Publications

1.  Falk JF*, Lee J*, Sekulic N, Sennett MA, Lee TH, Black BE. CENP-C directs a structural transition of the CENP-A nucleosome mainly through sliding of DNA gyres. Nat Struct Mol Biol. (accepted)

* - equal contribution

2. McKinley KL, Sekulic N, Guo LY, Tsinman T, Black BE, Cheeseman IM. The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface. Mol Cell. 2015 Dec 17;60(6):886-98. 

3. Falk JS*, Guo JY*, Sekulic N*, Smoak EM*, Mani T, Logsdon G, Gupta K, Jansen LT, Van Duyne GV, Vinogradov SA, Lampson MA, and Black BE. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science. 2015 May 8;348(6235):699-703

* - equal contributions

4. Geiss CP, Keramisanou D, Sekulic N, Scheffer MP, Black BE, Frangakis AS. CENP-A Arrays Are More Condensed than Canonical Arrays at Low Ionic Strength. Biochem J. 2014 Feb 18;106(4):875-82

5. Hasson D, Panchenko T, Salimian KJ, Salman MU, Sekulic N, Alonso A, Warburton PE, and Black BE. The octamer is the major form of CENP-A nucleosomes at human centromeres. Nat Struct Mol Biol. 2013 Jun;20(6):687-95

6. Sekulic N, Black BE. Molecular underpinnings of centromere identity and maintenance. Trends Biochem Sci. 2012 Jun;37(6):220-9. Review (featured at the cover page)

7. Bassett EA, DeNizio J, Barnhart-Dailey MC, Panchenko T, Sekulic N, Rogers DJ, Foltz DR, Black BE. HJURP uses distinct CENP-A surfaces to recognize and to stabilize CENP-A/histone H4 for centromere assembly. Dev Cell. 2012 Apr 17;22(4):749-62.

8. Sekulic N, Bassett EA, Rogers DJ, Black BE. The structure of (CENP-A-H4)2 reveals physical features that mark centromeres. Nature. 2010 Sep 16;467(7313):347-51

9. Sekulic N, Black BE. A reader for centromeric chromatin. Nat Cell Biol. 2009 Jul;11(7):793-5.

10. Sekulic N, Konrad M, Lavie A. Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation. J Biol Chem. 2007 Jul 27;282(30):22112-21.

11. Sekulic N, Dietrich K, Parmaan I,Ort, S, Konrad M, Lavie A. Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1. J Mol Biol. 2007 Mar 23; 367(2):488-500.

12. Sekulic N, Shuvalova L, Spangenberg O, Konrad M, Lavie A. Structural characterization of the closed conformation of the mouse gunylate kinase. J Biol Chem. 2002 Aug 16; 277(33):30236-43.

Published Feb. 1, 2016 9:57 AM - Last modified Feb. 1, 2016 9:57 AM