Latest publications from the Faculty of Medicine

• Andresen, Kristoffer; Klæboe, Lars Gunnar; Lie, Øyvind Haugen; Broch, Kaspar; Kvaslerud, Anette Borger & Bosse, Gerhard [Show all 10 contributors for this article] (2024). No adverse association between exercise exposure and diffuse myocardial fibrosis in male endurance athletes. Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-57233-5.
• Nilsbakken, I.M.W.; Wisborg, Torben; Sollid, Stephen J. M. & Jeppesen, Elisabeth (2024). Functional outcome and associations with prehospital time and urban-remote disparities in trauma: A Norwegian national population-based study. Injury. ISSN 0020-1383. doi: 10.1016/j.injury.2024.111459.
• Haugen, Morten; Magnussen, Karin; Aarsland, Tonje Eiane; Nissen-Meyer, Lise Sofie Haug & Strand, Tor Arne (2024). The effect of donation frequency on donor health in blood donors donating plasma by plasmapheresis: study protocol for a randomized controlled trial. Trials. ISSN 1745-6215. 25(1). doi: 10.1186/s13063-024-08035-7.
• Stenmarck, Mille Sofie; Whitehurst, David GT.; Baker, Rachel & Barra, Mathias (2024). Charting public views on the meaning of illness severity. Social Science and Medicine. ISSN 0277-9536. 347. doi: 10.1016/j.socscimed.2024.116760.
• Sæther, Linn Sofie; Szabo, Attila; Akkouh, Ibrahim Ahmed; Haatveit, Beathe ; Mohn, Christine & Vaskinn, Anja [Show all 14 contributors for this article] (2024). Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain. Brain, Behavior, and Immunity. ISSN 0889-1591. 118, p. 287–299. doi: 10.1016/j.bbi.2024.03.014.
• Klæboe, Lars Gunnar; Lie, Øyvind Haugen; Brekke, Pål Haugar; Bosse, Gerhard; Hopp, Einar & Haugaa, Kristina Ingrid Helena Hermann [Show all 7 contributors for this article] (2024). Differentiation of Myocardial Properties in Physiological Athletic Cardiac Remodeling and Mild Hypertrophic Cardiomyopathy. Biomedicines. 12(2). doi: 10.3390/biomedicines12020420.
• Wang, He-Ling; Siow, Richard; Schmauck-Medina, Tomas; Zhang, Jianying; Sandset, Per Morten & Filshie, Clare [Show all 38 contributors for this article] (2024). Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1079-5006. 79(4). doi: 10.1093/gerona/glae029.
• Fredheim, Olav Magnus Søndenå; Torvund, Solveig Kristine Kolstad; Thoresen, Lisbeth & Magelssen, Morten (2024). How should respiratory depression and loss of airway patency be handled during initiation of palliative sedation? Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. doi: 10.1111/aas.14396.
• Subbotina, Anna; Skjølsvik, Eystein; Solbu, Marit Dahl; Miroslawska, Atena & Steigen, Terje Kristian (2024). Echocardiographic findings following renal sympathetic denervation for treatment resistant hypertension, the ReShape CV-risk study. Blood Pressure. ISSN 0803-7051. 33(1). doi: 10.1080/08037051.2024.2326298.
• Larsen, Johanne Hartwedt; Andersen, Svend; Perminow, Gøri Margrete; Mundal, Håkon Stangeland; Mårild, Karl Staffan & Stabell, Niklas [Show all 7 contributors for this article] (2024). Higher incidence of paediatric inflammatory bowel disease by increasing latitude in Norway, but stable incidence by age. Acta Paediatrica. ISSN 0803-5253. doi: 10.1111/apa.17222.
• Wu, Chenyu; Gunnarsson, Einar Bjarki; Myklebust, Even Moa; Luque, Alvaro Kohn; Tadele, Dagim Shiferaw & Enserink, Jorrit [Show all 9 contributors for this article] (2024). Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data. PLoS Computational Biology. ISSN 1553-734X. 20(3). doi: 10.1371/journal.pcbi.1011888.
• Damås, Jan Kristian; Otterdal, Kari; Astrup, Elisabeth; Lekva, Tove; Janardhanan, Jeshina & Michelsen, Annika Elisabet [Show all 9 contributors for this article] (2024). Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome. Infection. ISSN 0300-8126. doi: 10.1007/s15010-024-02192-2.
• Moshina, Nataliia; Gräwingholt, Axel; Lång, Kristina; Mann, Ritse; Hovda, Tone & Hoff, Solveig Kristin Roth [Show all 11 contributors for this article] (2024). Digital breast tomosynthesis in mammographic screening: false negative cancer cases in the To-Be 1 trial. Insight into Imaging. ISSN 1869-4101. 15(1). doi: 10.1186/s13244-023-01604-5.
• Netteland, Dag Ferner; Aarhus, Mads; Sandset, Else Charlotte; Padayachy, Llewellyn; Helseth, Eirik & Brekken, Reidar (2024). Noninvasive Assessment of Intracranial Pressure: Deformability Index as an Adjunct to Optic Nerve Sheath Diameter to Increase Diagnostic Ability. Neurocritical Care. ISSN 1541-6933. doi: 10.1007/s12028-024-01955-x.
• Alnaqbi, Khalid A.; Al Adhoubi, Nasra; Aldallal, Sara; Al Emadi, Samar; Al-Herz, Adeeba & El Shamy, Amin M. [Show all 10 contributors for this article] (2024). Consensus-Based Overarching Principles and Recommendations on the Use of Biosimilars in the Treatment of Inflammatory Arthritis in the Gulf Region. BioDrugs. ISSN 1173-8804. doi: 10.1007/s40259-023-00642-1.
• Skaug, Kristina Lindquist; Engh, Anna Marie Ellström & Bø, Kari (2024). Pelvic floor muscle training in female functional fitness exercisers: An assessor-blinded randomised controlled trial . British Journal of Sports Medicine. ISSN 0306-3674. p. 1–8. doi: 10.1136/bjsports-2023-107365.
• Carlsen, Monica H.; Totland, Torunn Holm; Kumar, Radhika; Lensnes, Therese M.L.; Sharma, Archana & Suntharalingam, A. Anita [Show all 9 contributors for this article] (2024). Evaluation of a digital FFQ using 24 h recalls as reference method, for assessment of habitual diet in women with South Asian origin in Norway. Public Health Nutrition (PHN). ISSN 1368-9800. 27(1), p. 1–11. doi: 10.1017/S1368980024000302. Full text in Research Archive
• Kwakye, Benjamin Danso; Li, Yongjun; Mohamed, Halima Habuba; Baidoo, Evans & Asenso, Theophilus Quachie (2024). Particle guided metaheuristic algorithm for global optimization and feature selection problems[Formula presented]. Expert Systems With Applications. ISSN 0957-4174. 248. doi: 10.1016/j.eswa.2024.123362.
• Faiz, Kashif Waqar & Hem, Erlend (2024). Lukket inne-syndrom. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 144(1), p. 1–4. doi: 10.4045/tidsskr.23.0184.
• Mahootiha, Maryamalsadat; Qadir, Hemin Ali; Aghayan, Davit; Fretland, Åsmund Avdem; Edwin, Bjørn von Gohren & Balasingham, Ilangko (2024). Deep learning-assisted survival prognosis in renal cancer: A CT scan-based personalized approach. Heliyon. ISSN 2405-8440. 10(2). doi: 10.1016/j.heliyon.2024.e24374.
• Staff, Annetine (2024). Covid-19 i graviditet - risiko for mor og barn. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 144(1), p. 1–3. doi: 10.4045/tidsskr.23.0847.
• Juul, Frederik Emil; Cross, Amanda J.; Schoen, Robert E.; Senore, Carlo; Pinsky, Paul F. & Miller, Eric A. [Show all 17 contributors for this article] (2024). Effectiveness of Colonoscopy Screening vs Sigmoidoscopy Screening in Colorectal Cancer. JAMA Network Open. ISSN 2574-3805. 7(2). doi: 10.1001/jamanetworkopen.2024.0007. Show summary

  Importance: Randomized clinical screening trials have shown that sigmoidoscopy screening reduces colorectal cancer (CRC) incidence and mortality. Colonoscopy has largely replaced sigmoidoscopy for CRC screening, but long-term results from randomized trials on colonoscopy screening are still lacking. Objective: To estimate the additional screening benefit of colonoscopy compared with sigmoidoscopy. Design, setting, and participants: This comparative effectiveness simulation study pooled data on 358 204 men and women randomly assigned to sigmoidoscopy screening or usual care in 4 randomized sigmoidoscopy screening trials conducted in Norway, Italy, the US, and UK with inclusion periods in the years 1993 to 2001. The primary analysis of the study was conducted from January 19 to December 30, 2021. Intervention: Invitation to endoscopic screening. Main outcomes and measures: Primary outcomes were CRC incidence and mortality. Using pooled 15-year follow-up data, colonoscopy screening effectiveness was estimated assuming that the efficacy of colonoscopy in the proximal colon was similar to that observed in the distal colon in the sigmoidoscopy screening trials. The simulation model was validated using data from Norwegian participants in a colonoscopy screening trial. Results: This analysis included 358 204 individuals (181 971 women [51%]) aged 55 to 64 years at inclusion with a median follow-up time ranging from 15 to 17 years. Compared with usual care, colonoscopy prevented an estimated 50 (95% CI, 42-58) CRC cases per 100 000 person-years, corresponding to 30% incidence reduction (rate ratio, 0.70 [95% CI, 0.66-0.75]), and prevented an estimated 15 (95% CI, 11-19) CRC deaths per 100 000 person-years, corresponding to 32% mortality reduction (rate ratio, 0.68 [95% CI, 0.61-0.76]). The additional benefit of colonoscopy screening compared with sigmoidoscopy was 12 (95% CI, 10-14) fewer CRC cases and 4 (95% CI, 3-5) fewer CRC deaths per 100 000 person-years, corresponding to percentage point reductions of 6.9 (95% CI, 6.0-7.9) for CRC incidence and 7.6 (95% CI, 5.7-9.6) for CRC mortality. The number needed to switch from sigmoidoscopy to colonoscopy screening was 560 (95% CI, 486-661) to prevent 1 CRC case and 1611 (95% CI, 1275-2188) to prevent 1 CRC death. Conclusions and relevance: The findings of this comparative effectiveness study assessing long-term follow-up after CRC screening suggest that there was an additional preventive effect on CRC incidence and mortality associated with colonoscopy screening compared with sigmoidoscopy screening, but the additional preventive effect was less than what was achieved by introducing sigmoidoscopy screening where no screening existed. The results probably represent the upper limit of what may be achieved with colonoscopy screening compared with sigmoidoscopy screening.

• Kennedy, Keith E.; de Rosbo, Nicole Kerlero; Uccelli, Antonio; Cellerino, Maria; Ivaldi, Federico & Contini, Paola [Show all 37 contributors for this article] (2024). Multiscale networks in multiple sclerosis. PLoS Computational Biology. ISSN 1553-734X. 20(2). doi: 10.1371/journal.pcbi.1010980.
• Corrales, Jeanne; Ramos Alonso, Lucia; González-Sabín, Javier; Ríos-Lombardía, Nicolás; Trevijano-Contador, Nuria & Berg, Henriette Engen [Show all 12 contributors for this article] (2024). Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole. Microbiology spectrum. ISSN 2165-0497. 12(2). doi: 10.1128/spectrum.02594-23.
• Lashkarivand, Aslan; Ringstad, Geir & Wiedmann, Markus (2024). Empowering early career vascular neurosurgeons in the endovascular Era: Managing intraoperative aneurysm rupture through a systematic algorithmic approach. Journal of clinical neuroscience. ISSN 0967-5868. 120, p. 229–231. doi: 10.1016/j.jocn.2024.01.006.
• Fjeldstad, Heidi; Jacobsen, Daniel Pitz; Johnsen, Guro Mørk; Sugulle, Meryam; Chae, Angel & Kanaan, Sami B. [Show all 8 contributors for this article] (2024). Fetal-origin cells in maternal circulation correlate with placental dysfunction, fetal sex, and severe hypertension during pregnancy. Journal of Reproductive Immunology. ISSN 0165-0378. 162. doi: 10.1016/j.jri.2024.104206.
• Nordsteien Svensøy, Johannes; Alonso, Erik; Elola, Andoni; Bjørnerheim, Reidar; Ræder, Johan & Aramendi, Elisabete [Show all 7 contributors for this article] (2024). Cardiac output estimation using ballistocardiography: a feasibility study in healthy subjects. Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-52300-3.
• Färdig, Martin; Hoyer, Angela; Almqvist, Catarina; Bains, Karen Eline Stensby; Carlsen, Karin Cecilie Lødrup & Gudmundsdottir, Hrefna Katrin [Show all 18 contributors for this article] (2024). Infant lung function and early skin barrier impairment in the development of asthma at age 3 years. Allergy. European Journal of Allergy and Clinical Immunology. ISSN 0105-4538. doi: 10.1111/all.16024.
• Fleischer, Vinzenz; Gonzalez-Escamilla, Gabriel; Pareto, Deborah; Rovira, Alex; Sastre-Garriga, Jaume & Sowa, Piotr [Show all 23 contributors for this article] (2024). Prognostic value of single-subject grey matter networks in early multiple sclerosis. Brain. ISSN 0006-8950. 147(1), p. 135–146. doi: 10.1093/brain/awad288.
• Sahli, Sarah & Størdal, Ketil (2024). Systematic review of socioeconomic factors and COVID-19 in children and adolescents. Acta Paediatrica. ISSN 0803-5253. doi: 10.1111/apa.17091.
• Risløkken, Jeanette; Macedo, Marthe Dalevoll; Bø, Kari; Engh, Anna Marie Ellström & Siafarikas, Franziska (2024). The severity of second-degree perineal tears and perineal pain during three months postpartum: A prospective cohort study. Midwifery. ISSN 0266-6138. 131. doi: 10.1016/j.midw.2024.103930. Full text in Research Archive
• Sandvik, Reidun Karin Norheim Myhre; Husebø, Bettina Elisabeth Franziska; Selbæk, Geir; Strand, Gunhild Vesterhus; Patrascu, Monica & Mustafa, Manal [Show all 7 contributors for this article] (2024). Oral symptoms in dying nursing home patients. Results from the prospective REDIC study. BMC Oral Health. ISSN 1472-6831. 24(1). doi: 10.1186/s12903-024-03901-x. Full text in Research Archive
• Lam, Yin Ting; Papon, Jean-François; Alexandru, Mihaela; Anagiotos, Andreas; Armengot, Miguel & Boon, Mieke [Show all 30 contributors for this article] (2023). Lack of Correlation of Sinonasal and Otologic Reported Symptoms With Objective Measurements Among Patients With Primary Ciliary Dyskinesia: An International Study. Clinical and Experimental Otorhinolaryngology. ISSN 1976-8710. 16(4), p. 407–412. doi: 10.21053/ceo.2023.01130.
• Kagaigai, Alphoncina; Mori, Amani Thomas; Anaeli, Amani & Grepperud, Sverre Ole (2023). Whether or not to enroll, and stay enrolled? A Tanzanian cross-sectional study on voluntary health insurance. Health Policy OPEN. ISSN 2590-2296. 4(20). doi: 10.1016/j.hpopen.2023.100097.

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• Gløersen, Marthe; Steen Pettersen, Pernille; Maugesten, Øystein Gunnar; Mulrooney, Elisabeth; Mathiessen, Alexander & Gammelsrud, Heidi [Show all 14 contributors for this article] (2024). Corrigendum to “Study protocol for the follow-up examination of the Nor-Hand study: A hospital-based observational cohort study exploring pain and biomarkers in people with hand osteoarthritis” [Osteoarthr. Cartil. Open 3 (2021) 100198] (Osteoarthritis and Cartilage Open (2021) 3(3), (S2665913121000613), (10.1016/j.ocarto.2021.100198)). Osteoarthritis and Cartilage Open. ISSN 2665-9131. 6(1). doi: 10.1016/j.ocarto.2022.100274.
• Hansen, Ellen-Sofie; Edvardsen, Magnus; Aukrust, Pål; Ueland, Thor; Hansen, John Bjarne & Brækkan, Sigrid Kufaas [Show all 7 contributors for this article] (2024). Galectin-3-binding protein and future venous thromboembolism. Research and Practice in Thrombosis and Haemostasis (RPTH). ISSN 2475-0379. 8(1). doi: 10.1016/j.rpth.2023.102311.
• Alexandrov, Ludmil B.; Kim, Jaegil; Haradhvala, Nicholas J.; Huang, Mi Ni; Tian Ng, Alvin Wei & Wu, Yang [Show all 1,383 contributors for this article] (2023). Author Correction: The repertoire of mutational signatures in human cancer (Nature, (2020), 578, 7793, (94-101), 10.1038/s41586-020-1943-3). Nature. ISSN 0028-0836. 614(7948). doi: 10.1038/s41586-022-05600-5.
• Wu, Chelsea Q.; Cowan, Frances M.; Jary, Sally; Thoresen, Marianne; Chakkarapani, Ela & Spencer, Arthur P. C. (2023). Author Correction: Cerebellar growth, volume and diffusivity in children cooled for neonatal encephalopathy without cerebral palsy (Scientific Reports, (2023), 13, 1, (14869), 10.1038/s41598-023-41838-3). Scientific Reports. ISSN 2045-2322. 13(1). doi: 10.1038/s41598-023-49211-0.
• Uleberg, Oddvar; Majeed, Waleed Mohammed; Hoås, Einar Frigstad & Røise, Olav (2023). Compliance to national trauma triage criteria in Norway - a cross-sectional study.
• Yuan, Yuan; Ju, Young Seok; Kim, Youngwook; Li, Jun; Wang, Yumeng & Yoon, Christopher J. [Show all 1,340 contributors for this article] (2023). Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x). Nature Genetics. ISSN 1061-4036. 55(5). doi: 10.1038/s41588-020-0629-y.
• Melokhina, Valeriia; Paulshus Sundlisæter, Nina; Sexton, Joseph; Sundin, Ulf Gunnar; Aga, Anna-Birgitte & Kjørholt, Kaja Eriksrud [Show all 10 contributors for this article] (2023). Subclinical inflammation and joint damage progression in patients with early RA fulfilling 2011 vs 2022 ACR/EULAR Boolean remission criteria: Data from the ARCTIC study. Annals of the Rheumatic Diseases. ISSN 0003-4967. doi: 10.1136/ard-2023-224950.
• Fiskå, Bendik Seth; Pay, Aase Serine Devold; Staff, Anne Cathrine & Sugulle, Meryam (2023). Correction: Gestational diabetes mellitus, follow-up of future maternal risk of cardiovascular disease and the use of eHealth technologies – a scoping review (Systematic Reviews, (2023), 12, 1, (178), 10.1186/s13643-023-02343-w). Systematic Reviews. ISSN 2046-4053. 12(1). doi: 10.1186/s13643-023-02383-2.
• Giustina, Andrea; di Filippo, Luigi; Facciorusso, Antonio; Adler, Robert A.; Binkley, Neil & Bollerslev, Jens [Show all 29 contributors for this article] (2023). Correction: Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta‑analysis (Reviews in Endocrine and Metabolic Disorders, (2023), 10.1007/s11154-023-09837-x). Reviews in endocrine and metabolic disorders (Print). ISSN 1389-9155. doi: 10.1007/s11154-023-09837-x.
• Wikerøy, Annette Konstanse Bordewich; Jakobsen, Rune Bruhn; Fuglesang, Hendrik Frølich & Randsborg, Per-Henrik (2023). Tittel Intramedullær nagling versus Platefiksasjon av dislokerte 3 og 4 parts proksimale humerusfrakturer, en single senter randomisert kontrollert studie. .
• Salte, Ivar Mjåland; Østvik, Andreas; Olaisen, Sindre Hellum; Karlsen, Sigve; Dahlslett, Thomas & Smistad, Erik [Show all 13 contributors for this article] (2023). Response to “Minimal Detectable Change and Reproducibility of Echocardiographic Strain: Implications for Clinical Practice”. Journal of the American Society of Echocardiography. ISSN 0894-7317. doi: 10.1016/j.echo.2023.08.017.
• Wang, Daoping; Bjørnstad, Ottar Nordal; Lei, Tianyang; Sun, Yida; Huo, Jingwen & Hao, Qi [Show all 12 contributors for this article] (2023). Author Correction: Supply chains create global benefits from improved vaccine accessibility (Nature Communications, (2023), 14, 1, (1569), 10.1038/s41467-023-37075-x). Nature Communications. ISSN 2041-1723. 14(1). doi: 10.1038/s41467-023-41336-0.
• Feiring, Eli; Løberg, Magnus; Bjaalie, Jan G.; Dyb, Grete Anita & Harbo, Hanne-Cathrin Flinstad (2023). Kjønn og helse, utdanning og forskning. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(11). doi: 10.4045/tidsskr.23.0408.
• Smiseth, Otto Armin (2023). Trouble with estimating filling pressure in acute heart failure: lessons from Takotsubo syndrome. European Heart Journal-Cardiovascular Imaging. ISSN 2047-2404. 24(6), p. 708–709. doi: 10.1093/ehjci/jead082.
• Gråbø, Helene; Garborg, Kjetil Kjeldstad & Reigstad, Hallvard (2023). Forebygger probiotika nekrotiserende enterokolitt hos ekstremt premature? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(4). doi: 10.4045/tidsskr.22.0544.
• Davidson, Ben; Doutel, Delfim; Holth, Arild & Nymoen, Dag Andre (2023). Correction to: Claudin-10 is a new candidate prognostic marker in metastatic high-grade serous carcinoma (Virchows Archiv, (2023), 10.1007/s00428-023-03541-6). Virchows Archiv. ISSN 0945-6317. doi: 10.1007/s00428-023-03567-w.

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