Gareth Sullivan

Researcher
Image of Gareth Sullivan
Phone 22851415
Username
Visiting address Sognsvannsveien 9 0372 OSLO
Postal address Postboks 1110 Blindern 0317 OSLO
Tags: Stem Cells, Pluripotent Stem cells, Organoids, Disease Modeling, Differentiation, Endoderm

Publications

 

  • Tanaka Y, Cakir B, XiangY, Sullivan GJand Park IH. Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain. Cell Reports 2020:doi.org/10.1016/j.celrep.2020.01.038

  • Bogdanova M, Kostina A, Enayati  KZ, Zabirnyk A, Malashicheva A, Stensløkken KO, Sullivan G, Kaljusto ML, John-Peder Kvitting JPE, Kostareva A, Vaage J, Rutkovskiy A. Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells. Frontiers in Physiology2018|:doi:10.3389/fphys.2018.01635

  • Kim KY, Tanaka Y, Su J, Cakir  B, Xiang Y, Patterson B, Ding JJ, Jung YW, Kim JH, Hysolli E, Lee H, Dajani R, Kim J, Zhong M, Lee JH, Skalnik D, Lim JM, Sullivan GJ, Wang J, and Park IH. Active transcription regulation by Uhrf1 is essential for bivalent modification in pluripotency. Nature Communications 2018:9:2583 | DOI: 10.1038/s41467-018-04818-0.

  • Pisal RV, Suchanek J, Hrebikova H, Bezrou A, Soukup T, Kunke D, Micuda S, Filip S, Siller R, Sullivan GJ and Mokry J. Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth.  (2018):Scientific Reports. Apr 18;8(1):6168.

  • Siller R and Sullivan GJ*. Simple and rapid screen for human pluripotent stem cell endoderm differentiation potential. Current Protocols in Stem Cell Biology, (2017): 43, 1G.7.1–1G.7.23.doi: 10.1002/cpsc.36. (*corresponding author).

  • Rutkovskiy A, Malashicheva A, Sullivan GJ*, Bogdanova M, Kostareva A, Stensløkken KO, Fianne A, Vaage J. Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification. Journal of the American Heart Association. (2017): 14;6(9) pii: e006339. doi: 10.1161/JAHA.117.006339.(*co-corresponding author).

  • Scarfe L, Brillant N, Kumar JD, Ali N, Alrumayh A, Amali M, Barbellion S and et al. Pre-clinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. Nature Regenerative Medicine. (2017): (2017)2:28; doi:10.1038/s41536-017-0029-9.

  • Siller R, Greenhough S, Mathipati S, Si-Tayeb K* and Sullivan GJ*. Future challenges in the generation of hepatocyte like cells from human pluripotent stem cells. Current Pathobiology Reports. (2017):5:(3):301-314. (*co-corresponding author).

  • Siller R, Dufour E, Wilmut I, Jung Y-W, Park IH and Sullivan GJ*. Development of an inducible platform for intercellular protein delivery. International Journal of Pharmaceutics. (2017): http://dx.doi.org/10.1016/j.ijpharm.2017.02.067. (*corresponding author).

  • Gamal W, Treskes P, Chesne CG, Samuel K, Sullivan GJ, Siller R, Srsen V, Underwood I, Smith S, Hayes PC, Plevris JN, Bagnaninchi PO and Nelson LJ. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Scientific Reports. (2017):DOI: 10.1038/srep37541.

  • Siller R, Naumovska E, Mathapati S, Lycke M and Sullivan GJ*. Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines. Scientific Reports. (2016):DOI: 10.1038/srep37178. (*corresponding author).   

  • Mathapati S, Siller R, Impellizzeri AR, Lycke M, Vegheim K, Almass R and Sullivan GJ*. Small molecule directed hepatocytes like cells differentiation of human pluripotent stem cells. Curr. Protoc. Stem Cell Biol. (2016): 38:1G.6.1-1G.6.18.doi: 10.1002/cpsc.13. (*corresponding author).   

  • Xu M, Stattin E-L, Shaw G, Heinegård D, Sullivan G, Wilmut I, Colman A, Önnerfjord P, Khabut A, Aspberg A, Dockery P, Hardingham T, Murphy M, Barry F. Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an ER stress response and defective matrix assembly. Stem Cells Transl. Med. (2016): 5:1171-1181.

  • Siller R, Greenhough S, Naumovska E and Sullivan GJ*. Small molecule driven hepatocyte differentiation of human pluripotent stem cells. Stem Cell Reports. (2015): 4:939-952. (*corresponding author).     

  • Siller R, Greenhough S, Park IH and Sullivan GJ*. (2013) Modelling human disease with pluripotent stem cells. Current Gene Therapy. 13(2):99-110. (*corresponding author).   

  • Dajani R, Koo SE, Sullivan GJ*, Park IH. (2013) Investigation of Rett syndrome using pluripotent stem cells. J Cell Biochem. 114:2446-2453 (*corresponding author).  

  • Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. (2013) Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".  Sci Transl Med. 5(188):188le2.

  • Kim KY, Jung YW, Sullivan GJ, Chung L and Park IH. Cellular Reprogramming: a novel tool in investigating ASDs. Trends Mol Med 2012;18:463-71.

  • Yamazaki T, Chen S, Yu Y, Yan B, Carrasco MA, Tapia JC, Zhai B, Das R, Lalancette-Hebert M, Sharma A, Chandran S, Sullivan G, Nishimura AL, Shaw CE, Gygi SP, Shneider NA, Maniatis T, and Reed R. FUS-SMN protein interactions link the motor neuron diseases ALS and SMA. Cell Rep. 2012;25;2:799-806. F1000 recommended.

  • Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.   Proc Natl Acad Sci USA 2012;109:5803-8. F1000 recommended.

  • Zhou XL, Sullivan GJ, Sun P, and Park IH. Humanized murine model for HBV and HCV using human induced pluripotent stem cells. Archives of Pharmacal Research. 2012;35(2):261-269.

  • Hysolli E, Zhou XL, Liu R, Kim JH, Adams B, Sullivan GJ, and Park IH. Role of Pluripotent Stem Cells in Regenerative Medicine. Regenerative Medicine, Stem Cells and the Liver. Book Chapter, March 15, (2012) by Science Publishers.

  • Wilmut I, Sullivan G and Chambers I. (2011).  The evolving biology of cell reprogramming. Philosophical Transactions of the Royal Society B. Philosophical Transactions of the Royal Society B 366:2183-2197.

  • Wilmut I,  Wongtawan T, Quigley M and Sullivan GJ.  Biomedical and social contributions to sustainability. Philosophical Transactions of the Royal Society A. 2011;369:1730-1747.

  • Ruzov A,  Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan GJ, Chandran S, Hay D, Bradley M, Wilmut I and De Sousa P. (2011) Lineage specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development. Cell Research. 21:1332-42.

  • Sullivan GJ, Bai YM, Fletcher J and Wilmut I. (2010) Induced pluripotent stem cells: epigenetic memories and practical implications.  Molecular Human Reproduction 16:880–885.

  • Hannoun Z, Filippi C, Sullivan GJ, Hay DC and Iredale JP. (2010) Hepatic Endoderm Differentiation from Human Embryonic Stem Cells. Current Stem Cell Research &Therapy  5:233-244.

  • Sullivan GJ*, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross JA, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, Iredale JP and Wilmut I. (2010) Efficient Generation of iPSC-Derived Human Hepatic Endoderm Displaying Liver Specific Metabolism. Hepatology 51:329-335. (*corresponding author). F1000 recommended. Editiorial Hepatology and Press coverage BBC.

  • Taylor J, Wilmut I, Sullivan GJ.  What are the limits to cell plasticity? [Research Highlight] Cell Research. 2010;20:502-503.

  • Wilmut I, Sullivan GJ and Taylor J. A decade of progress since the birth of Dolly. Reproduction, Fertility and Development. 2009;21, 95–100.

  • O’Sullivan A, Sullivan GJ and McStay B.  UBF binding in vivo is not restricted to regulatory sequences within the vertebrate rDNA repeat.  MCB 2002;22(2); 657-668

  • Sullivan GJ, Bridger JM, Cuthbert AP, Newbold RF, Bickmore WA, McStay B.  Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli. EMBO J. 2001;20(11):2867-74.

  • Sullivan GJ, McStay B.  Dimerization and HMG box domains 1-3 present in Xenopus UBF are sufficient for its role in transcriptional enhancement. Nucleic Acids Res. 1998;26(15):3555-61.

  • McStay B, Sullivan GJ, Cairns C.  The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter. EMBO J. 1997; 16(2):396-405.

  • Woodward MJ, Sullivan GJ.     Nucleotide sequence of a repetitive element isolated from Leptospira interrogans serovar hardjo type hardjo-bovis. J Gen Microbiol. 1991;137:1101-9.

  • Woodward MJ, Sullivan GJ, Palmer NM, Woolley JC, Redstone JS.  Development of a PCR test specific for Leptospira hardjo genotype bovis. Vet Rec. 1991;128(12):282-3.

  • Book Chapters
  • Hysolli E, Zhou XL, Liu R, Kim JH, Adams B, Sullivan GJ, and Park IH. Role of Pluripotent Stem Cells in Regenerative Medicine. Regenerative Medicine, Stem Cells and the Liver. Book Chapter, March 15, (2012) by Science Publishers.
  • Bogdanova, Mariia; Zabirnyk, Arsenii; Malashicheva, Anna; Semenova, Daria; Escobar Kvitting, John-Peder & Kaljusto, Mari-Liis [Show all 12 contributors for this article] (2022). Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview. Frontiers in Pharmacology. ISSN 1663-9812. 13. doi: 10.3389/fphar.2022.835825.
  • Kristiansen, Cecilie Katrin; Chen, Anbin; Høyland, Lena Elise; Ziegler, Mathias; Sullivan, Gareth John & Bindoff, Laurence Albert [Show all 7 contributors for this article] (2022). Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations. Cell Cycle. ISSN 1538-4101. 21(20), p. 2206–2221. doi: 10.1080/15384101.2022.2092185.
  • Chen, Anbin; Kristiansen, Cecilie Katrin; Høyland, Lena Elise; Ziegler, Mathias; Wang, Jian & Sullivan, Gareth John [Show all 9 contributors for this article] (2022). POLG mutations lead to abnormal mitochondrial remodeling during neural differentiation of human pluripotent stem cells via SIRT3/AMPK pathway inhibition. Cell Cycle. ISSN 1538-4101. 21(11), p. 1178–1193. doi: 10.1080/15384101.2022.2044136. Full text in Research Archive
  • Sharma, Kulbhushan; Asp, Nagham Theres; Harrison, Sean; Siller, Richard; Baumgarten, Saphira Felicitas & Gupta, Swapnil [Show all 10 contributors for this article] (2021). Autophagy modulates cell fate decisions during lineage commitment. Autophagy. ISSN 1554-8627. p. 1–17. doi: 10.1080/15548627.2021.2008691. Full text in Research Archive
  • Mostafavi, Sepideh; Balafkan, Novin; Pettersen, Ina Katrine Nitschke; Nido, Gonzalo Sanchez; Siller, Richard & Tzoulis, Charalampos [Show all 8 contributors for this article] (2021). Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 9, p. 1–12. doi: 10.3389/fcell.2021.744777. Full text in Research Archive
  • Chen, Anbin; Kristiansen, Cecilie Katrin; Hong, Yu; Kianian, Atefeh; Fang, Fei & Sullivan, Gareth John [Show all 10 contributors for this article] (2021). Nicotinamide riboside and metformin ameliorate mitophagy defect in induced pluripotent stem cell-derived astrocytes with POLG mutations. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 9, p. 1–20. doi: 10.3389/fcell.2021.737304. Full text in Research Archive
  • Convery, Neil; Samardzhieva, Iliyana; Stormonth-Darling, John Moir; Harrison, Sean; Sullivan, Gareth John & Gadegaard, Nikolaj (2021). 3D printed tooling for injection moulded microfluidics. Macromolecular materials and engineering (Print). ISSN 1438-7492. 306(11), p. 1–11. doi: 10.1002/mame.202100464. Full text in Research Archive
  • Fernandez-Checa, Jose C; Bagnaninchi, Pierre-Olivier; Ye, H; Sancho-Bru, Pau; Falcon-Perez, JM & Royo, Felix [Show all 21 contributors for this article] (2021). Advanced preclinical models for evaluation of drug induced liver injury - consensus statement by the european drug-induced liver injury network [PRO-EURO-DILI-NET]. . Journal of Hepatology. ISSN 0168-8278. 75(4), p. 935–959. doi: 10.1016/j.jhep.2021.06.021. Full text in Research Archive
  • Harrison, Sean; Baumgarten, Saphira Felicitas; Verma, Rajneesh; Lunov, Oleg; Dejneka, Alexandr & Sullivan, Gareth (2021). Liver Organoids: Recent Developments, Limitations and Potential. Frontiers in medicine. ISSN 2296-858X. 8. doi: 10.3389/fmed.2021.574047. Full text in Research Archive
  • Aprigliano, Rossana; Aksu, Merdane Ezgi; Bradamante, Stefano; Mihaljevic, Boris; Wang, Wei & Rian, Kristin [Show all 19 contributors for this article] (2021). Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities. Cell Reports Medicine. ISSN 2666-3791. 2(4). doi: 10.1016/j.xcrm.2021.100240. Full text in Research Archive
  • Liang, Xiao; Kianian, Atefeh; Chen, Anbin; Kristiansen, Cecilie Katrin; Hong, Yu & Furriol, Jessica [Show all 12 contributors for this article] (2021). Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons. BioRxiv. ISSN 0362-4331. doi: 10.1101/2020.12.20.423652.
  • Skottvoll, Frøydis Sved; Hansen, Frederik; Harrison, Sean; Boger, Ida Caroline Sneis; Mrsa, Ago & Restan, Magnus Saed [Show all 14 contributors for this article] (2021). Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies. Analytical Chemistry. ISSN 0003-2700. 93, p. 3576–3585. doi: 10.1021/acs.analchem.0c05082. Full text in Research Archive
  • Kim, Jonghun; Sullivan, Gareth & Park, In-Hyun (2021). How well do brain organoids capture your brain? iScience. ISSN 2589-0042. 24(2), p. 1–14. doi: 10.1016/j.isci.2021.102063. Full text in Research Archive
  • Harrison, Sean; Siller, Richard; Tanaka, Yoshiaki; Xiang, Yangfei; Patterson, Benjamin & Kempf, Henning [Show all 29 contributors for this article] (2020). Scalable production of tissue-like vascularised liver organoids from human PSCs. BioRxiv. ISSN 0362-4331. doi: 10.1101/2020.12.02.406835.
  • Liang, Xiao; Vatne, Guro Helén; Kristiansen, Cecilie Katrin; Ievglevskyi, Oleksandr; Kondratskaya, Elena & Glover, Joel [Show all 9 contributors for this article] (2020). N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation. Experimental Neurology. ISSN 0014-4886. 337. doi: 10.1016/j.expneurol.2020.113536.
  • Kogler, Stian; Harrison, Sean; Aizenshtadt, Aleksandra; Skottvoll, Frøydis Sved; Abadpour, Shadab & Krauss, Stefan [Show all 10 contributors for this article] (2020). “Organoid-in-a-column” coupled on-line with liquid chromatography-mass spectrometry. BioRxiv. ISSN 0362-4331. doi: 10.1101/2020.09.08.282756.
  • Balafkan, Novin; Mostafavi, Sepideh; Schubert, Manja; Siller, Richard; Liang, Kristina Xiao & Sullivan, Gareth [Show all 7 contributors for this article] (2020). A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96‐well microplates. Scientific Reports. ISSN 2045-2322. 10, p. 1–14. doi: 10.1038/s41598-020-73656-2. Full text in Research Archive
  • Liang, Xiao; Kristiansen, Cecilie Katrin; Mostafavi, Sepideh; Vatne, Guro Helén; Zantingh, Gina Alien & Kianian, Atefeh [Show all 17 contributors for this article] (2020). Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations. EMBO Molecular Medicine. ISSN 1757-4676. 12(10), p. 1–26. doi: 10.15252/emmm.202012146. Full text in Research Archive
  • Xiang, Yangfei; Tanaka, Yoshiaki; Patterson, Benjamin; Hwang, Sun-Min; Hysolli, Eriona & Cakir, Bilal [Show all 17 contributors for this article] (2020). Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons. Molecular Cell. ISSN 1097-2765. 79(1), p. 84–98. doi: 10.1016/j.molcel.2020.05.016. Full text in Research Archive
  • Tanaka, Yoshiaki; Cakir, Bilal; Xiang, Yangfei; Sullivan, Gareth & Park, In-Hyun (2020). Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain. Cell reports. ISSN 2211-1247. 30(6), p. 1682–1689. doi: 10.1016/j.celrep.2020.01.038. Full text in Research Archive
  • Lin, Ann; Skottvoll, Frøydis Sved; Rayner, Simon; Pedersen-Bjergaard, Stig; Sullivan, Gareth & Krauss, Stefan [Show all 8 contributors for this article] (2019). 3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry. Electrophoresis. ISSN 0173-0835. 41, p. 56–64. doi: 10.1002/elps.201900170. Full text in Research Archive
  • Bogdanova, Mariia; Zabirnyk, Arsenii; Malashicheva, Anna; Zihlavnikova, Katarina; Karlsen, Tommy Aleksander & Kaljusto, Mari-Liis [Show all 13 contributors for this article] (2019). Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties. Scientific Reports. ISSN 2045-2322. 9:12934, p. 1–13. doi: 10.1038/s41598-019-49016-0. Full text in Research Archive
  • Bogdanova, Mariia; Kostina, Aleksandra; Zihlavnikova, Katarina; Zabirnyk, Arsenii; Malashicheva, Anna & Stensløkken, Kåre-Olav [Show all 12 contributors for this article] (2018). Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells. Frontiers in Physiology. ISSN 1664-042X. 9. doi: 10.3389/fphys.2018.01635. Full text in Research Archive
  • Kim, Kun-Yong; Tanaka, Yoshiaki; Su, Juan; Cakir, Bilal; Xiang, Yangfei & Patterson, Benjamin [Show all 20 contributors for this article] (2018). Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a. Nature Communications. ISSN 2041-1723. 9:2583, p. 1–13. doi: 10.1038/s41467-018-04818-0. Full text in Research Archive
  • Pisal, Rishikaysh V.; Suchánek, Jakub; Siller, Richard; Soukup, Tomáš; Hrebíková, Hana & Bezrouk, Ales [Show all 11 contributors for this article] (2018). Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth. Scientific Reports. ISSN 2045-2322. 8(1). doi: 10.1038/s41598-018-24421-z. Full text in Research Archive
  • Siller, Richard; Greenhough, Sebastian; Mathapati, Santosh Sadashiv; Si-Tayeb, K & Sullivan, Gareth (2017). Future challenges in the generation of hepatocyte like cells from human pluripotent stem cells. Current Pathobiology Reports. ISSN 2167-485X. 5(3), p. 301–314. doi: 10.1007/s40139-017-0150-x.
  • Scarfe, Lauren; Brillant, Nathalie; Kumar, J. Dinesh; Ali, Noura; Alrumayh, Ahmed & Amali, Mohammed [Show all 39 contributors for this article] (2017). Pre-clinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. Nature partner journals regenerative medicine. ISSN 2057-3995. 2(28). doi: 10.1038/s41536-017-0029-9.
  • Sullivan, Gareth & Siller, Richard (2017). Simple and rapid screen for human pluripotent stem cell endoderm differentiation potential. Current protocols in stem cell biology. ISSN 1941-7322. 43, p. 1G.7.1–1G.7.23. doi: 10.1002/cpsc.36.
  • Rutkovskiy, Arkady; Malashicheva, Anna; Sullivan, Gareth; Bogdanova, Mariia; Kostareva, Anna & Stensløkken, Kåre-Olav [Show all 8 contributors for this article] (2017). Valve interstitial cells: The key to understanding the pathophysiology of heart valve calcification. Journal of the American Heart Association (JAHA). ISSN 2047-9980. 6(9), p. 1–24. doi: 10.1161/JAHA.117.006339.
  • Siller, Richard; Dufour, Eric; Lycke, Eric Maximilian; Wilmut, Ian; Jung, Yong Wook & Park, In-Hyun [Show all 7 contributors for this article] (2017). Development of an inducible platform for intercellular protein delivery. International Journal of Pharmaceutics. ISSN 0378-5173. 522(1-2), p. 1–10. doi: 10.1016/j.ijpharm.2017.02.067.
  • Gamal, Wesam; Treskes, Philipp; Samuel, Kay; Sullivan, Gareth; Siller, Richard & Srsen, Vlastimil [Show all 20 contributors for this article] (2017). Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Scientific Reports. ISSN 2045-2322. 7:37541, p. 1–16. doi: 10.1038/srep37541.
  • XU, m; Stattin, EL; Shaw, G; Heinegård, Dick; Sullivan, Gareth & Wilmut, Ian [Show all 14 contributors for this article] (2016). Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an ER stress response and defective matrix assembly. Stem Cells Translational Medicine. ISSN 2157-6564. 5(9), p. 1171–1181. doi: 10.5966/sctm.2015-0384.
  • Mathapati, Santosh Sadashiv; Siller, Richard; Impellizzeri, Agata Antonina Rita; Lycke, Eric Maximilian; Vegheim, Karianne & Almaas, Runar [Show all 7 contributors for this article] (2016). Small-molecule-directed hepatocyte-like cell differentiation of human pluripotent stem cells. Current protocols in stem cell biology. ISSN 1941-7322. 38, p. 1G.6.1–1G.6.18. doi: 10.1002/cpsc.13.
  • Siller, Richard; Naumovska, Elena; Mathapati, Santosh Sadashiv; Lycke, Max; Greenhough, Sebastian & Sullivan, Gareth (2016). Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep37178. Full text in Research Archive
  • Siller, Richard; Greenhough, Sebastian; Naumovska, Elena & Sullivan, Gareth (2015). Small-molecule-driven hepatocyte differentiation of human pluripotent stem cells. Stem Cell Reports. ISSN 2213-6711. 4(5), p. 939–952. doi: 10.1016/j.stemcr.2015.04.001. Full text in Research Archive
  • Dajani, Rana; Koo, Sung-Eun; Sullivan, Gareth & Park, In-Hyun (2013). Investigation of Rett Syndrome Using Pluripotent Stem Cells. Journal of Cellular Biochemistry. ISSN 0730-2312. 114(11), p. 2446–2453. doi: 10.1002/jcb.24597.
  • Siller, Richard; Greenhough, Sebastian; Park, IH & Sullivan, Gareth (2013). Modelling Human Disease with Pluripotent Stem Cells. Current Gene Therapy. ISSN 1566-5232. 13(2), p. 99–110. doi: 10.2174/1566523211313020004.
  • Kim, Kun-Yong; Jung, Yong Wook; Sullivan, Gareth; Chung, Leeyup & Park, In-Hyun (2012). Cellular reprogramming: a novel tool for investigating autism spectrum disorders. Trends in Molecular Medicine. ISSN 1471-4914. 18(8), p. 463–471. doi: 10.1016/j.molmed.2012.06.002.
  • Zhou, Xiao-Ling; Sullivan, Gareth; Sun, Pingnan & Park, In-Hyung (2012). Humanized Murine Model for HBV and HCV Using Human Induced Pluripotent Stem Cells. Archives of pharmacal research. ISSN 0253-6269. 35(2), p. 261–269. doi: 10.1007/s12272-012-0206-8.

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  • Dugarte, Maria Eugenia Chollet; andersen, elisabeth; de la Morena-Barrio, Maria Eugenia; Bravo-Perez, Carlos; Mowinckel, Marie-Christine & Myklebust, Christiane Fillion [Show all 12 contributors for this article] (2020). Characterizing Coagulation FVII from iPSC-Hepatocytes-like Cells: Setting the Basis for Cell Therapy Development. Blood. ISSN 0006-4971. 136. doi: 10.1182/blood-2020-139211.
  • Skottvoll, Frøydis Sved; Harrison, Sean; Hansen, Frederik; Pedersen-Bjergaard, Stig; Sullivan, Gareth & Bogen, Inger Lise [Show all 8 contributors for this article] (2020). Liver mini-organ analyses using liquid chromatography mass spectrometry.
  • Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean; Sullivan, Gareth & Lundanes, Elsa [Show all 8 contributors for this article] (2020). Determination of liver organoid-induced drug metabolites using liquid chromatography-mass spectrometry (LC-MS)”.
  • Mrša, Ago; Skottvoll, Frøydis Sved; Harrison, Sean; Lundanes, Elsa; Sullivan, Gareth & Wilson, Steven Ray Haakon (2020). Miniaturized liquid chromatography systems for small molecule analysis of organoids.
  • Dugarte, Maria Eugenia Chollet; Andersen, Elisabeth; Skarpen, Ellen; Mowinckel, Marie-Christine; Stavik, Benedicte & Sullivan, Gareth [Show all 7 contributors for this article] (2019). FVII: A human pluripotent stem cell derived hepatocyte model with potential therapeutic applications. Research and Practice in Thrombosis and Haemostasis. ISSN 2475-0379. 3.
  • Mrša, Ago; Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean & Lundanes, Elsa [Show all 9 contributors for this article] (2019). Studying organoid drug metabolism using UHPLC/nanoLC-MS.
  • Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Harrison, Sean; Nerem, Elisabeth; Bogen, Inger Lise & Sullivan, Gareth [Show all 7 contributors for this article] (2019). LC-MS approaches to liver organoid analyses.
  • Skottvoll, Frøydis Sved; Nilsen, Ola; Krauss, Stefan; Sullivan, Gareth & Wilson, Steven Ray Haakon (2018). Integrating highly miniaturized LC-MS systems with “Organ on a Chip”; the future of preclinical modelling .
  • Impellizzeri, Agata Antonina Rita; Szabo, Attila; Fjerdingstad, Hege Brincker; Sullivan, Gareth; Glover, Joel & Andreassen, Ole Andreas [Show all 7 contributors for this article] (2017). Using Stem Cells to Understand the Underlying Mechanisms of Polygenic Risk of Severe Mental Disorders.

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Published Jan. 18, 2012 12:38 PM - Last modified Aug. 8, 2020 9:35 AM