Jürgen Geisler

Bilde av Jürgen Geisler
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Brukernavn
Besøksadresse Sykehusveien 25 None 1474 NORDBYHAGEN

Publikasjoner

  • Aure, Miriam Ragle; Vitelli, Valeria; Jernström, Sandra Johanna; Kumar, Surendra; Krohn, Marit; Due, Eldri Undlien; Haukaas, Tonje Husby; Leivonen, Suvi-Katri; Vollan, Hans Kristian Moen; Luders, Torben; Rødland, Einar Andreas; Vaske, Charles; Zhao, Wei; Møller, Elen Kristine; Nord, Silje; Giskeødegård, Guro F.; Bathen, Tone Frost; Caldas, Carlos; Tramm, Trine; Alsner, Jan; Overgaard, Jens; Geisler, Jürgen; Bukholm, Ida Rashida Khan; Naume, Bjørn; Schlichting, Ellen; Sauer, Torill; Mills, Gordon B.; Kåresen, Rolf; Mælandsmo, Gunhild; Lingjærde, Ole Christian; Frigessi, Arnoldo; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise; Sahlberg, Kristine Kleivi & OSBREAC, Oslo Breast Cancer Consortium (2017). Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome. Breast Cancer Research.  ISSN 1465-542X.  19(44) . doi: 10.1186/s13058-017-0812-y Fulltekst i vitenarkiv.
  • Daldorff, Stine; Mathiesen, Randi R.; Yri, Olav Erich; Ødegård, Hilde Presterud & Geisler, Jürgen (2017). Cotargeting of CYP-19 (aromatase) and emerging, pivotal signalling pathways in metastatic breast cancer. British Journal of Cancer.  ISSN 0007-0920.  116, s 10- 20
  • Daldorff, Stine; Ruud, Randi Margit; Yri, Olav Erich; Ødegård, Hilde Presterud & Geisler, Jürgen (2017). Cotargeting of CYP-19 (aromatase) and emerging, pivotal signaling pathways in metastatic breast cancer. British Journal of Cancer.  ISSN 0007-0920.  116(1), s 10- 20 . doi: 10.1038/bjc.2016.405
  • Flågeng, Marianne Hauglid; Larionov, Alexey; Geisler, Jürgen; Knappskog, Stian; Prestvik, Wenche S; Bjørkøy, Geir; Lilleng, Peer Kåre; Dixon, JM; Miller, WR; Lønning, Per Eystein & Mellgren, Gunnar (2017). Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin-1 in ER positive/HER-2/neu non-amplified primary breast cancers. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  165, s 228- 235
  • Rahbar, Afsar; Touma, Joel; Costa, Helena; Davoudi, Belghis; Bukholm, Ida Rashida Khan; Sauer, Torill; Vetvik, Katja K; Geisler, Jürgen & Söderberg-Naucler, Cecilia (2017). Low Expression of Estrogen Receptor-α and Progesterone Receptor in Human Breast Cancer Tissues Is Associated With High-Grade Human Cytomegalovirus Protein Expression. Clinical Breast Cancer.  ISSN 1526-8209.  17(7), s 526- 535.e1 . doi: 10.1016/j.clbc.2017.04.013
  • Flågeng, Marianne Hauglid; Larionov, Alexey; Geisler, Jürgen; Knappskog, Stian; Prestvik, Wenche S; Bjørkøy, Geir; Lilleng, Peer Kåre; Dixon, JM; Miller, William R.; Lønning, Per Eystein & Mellgren, Gunnar (2016). Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  165, s 228- 235 . doi: 10.1016/j.jsbmb.2016.06.011
  • Gulati, Geeta; Heck, Siri Lagethon; Ree, Anne Hansen; HOFFMANN, PAVEL; Schulz-Menger, Jeanette; Fagerland, Morten; Gravdehaug, Berit; von Knobelsdorff-Brenkenhoff, Florian; Bratland, Åse; Storås, Tryggve; Hagve, Tor-Arne; Røsjø, Helge; Steine, Kjetil; Geisler, Jürgen & Omland, Torbjørn (2016). Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 x 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol. European Heart Journal.  ISSN 0195-668X.  37(21), s 1671- 1680 . doi: 10.1093/eurheartj/ehw022
  • Sas-Chen, Aldema; Aure, Miriam Ragle; Leibovich, Limor; Carvalho, Silvia; Enuka, Yehoshua; Körner, Cindy; Polycarpou-Schwarz, Maria; Lavi, Sara; Nevo, Nava; Kuznetsov, Yuri; Yuan, Justin; Azuaje, Francisco; Ulitsky, Igor; Diederichs, Sven; Wiemann, Stefan; Yakhini, Zohar; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise; Yarden, Yosef; Sauer, Torill; Geisler, Jürgen; Hofvind, Solveig; Bathen, Tone Frost; Borgen, Elin; Engebråten, Olav; Fodstad, Øystein; Garred, Øystein; Geitvik, Gry; Kåresen, Rolf; Naume, Bjørn; Mælandsmo, Gunhild; Russnes, Hege Elisabeth Giercksky; Schlichting, Ellen; Sørlie, Therese; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Skjerven, Helle & Fritzman, Britt (2016). LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  8(9), s 1052- 1064 . doi: 10.15252/emmm.201606198 Fulltekst i vitenarkiv.
  • Bemanian, Vahid; Sauer, Torill; Touma, Joel; Lindstedt, Bjørn-Arne; Chen, Ying; Ødegård, Hilde Presterud; Vetvik, Katja K; Bukholm, Ida Rashida Khan & Geisler, Jürgen (2015). The epidermal growth factor receptor (EGFR / HER-1) gatekeeper mutation T790M is present in European patients with early breast cancer. PLoS ONE.  ISSN 1932-6203.  10:e0134398(8) . doi: 10.1371/journal.pone.0134398
  • Lauss, Martin; Haq, Rizwan; Cirenajwis, Helena; Phung, Bengt; Harbst, Katja; Staaf, Johan; Rosengren, Frida; Holm, Karolina; Aine, Mattias; Jirström, Karin; Borg, Åke; Busch, Christian; Geisler, Jürgen; Lønning, Per Eystein; Ringnér, Markus; Howlin, Jillian; Fisher, David E & Jönsson, Göran (2015). Genome-wide DNA methylation analysis in melanoma reveals the importance of CpG methylation in MITF regulation. Journal of Investigative Dermatology.  ISSN 0022-202X.  135(7), s 1820- 1828 . doi: 10.1038/jid.2015.61
  • Lauss, Martin; Ringnér, Markus; Karlsson, Anna; Harbst, Katja; Busch, Christian; Geisler, Jürgen; Lønning, Per Eystein; Staaf, Johan & Jönsson, Göran (2015). DNA methylation subgroups in melanoma are associated with proliferative and immunological processes. BMC Medical Genomics.  ISSN 1755-8794.  8:73, s 1- 11 . doi: 10.1186/s12920-015-0147-4
  • Løes, Inger Marie; Immervoll, Heike; Angelsen, Jon-Helge; Horn, Arild; Geisler, Jürgen; Busch, Christian; Lønning, Per Eystein & Knappskog, Stian (2015). Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimen. Tumour Biology.  ISSN 1010-4283.  36(2), s 1003- 1013 . doi: 10.1007/s13277-014-2711-5 Fulltekst i vitenarkiv.
  • Ree, Anne Hansen; Flatmark, Kjersti; Sælen, Marie Grøn; Folkvord, Sigurd; Dueland, Svein; Geisler, Jürgen & Redalen, Kathrine Røe (2015). Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: Opportunities for signaling-adapted therapies. Critical reviews in oncology/hematology.  ISSN 1040-8428.  95(1), s 114- 124 . doi: 10.1016/j.critrevonc.2015.01.003
  • Tahiri, Andliena; Leivonen, Suvi-Katri; Luders, Torben; Stenfeld, Israel; Aure, Miriam Ragle; Geisler, Jürgen; Mäkelä, Rami; Riis, Margit; Nord, Silje H.; Yakhini, Zohar; Sahlberg, Kristine Kleivi; Børresen-Dale, Anne-Lise; Perälä, Merja; Bukholm, Ida Rashida Khan & Kristensen, Vessela N. (2014). Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors. Carcinogenesis.  ISSN 0143-3334.  35(1), s 76- 85 . doi: 10.1093/carcin/bgt333
  • Birkeland, Einar Elvbakken; Busch, Christian; Berge, Elisabet Ognedal; Geisler, Jürgen; Jonsson, Göran; Lillehaug, Johan R.; Knappskog, Stian & Lønning, Per Eystein (2013). Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma. Clinical and Experimental Metastasis.  ISSN 0262-0898.  30(7), s 867- 876 . doi: 10.1007/s10585-013-9587-4
  • Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari & Akslen, Lars A. (2013). Malignt melanom – diagnostikk, behandling og oppfølging i Norge. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  133(20), s 2154- 2159 . doi: 10.4045/tidsskr.12.1416
  • Gulati, Geeta; Heck, Siri Lagethon; Ree, Anne Hansen; Gravdehaug, Berit; Røsjø, Helge; Steine, Kjetil; Bratland, Åse; HOFFMANN, PAVEL; Geisler, Jürgen & Omland, Torbjørn (2013). Cardioprotective treatment during adjuvant cancer therapy. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  133(17), s 1832- 1836 . doi: 10.4045/tidsskr.12.1514
  • Tahiri, Andliena; Røe, Kathrine; Ree, Anne Hansen; de Wijn, Rik; Risberg, Karianne; Busch, Christer; Lønning, Per Eystein; Kristensen, Vessela N. & Geisler, Jürgen (2013). Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma. PLoS ONE.  ISSN 1932-6203.  8(8) . doi: 10.1371/journal.pone.0072692
  • Geisler, Jürgen; Smith, Ian & Miller, William (2012). Presurgical (neoadjuvant) endocrine therapy is a useful model to predict response and outcome to endocrine treatment in breast cancer patients. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  131(3-5), s 93- 100 . doi: 10.1016/j.jsbmb.2011.12.006
  • Harbst, Katja; Staaf, Johan; Lauss, Martin; Karlsson, Anna; Måsbäck, A; Johansson, Iva; Bendahl, Pär-Ola; Vallon-Christersson, Johan; Törngren, Therese; Ekedahl, Henrik; Geisler, Jürgen; Höglund, Mattias; Ringnér, Markus; Lundgren, Lotta; Jirström, Karin; Olsson, Håkan; Ingvar, Christian; Borg, Åke; Tsao, Hensin & Jonsson, Göran (2012). Molecular Profiling Reveals Low- and High-Grade Forms of Primary Melanoma. Clinical Cancer Research.  ISSN 1078-0432.  18(15), s 4026- 4036 . doi: 10.1158/1078-0432.CCR-12-0343
  • Heck, Siri Lagethon; Gulati, Geeta; Ree, Anne Hansen; Schulz-Menger, Jeanette; Gravdehaug, Berit; Røsjø, Helge; Steine, Kjetil; Bratland, Åse; HOFFMANN, PAVEL; Geisler, Jürgen & Omland, Torbjørn (2012). Rationale and Design of the Prevention of Cardiac Dysfunction during an Adjuvant Breast Cancer Therapy (PRADA) Trial. Cardiology.  ISSN 0008-6312.  123(4), s 240- 247 . doi: 10.1159/000343622
  • Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A. & Straume, Oddbjørn (2012). Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLoS ONE.  ISSN 1932-6203.  7(6) . doi: 10.1371/journal.pone.0038364
  • Geisler, Jürgen (2011). Differences between the non-steroidal aromatase inhibitors anastrozole and letrozole - of clinical importance?. British Journal of Cancer.  ISSN 0007-0920.  104(7), s 1059- 1066 . doi: 10.1038/bjc.2011.58
  • Geisler, Jürgen; Sasano, Hironobu; Chen, Shiuan & Purohit, Atul (2011). Steroid sulfatase inhibitors: Promising new tools for breast cancer therapy?. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  125(1-2), s 39- 45 . doi: 10.1016/j.jsbmb.2011.02.002
  • Syversen, Unni; Halse, Johan I.; Geisler, Jürgen & Eriksen, Erik Fink (2011). Denosumab for behandling av postmenopausal osteoporose. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  131(19), s 1893- 1896 . doi: 10.4045/tidsskr.10.1116
  • Geisler, Jurgen; Suzuki, Takashi; Helle, Hildegunn; Miki, Yasuhiro; Nagasaki, Shuji; Duong, Nhat Kim; Ekse, Dagfinn; Aas, Turid; Evans, Dean B.; Lønning, Per Eystein & Sasano, Hironobu (2010). Breast cancer aromatase expression evaluated by the novel antibody 677: Correlations to intra-tumor estrogen levels and hormone receptor status. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  118(4-5), s 237- 241 . doi: 10.1016/j.jsbmb.2009.10.010
  • Busch, Christian; Geisler, Jürgen; Lillehaug, Johan R. & Lønning, Per Eystein (2010). MGMT expression levels predict disease stabilisation, progression-free and overall survival in patients with advanced melanomas treated with DTIC. European Journal of Cancer.  ISSN 0959-8049.  46(11), s 2127- 2133 . doi: 10.1016/j.ejca.2010.04.023
  • Geisler, Jurgen & Lønning, Per Eystein (2010). Impact of aromatase inhibitors on bone health in breast cancer patients. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  118(4-5), s 294- 299 . doi: 10.1016/j.jsbmb.2009.10.004
  • Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin & Lien, Ernst Asbjørn (2010). Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer. BMC Cancer.  ISSN 1471-2407.  10 . doi: 10.1186/1471-2407-10-313
  • Haynes, Ben P.; Straume, Anne Hege; Geisler, Jurgen; A'Hern, Roger; Helle, Hildegunn; Smith, Ian E; Lønning, Per Eystein & Dowsett, Mitch (2010). Intratumoral estrogen disposition in breast cancer. Clinical Cancer Research.  ISSN 1078-0432.  16(6), s 1790- 1801 . doi: 10.1158/1078-0432.CCR-09-2481
  • Jönsson, Göran; Busch, Christian; Knappskog, Stian; Geisler, Jürgen; Miletic, Hrvoje; Ringnér, Markus; Lillehaug, Johan R.; Borg, Åke & Lønning, Per Eystein (2010). Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome. Clinical Cancer Research.  ISSN 1078-0432.  16(13), s 3356- 3367 . doi: 10.1158/1078-0432.CCR-09-2509
  • Lønning, Per Eystein & Geisler, Jürgen (2010). Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: Of relevance to clinical understanding?. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  118(4-5), s 288- 293 . doi: 10.1016/j.jsbmb.2009.09.013
  • Flageng, MH; Hauglid, Marianne; Moi, Line Leonore Haugan; Dixon, J. Michael; Geisler, Jurgen; Lien, Ernst Asbjørn; Miller, William Russell; Lonning, PE; Lønning, Per Eystein & Mellgren, Gunnar (2009). Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. British Journal of Cancer.  ISSN 0007-0920.  101(8), s 1253- 1260 . doi: 10.1038/sj.bjc.6605324
  • Lønning, Per Eystein; Helle, Hildegunn; Duong, Nhat Kim; Ekse, Dagfinn; Aas, T & Geisler, Jurgen (2009). Tissue estradiol is selectively elevated in receptor positive breast cancers while tumour estrone is reduced independent of receptor status. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  117(1-3), s 31- 41 . doi: 10.1016/j.jsbmb.2009.06.005
  • Geisler, Jurgen; Helle, Hildegunn; Ekse, Dagfinn; Ekse, D.; Duong, Nhat Kim; Evans, Dean B.; Nordbø, Yngve; Aas, Turid & Lønning, Per Eystein (2008). Letrozole is Superior to Anastrozole in Suppressing Breast Cancer Tissue and Plasma Estrogen Levels. Clinical Cancer Research.  ISSN 1078-0432.  14(19), s 6330- 6335 . doi: 10.1158/1078-0432.CCR-07-5221 Vis sammendrag
  • Geisler, Jurgen; Ekse, Dagfinn; Helle, Hildegunn; Duong, Nhat Kim & Lønning, Per Eystein (2008). An optimised, highly sensitive radioimmunoassay for the simultaneous measurement of estrone, estradiol and estrone sulfate in the ultra-low range in human plasma samples. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  109(1-2), s 90- 95 . doi: 10.1016/j.jsbmb.2007.12.011
  • Lonning, PE & Geisler, Jürgen (2008). Experience with exemestane in the treatment of early and advanced breast cancer. Expert Opinion on Drug Metabolism & Toxicology.  ISSN 1742-5255.  4(7), s 987- 997 . doi: 10.1517717425250802204142
  • Lønning, Per Eystein & Geisler, Jurgen (2008). Aromatase inhibitors: Assessment of biochemical efficacy measured by total body aromatase inhibition and tissue estrogen suppression. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  108(3-5), s 196- 202 . doi: 10.1016/j.jsbmb.2007.09.017
  • Lønning, Per Eystein & Geisler, Jurgen (2008). Experience with exemestane in the treatment of early and advanced breast cancer. Expert Opinion on Drug Metabolism & Toxicology.  ISSN 1742-5255.  4(7), s 987- 997 . doi: 10.1517/17425250802204142
  • Lønning, Per Eystein & Geisler, Jurgen (2008). Indications and limitations of third-gene ration aromatase inhibitors. Expert Opinion on Investigational Drugs.  ISSN 1354-3784.  17(5), s 723- 739 . doi: 10.1517/13543780802041751
  • Geisler, Jurgen; Haynes, Ben; Ekse, Dagfinn; Dowsett, Mitch & Lønning, Per Eystein (2007). Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  104(1-2), s 27- 34 . doi: 10.1016/j.jsbmb.2006.09.040
  • Lønning, Per Eystein & Geisler, Jurgen (2007). Aromatase inhibitors-Socioeconomical issues. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  106(1-5), s 55- 61 . doi: 10.1016/j.jsbmb.2007.05.002
  • Geisler, Jürgen & Lønning, Per Eystein (2006). Aromatase inhibitors as adjuvant treatment of breast cancer. Critical reviews in oncology/hematology.  ISSN 1040-8428.  57(1), s 53- 61
  • Geisler, J; Lønning, Per Eystein; Krag, LE; Løkkevik, Erik; Løkkevik, Erik; Risberg, Terje; Hagen, AI; Schlichting, E; Lien, EA; Ofjord, ES; Øfjord, Erik S.; Eide, GE; Di Salle, Enrico; Polli, A; di Salle, E & Paolini, J (2006). Changes in bone and lipid metabolism in postmenopausal women with early breast cancer after terminating 2-year treatment with exemestane: A randomised, placebo-controlled study. European Journal of Cancer.  ISSN 0959-8049.  42(17), s 2968- 75
  • Geisler, Jürgen & Lønning, Per Eystein (2006). Clinical pharmacology of aromatase inhibitors, In BJA Furr (ed.),  Milestones in Drug Therapy: Aromatase Inhibitors.  Birkhäuser Verlag.  ISBN 3764371994.  3.  s 45 - 52
  • Knappskog, Stian; Geisler, Jürgen; Arnesen, Thomas; Lillehaug, Johan & Lønning, Per Eystein (2006). A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family. Genes, Chromosomes and Cancer.  ISSN 1045-2257.  45(12), s 1155- 1163 . doi: 10.1002
  • Lønning, Per Eystein & Geisler, Jürgen (2006). Commentary on: Does adjuvant therapy with letrozole improve survival in postmenopausal women with early-stage breast cancer?. Nature Clinical Practice Oncology.  ISSN 1743-4254.  3(7), s 356- 357 Vis sammendrag
  • Kristensen, Vessela Nedelcheva; Sørlie, Therese; Sorlie, Therese; Geisler, Jürgen; Geisler, E; Yoshimura, Noriko; Lingjærde, Ole Christian; Linegjaerde, Ole-Christian; Glad, Ingrid; Frigessi, Arnoldo; Harada, Nobuhiro; Lonning, PE; Lønning, Per Eystein & Børresen-Dale, Anne-Lise (2005). Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  95(1-5), s 105- 111 . doi: 10.1016/j.jsbmb.2005.04.028
  • Lønning, Per Eystein & Geisler, Jürgen (2005). Aromatase inhibitors - socio-economical issues. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  95(1-5), s 137- 142 . doi: 10.1016/j.jsbmb.2005.04.006
  • Geisler, Jürgen (2003). Aromatase inhibitors and inactivators for the treatment of postmenopausal breast cancer: A review. Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents.  ISSN 1568-0134.  3, s 261- 276
  • Geisler, Stephanie; Børresen-Dale, Anne-Lise; Johnsen, Hilde; Aas, Turid; Geisler, Jürgen; Akslen, Lars A.; Anker, Gun & Lønning, Per Eystein (2003). TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer. Clinical Cancer Research.  ISSN 1078-0432.  9, s 5582- 5588
  • Lønning, Per Eystein; Geisler, Jürgen & Bhatnager, Ajay (2003). Development of aromatase inhibitors and their pharmacologic profile. American Journal of Clinical Oncology.  ISSN 0277-3732.  26(4), s S3- S8 Vis sammendrag
  • Geisler, Jürgen; Dowsett, Mitch & Lønning, Per Eystein (2002). Letrozole is more effective than anastrozole in suppressing total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients. American Journal of Oncology Review.  ISSN 1542-9520.  1(2), s 99- 102
  • Geisler, Jürgen; Haynes, Ben; Anker, Gun; Dowsett, Mitch & Lønning, Per Eystein (2002). Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. Journal of Clinical Oncology.  ISSN 0732-183X.  20(3), s 751- 757 Vis sammendrag
  • Geisler, Jürgen; Detre, Simone; Berntsen, Hildegunn; Ottestad, Lars; Lindtjørn, Bernt; Dowsett, Mitch & Lønning, Per Eystein (2001). Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer. Clinical Cancer Research.  ISSN 1078-0432.  7, s 1230- 1236 Vis sammendrag
  • Geisler, Jürgen & Lønning, Per Eystein (2001). Resistance to Endocrine Therapy of Breast Cancer: Recent Advances and Tomorrow`s Challenges. Clinical Breast Cancer.  ISSN 1526-8209.  s 297- 308
  • Helle, Svein Inge; Geisler, Jürgen; Anker, Gun; Leirvaag, B.; Holly, Jeffrey M.P. & Lønning, Per Eystein (2001). Alterations in the insulin-like growth factor-system during treatment with diethylstilbestrol in patients with metastatic breast cancer. British Journal of Cancer.  ISSN 0007-0920.  85, s 147- 151
  • Lønning, Per Eystein; Geisler, Jürgen; Johannessen, Dag Clement; Gschwind, Hans-Peter; Waldmeier, Felix; Schneider, Werner; Galli, Bruno; Winkler, Tammo; Blum, Wolfgang; Kriemler, Hans-Peter; Miller, William Russell & Faigle, Johann Werner (2001). Pharmacokinetics and metabolism of formestane in breast cancer patients. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  77(1), s 39- 47 Vis sammendrag
  • Lønning, Per Eystein; Kragh, L. E.; Erikstein, B.; Hagen, A.; Risberg, T.; Schlichting, E. & Geisler, Jürgen (2001). The potential for aromatase inhibition in breast cancer prevention. Clinical Cancer Research.  ISSN 1078-0432.  s 4423- 4428
  • Geisler, Jürgen (2000). Arimidex - direkte Wirkung auf Tumoröstrogenspiegel, I: [Mangler fornavn] [Mangler etternavn] (red.),  Aktuelle Onkologie.  Zuckschwerdt Verlag.  s 9 - 15
  • Geisler, Jürgen (2000). Arimidex - direkte Wirkung auf Tumoröstrogenspiegel, I: [Mangler fornavn] [Mangler etternavn] (red.),  Aktuelle Onkologie.  Zuckschwerdt Verlag.  s 9 - 15
  • Geisler, Jürgen; Berntsen, Hildegunn & Lønning, Per Eystein (2000). A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  72, s 259- 264
  • Geisler, Jürgen; Berntsen, Hildegunn & Lønning, Per Eystein (2000). A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  72, s 259- 264

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  • Mellgren, Gunnar; Angelsen, Anders; Eikesdal, Hans Petter & Geisler, Jürgen (2016). MEDIKAMENTELL KREFTBEHANDLING - CYTOSTATIKABOKEN Kapittel 19 - Hormoner og antihormoner. Universitetet i Oslo, Det medisinske fakultet, Institutt for klinisk medisin, Avdeling for farmakologi.  ISBN 978-82-992331-4-9.  661 s.
  • Straume, Oddbjørn; Geisler, Jürgen; Gullestad, Hans Petter; Nyakas, Marta Sølvi; Jacobsen, Kari Dolven & Aamdal, Steinar (2016). MEDIKAMENTELL KREFTBEHANDLING - Cytostatikaboken 8. utgave, Kapittel 34 - Malignt melanom. Universitetet i Oslo, Det medisinske fakultet, Institutt for klinisk medisin, Avdeling for farmakologi.  ISBN 978-82-992331-4-9.  661 s.

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  • Bemanian, Vahid; Sauer, Torill; Touma, Joel; Vetvik, Katja K; Chen, Ying; Kristensen, Vessela N.; Bukholm, Ida Rashida Khan & Geisler, Jürgen (2016). Next generation sequencing (NGS) reveals high mutation rates in established and potentially novel cancer genes in triple-negative breast cancer. Cancer Research.  ISSN 0008-5472.  76 . doi: 10.1158/1538-7445.AM2016-LB-246
  • Bemanian, Vahid; Sauer, Torill; Touma, Joel; Vetvik, Katja K; Kristensen, Vessela N.; Bukholm, Ida Rashida Khan & Geisler, Jürgen (2016). Next generation sequencing (NGS) reveals high mutation rates in all established breast cancer subtypes with type-specific patterns.
  • Costa, Helena; Touma, Joel; Davoudi, B; Geisler, Jürgen; Vetvik, Katja K; Söderberg Naucler, Cecilia & Rahbar, Afsar (2016). High-grade human cytomegalovirus IEA is associated with expression of COX-2 and 5-LO in human breast cancer samples.
  • Gulati, Geeta; Heck, Siri Lagethon; Geisler, Jürgen; Fagerland, Morten; HOFFMANN, PAVEL; Gravdehaug, Berit; Steine, Kjetil; Ree, Anne Hansen; Røsjø, Helge & Omland, Torbjørn (2016). Effect of candesartan and metoprolol on subclinical myocardial injury during anthracycline therapy: data from the prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA) study.
  • Gulati, Geeta; Heck, Siri Lagethon; Geisler, Jürgen; Gravdehaug, Berit; HOFFMANN, PAVEL; Steine, Kjetil; Ree, Anne Hansen; Røsjø, Helge & Omland, Torbjørn (2016). Troponin I and Cardiac Function During Breast Cancer Therapy in Human Epidermal Growth Factor Receptor 2 Positive and Negative Patients: Results from the PRADA Study.
  • Gulati, Geeta; Heck, Siri Lagethon; Geisler, Jürgen; Gravdehaug, Berit; Ree, Anne Hansen; HOFFMANN, PAVEL; Røsjø, Helge; Omland, Torbjørn & Steine, Kjetil (2016). Atrio-ventricular plane excursion is impaired after ten weeks of anthracycline treatment in breast cancer patients; Data from the PRADA-study.
  • Gulati, Geeta; Heck, Siri Lagethon; HOFFMANN, PAVEL; Ree, Anne Hansen; Schulz-Menger, Jeanette; von Knobelsdorff-Brenkenhoff, Florian; Steine, Kjetil; Bratland, Åse; Gravdehaug, Berit; Røsjø, Helge; Geisler, Jürgen & Omland, Torbjørn (2016). Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): Primary Results of a Randomized, 2 x 2 Factorial, Placebo-Controlled, Double-Blind Clinical Trial. Circulation.  ISSN 0009-7322.
  • Heck, Siri Lagethon; Gulati, Geeta; HOFFMANN, PAVEL; von Knobelsdorff-Brenkenhoff, Florian; Storås, Tryggve; Ree, Anne Hansen; Gravdehaug, Berit; Røsjø, Helge; Steine, Kjetil; Geisler, Jürgen & Omland, Torbjørn (2016). Effects of Candesartan and Metoprolol on Myocardial Mass, Edema, and Fibrosis During Anthracycline Treatment in Early Breast Cancer: APRADA-CMR substudy.
  • McNamara, Keely; Guestini, F; Sauer, Torill; Lindstrøm, Jonas Christoffer; Sasano, Hironobu & Geisler, Jürgen (2016). Steroid receptors and steroidogenic enzymes in human breast cancer: Associations with breast cancer subtypes and clinical outcome.
  • Rahbar, Afsar; Touma, Joel; Costa, Helena; Davoudi, B; Vetvik, Katja K; Geisler, Jürgen & Söderberg Naucler, Cecilia (2016). Low expression levels of hormone receptors (ER-alpha and PGR) in human breast cancer samples is significantly associated with high-grade human cytomegalovirus-IEA.
  • Bemanian, Vahid; Sauer, Torill; Touma, Joel; Lindstedt, Bjørn-Arne; Chen, Ying; Ødegård, Hilde Presterud; Bukholm, Ida Rashida Khan & Geisler, Jürgen (2015). The EGFR gatekeeper mutation T790M is present in selected patients with early breast cancer. Proceedings of the American Association of Cancer Research.  ISSN 0197-016X.  56(1), s 28- 29
  • Gulati, Geeta; Heck, Siri Lagethon; Ree, Anne Hansen; Bratland, Åse; Steine, Kjetil; Schulz-Menger, Jeanette; Gravdehaug, Berit; HOFFMANN, PAVEL; Røsjø, Helge; Geisler, Jürgen & Omland, Torbjørn (2015). Abstract CT321: Prevention of cardiac dysfunction during adjuvant breast cancer therapy: the PRADA study. Cancer Research.  ISSN 0008-5472.
  • Ree, Anne Hansen; Flatmark, Kjersti; Sælen, Marie Grøn; Folkvord, Sigurd; Dueland, Svein; Geisler, Jürgen & Redalen, Kathrine Røe (2015). High tumor PI3K signaling in resistance to chemoradiotherapy and metastatic dissemination of locally advanced rectal cancer. Molecular Cancer Therapeutics.  ISSN 1535-7163.  14(7)
  • Tahiri, Andliena; De Wijn, Rik; Venkata, Satheesh; Luders, Torben; Aure, Miriam Ragle; Quigley, David; Hurtado, Antoni; Kristensen, Vessela N. & Geisler, Jürgen (2015). Protein Tyrosine Kinase Activity and miRNA Expression Profiling Reveals Differences According to Progesterone-Receptor-Status in HER2 Negative Breast Cancer.
  • Geisler, Jürgen (2014). Norsk Melanom Gruppe (NMG) svarer:. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  134(1), s 9 . doi: 10.4045/tidsskr.13.1569
  • Geisler, Jürgen (2014). Norsk Melanom Gruppe (NMG) svarer:. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  134(1), s 8 . doi: 10.4045/tidsskr.13.1567
  • Flågeng, Marianne Hauglid; Larionov, Alexey; Geisler, Jürgen; Dixon, JM; Lønning, Per Eystein & Mellgren, Gunnar (2012). Inverse regulation of Neuregulin 1 and HER-3 during treatment with aromatase inhibitors of estrogen receptor-positive breast cancer.
  • Geisler, Jürgen & Sasano, Hironobu (2012). Special issue on Steroids and Cancer Preface. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  131(3-5), s 67- 67 . doi: 10.1016/j.jsbmb.2012.05.009
  • Tahiri, Andliena; Røe, Kathrine; de Wijn, Rik; Busch, Christian; Lønning, Per Eystein; Ree, Anne Hansen; Kristensen, Vessela N. & Geisler, Jürgen (2012). Tyrosine kinase activity profiling of metastatic malignant melanoma: Identification of possible therapeutic targets and markers predicting response to therapy. Vis sammendrag
  • Busch, Christian; Geisler, Jürgen; Knappskog, Stian; Lillehaug, Johan R. & Lønning, Per Eystein (2010). Alterations in the p53 Pathway and p16INK4a Expression Predict Overall Survival in Metastatic Melanoma Patients Treated with Dacarbazine. Journal of Investigative Dermatology.  ISSN 0022-202X.  130(10), s 2514- 2516 . doi: 10.1038/jid.2010.138
  • Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin & Lien, Ernst Asbjørn (2010). Effects of CYP2C19 genotype on tamoxifen and estrogen metabolism. European Journal of Cancer.  ISSN 0959-8049.  8(5), s 60- 60
  • Flågeng, Marianne Hauglid; Moi, Line Leonore Haugan; Dixon, J. Michael; Geisler, Jürgen; Lien, Ernst Asbjørn; Miller, William R.; Lønning, Per Eystein & Mellgren, Gunnar (2009). HER-2/neu and nuclear receptor coactivators are upregulated in breast cancer tumors during estrogen deprivation.
  • Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Lønning, Per Eystein & Lien, Ernst Asbjørn (2009). Relations between FSH, SHBG and tamoxifen metabolism during steady state tamoxifen treatment.
  • Hans, Volkmar; Evans, D; Evans, Dean B.; Lønning, Per Eystein & Geisler, Jurgen (2009). Proteomics analysis of tissue samples obtained before and during letrozole treatment in postmenopausal patients with locally advanced breast cancer. Cancer Research.  ISSN 0008-5472.  69(2), s 214S- 214S
  • Haynes, B; Straume, Anne Hege; Geisler, Jurgen; Ahern, R; Lønning, Per Eystein; Lonning, PE & Dowsett, M (2009). DETERMINANTS OF INTRATUMOURAL OESTRADIOL (E2) CONCENTRATIONS IN POSTMENOPAUSAL BREAST CANCER: ROLES FOR OESTROGEN RECEPTOR (ER) AND 17B-HYDROXYSTEROID DEHYDROGENASE 7 (HSD17B7). Annals of Oncology.  ISSN 0923-7534.  20, s 51- 52
  • Gjerde, Jennifer Fernandez; Geisler, Jurgen; Lundgren, Steinar; Ekse, Dagfinn; Breilid, Harald; Hauglid, Marianne; Hauglid, M; Varhaug, EJ; Varhaug, Jan Erik; Steen, Vidar Martin; Lønning, Per Eystein; Lonning, PE & Lien, Ernst Asbjørn (2008). A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment. Breast Cancer Research and Treatment.  ISSN 0167-6806.  109(3), s 592- 592
  • Hauglid, Marianne; Moi, Line Leonore Haugan; Dixon, Michael; Geisler, Jurgen; Miller, William R.; Lien, Ernst Asbjørn; Lønning, Per Eystein & Mellgren, Gunnar (2008). Changes in mRNA expression levels of steroid receptor coactivators correlate with treatment response to aromatase inhibition in human breast cancer.
  • Busch, Christian; Geisler, Jurgen; Lillehaug, Johan R. & Lønning, Per Eystein (2007). Promotor hypermethylation of MGMT, RAR-beta2, RASSF1A and p16 in metastatic malignant melanoma. Proceedings of the American Association of Cancer Research.  ISSN 0197-016X.  48, s 684
  • Gjerde, Jennifer Fernandez; Geisler, Jurgen; Lundgren, Steinar; Ekse, Dagfinn; Breilid, Harald; Hauglid, Marianne; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin; Lønning, Per Eystein & Lien, Ernst Asbjørn (2007). A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment. Breast Cancer Research and Treatment.  ISSN 0167-6806.  S106
  • Staalesen, Vidar; Knappskog, Stian; Chrisanthar, Ranjan; Geisler, Stephanie; baumbusch, lars; Løkkevik, Erik; Østenstad, Bjørn; Geisler, Jurgen; Børresen-Dale, Anne-Lise; Lillehaug, Johan & Lønning, Per Eystein (2007). The MDM2 SNP309 G/T promoter polymorphism is associated with chemoresistance in primary breast cancers harbouring mutations in the TP53 gene.
  • Lønning, Per Eystein & Geisler, Jürgen (2006). Does adjuvant therapy with letrozole improve survival in postmenopausal women with early-stage breast cancer?. Nature Clinical Practice Oncology.  ISSN 1743-4254.  3(7; doi:10.1038/ncponc0537), s 356- 367
  • Geisler, Jürgen (2003). Breast cancer tissue estrogens and their manipulation with aromatase inhibitors and inactivators.
  • Lønning, Per Eystein; Geisler, Jürgen & Dowsett, Mitch (2002). Endocrine effects of nonsteriodal aromatase inhibitors and their clinical impact. Journal of Clinical Oncology.  ISSN 0732-183X.  20, s 3039- 2040
  • Geisler, Jürgen (2002). Aromatase Inhibition in Postmenopausal Breast Cancer Patients. Dr.philos.. -.
  • Geisler, Jürgen; Berntsen, Hildegunn; Ottestad, J; Lindtjørn, Bernt; Dowsett, Mitch & Lønning, Per Eystein (1999). Comparison of the effects of neoadjuvant 'Arimidex'(Anastrozole) on plasma and intra-tumor tissue estrogen levels in postmenopausalbreast cancer patients.

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Publisert 13. apr. 2011 11:38 - Sist endret 19. juni 2017 14:51

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