Johanna Olweus

Bilde av Johanna Olweus
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Telefon +47-22781325
Mobiltelefon 90054934 +47-900 54934
Brukernavn
Besøksadresse Ullernchausseen 70 0372 OSLO
Postadresse Postboks 4950 Nydalen 0424 OSLO

Leder for K.G. Jebsen-senter for immunterapi mot kreft.

Emneord: Kreft, Immunoterapi, Celler og molekyler, Livsvitenskap

Publikasjoner

Nedenfor liste over utvalgte publikasjoner.

Fullstendig publikasjonsliste her.

  • Strønen E, Toebes M, Kelderman S, van Buuren MM, Yang W, van Rooij N, Donia M, Böschen ML, Lund-Johansen F, Olweus J, Schumacher TN.Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science. 2016 May 19. pii: aaf2288. [Epub ahead of print] PMID: 27198675

  • Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J. Sequential intranodal immuntherapy induces anti-tumor immunity and correlated regression of disseminated follicular lymphoma. Blood 2014 Oct 7 pii: blood-2014-07-592162. [Epub ahead of print]
  • Kumari S, Walchli S, Fallang LE, Yang W, Lund-Johansen F, Schumacher TN, Olweus J. Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes. Proc Natl Acad Sci U S A. 2014;111(1):403-408.
    Selected by Faculty of 1000 Prime:http://f1000.com/prime/718206020?bd=1 (Two stars)
  • Lossius A, Johansen JN, Vartdal F, Robins H, Benth JS, Holmoy T, Olweus J. High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8 T cells. Eur J Immunol. 2014.
  • Walchli S, Kumari S, Fallang LE, Sand KM, Yang W, Landsverk OJ, . . . Olweus J*, Gregers TF*. Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. Eur J Immunol. 2014;44(3):774-784.
     *Shared senior authors. Front cover. Commentary in Eur J Immunol 2014, V44, p650
    Selected by Faculty of 1000 Prime: http://f1000.com/prime/718194774?bd=1&ui=28053
  • Taraldsrud E, Fevang B, Aukrust P, Beiske KH, Floisand Y, Froland S, . . . Olweus J. Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9. 
    Clin Exp Immunol. 2014;175(3):439-448.
  • Abrahamsen IW, Kjellevoll S, Greve-Isdahl M, Mensali N, Walchli S, Kumari S, . . . Olweus J. T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells. Int J Cancer. 2012;130(8):1821-1832.
  • Abrahamsen IW, Stronen E, Walchli S, Johansen JN, Kjellevoll S, Kumari S, . . . Olweus J. Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif. Leukemia. 2010;24(11):1901-1909.

     
  • Henriksen, Eva Kristine Klemsdal; Jørgensen, Kristin Kaasen; Kaveh, Fatemeh; Holm, Kristian; Hamm, David; Olweus, Johanna; Melum, Espen; Chung, Brian; Eide, Tor Jacob; Lundin, Knut Erik Aslaksen; Boberg, Kirsten Muri; Karlsen, Tom Hemming; Hirschfield, Gideon M. & Liaskou, Evaggelia (2017). Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease. Journal of Hepatology.  ISSN 0168-8278.  66(1), s 116- 122 . doi: 10.1016/j.jhep.2016.09.002
  • Taraldsrud, Eli; Aukrust, Pål; Jørgensen, Silje; Lingjærde, Ole Christian; Olweus, Johanna; Myklebust, June & Fevang, Børre (2017). Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency. Clinical Immunology.  ISSN 1521-6616.  175, s 69- 74 . doi: 10.1016/j.clim.2016.11.014 Vis sammendrag
  • Taraldsrud, Eli; Fevang, Børre; Jørgensen, Silje Fjellgård; Moltu, Kristine; Hilden, Vera Irene; Tasken, Kjetil; Aukrust, Pål; Myklebust, June & Olweus, Johanna (2017). Defective IL-4 signaling in T cells defines severe common variable immunodeficiency. Journal of Autoimmunity.  ISSN 0896-8411.  81, s 110- 119 . doi: 10.1016/j.jaut.2017.04.004
  • Liaskou, Evaggelia; Henriksen, Eva Kristine Klemsdal; Holm, Kristian; Kaveh, Fatemeh; Hamm, D; Fear, Janine; Viken, Marte K; Hov, Johannes Espolin Roksund; Melum, Espen; Robins, Harlan; Olweus, Johanna; Karlsen, Tom Hemming & Hirschfield, GM (2016). High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires. Hepatology.  ISSN 0270-9139.  63(5), s 1608- 1619 . doi: 10.1002/hep.28116 Vis sammendrag
  • Mensali, Nadia; Fan, Ying; Oei, Vincent Yi Sheng; Yang, Weiwen; Walseng, Even; Kumari, Shraddha; Fallang, Lars-Egil; Kolstad, Arne; Uckert, Wolfgang; Malmberg, Karl-Johan; Waelchli, Sebastien & Olweus, Johanna (2016). Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA. Oncoimmunology.  ISSN 2162-402X.  5:e1138100(5) . doi: 10.1080/2162402X.2016.1138199
  • Strønen, Erlend; Toebes, Mireille; Kelderman, Sander; van Buuren, Marit M.; Yang, Weiwen; Van Rooij, Nienke; Donia, Marco; Bøschen, Maxi-Lu; Lund-Johansen, Fridtjof; Olweus, Johanna & Schumacher, Ton N. (2016). Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science.  ISSN 0036-8075.  352(6291), s 1337- 1341 . doi: 10.1126/science.aaf2288
  • Kärpänen, Terhi Hannele & Olweus, Johanna (2015). T-cell receptor gene therapy - ready to go viral?. Molecular Oncology.  ISSN 1574-7891.  9(10), s 2019- 2042 . doi: 10.1016/j.molonc.2015.10.006
  • Kolstad, Arne; Kumari, Shraddha; Walczak, Mateusz; Madsbu, Ulf Erik; Hagtvedt, Trond; Bogsrud, Trond; Kvalheim, Gunnar; Holte, Harald; Aurlien, Ellen; Delabie, Jan; Tierens, Anne & Olweus, Johanna (2015). Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma. Blood.  ISSN 0006-4971.  125(1), s 82- 89 . doi: 10.1182/blood-2014-07-592162
  • Tadesse, Fitsum G.; Mensali, Nadia; Fallang, Lars-Egil; Walseng, Even; Yang, Weiwen; Olweus, Johanna & Waelchli, Sebastien (2015). Unpredicted phenotypes of two mutants of the TcR DMF5. JIM - Journal of Immunological Methods.  ISSN 0022-1759.  425, s 37- 44 . doi: 10.1016/j.jim.2015.06.006 Vis sammendrag
  • Walseng, Even; Waelchli, Sebastien; Fallang, Lars-Egil; Yang, Weiwen; Vefferstad, Anette; Areffard, Mohammad Ali & Olweus, Johanna (2015). Soluble T-cell receptors produced in human cells for targeted delivery. PLoS ONE.  ISSN 1932-6203.  10(4) . doi: 10.1371/journal.pone.0119559
  • Kumari, Shraddha; Waelchli, Sebastien; Fallang, Lars-Egil; Yang, Weiwen; Lund-Johansen, Fridtjof; Schumacher, Ton N. & Olweus, Johanna (2014). Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  111(1), s 403- 408 . doi: 10.1073/pnas.1306549111
  • Lossius, Peter Andreas Vold; Johansen, Jorunn; Vartdal, Frode; Robins, Harlan; Saltyte Benth, Jurate; Holmøy, Trygve & Olweus, Johanna (2014). High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells. European Journal of Immunology.  ISSN 0014-2980.  44(11), s 3439- 3452 . doi: 10.1002/eji.201444662
  • Taraldsrud, Eli; Fevang, Børre; Aukrust, Pål; Beiske, Klaus; Fløisand, Yngvar; Frøland, Stig Sophus; Rollag, Halvor & Olweus, Johanna (2014). Common variable immunodeficiency revisited: Normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9. Clinical and Experimental Immunology.  ISSN 0009-9104.  175(3), s 439- 448 . doi: 10.1111/cei.12239
  • Waelchli, Sebastien; Kumari, Shraddha; Fallang, Lars-Egil; Sand, Kine Marita Knudsen; Yang, Weiwen; Landsverk, Ole J. B.; Bakke, Oddmund; Olweus, Johanna & Gregers, Tone Fredsvik (2014). Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. European Journal of Immunology.  ISSN 0014-2980.  44(3), s 774- 784 . doi: 10.1002/eji.201343671
  • Abrahamsen, Ingerid Weum; Kjellevoll, Synneva; Greve-Isdahl, Margrethe; Mensali, Nadia; Waelchli, Sebastien; Kumari, Shraddha; Løland, Beate Fossum; Egeland, Torstein; Kolstad, Arne & Olweus, Johanna (2012). T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells. International Journal of Cancer.  ISSN 0020-7136.  130(8), s 1821- 1832 . doi: 10.1002/ijc.26209
  • Wälchli, Sebastien; Løset, Geir Åge; Kumari, Shraddha; Johansen, Jorunn; Yang, Weiwen; Sandlie, Inger & Olweus, Johanna (2011). A Practical Approach to T-Cell Receptor Cloning and Expression. PLoS ONE.  ISSN 1932-6203.  6(11) . doi: 10.1371/journal.pone.0027930 Fulltekst i vitenarkiv.
  • Abrahamsen, Ingerid Weum; Strønen, Erlend; Waelchli, Sebastien; Johansen, Jorunn; Kumari, Shraddha; Komada, M; Gaudernack, Gustav; Tjønnfjord, Geir Erland; Toebes, M; Schumacher, TN; Lund-Johansen, Fridtjof; Olweus, Johanna & Kjellevoll, Synneva (2010). Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif. Leukemia.  ISSN 0887-6924.  24(11), s 1901- 1909 . doi: 10.1038/leu.2010.186
  • Rölle, Alexander & Olweus, Johanna (2009). Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS).  ISSN 0903-4641.  117(5-6), s 413- 426 . doi: 10.1111/j.1600-0463.2009.02449.x
  • Strønen, Erlend; Abrahamsen, Ingerid Weum; Gaudernack, Gustav; Waelchli, Sebastien; Munthe, Else; Buus, S; Johansen, Finn Eirik; Lund-Johansen, Fridtjof & Olweus, Johanna (2009). Dendritic Cells Engineered to Express Defined Allo-HLA Peptide Complexes Induce Antigen-specific Cytotoxic T Cells Efficiently Killing Tumour Cells. Scandinavian Journal of Immunology.  ISSN 0300-9475.  69(4), s 319- 328 . doi: 10.1111/j.1365-3083.2008.02223.x
  • Kvale, Espen Østhagen; Fløisand, Yngvar; Lund-Johansen, Fridtjof; Rollag, Halvor; Farkas, Lorant; Ghanekar, Smita; Brandtzæg, Per; Jahnsen, Frode Lars & Olweus, Johanna (2007). Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells. Blood.  ISSN 0006-4971.  109 . doi: 10.1182/blood-2006-06-031484
  • Villa, Iris Kristine; Kvale, Espen Østhagen; Lund-Johansen, Fridtjof & Olweus, Johanna (2007). Assay for monitoring in vitro selective depletion strategies in allogeneic stem cell transplantation. Cytotherapy.  ISSN 1465-3249.  9, s 600- 610 . doi: 10.1080/14653240701510573
  • Kvale, Espen Østhagen; Dalgaard, Jakob; Lund-Johansen, Fridtjof; Rollag, Halvor; Farkas, Lorant; Midtvedt, Karsten; Jahnsen, Frode Lars; Brinchmann, Jan E. & Olweus, Johanna (2006). CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell–stimulatory capability upon infection. Blood.  ISSN 0006-4971.  107(5), s 2022- 2029 . doi: 10.1182/blood-2005-05-2016
  • Kolstad, Arne & Olweus, Johanna (2015). “In situ” vaccination for systemic effects in follicular lymphoma. Oncoimmunology.  ISSN 2162-402X.  4(7), s 1- 3 . doi: 10.1080/2162402X.2015.1014773
  • Olweus, Johanna (2015). Cancer immunotherapy - Converting immune failure to clinical response. Molecular Oncology.  ISSN 1574-7891.  9(10), s 1891- 1893 . doi: 10.1016/j.molonc.2015.10.017
  • Regenthal, P; Wälchli, S; Fallang, Lars-Egil; Olweus, Johanna & Lindkvist-Petersson, K (2013). Structural Modeling Provides Means to Understand the Binding Specificity of Alloreactive T Cells. Scandinavian Journal of Immunology.  ISSN 0300-9475.  77(4), s 314- 315
  • Inderberg-Suso, Else M.; Wälchli, Sebastien; Myhre, Marit Renee; Yang, Weiwen; Trachsel, Sissel; Olweus, Johanna; Wang, Mengyu; Kvalheim, Gunnar & Gaudernack, Gustav (2012). Targeting Microsatellite Instable Colon Cancer With Adoptively Transferred Redirected T cells. Journal of immunotherapy (1997).  ISSN 1524-9557.  35(9), s 724- 724
  • Taraldsrud, Eli; Floisand, Y; Aukrust, Pål; Rollag, Halvor; Fevang, Børre & Olweus, Johanna (2012). PLASMACYTOID DENDRITIC CELLS HAVE NORMAL FUNCTION IN PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY. Journal of Clinical Immunology.  ISSN 0271-9142.  32, s 50- 50
  • Wälchli, Sebastien; Landsverk, Ole J. B.; Fallang, Lars-Egil; Olweus, Johanna; Bakke, Oddmund & Gregers, Tone Fredsvik (2012). Invariant chain as a tool to load antigenic peptides on MHC class I. Molecular Immunology.  ISSN 0161-5890.  51(1), s 16- 16 . doi: 10.1016/j.molimm.2012.02.039
  • Abrahamsen, Ingerid Weum & Olweus, Johanna (2011). Targeting cancer by donor immunity. Series of dissertations submitted to the Faculty of Medicine, University of Oslo. 1107.
  • Kolstad, Arne; Kumari, Shraddha; Kvalheim, Gunnar; Bogsrud, Trond; Madsbu, Ulf Erik; Hagtvedt, Trond; Gaudentack, Gustav; Lauvvang, Grethe; Holte, Harald & Olweus, Johanna (2010). A Novel Cancer Vaccine Strategy In Previously Untreated Patients with Stage III/IV Follicular Lymphoma Generates Tumor-Reactive T Cells and Clinical Response. Blood.  ISSN 0006-4971.  116(21), s 753- 754
  • Olsen, Dag Rune; Olweus, Johanna & Martinsen, Ørjan Grøttem (2009, 20. mars). Kvantemedisin - Mirakelmaskin eller bedrageri?. [TV].  NRK Schrødingers katt.
  • Kvale, Espen Østhagen; Fløisand, Yngvar; Lund-Johansen, Fridtjof; Rollag, Halvor; Brandtzæg, Per; Jahnsen, Frode Lars & Olweus, Johanna (2006). Plasmacytoid dendritic cells regulate recall responses by rapid induction of IL-10 in CD4+ memory T cells. Tissue Antigens.  ISSN 0001-2815.  67, s 443- 444
Publisert 13. apr. 2011 11:42 - Sist endret 27. mai 2016 11:42