Helga Refsum

Image of Helga Refsum
Norwegian version of this page
Room 2195
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 Oslo
Postal address Postboks 1046 Blindern 0317 Oslo
Other affiliations Division of Molecular Nutrition

Publications

  • Elshorbagy, Amany K.; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga & Kwok, Timothy (2022). The association of serum sulfur amino acids and related metabolites with incident diabetes: a prospective cohort study. European Journal of Nutrition. ISSN 1436-6207. doi: 10.1007/s00394-022-02872-5.
  • Włoczkowska, Olga; Perła-Kaján, Joanna; Smith, A. David; de Jager, Celeste; Refsum, Helga & Jakubowski, Hieronim (2021). Anti-N-homocysteine-protein autoantibodies are associated with impaired cognition. Alzheimer's and Dementia: Translational Research and Clinical Interventions. ISSN 2352-8737. 7(1), p. 1–10. doi: 10.1002/trc2.12159. Full text in Research Archive
  • Perła-Kaján, Joanna; Włoczkowska, Olga; Zioła-Frankowska, Anetta; Frankowski, Marcin; Smith, A. David & de Jager, Celeste [Show all 8 contributors for this article] (2021). Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment. Journal of Alzheimer's Disease. ISSN 1387-2877. 81(3), p. 1211–1229. doi: 10.3233/JAD-210137. Full text in Research Archive
  • Smith, A. David; Jernerén, Fredrik & Refsum, Helga (2021). ω-3 fatty acids and their interactions. American Journal of Clinical Nutrition. ISSN 0002-9165. 113(4), p. 775–778. doi: 10.1093/ajcn/nqab013.
  • Alshahawy, Rasha; Habachi, Nihal El; Allam, Eman; Jernerén, Fredrik; Refsum, Helga & Elshorbagy, Amany K (2021). Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. ISSN 0899-9007. 90. doi: 10.1016/j.nut.2021.111306.
  • Jakubowski, Hieronim; Zioła-Frankowska, Anetta; Frankowski, Marcin; Perła-Kaján, Joanna; Refsum, Helga & De Jager, Celeste A. [Show all 7 contributors for this article] (2021). B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment. Journal of Alzheimer's Disease. ISSN 1387-2877. 84(3), p. 1039–1055. doi: 10.3233/JAD-215085. Full text in Research Archive
  • Smith, A.D. & Refsum, Helga (2021). Homocysteine – from disease biomarker to disease prevention. Journal of Internal Medicine. ISSN 0954-6820. 290(4), p. 826–854. doi: 10.1111/joim.13279.
  • Wu, Y.; Smith, A.D.; Refsum, H. & Kwok, Timothy (2021). Effectiveness of B Vitamins and Their Interactions with Aspirin in Improving Cognitive Functioning in Older People with Mild Cognitive Impairment: Pooled Post-Hoc Analyses of Two Randomized Trials. The Journal of Nutrition, Health & Aging. ISSN 1279-7707. 25, p. 1154–1160. doi: 10.1007/s12603-021-1708-1. Full text in Research Archive
  • Elkafrawy, Hagar; Mehanna, Radwa; Ali, Fayrouz; Barghash, Ayman; Dessouky, Iman & Jernerén, Fredrik [Show all 9 contributors for this article] (2021). Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults. Amino Acids. ISSN 0939-4451. 53, p. 1623–1634. doi: 10.1007/s00726-021-03071-y. Full text in Research Archive
  • Stolt, Emma Theresia Kjelland; Olsen, Thomas; Elshorbagy, Amany; Kozich, Viktor; Van Greevenbroek, Marleen M.J. & Øvrebø, Bente [Show all 10 contributors for this article] (2021). Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements. Journal of Translational Medicine. ISSN 1479-5876. 19. doi: 10.1186/s12967-021-02824-3. Full text in Research Archive
  • Vinknes, Kathrine; Refsum, Helga; Turner, Cheryl; Khaw, Kay-Tee; Wareham, Nicholas J. & Forouhi, Nita G. [Show all 7 contributors for this article] (2021). Plasma Sulfur Amino Acids and Risk of Cerebrovascular Diseases: A Nested Case-Control Study in the EPIC-Norfolk Cohort. Stroke. ISSN 0039-2499. 52(1), p. 172–180. doi: 10.1161/STROKEAHA.120.029177.
  • Olsen, Thomas; Øvrebø, Bente; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga & Vinknes, Kathrine (2021). Effects of short-term methionine and cysteine restriction and enrichment with polyunsaturated fatty acids on oral glucose tolerance, plasma amino acids, fatty acids, lactate and pyruvate: results from a pilot study. BMC Research Notes. ISSN 1756-0500. 14(43). doi: 10.1186/s13104-021-05463-5. Full text in Research Archive
  • Pérez, Laura M.; Hooshmand, Babak; Mangialasche, Francesca; Mecocci, Patrizia; Smith, A David & Refsum, Helga [Show all 10 contributors for this article] (2020). Glutathione Serum Levels and Rate of Multimorbidity Development in Older Adults. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1079-5006. 75(6), p. 1089–1094. doi: 10.1093/gerona/glz101. Full text in Research Archive
  • Elshorbagy, Amany; Graham, Ian & Refsum, Helga (2020). Body mass index determines the response of plasma sulfur amino acids to methionine loading. Biochimie. ISSN 0300-9084. 173, p. 107–113. doi: 10.1016/j.biochi.2020.03.001.
  • Olsen, Thomas; Sollie, Ove; Nurk, Eha; Turner, Cheryl; Jernerén, Fredrik & Ivy, John L. [Show all 10 contributors for this article] (2020). Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists. Frontiers in Physiology. ISSN 1664-042X. doi: 10.3389/fphys.2020.609335. Full text in Research Archive
  • Lee-Ødegård, Sindre; Gulseth, Hanne Løvdal; Langleite, Torgrim Mikal; Norheim, Frode; Olsen, Thomas & Refsum, Helga [Show all 9 contributors for this article] (2020). Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men. Diabetologia. ISSN 0012-186X. 64, p. 410–423. doi: 10.1007/s00125-020-05296-0. Full text in Research Archive
  • Olsen, Thomas; Turner, Cheryl; Øvrebø, Bente; Bastani, Nasser Ezzatkhah; Refsum, Helga & Vinknes, Kathrine (2020). Postprandial effects of a meal low in sulfur amino acids and high in polyunsaturated fatty acids compared to a meal high in sulfur amino acids and saturated fatty acids on stearoyl CoA-desaturase indices and plasma sulfur amino acids: a pilot study. BMC Research Notes. ISSN 1756-0500. 13. doi: 10.1186/s13104-020-05222-y. Full text in Research Archive
  • Olsen, Thomas; Øvrebø, Bente; Haj Yasein, Nadia; Lee-Ødegård, Sindre; Svendsen, Karianne & Hjorth, Marit [Show all 11 contributors for this article] (2020). Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study. Journal of Translational Medicine. ISSN 1479-5876. 18(122). doi: 10.1186/s12967-020-02288-x. Full text in Research Archive
  • Henjum, Sigrun; Manger, Mari Skar; Hampel, Daniela; Brantsæter, Anne Lise; Shahab-Ferdows, Setareh & Bastani, Nasser Ezzatkhah [Show all 9 contributors for this article] (2020). Vitamin B12 concentrations in milk from Norwegian women during the six first months of lactation. European Journal of Clinical Nutrition. ISSN 0954-3007. 74(5), p. 749–756. doi: 10.1038/s41430-020-0567-x.
  • Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A David; Turner, Cheryl & Palmblad, Jan [Show all 13 contributors for this article] (2019). Homocysteine status modifies the treatment effect of omega-3 fatty acids on cognition in a randomized clinical trial in mild to moderate Alzheimer's disease: The OmegAD Study. Journal of Alzheimer's Disease. ISSN 1387-2877. 69(1), p. 189–197. doi: 10.3233/JAD-181148.
  • Hooshmand, Babak; Refsum, Helga; Smith, A David; Kalpouzos, Gregoria; Mangialasche, Francesca & Von Arnim, Christine A.F. [Show all 9 contributors for this article] (2019). Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia. JAMA psychiatry. ISSN 2168-6238. 76(11), p. 1198–1205. doi: 10.1001/jamapsychiatry.2019.1694.
  • Su, Yi; Elshorbagy, Amany; Turner, Cheryl; Refsum, Helga; Chan, Ruth & Kwok, Timothy (2019). Circulating amino acids are associated with bone mineral density decline and ten-year major osteoporotic fracture risk in older community-dwelling adults. Bone. ISSN 8756-3282. 129, p. 1–8. doi: 10.1016/j.bone.2019.115082.
  • Olsen, Thomas; Vinknes, Kathrine; Blomhoff, Rune; Lysne, Vegard; Midttun, Øivind & Dhar, Indu [Show all 12 contributors for this article] (2019). Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease. European Journal of Nutrition. ISSN 1436-6207. doi: 10.1007/s00394-019-02086-2. Full text in Research Archive
  • Hanvold, Susanna; Vinknes, Kathrine; Løken, Elin Bjørge; Hjartåker, Anette; Klungsøyr, Ole & Birkeland, Eline [Show all 10 contributors for this article] (2019). Does Lifestyle Intervention After Gastric Bypass Surgery Prevent Weight Regain? A Randomized Clinical Trial. Obesity Surgery. ISSN 0960-8923. 29(11), p. 3419–3431. doi: 10.1007/s11695-019-04109-7.
  • Lee-Ødegård, Sindre; Olsen, Thomas; Vinknes, Kathrine; Refsum, Helga; Gulseth, Hanne Løvdal & Birkeland, Kåre I. [Show all 7 contributors for this article] (2019). Plasma Sulphur-Containing Amino Acids, Physical Exercise and Insulin Sensitivity in Overweight Dysglycemic and Normal Weight Normoglycemic Men. Nutrients. ISSN 2072-6643. 11(1). doi: 10.3390/nu11010010. Full text in Research Archive
  • Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Tell, Grethe S.; Nygård, Ottar; Mccann, Adrian & Ueland, Per Magne [Show all 13 contributors for this article] (2019). The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study. Brain, Behavior, and Immunity. ISSN 0889-1591. 75, p. 155–162. doi: 10.1016/j.bbi.2018.10.003.
  • Elshorbagy, Amany; Samocha-Bonet, D.; Jernerén, Fredrik; Turner, Cheryl; Refsum, Helga & Heilbronn, Leonie K. (2018). Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain. Journal of Nutrition. ISSN 0022-3166. 148(7), p. 1073–1080. doi: 10.1093/jn/nxy062.
  • Allen, Lindsay H.; Miller, Joshua W.; de Groot, Lisette; Rosenberg, Irwin H.; Smith, A. David & Refsum, Helga [Show all 7 contributors for this article] (2018). Biomarkers of Nutrition for Development (BOND): Vitamin B-12 Review. Journal of Nutrition. ISSN 0022-3166. 148(4), p. 1995S–2027S. doi: 10.1093/jn/nxy201.
  • Sollie, Ove; Jeppesen, Per Bendix; Tangen, Daniel S.; Jernerén, Fredrik; Nellemann, Birgitte & Valsdottir, Thorhildur [Show all 12 contributors for this article] (2018). Protein intake in the early recovery period after exhaustive exercise improves performance the following day. Journal of applied physiology. ISSN 8750-7587. 125(6), p. 1731–1742. doi: 10.1152/japplphysiol.01132.2017. Full text in Research Archive
  • Olsen, Thomas; Øvrebø, Bente; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga & Vinknes, Kathrine (2018). Combining Dietary Sulfur Amino Acid Restriction with Polyunsaturated Fatty Acid Intake in Humans: A Randomized Controlled Pilot Trial. Nutrients. ISSN 2072-6643. 10(12), p. 1–15. doi: 10.3390/nu10121822. Full text in Research Archive
  • Wanders, Anne J.; Alssema, Marjan; De Hoon, Sabine E.M.; Feskens, Edith J.M.; van Woudenbergh, Geertruida J. & Van Der Kallen, Carla J. [Show all 14 contributors for this article] (2018). Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies. Annals of Nutrition and Metabolism. ISSN 0250-6807. 72(2), p. 117–125. doi: 10.1159/000486244.
  • Olsen, Thomas; Vinknes, Kathrine; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Dhar, Indu & Tell, Grethe S. [Show all 11 contributors for this article] (2018). The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A. European Journal of Preventive Cardiology (EJPC). ISSN 2047-4873. 25(15), p. 1612–1620. doi: 10.1177/2047487318788587. Full text in Research Archive
  • Smith, A. David; Refsum, Helga; Bottiglieri, Teodoro; Fenech, Michael; Hooshmand, Babak & McCaddon, Andrew [Show all 9 contributors for this article] (2018). Homocysteine and Dementia: An International Consensus Statement. Journal of Alzheimer's Disease. ISSN 1387-2877. 62(2), p. 561–570. doi: 10.3233/JAD-171042. Full text in Research Archive
  • Elshorbagy, Amany; Jernerén, Fredrik; Basta, Marianne; Basta, Caroline; Turner, Cheryl & Khaled, Maram [Show all 7 contributors for this article] (2017). Amino acid changes during transition to a vegan diet supplemented with fish in healthy humans. European Journal of Nutrition. ISSN 1436-6207. 56(5), p. 1953–1962. doi: 10.1007/s00394-016-1237-6.
  • Vinknes, Kathrine; Nurk, Eha; Tell, Grethe S.; Sulo, Gerhard; Refsum, Helga & Elshorbagy, Amany K. (2017). The relation of CUN-BAE index and BMI with body fat, cardiovascular events and diabetes during a 6-year follow-up: The hordaland health study. Clinical Epidemiology. ISSN 1179-1349. 9, p. 555–566. doi: 10.2147/CLEP.S145130.
  • Holm, Maia Blomhoff; Bastani, Nasser Ezzatkhah; Holme, Ane Moe; Zucknick, Manuela; Jansson, Thomas & Refsum, Helga [Show all 10 contributors for this article] (2017). Uptake and release of amino acids in the fetal-placental unit in human pregnancies. PLOS ONE. ISSN 1932-6203. 12(10). doi: 10.1371/journal.pone.0185760. Full text in Research Archive
  • Hanvold, Susanna; Vinknes, Kathrine; Bastani, Nasser Ezzatkhah; Turner, Cheryl; Løken, Elin Bjørge & Mala, Tom [Show all 8 contributors for this article] (2017). Plasma amino acids, adiposity, and weight change after gastric bypass surgery: are amino acids associated with weight regain? European Journal of Nutrition. ISSN 1436-6207. p. 1–9. doi: 10.1007/s00394-017-1533-9.
  • Melvær, Giil Lasse; Midttun, Øivind; Refsum, Helga; Ulvik, Arve; Advani, Rajiv & Smith, A. David [Show all 7 contributors for this article] (2017). Kynurenine pathway metabolites in Alzheimer's disease. Journal of Alzheimer's Disease. ISSN 1387-2877. 60(2), p. 495–504. doi: 10.3233/JAD-170485.
  • Haj Yasein, Nadia; Berg, Ole; Jerneren, Fredrik; Refsum, Helga; Nebb, Hilde Irene & Dalen, Knut Tomas (2017). Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1862(6), p. 623–635. doi: 10.1016/j.bbalip.2017.02.009.
  • Olsen, Thomas; Vinknes, Kathrine; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Tell, Grethe S. & Blomhoff, Rune [Show all 11 contributors for this article] (2017). Cardiovascular disease risk associated with serum apolipoprotein B is modified by serum vitamin A. Atherosclerosis. ISSN 0021-9150. p. 325–330. doi: 10.1016/j.atherosclerosis.2017.07.020.
  • Kumar, Tivendra; Taneja, Sunita; Sachdev, Harshpal S; Refsum, Helga; Yajnik, Chittaranjan S. & Bhandari, Nita [Show all 7 contributors for this article] (2017). Supplementation of vitamin B12 or folic acid on hemoglobin concentration in children 6-36 months of age: A randomized placebo controlled trial. Clinical Nutrition. ISSN 0261-5614. 36(4), p. 986–991. doi: 10.1016/j.clnu.2016.07.002.
  • Parr, Christine Louise; Magnus, Maria Christine; Karlstad, Øystein; Haugen, Alice Margaretha; Refsum, Helga & Ueland, Per Magne [Show all 11 contributors for this article] (2017). Maternal folate intake during pregnancy and childhood asthma in a population-based cohort. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X. 195(2), p. 221–228. doi: 10.1164/rccm.201604-0788OC.
  • Zhang, Weihua; Jernerén, Fredrik; Lehne, Benjamin C.; Chen, Ming-Huei; Luben, Robert N. & Johnston, Carole [Show all 19 contributors for this article] (2016). Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thrombosis and Haemostasis. ISSN 0340-6245. 116(6), p. 1041–1049. doi: 10.1160/TH16-02-0151.
  • Elshorbagy, Amany K; Jernerén, Fredrik; Scudamore, Cheryl L.; McMurray, Fiona; Cater, Heather & Hough, Tertius [Show all 8 contributors for this article] (2016). Exploring the lean phenotype of glutathione-depleted mice: Thiol, amino acid and fatty acid profiles. PLOS ONE. ISSN 1932-6203. 11(10). doi: 10.1371/journal.pone.0163214.
  • Cabout, Mieke; Alssema, Marjan; Nijpels, Giel; Stehouwer, Coen D.A.; Zock, Peter L. & Brouwer, Ingeborg A. [Show all 8 contributors for this article] (2016). Circulating linoleic acid and alpha-linolenic acid and glucose metabolism: the Hoorn Study. European Journal of Nutrition. ISSN 1436-6207. Published ahead of print. doi: 10.1007/s00394-016-1261-6.
  • Hooshmand, Babak; Mangialasche, Francesca; Kalpouzos, Grégoria; Solomon, Alina; Kåreholt, Ingemar & Smith, A. David [Show all 14 contributors for this article] (2016). Association of Vitamin B<sub>12</sub>, folate, and sulfur amino acids with brain magnetic resonance imaging measures in older adults a longitudinal population-based study. JAMA psychiatry. ISSN 2168-6238. 73(6), p. 606–613. doi: 10.1001/jamapsychiatry.2016.0274.
  • Smith, A. David & Refsum, Helga (2016). Homocysteine, B Vitamins, and Cognitive Impairment. Annual review of nutrition. ISSN 0199-9885. 36, p. 211–239. doi: 10.1146/annurev-nutr-071715-050947.
  • Elshorbagy, Amany K.; Jernerén, Fredrik; Samocha-Bonet, D.; Refsum, Helga & Heilbronn, L.K. (2016). Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans. Nutrition and Diabetes. ISSN 2044-4052. 6. doi: 10.1038/nutd.2015.44.
  • Oulhaj, Abderrahim; Jernerén, Fredrik; Refsum, Helga; Smith, A. David & de Jager, Celeste A. (2015). Omega-3 fatty acid status enhances the prevention of cognitive decline by B Vitamins in mild cognitive impairment. Journal of Alzheimer's Disease. ISSN 1387-2877. 50(2), p. 547–557. doi: 10.3233/JAD-150777.
  • Jernerén, Fredrik; Elshorbagy, Amany K.; Oulhaj, Abderrahim; Smith, Stephen M.; Refsum, Helga & Smith, A. David (2015). Brain atrophy in cognitively impaired elderly: The importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial. American Journal of Clinical Nutrition. ISSN 0002-9165. 102(1), p. 215–221. doi: 10.3945/ajcn.114.103283.
  • Strand, Tor; Taneja, Sunita; Kumar, Tivendra; Manger, Mari Skar; Refsum, Helga & Yajnik, Chittaranjan S. [Show all 7 contributors for this article] (2015). Vitamin B-12, folic acid, and growth in 6- to 30-month-old children: A randomized controlled trial. Pediatrics. ISSN 0031-4005. 135(4), p. e918–e926. doi: 10.1542/peds.2014-1848.
  • Kvestad, Ingrid; Taneja, Sunita; Kumar, Tivendra; Hysing, Mari; Refsum, Helga & Yajnik, Chittaranjan S. [Show all 8 contributors for this article] (2015). Vitamin B12 and folic acid improve gross motor and problem-solving skills in young North Indian children: A randomized placebo-controlled trial. PLOS ONE. ISSN 1932-6203. 10(6). doi: 10.1371/journal.pone.0129915. Full text in Research Archive
  • Hanvold, Susanna; Løken, Elin Bjørge; Paus, Sofie Flottorp; de Brisis, Eva Rustad; Bjerkan, Kirsti & Refsum, Helga [Show all 7 contributors for this article] (2015). Great Health Benefits But No Change in Employment or Psychopharmaceutical Drug Use 2 Years After Roux-en-Y Gastric Bypass. Obesity Surgery. ISSN 0960-8923. 25(9), p. 1672–1679. doi: 10.1007/s11695-015-1583-0.
  • Yajnik, Chittaranjan S; Chandak, Giriraj R; Joglekar, Charudatta V; Katre, Prachi; Bhat, Dattatray S & Singh, Suraj N [Show all 12 contributors for this article] (2014). Maternal homocysteine in pregnancy and offspring birthweight: Epidemiological associations and Mendelian randomization analysis. International Journal of Epidemiology. ISSN 0300-5771. 43(5), p. 1487–1497. doi: 10.1093/ije/dyu132.
  • Ulak, Manjeswori; Chandyo, Ram Krishna; Adhikari, Ramesh K.; Sharma, Pushpa R.; Sommerfelt, Halvor & Refsum, Helga [Show all 7 contributors for this article] (2014). Cobalamin and folate status in 6 to 35 months old children presenting with acute diarrhea in Bhaktapur, Nepal. PLOS ONE. ISSN 1932-6203. 9(3:e90097). doi: 10.1371/journal.pone.0090079. Full text in Research Archive
  • Doets, EL; Ueland, Per Magne; Tell, Grethe S; Vollset, Stein Emil; Nygård, Ottar & van't Veer, Pieter [Show all 11 contributors for this article] (2014). Interactions between plasma concentrations of folate and markers of vitamin B12 status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study. British Journal of Nutrition. ISSN 0007-1145. 111(6), p. 1085–1095. doi: 10.1017/S000711451300336X.
  • Vogiatzoglou, Anna; Smith, David; Nurk, Eha; Drevon, Christian A; Ueland, Per Magne & Vollset, Stein Emil [Show all 10 contributors for this article] (2013). Cognitive function in an elderly population: Interaction between vitamin B12 status, depression and apolipoprotein E4. The Hordaland Homocysteine Study. Psychosomatic Medicine. ISSN 0033-3174. 75(1), p. 20–29. doi: 10.1097/PSY.0b013e3182761b6c.
  • Vinknes, Kathrine; Elshorbagy, Amany K; Nurk, Eha; Drevon, Christian A; Gjesdal, Clara Gram & Tell, Grethe S [Show all 9 contributors for this article] (2013). Plasma stearoyl-CoA desaturase indices: Association with lifestyle, diet and body composition. Obesity. ISSN 1930-7381. 21(3), p. E294–E302. doi: 10.1002/oby.20011.
  • Nurk, Eha; Refsum, Helga; Bjelland, Ingvar; Drevon, Christian A; Tell, Grethe S & Ueland, Per Magne [Show all 10 contributors for this article] (2013). Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. British Journal of Nutrition. ISSN 0007-1145. 109(3), p. 511–519. doi: 10.1017/S0007114512001249. Full text in Research Archive
  • Strand, Bjørn Heine; Langballe, Ellen Melbye; Hjellvik, Vidar; Handal, Marte; Næss, Øyvind & Knudsen, Gun Peggy [Show all 15 contributors for this article] (2013). Midlife vascular risk factors and their association with dementia deaths: Results from a Norwegian prospective study followed up for 35 years. Journal of Neurological Sciences. ISSN 1302-1664. 324(1-2), p. 124–130. doi: 10.1016/j.jns.2012.10.018.
  • Reinders, Ilse; van Ballegooijen, Adriana J.; Visser, Marjolein; Elshorbagy, Amany K.; Refsum, Helga & Henry, Ronald M.A. [Show all 10 contributors for this article] (2013). Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. European Journal of Clinical Nutrition. ISSN 0954-3007. 67(12), p. 1277–1283. doi: 10.1038/ejcn.2013.167.
  • Haj-Yasein, Nadia Nabil; Dalen, Knut Tomas; Berg, Ole; Bastani, Nasser Ezzatkhah; Refsum, Helga & Nebb, Hilde Irene (2013). Low Cysteine Interferes With PPARγ Activity And Reduces Adipocyte Differentiation. The Journal of Inherited Metabolic Disease (JIMD). ISSN 0141-8955. 36. doi: 10.1007/s10545-013-9631-1.
  • Reinders, I; Ballegooijen, A J van; Visser, M; Elshorbagy, AK; Refsum, Helga & Henry, R.M.A. [Show all 10 contributors for this article] (2013). Low Cysteine Interferes With PPARγ Activity And Reduces Adipocyte Differentiation. European Journal of Clinical Nutrition. ISSN 0954-3007. doi: 10.1038/ejcn.2013.167.
  • Elshorbagy, AK; Nijpels, G; Valdivia-Garcia, Maria; Stehouwer, C.D.A.; Ocké, Marga C & Refsum, Helga [Show all 7 contributors for this article] (2013). S-Adenosylmethionine Is Associated with Fat Mass and Trunkal Adiposity in Older Adults. Journal of Nutrition. ISSN 0022-3166. 143(12), p. 1982–1988. doi: 10.3945/jn.113.179192.
  • Vinknes, Kathrine; Elshorbagy, Amany K.; Drevon, Christian A; Nurk, Eha; Tell, Grethe S & Nygård, Ottar [Show all 8 contributors for this article] (2013). Associations between plasma polyunsaturated fatty acids, plasma stearoyl-CoA desaturase indices and body fat. Obesity. ISSN 1930-7381. 21(9), p. E512–E519. doi: 10.1002/oby.20457.
  • Vinknes, Kathrine; Dekker, Jacqueline M.; Drevon, Christian A; Refsum, Helga; Nurk, Eha & Nijpels, Giel [Show all 13 contributors for this article] (2013). Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two caucasian populations. Prostaglandins Leukot Essent Fatty Acids 2. Prostaglandins, Leukotrienes and Essential Fatty Acids. ISSN 0952-3278. 89(5), p. 297–303. doi: 10.1016/j.plefa.2013.09.007.
  • Taneja, Sunita; Strand, Tor A; Kumar, Tivendra; Mahesh, Madhu; Mohan, Sanjana & Manger, Mari Skar [Show all 9 contributors for this article] (2013). Folic acid and vitamin B-12 supplementation and common infections in 6-30-mo-old children in India: a randomized placebo-controlled trial. American Journal of Clinical Nutrition. ISSN 0002-9165. 98(3), p. 731–737. doi: 10.3945/ajcn.113.059592.
  • Douaud, Gwenaëlle; Refsum, Helga; de Jager, Celeste; Jacoby, Robin; Nichols, Thomas E & Smith, Stephen M. [Show all 7 contributors for this article] (2013). Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 110(23), p. 9523–9528. doi: 10.1073/pnas.1301816110.
  • Elshorbagy, Amany K.; Valdivia-Garcia, Maria; Mattocks, Dwight A.L.; Plummer, Jason D.; Orentreich, David S. & Orentreich, Norman [Show all 8 contributors for this article] (2013). Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance. Metabolism: Clinical and Experimental. ISSN 0026-0495. 62(4), p. 509–517. doi: 10.1016/j.metabol.2012.10.005.
  • Rajagopalan, Priya; Refsum, Helga; Hua, Xue; Toga, Arthur W.; Jack, Clifford R. & Weiner, Michael W [Show all 7 contributors for this article] (2013). Mapping creatinine- and cystatin C-related white matter brain deficits in the elderly. Neurobiology of Aging. ISSN 0197-4580. 34(4), p. 1221–1230. doi: 10.1016/j.neurobiolaging.2012.10.022.
  • Vinknes, Kathrine; Elshorbagy, Amany K.; Drevon, Christian A; Gjesdal, Clara Gram; Tell, Grethe S & Nygård, Ottar [Show all 8 contributors for this article] (2013). Evaluation of the body adiposity index in a caucasian population: the Hordaland Health Study. American Journal of Epidemiology. ISSN 0002-9262. 177(6), p. 586–592. doi: 10.1093/aje/kws271.
  • Strand, Tor A; Taneja, Sunita; Ueland, Per Magne; Refsum, Helga; Bahl, Rajiv & Schneede, Jørn [Show all 8 contributors for this article] (2013). Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age. American Journal of Clinical Nutrition. ISSN 0002-9165. 97(2), p. 310–317. doi: 10.3945/ajcn.111.032268.
  • Elshorbagy, AK; Valdivia-Garcia, Maria; Graham, I. M.; Reis, R Palma; Luis, A Sales & Smith, A.D. [Show all 7 contributors for this article] (2012). The association of fasting plasma sulfur-containing compounds with BMI, serum lipids and apolipoproteins. NMCD. Nutrition Metabolism and Cardiovascular Diseases. ISSN 0939-4753. 22(12), p. 1031–1038. doi: 10.1016/j.numecd.2011.01.008.
  • Elshorbagy, Amany K; Valdivia-Garcia, Maria; Refsum, Helga & Butte, Nancy (2012). The Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents. PLOS ONE. ISSN 1932-6203. 7(9). doi: 10.1371/journal.pone.0044166. Full text in Research Archive
  • de Jager, Celeste; Oulhaj, Abderrahim; Jacoby, Robin; Refsum, Helga & Smith, A. David (2012). Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial. International Journal of Geriatric Psychiatry. ISSN 0885-6230. 27(6), p. 592–600. doi: 10.1002/gps.2758.
  • Elshorbagy, Amany K.; Church, Chris; Valdivia-Garcia, Maria; Smith, A. David; Refsum, Helga & Cox, Roger (2012). Dietary cystine level affects metabolic rate and glycaemic control in adult mice. Journal of Nutritional Biochemistry. ISSN 0955-2863. 23(4), p. 332–340. doi: 10.1016/j.jnutbio.2010.12.009.
  • Elshorbagy, Amany K; Smith, A. David; Kozich, Viktor & Refsum, Helga (2012). Cysteine and Obesity. Obesity. ISSN 1930-7381. 20(3), p. 473–481. doi: 10.1038/oby.2011.93.
  • Elshorbagy, Amany K; Kozich, Viktor; Smith, A. David & Refsum, Helga (2012). Cysteine and obesity: consistency of the evidence across epidemiologic, animal and cellular studies. Current opinion in clinical nutrition and metabolic care. ISSN 1363-1950. 15(1), p. 49–57. doi: 10.1097/MCO.0b013e32834d199f.
  • Bonilla, Carolina; Lawlor, Debbie A.; Taylor, Amy E; Gunnell, David; Ben-Shlomo, Yoav & Ness, Andrew R [Show all 16 contributors for this article] (2012). Vitamin B-12 Status during Pregnancy and Child's IQ at Age 8: A Mendelian Randomization Study in the Avon Longitudinal Study of Parents and Children. PLOS ONE. ISSN 1932-6203. 7(12). doi: 10.1371/journal.pone.0051084.
  • Aasheim, Erlend T; Elshorbagy, Amany K; Diep, Lien My; Søvik, Torgeir Thorson; Mala, Tom & Valdivia-Garcia, Maria [Show all 10 contributors for this article] (2011). Effect of bariatric surgery on sulphur amino acids and glutamate. British Journal of Nutrition. ISSN 0007-1145. 106(3), p. 432–440. doi: 10.1017/S0007114511000201. Full text in Research Archive
  • Lehmann, Donald J; Refsum, Helga; Warden, Donald R; Medway, Christopher; Wilcock, Gordon K & Smith, David (2011). The vitamin D receptor gene is associated with Alzheimer's disease. Neuroscience Letters. ISSN 0304-3940. 504(2), p. 79–82. doi: 10.1016/j.neulet.2011.08.057.
  • Manger, Mari Skar; Taneja, Sunita; Strand, Tor A; Ueland, Per Magne; Refsum, Helga & Schneede, Jørn [Show all 9 contributors for this article] (2011). Poor folate status predicts persistent diarrhea in 6- to 30-month-old north Indian children. Journal of Nutrition. ISSN 0022-3166. 141(12), p. 2226–2232. doi: 10.3945/jn.111.144220.
  • Bleie, Øyvind; Strand, Elin; Ueland, Per Magne; Vollset, Stein Emil; Refsum, Helga & Igland, Jannicke [Show all 8 contributors for this article] (2011). Coronary blood flow in patients with stable coronary artery disease treated long term with folic acid and vitamin B12. Coronary Artery Disease. ISSN 0954-6928. 22(4), p. 270–278. doi: 10.1097/MCA.0b013e328344fff4.
  • Manger, Mari Skar; Strand, Tor A; Taneja, Sunita; Refsum, Helga; Ueland, Per Magne & Nygård, Ottar [Show all 9 contributors for this article] (2011). Cobalamin Status Modifies the Effect of Zinc Supplementation on the Incidence of Prolonged Diarrhea in 6-to 30-Month-Old North Indian Children. Journal of Nutrition. ISSN 0022-3166. 141(6), p. 1108–1113. doi: 10.3945/jn.110.127415.
  • Hay, Gry; Trygg, Kerstin Ulla; Whitelaw, Andrew; Johnston, Carole & Refsum, Helga (2011). Folate and cobalamin status in relation to diet in healthy 2-y-old children. American Journal of Clinical Nutrition. ISSN 0002-9165. 93(4), p. 727–735. doi: 10.3945/ajcn.110.003426.
  • Elshorbagy, Amany K; Valdivia-Garcia, Maria; Mattocks, Dwight A.L.; Plummer, Jason D.; Smith, A. David & Drevon, Christian A [Show all 8 contributors for this article] (2011). Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase. Journal of Lipid Research. ISSN 0022-2275. 52(1), p. 104–112. doi: 10.1194/jlr.M010215.
  • Vinknes, Kathrine; De Vogel, Stefan; Elshorbagy, Amany K; Nurk, Eha; Drevon, Christian A & Gjesdal, Clara Gram [Show all 9 contributors for this article] (2011). Dietary intake of protein is positively associated with percent body fat in middle-aged and older adults. Journal of Nutrition. ISSN 0022-3166. 141(3), p. 440–446. doi: 10.3945/jn.110.133710.
  • Collin, Simon M.; Metcalfe, Chris; Refsum, Helga; Lewis, Sarah; Smith, George Davey & Cox, Angela [Show all 15 contributors for this article] (2010). Associations of Folate, Vitamin B-12, Homocysteine, and Folate-Pathway Polymorphisms with Prostate-Specific Antigen Velocity in Men with Localized Prostate Cancer. Cancer Epidemiology, Biomarkers and Prevention. ISSN 1055-9965. 19(11), p. 2833–2838. doi: 10.1158/1055-9965.EPI-10-0582.
  • Oulhaj, Abderrahim; Refsum, Helga; Beaumont, Helen; Williams, Jonathan; King, Elizabeth & Jacoby, Robin [Show all 7 contributors for this article] (2010). Homocysteine as a predictor of cognitive decline in Alzheimer's disease. International Journal of Geriatric Psychiatry. ISSN 0885-6230. 25(1), p. 82–90.
  • de Lau, LML; van Meurs, JBJ; Uitterlinden, André G.; Smith, AD; Refsum, Helga & Johnston, C [Show all 7 contributors for this article] (2010). Genetic variation in homocysteine metabolism, cognition, and white matter lesions. Neurobiology of Aging. ISSN 0197-4580. 31(11), p. 2020–2022. doi: 10.1016/j.neurobiolaging.2008.10.004.

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  • Skålhegg, Bjørn Steen & Refsum, Helga (2012). Mat og Medisin. Kapittel 11, B-vitaminer. Cappelen Damm Akademisk. ISBN 978-82-7634-967-2. 18 p.

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  • Smith, A. David; Refsum, Helga & Miller, Joshua W. (2019). Dietary Supplements for Brain Health. Journal of the American Medical Association (JAMA). ISSN 0098-7484. 321(24). doi: 10.1001/jama.2019.4963.
  • Refsum, Helga & Smith, A. David (2017). To the editor. JAMA pediatrics. ISSN 2168-6203. 171(7), p. 710–711. doi: 10.1001/jamapediatrics.2017.0866.
  • Smith, A. David; Refsum, Helga; Selhub, Jacob & Rosenberg, Irwin H. (2016). Decision on folic acid fortification in Europe must consider both risks and benefits. The BMJ. ISSN 1756-1833. 352:i734, p. 1–2. doi: 10.1136/bmj.i734.
  • Smith, A. David; Refsum, Helga & Jacoby, Robin (2016). Evidence-based prevention and treatment of dementia. Lancet Neurology. ISSN 1474-4422. 15(10), p. 1005–1006. doi: 10.1016/S1474-4422%2816%2930074-6.
  • Smith, David A; de Jager, Celeste A.; Refsum, Helga & Rosenberg, Irwin H. (2015). Homocysteine lowering, B vitamins, and cognitive aging. American Journal of Clinical Nutrition. ISSN 0002-9165. 101(2), p. 415–416. doi: 10.3945/ajcn.114.098467.
  • Strand, Tor; Taneja, Sunita; Kumar, Tivendra; Manger, Mari Skar; Refsum, Helga & Yajnik, Chittaranjan S [Show all 7 contributors for this article] (2014). The Effect of Daily Vitamin B12 and Folic Acid Supplementation on Growth in 6-30 Month Old Children in India: A Randomized Controlled Trial.
  • Dalen, Knut Tomas; Haj-Yasein, Nadia Nabil; Berg, Ole; Refsum, Helga & Nebb, Hilde Irene (2014). Cysteine and adipocyte differentiation.
  • Smith, A. David & Refsum, Helga (2012). Do we need to reconsider the desirable blood level of vitamin B12? Journal of Internal Medicine. ISSN 0954-6820. 271(2), p. 179–182. doi: 10.1111/j.1365-2796.2011.02485.x.
  • Clarke, Robert; Halsey, J; Lewington, S; Lonn, E; Armitage, J. & Manson, JE [Show all 24 contributors for this article] (2010). Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.

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Published Apr. 13, 2011 2:40 PM - Last modified Jan. 29, 2014 12:34 PM