Hilde Irene Nebb

Vice-Dean for internationalization and innovation
Image of Hilde Irene Nebb
Norwegian version of this page
Phone +47-22845308
Mobile phone +47-41552925
Username
Visiting address Klaus Torgårds vei 3 Sogn Arena 0372 Oslo
Postal address Postboks 1078 Blindern 0316 Oslo

Vice-Dean for internationalization and innovation 2019–2022

Academic interests

  • Molecular nutrition
  • Nutrition
  • Transcription factors (nuclear receptors) in control of lipid- and glucose homestasis in health and disease
  • Energy balance
  • Lifestyle diseases

Courses taught

  • ERN 4210 (Topic: Molecular nutrition)
  • ERN 3110 (Topic: The molecular biology of fat)
  • PBL 2nd semester

No teaching in the period, 2011-2014 due to the sub-dean of research position at Medical faculty.

Brief introduction to previous education and employment

Education

  • 1989: Cand.scient cell biology - Institute of biology, Faculty of natural sciences, University of Oslo
  • 1993: Dr.Philos - Department of biochemistry, Institute of basic medical sciences, Medical faculty, University of Oslo

Employment

  • 2011 - : Sub-dean of research, Medical faculty, University of Oslo
  • 2005 - : Professor, Department of nutrition, Institute of basic medical sciences, Medical faculty, University of Oslo
  • 2000 - 2005: Associate professor, Department of nutrition, Institute of basic medical sciences, Medical faculty, University of Oslo
  • 1998 - 2000: Researcher, Department of nutrition, Institute of basic medical sciences, Medical faculty, University of Oslo
  • 1994 - 1998: Post.Doc, Department of biochemistry, Institute of basic medical sciences, Medical faculty, University of Oslo
  • 1993 - 1994: Research fellow, Department of biochemistry, Institute of basic medical sciences, Medical faculty, University of Oslo

 Honoraria

  • EUs Descartes research prize 2005 – excellence in collaborative research http://www.apollon.uio.no/vis/art/2005_4/Artikler/budbringermedisin.

Collaboration

 National and International collaborators

  • Work package leader in the EU-6th Framework (IP) (2006-2011) Consortium for Research into Nuclear Receptors in Development and Aging (CRESCENDO). 
  • Prof. Jan Borén, Wallenberg Laboratory, Sahlgrenska University Hospital, Göteborg, Sweden Wallenberg Laboratory,  Wa
  • Prof. Stephen Farmer, Boston University, Boston, MI, USA
  • Prof. Shigeaki Kato, University of Tokyo, Japan
  • Prof. Suanne Mandrup, Post.doc Ronni Nielsen, Prof Jens Andersen and Post.Doc Jakob Bunkenborg, University of Southern Denmark
  • Krister Bamberg, AstraZeneca, Sweden
  • Prof. Peter Voshol, Leiden University, Netherland
  • Prof Franck Delaunay and researcher Michele Teboul, Université de Nice, CNRS, France
  • Prof Jan Åke Gustafsson, NOVUM, Sweden and Houston Texas, USA
  • Researcher Ingemar Pongratz, NOVUM, Sweden
  • Prof. Gunnar Melgren, Haukeland University Hospital, Bergen, Norway
  • Prof. Helga Refsum, Prof. Christian Drevon, Prof. Guro Valen, Prof. Sigbjørn Fossum, Prof. Kirsten Holven, Institute of Medical Sciences, Medical Faculty, UiO, Norway.
  • Prof Arild Rustan, Pharmaceutical Institute, UiO, Norway
  • Prof. Kåre Birkeland, Prof. Serena Tonstad,  Prof. Bente Halvorsen, Prof. Pål Aukrust, Prof. Stig Frøland Oslo University hospital, Norway

Industrial collaborators

  • AstraZeneca, Göteborg, Sweden (1999 - )
  • Pronova, Norway  (2005 -)
  • ClavisPharma, Norway (2002 - 2010)

 

Tags: Management, Molecular nutrition, Nutrients, metabolism, energy balance, lifestyle diseases, Diabetes and hormones, Life science

Publications

Weedon-Fekjaer MS, Dalen KT, Solaas K, Staff AC, Duttaroy AK, Nebb HI. Activation of LXR increases acyl-CoA synthase activity through direct regulation of ACSL3 in human placental trophoblast cells.  J Lipid Res. (2010) Sep;31(9):818-24.

Anthonisen EH, Berven L, Holm S, Nygård M, Nebb HI* and Grønning-Wang LM*. The Nuclear Receptor LXR is O-GlcNAc Modified in Response to Glucose. J Biol Chem. (2010) Jan 15;285(3):1607-15 [* contributed Equally].

Dalen, K. T., Dahl, T., Holter, E., Arntsen, BM., Londos, C., Sztalryd, C., and Nebb, HI LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues. Biochim Biophys Acta Lipids. (2007) Feb;1771(2):210-27, 2007.

Dalen, K. T., Ulven, S. M., Arntsen, B. M., Solaas, K., and Nebb, HI. Adipose differentiation-related protein is a fasting induced PAT protein that facilitates lipid accumulation in liver J Lipid Res. (2006) May;47(5):931-43.

Ulven, S. M., Dalen, K. T., Gustafsson, J. A., and Nebb, HI. Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue.Journal of Lipid Research (2004) 45(11): 2052-2062.

Dalen, K. T., Schoonjans, K., Ulven, S. M., Weedon-Fekjaer, M. S., Bentzen, T. G., Koutnikova, H., Auwerx, J., and Nebb, HI.  Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma. Diabetes  (2004) 53(5): 1243-1252.

Dalen, K. T., Ulven, S. M., Bamberg, K., Gustafsson, J. A., and Nebb, HI.  Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha. J Biol Chemistry (2003) 278(48): 48283-48291.

Juvet, L. K., Andresen, S. M., Schuster, G. U., Dalen, K. T., Tobin, K. A., Hollung, K., Haugen, F., Jacinto, S., Ulven, S. M., Bamberg, K., Gustafsson, J. A., and Nebb, HI.  On the role of liver X receptors in lipid accumulation in adipocytes. Molecular Endocrinology (2003) 17(2): 172-182.

Tobin, K. A., Ulven, S. M., Schuster, G. U., Steineger, H. H., Andresen, S. M., Gustafsson, J. A., and Nebb, HI. Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J Biol Chemistry (2002) 277(12): 10691-10697.

Tobin, K. A., Steineger, H. H., Alberti, S., Spydevold, O., Auwerx, J., Gustafsson, J. A., and Nebb, HI. Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Molecular Endocrinology (2000) 14(5): 741-752.

  • Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie; Lucas, Christin & Vekterud, Kristin [Show all 15 contributors for this article] (2020). LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction. Cells. ISSN 2073-4409. 9(5), p. 1–26. doi: 10.3390/cells9051214. Full text in Research Archive
  • Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin & Vekterud, Kristin [Show all 15 contributors for this article] (2019). Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction. BioRxiv. ISSN 0362-4331. doi: 10.1101/2019.12.20.869974.
  • Arnesen, Liv Henriette; Haj Yasein, Nadia; Tungen, Jørn Eivind; Södling, Helen; Matthews, Jason & Paulsen, Steinar M [Show all 10 contributors for this article] (2019). Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist. Bioorganic & Medicinal Chemistry. ISSN 0968-0896. 27(18), p. 4059–4068. doi: 10.1016/j.bmc.2019.07.032. Full text in Research Archive
  • Sæther, Thomas; Paulsen, Steinar M; Tungen, Jørn Eivind; Vik, Anders; Aursnes, Marius & Holen, Torgeir [Show all 8 contributors for this article] (2018). Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects. European Journal of Medicinal Chemistry. ISSN 0223-5234. 155, p. 736–753. doi: 10.1016/j.ejmech.2018.06.034. Full text in Research Archive
  • Gomez, Alvin; Bindesbøll, Christian; Somisetty, Venkata Satheesh; Grimaldi, Giulia; Hutin, David & MacPherson, Laura [Show all 14 contributors for this article] (2018). Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity. Biochemical Journal. ISSN 0264-6021. 475(23), p. 3827–3846. doi: 10.1042/BCJ20180347. Full text in Research Archive
  • Haj Yasein, Nadia; Berg, Ole; Jerneren, Fredrik; Refsum, Helga; Nebb, Hilde Irene & Dalen, Knut Tomas (2017). Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1862(6), p. 623–635. doi: 10.1016/j.bbalip.2017.02.009.
  • Fan, Qiong; Nørgaard, Rikke Christine; Bindesbøll, Christian; Lucas, Christin; Dalen, Knut Tomas & Babaie, Eshrat [Show all 10 contributors for this article] (2017). LXR? regulates hepatic ChREBP? activity and lipogenesis upon glucose, but not fructose feeding in mice. Nutrients. ISSN 2072-6643. 9(7). doi: 10.3390/nu9070678.
  • Moldes-Anaya, Angel; Sæther, Thomas; Uhlig, Silvio; Nebb, Hilde Irene; Larsen, Terje & Eilertsen, Hans Christian [Show all 7 contributors for this article] (2017). Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ. Marine Drugs. ISSN 1660-3397. 15(148). doi: 10.3390/md15060148. Full text in Research Archive
  • Bindesbøll, Christian; Tan, Susanna; Bott, Debbie; Cho, Tiffany; Tamblyn, Laura & MacPherson, Laura [Show all 9 contributors for this article] (2016). TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors. Biochemical Journal. ISSN 0264-6021. 473(7), p. 899–910. doi: 10.1042/BJ20151077.
  • Drevinge, Christina; Dalen, Knut Tomas; Mannila, Maria Nastase; Täng, Margareta Scharin; Ståhlman, Marcus & Klevstig, Martina [Show all 30 contributors for this article] (2016). Perilipin 5 is protective in the ischemic heart. International Journal of Cardiology. ISSN 0167-5273. 219, p. 446–454. doi: 10.1016/j.ijcard.2016.06.037.
  • Bindesbøll, Christian; Fan, Qiong; Nørgaard, Rikke Christine; MacPherson, Laura; Ruan, Hai-Bin & Wu, Jing [Show all 13 contributors for this article] (2015). Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S. Journal of Lipid Research. ISSN 0022-2275. 56, p. 771–785. doi: 10.1194/jlr.M049130.
  • Halvorsen, Bente ; Holm, Sverre; Yndestad, Arne; Scholz, Hanne ; Sagen, Ellen Lund & Nebb, Hilde Irene [Show all 9 contributors for this article] (2014). Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 450(4), p. 1525–1530. doi: 10.1016/j.bbrc.2014.07.036.
  • Grønning-Wang, Line Mariann; Bindesbøll, Christian & Nebb, Hilde Irene (2013). The role of liver X receptor in hepatic de novo lipogenesis and cross-talk with insulin and glucose signaling. In Baez, Rodrigo Valenzuela (Eds.), Lipid metabolism. IntechOpen. ISSN 978-953-51-0944-0. p. 61–90. doi: 10.5772/51357.
  • Haj-Yasein, Nadia Nabil; Dalen, Knut Tomas; Berg, Ole; Bastani, Nasser Ezzatkhah; Refsum, Helga & Nebb, Hilde Irene (2013). Low Cysteine Interferes With PPARγ Activity And Reduces Adipocyte Differentiation. The Journal of Inherited Metabolic Disease (JIMD). ISSN 0141-8955. 36. doi: 10.1007/s10545-013-9631-1.
  • Lei, Peng; Baysa, Anton; Nebb, Hilde Irene; Valen, Guro; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2013). Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. Basic Research in Cardiology. ISSN 0300-8428. 108. doi: 10.1007/s00395-012-0323-z.
  • Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene & Dalen, Knut Tomas (2013). Fatty acids regulate perilipin5 in muscle by activating PPARdelta. Journal of Lipid Research. ISSN 0022-2275. 54(7), p. 1949–1963. doi: 10.1194/jlr.M038992.
  • Boergesen, Michael; Pedersen, Thomas Åskov ; Gross, Barbara; van Heeringen, Simon J.; Hagenbeek, Dik & Bindesbøll, Christian [Show all 14 contributors for this article] (2012). Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor alpha in Mouse Liver Reveals Extensive Sharing of Binding Sites. Molecular and Cellular Biology. ISSN 0270-7306. 32(4), p. 852–867. doi: 10.1128/MCB.06175-11.
  • Wang, Yun Yong; Ryg, Una; Dahle, Maria Krudtaa; Steffensen, Knut Rune; Thiemermann, Christoph & Chaudry, Irshad H. [Show all 12 contributors for this article] (2011). Liver X Receptor Protects against Liver Injury in Sepsis Caused by Rodent Cecal Ligation and Puncture. Surgical Infections. ISSN 1096-2964. 12(4), p. 283–289. doi: 10.1089/sur.2010.066.
  • Boergesen, M; Pedersen, T. A.; Gross, B; van Heeringen, S. J.; Hagenbeek, D & Bindesbøll, Christian [Show all 14 contributors for this article] (2011). Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals extensive sharing of binding sites. Molecular and Cellular Biology. ISSN 0270-7306. doi: 10.1128/%E2%80%8BMCB.06175-11.
  • Dahl, Tuva Børresdatter; Haukeland, John Willy; Yndestad, Arne; Ranheim, Trine; Gladhaug, Ivar Prydz & Damås, Jan Kristian [Show all 16 contributors for this article] (2010). Intracellular Nicotinamide Phosphoribosyltransferase Protects against Hepatocyte Apoptosis and Is Down-Regulated in Nonalcoholic Fatty Liver Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 95(6), p. 3039–3047. doi: 10.1210/jc.2009-2148.
  • Holm, Sverre; Voshol, Peter; Gustafsson, Jan Åke & Nebb, Hilde Irene (2010). LXR beta deficient mice have reduced hepatic insulin clearance during hyperinsulinemic euglucemic clamp. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 392(3), p. 436–441. doi: 10.1016/j.bbrc.2010.01.042.
  • Weedon-Fekjær, Mina Susanne; Johnsen, Guro Mørk; Anthonisen, Elin Holter; Sugulle, Meryam; Nebb, Hilde Irene & Duttaroy, Asim K. [Show all 7 contributors for this article] (2010). Expression of Liver X Receptors in Pregnancies Complicated by Preeclampsia. Placenta. ISSN 0143-4004. 31(9), p. 818–824. doi: 10.1016/j.placenta.2010.06.015.
  • Anthonisen, Elin Holter; Berven, Lise; Holm, Sverre; Nygard, M; Nygård, Maria Torvund & Nebb, Hilde Irene [Show all 7 contributors for this article] (2010). Nuclear Receptor Liver X Receptor Is O-GlcNAc-modified in Response to Glucose. Journal of Biological Chemistry. ISSN 0021-9258. 285(3), p. 1607–1615. doi: 10.1074/jbc.M109.082685.
  • Weedon, Mina Susanne; Dalen, Knut Tomas; Solaas, Karianne; Staff, Anne Cathrine; Duttaroy, Asim K. & Nebb, Hilde Irene (2010). Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells. Journal of Lipid Research. ISSN 0022-2275. 51(7), p. 1886–1896. doi: 10.1194/jlr.M004978.
  • Qin, Yan; Dalen, Knut Tomas; Gustafsson, Jan Åke & Nebb, Hilde Irene (2009). Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1791(2), p. 140–147. doi: 10.1016/j.bbalip.2008.12.003.
  • Dalen, Knut Tomas; Dahl, Tuva Børresdatter; Holter, Elin; Arntsen, Borghild M; Londos, C & Sztalryd, C [Show all 7 contributors for this article] (2007). LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1771, p. 210–227. doi: 10.1016/j.bbalip.2006.11.011.
  • Dalen, Knut Tomas; Ulven, Stine Marie; Arntsen, Borghild M; Solaas, Karianne & Nebb, Hilde Irene (2006). PPAR alpha activators and fasting induce the expression of adipose differentiation-related protein in liver. Journal of Lipid Research. ISSN 0022-2275. 47, p. 931–943.
  • Kase, Eili Tranheim; Andersen, Bård; Nebb, Hilde Irene; Rustan, Arild & Thoresen, G. Hege (2006). 22-Hydroxycholesterols regulate lipid metabolism differently than T0901317 in human myotubes. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1761, p. 1515–1522.
  • Tobin, Kari Anne Risan; Harsem, NK; Dalen, Knut Tomas; Staff, AC; Nebb, Hilde Irene & Duttaroy, Asim K. (2006). Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. Journal of Lipid Research. ISSN 0022-2275. 47, p. 815–823.

View all works in Cristin

  • Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin & Vekterud, Kristin [Show all 15 contributors for this article] (2019). LXRα interacts with the glucose-sensing transcription factor ChREBPα to regulate its transcriptional activity.
  • Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ulven, Stine Marie; Lucas, Christin & Bindesbøll, Christian [Show all 11 contributors for this article] (2018). LXRα interacts with the glucose-sensing transcription factor ChREBPα and increases its transcriptional activity.
  • Fan, Qiong; Nørgaard, Rikke Christine; Ulven, Stine Marie; Lucas, Christin; Bindesbøll, Christian & Grønning-Wang, Line Mariann [Show all 8 contributors for this article] (2018). Exploring the functional importance of a transcriptional cholesterol/sugar switch in liver.
  • Nørgaard, Rikke Christine; Fan, Qiong; Lucas, Christin; Grønning-Wang, Line Mariann; Nebb, Hilde Irene & Sæther, Thomas (2017). LXRα interacts with the glucose-sensing transcription factor ChREBPα and increases its transcriptional activity.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar M & Sylte, Ingebrigt [Show all 8 contributors for this article] (2016). Anti-diabetic activity from marine lipids: new anti-diabetic drugs.
  • Bindesbøll, Christian; Tan, Susanna; MacPherson, Laura; Moen, Anders; Anonsen, Jan Haug & Grønning-Wang, Line Mariann [Show all 8 contributors for this article] (2015). TIPARP MONO-ADP-RIBOSYLATES & INCREASES LIVER X RECEPTOR TRANSACTIVATION.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin & Sylte, Ingebrigt [Show all 8 contributors for this article] (2015). Anti-diabetic activity from marine lipids: new anti-diabetic drugs.
  • Dalen, Knut Tomas; Haj-Yasein, Nadia Nabil; Berg, Ole; Refsum, Helga & Nebb, Hilde Irene (2014). Cysteine and adipocyte differentiation.
  • Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene & Dalen, Knut Tomas (2014). Fatty acids regulate perilipin5 in muscle by activating PPARdelta.
  • Sæther, Thomas; Moldes-Anaya, Angel; Norrheim-Larsen, Laila; Larsen, Terje; Paulsen, Steinar M & Nebb, Hilde Irene (2014). Two near identical oxylipins from the diatom Chaetoceros karianus show isoform-specific agonist activity towards human peroxisome proliferator-activated receptors (PPARs).
  • Moldes-Anaya, Angel; Sæther, Thomas; Larsen, Laila Norrheim; Larsen, Terje; Nebb, Hilde Irene & Paulsen, Steinar (2013). Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae.
  • Moldes-Anaya, Angel; Sæther, Thomas; Norrheim-Larsen, Laila; Nebb, Hilde Irene; Larsen, Terje & Paulsen, Steinar (2013). Identifying natural products with agonist or modulatory activity against human nuclear receptors in extracts from cultured marine microalgae.
  • Bindesbøll, Christian; Fan, Qiong; Sæther, Thomas; Dalen, Knut Tomas; Nebb, Hilde Irene & Grønning-Wang, Line Mariann (2013). Nuclear receptors as targets for treatment and prevention of metabolic diseases.
  • Sæther, Thomas; Moldes-Anaya, Angel; Larsen, Laila Norrheim; Larsen, Terje; Paulsen, Steinar & Nebb, Hilde Irene (2013). Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae.
  • Sæther, Thomas; Moldes-Anaya, Angel; Norrheim-Larsen, Laila; Larsen, Terje; Paulsen, Steinar M & Nebb, Hilde Irene (2013). Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae.
  • Holter Anthonisen, Elin; Berven, Lise; Holm, Sverre; Nygård, Maria; Grønning-Wang, Line Mariann & Nebb, Hilde Irene (2011). Nutritional Regulation of LXR Activity in Lipid and Glucose Metabolism.
  • Bindesbøll, Christian; Anhonisen, Elin Holter; Mandrup, Susanne & Nebb, Hilde Irene (2010). Selective regulation of LXR metabolic pathways by SIRT1.
  • Nebb, Hilde Irene (2010). Cysteine and obesity: Searching for cellular mechanism(s).
  • Nebb, Hilde Irene (2010). Realfagenes betydning for basalforskning innen medisin.
  • Nebb, Hilde Irene (2010). Teknologi- og servicesentre for bedrifter som forsker.
  • Nebb, Hilde Irene (2010). On the role of LXRs in glucose and lipid metabolism.
  • Solaas, Karianne; Legry, Vanessa; Retterstøl, Kjetil; Birkeland, Kåre I.; Meirhaeghe, Aline & Nebb, Hilde Irene (2010). Liver X receptor β polymorphisms in type 2 diabetes mellitus and obesity in three cohort studies: HUNT 2 (Norway), MONICA (France) and HELENA (Europe).
  • Anthonisen, Elin Holter; Bindesbøll, Christian; Grønning-Wang, Line Mariann & Nebb, Hilde Irene (2010). Glycosylation of Liver X Receptor - How Does it Influence LXR Activity?
  • Nebb, Hilde Irene (2009). Mangler kunnskaper om kvinnesykdommer. [Newspaper]. Apollon.
  • Grønning-Wang, Line Mariann; Anthonisen, Elin Holter; Holm, Sverre; Berven, Lise & Nebb, Hilde Irene (2009). The nuclear receptor LXR is O-GlcNAc modified in response to glucose.
  • Solaas, Karianne; Legry, Vanessa; Meirhaeghe, Aline; Birkeland, Kåre I. & Nebb, Hilde Irene (2009). Liver X Receptor beta polymorphism in type 2 disbetes mellitus and obesity.
  • Anthonisen, Elin Holter; Grønning-Wang, Line Mariann; Berven, Lise; Holm, Sverre; Nygård, Maria & Nebb, Hilde Irene (2009). The Nuclear Receptor LXR is O-GlcNAc Modified in Response to Glucose.
  • Solaas, Karianne; Legry, Vanessa; Meirhaeghe, Aline; Birkeland, Kåre I. & Nebb, Hilde Irene (2009). Liver X receptor beta polymorphisms in type 2 diabetes mellitus and obesity.
  • Bindesbøll, Christian; Anthonisen, Elin Holter & Nebb, Hilde Irene (2009). Sirtuin1 is selectively recruited to LXR target genes upon ligand stimulation.
  • Solaas, Karianne; Legry, Vanessa; Meirhaeghe, Aline; Birkeland, Kåre I. & Nebb, Hilde Irene (2009). Liver X receptor beta polymorphisms in type 2 diabetes mellitus and obesity.
  • Dalen, Knut Tomas; Londos, C & Nebb, Hilde Irene (2009). PAT proteins and their function on intracellular lipid droplets.
  • Solaas, Karianne; Legry, Vanessa; Meirhaeghe, Aline; Birkeland, Kåre I. & Nebb, Hilde Irene (2009). Liver X receptor beta polymorphisms in type 2 diabetes mellitus and obesity.
  • Solaas, Karianne; Legry, Vanessa; Meirhaeghe, Aline; Birkeland, Kåre I. & Nebb, Hilde Irene (2009). Liver X receptor beta polymorphisms in type 2 diabetes mellitus and obesity.
  • Bindesbøll, Christian; Anthonisen, Elin Holter & Nebb, Hilde Irene (2009). Posttranslational modifications of LXR during fasting abd refeeding.
  • Bindesbøll, Christian; Anthonisen, Elin Holter & Nebb, Hilde Irene (2009). Both LXRalpha and LXRbeta bind to and activate lipogenic genes in liver.
  • Anthonisen, Elin Holter; Holm, Sverre; Berven, Lise; Nygård, Maria; Nebb, Hilde Irene & Grønning-Wang, Line Mariann (2009). The Nuclear Receptor LXR is O-GlcNAc Modified in Response to Glucose.
  • Bindesbøll, Christian; Anthonisen, Elin Holter; Steffensen, Knut Rune; Mandrup, Susanne; Gustafsson, Jan-Åke & Nebb, Hilde Irene (2009). Both LXRalpha and LXRbeta bind to SREBP-1c in liver.
  • Anthonisen, Elin Holter; Grønning-Wang, Line Mariann; Berven, Lise; Holm, Sverre; Nygård, Maria & Nebb, Hilde Irene (2009). The Nuclear Receptor LXR is O-GlcNAc Modified in Response to Glucose.
  • Solaas, Karianne; Legry, Vanesssa; Holven, Kirsten Bjørklund; Retterstøl, Kjetil; Thorsby, Per Medbøe & Ferrieres, J [Show all 13 contributors for this article] (2009). Association study between LXRbeta polymorphisms and type 2 diabetes mellitus.
  • Weedon-Fekjaer, MS; Johnsen, Guro Mørk; Sugulle, Meryam; Duttaroy, Asim K.; Nebb, Hilde Irene & Staff, Anne Cathrine (2008). Regulation of liver X receptor and target genes in primary trophoblasts, placenta, dfcidua and fat tissue. Placenta. ISSN 0143-4004. 29, p. A44–A44.
  • Nebb, Hilde Irene (2008). LXRs in glucose and lipid metabolism - an overview.
  • Nebb, Hilde Irene (2008). LXr and lipid metabolism.
  • Nebb, Hilde Irene (2008). LXR as a glucose sensor?
  • Nebb, Hilde Irene (2008). LXR and circadian regulation.
  • Nebb, Hilde Irene (2008). An update- NRs in glucose and lipid metabolism, health and disease during aging.
  • Nebb, Hilde Irene (2008). Lipid activated nuclear receptors.
  • Nebb, Hilde Irene (2008). LXRs and glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). LXR as an insulin and glucose sensor in liver.
  • Nebb, Hilde Irene (2007). On the role of LXRs in controlling the lipid and glucose homeostasis.
  • Nebb, Hilde Irene (2007). On the role of LXRs in glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). On the role of LXRs in glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). LXR as an insulin sensor in liver and adipose tissue.
  • Nebb, Hilde Irene (2007). Aging and disease: Glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). Aging and disease: Glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). Aging and disease: Glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). LXRbeta plays an important role in high fat diet-induced insulin resistance.
  • Nebb, Hilde Irene (2007). LXR IN AGEINGControl of glucose and lipid metabolism.
  • Nebb, Hilde Irene (2007). Regulation of Fatty acid Elongase 6 by the Nuclear Receptor LXR.
  • Nebb, Hilde Irene (2006). Månedens forsker-Forsker på budbringerne i cellene våre. [Internet]. Internet.
  • Tobin, Kari Anne Risan; Johnsen, Guro Mørk; Harsem, NK; Nebb, Hilde Irene; Staff, AC & Duttaroy, Asim K. (2006). Stimulation of fatty acid uptake in human placental choriocarcinoma (BeWo) cells by polyunsaturated fatty acids. Chemistry and Physics of Lipids. ISSN 0009-3084. 143, p. 79–79.
  • Nebb, Hilde Irene (2006). Aging and disease:Glucose and lipid metabolism, circadian regulation.
  • Nebb, Hilde Irene (2006). LXR in metabolic control.
  • Nebb, Hilde Irene (2006). Aging and disease:Glucose and lipid metabolism.
  • Nebb, Hilde Irene (2006). LXR in aging and disease: Glucose and lipid metabolism.
  • Nebb, Hilde Irene (2006). LXR in metabolic control.
  • Høydalen, Anne; Nebb, Hilde Irene & Iversen, Per Ole (2008). Nuclear Receptors In Malignant B Lymphocytes. Universitet i Oslo.
  • Bindesbøll, Christian & Nebb, Hilde Irene (2008). LXRα in the ageing processControl of hepatic glucose and lipid metabolism. Universitet i Oslo.
  • Cathrine, Strandskogen & Nebb, Hilde Irene (2008). LSDP5The role of lipid storage droplet protein 5 in liver of diet induced obesity and insulin resistant mice. Universitet i Oslo.
  • Nebb, Hilde Irene (2007). Transcriptional regulation of the LSDP5 gene. Universitet i Oslo.
  • Nebb, Hilde Irene (2006). The lipid storage droplet binding proteins, LSDP5 and ADFP. Borghild Arntsen Universitet i Oslo.

View all works in Cristin

Published Apr. 13, 2011 2:34 PM - Last modified Nov. 8, 2019 3:07 PM