Nikolai Engedal

Image of Nikolai Engedal
Norwegian version of this page
Phone +47-22840765
Visiting address Gaustadalléen 21 Forskningsparken 0349 OSLO
Postal address Postboks 1137 Blindern 0318 OSLO

Current roles

  • Project Leader of the Autophagy in Prostate Cancer project group at NCMM. This group consist of two PhD students, Morten Luhr and Paula Szalai, and also guest researcher and autophagy expert, Per Seglen. This group was part of the previous research group of Ian Mills (2010-2016).
  • Coordinator of Nordic Autophagy Network
  • Task Manager and Norwegian representative on the Board of EU COST (European Cooperation in Science and Technology) action on Autophagy (Transautophagy).

Past roles

  • Previously a member of the Ian Mills Prostate Cancer Group.
Tags: Cancer research, Cancer, Cell signalling, Cell biology, Membrane trafficking, Autophagy, Cell death


  • Engedal, Kim Nikolai & Seglen, Per O. (2016). Autophagy of cytoplasmic bulk cargo does not require LC3. Autophagy.  ISSN 1554-8627.  12(2), s 439- 441 . doi: 10.1080/15548627.2015.1076606
  • Itkonen, Harri; Engedal, Kim Nikolai; Babaie, Eshrat; Luhr, Morten; Guldvik, Ingrid Jenny; Minner, S; Hohloch, J; Tsourlakis, MC; Schlomm, Thorsten & Mills, Ian Geoffrey (2015). UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation. Oncogene.  ISSN 0950-9232.  34(28), s 3744- 3750 . doi: 10.1038/onc.2014.307
  • Seglen, Per O.; Luhr, Morten; Mills, Ian Geoffrey; Sætre, Frank; Szalai, Paula & Engedal, Kim Nikolai (2015). Macroautophagic cargo sequestration assays. Methods.  ISSN 1046-2023.  75, s 25- 36 . doi: 10.1016/j.ymeth.2014.12.021
  • Szalai, Paula; Hagen, Linda K Korsberg; Sætre, Frank; Luhr, Morten; Sponheim, Marianne; Øverbye, Anders; Mills, Ian Geoffrey; Seglen, Per O. & Engedal, Kim Nikolai (2015). Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs. Experimental Cell Research.  ISSN 0014-4827.  333(1), s 21- 38 . doi: 10.1016/j.yexcr.2015.02.003
  • Sætre, Frank; Hagen, Linda K Korsberg; Engedal, Kim Nikolai & Seglen, Per O. (2015). Novel steps in the autophagic-lysosomal pathway. The FEBS Journal.  ISSN 1742-464X.  282(11), s 2202- 2214 . doi: 10.1111/febs.13268
  • Engedal, Kim Nikolai & Mills, Ian Geoffrey (2014). Endosomal signalling and oncogenesis. Methods in Enzymology.  ISSN 0076-6879.  535, s 179- 200 . doi: 10.1016/B978-0-12-397925-4.00012-2
  • Engedal, Kim Nikolai; Torgersen, Maria Lyngaas; Guldvik, Ingrid Jenny; Barfeld, Stefan; Bakula, D; Sætre, Frank Ove; Hagen, Linda K Korsberg; Patterson, J; Proikas-Cezanne, T; Seglen, Per O.; Simonsen, Anne & Mills, Ian Geoffrey (2013). Modulation of intracellular calcium homeostasis blocks autophagosome formation. Autophagy.  ISSN 1554-8627.  9(10), s 1475- 1490 . doi: 10.4161/auto.25900
  • Kvalvaag, Audun Sverre Myrset; Pust, Sascha; Sundet, Kristine Ingrid; Simm, Roger; Sandvig, Kirsten & Engedal, Kim Nikolai (2013). The ERM Proteins Ezrin and Moesin Regulate Retrograde Shiga Toxin Transport. Traffic : the International Journal of Intracellular Transport.  ISSN 1398-9219.  14(7), s 839- 852 . doi: 10.1111/tra.12077
  • Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Bøe, Stig Ove; Hokland, Peter & Simonsen, Anne (2013). Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells. Blood.  ISSN 0006-4971.  122(14), s 2467- 2476 . doi: 10.1182/blood-2013-05-500629
  • Engedal, Kim Nikolai (2011). Chapter seven - Immune Regulator Vitamin A and T Cell Death. Vitamines and Hormones.  ISSN 0083-6729.  86, s 153- 178 . doi: 10.1016/B978-0-12-386960-9.00007-1
  • Engedal, Kim Nikolai; Skotland, Tore; Torgersen, Maria Lyngaas & Sandvig, Kirsten (2011). Shiga toxin and its use in targeted cancer therapy and imaging. Microbial Biotechnology.  ISSN 1751-7907.  4(1), s 32- 46 . doi: 10.1111/j.1751-7915.2010.00180.x
  • Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje & Sandvig, Kirsten (2011). Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology.  ISSN 0928-8244.  61(1), s 63- 75 . doi: 10.1111/j.1574-695X.2010.00749.x
  • Sandvig, Kirsten; Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Skotland, Tore & Iversen, Tore Geir (2010). Protein toxins from plants and bacteria: Probes for intracellular transport and tools in medicine. FEBS Letters.  ISSN 0014-5793.  584(12), s 2626- 2634 . doi: 10.1016/j.febslet.2010.04.008
  • Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Bergan, Jonas & Sandvig, Kirsten (2010). The intracellular journey of Shiga toxins. Open Toxinology Journal.  ISSN 1875-4147.  3, s 3- 12
  • Engedal, Kim Nikolai; Auberger, P & Blomhoff, Heidi Kiil (2009). Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly. Journal of Leukocyte Biology.  ISSN 0741-5400.  85(3), s 469- 480 . doi: 10.1189/jlb.1107790
  • Engedal, Kim Nikolai; Gjevik, Tone; Blomhoff, Rune & Blomhoff, Heidi Kiil (2006). All-trans retinoic acid stimulates IL-2-mediated proliferation of human T lymphocytes: Early induction of cyclin D3(1). Journal of Immunology.  ISSN 0022-1767.  177, s 2851- 2861
  • Engedal, Kim Nikolai; Ertesvåg, Åse & Blomhoff, Heidi Kiil (2004). Survival of activated human T lymphocytes is promoted by retinoic acid via induction of IL-2. International Immunology.  ISSN 0953-8178.  16, s 443- 453

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  • Wergeland, Jon Normann; Kirkevold, Øyvind; Selbæk, Geir; Høgset, Lisbeth Dyrendal & Engedal, Kim Nikolai (2011). Depression and dementia among elderly receiving in-home health care and social care. International psychogeriatrics.  ISSN 1041-6102.  23, s S201- S202

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Published Dec. 5, 2016 4:45 PM - Last modified Mar. 28, 2017 12:56 PM