Fekadu Abebe

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Academic interests

  • Infectious diseases epidemiology and control
  • Infection and immunity, including vaccines and vaccinations, and immunodiagnosis
  • Neglected tropical diseases
  • Global Health 

Courses taught

Background

  • PhD in immunology, Faculty of Medicine, University of Oslo (2002)
  • MSc, Microbiology/parasitology, Faculty of Natural Sceinces, Addis Abeba University (1993)

Positions held

  • Senior scientist, University of Oslo, 2018 - present
  • Scientist, University of Oslo, 2007-2018
  • Postodctoral fellow, University of Oslo, 2005-2007
  • PhD fellow, University of Oslo, 1997-2002
  • Head, Schistosomiasis Unit, 1987-1991
  • Lecturer and researcher, Addis Abeba University, 1983-1996

Committees served

  • Member, Tuberculosis Vaccine Initiative, 2012- present.
  • Member, Network of NGOs for Neglected Tropical Diseases. 2017-present. 
  • Associate editor (editorial board member), BMC Public Health, 2009-2017.
  • Special issue editor (editorial board member), OMICS – Immunomycobacteriology ( Journal of Mycobacterial Diseases), 2009-2017.
  • Member, Stop TB, New diagnostics Working Group (NDWG), 2010 - present
  • Chairman, Laboratory and Animal House Management Committee, Aklilu Lemma Institute of Pathobiology, Addis Abeba University, 1993-1996
  • Secretary, Inter-institutional Collaboration Committee (CIC) for the control of Tropical diseases in Ethiopia, 1990-1996
  • Secretary, Research and Publications of Committee of Aklilu Lemma Institute of Pathobiology, Addis Abeba University, 1989-1996
Tags: Global South

Publications

  • Abebe, Fekadu (2020). Immunological basis of early clearance of Mycobacterium tuberculosis infection: the role of natural killer cells. Clinical and Experimental Immunology. ISSN 0009-9104. 0, p. 1–9. doi: 10.1111/cei.13565.
  • Ahmed, Seid Mussa; Sundby, Johanne; Aragaw, Yesuf Ahmed & Abebe, Fekadu (2020). : Self-medication and safety profile of medicines used among pregnant women in a tertiary teaching hospital in Jimma, Ethiopia: a cross-sectional study. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. doi: 10.3390/ijerph17113993.
  • Abebe, Fekadu (2019). Synergy between Th1 and Th2 responses during Mycobacterium tuberculosis infection: a review of current understanding. International Reviews of Immunology. ISSN 0883-0185. 38(4), p. 172–179. doi: 10.1080/08830185.2019.1632842.
  • Sima, Bezawit Temesgen; Belachew, Tefera; Bjune, Gunnar Aksel & Abebe, Fekadu (2019). Traditional healers`role in the detection of active tuberculosis cases in a pastoralist community in Ethiopia: a pilot intervention study. BMC Public Health. ISSN 1471-2458. 19(1). doi: 10.1186/s12889-019-7074-9. Full text in Research Archive
  • Sima, Bezawit Temesgen; Belachew, Tefera & Abebe, Fekadu (2019). Health care providers knowledge, attitude and perceived stigma regarding tuberculosis in a pastoralist community in Ethiopia: A Cross-sectional Study . BMC Health Services Research. ISSN 1472-6963. 19(19), p. 3815–3821. doi: 10.1186/s12913-018-3815-1. Full text in Research Archive
  • Abebe, Fekadu; Belay, Mulugeta; Legesse, Mengistu; Franken, Kees LMC & Ottenhoff, Tom HM (2018). IgA and IgG against Mycobacterium tuberculosis Rv2031 discriminate between pulmonary tuberculosis patients, Mycobacterium tuberculosis-infected and non-infected individuals. PLOS ONE. ISSN 1932-6203. 13(1), p. 1–19. doi: 10.1371/journal.pone.0190989. Full text in Research Archive
  • Sima, Bezawit Temesgen; Belachew, Tefera & Abebe, Fekadu (2017). Knowledge, attitude and perceived stigma towards tuberculosis among pastoralists; Do they differ from sedentary communities? A comparative cross-sectional study. PLOS ONE. ISSN 1932-6203. 12(7), p. 1–17. doi: 10.1371/journal.pone.0181032. Full text in Research Archive
  • Abebe, Fekadu; Mengesha, Mulugeta Belay & Legesse, Mengistu (2017). IFN-γ against the 38-kDa antigen of Mycobacterium tuberculosis discriminates pulmonary tuberculosis from infection, and infection from exposure: evidence from a study of human population in a high endemic setting. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 126(2), p. 135–142. doi: 10.1111/apm.12793.
  • Abebe, Fekadu; Belay, Mulugeta; Legesse, Mengistu; Mihret, Adane & Franken, Kees L (2017). Association of ESAT-6/CFP-10 induced IFN-gamma, TNF-alpha, IL-10 with clinical tuberculosis: evidence from cohorts of pulmonary tuberculosis patients, household contacts, and community controls in an endemic setting. Clinical and Experimental Immunology. ISSN 0009-9104. 189(2), p. 241–249. doi: 10.1111/cei.12972. Full text in Research Archive
  • Mengesha, Mulugeta Belay; Legesse, Mengistu; Ottenhoff, Tom H.M.; Mihret, Adane; Franken, Kees L & Bjune, Gunnar Aksel [Show all 7 contributors for this article] (2016). IFN-γ and IgA against non-methylated heparin-binding hemagglutinin as markers of protective immunity and latent tuberculosis: Results of a longitudinal study from an endemic setting. Journal of Infection. ISSN 0163-4453. 72(2), p. 189–200. doi: 10.1016/j.jinf.2015.09.040.
  • Mengesha, Mulugeta Belay; Bjune, Gunnar Aksel & Abebe, Fekadu (2015). Prevalence of tuberculosis, HIV, and TB-HIV co-infection among pulmonary tuberculosis suspects in a predominantly pastoralist area, northeast Ethiopia. Global health action. ISSN 1654-9716. 8:27949(1), p. 1–8. doi: 10.3402/gha.v8.27949.
  • Mengesha, Mulugeta Belay; Bjune, Gunnar Aksel & Abebe, Fekadu (2015). Tuberculosis and HIV infection among pulmonary tuberculosis suspects in a predominantly pastoralist area, Northeast Ethiopia. Global health action. ISSN 1654-9716. 8(27949), p. 1–7. doi: 10.3402/gha.v8.27949. Full text in Research Archive
  • Mengesha, Mulugeta Belay; Legesse, Mengistu; Mihret, Adane; Bekele, Yonas; Bjune, Gunnar Aksel & Abebe, Fekadu (2015). Lipoarabinomannan-specific TNF-alpha and IFN-gamma as markers of protective immunity against tuberculosis: a cohort study in an endemic setting. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 123(10), p. 851–857. doi: 10.1111/apm.12423.
  • Mengesha, Mulugeta Belay; Legesse, Mengistu; Mihret, Adane; Ottenhoff, Tom HM; Franken, Kees Lumc & Bjune, Gunnar Aksel [Show all 7 contributors for this article] (2015). Pro-and-anti-inflammatory cytokines against Rv2031 are elevated during latent tuberculosis: a study in cohorts of tuberculosis patients, household contacts and community Controls in an endemic setting. PLOS ONE. ISSN 1932-6203. p. 1–13. doi: 10.1371/journal.pone.0124134. Full text in Research Archive
  • Belay, Mulugeta ; Dagne, Daniel; Legesse, Mengistu; Mihret, Adane; Bekele, Yonas & Medhin, Girmay [Show all 8 contributors for this article] (2014). QuantiFERON-TB-Gold In-Tube test conversions and reversions among Tuberculosis patients and their household contacts in Addis Ababa: a one year follow-up study. BMC Infectious Diseases. ISSN 1471-2334. 14:654. doi: 10.1186/s12879-014-0654-5.
  • Abebe, Fekadu (2014). The role of T cells in mucosal immunity against Mycobacterium tuberculosis (Mtb) infection: a review of current understanding. Journal of Clinical & Cellular Immunology. ISSN 2155-9899. doi: 10.4172/2155-9899.1000254.
  • Belay, Mulugeta ; Ameni, Gobena; Bjune, Gunnar Aksel; Couvin, David; Rastogi, Nalin & Abebe, Fekadu (2014). Strain diversity of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Afar pastoral Region of Ethiopia. BioMed Research International. ISSN 2314-6133. 2014. doi: 10.1155/2014/238532.
  • Dadi, Mengistu Legesse; Ameni, Gobena; Medhin, Girmay; Franken, Kees LMC; Kassa, Gezahegne Mamo & Ottenhoff, Tom HM [Show all 8 contributors for this article] (2013). IgA response to ESAT-6/CFP-10 and Rv2031 antigens varies in culture-confirmed pulmonary tuberculosis patients, healthy Mycobacterium tuberculosis infected and non-infected individuals in a tuberculosis endemic setting, Ethiopia". Scandinavian Journal of Immunology. ISSN 0300-9475. 78(3), p. 266–274. doi: 10.1111/sji.12080.
  • Mengesha, Mulugeta Belay; Bjune, Gunnar Aksel; Ameni, Gobena & Abebe, Fekadu (2012). Diagnostic and treatment delay among tuberculosis patients in Afar Region, Ethiopia: a cross-sectional study. BMC Public Health. ISSN 1471-2458. 12. doi: 10.1186/1471-2458-12-369.
  • Abebe, Fekadu (2012). Is interferon-gamma (IFN-g) the right marker for BCG-induced immune protection? the missing link in our understanding of tuberculosis immunology. Clinical and Experimental Immunology. ISSN 0009-9104. 169(3), p. 213–219. doi: 10.1111/j.1365-2249.2012.04614.x.
  • Kassa, Gezahegne Mamo; Abebe, Fekadu; Worku, Yalelet; Legesse, Mengistu; Medhin, Girmay & Bjune, Gunnar Aksel [Show all 7 contributors for this article] (2012). Tuberculosis in goats and sheep in Afar pastoral region of Ethiopia and isolation of Mycobacterium tuberculosis from goat. Veterinary medicine international. ISSN 2090-8113. doi: 10.1155/2012/869146.
  • Dadi, Mengistu Legesse; Ameni, Gobena; Kassa, Gezahegne Mamo; Medhin, Girmay; Bjune, Gunnar Aksel & Abebe, Fekadu (2012). Association of the level of IFN-gamma produced by T cells in response to Mycobacterium tuberculosis-specific antigens with the size of skin test indurations among individuals with latent tuberculosis in a highly tuberculosis-endemic setting. International Immunology. ISSN 0953-8178. 24(2), p. 71–78. doi: 10.1093/intimm/dxr102.
  • Belay, Mulugeta ; Bjune, Gunnar Aksel & Abebe, Fekadu (2011). Serodiagnosis performance of R-ESAT-6-CFP-10 in the diagnosis of pulmonary tuberculosis in Ethiopia. Mycobacterial Diseases. ISSN 2161-1068. 1(2). doi: 10.4172/2161-1068.1000103.
  • Abebe, Dawit Shawel; Bjune, Gunnar Aksel; Ameni, Gobena; Biffa, Demelash & Abebe, Fekadu (2011). Prevalence of pulmonary tuberculosis and associated risk factors in Eastern Ethiopian prisons. The International Journal of Tuberculosis and Lung Disease. ISSN 1027-3719. 15(5), p. 668–673. doi: 10.5588/ijtld.10.0363.
  • Dadi, Mengistu Legesse; Ameni, Gobena; Kassa, Gezahegne Mamo; Medhin, Girmay; Bjune, Gunnar Aksel & Abebe, Fekadu (2011). Community-based cross-sectional survey of latent tuberculosis infection in Afar pastoralists, Ethiopia, using QuantiFERON-TB Gold In-Tube and tuberculin skin test. BMC Infectious Diseases. ISSN 1471-2334. 11. doi: 10.1186/1471-2334-11-89.
  • Dadi, Mengistu Legesse; Ameni, Gobena; Kassa, Gezahegne Mamo; Medhin, Girmay; Bjune, Gunnar Aksel & Abebe, Fekadu (2011). Knowledge of cervical tuberculosis lymphadenitis and its treatment in pastoral communities of the Afar region, Ethiopia. BMC Public Health. ISSN 1471-2458. 11(157). doi: 10.1186/1471-2458-11-157.
  • Kassa, Gezahegne Mamo; Bayleyegn, Gizachew; Tessema, Tesfaye Sisay; Dadi, Mengistu Legesse; Medhin, Girmay & Bjune, Gunnar Aksel [Show all 8 contributors for this article] (2011). Pathology of Camel Tuberculosis and Molecular Characterization of Its Causative Agents in Pastoral Regions of Ethiopia. PLOS ONE. ISSN 1932-6203. 6(1). doi: 10.1371/journal.pone.0015862.
  • Abebe, Dawit Shawel; Biffa, Demelash; Bjune, Gunnar Aksel; Ameni, Gobena & Abebe, Fekadu (2011). Assessment of knowledge and practice about tuberculosis among eastern Ethiopian prisoners. The International Journal of Tuberculosis and Lung Disease. ISSN 1027-3719. 15(2), p. 228–233.
  • Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Abebe, Dawit Shawel & Bjune, Gunnar Aksel [Show all 7 contributors for this article] (2010). Knowledge and perception of pulmonary tuberculosis in pastoral communities in the middle and Lower Awash Valley of Afar region, Ethiopia. BMC Public Health. ISSN 1471-2458. 10(187). doi: 10.1186/1471-2458-10-187.
  • Dadi, Mengistu Legesse; Ameni, Gobena; Kassa, Gezahegne Mamo; Medhin, G; Bjune, Gunnar Aksel & Abebe, Fekadu (2010). Performance of QuantiFERON-TB Gold In-Tube (QFTGIT) for the diagnosis of Mycobacterium tuberculosis (Mtb) infection in Afar Pastoralists, Ethiopia. BMC Infectious Diseases. ISSN 1471-2334. 10. doi: 10.1186/1471-2334-10-354.
  • Biffa, Demelash; Skjerve, Eystein; Oloya, James; Bogale, Asseged; Abebe, Fekadu & Dahle, Ulf R [Show all 8 contributors for this article] (2010). Molecular characterization of Mycobacterium bovis isolates from Ethiopian cattle. BMC Veterinary Research. ISSN 1746-6148. 6. doi: 10.1186/1746-6148-6-28.
  • Gele, Abdikadir Ali; Sagbakken, Mette; Abebe, Fekadu & Bjune, Gunnar Aksel (2010). Barriers to tuberculosis care: a qualitative study among Somali pastoralists in Ethiopia. BMC Research Notes. ISSN 1756-0500. 3(86). Full text in Research Archive
  • Dadi, Mengistu Legesse; Ameni, Gobena; Medhin, G.; Shawel, Dawit; Bjune, Gunnar Aksel & Abebe, Fekadu (2010). Knowledge and perception of pulmonary tuberculosis in pastoral communities in the middle and Lower Awash Valley of Afar region, Ethiopia. BMC Public Health. ISSN 1471-2458. 10. doi: 10.1186/1471-2458-10-187.
  • Abebe, Fekadu & Bjune, Gunnar Aksel (2009). The protective role of antibody responses during Mycobacterium tuberculosis infection. Clinical and Experimental Immunology. ISSN 0009-9104. 157(2), p. 235–243. doi: 10.1111/j.1365-2249.2009.03967.x.
  • Abebe, Fekadu (2009). Novel Anti-schistosomal Drugs from Medicinal Plants. In Watson, Ronald R. & Preedy, Victor R. (Ed.), Botanical Medicine in Clinical Practice. Oxford University Press. ISSN 9781845934132. p. 175–183.
  • Gele, Abdikadir Ali; Bjune, Gunnar Aksel & Abebe, Fekadu (2009). Pastoralism and delay in diagnosis of TB in Ethiopia. BMC Public Health. ISSN 1471-2458. 9. doi: 10.1186/1471-2458-9-5.
  • Abebe, F; Holm-Hansen, Carol; Wiker, HG & Bjune, G (2007). Progress in serodiagnosis of Mycobacterium tuberculosis infection. Scandinavian Journal of Immunology. ISSN 0300-9475. 66(2-3), p. 176–191. doi: 10.1111/j.1365-3083.2007.01978.x.
  • Abebe, Fekadu & Bjune, Gunnar Aksel (2006). The emergence of Beijing family genotypes of Mycobacterium tuberculosis and low-level protection by bacille Calmette-Guerin (BCG) vaccines: is there a link? Clinical and Experimental Immunology. ISSN 0009-9104. 145, p. 389–397.
  • Abebe, Fekadu; Mustafa, T; Nerland, A. & Bjune, Gunnar Aksel (2006). Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease. Clinical and Experimental Immunology. ISSN 0009-9104. 143, p. 180–192.
  • Abebe, Fekadu; Erko, Berhanu; Gemetchu, T & Gundersen, Svein Gunnar (2005). Control of Biomphalaria pfeifferi population and schistosomiasis transmission in Ethiopia using the soap berry endod (Phytolacca dodecandra), with special emphasis on application methods. Transactions of the Royal Society of Tropical Medicine and Hygiene. ISSN 0035-9203. 99(10), p. 787–794.
  • Abebe, Fekadu; Erko, B; Gemetchu, T & Gundersen, SG (2005). Control of Biomphalaria pfeifferi population and schistosomiasis transmission in Ethiopia using the soap berry endod (Phytolacca dodecandra), with special emphasis on application methods. Transactions of the Royal Society of Tropical Medicine and Hygiene. ISSN 0035-9203. 99, p. 787–794.
  • Abebe, Fekadu; Birkeland, Kåre I; Garder, P. I.; Petros, B & Gundersen, Svein Gunnar (2002). The relationships between dehydroepiandrosterone sulphate DHEAS), the intensity of Schistosoma mansoni infection and parasite-specific antibody responses. A cross-sectional study in residents of endemic communities in north-east Ethiopia. APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. ISSN 0903-465X.
  • Erko, Berhanu; Abebe, Fekadu; Berhe, Nega; Medhin, G; Gebre-Michael, T & Gundersen, Svein Gunnar (2002). Control of Schistosoma mansoni by the soapberry Endod (Phytolacca dodecandra) in Wollo, northeastern Ethiopia: post-intervention prevalence. East African Medical Journal. ISSN 0012-835X. 79(4), p. 198–201.
  • Erko, Berhanu; Medhin, G; Abebe, Fekadu; Gebre-Michael, T & Gundersen, Svein Gunnar (2002). Epidemiological studies on intestinal schistosomiasis in Wondo Genet, southern Ethiopia. Ethiopian Medical Journal. ISSN 0014-1755. 40(1), p. 29–39.
  • Abebe, Fekadu; Gaarder, Per Ivar; Petros, B & Gundersen, Svein Gunnar (2002). Differences in prevalence, intensity of infection and parasite-specific antibody levels do not predict different age-infection profiles. ?. 110(07.aug), p. 535–544.

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  • Abebe, Fekadu (2017). utfordringer ved bruk av gammainterferon-frigjøringstester for å diagnostisere tuberkulose. BestPractice Norge.
  • Inotu, Adolphus & Abebe, Fekadu (2014). Assessment of defaulting from directly observed treatment short course (DOTS) and its determinants in Benin city, Nigeria. Journal of Tuberculosis Research. ISSN 2329-8448. 2(1), p. 30–39. doi: 10.4236/jtr.2014.21004.
  • Shero, Kebede Chimdessa; Legesse, Mengistu; Medhin, Girmay; Belay, Mulugeta; Bjune, Gunnar Aksel & Abebe, Fekadu (2014). Re-assessing tuberculin skin test (TST) for the diagnosis of tuberculosis (TB) among African migrants in Western Europe and USA. Journal of Tuberculosis Research. ISSN 2329-8448. 2(1), p. 4–15. doi: 10.4236/jtr.2014.21002.
  • Legesse, Mengistu; Mamo, Gezahegne; Ameni, Gobena; Medhin, Girmay; Bjune, Gunnar Aksel & Abebe, Fekadu (2013). Community-based prevalence of undiagnosed mycobacterial diseases in the Afar Region, north-east Ethiopia. International Journal of mycobacteriology. ISSN 2212-5531. 2(2), p. 94–102. doi: 10.1016/j.imyco.2013.04.001.
  • Mamo, Gezahegne; Abebe, Fekadu; Worku, Yalelet; Hussein, Nesredin; Legesse, Mengistu & Tilahun, Getachew [Show all 9 contributors for this article] (2013). Bovine tuberculosis and its associated risk factors in pastoral and agro-pastoral cattle herds of Afar Region. northeast Ethiopia. Academic journals.

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Published Apr. 13, 2011 2:45 PM - Last modified Feb. 1, 2019 11:29 AM