Methodology and Epidemiology
Location: Rotterdam (Netherlands)
This course will provide an introduction to the cohort and other longitudinal designs for students with an intermediate level background in epidemiology. It will focus on design and interpretation, emphasizing the principles and complexities of data collection over time and potential biases that may affect cohort data. Topics to be covered include cohort definition, follow-up and definition of outcomes, fixed and time-dependent exposures, quality control, mixed study designs (nested case-control and other studies), and quality assurance and control. The course will also cover the use of the cohort design in clinical/translational research.
Advanced Clinical Trials
The Randomized Controlled Clinical Trial (RCT) is the most reliable method of assessing the efficacy and effectiveness of interventions. In order to provide the best possible evidence-based health care, health professionals must be able to judge the scientific merits and clinical relevance of published RCTs. In addition, they may be involved in designing and performing a RCT and are frequently asked to recruit patients for RCTs.
Advanced Decision Modeling
This weeklong, project-based course aims to provide students with an understanding of advanced methods used in decision-analytic modeling and cost-effectiveness analyses. These include topics like the latest methods for calibration and validation, quantifying uncertainty, and consideration of heterogeneity of patient benefits and equity issues. The course combines lectures and readings to give theoretical foundation and perspectives with in depth project work and presentations to give practical concrete understanding in a way that furthers students’ specific research goals.
Location: Amsterdam (Netherlands)
Clinical Prediction Models
The aim of the course is to provide better knowledge and understanding of the development of prediction models that are relevant to real-life practice. We will focus on the various methods for selecting variables, and the pros and cons of these different methods. Once the prediction model has been developed, it is important to assess the quality of the prediction model. For example, we will look at whether the predictions of the model are accurate and during the course, we will also consider the various ways of measuring accuracy. The question of applying the model to new (future) patients will also be addressed.