Nikolaj Kunøe

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Visiting address Forskningsveien 3A Harald Schjelderups hus inng.2 3.etg 0373 Oslo
Postal address Postboks 1089 Blindern 0317 Oslo

Academic interests

Acute and long-term serious mental health challenges and facilitating their recovery, including:

Substance dependence, including opioid- and alcohol dependence, and poly-substance use

Psychotic states and disorders including bipolar disorder and schizophrenia spectrum disorders

Pharmacological and non-pharmacological aids to recovery and harm prevention

Courses taught

  • https://www.uio.no/studier/emner/medisin/helsefag/HELSEF4302/ 

Background

PhD in 2010 and Postdoctoral fellowships at the University of Oslo, Medical Faculty, within investigator-initiated trials of long-acting naltrexone to prevent relapse to heroin addiction & - overdose. Funded by public grants. 

Clinical (licensed) psychologist and specialist psychologist in mental health & addiction

Lecturing assignments at the University of Oslo since 1998.

Awards

  • Acute psychiatry network prize in 2018 (with PhD candidate as lead author)
  • 2022 Henk Nijman award for best abstract in research on coercion reduction (with postdoctoral candidate as lead author)

Appointments

  • 2022: Associate professor at the University of Oslo

 

Publications

  • Rustad Indregard, Anne Marthe; Nussle, Hans Martin; Småstuen, Milada Cvancarova; Vandvik, Per Olav; Tesli, Martin Steen & Gather, Jakov [Show all 7 contributors for this article] (2024). Open-door policy versus treatment-as-usual in urban psychiatric inpatient wards: a pragmatic, randomised controlled, non-inferiority trial in Norway. The Lancet Psychiatry. ISSN 2215-0374. doi: 10.1016/S2215-0366(24)00039-7.
  • Opheim, Arild; Saltyte Benth, Jurate; Solli, Kristin Klemmetsby; Kloster, Pia Synnøve; Fadnes, Lars T. & Kunøe, Nikolaj [Show all 8 contributors for this article] (2023). Risk of relapse to non-opioid addictive substances among opioid dependent patients treated with an opioid receptor antagonist or a partial agonist: A randomized clinical trial. Contemporary Clinical Trials. ISSN 1551-7144. 135. doi: 10.1016/j.cct.2023.107360. Full text in Research Archive
  • Kunøe, Nikolaj; Antonsen, Bjørnar Torske; Ebeling, Benjamin & Bruun, Sissel (2022). Kortvarige brukerstyrte innleggelser som alternativ til tvangsinnleggelse hos pasienter med alvorlig selvskading. Tidsskrift for Norsk Psykologforening. ISSN 0332-6470. 59(6), p. 548–557. doi: 10.52734/6MP76v23.
  • Kunøe, Nikolaj; Nussle, Hans Martin & Rustad Indregard, Anne Marthe (2022). Protocol for the Lovisenberg Open Acute Door Study (LOADS): A pragmatic randomised controlled trial to compare safety and coercion between open-door policy and usual-care services in acute psychiatric inpatients. BMJ Open. ISSN 2044-6055. 12(2). doi: 10.1136/bmjopen-2021-058501.
  • Gaulen, Zhanna; Brenna, Ida Halvorsen; Fadnes, Lars T.; Saltyte Benth, Jurate; Solli, Kristin Klemmetsby & Kunøe, Nikolaj [Show all 8 contributors for this article] (2021). The Predictive Value of Degree of Preference for Extended-Release Naltrexone for Treatment Adherence, Opioid Use, and Relapse. European Addiction Research. ISSN 1022-6877. 28(1). doi: 10.1159/000518436.
  • Opheim, Arild; Gaulen, Zhanna; Solli, Kristin Klemmetsby; Latif, Zill-E-Huma; Fadnes, Lars T. & Saltyte Benth, Jurate [Show all 8 contributors for this article] (2021). Risk of Relapse Among Opioid-Dependent Patients Treated With Extended-Release Naltrexone or Buprenorphine-Naloxone: A Randomized Clinical Trial. American Journal on Addictions. ISSN 1055-0496. 30(5), p. 453–460. doi: 10.1111/ajad.13151. Full text in Research Archive
  • Solli, Kristin Klemmetsby; Opheim, Arild; Latif, Zill-E-Huma; Krajci, Peter; Saltyte Benth, Jurate & Kunøe, Nikolaj [Show all 7 contributors for this article] (2020). Adapting treatment length to opioid-dependent individuals' needs and preferences: A 2-year follow-up to a 1-year study of extended-release naltrexone. Addiction. ISSN 0965-2140. p. 1–10. doi: 10.1111/add.15378. Full text in Research Archive
  • Eikemo, Marie; Lobmaier, Philipp Paul; Pedersen, Mads Lund; Kunøe, Nikolaj; Matziorinis, Anna Maria & Leknes, Siri [Show all 7 contributors for this article] (2019). Intact responses to non-drug rewards in long-term opioid maintenance treatment. Neuropsychopharmacology. ISSN 0893-133X. 44(8), p. 1456–1463. doi: 10.1038/s41386-019-0377-9. Full text in Research Archive
  • Solli, Kristin Klemmetsby; Kunøe, Nikolaj; Latif, Zill-E-Huma; Haase, Kamni Sharma; Opheim, Arild & Krajci, Peter [Show all 9 contributors for this article] (2019). Availability of extended-release naltrexone may increase the number of opioid-dependent individuals in treatment: Extension of a randomized clinical trial. European Addiction Research. ISSN 1022-6877. 25(6), p. 1–7. doi: 10.1159/000501931. Full text in Research Archive
  • Latif, Zill-E-Huma; Solli, Kristin Klemmetsby; Opheim, Arild; Kunøe, Nikolaj; Saltyte Benth, Jurate & Krajci, Peter [Show all 8 contributors for this article] (2019). No increased pain among opioid-dependent individuals treated with extended-release naltrexone or buprenorphine-naloxone: A 3-month randomized study and 9-month open-treatment follow-up study. American Journal on Addictions. ISSN 1055-0496. 38(2), p. 77–85. doi: 10.1111/ajad.12859.
  • Latif, Zill-E-Huma; Saltyte Benth, Jurate; Solli, Kristin Klemmetsby; Opheim, Arild; Kunøe, Nikolaj & Krajci, Peter [Show all 8 contributors for this article] (2018). Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone A Randomized Clinical Trial and Follow-up Study. JAMA psychiatry. ISSN 2168-6238. doi: 10.1001/jamapsychiatry.2018.3537. Full text in Research Archive
  • Solli, Kristin Klemmetsby; Latif, Zill-E-Huma; Opheim, Arild; Krajci, Peter; Haase, Kamni Sharma & Saltyte Benth, Jurate [Show all 8 contributors for this article] (2018). Effectiveness, safety and feasibility of extended-release naltrexone for opioid dependence: a nine-month follow-up to a three-month randomized trial. Addiction. ISSN 0965-2140. 113(10), p. 1840–1849. doi: 10.1111/add.14278.
  • Tanum, Lars; Solli, Kristin Klemmetsby; Latif, Zill-E-Huma; Saltyte Benth, Jurate; Opheim, Arild & Haase, Kamni Sharma [Show all 8 contributors for this article] (2017). Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence. A Randomized Clinical Noninferiority Trial. JAMA psychiatry. ISSN 2168-6238. 74(12), p. 1197–1205. doi: 10.1001/jamapsychiatry.2017.3206.
  • Haase, Kamni Sharma; Kunøe, Nikolaj; Opheim, Arild; Gaulen, Zhanna; Njå, Anne-Lill Mjølhus & Zill E, Huma Latif [Show all 8 contributors for this article] (2016). Interest in extended release naltrexone among opioid users. European Addiction Research. ISSN 1022-6877. 22(6), p. 301–305. doi: 10.1159/000447964.
  • Kunøe, Nikolaj; Opheim, Arild; Solli, Kristin Klemmetsby; Gaulen, Zhanna; Haase, Kamni Sharma & Zill E, Huma Latif [Show all 7 contributors for this article] (2016). Design of a randomized controlled trial of extended-release naltrexone versus daily buprenorphine-naloxone for opioid dependence in Norway (NTX-SBX). BMC Pharmacology & Toxicology. ISSN 2050-6511. 17(1). doi: 10.1186/s40360-016-0061-1.
  • Bukten, Anne; Lund, Ingunn Olea; Rognli, Eline Borger; Riksheim, Marianne; Lobmaier, Philipp Paul & Skurtveit, Svetlana [Show all 8 contributors for this article] (2015). The Norwegian offender mental health and addiction study – Design and implementation of a national survey and prospective cohort study. Substance Abuse: Research and Treatment. ISSN 1178-2218. 9, p. 59–66. doi: 10.4137/SART.S23546. Full text in Research Archive
  • Kunøe, Nikolaj; Lobmaier, Philipp Paul; Hahn, Ngo & Hulse, Gary (2012). Injectable and implantable sustained release naltrexone in the treatment of opioid addiction. British Journal of Clinical Pharmacology. ISSN 0306-5251. doi: 10.1111/bcp.12011.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj; Gossop, Michael & Waal, Helge (2011). Naltrexone Depot Formulations for Opioid and Alcohol Dependence: A Systematic Review. CNS Neuroscience & Therapeutics. ISSN 1755-5930. 17(6), p. 629–636. doi: 10.1111/j.1755-5949.2010.00194.x.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj; Gossop, Michael & Waal, Helge (2010). Naltrexone Depot Formulations for Opioid and Alcohol Dependence: A Systematic Review. CNS Neuroscience & Therapeutics. ISSN 1755-5930. doi: 10.1111/j.1755-5949.2010.00194.x.
  • Kunøe, Nikolaj; Lobmaier, Phillip; Vederhus, John-Kåre; Hjerkinn, Bjørg L; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2010). Retention in naltrexone implant treatment for opioid dependence. Drug and Alcohol Dependence. ISSN 0376-8716. 111(1-2), p. 166–169. doi: 10.1016/j.drugalcdep.2010.03.021.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj; Gossop, Michael; Katevoll, Tormod & Waal, Helge (2010). Naltrexone Implants Compared to Methadone: Outcomes Six Months after Prison Release. European Addiction Research. ISSN 1022-6877. 16(3), p. 139–145. doi: 10.1159/000313336.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Waal, Helge (2010). Treatment research in prison: Problems and solutions in a randomized trial. Addiction Research and Theory. ISSN 1606-6359. 18(1), p. 1–13. doi: 10.3109/16066350802531273.
  • Kunøe, Nikolaj; Lobmaier, Phillip; John-Kåre, Vederhus; Hjerkinn, Bjørg; Gossop, Michael & Hegstad, Solfrid [Show all 8 contributors for this article] (2010). Challenges to antagonist blockade during sustained-release naltrexone treatment. Addiction. ISSN 0965-2140. 105(9), p. 1633–1639. doi: 10.1111/j.1360-0443.2010.03031.x.
  • Waal, Helge; Lobmaier, Philipp Paul; Kunøe, Nikolaj; Kornør, Hege & Krook, Aud L (2009). Fire prosjekter i søkelyset? Hva kan vi lære? In Ruyter, Knut W; Solbakk, Jan Helge & Waal, Helge (Ed.), Rusmiddelbrukeren og forskeren. Etiske prinsipper, erfaringer og ettertanker. Senter for rus- og avhengighetsforskning og Seksjon for medisinsk etikk. ISSN 978-82-303-1257-5. p. 9–28.
  • Kunøe, Nikolaj; Lobmaier, Phillip; Vederhus, John Kåre; Hjerkinn, Bjørg; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2009). Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial. British Journal of Psychiatry. ISSN 0007-1250. 194(6), p. 541–546. doi: 10.1192/bjp.bp.108.055319.
  • Kunøe, Nikolaj; Lobmaier, Philipp Paul; Vederhus, John Kåre; Hjerkinn, Bjørg; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2009). Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial. British Journal of Psychiatry. ISSN 0007-1250. 194, p. 541–546. doi: 10.1192/bjp.bp.108.055319.
  • Lobmaier, Philipp Paul; Kornør, Hege; Kunøe, Nikolaj & Bjørndal, Arild (2008). Sustained-release naltrexone for opioid dependence. Cochrane Database of Systematic Reviews. ISSN 1469-493X. doi: 10.1002/14651858.CD006140.pub2.
  • Hegstad, Solfrid; Khiabani, Hassan Zare; Kristoffersen, Lena; Kunøe, Nikolaj; Lobmaier, Philipp & Christophersen, Asbjørg S. (2008). Drug screening of hair by liquid chromatography-tandem mass spectrometry. Journal of Analytical Toxicology. ISSN 0146-4760. 32(5), p. 364–372.

View all works in Cristin

  • Rustad Indregard, Anne Marthe; Nussle, Hans Martin & Kunøe, Nikolaj (2022). An RCT of a co-created open-door policy versus usual-treatment in acute psychiatric ward care.
  • Rustad Indregard, Anne Marthe; Nussle, Hans Martin & Kunøe, Nikolaj (2022). Using participatory action research to address violence against staff in mental health care.
  • Rustad Indregard, Anne Marthe; Nussle, Hans Martin; Vegerstøl, Kristin; Meisingset, Grete & Kunøe, Nikolaj (2022). Psykisk helsevern: Åpen dør-policy er mer enn en ulåst dør. Sykepleien. ISSN 0802-9768.
  • Nussle, Hans Martin; Kunøe, Nikolaj; Vegerstøl, Kristin & Lund, Grete Meisingset (2022). Psykisk helsevern: Åpen dør-policy er mer enn en ulåst dør. Tidsskriftet sykepleien. ISSN 0806-7511.
  • Jørgenrud, Benedicte Marie; Bogstrand, Stig Tore; Vindenes, Vigdis; Johannessen, Aud; Wüsthoff, Linda Elise & Kunøe, Nikolaj [Show all 9 contributors for this article] (2021). Implementering av intervensjon for skadelig alkohol- og legemiddelbruk blant medisinske pasienter .
  • Kunøe, Nikolaj (2020). Commentary on Nunes et al. (2020): Blocked opioid use in antagonist treatment—time for cognitive and user‐centered perspectives. Addiction. ISSN 0965-2140. 115(2), p. 247–248. doi: 10.1111/add.14847.
  • Kunøe, Nikolaj; Lobmaier, Philipp Paul & Kornør, Hege (2016). Erratum: Removal notice to “Sustained-release naltrexone for opioid dependence: A cochrane review and meta-analysis” (Drug and Alcohol Dependence (2015) 146 (e165–e166)(S037687161401429X)(10.1016/j.drugalcdep.2014.09.367)). Drug and Alcohol Dependence. ISSN 0376-8716. 167, p. 237–237. doi: 10.1016/j.drugalcdep.2016.09.003.
  • SANDERUD, LIVE; Tanum, Lars & Kunøe, Nikolaj (2014). L.S. Stavseth og medarbeidere svarer. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(2), p. 136–137. doi: 10.4045/tidsskr.13.1669.
  • Kunøe, Nikolaj & Lobmaier, Philipp Paul (2011). Twelve-month outcomes of naltrexone implant treatment for opioid dependent outpatients.
  • Kunøe, Nikolaj (2011). Langtidsvirkende naltrekson for opiatavhengighet: en Cochraneanalyse.
  • Kunøe, Nikolaj (2011). A Cochrane review and meta-analysis of sustained release naltrexone for opioid dependence.
  • Kunøe, Nikolaj (2011). Patients receiving opiate substitution have elevated mortality risks at the start and end of treatment. Evidence-Based Mental Health. ISSN 1362-0347. 14(39). doi: 10.1136/ebmh.14.2.39.
  • Kunøe, Nikolaj (2010). Flere veier ut av rusavhengigheten - forskerprofil UiO MedFak. [Internet]. http://www.med.uio.no/forskning/aktuelt/profiler/.
  • Kunøe, Nikolaj & Randsborg, Sissel (2010). Kapsler som opereres inn under huden og blokkerer effekten av heroin kan bli et nytt behandlingstilbud for heroinmisbrukere. [TV]. TV2 Nyheter.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Kornør, Hege (2010). Cochrane review update 2010: Sustained-release naltrexone for opioid dependence.
  • Waal, Helge; Kunøe, Nikolaj; Lobmaier, Philipp Paul & Christophersen, Asbjørg S (2009). Sustained Release Naltrexone, a promising alternative in treatment of opiate addiction.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj; Gossop, Michael & Waal, Helge (2009). A Randomized Controlled Trial on Naltrexone Implants and Methadone Maintenance Among Heroin Dependent Inmates: Results 6 Months After Prison Release.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj; Gossop, Michael & Waal, Helge (2009). A RANDOMIZED CONTROLLED TRIAL ON NALTREXONE IMPLANTS AND METHADONE MAINTENANCE AMONG HEROIN-DEPENDENT INMATES: RESULTS 6 MONTHS AFTER PRISON RELEASE.
  • Willoch, Frode; Lobmaier, Philipp Paul; Kunøe, Nikolaj; Waal, Helge; Andersen, Jannike Mørch & Sundet, Kjetil Søren [Show all 7 contributors for this article] (2008). ”Kognitiv evne og nevrobiologiske prosesser hos heroinavhengige i behandling”.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Waal, Helge (2008). Naltrekson implantat som behandling for heroinavhengighet etter løslatelse fra fengsel - resultater etter 6 måneder.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Waal, Helge (2008). NALTREXONE IMPLANTS FOR OPIOID DEPENDENCE AMONG PRE-RELEASE INMATES.
  • Hegstad, Solfrid; Khiabani, Hassan; Kunøe, Nikolaj; Kristoffersen, Lena & Christophersen, Asbjørg S. (2007). Håranalyser i forbindelse med kontroll av rusmisbrukere under behandling.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Waal, Helge (2006). How to prevent relapse to opioid use after prison release: experiences from an ongoing randomized-controlled trial on naltrexone implants vs. methadone maintenance in custody settings.
  • Lobmaier, Philipp Paul; Kunøe, Nikolaj & Waal, Helge (2006). Naltrexone Implants compared to Methadone Maintenance for relapse prevention after prison release: obstacles in addiction research in custody settings.
  • Kunøe, Nikolaj & Lobmaier, Philipp Paul (2005). Blame the counselling, not the implant. A response to Oliver, Horspool & Keen (2005). Addiction. ISSN 0965-2140. 100(7), p. 1027–8.
  • Bukten, Anne; Stavseth, Marianne Riksheim; Skurtveit, Svetlana; Kunøe, Nikolaj; Lobmaier, Philipp Paul & Lund, Ingunn Olea [Show all 7 contributors for this article] (2016). Rusmiddelbruk og helsesituasjon blant innsatte i norske fengsel. Resultater fra The Norwegian offender mental health and addiction study (NorMA). Universitetet i Oslo. Full text in Research Archive
  • Kunøe, Nikolaj (2010). Sustained release naltrexone for opioid dependence: Effectiveness, safety and clinical feasibility. Unipub forlag. ISSN 978-82-8072-511-0.
  • Kunøe, Nikolaj & Waal, Helge (2010). Sustained release naltrexone for opioid dependence: Effectiveness, safety and clinical feasibility. Unipub forlag. ISSN 978-82-8072-511-0.

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Published June 8, 2022 8:03 AM - Last modified Dec. 16, 2022 10:15 AM