Anne Spurkland

Professor - Molecular Immunology
Image of Anne Spurkland
Norwegian version of this page
Phone +47-22851125
Mobile phone +47-41574078
Room 2501
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1105 Blindern 0317 OSLO

Academic interests

  • Autoimmune disease
  • T cell activation
  • Molecular immunology
  • Genetics
  • Neuroinflammation

Courses taught

  • Anatomy
  • Immunity. Evolutionary and patient oriented perspectives.

Background

Education

  • MD. University of Oslo, 1986
  • PhD Universvity of Oslo, 1993
  • Specialised in Immunology and Transfusion Medicine, 2000

Positions held

  • 1988-1992: Research fellow, Norwegian Research Council
  • 1993-1994: Resident physician, Red Cross Blood bank, Oslo
  • 1995: Resident physician, Department of immunology and blood transfusion, Ullevål Hospital, Oslo
  • 1995-1999: Researcher, Institute of transplantation Immunology, Rikshospitalet
  • 2000-2001: Resident physician, Institute of Immunology, Rikshospitalet
  • 2001: Assistant professor, UiO
  • 2001-to present: Professor, UiO

Memberships

  • Member of the Norwegian Academy of Science and Letters
  • Member of the Norwegian Society for Immunology

Collaboration

  • Partner in Genetic Analysis of Multiple Sclerosis in Europeans (GAMES) 2000-dd
  • Partner in International Multiple Sclerosis Consortium (IMSGC) 2008-dd
  • Member of Management Committee COST Neurinfnet 2009-2011
Tags: Blood and immunology, Genetic and epidemiology, Brain and nervous system, Life science

Publications

  • Andersen, Thorny Cesilie Bie; Kristiansen, Per Eugen; Huszenicza, Zsuzsa; Johansson, Maria U.; Gopalakrishnan, Ramakrishna Prabhu; Kjelstrup, Hanna; Boyken, Scott; Gjerstad, Vibeke Sundvold; Granum, Stine; Sørli, Morten; Backe, Paul Hoff; Fulton, Bruce D; Karlsson, B.Göran; Andreotti, Amy H. & Spurkland, Anne (2019). The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell?specific adapter protein. Journal of Biological Chemistry.  ISSN 0021-9258.  294(42), s 15480- 15494 . doi: 10.1074/jbc.RA119.008318
  • Abrahamsen, Greger; Gjerstad, Vibeke Sundvold; Mekonnen, Meseret; Bogen, Bjarne & Spurkland, Anne (2018). Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd. Scientific Reports.  ISSN 2045-2322.  8:13319, s 1- 13 . doi: 10.1038/s41598-018-31510-6 Full text in Research Archive.
  • Mekonnen, Meseret Habtamu; Abebe, Markos; Aseffa, Abraham; Dyrhol-Riise, Anne Ma; Spurkland, Anne & Abrahamsen, Greger (2018). In vitro analysis of antigen induced T cell-monocyte conjugates by imaging flow cytometry. JIM - Journal of Immunological Methods.  ISSN 0022-1759.  460, s 93- 100 . doi: 10.1016/j.jim.2018.06.014 Full text in Research Archive.
  • Mitrovic, Mitja; Patsopoulos, Nikolaos A.; Beecham, Ashley H.; Dankowski, Theresa; Goris, An; Dubois, Benedicte; D’hooghe, Marie B.; Lemmens, Robin; Van Damme, Philip; Bach Søndergaard, Helle; Sellebjerg, Finn; Soelberg Sorensen, Per; Ullum, Henrik; Thørner, Lise Wegner; Werge, Thomas; Saarela, Janna; Cournu-Rebeix, Isabelle; Damotte, Vincent; Fontaine, Bertrand; Guillot-Noel, Lena; Lathrop, Mark; Vukusik, Sandra; Gourraud, Pierre-Antoine; Andlauer, Till F.M.; Pongratz, Viola; Buck, Dorothea; Gasperi, Christiane; Antonios, Bayas; Heesen, Christoph; Kümpfel, Tania; Linker, Ralf; Paul, Friedemann; Stangel, Martin; Tackenberg, Björn; Bergh, Florian Then; Warnke, Clemens; Wiendl, Heinz; Wildemann, Brigitte; Zettl, Uwe; Ziemann, Ulf; Tumani, Hayrettin; Gold, Ralf; Grummel, Verena; Hemmer, Bernhard; Knier, Benjamin; Lill, Christina M.; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Lie, Benedicte Alexandra; Spurkland, Anne; Harbo, Hanne Flinstad & Cotsapas, Chris (2018). Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk. Cell.  ISSN 0092-8674.  175(6), s 1679- 1687 . doi: 10.1016/j.cell.2018.09.049
  • Hem, Cecilie Anne Dahl; Ekornhol, Marianne; Granum, Stine; Gjerstad, Vibeke Sundvold & Spurkland, Anne (2017). CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein. Scandinavian Journal of Immunology.  ISSN 0300-9475.  85(2), s 104- 112 . doi: 10.1111/sji.12513
  • Berge, Tone; Leikfoss, Ingvild Sørum; Brorson, Ina Skaara; Bos, Steffan Daniel; Page, Christian; Gustavsen, Marte Wendel; Bjølgerud, Anja; Holmøy, Trygve; Celius, Elisabeth Gulowsen; Damoiseaux, J.; Smolders, J; Harbo, Hanne Flinstad & Spurkland, Anne (2016). The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by Vitamin D in CD4+ T cells. Genes and Immunity.  ISSN 1466-4879.  17(2), s 118- 127 . doi: 10.1038/gene.2015.61
  • Gordon, Emma; Fukuhara, D.; Weström, S.; Padhan, N.; Sjöström, Elisabeth; van Meeteren, L.; He, Liqun; Orsenigo, F.; Dejana, E.; Bentley, K.; Spurkland, Anne & Claesson-Welsh, Lena (2016). The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation. Science Signaling.  ISSN 1945-0877.  9(437) . doi: 10.1126/scisignal.aad9256
  • Enqvist, Monika; Ask, Eivind Heggernes; Forslund, Elin; Carlsten, Mattias; Abrahamsen, Greger; Béziat, Vivien; Andersson, Sandra; Schaffer, Marie; Spurkland, Anne; Bryceson, Yenan; Önfelt, Björn & Malmberg, Karl-Johan (2015). Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. Journal of Immunology.  ISSN 0022-1767.  194(9), s 4518- 4527 . doi: 10.4049/jimmunol.1401972
  • Eriksen, Agnete Bratsberg; Berge, Tone; Gustavsen, Marte Wendel; Leikfoss, Ingvild Sørum; Bos, Steffan Daniel; Spurkland, Anne; Harbo, Hanne Flinstad & Blomhoff, Heidi Kiil (2015). Retinoic acid enhances the levelels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  278, s 11- 18 . doi: 10.1016/j.jneuroim.2014.11.019
  • Eriksen, Agnete Bratsberg; Torgersen, Maria Lyngaas; Lillebø Holm, Kristine; Abrahamsen, Greger; Spurkland, Anne; Moskaug, Jan Øivind; Simonsen, Anne & Blomhoff, Heidi Kiil (2015). Retinoic acid-induced IgG Production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy.  ISSN 1554-8627.  11(3), s 460- 471 . doi: 10.1080/15548627.2015.1009797
  • Hem, Cecilie Anne Dahl; Gjerstad, Vibeke Sundvold; Granum, Stine; Koll, Lise; Abrahamsen, Greger; Buday, Laszlo & Spurkland, Anne (2015). T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells. Cell Communication and Signaling.  ISSN 1478-811X.  13(1) . doi: 10.1186/s12964-015-0109-7
  • Leikfoss, Ingvild Sørum; Keshari, Pankaj Kumar; Gustavsen, Marte Wendel; Bjølgerud, Anja; Brorson, Ina Skaara; Celius, Elisabeth Gulowsen; Spurkland, Anne; Bos, Steffan Daniel; Harbo, Hanne Flinstad & Berge, Tone (2015). Multiple sclerosis risk allele in CLEC16A acts as an expression quantitative trait locus for CLEC16A and SOCS1 in CD4+ T cells. PLOS ONE.  ISSN 1932-6203.  10>e0132957(7) . doi: 10.1371/journal.pone.0132957 Full text in Research Archive.
  • Moussa, P; Abrahamsen, Greger; Fodil, N; Gopalakrishnan, Ramakrishna Prabhu; Mancini, M; Dissen, Erik; Sæther, Per Christian; Wiltshire, SA; Boivin, GA; Caignard, G; Spurkland, Anne & Vidal, SM (2015). Reduced MCMV Δm157 viral clearance in the absence of TSAd. Scientific Reports.  ISSN 2045-2322.  5 . doi: 10.1038/srep09219 Full text in Research Archive.
  • Moutsianas, Loukas; Jostins, Luke; Beecham, Ashley H.; Dilthey, Alexander T.; Xifara, Dionysia K.; Ban, Maria; Shah, Tejas S.; Patsopoulos, Nikolaos A.; Alfredsson, Lars; Anderson, Carl A.; Attfield, Katherine E.; Baranzini, Sergio E.; Barrett, Jeffrey; Binder, Thomas M.C.; Booth, David; Buck, Dorothea; Celius, Elisabeth Gulowsen; Cotsapas, Chris; D'Alfonso, Sandra; Dendrou, Calliope A.; Donnelly, Peter; Dubois, Bénédicte; Fontaine, Bertrand; Fugger, Lars; Goris, An; Gourraud, Pierr-Antoine; Graetz, Christiane; Hemmer, Bernhard; Hillert, Jan; Kockum, Ingrid; Leslie, Stephen; Lill, Christina M.; Martinelli-Boneschi, Filippo; Oksenberg, Jorge R.; Olsson, Tomas; Oturai, Annette; Saarela, Janna; Søndergaard, Helle Bach; Spurkland, Anne; Taylor, Bruce; Winkelmann, Juliane; Zipp, Frauke; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Spencer, Chris C.A.; Stewart, Graeme; Hafler, David A; Ivinson, Adrian J.; Harbo, Hanne Flinstad; Hauser, Stephen L.; De Jager, Philip L.; Compston, Alastair; McCauley, Jacob L.; Sawcer, Stephen & McVean, Gil (2015). Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics.  ISSN 1061-4036.  47(10), s 1107- 1113 . doi: 10.1038/ng.3395
  • Andersen, Thorny Cesilie Bie; Lindsjø, Kjersti; Hem, Cecilie Anne Dahl; Koll, Lise; Kristiansen, Per Eugen; Skjeldal, Lars; Andreotti, Amy H. & Spurkland, Anne (2014). Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO. BMC Biotechnology.  ISSN 1472-6750.  14(3) . doi: 10.1186/1472-6750-14-3 Full text in Research Archive.
  • Damotte, V; Guillot-Noel, Lena; Patsopoulos, Nikolaos A.; Madireddy, L; Behi, M El; Ban, Maria; Baranzini, Sergio; Barcellos, Lisa; Beecham, Gary; Beecham, Ashley; Bernardinelli, L; Booth, David; Bos, Steffan Daniel; Buck, Dorothea; Bush, William; Comabella, Manuel; Compston, Alastair; Cotsapas, Chris; Cournu-rebeixisabelle, Isabelle; Cree, Bruce; d'Alfonso, Sandra; Daly, Mark; Damotte, Vincent; Davis, Mary; Bakker, Paul de; De Jager, Philip L; Dubois, Benedicte; Esposito, Federica; Fontaine, Bertrand; Goris, An; Gourraud, Pierre-Antoine; Green, Todd; Celius, Elisabeth Gulowsen; Hadjixenofontos, Athena; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen; Hawkins, Clive; Hemmer, Bernhard; Hillert, Jan; Hintzen, Rogier; Horáková, Dana; Ivinson, Adrian J; Kemppinen, Anu; Kira, Jun-ichi; Kockum, Ingrid; Lincoln, Robin; Martin, Roland; Boneschi, Filippo martinelli; McCauley, Jacob L.; Mero, Inger-Lise; Oksenberg, Jorge; Olsson, Tomas; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret; Rioux, John; Saarela, Janna; Sawcer, Stephen; Schnetz-boutaud, Nathalie; Sellebjerg, Finn; Soendergaard, Helle; Sorensen, Per Soelberg; Spurkland, Anne; Stankovich, Jim; Stewart, Graeme; Taylor, Bruce; Ticca, Anna; West, Sandra; Zipp, Frauke; Blackwell, Jenefer m; Bramon, Elvira; Brown, Matthew A; Casas, Juan Pablo; Corvin, Aiden; Jankowski, Janusz; Markus, Hugh s; Mathew, Christopher G.; Palmer, Colin NA; Plomin, Robert; Rautanen, Anna; Trembath, Richard c; Viswanathan, Ananth c; Wood, Nicholas W.; Spencer, Chris ca; Band, Gavin; Bellenguez, Celine; Freeman, Colin; Hellenthal, Garrett; Giannoulatou, Eleni; Pirinen, Matti; Pearson, Richard; Strange, Amy; Su, Zhan; Vukcevic, Damjan; Donnelly, Peter; Langford, Cordelia; Hunt, Sarah E; Edkins, Sarah; Gwilliam, Rhian; Blackburn, Hannah; Bumpstead, Suzannah J.; Dronov, Serge; Gillman, Matthew; Gray, Emma; Hammond, Naomi; Jayakumar, Alagurevathi; Mccann, Owen t; Liddle, Jennifer; Potter, Simon C; Ravindrarajah, Rathi; Ricketts, Michelle; Waller, Matthew J; Weston, Paul; Widaa, Sara; Whittaker, Pamela; Barroso, Ines; Deloukas, Panos; Dilthey, Alexander; Leslie, Stephen; Moutsianas, Loukas; Perez, Marc l; Mcvean, Gil; Mccarthy, Mark i; Baranzini, SE; Cournu-Rebeix, I & Fontaine, B. (2014). A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes and Immunity.  ISSN 1466-4879.  15, s 126- 132 . doi: 10.1038/gene.2013.70
  • Goris, An; Van Setten, Jessica; Diekstra, Frank; Ripke, Stephan; Patsopoulos, Nikolaos A.; Sawcer, Stephen; Ban, Maria; Baranzini, Sergio; Barcellos, Lisa; Beecham, Gary; Beecham, Ashley; Bernardinelli, L; Booth, David; Bos, Steffan Daniel; Buck, Dorothea; Bush, William; Comabella, Manuel; Compston, Alastair; Cotsapas, Chris; Cournu-Rebeix, Isabelle; Cree, Bruce; d'Alfonso, Sandra; Daly, Mark; Damotte, Vincent; Davis, Mary; Bakker, Paul de; De Jager, Philip L; Dubois, Benedicte; Esposito, Federica; Fontaine, Bertrand; Gourraud, Pierre-Antoine; Green, Todd; Celius, Elisabeth Gulowsen; Hadjixenofontos, Athena; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen; Hawkins, Clive; Hemmer, Bernhard; Hillert, Jan; Hintzen, Rogier; Horáková, Dana; Ivinson, Adrian J; Kemppinen, Anu; Kira, Jun-ichi; Kockum, Ingrid; Lincoln, Robin; Martin, Roland; Boneschi, Filippo martinelli; McCauley, Jacob L.; Mero, Inger-Lise; Oksenberg, Jorge; Olsson, Tomas; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret; Rioux, John; Saarela, Janna; Schnetz-boutaud, Nathalie; Sellebjerg, Finn; Soendergaard, Helle; Sorensen, Per Soelberg; Spurkland, Anne; Stankovich, Jim; Stewart, Graeme; Taylor, Bruce; Ticca, Anna; West, Sandra; Zipp, Frauke; van Es, Michael; Bahlo, M; Booth, DR; Broadley, SA; Brown, MA; Foote, SJ; Griffiths, LR; Kilpatrick, TJ; Lechner-Scott, J; Moscato, P; Perreau, VM; Rubio, JP; Scott, RJ; Stankovich, J; Taylor, BV; Wiley, J; Clarke, G; Cox, MB; Csurhes, PA; Danoy, P; Drysdale, K; Field, J; Greer, JM; Guru, P; Hadler, J; Mcmorran, BJ; Jensen, CJ; Johnson, JL; McCallum, R.; Merriman, M.; Merriman, T.; Pryce, K; Stewart, GJ; Tajouri, L; Wilkins, EJ; Browning, BL; Browning, SR; Perera, D; Broadley, S.; Butzkueven, H.; Carroll, WM; Chapman, C.; Kermode, AG; Marriott, M; Mason, D; Heard, RN; Pender, MP; Slee, M.; Tubridy, N; Willoughby, E; Andersen, Peter M.; Melki, Judith; Meininger, Vincent; Hardiman, Orla; Landers, John E; Brown, Robert H; Shatunov, Aleksey; Leigh, Nigel; Al-Chalabi, Ammar; Shaw, Christopher E; Traynor, Bryan J.; Chio, Adriano; Restagno, Gabriella; Mora, Gabriele; Ophoff, Roel A.; Oksenberg, Jorge R.; Van Damme, Philip; Robberecht, Wim; van den Berg, Leonard H.; Veldink, Jan H & de Bakker, Paul I.W. (2014). No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Human Molecular Genetics.  ISSN 0964-6906.  23(7), s 1916- 1922 . doi: 10.1093/hmg/ddt574
  • Granum, Stine; Gjerstad, Vibeke Sundvold; Gopalakrishnan, Ramakrishna Prabhu; Berge, Tone; Koll, Lise; Abrahamsen, Greger; Sørlie, Morten & Spurkland, Anne (2014). The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. Science Signaling.  ISSN 1945-0877.  7:ra118(355) . doi: 10.1126/scisignal.2005384
  • Pandya, Abhilash D.; Leergaard, Trygve Brauns; Dissen, Erik; Haraldsen, Guttorm & Spurkland, Anne (2014). Expression of the T cell-specific adapter protein in human tissues. Scandinavian Journal of Immunology.  ISSN 0300-9475.  80(3), s 169- 179 . doi: 10.1111/sji.12199
  • Sundqvist, Emilie; Buck, Dorothea; Warnke, Clemens; Albrecht, Eva; Gieger, Christian; Khademi, Mohsen; Lima Bomfim, Izaura; Fogdell-Hahn, Anna; Link, Jenny; Alfredsson, Lars; Søndergaard, Helle Bach; Hillert, Jan; Barcellos, Lisa; Booth, David; McCauley, Jacob L.; Comabella, Manuel; Compston, Alastair; d'Alfonso, Sandra; de Jager, Philip; Fontaine, Bertrand; Goris, An; Hafler, David; Haines, Jonathan; Harbo, Hanne Flinstad; Hauser, Stephen L; Hawkins, Clive; Ivinson, Adrian; Martin, Roland; Boneschi, Fillippo Martinelli; Oksenberg, Jorge; Patsopoulos, Nikolaos; Pericak-Vance, Margaret; Saarela, Janna; Sawcer, Stephen; Spurkland, Anne; Stewart, Graeme; Zipp, Frauke; Oturai, Annette B.; Hemmer, Bernhard; Kockum, Ingrid & Olsson, Tomas (2014). JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants. PLoS Pathogens.  ISSN 1553-7366.  10(4) . doi: 10.1371/journal.ppat.1004084
  • Baranzini, SE; Celius, E.G.; Elovaara, I; Harbo, HF; Hillert, J; Myhr, Kjell-Morten; Sørensen, PS; Spurkland, A; Sawcer, S; Hauser, SL; Oksenberg, JR; Khankhanian, Pouya; Patsopoulos, Nikolaos A.; Li, Michael; Stankovich, Jim; Cotsapas, Chris; Søndergaard, Helle Bach; Ban, Maria; Barizzone, Nadia; Bergamaschi, Laura; Booth, David; Buck, Dorothea; Cavalla, Paola; Celius, Elisabeth G.; Comabella, Manuel; Comi, Giancarlo; Compston, Alastair; Cournu-Rebeix, Isabelle; D’alfonso, Sandra; Damotte, Vincent; Din, Lennox; Dubois, Benedicte; Elovaara, Irina; Esposito, Federica; Fontaine, Bertrand; Franke, Andre; Goris, An; Gourraud, Pierre-Antoine; Graetz, Christiane; Guerini, Franca R.; Guillot-Noel, Lena; Hafler, David A; Hakonarson, Hakon; Hall, Per; Hamsten, Anders; Harbo, Hanne Flinstad; Bernhard, Hemmer; Hillert, Jan; Kemppinen, Anu; Ingrid, Kockum; Koivisto, Keijo; Larsson, Malin; Lathrop, Mark; Leone, Maurizio; Lill, Christina M.; Macciardi, Fabio; Martin, Roland; Martinelli, Vittorio; Martinelli-Boneschi, Filippo; McCauley, Jacob L.; Naldi, Paoloa; Olsson, Tomas; Oturai, Annette; Pericak-Vance, Margaret A.; Perla, Franco; Reunanen, Mauri; Saarela, Janna; Saker-Delye, Safa; Salvetti, Marco; Sellebjerg, Finn; Sørensen, Per Soelberg; Spurkland, Anne; Stewart, Graeme; Taylor, Bruce; Tienari, Pentti; Winkelmann, Juliane; Wellcome Trust Case Control, Consortium 2; Zipp, Frauke; Ivinson, Adrian J; Haines, Jonathan L.; Sawcer, Stephen; DeJager, Philip; Hauser, Stephen L & Oksenberg, Jorge R. (2013). Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls. American Journal of Human Genetics.  ISSN 0002-9297.  s 854- 865 . doi: 10.1016/j.ajhg.2013.04.019
  • Beecham, Ashley H.; Patsopoulos, NA; Xifara, DK; Davis, MF; Kemppinen, A; Cotsapas, C; Shah, TS; Spencer, C; Booth, D; Goris, A; Oturai, A; Saarela, J; Fontaine, B; Hemmer, B; Martin, C; Zipp, F; D'Alfonso, S; Martinelli-Boneschi, F; Taylor, B; Harbo, Hanne Flinstad; Kockum, I; Hillert, J; Olsson, T; Ban, M; Oksenberg, JR; Hintzen, R; Barcellos, LF; Agliardi, C; Alfredsson, L; Alizadeh, M; Anderson, C; Andrews, R; Sondergaard, HB; Baker, A; Band, G; Baranzini, SE; Barizzone, N; Barrett, J; Bellenguez, C; Bergamaschi, L; Bernardinelli, L; Berthele, A; Biberacher, V; Binder, TMC; Blackburn, H; Bomfim, IL; Brambilla, P; Broadley, S; Brochet, B; Brundin, L; Buck, D; Butzkueven, H; Caillier, SJ; Camu, W; Carpentier, W; Cavalla, P; Celius, Elisabeth Gulowsen; Coman, I; Comi, G; Corrado, L; Cosemans, L; Cournu-Rebeix, I; Cree, BAC; Cusi, D; Damotte, V; Defer, G; Delgado, SR; Deloukas, P; di Sapio, A; Dilthey, AT; Donnelly, P; Dubois, B; Duddy, M; Edkins, S; Elovaara, I; Esposito, F; Evangelou, N; Fiddes, B; Field, J; Franke, A; Freeman, C; Frohlich, IY; Galimberti, D; Gieger, C; Gourraud, PA; Graetz, C; Graham, A; Grummel, V; Guaschino, C; Hadjixenofontos, A; Hakonarson, H; Halfpenny, C; Hall, G; Hall, P; Hamsten, A; Harley, J; Harrower, T; Hawkins, C; Hellenthal, G; Hillier, C; Hobart, J; Hoshi, M; Hunt, SE; Jagodic, M; Jelcic, I; Jochim, A; Kendall, B; Kermode, A; Kilpatrick, T; Koivisto, K; Konidari, I; Korn, T; Kronsbein, H; Langford, C; Larsson, M; Lathrop, M; Lebrun-Frenay, C; Lechner-Scott, J; Lee, MH; Leone, MA; Leppa, V; Liberatore, G; Lie, Benedicte Alexandra; Lill, CM; Linden, M; Link, J; Luessi, F; Lycke, J; Macciardi, F; Mannisto, S; Manrique, CP; Martin, R; Martinelli, V; Mason, D; Mazibrada, G; McCabe, C; Mero, Inger-Lise; Mescheriakova, J; Moutsianas, L; Myhr, Kjell-Morten; Nagels, G; Nicholas, R; Nilsson, P; Piehl, F; Pirinen, M; Price, SE; Quach, H; Reunanen, M; Robberecht, W; Robertson, NP; Rodegher, M; Rog, D; Salvetti, M; Schnetz-Boutaud, NC; Sellebjerg, F; Selter, RC; Schaefer, C; Shaunak, S; Shen, L; Shields, S; Siffrin, V; Slee, M; Sorensen, PS; Sorosina, M; Sospedra, M; Spurkland, Anne; Strange, A; Sundqvist, E; Thijs, V; Thorpe, J; Ticca, A; Tienari, P; van Duijn, C; Visser, EM; Vucic, S; Westerlind, H; Wiley, JS; Wilkins, A; Wilson, JF; Winkelmann, J; Zajicek, J; Zindler, E; Haines, JL; Pericak-Vance, MA; Ivinson, AJ; Stewart, G; Hafler, D; Hauser, SL; Compston, A; McVean, G; De Jager, P; Sawcer, SJ & McCauley, JL (2013). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics.  ISSN 1061-4036.  45(11), s 1353- 1360 . doi: 10.1038/ng.2770
  • Jacobsen, Johanne Tracey; Gjerstad, Vibeke Sundvold; Skjeldal, Frode Miltzow; Andersen, Jan Terje; Abrahamsen, Greger; Bakke, Oddmund; Spurkland, Anne & Bogen, Bjarne (2013). B-cell tolerance to the B-cell receptor variable regions. European Journal of Immunology.  ISSN 0014-2980.  43(10), s 2577- 2587 . doi: 10.1002/eji.201243203
  • Leikfoss, Ingvild Sørum; Mero, Inger-Lise; Dahle, Maria Krudtaa; Lie, Benedicte Alexandra; Harbo, Hanne Flinstad; Spurkland, Anne & Berge, Tone (2013). Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus. Genes and Immunity.  ISSN 1466-4879.  14(1), s 62- 66 . doi: 10.1038/gene.2012.52
  • Rosella, Mechelli; Renato, Umeton; Policano, Claudia; Annibali, Viviana; Giulia, Coarelli; Ricigliano, Vito A. G.; Vittori, Danila; Fornasiero, Arianna; Buscarinu, Maria Chiara; Sawcer, Stephen; Hellenthal, Garrett; Pirinen, Matti; Spencer, Chris C A; Patsopoulos, Nikolaos; Mousianas, Loukas; Dithey, Alexander; Su, Zhan; Freeman, Colin; Hunt, Sarah E; Edkins, Sarah; Gray, Emma; Booth, David R; Potter, Simon C; Goris, An; Band, Gavin; Oturai, Annette Bang; Strange, Amy; Saarela, Janna; Bellenguez, Celine; Fontaine, Bertrand; Gillman, Matthew; Hemmer, Bernhard; Gwilliam, Rhian; Zipp, Frauke; Jayakumar, Akagurevathi; Martin, Roland; Leslie, Stephen; Hawkins, Stanley; Giannolatou, Eleni; D`alfonso, Sandra; Blackburn, Hannah; Boneschi, Fillippo Martinelli; Liddle, Jennifer; Harbo, Hanne Flinstad; Perez, Marc L; Spurkland, Anne; Waller, Matthew J; Mycko, Marcin P; Ricketts, Michelle; Comabella, Manuel; Celius, Elisabeth Gulowsen; Lorentzen, Åslaug Rudjord; Mero, Inger-Lise; Myhr, Kjell-Morten & SMESTAD, CATHRINE (2013). A ‘‘candidate-interactome’’ aggregate analysis of genome-wide association data in multiple sclerosis. PLOS ONE.  ISSN 1932-6203.  8(5) . doi: 10.1371/journal.pone.0063300
  • Berge, Tone; Grønningsæter, Ingrid Helene; Lorvik, Kristina Berg; Abrahamsen, Greger; Granum, Stine; Gjerstad, Vibeke Sundvold; Corthay, Alexandre; Bogen, Bjarne & Spurkland, Anne (2012). SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice. PLOS ONE.  ISSN 1932-6203.  7(10)

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  • Spurkland, Anne (2017). Immun. Kroppens evige kamp for å overleve. Spartacus.  ISBN 9788243008304.  416 s.

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  • Consortium, International MS genetics; Bos-Haugen, Steffan Daniël; Harbo, Hanne Flinstad; Celius, Elisabeth Gulowsen & Spurkland, Anne (2019). Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.. Science.  ISSN 0036-8075. . doi: 10.1126/science.aav7188
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.
  • Spurkland, Anne (2018). Den døde kroppen. Syn og Segn.  ISSN 0039-7717.  (3) Show summary
  • Sundbye, Bodil; Hauge, Siri Helene; Spurkland, Anne; Blomberg, Bjørn & Ørmen, Torfinn (2018, 05. august). Epidemiene som truer verden.  Verdens Gang.
  • Borowicz, Pawel; Gopalakrishnan, Ramakrishna Prabhu; De Souza, Gustavo Antonio; Abrahamsen, Greger; Sundvold-Gjerstad, Vibeke & Spurkland, Anne (2017). The interactome of TSAd phosphopeptides in T cells.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna & Spurkland, Anne (2017). The regulatory role of Lck Tyr192 in T cell receptor signalling.
  • Borowicz, Pawel & Spurkland, Anne (2016). Intracellular signaling in CRISPR mutated Jurkat T cells.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger & Spurkland, Anne (2016). Generation of CRISPR/Cas9 mutants in order to study TCR signalling pathway.
  • Spurkland, Anne (2016). Gjenkjent. Show summary
  • Spurkland, Anne (2016). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Spurkland, Anne (2016). Multiple sclerosis genetics.
  • Spurkland, Anne (2016). Regulation of Lck specificity in TCR signal initiation.
  • Spurkland, Anne (2016). Skam. Show summary
  • Spurkland, Anne (2016). Skamløs?. Show summary
  • Spurkland, Anne (2016, 25. mars). Slik virker immunforsvarets hukommelse. [Internett].  Forskning.no.
  • Spurkland, Anne (2013). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Spurkland, Anne (2013). Immunforsvaret. Kroppens evige kamp for å overleve.
  • Tilset, Mats; Boye, Erik & Spurkland, Anne (2013). Glemte sykdommer rammer 1 milliard. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Berge, Tone; Leikfoss, Ingvild Sørum; Spurkland, Anne; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2012). Multiple sclerosis-associated single nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in thymic tissue.
  • Leikfoss, Ingvild S; Mero, Inger-Lise; Dahle, Maria Krudtaa; Lie, Benedicte Alexandra; Harbo, Hanne Flinstad; Spurkland, Anne & Berge, Tone (2012). Multiple Sclerosis Associated Single Nucleotide Polymorphisms in CLEC16A Correlate with Reduced SOCS1 and DEXI Expression in Thymic Samples. Scandinavian Journal of Immunology.  ISSN 0300-9475.  76(2), s 196- 196
  • Leikfoss, Ingvild Sørum; Berge, Tone; Harbo, Hanne Flinstad & Spurkland, Anne (2012). Multiple sclerosis-associated single nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in thymic tissue.

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Published Apr. 13, 2011 2:40 PM - Last modified Nov. 17, 2019 10:46 AM