aukrust, Pål; Christensen, Geir Arve; Gullestad, Lars; Yndestad, Arne & Ueland, Thor (2017). Wnt5a is elevated in heart failure and affects cardiac fibroblast function. Journal of Molecular Medicine.  ISSN 0946-2716.  95(7), s 767- 777 . doi: 10.1007/s00109-017-1529-1
  • Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil; Attramadal, Håvard; Finsen, Alexandra; Zhang, Lili; Ranheim, Trine; Alfsnes, Katrine; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation.  ISSN 0962-9351.  2017:9450439, s 1- 11 . doi: 10.1155/2017/9450439
  • Norum, Hilde Margrethe; Broch, Kaspar; Michelsen, Annika; Lunde, Ida Gjervold; Lekva, Tove; Abraityte, Judita Aurelija; Dahl, Christen Peder; Fiane, Arnt E; Andreassen, Arne K.; Christensen, Geir Arve; Aakhus, Svend; Aukrust, Pål; Gullestad, Lars & Ueland, Thor (2017). The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy. Journal of Cardiovascular Translational Research.  ISSN 1937-5387.  s 1- 10 . doi: 10.1007/s12265-017-9748-y
  • Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar & Finsen, Alexandra (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports.  ISSN 2211-1247.  18, s 82- 92 . doi: 10.1016/j.celrep.2016.12.009
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune Forstrøm; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Sjaastad, Ivar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2017). Glycosyalted chromogranin A in heart faiure. Implications for processing and cardiomyocyte calcium homeostasis. Circulation: Heart Failure.  ISSN 1941-3289.  10:e003675(2) . doi: 10.1161/CIRCHEARTFAILURE.116.003675
  • Ottesen, Anett Hellebø; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2017). Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure. Current Heart Failure Reports.  ISSN 1546-9530.  s 1- 11 . doi: 10.1007/s11897-017-0360-x
  • Pervez, Mohammad Osman; Lyngbakken, Magnus Nakrem; Myhre, Peder Langeland; Brynildsen, Jon; Langsjøen, Eva Camilla; Høiseth, Arne Didrik; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2017). Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. Clinical Biochemistry.  ISSN 0009-9120.  50(7-8), s 394- 400 . doi: 10.1016/j.clinbiochem.2016.12.010
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Sejersted, Ole M; Christensen, Geir Arve; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research.  ISSN 0008-6363. . doi: 10.1093/cw111
  • Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne; Christensen, Geir Arve; Søyseth, Vidar; Omland, Torbjørn & Røsjø, Helge (2016). The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: Data from the Akershus cardiac examination (ACE) 2 study. Biomarkers.  ISSN 1354-750X.  21(2), s 173- 179 . doi: 10.3109/1354750X.2015.1126645
  • Lunde, Ida Gjervold; Herum, Kate Louise Møller; Carlson, Cathrine Rein & Christensen, Geir Arve (2016). Syndecans in heart fibrosis. Cell and Tissue Research.  ISSN 0302-766X.  365(3), s 539- 552 . doi: 10.1007/s00441-016-2454-2
  • Melleby, Arne Olav; Strand, Mari Elen; Romaine, Andreas; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Arnt E; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparan sulfate proteoglycan glypican-6 is upregulated in the failing heart, and regulates cardiomyocyte growth through ERK1/2 Signaling. PLoS ONE.  ISSN 1932-6203.  11(10) . doi: 10.1371/journal.pone.0165079
  • Myhre, Peder Langeland; Ottesen, Anett Hellebø; Okkonen, Marjatta; Linko, Rita; Stridsberg, Mats; Nygård, Ståle; Christensen, Geir Arve; Pettilä, Ville; Omland, Torbjørn & Røsjø, Helge (2016). Prognostic value of secretoneurin in patients with acute respiratory failure:Data from the FINNALI study. Clinical Chemistry.  ISSN 0009-9147.  62(10), s 1380- 1389 . doi: 10.1373/clinchem.2016.258764
  • Røsjø, Helge; Stridsberg, Mats; Ottesen, Anett Hellebø; Nygård, Ståle; Christensen, Geir Arve; Pettilä, Ville; Linko, Rita; Karlsson, Sari; Varpula, Tero; Ruokonen, Esko & Omland, Torbjørn (2016). Prognostic Value of Secretoneurin in Critically Ill Patients with Infections. Critical Care Medicine.  ISSN 0090-3493.  44(10), s 1882- 1890 . doi: 10.1097/CCM.0000000000001832
  • Winther, Jacob Andreas; Brynildsen, Jon; Høiseth, Arne Didrik; Følling, Ivar; Brekke, Pål Haugar; Christensen, Geir Arve; Hagve, Tor-Arne; Verbalis, Joseph G.; Omland, Torbjørn & Røsjø, Helge (2016). Prevalence and prognostic significance of hyponatremia in patients with acute exacerbation of chronic obstructive pulmonary disease: Data from the akershus cardiac examination (ACE) 2 study. PLoS ONE.  ISSN 1932-6203.  11:e0161232(8) . doi: 10.1371/journal.pone.0161232 Fulltekst i vitenarkiv.
  • Brynildsen, Jon; Høiseth, Arne Didrik; Nygård, Ståle; Hagve, Tor-Arne; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2015). Diagnostisk treffsikkerhet for hjertesvikt – data fra Akershus hjerteundersøkelse 2. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  135(19), s 1738- 1744 . doi: 10.4045/tidsskr.14.1174
  • Dhondup, Yangchen; Sjaastad, Ivar; Scott, Helge; Sandanger, Øystein; Zhang, Lili; Haugstad, Solveig Bjærum; Aronsen, Jan Magnus; Ranheim, Trine; Holmen, Sigve; Alfsnes, Katrine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Gullestad, Lars; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2015). Sustained toll-like receptor 9 activation promotes systemic and cardiac inflammation, and aggravates diastolic heart failure in SERCA2a KO Mice. PLoS ONE.  ISSN 1932-6203.  10:e0139715(10) . doi: 10.1371/journal.pone.0139715 Fulltekst i vitenarkiv.
  • Einvik, Gunnar; Dammen, Toril; Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2015). Psychological distress and mortality in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. General Hospital Psychiatry.  ISSN 0163-8343.  37(6), s 548- 553 . doi: 10.1016/j.genhosppsych.2015.07.007
  • Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309(4), s L378- L387 . doi: 10.1152/ajplung.00342.2014
  • Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasone adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309, s L378- L387 . doi: 10.1152/ajplung.00342.2014
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Boye, Sigurd; Unger, Andreas; Brorson, Sverre Henning; Sjaastad, Ivar; Tønnessen, Theis; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2015). Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart. Cardiovascular Research.  ISSN 0008-6363.  106, s 217- 226 . doi: 10.1093/cvr/cvv002
  • Hillestad, Vigdis; Espe, Emil Knut Stenersen; Fadila, Cero; Larsen, Karl-Otto; Sjaastad, Ivar; Nygård, Ståle; Skjønsberg, Ole Henning & Christensen, Geir Arve (2015). IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice. Acta Physiologica.  ISSN 1748-1708.  213(2), s 492- 504 . doi: 10.1111/apha.12376
  • Kho, Changwon; Lee, Ahyoung; Jeong, Dongtak; Oh, Jae Gyun; Gorski, Przemek A.; Fish, Kenneth; Sanchez, Roberto; DeVita, Robert J; Christensen, Geir Arve; Dahl, Russell & Hajjar, Roger J. (2015). Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nature Communications.  ISSN 2041-1723.  6:7229 . doi: 10.1038/ncomms8229
  • Majak, Piotr; Lunde, Ida Gjervold; Hasic, Almira; Husebye, Trygve Guttorm; Christensen, Geir Arve; Tønnessen, Theis & BJØRNSTAD, JOHANNES (2015). Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling. Journal of Cardiovascular Surgery.  ISSN 0021-9509.  56(3), s 483- 492
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. Journal of the American College of Cardiology.  ISSN 0735-1097.  65(4), s 339- 351 . doi: 10.1016/j.jacc.2014.10.065
  • Røsjø, Helge; Dahl, Mai Britt; Pedersen, Marit Holmefjord; Røysland, Ragnhild; Brynildsen, Jon; Cataliotti, Alessandro; Christensen, Geir Arve; Høiseth, Arne Didrik; Hagve, Tor-Arne & Omland, Torbjørn (2015). Influence of glycosylation on diagnostic and prognostic accuracy of N-terminal pro-b-type natriuretic peptide in acute dyspnea: Data from the Akershus cardiac examination 2 study. Clinical Chemistry.  ISSN 0009-9147.  61(8), s 1087- 1097 . doi: 10.1373/clinchem.2015.239673
  • Skrbic, Biljana; Engebretsen, Kristin V Thunheim; Strand, Mari Elen; Lunde, Ida Gjervold; Herum, Kate Louise Møller; Marstein, Henriette; Sjaastad, Ivar; Lunde, Per Kristian; Carlson, Cathrine Rein; Christensen, Geir Arve; BJØRNSTAD, JOHANNES & Tønnessen, Theis (2015). Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice. Cardiovascular Research.  ISSN 0008-6363.  106(1), s 32- 42 . doi: 10.1093/cvr/cvv041
  • Strand, Mari Elen; Aronsen, Jan Magnus; Braathen, Bjørn; Sjaastad, Ivar; Kvaløy, Heidi; Tønnessen, Theis; Christensen, Geir Arve & Lunde, Ida Gjervold (2015). Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  88, s 133- 144 . doi: 10.1016/j.yjmcc.2015.10.003
  • Askevold, Erik Tandberg; Aukrust, Pål; Nymo, Ståle Haugset; Lunde, Ida Gjervold; Kaasbøll, Ole Jørgen; Aakhus, Svend; Florholmen, Geir; Ohm, Ingrid Kristine; Strand, Mari; Attramadal, Håvard; Fiane, Arnt E; Dahl, Christen Peder; Finsen, Alexandra; Vinge, Leif Erik; Christensen, Geir Arve; Yndestad, Arne; Gullestad, Lars; Latini, R; Masson, S; Tavazzi, Luigi & Ueland, Thor (2014). The cardiokine secreted Frizzled related protein 3, a modulator of Wnt-signalling, in clinical and experimental heart failure. Journal of Internal Medicine.  ISSN 0954-6820.  275(6), s 621- 630 . doi: 10.1111/joim.12175
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  306(7), s H1018- H1024 . doi: 10.1152/ajpheart.00741.2013
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135. . doi: 10.1152/ajpheart.00741.2013 Fulltekst i vitenarkiv.
  • Engebretsen, Kristin V Thunheim; Skårdal, Kristine; Bjørnstad, Sigrid; Marstein, Henriette; Skrbic, Biljana; Sjaastad, Ivar; Christensen, Geir Arve; BJØRNSTAD, JOHANNES & Tønnessen, Theis (2014). Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  76, s 148- 157 . doi: 10.1016/j.yjmcc.2014.08.008
  • Finsen, Alexandra; Ueland, Thor; Sjaastad, Ivar; Ranheim, Trine; Ahmed, Muhammad Shakil; Dahl, Christen Peder; Askevold, Erik Tandberg; Aakhus, Svend; Husberg, Cathrine; Fiane, Arnt E; Lipp, Martin; Gullestad, Lars; Christensen, Geir Arve; Aukrust, Pål & Yndestad, Arne (2014). The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling. PLoS ONE.  ISSN 1932-6203.  9, s e112172 . doi: 10.1371/journal.pone.0112172
  • Misceo, Doriana; Holmgren, Asbjørn; Louch, William Edward; Holme, Pål Andre; Mizobuchi, Masahiro; Morales, Raul J.; De Paula, André Maues; Stray-Pedersen, Asbjørg; Lyle, Robert; Dalhus, Bjørn; Christensen, Geir Arve; Stormorken, Helge; Tjønnfjord, Geir Erland & Frengen, Eirik (2014). A Dominant STIM1 Mutation Causes Stormorken Syndrome. Human Mutation.  ISSN 1059-7794.  35(5), s 556- 564 . doi: 10.1002/humu.22544
  • Nygård, Ståle; Reitan, Trond; Clancy, Trevor; Nygaard, Vegard; BJØRNSTAD, JOHANNES; Skrbic, Biljana; Tønnessen, Theis; Christensen, Geir Arve & Hovig, Johannes Eivind (2014). Identifying pathogenic processes by integrating microarray data with prior knowledge. BMC Bioinformatics.  ISSN 1471-2105.  15(1) . doi: 10.1186/1471-2105-15-115
  • Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2016). BIN1 triggers t-tubule development in cardiomyocytes.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Benson, Craig; DePalma, Steve; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2016). Study of a mouse with proximal titin A-band truncation reveals disease mechanisms and modifiers of titin dilated cardiomyopathy.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Gorham, Joshua; DePalma, Steve; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2016). Titin A-band truncation mutation in mice causes stress-induced dilated cardiomyopathy.
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan - 2.
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan-2.
  • Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Andrew; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). Glypican-6 is upregulated in heart failure and mediates cardiomyocyte growth through ERK1/2 signaling.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
  • Romaine, Andreas; Sørensen, Ida Wiig; Melleby, Arne Olav; Zeltz, Cedric; Zhang, Lili; Bendiksen, Bård Andre; Lu, Neha; Herum, Kate Louise Møller; Danielsen, D.; Sjaastad, Ivar; Gullberg, Donald & Christensen, Geir Arve (2016). Overexpression of integrin a11 induces cardiac hypertrophy and fibrosis.
  • Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five; Aakhus, Svend; Lunde, Ida Gjervold; Almaas, Vibeke; Gullestad, Lars; Sjaastad, Ivar; Tønnessen, Theis; Sejersted, Ole M; Norseng, Per Andreas; Christensen, Geir Arve & Louch, William Edward (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Høst, Vibeke; Aronsen, Jan Magnus; Liland, Kristian Hovde; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2016). Syndecan-4 is important for normal skeletal muscle fibre development.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Andenæs, Kine; Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Strand, Mari Elen; Marstein, Henriette; Dahl, Christen Peder; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2015). The extracellular matrix proteoglycan fibromodulin is up-regulated in experimental and clinical heart failure, and might be involved in regulation of myocardial fibrosis by interacting with TGF-B.
  • Carlson, Cathrine Rein; Nygård, Ståle; Sirnes, Solveig; Jarstadmarken, Hilde; Martinsen, Marita; Lunde, Marianne; Tutturen, Astrid Elisabeth Voorham; De Souza, Gustavo Antonio & Christensen, Geir Arve (2015). A protein-protein interaction (PPI) map of cardiac syndecan-4.
  • Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Løberg, Else Marit; Christensen, Geir Arve & Skjønsberg, Ole Henning (2015). The inflammasome adaptor ASC mediates pulmonary artery remodelling.
  • Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla; Yndestad, Arne; Aukrust, Pål; Løberg, Else Marit; Christensen, Geir Arve & Skjønsberg, Ole Henning (2015). Hypoxic pulmonary hypertension; a role for the inflammasome.
  • Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five; Almaas, Victor; Gullestad, Lars; Christensen, Geir Arve; Aakhus, Svend; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Christensen, Geir Arve; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2015). Ventricular wall stress predicts disruption of cardiomyocyte t-tubule structure and Ca2+ homeostasis across the infarcted heart. Biophysical Journal.  ISSN 0006-3495.  108, s 106a
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (BIN1) initiates t-tubule Growth during Cardiac Development and disease. Biophysical Journal.  ISSN 0006-3495.  108, s 130a- 130a
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sjaastad, Ivar; Wasserstrom, Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang A.; Gorham, joshua; Conner, David; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Proximal titin A-band truncation causes dilated cardiomyopathy in response to increased afterload in mice.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang E.; Gorham, Joshua; Conner, David; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Gorham, joshua; Conner, David; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2015). 7th Joint Scandinavian Conference in Cardiothoracic Surgery.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Jianming, Jiang; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Gorham, Joshua; DePalma, Steve; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
  • Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Arnt E; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2015). Glypican-6 is increased in experimental and clinical heart failure and might play a role in cardiac fibrosis through BMP4 signalling.
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V.; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Edwards, Andrew; Landsverk, Ole J. B.; Johansen, Rune Forstrøm; Moe, Morten Kaare; Bjørås, Magnar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin,a novel endogenous CaMKII inhibitor, augments cardiomyocyte Calcium handling and inhibits arrhythmogenic Calcium release. Biophysical Journal.  ISSN 0006-3495.  108, s 340a- 340a
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune F.; Jarstadmarken, Hilde; Bjørås, Magnar; Sjaastad, Ivar; Høiseth, Arne Didrik; Brynildsen, Jon; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Enhanced myocardial chromogranin A glycosylation in acute heart failure: reduced processing and potential impact on cardiomyocyte calcium homeostasis.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Johansen, Rune F.; Stridsberg, Mats; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Chromogranin A is a potent prognostic biomarker in acute heart failure, and its fragment catestatin regulates cardiomyocyte calcium homeostasis by CaMKII inhibition.
  • Ottesen, Anett Hellebø; Laver, Derek; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin a novel endogenous CaMKIIð inhibitor, inhibits Ca2+ dependent arrhythmogenesis.
  • Romaine, Andreas; Herum, Kate Louise Møller; Sørensen, Ida Wiig; Hasic, Almira; Sjaastad, Ivar; Gullberg, Donald & Christensen, Geir Arve (2015). Syndecan-4 regulates profibrotic a11B1 integrin expression in the pressure-overloaded heart.
  • Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Regulation of cardiomyocyte t-tubule organization and density by ventricular wall stress. Biophysical Journal.  ISSN 0006-3495.  108, s 443a- 443a
  • Rønning, Sissel Beate; Carlson, C. R.; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve; Hollung, Kristin & Pedersen, Mona Elisabeth (2015). Syndecan-4 in skeletal muscle development and regeneration.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Hollung, Kristin; Pedersen, Mona Elisabeth; Stang, Espen; Kolset, Svein Olav & Christensen, Geir Arve (2015). Syndecan-4 in skeletal muscle development and regeneration.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve; Hollung, Kristin & Pedersen, Mona Elisabeth (2015). Syndecan-4 is important for skeletal muscle development.
  • Røsjø, Helge; Masson, Serge; Caironi, Pietro; Stridsberg, Mats; Fanizza, Caterina; Christensen, Geir Arve; Moise, Gabriella; Urbano, Maria Cristina; Gattinoni, Luciano; Latini, Roberto & Omland, Torbjørn (2015). The novel cardiac biomarker secretoneurin provides independent prognostic information in severe sepsis and septic shock: data from the ALBIOS study. Circulation.  ISSN 0009-7322.  132(A14598)
  • Sandbu, Ragnhild Askeland; Dahl, Mai Britt; Ottesen, Anett Hellebø; Jørgensen, M; Stridsberg, Mats; Sjaastad, Ivar; Høiseth, Arne Didrik; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Chromogranin A is glycosylated in acute heart failure and this is associated with reduced processing to the functional peptide catestatin and increased mortality.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Braathen, Bjørn; Sjaastad, Ivar; Kvaløy, Heidi; Tønnessen, Theis; Christensen, Geir Arve & Lunde, Ida Gjervold (2015). Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice.
  • Udjus, Camilla; Cero, Fadila; Christensen, Geir Arve; Skjønsberg, Ole Henning & Larsen, Karl-Otto (2015). The role of caspase-1 in pulmonary hypertension.
  • Ytrehus, Kirsti; Larsen, Terje; Christensen, Geir Arve; Stensløkken, Kåre-Olav & Levy, Finn Olav (2015). In memory of Guro Valen (1960-2014). Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  79, s 254- 255 . doi: 10.1016/j.yjmcc.2014.11.026
  • Bandlien, Caroline; Engebretsen, Kristin V Thunheim; Skrbic, Biljana; Lunde, Ida Gjervold; Sjaastad, Ivar; Christensen, Geir Arve & Tønnessen, Theis (2014). Lack of lumican in cardiac pressure overload attenuates development of cardiac fibrosis leading to premature left ventricle dilatation.
  • Bandlien, Caroline; Engebretsen, Kristin V Thunheim; Skrbic, Biljana; Marstein, Henriette; Lunde, Ida Gjervold; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2014). Lack of lumican in cardiac pressure overload attenuates development of cardiac fibrosis leading to premature left ventricle dilatation.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Boye, Sigurd; Unger, Andreas; Linke, Wolfgang A.; Brorson, Sverre Henning; Sjaastad, Ivar; Tønnessen, Theis; Gomez, Maria F. & Christensen, Geir Arve (2014). Syndecan-4 is a key determinant of collagen cross-linking and myocardial stiffness in the pressure-overloaded heart.
  • Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Tønnessen, Theis; Louch, William Edward; Hasic, Almira; Sjaastad, Ivar; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2014). Syndecan-4 promotes myocardial stiffness by regulating collagen expression and cross-linking in response to pressure overload. The FASEB Journal.  ISSN 0892-6638.  28
  • Kolstad, Terje R Selnes; Stokke, Mathis Korseberg; Stang, Espen; Brorson, Sverre Henning; Christensen, Geir Arve; Louch, William Edward & Sejersted, Ole M (2014). SERCA localized near the dyad regulates calcium release in cardiac myocytes.
  • Lipsett, David Bruce; Frisk, Michael; Hodne, Kjetil; Singh, Neha; Nygård, Ståle; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, Andrew J.; Christensen, Geir Arve & Louch, William Edward (2014). B1N1 controls longitudinal T-tubule growth in cardiomyocytes during development and disease.
  • Lipsett, David Bruce; Singh, Neha; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2014). Bridging integrator 1 (BIN1)-induced t-tubule formation in cardiomyocytes. Biophysical Journal.  ISSN 0006-3495.  106(2), s 772a
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Linke, Wolfgang A.; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2014). A deletion in the N2A region of titin carried by muscular dystrophy with myositis (mdm) mice severely afftected skeletal muscle, but not the heart.
  • Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Linke, Wolfgang; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2014). A deletion in the N2A region of titin carried by muscular dystrophy with myositis (mdm) mice severely affects skeletal muscle, but not the heart. Circulation Research.  ISSN 0009-7330.  115
  • Melleby, Arne Olav; Strand, Mari Elen; Skrbic, Biljana; Dahl, Christen Peder; Tønnessen, Theis; Sjaastad, Ivar; Fiane, Arnt E; Filmus, J.; Christensen, Geir Arve & Lunde, Ida Gjervold (2014). Glypican 6 is up-regulated in pressure overload induced pathological left ventricular remodeling, mediates bFGF signaling and may affect cardiac fibrosis development.
  • Melleby, Arne Olav; Strand, Mari Elen; Skrbic, Biljana; Dahl, Christen Peder; Tønnessen, Theis; Sjaastad, Ivar; Fiane, Arnt; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2014). The heparan sulfate proteoglycan glypican-6 is increased in experimental and clinical heart failure and might play a role in myocardial fibrosis. European Journal of Heart Failure.  ISSN 1388-9842.  16, s 116- 116
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Høiseth, Arne Didrick; Brynildsen, Jon; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Chromogranin A directly modifies cardiomyocyte Ca2+ homeostasis via CaMKII inhibition and is a strong prognostic biomarker in acute heart failure.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Stridsberg, Mats; Høiseth, Arne Didrik; Brynildsen, Jon; Moe, Morten Kaare; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Chromogranin A is a potent risk marker in acute heart failure and directly associated with cardiomyocyTe Ca2+ handling. European Heart Journal.  ISSN 0195-668X.  35, s 328- 328
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2014). Secretoneurin provides independent prognostic information in patients with heart failure and cardiac arrest, and has a direct inhibitory effect on diastolic Ca2+ leak and arrhythmogenic Ca2+ waves via CaMKII inhibition. Circulation Research.  ISSN 0009-7330.  115
Publisert 13. apr. 2011 11:37 - Sist endret 8. juni 2011 08:29