Oleksandr Frei

Bilde av Oleksandr Frei
English version of this page
Brukernavn
Besøksadresse Oslo Universitetssykehus Ullevål Bygg 48
Postadresse OUS, Postboks 4956 Nydalen 0424 Oslo
Andre tilknytninger Senter for presisjonspsykiatri

Foto: Kirsten Sjøwall

 

Jeg jobber som postdoktor i NORMENT (Norwegian Centre for Mental Disorders Research), Det medisinske fakultet, UiO. Vi forsker på mentale lidelser, og prøver å finne de sjeldne genetiske varianter som er assosiert med den skjulte arvbarheten av schizofreni.

Jeg har en doktorgrad innenfor matematikk og machine learning (Moscow Institute of Physics and Technology, 2013). Til gjengjeld har jeg bred erfaring innen software unvikling (Search Engine for Sharepoint, Microsoft, 2010-2013; Petrel E&P Software Platform for seismic to simulation reservoir engineering, Schlumberger, 2014-2016).

Mine hobbier er sykling, langrenn, og fjellturer.

Publikasjoner

  • Parekh, Pravesh; Fan, Chun Chieh; Frei, Oleksandr; Palmer, Clare E.; Smith, Diana M. & Makowski, Carolina [Vis alle 17 forfattere av denne artikkelen] (2024). FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data. Human Brain Mapping. ISSN 1065-9471. 45(2). doi: 10.1002/hbm.26579.
  • Holen, Børge; Kutrolli, Gleda; Shadrin, Alexey; Icick, Romain; Hindley, Guy & Rødevand, Linn [Vis alle 16 forfattere av denne artikkelen] (2023). Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability. Drug and Alcohol Dependence. ISSN 0376-8716. 256. doi: 10.1016/j.drugalcdep.2023.111058. Fulltekst i vitenarkiv
  • Nordengen, Kaja; Cappelletti, Chiara; Bahrami, Shahram; Frei, Oleksandr; Pihlstrøm, Lasse & Henriksen, Sandra Pilar [Vis alle 11 forfattere av denne artikkelen] (2023). Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease. Brain. ISSN 0006-8950. s. 1–13. doi: 10.1093/brain/awad297. Fulltekst i vitenarkiv
  • Bøen, Rune; Kaufmann, Tobias Herbert; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid & Ames, David [Vis alle 53 forfattere av denne artikkelen] (2023). Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry. ISSN 0006-3223. 95(2), s. 147–160. doi: 10.1016/j.biopsych.2023.08.018. Fulltekst i vitenarkiv
  • Jaholkowski, Piotr Pawel; Hindley, Guy; Shadrin, Alexey; Tesfaye, Markos ; Bahrami, Shahram & Nerhus, Mari [Vis alle 19 forfattere av denne artikkelen] (2023). Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci. Schizophrenia Bulletin. ISSN 0586-7614. 49(6), s. 1654–1664. doi: 10.1093/schbul/sbad063. Fulltekst i vitenarkiv
  • Rødevand, Linn Nilsen; Rahman, Zillur; Hindley, Guy Frederick Lanyon; Smeland, Olav Bjerkehagen; Frei, Oleksandr & Filiz, Tahir Tekin [Vis alle 15 forfattere av denne artikkelen] (2023). Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors. American Journal of Psychiatry. ISSN 0002-953X. 180(11), s. 815–826. doi: 10.1176/APPI.AJP.20220660.
  • Steen, Nils Eiel; Rahman, Zillur; Szabo, Attila; Hindley, Guy; Parker, Nadine & Cheng, Weiqiu [Vis alle 20 forfattere av denne artikkelen] (2023). Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities. Schizophrenia Bulletin. ISSN 0586-7614. 49(5), s. 1345–1354. doi: 10.1093/schbul/sbad082. Fulltekst i vitenarkiv
  • Parker, Nadine; Cheng, Weiqiu; Hindley, Guy; Parekh, Pravesh; Shadrin, Alexey & Maximov, Ivan [Vis alle 12 forfattere av denne artikkelen] (2023). Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-023-02264-z.
  • Hindley, Guy; Drange, Ole Kristian; Lin, Aihua; Kutrolli, Gleda; Shadrin, Alexey & Parker, Nadine [Vis alle 20 forfattere av denne artikkelen] (2023). Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders. Psychoneuroendocrinology. ISSN 0306-4530. 157. doi: 10.1016/j.psyneuen.2023.106368. Fulltekst i vitenarkiv
  • Akdeniz, Bayram Cevdet ; Mattingsdal, Morten; Dominguez-Valentin, Mev; Frei, Oleksandr; Shadrin, Alexey & Puustusmaa, Mikk [Vis alle 12 forfattere av denne artikkelen] (2023). A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population. Cancers. ISSN 2072-6694. 15(16). doi: 10.3390/cancers15164124. Fulltekst i vitenarkiv
  • Woldeyohannes, Markos Tesfaye; Jaholkowski, Piotr Pawel; Hindley, Guy; Shadrin, Alexey; Rahman, Zillur & Bahrami, Shahram [Vis alle 17 forfattere av denne artikkelen] (2023). Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis. Genome Medicine. ISSN 1756-994X. 15(1). doi: 10.1186/s13073-023-01212-4. Fulltekst i vitenarkiv
  • Hope, Sigrun; Shadrin, Alexey; Lin, Aihua; Bahrami, Shahram; Rødevand, Linn & Frei, Oleksandr [Vis alle 17 forfattere av denne artikkelen] (2023). Bidirectional genetic overlap between autism spectrum disorder and cognitive traits. Translational Psychiatry. ISSN 2158-3188. 13(1), s. 1–9. doi: 10.1038/s41398-023-02563-7. Fulltekst i vitenarkiv
  • Bang, Lasse; Bahrami, Shahram; Hindley, Guy; Smeland, Olav Bjerkehagen; Rødevand, Linn & Jaholkowski, Piotr Pawel [Vis alle 18 forfattere av denne artikkelen] (2023). Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa. Translational Psychiatry. ISSN 2158-3188. 13. doi: 10.1038/s41398-023-02585-1. Fulltekst i vitenarkiv
  • Campbell, Megan L.; Dalvie, Shareefa; Shadrin, Alexey; van der Meer, Dennis; O'Connell, Kevin Sean & Frei, Oleksandr [Vis alle 9 forfattere av denne artikkelen] (2023). Distributed Genetic Effects of the Corpus Callosum Subregions Suggest Links to Neuropsychiatric Disorders and Related Traits. Acta Neuropsychiatrica. ISSN 0924-2708. doi: 10.1017/neu.2023.32. Fulltekst i vitenarkiv
  • Karadag, Naz; Shadrin, Alexey; O'Connell, Kevin Sean; Hindley, Guy Frederick Lanyon; Rahman, Zillur & Parker, Nadine [Vis alle 18 forfattere av denne artikkelen] (2023). Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders. Brain. ISSN 0006-8950. 146(8), s. 3392–3403. doi: 10.1093/brain/awad038. Fulltekst i vitenarkiv
  • Mufford, Mary S.; van der Meer, Dennis; Kaufmann, Tobias Herbert; Frei, Oleksandr; Ramesar, Raj & Thompson, Paul M. [Vis alle 11 forfattere av denne artikkelen] (2023). The Genetic Architecture of Amygdala Nuclei. Biological Psychiatry. ISSN 0006-3223. doi: 10.1016/j.biopsych.2023.06.022. Fulltekst i vitenarkiv
  • Parker, Nadine; Cheng, Weiqiu; Hindley, Guy; O'Connell, Kevin Sean; Karthikeyan, Sandeep & Holen, Børge [Vis alle 19 forfattere av denne artikkelen] (2023). Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts. Biological Psychiatry. ISSN 0006-3223. doi: 10.1016/j.biopsych.2023.06.008. Fulltekst i vitenarkiv
  • Roelfs, Daniel; Frei, Oleksandr; van der Meer, Dennis; Tissink, Elleke; Shadrin, Alexey & Alnæs, Dag [Vis alle 9 forfattere av denne artikkelen] (2023). Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank. BMC Psychiatry. ISSN 1471-244X. 23(1). doi: 10.1186/s12888-023-04905-7. Fulltekst i vitenarkiv
  • Hindley, Guy Frederick Lanyon; Shadrin, Alexey; van der Meer, Dennis; Parker, Nadine; Cheng, Weiqiu & O'Connell, Kevin Sean [Vis alle 23 forfattere av denne artikkelen] (2023). Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy. Nature Human Behaviour. ISSN 2397-3374. 7, s. 1584–1600. doi: 10.1038/s41562-023-01630-9.
  • Askeland, Ragna Bugge; Hannigan, Laurie John; O'Connell, Kevin Sean; Corfield, Elizabeth Claire; Frei, Oleksandr & Thapar, Anita [Vis alle 11 forfattere av denne artikkelen] (2023). Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood. Translational Psychiatry. ISSN 2158-3188. 13. doi: 10.1038/s41398-023-02522-2. Fulltekst i vitenarkiv
  • Makowski, Carolina; Wang, Hao; Srinivasan, Anjali; Qi, Anna; Qiu, Yuqi & van der Meer, Dennis [Vis alle 11 forfattere av denne artikkelen] (2023). Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 120(11). doi: 10.1073/pnas.2214834120. Fulltekst i vitenarkiv
  • Leonardsen, Esten Høyland; Vidal-Piñeiro, Didac; Roe, James Michael; Frei, Oleksandr; Shadrin, Alexey & Iakunchykova, Olena [Vis alle 14 forfattere av denne artikkelen] (2023). Genetic architecture of brain age and its casual relations with brain and mental disorders. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-023-02087-y. Fulltekst i vitenarkiv
  • Reas, Emilie T.; Shadrin, Alexey; Frei, Oleksandr; Motazedi, Ehsan; McEvoy, Linda & Bahrami, Shahram [Vis alle 22 forfattere av denne artikkelen] (2023). Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures. Alzheimer's & Dementia. ISSN 1552-5260. 19(11), s. 5151–5158. doi: 10.1002/alz.13112. Fulltekst i vitenarkiv
  • O'Connell, Kevin Sean; Koch, Elise; Lenk, Hasan Cagin; Akkouh, Ibrahim Ahmed; Hindley, Guy Frederick Lanyon & Jaholkowski, Piotr Pawel [Vis alle 16 forfattere av denne artikkelen] (2023). Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia. Psychiatry Research. ISSN 0165-1781. 325. doi: 10.1016/j.psychres.2023.115217. Fulltekst i vitenarkiv
  • Holen, Børge; Shadrin, Alexey; Icick, Romain; Filiz, Tahir Tekin; Hindley, Guy Frederick Lanyon & Rødevand, Linn [Vis alle 19 forfattere av denne artikkelen] (2023). Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression. Addiction Biology. ISSN 1355-6215. 28(6). doi: 10.1111/adb.13282. Fulltekst i vitenarkiv
  • Oddsson, Asmundur; Sulem, Patrick; Sveinbjornsson, Gardar; Arnadottir, Gudny A.; Steinthorsdottir, Valgerdur & Halldorsson, Gisli H. [Vis alle 54 forfattere av denne artikkelen] (2023). Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality. Nature Communications. ISSN 2041-1723. 14. doi: 10.1038/s41467-023-38951-2. Fulltekst i vitenarkiv
  • Fominykh, Vera; Shadrin, Alexey; Jaholkowski, Piotr Pawel; Bahrami, Shahram; Athanasiu, Lavinia & Wightman, Douglas P. [Vis alle 13 forfattere av denne artikkelen] (2023). Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system. Neurobiology of Disease. ISSN 0969-9961. 183. doi: 10.1016/j.nbd.2023.106174. Fulltekst i vitenarkiv
  • Cheng, Weiqiu; Parker, Nadine; Karadag, Naz; Koch, Elise; Hindley, Guy Frederick Lanyon & Icick, Romain [Vis alle 22 forfattere av denne artikkelen] (2023). The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study. The Lancet Psychiatry. ISSN 2215-0374. 10(6), s. 441–451. doi: 10.1016/S2215-0366(23)00143-8. Fulltekst i vitenarkiv
  • Smith, Diana M.; Loughnan, Robert; Friedman, Naomi P.; Parekh, Pravesh; Frei, Oleksandr & Thompson, Wesley K. [Vis alle 10 forfattere av denne artikkelen] (2023). Heritability Estimation of Cognitive Phenotypes in the ABCD Study<sup>®</sup> Using Mixed Models. Behavior Genetics. ISSN 0001-8244. 53(3), s. 169–188. doi: 10.1007/s10519-023-10141-2. Fulltekst i vitenarkiv
  • Jaholkowski, Piotr; Shadrin, Alexey A.; Jangmo, Andreas; Frei, Evgeniia; Woldeyohannes, Markos Tesfaye & Hindley, Guy F. L. [Vis alle 23 forfattere av denne artikkelen] (2023). Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders. JAMA psychiatry. ISSN 2168-6238. 80(7), s. 738–742. doi: 10.1001/jamapsychiatry.2023.1137.
  • Bøen, Rune; Kaufmann, Tobias; Frei, Oleksandr; van der Meer, Dennis; Djurovic, Srdjan & Andreassen, Ole [Vis alle 9 forfattere av denne artikkelen] (2023). No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank. Translational Psychiatry. ISSN 2158-3188. 13:61, s. 1–6. doi: 10.1038/s41398-023-02358-w. Fulltekst i vitenarkiv
  • Andreassen, Ole; Hindley, Guy Frederick Lanyon; Frei, Oleksandr & Smeland, Olav Bjerkehagen (2023). New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications. World Psychiatry. ISSN 1723-8617. 22(1), s. 4–24. doi: 10.1002/wps.21034.
  • Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik Slagvold; O`Connell, Kevin S.; Frei, Oleksandr & Shadrin, Alexey [Vis alle 16 forfattere av denne artikkelen] (2022). Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. Brain. ISSN 0006-8950. doi: 10.1093/brain/awab267.
  • Akdeniz, Bayram Cevdet ; Frei, Oleksandr; Shadrin, Alexey; Vetrov, Dmitry; Kropotov, Dmitry & Dale, Anders [Vis alle 8 forfattere av denne artikkelen] (2022). Finemap-MiXeR: A variational Bayesian approach for genetic finemapping. bioRxiv. ISSN 2692-8205.
  • Akdeniz, Bayram Cevdet ; Frei, Oleksandr; Hagen, Espen; Filiz, Tahir Tekin; Karthikeyan, Sandeep & Pasman, Joëlle [Vis alle 18 forfattere av denne artikkelen] (2022). COGEDAP: A COmprehensive GEnomic Data Analysis Platform. arXiv.org. ISSN 2331-8422.
  • van der Meer, Dennis; Gurholt, Tiril Pedersen; Sønderby, Ida Elken; Shadrin, Alexey; Hindley, Guy Frederick Lanyon & Rahman, Zillur [Vis alle 18 forfattere av denne artikkelen] (2022). The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition. Communications Biology. ISSN 2399-3642. 5(1). doi: 10.1038/s42003-022-04237-4. Fulltekst i vitenarkiv
  • Loughnan, Robert J.; Shadrin, Alexey; Frei, Oleksandr; van der Meer, Dennis; Zhao, Weiqi & Palmer, Clare E. [Vis alle 12 forfattere av denne artikkelen] (2022). Generalization of cortical MOSTest genome-wide associations within and across samples. NeuroImage. ISSN 1053-8119. 263. doi: 10.1016/j.neuroimage.2022.119632. Fulltekst i vitenarkiv
  • Fan, Chun Chieh; Loughnan, Robert; Makowski, Carolina; Pecheva, Diliana; Chen, Chi-Hua & Hagler, Donald J. [Vis alle 12 forfattere av denne artikkelen] (2022). Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain. Nature Communications. ISSN 2041-1723. 13(1). doi: 10.1038/s41467-022-30110-3. Fulltekst i vitenarkiv
  • Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean; Rahman, Zillur; Frei, Oleksandr; Bahrami, Shahram & Shadrin, Alexey [Vis alle 17 forfattere av denne artikkelen] (2022). The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. ISSN 1552-4841. 189(6), s. 207–218. doi: 10.1002/ajmg.b.32907. Fulltekst i vitenarkiv
  • Cheng, Weiqiu; van der Meer, Dennis; Parker, Nadine; Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean & Wang, Yunpeng [Vis alle 20 forfattere av denne artikkelen] (2022). Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-022-01751-z. Fulltekst i vitenarkiv
  • Bahrami, Shahram; Nordengen, Kaja; Shadrin, Alexey; Frei, Oleksandr; van der Meer, Dennis & Dale, Anders [Vis alle 9 forfattere av denne artikkelen] (2022). Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders. Nature Communications. ISSN 2041-1723. 13(1). doi: 10.1038/s41467-022-31086-w. Fulltekst i vitenarkiv
  • Torgersen, Kristin Stensland; Rahman, Zillur; Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Parker, Nadine & Frei, Oleksandr [Vis alle 14 forfattere av denne artikkelen] (2022). Shared genetic loci between depression and cardiometabolic traits. PLoS Genetics. ISSN 1553-7390. 18(5). doi: 10.1371/journal.pgen.1010161. Fulltekst i vitenarkiv
  • Hindley, Guy; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; O'Connell, Kevin Sean & Icick, Romain [Vis alle 17 forfattere av denne artikkelen] (2022). Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation. American Journal of Psychiatry. ISSN 0002-953X. 179(11), s. 833–843. doi: 10.1176/appi.ajp.21101051.
  • Icick, Romain; Shadrin, Alexey; Holen, Børge; Karadag, Naz; Lin, Aihua & Hindley, Guy [Vis alle 17 forfattere av denne artikkelen] (2022). Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings. Neuropsychopharmacology. ISSN 0893-133X. 47, s. 1883–1891. doi: 10.1038/s41386-022-01401-6.
  • Saevarsdottir, Saedis; Stefansdottir, Lilja; Sulem, Patrick; Thorleifsson, Gudmar; Ferkingstad, Egil & Rutsdottir, Gudrun [Vis alle 78 forfattere av denne artikkelen] (2022). Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset. Annals of the Rheumatic Diseases. ISSN 0003-4967. 81(8), s. 1085–1095. doi: 10.1136/annrheumdis-2021-221754. Fulltekst i vitenarkiv
  • Motazedi, Ehsan; Cheng, Weiqiu; Thomassen, Jesper Qvist; Frei, Oleksandr; Rongve, Arvid & Athanasiu, Lavinia [Vis alle 30 forfattere av denne artikkelen] (2022). Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations. Journal of Alzheimer's Disease. ISSN 1387-2877. 88(4), s. 1533–1544. doi: 10.3233/JAD-220174.
  • van der Meer, Dennis; Shadrin, Alexey; O'Connell, Kevin Sean; Bettella, Francesco; Djurovic, Srdjan & Wolfers, Thomas [Vis alle 17 forfattere av denne artikkelen] (2022). Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology. Biological Psychiatry. ISSN 0006-3223. 92(4), s. 291–298. doi: 10.1016/j.biopsych.2021.12.007. Fulltekst i vitenarkiv
  • Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin Sean; Frei, Oleksandr & Shadrin, Alexey [Vis alle 39 forfattere av denne artikkelen] (2022). Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. Brain. ISSN 0006-8950. 145(1), s. 142–153. doi: 10.1093/brain/awab267. Fulltekst i vitenarkiv
  • Hindley, Guy Frederick Lanyon; Bahrami, Shahram; Steen, Nils Eiel; O’Connell, Kevin S.; Frei, Oleksandr & Shadrin, Alexey [Vis alle 13 forfattere av denne artikkelen] (2021). Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-021-01576-4.
  • Mullins, Niamh; Forstner, Andreas J.; O'Connell, Kevin Sean; Coombes, Brandon; Coleman, Jonathan R. I. & Qiao, Zhen [Vis alle 59 forfattere av denne artikkelen] (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. ISSN 1061-4036. 53, s. 817–829. doi: 10.1038/s41588-021-00857-4.
  • van der Meer, Dennis; Kaufmann, Tobias; Shadrin, Alexey; Makowski, Carolina; Frei, Oleksandr & Roelfs, Daniel [Vis alle 17 forfattere av denne artikkelen] (2021). The genetic architecture of human cortical folding. Science Advances. ISSN 2375-2548. 7(51), s. 1–9. doi: 10.1126/sciadv.abj9446. Fulltekst i vitenarkiv
  • Shadrin, Alexey A.; Kaufmann, Tobias; van der Meer, Dennis; Palmer, Clare E.; Makowski, Carolina & Loughnan, Robert [Vis alle 22 forfattere av denne artikkelen] (2021). Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology. NeuroImage. ISSN 1053-8119. 244, s. 1–8. doi: 10.1016/j.neuroimage.2021.118603. Fulltekst i vitenarkiv
  • Pihlstrøm, Lasse; Fan, Chun Chieh; Frei, Oleksandr; Tan, Manuela; Karunamuni, Roshan A. & Blauwendraat, Cornelis [Vis alle 12 forfattere av denne artikkelen] (2021). Genetic Stratification of Age-Dependent Parkinson's Disease Risk by Polygenic Hazard Score. Movement Disorders. ISSN 0885-3185. doi: 10.1002/mds.28808. Fulltekst i vitenarkiv
  • Wiström, Erik David; O'Connell, Kevin Sean; Karadag, Naz; Bahrami, Shahram; Hindley, Guy Frederick Lanyon & Lin, Aihua [Vis alle 14 forfattere av denne artikkelen] (2021). Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci. Addiction. ISSN 0965-2140. doi: 10.1111/add.15680. Fulltekst i vitenarkiv
  • Monereo-Sánchez, Jennifer; Schram, Miranda T.; Frei, Oleksandr; O'Connell, Kevin Sean; Shadrin, Alexey & Smeland, Olav Bjerkehagen [Vis alle 11 forfattere av denne artikkelen] (2021). Genetic Overlap Between Alzheimer’s Disease and Depression Mapped Onto the Brain. Frontiers in Neuroscience. ISSN 1662-4548. 15, s. 1–9. doi: 10.3389/fnins.2021.653130. Fulltekst i vitenarkiv
  • O'Connell, Kevin Sean; Frei, Oleksandr; Bahrami, Shahram; Smeland, Olav Bjerkehagen; Bettella, Francesco & Cheng, Weiqiu [Vis alle 16 forfattere av denne artikkelen] (2021). Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes. Biological Psychiatry. ISSN 0006-3223. s. 1–11. doi: 10.1016/j.biopsych.2021.07.007. Fulltekst i vitenarkiv
  • Hindley, Guy Frederick Lanyon; Bahrami, Shahram; Steen, Nils Eiel; O'Connell, Kevin Sean; Frei, Oleksandr & Shadrin, Alexey [Vis alle 13 forfattere av denne artikkelen] (2021). Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking. Translational Psychiatry. ISSN 2158-3188. 11:466, s. 1–10. doi: 10.1038/s41398-021-01576-4. Fulltekst i vitenarkiv
  • Elvsåshagen, Torbjørn; Shadrin, Alexey; Frei, Oleksandr; van der Meer, Dennis; Bahrami, Shahram & Kumar, Vinod J. [Vis alle 10 forfattere av denne artikkelen] (2021). The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Nature Communications. ISSN 2041-1723. 12(1). doi: 10.1038/s41467-021-23175-z. Fulltekst i vitenarkiv
  • Holland, Dominic; Frei, Oleksandr; Desikan, Rahul S.; Fan, Chun Chieh; Shadrin, Alexey & Smeland, Olav Bjerkehagen [Vis alle 8 forfattere av denne artikkelen] (2021). The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity. Genetics. ISSN 0016-6731. 217(3), s. 1–21. doi: 10.1093/genetics/iyaa046.
  • Torgersen, Kristin Stensland; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin Sean & Smeland, Olav Bjerkehagen [Vis alle 10 forfattere av denne artikkelen] (2021). Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors. Translational Psychiatry. ISSN 2158-3188. 11(1), s. 1–13. doi: 10.1038/s41398-021-01466-9. Fulltekst i vitenarkiv
  • Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi & Ellegaard, Maria [Vis alle 76 forfattere av denne artikkelen] (2021). 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry. ISSN 2158-3188. 11. doi: 10.1038/s41398-021-01213-0. Fulltekst i vitenarkiv
  • O'Connell, Kevin S.; Sønderby, Ida Elken; Frei, Oleksandr; van der Meer, Dennis; Athanasiu, Lavinia & Smeland, Olav Bjerkehagen [Vis alle 13 forfattere av denne artikkelen] (2021). Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine. ISSN 0033-2917. s. 1–11. doi: 10.1017/S0033291721000179. Fulltekst i vitenarkiv
  • Rødevand, Linn ; Bahrami, Shahram; Frei, Oleksandr; Chu, Yunhan; Shadrin, Alexey A. & O'Connell, Kevin Sean [Vis alle 14 forfattere av denne artikkelen] (2021). Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes. Translational Psychiatry. ISSN 2158-3188. 11. doi: 10.1038/s41398-021-01527-z. Fulltekst i vitenarkiv
  • Cheng, Weiqiu; Frei, Oleksandr; van der Meer, Dennis; Wang, Yunpeng; O`Connell, Kevin & Chu, Yunhan [Vis alle 20 forfattere av denne artikkelen] (2021). Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness. JAMA psychiatry. ISSN 2168-6238. 78(9), s. 1020–1030. doi: 10.1001/jamapsychiatry.2021.1435. Fulltekst i vitenarkiv
  • Gurholt, Tiril Pedersen; Kaufmann, Tobias; Frei, Oleksandr; Alnæs, Dag; Haukvik, Unn Kristin H. & van der Meer, Dennis [Vis alle 17 forfattere av denne artikkelen] (2021). Population-based body–brain mapping links brain morphology with anthropometrics and body composition. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-021-01414-7. Fulltekst i vitenarkiv
  • Maximov, Ivan; van der Meer, Dennis; de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Shadrin, Alexey A. & Frei, Oleksandr [Vis alle 8 forfattere av denne artikkelen] (2021). Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: U.K. Biobank 18,608 example. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25424. Fulltekst i vitenarkiv
  • Bahrami, Shahram; Shadrin, Alexey A.; Frei, Oleksandr; O`Connell, Kevin; Bettella, Francesco & Krull, Florian [Vis alle 15 forfattere av denne artikkelen] (2021). Genetic loci shared between major depression and intelligence with mixed directions of effect. Nature Human Behaviour. ISSN 2397-3374. s. 1–9. doi: 10.1038/s41562-020-01031-2.
  • Roelfs, Daniel; Alnæs, Dag; Frei, Oleksandr; van der Meer, Dennis; Smeland, Olav Bjerkehagen & Andreassen, Ole Andreas [Vis alle 8 forfattere av denne artikkelen] (2021). Phenotypically independent profiles relevant to mental health are genetically correlated. Translational Psychiatry. ISSN 2158-3188. 11(1). doi: 10.1038/s41398-021-01313-x. Fulltekst i vitenarkiv
  • Rødevand, Linn ; Bahrami, Shahram; Frei, Oleksandr; Lin, Aihua; Gani, Osman & Shadrin, Alexey A. [Vis alle 18 forfattere av denne artikkelen] (2021). Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms. Translational Psychiatry. ISSN 2158-3188. 11(1). doi: 10.1038/s41398-020-01142-4. Fulltekst i vitenarkiv
  • Holland, Dominic; Frei, Oleksandr; Desikan, Rahul S.; Fan, Chun-Chieh; Shadrin, Alexey A. & Smeland, Olav Bjerkehagen [Vis alle 10 forfattere av denne artikkelen] (2020). Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model. PLoS Genetics. ISSN 1553-7390. doi: 10.1371/journal.pgen.1008612. Fulltekst i vitenarkiv
  • Shadrin, Alexey A.; Mucha, Sören; Ellinghaus, David; Makarious, Mary B; Blauwendraat, Cornelis & Sreelatha, Ashwin [Vis alle 36 forfattere av denne artikkelen] (2020). Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease. Movement Disorders. ISSN 0885-3185. doi: 10.1002/mds.28338. Fulltekst i vitenarkiv
  • Shadrin, Alexey A.; Frei, Oleksandr; Smeland, Olav Bjerkehagen; Bettella, Francesco; O`Connell, Kevin & Gani, Osman [Vis alle 12 forfattere av denne artikkelen] (2020). Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR. Bioinformatics. ISSN 1367-4803. doi: 10.1093/bioinformatics/btaa568. Fulltekst i vitenarkiv
  • Elvsåshagen, Torbjørn; Bahrami, Shahram; van der Meer, Dennis; Agartz, Ingrid; Alnæs, Dag & Barch, Deanna M. [Vis alle 76 forfattere av denne artikkelen] (2020). The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nature Communications. ISSN 2041-1723. 11. doi: 10.1038/s41467-020-17376-1. Fulltekst i vitenarkiv
  • Còrdova Palomera, Aldo; van der Meer, Dennis; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng & Alnæs, Dag [Vis alle 40 forfattere av denne artikkelen] (2020). Genetic control of variability in subcortical and intracranial volumes. Molecular Psychiatry. ISSN 1359-4184. s. 1–8. doi: 10.1038/s41380-020-0664-1. Fulltekst i vitenarkiv
  • van der Meer, Dennis; Frei, Oleksandr; Kaufmann, Tobias; Shadrin, Alexey A.; Devor, Anna & Smeland, Olav Bjerkehagen [Vis alle 12 forfattere av denne artikkelen] (2020). Understanding the genetic determinants of the brain with MOSTest. Nature Communications. ISSN 2041-1723. 11:3512, s. 1–9. doi: 10.1038/s41467-020-17368-1.
  • Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Bahrami, Shahram; Broce, Iris J.; Tesli, Martin Steen & Frei, Oleksandr [Vis alle 22 forfattere av denne artikkelen] (2020). Genome-wide Association Analysis of Parkinson’s Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci. Biological Psychiatry. ISSN 0006-3223. 89(3), s. 227–235. doi: 10.1016/j.biopsych.2020.01.026. Fulltekst i vitenarkiv
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Dale, Anders & Andreassen, Ole Andreas (2020). The polygenic architecture of schizophrenia — rethinking pathogenesis and nosology. Nature Reviews Neurology. ISSN 1759-4758. s. 1–14. doi: 10.1038/s41582-020-0364-0.
  • Bahrami, Shahram; Steen, Nils Eiel; Shadrin, Alexey A.; O`Connell, Kevin; Frei, Oleksandr & Bettella, Francesco [Vis alle 13 forfattere av denne artikkelen] (2020). Shared genetic loci between body mass index and major psychiatric disorders: A genome-wide association study. JAMA psychiatry. ISSN 2168-6238. 77(5), s. 503–512. doi: 10.1001/jamapsychiatry.2019.4188.
  • van der Meer, Dennis; Frei, Oleksandr; Kaufmann, Tobias; Chen, Chi-Hua; Thompson, Wesley K. & O'Connell, Kevin S. [Vis alle 11 forfattere av denne artikkelen] (2020). Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area. Cerebral Cortex. ISSN 1047-3211. 30(10), s. 5597–5603. doi: 10.1093/cercor/bhaa146. Fulltekst i vitenarkiv
  • Lam, Max; Awasthi, Swapnil; Watson, Hunna J.; Goldstein, Jackie; Panagiotaropoulou, Georgia & Trubetskoy, Vassily [Vis alle 22 forfattere av denne artikkelen] (2019). RICOPILI: Rapid Imputation for COnsortias PIpeLIne. Bioinformatics. ISSN 1367-4803. 36(3), s. 930–933. doi: 10.1093/bioinformatics/btz633. Fulltekst i vitenarkiv
  • O`Connell, Kevin; Shadrin, Alexey A.; Smeland, Olav Bjerkehagen; Bahrami, Shahram; Frei, Oleksandr & Bettella, Francesco [Vis alle 24 forfattere av denne artikkelen] (2019). Identification of genetic loci shared between ADHD, intelligence and educational attainment . Biological Psychiatry. ISSN 0006-3223. 87(12), s. 1052–1062. doi: 10.1016/j.biopsych.2019.11.015. Fulltekst i vitenarkiv
  • Watanabe, Kyoko; Stringer, Sven; Frei, Oleksandr; Mirkov, Maša Umićević; de Leeuw, Christiaan & Polderman, Tinca J.C. [Vis alle 10 forfattere av denne artikkelen] (2019). A global overview of pleiotropy and genetic architecture in complex traits. Nature Genetics. ISSN 1061-4036. 51(9), s. 1339–1348. doi: 10.1038/s41588-019-0481-0.
  • O`Connell, Kevin; Shadrin, Alexey A.; Bahrami, Shahram; Smeland, Olav Bjerkehagen; Bettella, Francesco & Frei, Oleksandr [Vis alle 20 forfattere av denne artikkelen] (2019). Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder. Molecular Psychiatry. ISSN 1359-4184. s. 1–11. doi: 10.1038/s41380-019-0613-z. Fulltekst i vitenarkiv
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Shadrin, Alexey A.; O`Connell, Kevin; Fan, Chun Chieh & Bahrami, Shahram [Vis alle 11 forfattere av denne artikkelen] (2019). Discovery of shared genomic loci using the conditional false discovery rate approach. Human Genetics. ISSN 0340-6717. s. 1–10. doi: 10.1007/s00439-019-02060-2. Fulltekst i vitenarkiv
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Fan, Chun-Chieh; Shadrin, Alexey A.; Dale, Anders & Andreassen, Ole Andreas (2019). The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges. Psychiatric Genetics. ISSN 0955-8829. 29(5), s. 152–159. doi: 10.1097/YPG.0000000000000234. Fulltekst i vitenarkiv
  • Frei, Oleksandr; Holland, Dominic; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Fan, Chun Chieh & Mæland, Steffen [Vis alle 12 forfattere av denne artikkelen] (2019). Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation. Nature Communications. ISSN 2041-1723. 10(1). doi: 10.1038/s41467-019-10310-0. Fulltekst i vitenarkiv
  • Drange, Ole Kristian; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Finseth, Per Ivar; Witoelar, Aree & Frei, Oleksandr [Vis alle 52 forfattere av denne artikkelen] (2019). Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes. Frontiers in Neuroscience. ISSN 1662-4548. 13. doi: 10.3389/fnins.2019.00220. Fulltekst i vitenarkiv

Se alle arbeider i Cristin

  • Hindley, Guy; Drange, Ole Kristian; Lin, Aihua; Kutrolli, Gleda; Shadrin, Alexey & Parker, Nadine [Vis alle 20 forfattere av denne artikkelen] (2024). Corrigendum to “Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders” [Psychoneuroendocrinology 157 (2023) 106368] (Psychoneuroendocrinology (2023) 157, (S0306453023003463), (10.1016/j.psyneuen.2023.106368)). Psychoneuroendocrinology. ISSN 0306-4530. doi: 10.1016/j.psyneuen.2024.106980.
  • Shorter, John; Pasman, Joëlle; Jangmo, Andreas; Kurvits, Siim; Meijsen, Joeri & Frei, Oleksandr [Vis alle 15 forfattere av denne artikkelen] (2022). A LARGE META-ANALYSIS ACROSS FOUR NORDIC COUNTRIES REVEALS SEVERAL SIGNIFICANT GENETIC ASSOCIATIONS FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER. European Neuropsychopharmacology. ISSN 0924-977X.
  • Pasman, Joëlle; Shorter, John; Jangmo, Andreas; Kurvits, Siim; Meijsen, Joeri & Frei, Oleksandr [Vis alle 13 forfattere av denne artikkelen] (2022). IS GENETIC RISK FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER ASSOCIATED WITH MORE SEVERE CLINICAL FEATURES THAN BROAD MAJOR DEPRESSIVE DISORDER? European Neuropsychopharmacology. ISSN 0924-977X.
  • Akdeniz, Bayram Cevdet ; Bøen, Rune; Frei, Oleksandr; Hovig, Eivind; Andreassen, Ole & Sønderby, Ida Elken (2022). LARGE-SCALE ANALYSIS WITH SOFTWARE CONTAINERS IN ENIGMA-CNV–AN INTERNATIONAL WORKING GROUP TO STUDY RECURRENT COPY NUMBER VARIANTS AND BRAIN MEASURES. Neuropsychopharmacology, 2022.
  • Akdeniz, Bayram Cevdet ; Mattingsdal, Morten; Dominguez Valentin, Mev; Frei, Oleksandr; Shadrin, Alexey & Puustusmaa, Mikk [Vis alle 11 forfattere av denne artikkelen] (2022). Implementation of polygenic risk score guided breast cancer prediction in Norwegian data. NSHG-PM 2022.
  • Corfield, Elizabeth Claire; Shadrin, Alexey; Frei, Oleksandr; Rahman, Zillur; Lin, Aihua & Athanasiu, Lavinia [Vis alle 15 forfattere av denne artikkelen] (2022). Genetic profile of the Norwegian Mother, Father, and Child Cohort Study (MoBa): Results from the MoBaPsychGen pipeline.
  • Corfield, Elizabeth Claire; Frei, Oleksandr; Shadrin, Alexey; Rahman, Zillur; Lin, Aihua & Athanasiu, Lavinia [Vis alle 26 forfattere av denne artikkelen] (2022). The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: the MoBaPsychGen_v1 pipeline.
  • Askeland, Ragna Bugge; Hannigan, Laurie John; O'Connell, Kevin Sean; Corfield, Elizabeth Claire; Frei, Oleksandr & Thapar, Anita [Vis alle 11 forfattere av denne artikkelen] (2022). Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood.
  • Maximov, Ivan; van der Meer, Dennis; de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Shadrin, Alexey & Frei, Oleksandr [Vis alle 8 forfattere av denne artikkelen] (2021). YTTRIUM: QC algorithm for the processed diffusion maps in UK Biobank 18608 sample.
  • van der Meer, Dennis; Frei, Oleksandr; Kaufmann, Tobias; Shadrin, Alexey; Devor, Anna & Smeland, Olav Bjerkehagen [Vis alle 12 forfattere av denne artikkelen] (2020). Author Correction: Understanding the genetic determinants of the brain with MOSTest (Nature Communications, (2020), 11, 1, (3512), 10.1038/s41467-020-17368-1). Nature Communications. ISSN 2041-1723. 11(1). doi: 10.1038/s41467-020-18628-w.
  • Watanabe, Kyoko; Stringer, Sven; Frei, Oleksandr; Mirkov, Maša Umićević; de Leeuw, Christiaan & Polderman, Tinca J. C. [Vis alle 10 forfattere av denne artikkelen] (2020). Author Correction: A global overview of pleiotropy and genetic architecture in complex traits (Nature Genetics, (2019), 51, 9, (1339-1348), 10.1038/s41588-019-0481-0). Nature Genetics. ISSN 1061-4036. 52(3). doi: 10.1038/s41588-019-0571-z.
  • Smeland, Olav Bjerkehagen; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin & Savage, Jeanne [Vis alle 15 forfattere av denne artikkelen] (2019). Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence (Molecular Psychiatry, (2020), 25, 4, (844-853), 10.1038/s41380-018-0332-x). Molecular Psychiatry. ISSN 1359-4184. 25(4), s. 914–914. doi: 10.1038/s41380-019-0456-7.
  • Corfield, Elizabeth Claire; Frei, Oleksandr; Shadrin, Alexey; Rahman, Zillur; Lin, Aihua & Athanasiu, Lavinia [Vis alle 26 forfattere av denne artikkelen] (2022). The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1. Cold Spring Harbor Laboratory Press (CSHL). ISSN 2692-8205. (2022).

Se alle arbeider i Cristin

Publisert 7. juni 2016 08:53 - Sist endret 6. des. 2019 12:29

Prosjekter

Forskergrupper