Tricia Lynn Lois Larose

Larose, Tricia L. (2020). 'Tumors in Space: Preparation for Spaceflight', in Pletser, V. (ed). Preparation of Space Experiments. Online: IntechOpen. DOI: 10.5772/intechopen.93465

Larose, Tricia L; Meheus, Filip; Brennan, Paul; Johansson, Mattias; Robbins, Hilary A. (2020). Assessment of Biomarker Testing for Lung Cancer Screening Eligbility. JAMA Network Open. vol. 3 (3). 

Gruber, Sophie; Groemer, Gernot; Paternostro, Simone; Larose, Tricia L. (2020). AMADEE-18 and the Analog Mission Performance Metrics Analysis – a benchmarking tool for mission planning and evaluation. Astrobiology. 

Huang, Joyce Yongxu; Larose, Tricia L; et al. (2019) Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk prediction in the Lung Cancer Cohort Consortium (LC3). International Journal of Cancer. vol. 146 (9). 

Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T. (2019). In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research.vol. 8 (2).

Larose, Tricia L et al. (2018). Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium. International Journal of Epidemiology. vol. 47 (6).

Scélo, Ghislaine; Larose, Tricia L. (2018). Epidemiology and risk factors for kidney cancer. Journal of Clinical Oncology. vol. 36 (36).

Books

Larose, TL. (2020). A Checklist for Dad. International Agency for Research on Cancer: Lyon, France.

Other

Larose, Tricia L. (2019) Female Scientist To Lead Advanced Cancer Research Project In Space. She The People [Internett]. 2019-10-05.

Larose, Tricia L. (2019) Stor strålingsfare i rommet. Hvordan kan romfarere beskyttes mot de høye strålingsdosene de får i rommet?. https://www.romsenter.no/ [Internett]. 2019-06-06.

Larose, Tricia L. (2019) UNOOSA-CMSA Select 6 Experiments For China Space Station. Market News Updates [Internett]. 2019-06-19.

Larose, Tricia L. (2019) United Nations/China Cooperation on the Utilization of the China Space Station (CSS: Selected Experiment Projects to be executed on board the CSS for the 1st Cycle. Announced on the occasion of the 62nd Session of the Committee on the Peaceful Uses of Outer Space, Vienna. United Nations Office for Outer Space Affairs [Internett]. 2019-06-12.

• Guida, Florence; Tan, VY; Corbin, Laura J; Smith-Byrne, K; Alcala, Karine & Langenberg, C [Show all 40 contributors for this article] (2021). The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium. PLoS Medicine. ISSN 1549-1277. 18(9). doi: 10.1371/journal.pmed.1003786. Full text in Research Archive
• Guida, Florence; Tan, VY; Corbin, Laura J; Byrne, Karl Smith; Bull, C & Vincent, E [Show all 11 contributors for this article] (2021). The blood metabolome of incident kidney cancer - Prospective analysis of circulating metabolites and renal cell carcinoma. Submitted and Under Review.
• Akter, Rokshana; Larose, Tricia L; Sandvik, Jannicke; Meland, Anders & Wagstaff, Anthony (2021). Socio-demographic and lifestyle factors associated with abnormal excessive daytime sleepiness in Norwegian military SAR helicopter personnel. Submitted and Under Review.
• Gruber, Sophie; Groemer, Gernot; Paternostro, Simone & Larose, Tricia L (2020). AMADEE-18 and the Analog Mission Performance Metrics Analysis – a benchmarking tool for mission planning and evaluation. Astrobiology. ISSN 1531-1074. 20(11), p. 1295–1302. doi: 10.1089/ast.2019.2034.
• Larose, Tricia L; Meheus, Filip; Brennan, Paul; Johansson, Mattias & Robbins, Hilary A. (2020). Assessment of Biomarker Testing for Lung Cancer Screening Eligibility. JAMA Network Open. ISSN 2574-3805. 3(3), p. 1–3. doi: 10.1001/jamanetworkopen.2020.0409.
• Balasuriya, Chandima Nirupa Dilruks; Larose, Tricia L; Mosti, Mats Peder; Evensen, Kari Anne Indredavik; Jacobsen, Geir Wenberg & Thorsby, Per Medbøe [Show all 8 contributors for this article] (2019). Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up. PLOS ONE. ISSN 1932-6203. 14:e0222712(9), p. 1–15. doi: 10.1371/journal.pone.0222712. Full text in Research Archive
• Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N.; Wang, Renwei; Fanidi, Anouar & Alcala, Karine [Show all 54 contributors for this article] (2019). Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). International Journal of Cancer. ISSN 0020-7136. 146(9), p. 2394–2405. doi: 10.1002/ijc.32555. Full text in Research Archive
• Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M & Scélo, Ghislaine [Show all 9 contributors for this article] (2019). In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research. ISSN 2279-9028. 8(2), p. 62–66. doi: 10.4081/jphr.2019.1550. Full text in Research Archive
• Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf & Grankvist, Kjell [Show all 45 contributors for this article] (2019). Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: Nested case-control study within Lung Cancer Cohort Consortium. The BMJ. ISSN 1756-1833. 364:k4981, p. 1–9. doi: 10.1136/bmj.k4981. Full text in Research Archive Show summary

  Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but have lacked power to comprehensively investigate associations by smoking status and histological subtype. Our objective was to conduct a comprehensive analysis of prospectively measured circulating high-sensitivity CRP (hs-CRP) concentration and risk of lung cancer overall, by smoking status (current, former and never smokers), and histological sub-type. Design: Pooled analysis of prospective case-control studies nested within 20 population cohort studies. Setting: Population-based cohort studies in the Asia, Europe, Australia, and the United States. Participants: 5299 incident lung cancer cases, with individually incidence-density matched controls. Exposure: Circulating hs-CRP concentrations in pre-diagnostic serum/plasma samples. Main Outcome Measure: Incident lung cancer diagnosis. Results: We observed a positive association between circulating hs-CRP concentration and risk of lung cancer for current (OR per doubling in hs-CRP [ORlog2CRP]: 1.09, 95% CI: 1.05 to 1.13) and former smokers (ORlog2CRP 1.09, 95% CI: 1.04 to 1.14), but not never smokers (p-interaction <0.01). This association was strong and consistent across all histological subtypes, with the exception of adenocarcinoma, which was not strongly associated with risk regardless of smoking status (ORlog2CRP adenocarcinoma overall: 0.97, 95%CI: 0.94 to 1.01). Among current and former smokers, the associations were strongest within the first two years of follow-up. Including hs-CRP in a risk model in addition to smoking-based variables did not improve risk discrimination overall, but slightly improved discrimination for cancers diagnosed in the first two years of follow-up. Conclusions: Ever smokers with higher circulating hs-CRP concentrations had higher risk of lung cancer overall. hs-CRP was not associated with risk of lung adenocarcinoma. Circulating hs-CRP concentration may be a pre-diagnostic marker of lung cancer rather than a causal risk factor.

• Liauw, Jessica; Jacobsen, Geir Wenberg; Larose, Tricia L & Hutcheon, Jennifer A (2018). Short interpregnancy interval and poor fetal growth: evaluating the role of pregnancy intention. Paediatric and Perinatal Epidemiology. ISSN 0269-5022. 33(1), p. O73–O85. doi: 10.1111/ppe.12506. Full text in Research Archive
• Scélo, Ghislaine & Larose, Tricia L (2018). Epidemiology and risk factors for kidney cancer. Journal of Clinical Oncology. ISSN 0732-183X. 36(36), p. 3574–3581. doi: 10.1200/JCO.2018.79.1905. Show summary

  The purpose of this narrative review is to summarize evidence of the epidemiology of and risk factors for kidney cancer with a focus on renal cell carcinoma in adults. The etiology of kidney cancer is largely unknown and the main epidemiologic determinants are large geographic and temporal variations in incidence rates. Established risk factors include tobacco smoking, body size, and history of hypertension and chronic kidney disease. Other suspected risk factors require additional investigation, as do the underlying biologic mechanisms that are responsible for disease occurrence. Opportunities to prevent kidney cancer include targeting modifiable risk factors—for example, smoking abstinence/cessation and body weight control—as well as interventions along the diagnostic pathway to improve early diagnosis. Molecular epidemiology, including, but not limited to, metabolomics and tumor genomics, are new areas of research that promise to play important roles in identifying some of the underlying causes of kidney cancer.

• Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian & Stevens, Victoria L. [Show all 53 contributors for this article] (2018). Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). International Journal of Epidemiology. ISSN 0300-5771. 47(6), p. 1760–1771. doi: 10.1093/ije/dyy100. Full text in Research Archive Show summary

• Muller, David C.; Hodge, Allison M.; Fanidi, Anouar; Albanes, Demetrius; Mai, Xiao-Mei & Shu, Xiao Ou [Show all 45 contributors for this article] (2018). No association between circulating concentrations of vitamin D and risk of lung cancer: An analysis in 20 prospective studies in the Lung Cancer Cohort Consortium (LC3). Annals of Oncology. ISSN 0923-7534. 29(6), p. 1468–1475. doi: 10.1093/annonc/mdy104. Full text in Research Archive
• Ranøyen, Ingunn; Lydersen, Stian; Larose, Tricia L; Weidle, Bernhard; Skokauskas, Norbert & Thomsen, Per Hove [Show all 8 contributors for this article] (2018). Developmental course of anxiety and depressive disorders from adolescence to young adulthood in a prospective Norwegian clinical cohort. European Child and Adolescent Psychiatry. ISSN 1018-8827. p. 1–11. doi: 10.1007/s00787-018-1139-7. Full text in Research Archive
• Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Sandanger, Torkjel M; Odland, Jon Øyvind & van de Bor, Margot [Show all 7 contributors for this article] (2018). Prenatal exposure to persistent organic pollutants and child overweight/obesity at 5-year follow-up: A prospective cohort study. Environmental health. ISSN 1476-069X. 17(9). doi: 10.1186/s12940-017-0338-x. Full text in Research Archive
• Larose, Tricia L; Turner, Steve W; Hutcheon, Jennifer A; Rogne, Tormod; Riphagen, Ingrid Ingeborg & Martinussen, Marit [Show all 7 contributors for this article] (2017). Longitudinal ultrasound measures of fetal growth and offspring outcomes. Current Epidemiology Reports. ISSN 2196-2995. 4(2), p. 98–105. doi: 10.1007/s40471-017-0103-2. Full text in Research Archive
• Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Sandanger, Torkjel M; Odland, Jon Øyvind & van de Bor, Margot [Show all 7 contributors for this article] (2017). Maternal serum levels of perfluoroalkyl substances and organochlorines and indices of fetal growth: a Scandinavian case-cohort study. Pediatric Research. ISSN 0031-3998. 81(1), p. 33–42. doi: 10.1038/pr.2016.187. Full text in Research Archive
• O'Brien, Sarah J; Larose, Tricia L; Adak, Goutam K; Evans, Meirion R & Tam, Clarence C (2016). Modelling study to estimate the health burden of foodborne diseases: Cases, general practice consultations and hospitalisations in the UK, 2009. BMJ Open. ISSN 2044-6055. 6(9). doi: 10.1136/bmjopen-2016-011119. Full text in Research Archive
• Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Odland, Jon Øyvind; van de Bor, Margot & Jacobsen, Geir Wenberg [Show all 7 contributors for this article] (2016). Factors associated with maternal serum levels of perfluoroalkyl substances and organochlorines: A descriptive study of parous women in Norway and Sweden. PLOS ONE. ISSN 1932-6203. 11(11). doi: 10.1371/journal.pone.0166127. Full text in Research Archive
• O'Brien, Sarah J; Larose, Tricia L; Adak, Goutam K; Evans, Meirion R & Tam, Clarence C (2016). A modelling study to estimate the health burden of foodborne disease: cases, general practice consultations and hospitalisations in the UK, 2009. BMJ Open. ISSN 2044-6055. 6. doi: 10.1136/bmjopen-2016-011119.
• Larose, Tricia L; Brumpton, Ben Michael; Langhammer, Arnulf; Camargo, Carlos A; Chen, Yue & Romundstad, Pål Richard [Show all 7 contributors for this article] (2015). Serum 25-hydroxyvitamin D level, smoking and lung function in adults: the HUNT Study. European Respiratory Journal. ISSN 0903-1936. 46(2), p. 355–363. doi: 10.1183/09031936.00226614. Full text in Research Archive
• Larose, Tricia L; Langhammer, Arnulf; Chen, Yue; Camargo, Carlos A; Romundstad, Pål Richard & Mai, Xiao-Mei (2015). Serum 25-hydroxyvitamin D levels and lung function in adults with asthma: the HUNT Study. European Respiratory Journal. ISSN 0903-1936. 45(4), p. 1019–1026. doi: 10.1183/09031936.00069714. Full text in Research Archive
• Parkinson, Alan J; Evengard, B; Semenza, Jan C; Ogden, Nicholas; Børresen, Malene L & Berner, J [Show all 17 contributors for this article] (2014). Climate change and infectious diseases in the Arctic: Establishment of a circumpolar working group. International Journal of Circumpolar Health. ISSN 1239-9736. 73, p. 1–7. doi: 10.3402/ijch.v73.25163. Full text in Research Archive
• Larose, Tricia L; Chen, Yue; Camargo, Carlos Arthuro; Langhammer, Arnulf; Romundstad, Pål Richard & Mai, Xiao-Mei (2014). Factors associated with vitamin D deficiency in a Norwegian population: the HUNT Study. Journal of Epidemiology and Community Health. ISSN 0143-005X. 68(2), p. 165–170. doi: 10.1136/jech-2013-202587. Full text in Research Archive
• Lefebvre, Stephanie; Montgomery, Phyllis; Michel, Isabelle; Warren, Claire; Larose, Tricia L & Kauppi, Carol (2012). The Role of Public Health Inspectors in Maintaining Housing in Northern and Rural Communities: Recommendations to Support Public Health Practice. Canadian journal of public health. ISSN 0008-4263. 103(2), p. 84–89. doi: 10.1007/bf03404208. Full text in Research Archive
• Maar, Marion; Gzik, Danusia & Larose, Tricia L (2010). Beyond Expectations: Why Do Aboriginal and Euro-Canadian Patients with Type 2 Diabetes on a Northern, Rural Island Demonstrate Better Outcomes for Glycemic, Blood Pressure and Lipid Management than Comparison Populations? Canadian Journal of Diabetes. ISSN 1499-2671. 34(2), p. 127–135. Full text in Research Archive
• Maar, Marion A; Erskine, Barbara; McGregor, Lorrilee; Larose, Tricia L; Sutherland, Mariette E & Graham, Douglas [Show all 8 contributors for this article] (2009). Innovations on a shoestring: a study of a collaborative community-based Aboriginal mental health service model in rural Canada. International Journal of Mental Health Systems. ISSN 1752-4458. 3(27). doi: 10.1186/1752-4458-3-27. Full text in Research Archive

View all works in Cristin

• Larose, Tricia L (2020). Tumors in Space: Preparation for Spaceflight. IntechOpen. ISBN 978-1-78985-138-0. 17 p.
• Larose, Tricia L (2020). A Checklist for Dad. WHO press. ISBN 978-92-832-0449-7. 64 p.

View all works in Cristin

• Akter, Rokshana; Larose, Tricia L; Sandvik, Jannicke; Fonne, Vivianne; Meland, Anders & Wagstaff, Anthony Sverre (2021). Excessive Daytime Sleepiness and Associated Factors in Military Search and Rescue Personnel. Aerospace Medicine and Human Performance. ISSN 2375-6314. 92(12), p. 975–979. doi: 10.3357/AMHP.5946.2021.
• Larose, Tricia L (2021). Launch of Tianhe space station core module into orbit. Tumors in Space. . [TV]. CGTN Beijing.
• Larose, Tricia L (2021). China's Tianhe launch brings hope to space experiments and cancer research .
• Larose, Tricia L (2021). Launch of China Space Station Core Module. Tumors in Space. . [TV]. Dialogue live in London studio. .
• Larose, Tricia L (2021). Shenzhou-12 crewed mission to CSS. Tumors in Space Experiment. C. [TV]. GTN live studio programming in Beijing. .
• Larose, Tricia L (2021). Fighting Cancer in Space. Tech it Out with Yang Zhao.
• Larose, Tricia Lynn Lois (2021). How to be a free electron .
• Larose, Tricia Lynn Lois (2021). Tumors in Space.
• Larose, Tricia Lynn Lois (2021). Environmental Control and Life Support System.
• Larose, Tricia Lynn Lois (2021). Tumors in Space .
• Larose, Tricia Lynn Lois (2021). Spaceflight Hardware II.
• Larose, Tricia Lynn Lois (2021). Spaceflight Hardware I.
• Larose, Tricia Lynn Lois (2021). Tumors in Space: Preparation for Spaceflight.
• Larose, Tricia Lynn Lois (2021). The History of Cancer.
• Larose, Tricia Lynn Lois (2021). Learning from past researchers.
• Larose, Tricia Lynn Lois (2021). Introduction to Molecular Biology.
• Lehnhardt, Kris; Diaz Artiles, Ana & Larose, Tricia Lynn Lois (2021). In situ resource training .
• de la Torre, Gabriel; Diaz Artiles, Ana; Wotring, Virginia & Larose, Tricia Lynn Lois (2021). Astro Training IV: Human Performance in Analog Environments.
• Drego, Adelia; Nählinder, Steffan & Larose, Tricia Lynn Lois (2021). Astro Training II: Aerospace Human Factors .
• da Silveira, Willian; Wotring, Virginia & Larose, Tricia Lynn Lois (2021). SpaceOMICS.
• de la Torre, Gabriel; Diaz Artiles, Ana; Wotring, Virginia & Larose, Tricia Lynn Lois (2021). Cognitive Neuroscience and Brain-Tech Interface.
• Chattopadhyay, Bodhisattva; Thorsson, Bergsveinn; Kanyu Wang, Regina & Larose, Tricia Lynn Lois (2021). Speculative Space Futures .
• Larose, Tricia Lynn Lois (2021). Astro Training I: Resilience.
• Larose, Tricia L; da Silveira, Willian; Riester, Muriel; Welch, Chris & Wotring, Virginia (2021). A digital approach to Space-OMICS teaching at the International Space University. Submitted and Under Review.
• Larose, Tricia L (2020). Casual Space Podcast with Beth Mund. Episode 97. Tumors in Space with Dr. Tricia Larose. Show summary

  Casual Space Podcast with Beth Mund. Episode 97

• Larose, Tricia L (2020). How to talk to children about cancer.
• Larose, Tricia L (2020). When research includes writing children´s books.
• Larose, Tricia Lynn Lois (2020). Tumors in Space.
• Larose, Tricia Lynn Lois (2020). Tumors in Space.
• Larose, Tricia L (2019). Scientists Race To Use Zero Gravity To Kill The Worst Cancers.
• Larose, Tricia L (2019). Cancer research on Chinese space station could lead to new therapies to fight disease, by studying effects of gravity on tumours. [Internet]. South China Morning Post.
• Larose, Tricia L (2019). Female Scientist To Lead Advanced Cancer Research Project In Space. [Internet]. She The People.
• Larose, Tricia L (2019). Cancer cells to be tested in zero gravity on Chinese Space Station. [Internet]. E&T Engineering and Technology.
• Larose, Tricia L (2019). New project to examine roles of microgravity and cosmic radiation in tumor growth, development. [Internet]. News Medical Life Sciences.
• Larose, Tricia L (2019). 'Tumors in Space' project studies cancer risk of cosmic radiation. [Internet]. Psyc.Org News.
• Larose, Tricia L (2019). Tumours in Space studies tumours, cancer risk of radiation. [Internet]. Norwegian SciTech News.
• Larose, Tricia L (2019). Here’s What China Will Be Doing With Its New Space Station. [Internet]. RADII.
• Larose, Tricia L (2019). China Discloses their Scientific Experiments for another space station. [Internet]. Industry Global News24.
• Larose, Tricia L (2019). Vaccine opinions, space-station science and Hong Kong protests. The week in science: 14–20 June 2019. [Internet]. Nature - International Journal of Science.
• Larose, Tricia L (2019). UNOOSA-CMSA Select 6 Experiments For China Space Station. [Internet]. Market News Updates.
• Larose, Tricia L (2019). China reveals scientific experiments for its next space station. Projects will probe topics including DNA mutation, fire behaviour and the birth of stars. [Internet]. Nature - International Journal of Science. Show summary

  China has selected nine scientific experiments — including a project that will probe how DNA mutates in space — to fly on its first major space station, scheduled to be completed in 2022. The China Manned Space Agency selected the projects, which involve scientists from 17 nations, from 42 hopefuls, in a process organized with the United Nations Office for Outer Space Affairs (UNOOSA). China’s existing space laboratory, Tiangong-2, which launched in 2016, also hosts experiments, but the new space station will be bigger and is intended to last longer. Known as the China Space Station, the outpost will be less than one-quarter of the mass of the International Space Station (ISS). The science projects cover similar topics to experiments that have flown on the ISS since its launch in 1998, including fluid and fire behaviour, biology and astronomy. Scientists working on the projects hail from spacefaring nations such as Russia, Japan and India, as well as low- and middle-income countries including Kenya, Mexico and Peru — the result of a special effort to encourage participation from such nations. “The cooperation takes into account the special needs of developing countries, which were encouraged to submit joint project applications with developed countries,” said Wang Qun, China’s ambassador to the United Nations in Vienna, in a statement. The experiments include an Indian–Russian observatory called Spectroscopic Investigations of Nebular Gas, which will map dust clouds and star-forming regions of space using ultraviolet light. A group of European institutions, meanwhile, will study how microgravity and radiation in space affect the mutation of DNA in human ‘organoids’ — 3D biological structures that mimic organs. And a Saudi Arabian team will test how solar cells perform on the outside of the space station. Other winners include a detector called POLAR-2, a more powerful follow-up to a sensor launched on Tiangong-2 to study the polarization of energetic γ-ray bursts from distant cosmic phenomena. POLAR-2, which will be built by an international collaboration, could even allow astronomers to observe the weak radiation associated with sources of gravitational waves. But none of the experiments come from the United States, which since 2011 has forbidden NASA researchers from collaborating with China without congressional approval. A spokesperson for UNOOSA told Nature that US scientists were eligible to take part and were involved in several applications, but those projects weren’t ultimately selected. The United States is planning to cut its funding for the ISS from 2024, as it concentrates its space efforts on building an outpost in the Moon’s orbit from 2022. This could mean that the Chinese space station becomes scientists’ only laboratory in low Earth orbit from 2024.

• Larose, Tricia L (2019). United Nations/China Cooperation on the Utilization of the China Space Station (CSS: Selected Experiment Projects to be executed on board the CSS for the 1st Cycle. Announced on the occasion of the 62nd Session of the Committee on the Peaceful Uses of Outer Space, Vienna. [Internet]. United Nations Office for Outer Space Affairs. Show summary

  The United Nations Office for Outer Space Affairs (UNOOSA), in cooperation with the China Manned Space Agency (CMSA) and with the support of the Government of China, published on 28 May 2018 the 1st "Announcement of Opportunity (AO)" under the United Nations/China Cooperation on the Utilization of the China Space Station (CSS) initiative, inviting all Member States of United Nations to submit applications for conducting their scientific experiments on board the CSS. As of 30 September 2018, which was the application deadline, a total of 42 applications from institutions in 27 countries were received, and then carefully evaluated by around 60 experts from UNOOSA, CMSA and international space community, in line with the eligibility and selection criteria outlined in the first AO. Eighteen (18) projects out of the 42 received were shortlisted, and their Principal Investigators were invited to prepare their Implementation Scheme Proposals (ISPs) for further review towards a final selection. By the submission deadline of 20 April 2019, 15 ISPs from the 18 shortlisted were received and an in-depth review in terms of technical scheme, implementation feasibility, onboard resource requirements, safety analysis, risk analysis, and financial support for their own development was executed. As a final outcome from the application and selection process, nine experiments were selected for entering preparation and implementation process, among which six were fully accepted, and three were conditionally selected. These 9 projects involve 23 institutions from 17 Member States of the United Nations in Asian-pacific, European, African, North American and South American regions, including governmental organizations, private sectors, and international associations. It is, indeed, great to see that most of the projects are collaborative international efforts reflecting the creativity and commitment of the involved scientists from public and private entities in both developing and developed countries. The research areas involve space life science, biotechnology, microgravity fluid physics, microgravity combustion, astronomy, and space technologies. Details about the selected experiment projects are as follows.

• Larose, Tricia L (2019). International experiments selected to fly on Chinese Space Station. [Internet]. https://spacenews.com/.
• Larose, Tricia L (2019). Stor strålingsfare i rommet. Hvordan kan romfarere beskyttes mot de høye strålingsdosene de får i rommet? [Internet]. https://www.romsenter.no/.
• Larose, Tricia L; Robbins, Hilary A; Brennan, Paul; Meheus, Filip & Johannson, Mattias (2019). Could biomarker-based eligibility for lung cancer screening be cost-effective?
• Larose, Tricia L (2018). Circulating cotinine concentrations and lung cancer risk evaluated in 20 international cohorts.
• Johannson, Mattias; Brennan, Paul; Robbins, Hilary & Larose, Tricia L (2018). The Lung Cancer Cohort Consortium (LC3).
• Fanidi, Anouar; Carreras-Torres, Robert; Larose, Tricia L; Yuan, Jian-Min; Stevens, Victoria L & Weinstein, Stephanie J [Show all 56 contributors for this article] (2018). Is high vitamin B12 status a cause of lung cancer? International Journal of Cancer. ISSN 0020-7136. p. 1–6. doi: 10.1002/ijc.32033. Show summary

  Vitamin B supplementation can have side effects for human health, including cancer risk. We aimed to elucidate the role of vitamin B12 in lung cancer aetiology via direct measurements of pre-diagnostic circulating vitamin B12 concentrations in a nested case-control study, complemented with a Mendelian randomization (MR) approach in an independent case-control sample. We used pre-diagnostic biomarker data from 5,183 case-control pairs nested within 20 prospective cohorts, and genetic data from 29,266 cases and 56,450 controls. Exposures included directly measured circulating vitamin B12 in pre-diagnostic blood samples from the nested case-control study, and 8 single nucleotide polymorphisms associated with vitamin B12 concentrations in the MR study. Our main outcome of interest was increased risk for lung cancer, overall and by histological subtype, per increase in circulating vitamin B12 concentrations. We found circulating vitamin B12 to be positively associated with overall lung cancer risk in a dose response fashion (odds ratio for a doubling in B12 [ORlog2B12 ] = 1.15, 95% confidence interval (95%CI) = 1.06-1.25). The MR analysis based on 8 genetic variants also indicated that genetically determined higher vitamin B12 concentrations were positively associated with overall lung cancer risk (OR per 150 pmol/L standard deviation increase in B12 [ORSD ]= 1.08, 95%CI= 1.00-1.16). Considering the consistency of these two independent and complementary analyses, these findings support the hypothesis that high vitamin B12 status increases the risk of lung cancer.

• Larose, Tricia L; Guida, Florence; Brennan, Paul & Johansson, Mattias (2017). Circulating cotinine concentrations, self-reported smoking, and lung cancer risk in the Lung Cancer Cohort Consortium (LC3).
• Larose, Tricia L; Van Baalan, Mary; McAvinia, Ruth; Skanke, Petter Evju; Wilder, Anderson & Diaz Artiles, Ana (2017). Melanoma or Mars? Follow Your Moral Compass.
• Larose, Tricia L (2017). Local Inspiration Leads To Global Aspirations. [Internet]. nosm.ca Northern Passages Newsletter Vol.17(1).
• Larose, Tricia L (2017). I mars kan du glede deg hver eneste dag Lei mørketiden? Da er mars din måned, for det er nemlig den måneden i året hvor lengden på dagene øker raskest. [Internet]. NRK.no livsstil.
• Lauritzen, Hilde Brun; Larose, Tricia L; Sandanger, Torkjel M; Odland, Jon Øyvind; Van De Bor, Margot & Jacobsen, Geir Wenberg (2016). Maternal levels of perfluoroalkyl substances in relation to fetal growth.
• Larose, Tricia L (2015). Lite sol og lite fisk? Slik får du nok D-vitamin Om vinterhalvåret risikerer vi å få for lite av det mye omtalte vitaminet. [Internet]. NRK.no livsstil.
• Larose, Tricia L; Brumpton, Ben Michael; Langhammer, Arnulf; Camargo, Carlos A; Chen, Yue & Romundstad, Pål Richard [Show all 7 contributors for this article] (2014). Cross-Sectional and Prospective Cohort Study of Serum 25-Hydroxyvitamin D Level, Smoking and Lung Function in a General Population of Adults: The HUNT Study.
• Larose, Tricia L; Langhammer, Arnulf; Chen, Yue; Camargo Jr., Carlos A; Romundstad, Pål Richard & Mai, Xiao-Mei (2013). Vitamin D deficiency and lung function in adults with asthma: the HUNT Study.
• Larose, Tricia L; Chen, Yue; Romundstad, Pål Richard; Langhammer, Arnulf; Camargo Jr., Carlos A & Mai, Xiao-Mei (2012). Prevalence of vitamin D deficiency and associated factors in a Norwegian population: the HUNT Study.
• Larose, Tricia L (2012). Vitamin D status in Norway - an epidemiological overview.
• Maar, Marion A; Gzik, Danusia & Larose, Tricia L (2010). Beyond expectations: Why do Aboriginal and Euro-Canadian patients with type 2 diabetes on a rural island in Northern Ontario demonstrate better outcomes for glycemic, blood pressure and lipid management than comparison populations.
• Larose, Tricia L; Montgomery, Phyllis; Michel, Isabelle; Lefebvre, Stephanie; Warren, Claire & Kauppi, Carol [Show all 7 contributors for this article] (2010). Maintaining housing in North Eastern communities: the potential role of public health inspectors.
• Lefebvre, Stephanie; Montgomery, Phyllis; Michel, Isabelle; Warren, Claire; Larose, Tricia L & Kauppi, Carol (2010). A man's home is his castle. The role of public health inspectors in maintaining housing in northern and rural communities.
• Maar, Marion A; Gzik, Danusia & Larose, Tricia L (2009). Are electronic medical records an effective way to monitor the quality of diabetes care in practice-based research?
• Ahmed, K; Maar, Marion A; Gzik, Danusia & Larose, Tricia L (2009). Quality of diabetes care among Aboriginal and non-Aboriginal patients with type II diabetes on Manitoulin Island and the Canadian population: a comparative analysis on compliance with the CDA clinical practice guidelines.
• Zmijowskyj, Tim; Strasser, R; Ross, G; Scott, M; Jacklin, Kristen & Maar, Marion A [Show all 12 contributors for this article] (2008). ICEPHC: Initiative for Clinical Evaluations in Primary Health Care - unlocking the potential for collaborative research in Northern Ontario.
• Maar, Marion A; Zmijowskyj, Tim; Larose, Tricia L; Graham, Douglas; Williamson, P & Beaudin, R (2008). The Manitoulin Regional Aboriginal Diabetes Care and Management Research Project.

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