Péter Fedorcsák

Professor II - Obstetrikk og gynekologi
Bilde av Péter Fedorcsák
English version of this page
Telefon +47-23070219
Mobiltelefon +47-48209435
Rom E2.3106
Brukernavn
Besøksadresse Sognsvannsveien 20 0372 Oslo
Postadresse Postboks 4956 Nydalen 0424 OSLO

Faglige interesser

Jeg er professor ved Universitetet i Oslo og avdelingsleder ved Reproduksjonsmedisinsk avdeling, Oslo universitetssykehus.

Min forskning dreier seg om:

  • reproduktiv aldring
  • systembiologisk undersøkelse av endometriosis
  • immunologisk regulering av fertilitet og ovariefunksjon
  • meiotiske celledeling og mannlig infertilitet

Bakgrunn

  • fra 2016 - Professor II
  • 2015 - 2016 Førsteamanuensis II
  • fra 2010 - Leder, Forskningsgruppen for reproduksjonsmedisin
  • 2004 - Dr.philos., Universitetet i Oslo
  • 1998 - Cand.med., Semmelweis universitetet i Budapest

Undervisning

Jeg underviser i obstetrikk og gynekologi (reproduksjonsmedisin) på grunnstudiet i medisin.

 

Emneord: Cellebiologi, Mor og barn, Flow cytometry, forskning

Publikasjoner

  • Jørgensen, Hilde; Hill, Abby S.; Beste, Michael T.; Kumar, Manu P.; Chiswick, Evan; Fedorcsák, Péter; Isaacson, Keith B.; Lauffenburger, Douglas A.; Griffith, Linda G. & Qvigstad, Erik (2017). Peritoneal fluid cytokines related to endometriosis in patients evaluated for infertility. Fertility and Sterility.  ISSN 0015-0282.  107(5), s 1191- 1199.e2 . doi: 10.1016/j.fertnstert.2017.03.013
  • Dahl, John Arne; Jung, Inkyung; Aanes, Håvard; Greggains, Gareth; Manaf, Adeel; Lerdrup, Mads; Li, Guoqiang; Kuan, Samantha; Li, Bin; Lee, Ah Young; Preissl, Sebastian; Jermstad, Ingunn; Haugen, Mads Haugland; Suganthan, Rajikala; Bjørås, Magnar; Hansen, Klaus; Dalen, Knut Tomas; Fedorcsák, Péter; Ren, Bing & Klungland, Arne (2016). Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. Nature.  ISSN 0028-0836.  537(7621), s 548- 552 . doi: 10.1038/nature19360
  • Klungland, Arne; Dahl, John Arne; Greggains, Gareth; Fedorcsák, Péter & Filipczyk, Adam (2016). Reversible RNA modifications in meiosis and pluripotency. Nature Methods.  ISSN 1548-7091.  14(1), s 18- 22 . doi: 10.1038/nmeth.4111
  • Landfors, Miriam; Nakken, Sigve; Fusser, Markus; Dahl, John Arne; Klungland, Arne & Fedorcsák, Péter (2016). Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations. Fertility and Sterility.  ISSN 0015-0282.  105(5), s 1170- 1179e5 . doi: 10.1016/j.fertnstert.2016.01.002
  • Tanbo, Tom Gunnar & Fedorcsák, Péter (2016). Endometriosis-associated infertility: aspects of pathophysiological mechanisms and treatment options. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349. . doi: 10.1111/aogs.13082
  • Stensen, Mette Haug; Tanbo, Tom Gunnar; Storeng, Eleftheria (Ritsa) T.; Åbyholm, Thomas & Fedorcsak, Peter (2015). Fragmentation of human cleavage-stage embryos is related to the progression through meiotic and mitotic cell cycles. Fertility and Sterility.  ISSN 0015-0282.  103(2), s 374- 381.e4 . doi: 10.1016/j.fertnstert.2014.10.031
  • Tanbo, Tom Gunnar; Greggains, Gareth; Storeng, Eleftheria (Ritsa) T.; Busund, Bjørn; Langebrekke, Anton & Fedorcsák, Péter (2015). Autotransplantation of cryopreserved ovarian tissue after treatment for malignant disease - The first Norwegian results. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  94(9), s 937- 941 . doi: 10.1111/aogs.12700
  • Haavaldsen, Camilla; Fedorcsak, Peter; Tanbo, Tom Gunnar & Eskild, Anne (2014). Maternal age and serum concentration of human chorionic gonadotropin in early pregnancy. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  93(12), s 1290- 1294 . doi: 10.1111/aogs.12471
  • Nilsen, Anja; Fusser, Markus; Greggains, Gareth; Fedorcsak, Peter & Klungland, Arne (2014). ALKBH4 depletion in mice leads to spermatogenic defects. PLoS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0105113
  • Polec, Anna; Fedorcsak, Peter; Eskild, Anne & Tanbo, Tom Gunnar (2014). The interplay of human chorionic gonadotropin (hCG) with basic fibroblast growth factor and adipokines on angiogenesis in vitro. Placenta.  ISSN 0143-4004.  35(4), s 249- 253 . doi: 10.1016/j.placenta.2014.02.002
  • Stensen, Mette Haug; Tanbo, Tom Gunnar; Storeng, Eleftheria (Ritsa) T. & Fedorcsak, Peter (2014). Advanced glycation end products and their receptor contribute to ovarian ageing. Human Reproduction.  ISSN 0268-1161.  29(1), s 125- 134 . doi: 10.1093/humrep/det419
  • Wilkosz, Pawel; Greggains, Gareth; Tanbo, Tom Gunnar & Fedorcsak, Peter (2014). Female reproductive decline is determined by remaining ovarian reserve and age. PLoS ONE.  ISSN 1932-6203.  9(10) . doi: 10.1371/journal.pone.0108343
  • Opøien, Hans Kristian; Fedorcsak, Peter; Polec, Anna; Stensen, Mette Haug; Åbyholm, Thomas & Tanbo, Tom Gunnar (2013). Do endometriomas induce an inflammatory reaction in nearby follicles?. Human Reproduction.  ISSN 0268-1161.  28(7), s 1837- 1845 . doi: 10.1093/humrep/det087
  • Zheng, Guanqun; Dahl, John Arne; Niu, Yamei; Fedorcsak, Peter; Huang, Chun-Min; Li, Charles J.; Vågbø, Cathrine Broberg; Shi, Yue; Wang, Wen-Ling; Song, Shu-Hui; Lu, Zhike; Bosmans, Ralph P. G.; Dai, Qing; Hao, Ya-Juan; Yang, Xin; Zhao, Wen-Ming; Tong, Wei-Min; Wang, Xiu-Jie; Bogdan, Florian; Furu, Kari; Fu, Ye; Jia, Guifang; Zhao, Xu; Liu, Jun; Krokan, Hans Einar; Klungland, Arne; Yang, Yun-Gui & He, Chuan (2013). ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility. Molecular Cell.  ISSN 1097-2765.  49(1), s 18- 29 . doi: 10.1016/j.molcel.2012.10.015
  • Eskild, Anne; Fedorcsak, Peter; Mørkrid, Lars & Tanbo, Tom Gunnar (2012). Maternal body mass index and serum concentrations of human chorionic gonadotropin in very early pregnancy. Fertility and Sterility.  ISSN 0015-0282.  98(4), s 905- 910 . doi: 10.1016/j.fertnstert.2012.06.011
  • Opøien, Hans Kristian; Fedorcsak, Peter; Omland, Anne Katerine; Åbyholm, Thomas; Bjercke, Sverre; Ertzeid, Gudvor; Oldereid, Nan Birgitte; Mellembakken, Jan Roar & Tanbo, Tom Gunnar (2012). In vitro fertilization is a successful treatment in endometriosis-associated infertility. Fertility and Sterility.  ISSN 0015-0282.  97(4), s 912- 918 . doi: 10.1016/j.fertnstert.2012.01.112
  • Mellembakken, Jan Roar; Berga, Sarah L.; Kilen, Mirjam; Tanbo, Tom Gunnar; Åbyholm, Thomas & Fedorcsak, Peter (2011). Sustained fertility from 22 to 41 years of age in women with polycystic ovarian syndrome. Human Reproduction.  ISSN 0268-1161.  26(9), s 2499- 2504 . doi: 10.1093/humrep/der214
  • Opøien, Hans Kristian; Fedorcsak, Peter; Åbyholm, Thomas & Tanbo, Tom Gunnar (2011). Complete surgical removal of minimal and mild endometriosis improves outcome of subsequent IVF/ICSI treatment. Reproductive Biomedicine Online.  ISSN 1472-6483.  23(3), s 389- 395 . doi: 10.1016/j.rbmo.2011.06.002
  • Polec, Anna; Raki, Melinda; Åbyholm, Thomas; Tanbo, Tom Gunnar & Fedorcsak, Peter (2011). Interaction between granulosa-lutein cells and monocytes regulates secretion of angiogenic factors in vitro. Human Reproduction.  ISSN 0268-1161.  26(10), s 2819- 2829 . doi: 10.1093/humrep/der216
  • Bjercke, Sverre; Tanbo, Tom Gunnar; Åbyholm, Thomas; Omland, Anne Katerine; Opøien, Hans Kristian & Fedorcsak, Peter (2010). Clinical outcome following stimulation with highly purified hMG or recombinant FSH in patients undergoing their first treatment cycle of IVF or ICSI. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  89(8), s 1053- 1060 . doi: 10.3109/00016349.2010.499450
  • Fedorcsak, Peter; Polec, Anna; Raki, Melinda; Holm, Ruth; Jebsen, Peter Wilhelm & Åbyholm, Thomas (2010). Differential Release of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases by Human Granulosa-Lutein Cells and Ovarian Leukocytes. Endocrinology.  ISSN 0013-7227.  151(3), s 1290- 1298 . doi: 10.1210/en.2009-0605
  • Stensen, Mette Haug; Tanbo, Tom Gunnar; Storeng, Eleftheria (Ritsa) T.; Åbyholm, Thomas & Fedorcsak, Peter (2010). Routine morphological scoring systems in assisted reproduction treatment fail to reflect age-related impairment of oocyte and embryo quality. Reproductive Biomedicine Online.  ISSN 1472-6483.  21(1), s 118- 125 . doi: 10.1016/j.rbmo.2010.03.018
  • Polec, Anna; Tanbo, Tom Gunnar & Fedorcsak, Peter (2009). Cellular Interaction Regulates Interleukin-8 Secretion by Granulosa-Lutein Cells and Monocytes/Macrophages. American Journal of Reproductive Immunology.  ISSN 8755-8920.  61(1), s 85- 94 . doi: 10.1111/j.1600-0897.2008.00668.x
  • Ertzeid, Gudvor; Fedorcsak, Peter; Åbyholm, Thomas & Tanbo, Tom Gunnar (2006). Elective single embryo transfer in assisted reproduction. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  126(23), s 3101- 3102
  • Omland, Anne Katerine; Bjercke, Sverre; Ertzeid, Gudvor; Fedorcsak, Peter; Oldereid, Nan Birgitte; Storeng, Ritsa; Åbyholm, Thomas & Tanbo, Tom Gunnar (2006). Intracytoplasmic sperm injection (ICSI) in unexplained and stage I endometriosis-associated infertility after fertilization failure with in vitro fertilization (IVF). Journal of Assisted Reproduction and Genetics.  ISSN 1058-0468.  7(8), s 351- 356
  • Bjercke, Sverre; Fedorcsak, Peter; Åbyholm, Thomas; Storeng, Ritsa; Ertzeid, Gudvor; Oldereid, Nan Birgitte; Omland, Anne Katerine & Tanbo, Tom Gunnar (2005). IVF/ICSI outcome and serum LH concentration on day 1 of ovarian stimulation with recombinant FSH under pituitary suppression. Human Reproduction.  ISSN 0268-1161.  20
  • Omland, Anne Katerine; Åbyholm, Thomas; Fedorcsak, Peter; Ertzeid, Gudvor; Oldereid, Nan Birgitte; Bjercke, Sverre & Tanbo, Tom Gunnar (2005). Pregnancy outcome after IVF and ICSI in unexplained, endometriosis-associated and tubal factor infertility . Human Reproduction.  ISSN 0268-1161.  20(3), s 722- 727
  • Lund, Hanne S.; Alstad, Heidi; Fedorcsak, Peter; Storeng, Rita & Hemmersbach, Peter J (2005). Endogenous nandrolone production: studies in granulosa cells from patients with polycystic ovary syndrom (PCOS), In Wilhelm Schänzer; Hans Geyer; Andrea Gotzmann & Ute Mareck (ed.),  Recent Advances in Doping Analysis (13).  Sportverlag Strauss.  ISBN 3-939390-13-5.  Posters.  s 483 - 486
  • Dale, P.O.; Tanbo, T; Ertzeid, Gudvor; Bjercke, S; Oldereid, N.B.; Fedorcsak, Peter & Åbyholm, Thomas (2004). The impact of insulin resistance on the outcome of laparoscopic ovarian electrocautery in infertile women with the polycystic ovary syndrome. Gynecological Endocrinology.  ISSN 0951-3590.  19, s 182- 189
  • Fedorcsak, Peter; Dale, Per Olav; Storeng, Ritsa; Ertzeid, Gudvor; Bjercke, Sverre; Oldereid, Nan; Omland, Anne K; Åbyholm, Thomas & Tanbo, Tom (2004). Impact of overweight and underweight on assisted reproduction treatment. Human Reproduction.  ISSN 0268-1161.  19(11), s 2523- 2528
  • Fedorcsak, Peter (2003). Effects of leptin and leukemia inhibitory factor on preimplantation development and STAT3 signaling of mouse embryos in vitro. Biology of Reproduction.  ISSN 0006-3363.  69, s 1531- 1538
  • Fedorcsak, Peter & Åbyholm, Thomas (2003). The effect of metformin on ovarian stimulation and in vitro fertilization in insulin resistant women with polycystic ovarian syndrome: an open randomized crossover trial. Gynecological Endocrinology.  ISSN 0951-3590.  17, s 207- 214
  • Omland, Anne Katerine; Fedorcsak, Peter; Storeng, Ritsa; Dale, Per Olav; Åbyholm, Thomas; Tanbo, Tom & Aamodt, Geir (2002). Different aetiological mechanisms for unexplained and endometriosis-associated infertility cannot be inferred from unstimulated IVF cycles using HCG to induce ovulation. Human Reproduction.  ISSN 0268-1161.  17, s 1927- 1927
  • Fedorcsak, Peter; Dale, Per Olav; Storeng, Ritsa; Tanbo, Tom & Åbyholm, Thomas (2001). The impact of obesity and insulin resistance on the outcome of IVF or ICSI in women with polycystic ovarian syndrome. Human Reproduction.  ISSN 0268-1161.  16, s 1086- 1091
  • Omland, Anne Katerine; Fedorcsak, Peter; Storeng, Ritsa; Dale, Per Olav; Åbyholm, Thomas & Tanbo, Tom (2001). Natural cycle IVF in unexplained, endometriosis-associated and tubal factor infertility. Human Reproduction.  ISSN 0268-1161.  16(12), s 2587- 2592
  • Wang, Y H.; Fedorcsak, Peter; Dale, Per Olav; Storeng, Ritsa; Åbyholm, Thomas & Tanbo, Tom (2001). Simplification of continous infusion of glucose with model assessment in the evaluation of insulin resistance in PCOS women. Gynecological Endocrinology.  ISSN 0951-3590.  15, s 192- 197
  • Fedorcsak, Peter; Storeng, Ritsa; Dale, Per Olav; Tanbo, Tom & Åbyholm, Thomas (2000). Impaired insulin action on granulosa-lutein cells from patients with polycystic ovary syndrome and insulin resistance. Gynecological Endocrinology.  ISSN 0951-3590.  14, s 327- 336
  • Fedorcsak, Peter; Storeng, Ritsa; Dale, Per Olav; Tanbo, Tom & Åbyholm, Thomas (2000). Obesity is associated with early pregnancy loss after IVF or ICSI. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  1, s 43- 48

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  • Tiller, Heidi; Fedorcsák, Péter & Skogen, Bjørn Ragnar (2016). Old tools revisited give hope - new treatment option for families with a history of severe FNAIT complications.. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  95(4), s 486- 487 . doi: 10.1111/aogs.12842 Fulltekst i vitenarkiv
  • Haavaldsen, Camilla; Fedorcsák, Péter; Tanbo, Tom Gunnar & Eskild, Anne (2015). Reply to Bang Hyun Lee et al.: Maternal age and human chorionic gonadotropin in early pregnancy: Influence of gonadotropin-releasing hormone. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  94(4), s 444 . doi: 10.1111/aogs.12583
  • Fedorcsak, Peter & Raki, Melinda (2013). Optimal gonadotropin dosage.
  • Mellembakken, Jan Roar; Berga, Sarah L.; Kilen, Mirjam; Tanbo, Tom Gunnar; Abyholm, Thomas & Fedorcsak, Peter (2011). Unchanged Fertility with Age in Women with Polycystic Ovarian Syndrome. Reproductive Sciences.  ISSN 1933-7191.  18(3), s 253A- 253A
  • Polec, Anna; Raki, Melinda; Tanbo, Tom Gunnar; Åbyholm, Thomas & Fedorcsak, Peter (2011). Interaction between Granulosa-Lutein Cells and Monocytes Regulates Secretion of Angiogenic Factors In Vitro. Reproductive Sciences.  ISSN 1933-7191.  18(3), s 279A- 279A
  • Stensen, Mette Haug; Tanbo, Tom Gunnar; Storeng, R.; Abyholm, T. & Fedorcsak, Peter (2011). Human ovarian ageing: a role of advanced glycation endproducts (AGE) and the receptor RAGE?. Human Reproduction.  ISSN 0268-1161.  26, s I235- I236
  • Opøien, Hans Kristian; Fedorcsak, Peter; Åbyholm, Thomas; Tanbo, Tom Gunnar & Tanbo, Tom (2010). Complete surgical removal of minimal and mild endometriosis improves outcome of subsequent assisted reproduction treatment. Human Reproduction.  ISSN 0268-1161.  25(Supp. 1), s I10- I10
  • Polec, Anna; Raki, Melinda; Tanbo, Tom Gunnar; Abyholm, Thomas & Fedorcsak, Peter (2010). Interaction between granulosa-lutein cells and monocytes regulates secretion of angiogenic factors in vitro. Human Reproduction.  ISSN 0268-1161.  25, s I287- I288
  • Alstad, Heidi; Lund, Hanne S.; Fedorcsak, Peter; Storeng, Rita & Hemmersbach, Peter J (2005). Endogenous nandrolone production: Studies in granulosa cells from patients with polycystic ovary syndrome (PCOS).
  • Fedorcsak, Peter (2003). Phosphorylation of STAT 3 protein in trophectoderm and inner cell mass cells of mouse blastocysts in vitro.
  • Fedorcsak, Peter & Storeng, Ritsa (2002). Fat hormone leptin impairs embryo development in mice.
  • Fedorcsak, Peter & Storeng, Ritsa (2002). Leukemia inhibitory factor (LIF) neutralizes the inhibitory effect of leptin on the preimplantation development of mouse embryos in vitro.
  • Jåthun, Solveig; Fedorcsak, Peter; Storeng, Ritsa; Lund, H.; Hemmersbach, Peter J & Torjesen, Peter A. (2002). Nandrolone (19-nortestosterone) is a by-product of the estrogen aromatase of the human ovary.
  • Jåthun, Solveig; Lund, H.; Fedorcsak, Peter; Storeng, Ritsa; Torjesen, Peter A. & Hemmersbach, Peter J (2002). Synthesis of Nandrolone in the human ovary.
  • Storeng, Ritsa; Fedorcsak, Peter; Bjerknes, G.; Frøland, E.; Haug, M.; Grøthe, A. G.; Nygaard, Egil A.; Staver, P.; Tanbo, Tom & Åbyholm, Thomas (2002). Comparison of ICSI outcome in male and non-male factor infertility.
  • Fedorcsak, Peter; Storeng, Ritsa; Dale, Per Olav; Tanbo, Tom; Torjesen, Peter A. & Åbyholm, Thomas (2000). Leptin and leptin binding activity in the preovulatory follicle of polycystic ovary syndrome.

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Publisert 8. mai 2015 10:39 - Sist endret 2. mai 2017 18:08