Ana Sofia Da Silva Lapao
Academic interests
Understand the molecular mechanisms of selective autophagy of protein aggregates and mitochondria. Identification of new therapeutic targets for selective autophagy related disorders.
Background
2018 - Present: Ph.D. Candidate/ Early Stage Researcher MSCA ITN DRIVE Autophagy, UiO
2015-2017: M.Sc. in Tissue Engineering and Regenerative Medicine, UAS Technikum Wien, Austria
2007-2010: B.Sc. in Biochemistry, University of Minho, Portugal
Publications
S. Lekomtsev, S. Aligianni, A. Lapao, and T. Bürckstümmer, “Efficient generation and reversion of chromosomal translocations using CRISPR/Cas technology,” BMC Genomics, vol. 17, no. 1, p. 739, Dec. 2016.
T. Bürckstümmer, C. Banning, P. Hainzl, R. Schobesberger, C. Kerzendorfer, F. M. Pauler, D. Chen, N. Them, F. Schischlik, M. Rebsamen, M. Smida, F. F. de la Cruz, A. Lapao, M. Liszt, et al., “A reversible gene trap collection empowers haploid genetics in human cells,” Nature Methods, vol. 10, no. 10, pp. 965–971, Aug. 2013.
Publications
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Terešak, Petra; Da Silva Lapao, Ana Sofia; Subic, Nemanja; Boya, Patricia; Elazar, Zvulun & Simonsen, Anne Gjøen (2021). Regulation of PRKN-independent mitophagy. Autophagy. ISSN 1554-8627. 18(1), p. 24–39. doi: 10.1080/15548627.2021.1888244.