Sigrid Skånland

Bilde av Sigrid Skånland
English version of this page
Telefon +47-22859128
Rom 52115
Brukernavn
Besøksadresse Forskningsparken Gaustadalléen 21 0349 Oslo
Postadresse Postboks 1137 Blindern 0318 OSLO
Andre tilknytninger Institutt for kreftforskning

Mer informasjon finnes på den engelske versjonen av denne siden.

Faglige interesser

Mekanismer involvert i aktiveringen av regulatoriske T-celler (Tregs).

Nåværende stilling

  • Postdoktor, Kjetil Taskén Biotek Group (Cell Signalling , Bioteknologisenteret i Oslo.

Bakgrunn

Forskning:

  • 2009 - 2011:  Postdoktor i Prof. Ivan Dikic gruppe, Institut for Biokjemi II, Johan Wolfgang Goethe University, Frankfurt, Tyskland.
  • 2006:  Gjestestudent (3 måneder) i Prof. Tom Rapoports gruppe, Avdeling for cellebiologi, Harvard Medical School, Boston, MA, USA.

Utdanning:

  • 2008:  Doktograd, Prof. Kirsten Sandvigs gruppe, Radiumhospitalet, Universitet i Oslo.
  • Doktoravhandling:  "Mechanisms in intracellular transport of toxins." 
  • 2005:  Mastergrad i Molekylærbiologi, Prof. Kirsten Sandvigs gruppe, Rikshospitalet, Universitet i Oslo.
    Masteravhandling:  "The phosphatidylinositol 3-kinase hVps34 modulates endosome to Golgi transport of ricin."
  • 2002:  Bachelorgrad i Biologi, det Matematisk-naturvitenskapelige fakultet, Universitet i Olso.

Tilskudd

  • 2009 - 2011:  EMBO Long term fellowship.
Emneord: Cellesignallering, Kreft, Regulatoriske T-celler, Kronisk lymfatisk leukemi, Immunologi, Kreftforskning, B celler, T-celler

Publikasjoner

  • Myhrvold, Ida Kristin; Cremaschi, Andrea; Hermansen, Johanne Uthus; Tjønnfjord, Geir Erland; Munthe, Ludvig Andre; Tasken, Kjetil & Skånland, Sigrid Strand (2018). Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia. OncoTarget.  ISSN 1949-2553.  9(10), s 9273- 9284 . doi: 10.18632/oncotarget.23949
  • Skånland, Sigrid Strand; Moltu, Kristine; Berge, Torunn; Aandahl, Einar Martin & Tasken, Kjetil (2014). T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses. Biochemical Journal.  ISSN 0264-6021.  460(3), s 399- 410 . doi: 10.1042/BJ20140040
  • Gregers, Tone Fredsvik; Skånland, Sigrid Strand; Waelchli, Sebastien; Bakke, Oddmund & Sandvig, Kirsten (2013). BiP Negatively Affects Ricin Transport. Toxins.  ISSN 2072-6651.  5(5), s 969- 982 . doi: 10.3390/toxins5050969
  • Pollheimer, Jürgen; Bodin, Johanna; Sundnes, Olav; Bekkeheien, Reidunn C; Skånland, Sigrid Strand; Sponheim, Jon; Brox, Mari Johanna; Sundlisæter, Eirik; Loos, Tamara; Vatn, Morten H; Kasprzycka, Monika; Wang, Junbai; Kuchler, Axel Matthias; Tasken, Kjetil; Haraldsen, Guttorm & Hol, Johanna (2013). Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells. Arteriosclerosis, Thrombosis and Vascular Biology.  ISSN 1079-5642.  33(2), s e47- e55 . doi: 10.1161/ATVBAHA.112.253427
  • Kalland, Maria Elisabeth; Solheim, Silje Anette; Skånland, Sigrid Strand; Tasken, Kjetil & Berge, Torunn (2012). Modulation of proximal signaling in normal and transformed B cells by transmembrane adapter Cbp/PAG. Experimental Cell Research.  ISSN 0014-4827.  318(14), s 1611- 1619 . doi: 10.1016/j.yexcr.2012.05.014
  • Tcatchoff, Lionel; Andersson, Sofia; Utskarpen, Audrun; Klokk, Tove Irene; Skånland, Sigrid Strand; Pust, Sascha; Gerke, Volker & Sandvig, Kirsten (2012). Annexin A1 and A2: Roles in Retrograde Trafficking of Shiga Toxin. PLoS ONE.  ISSN 1932-6203.  7(7) . doi: 10.1371/journal.pone.0040429
  • Skånland, Sigrid Strand; Walchli, S & Sandvig, Kirsten (2009). beta-arrestins attenuate p38-mediated endosome to Golgi transport. Cellular Microbiology.  ISSN 1462-5814.  11(5), s 796- 807 . doi: 10.1111/j.1462-5822.2009.01292.x
  • Skånland, Sigrid Strand; Wälchli, Sebastien; Brech, Andreas & Sandvig, Kirsten (2009). SNX4 in complex with clathrin and dynein: Implications for endosome movement. PLoS ONE.  ISSN 1932-6203.  s e5935 . doi: 10.1371/journal.pone.0005935
  • Wälchli, Sebastien; Aasheim, Hans-Christian; Skånland, Sigrid Strand; Spilsberg, Bjørn; Torgersen, M.L.; Rosendal, Ken & Sandvig, Kirsten (2009). Characterization of clathrin and Syk interaction upon Shiga toxin binding. Cellular Signalling.  ISSN 0898-6568.  21(7), s 1161- 1168 . doi: 10.1016/j.cellsig.2009.03.005
  • Walchli, S; Skånland, Sigrid Strand; Gregers, Tone Fredsvik; Lauvrak, Silje Anett Ugland; Torgersen, Maria Lyngaas; Ying, M; Kuroda, S; Maturana, A & Sandvig, Kirsten (2008). The mitogen-activated protein kinase p38 links Shiga toxin-dependent signaling and trafficking. Molecular Biology of the Cell.  ISSN 1059-1524.  19(1), s 95- 104 . doi: 10.1091/mbc.E07-06-0565
  • Skånland, Sigrid Strand; Waelchli, Sebastien; Utskarpen, Audrun; Wandinger-Ness, A & Sandvig, Kirsten (2007). Phosphoinositide-regulated retrograde transport of ricin: Crosstalk between hVps34 and sorting nexins. Traffic : the International Journal of Intracellular Transport.  ISSN 1398-9219.  8, s 297- 309 . doi: 10.1111/j.1600-0854.2006.00527.x
  • Torgersen, M.L.; Walchli, S; Grimmer, Stine J Staavi; Skånland, Sigrid Strand & Sandvig, Kirsten (2007). PKC is activated by Shiga toxin and regulates its transport. Journal of Biological Chemistry.  ISSN 0021-9258.  282, s 16317- 16328 . doi: 10.1074/jbc.M610886200
  • Utskarpen, Audrun; Slagsvold, Hege Holte; dyve, ab; Skånland, Sigrid Strand & Sandvig, Kirsten (2007). SNX1 and SNX2 mediate retrograde transport of Shiga toxin. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  358, s 566- 570 . doi: 10.1016/j.bbrc.2007.04.159

Se alle arbeider i Cristin

  • Ribes, Anna Maria Parente; Skånland, Sigrid Strand; Bürgler, Simone; Os, Audun; Wang, Dong; Bogen, Bjarne; Tjønnfjord, Geir Erland; Tasken, Kjetil & Munthe, Ludvig Andre (2016). Spleen tyrosine kinase inhibitors reduce CD40l-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells. Haematologica.  ISSN 0390-6078.  101(2), s e59- e62 . doi: 10.3324/haematol.2015.135590
  • Moltu, Kristine; Skånland, Sigrid Strand; Berge, Torunn & Tasken, Kjetil (2012). Distinct signalling patterns and functional responses to CD2 and CD28 co-stimulation of human primary T cells. Immunology.  ISSN 0019-2805.  137, s 374- 374
  • Skånland, Sigrid Strand & Sandvig, Kirsten (2009). Mechanisms in intracellular transport of toxins. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 818.

Se alle arbeider i Cristin

Publisert 6. mai 2016 19:05 - Sist endret 31. jan. 2017 15:11