Academic interests
- Brain volume regulation and osmosensing
- Physiopathological roles of aquaporins in the brain
- Novel mechanisms of disease and therapeutical targets in the neurodegenerative disorders
- Role of the brain extracellular matrix in health and disease
Other interests
Courses taught
Background
- M.D. from the University of Oslo (UiO) 1996
- PhD in 2003 (UiO)
- Postdoc at the Department of Developmental Biology, Harvard Medical School in 2006
- Group leader at the Laboratory for Molecular Neuroscience (LMN) since 2009-
Other
- Research director at the Section for biology and medicine, OxySolutions AS, November 2010- 2015
Awards
Positions held
Collaboration
- Peter Agre (Nobel Laureate in 2003): Johns Hopkins School of Public Health
- Bjorn R. Olsen, Department of Developmental Biology, Harvard School of Dental Medicine
- John Rash, State University of Colorado
- Stefano Ferroni, Department of Human and General Physiology, University of Bologna
- Roberto Zamboni, Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), Bologna
Tags:
Brain and Nervous System,
Cell volume regulation,
Aquaporins,
Astrocytes,
Human Rights,
Neurological disorders
Publications
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Vatnehol, Svein Are Sirirud; Hol, Per Kristian; Bjørnerud, Atle; Amiry-Moghaddam, Mahmood; Haglerød, Camilla & Storås, Tryggve
(2020).
Effect of drinking oxygenated water assessed by in vivo MRI relaxometry.
Journal of Magnetic Resonance Imaging.
ISSN 1053-1807.
52(3),
p. 720–728.
doi:
10.1002/jmri.27104.
Full text in Research Archive
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Katoozi, Shirin; Skauli, Nadia; Rahmani, Soulmaz; Deshpande, Tushar; Ezan, Pascal & Palazzo, Claudia
[Show all 11 contributors for this article]
(2020).
Uncoupling of the Astrocyte Syncytium Differentially Affects AQP4 Isoforms.
Cells.
ISSN 2073-4409.
doi:
10.3390/cells9020382.
Full text in Research Archive
Show summary
The water channel protein aquaporin-4 (AQP4) and the gap junction forming proteins connexin-43 (Cx43) and connexin-30 (Cx30) are astrocytic proteins critically involved in brain water and ion homeostasis. While AQP4 is mainly involved in water flux across the astrocytic endfeet membranes, astrocytic gap junctions provide syncytial coupling allowing intercellular exchange of water, ions, and other molecules. We have previously shown that mice with targeted deletion of Aqp4 display enhanced gap junctional coupling between astrocytes. Here, we investigate whether uncoupling of the astrocytic syncytium by deletion of the astrocytic connexins Cx43 and Cx30 affects AQP4 membrane localization and expression. By using quantitative immunogold cytochemistry, we show that deletion of astrocytic connexins leads to a substantial reduction of perivascular AQP4, concomitant with a down-regulation of total AQP4 protein and mRNA. Isoform expression analysis shows that while the level of the predominant AQP4 M23 isoform is reduced in Cx43/Cx30 double deficient hippocampal astrocytes, the levels of M1, and the alternative translation AQP4ex isoform protein levels are increased. These findings reveal a complex interdependence between AQP4 and connexins, which are both significantly involved in homeostatic functions and astrogliopathologies.
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Katoozi, Shirin; Shreyas, Rao; Skauli, Nadia; Froehner, Stanley C.; Ottersen, Ole Petter & Adams, Marv
[Show all 7 contributors for this article]
(2020).
Functional specialization of retinal Müller cell endfeet depends on an interplay between two syntrophin isoforms.
Molecular Brain.
ISSN 1756-6606.
13.
doi:
10.1186/s13041-020-00581-w.
Full text in Research Archive
Show summary
Retinal Müller cells are highly polarized macroglial cells with accumulation of the aquaporin-4 (AQP4) water channel and the inwardly rectifying potassium channel Kir4.1 at specialized endfoot membrane domains abutting microvessels and corpus vitreum. Proper water and potassium homeostasis in retina depends on these membrane specializations. Here we show that targeted deletion of β1-syntrophin leads to a partial loss of AQP4 from perivascular Müller cell endfeet and that a concomitant deletion of both α1- and β1-syntrophin causes a near complete loss of AQP4 from both perivascular and subvitreal endfoot membranes. α1-syntrophin is normally very weakly expressed in Müller cell endfeet but β1-syntrophin knockout mice display an increased amount of α1-syntrophin at these sites. We suggest that upregulation of perivascular α1-syntrophin restricts the effect of β1-syntrophin deletion. The present findings indicate that β1-syntrophin plays an important role in maintaining the functional polarity of Müller cells and that α1-syntrophin can partially substitute for β1-syntrophin in AQP4 anchoring. Functional polarization of Müller cells thus depends on an interplay between two syntrophin isoforms.
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Prydz, Agnete; Stahl, Katja; Rahmani, Soulmaz; Skauli, Nadia; Skare, Øivind & Ottersen, Ole Petter
[Show all 7 contributors for this article]
(2020).
Pro-inflammatory role of AQP4 in mice subjected to intrastriatal injections of the Parkinsonogenic toxin MPP.
Cells.
ISSN 2073-4409.
9:2418(11).
doi:
10.3390/cells9112418.
Full text in Research Archive
Show summary
Aquaporin-4 (AQP4) is critically involved in brain water and volume homeostasis and has been implicated in a wide range of pathological conditions. Notably, evidence has been accrued to suggest that AQP4 plays a proinflammatory role by promoting release of astrocytic cytokines that activate microglia and other astrocytes. Neuroinflammation is a hallmark of Parkinson's disease (PD), and we have previously shown that astrocytes in substantia nigra (SN) are enriched in AQP4 relative to cortical astrocytes, and that their complement of AQP4 is further increased following treatment with the parkinsonogenic toxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Here, we investigated the effect of Aqp4 deletion on microglial activation in mice subjected to unilateral intrastriatal injection of 1-methyl-4-phenylpyridinium (MPP+, the toxic metabolite of MPTP). Our results show that MPP+ injections lead to a pronounced increase in the expression level of microglial activating genes in the ventral mesencephalon of wild type (WT) mice, but not Aqp4-/- mice. We also show, in WT mice, that MPP+ injections cause an upregulation of nigral AQP4 and swelling of astrocytic endfeet. These findings are consistent with the idea that AQP4 plays a pro-inflammatory role in Parkinson's disease, secondary to the dysregulation of astrocytic volume homeostasis.
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Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna & Mylonakou, Maria-Niki
[Show all 13 contributors for this article]
(2018).
Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease.
PLOS ONE.
ISSN 1932-6203.
13(3).
doi:
10.1371/journal.pone.0194896.
Full text in Research Archive
Show summary
More than 90% of the cases of Parkinson’s disease have unknown etiology. Gradual loss of dopaminergic neurons of substantia nigra is the main cause of morbidity in this disease. External factors such as environmental toxins are believed to play a role in the cell loss, although the cause of the selective vulnerability of dopaminergic neurons remains unknown. We have previously shown that aquaglyceroporin AQP9 is expressed in dopaminergic neurons and astrocytes of rodent brain. AQP9 is permeable to a broad spectrum of substrates including purines, pyrimidines, and lactate, in addition to water and glycerol. Here we test our hypothesis that AQP9 serves as an influx route for exogenous toxins and, hence, may contribute to the selective vulnerability of nigral dopaminergic (tyrosine hydroxylase-positive) neurons. Using Xenopus oocytes injected with Aqp9 cRNA, we show that AQP9 is permeable to the parkinsonogenic toxin 1-methyl-4-phenylpyridinium (MPP+). Stable expression of AQP9 in HEK cells increases their vulnerability to MPP+ and to arsenite—another parkinsonogenic toxin. Conversely, targeted deletion of Aqp9 in mice protects nigral dopaminergic neurons against MPP+ toxicity. A protective effect of Aqp9 deletion was demonstrated in organotypic slice cultures of mouse midbrain exposed to MPP+ in vitro and in mice subjected to intrastriatal injections of MPP+ in vivo. Seven days after intrastriatal MPP+ injections, the population of tyrosine hydroxylase-positive cells in substantia nigra is reduced by 48% in Aqp9 knockout mice compared with 67% in WT littermates. Our results show that AQP9 –selectively expressed in catecholaminergic neurons—is permeable to MPP+ and suggest that this aquaglyceroporin contributes to the selective vulnerability of nigral dopaminergic neurons by providing an entry route for parkinsonogenic toxins. To our knowledge this is the first evidence implicating a toxin permeable membrane channel in the pathophysiology of Parkinson’s disease.
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Nakayama, Shin; Migliati, Elton; Amiry-Moghaddam, Mahmood; Ottersen, Ole Petter & Bhardwaj, Anish
(2016).
Osmotherapy with hypertonic saline attenuates global cerebral edema following experimental cardiac arrest via perivascular pool of aquaporin-4.
Critical Care Medicine.
ISSN 0090-3493.
44(8),
p. e702–e710.
doi:
10.1097/CCM.0000000000001671.
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Nakayama, Shin; Amiry-Moghaddam, Mahmood; Ottersen, Ole Petter & Bhardwaj, Anish
(2016).
Conivaptan, a Selective Arginine Vasopressin V<sub>1a</sub> and V<sub>2</sub> Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4.
Neurocritical Care.
ISSN 1541-6933.
24(2),
p. 273–282.
doi:
10.1007/s12028-015-0236-4.
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Camassa, Laura Maria Azzurra; Lunde, Lisa Kristina; Hoddevik, Eystein Hellstrøm; Stensland, Maria; Boldt, Henning Bunsow & De Souza, Gustavo Antonio
[Show all 8 contributors for this article]
(2015).
Mechanisms underlying AQP4 accumulation in astrocyte endfeet.
Glia.
ISSN 0894-1491.
63(11),
p. 2073–2091.
doi:
10.1002/glia.22878.
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Ricanek, Petr; Lunde, Lisa Kristina; Frye, Stephan Alfons; Støen, Mari; Nygård, Ståle & Morth, Jens Preben
[Show all 10 contributors for this article]
(2015).
Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease.
Clinical and Experimental Gastroenterology.
ISSN 1178-7023.
8,
p. 49–67.
doi:
10.2147/CEG.S70119.
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Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood ; Bergersen, Linda Hildegard; Bjaalie, Jan G.; Eriksson, Jens & Gundersen, Vidar
[Show all 12 contributors for this article]
(2013).
The glia doctrine: Addressing the role of glial cells in healthy brain ageing.
Mechanisms of Ageing and Development.
ISSN 0047-6374.
134(10),
p. 449–459.
doi:
10.1016/j.mad.2013.10.001.
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Amiry-Moghaddam, Mahmood & Ottersen, Ole Petter
(2013).
Immunogold cytochemistry in neuroscience.
Nature Neuroscience.
ISSN 1097-6256.
16(7),
p. 798–804.
doi:
10.1038/nn.3418.
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Promeneur, Dominique; Lunde, Lisa Kristina; Amiry-Moghaddam, Mahmood & Agre, Peter
(2013).
Protective role of brain water channel AQP4 in murine cerebral malaria.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
110(3),
p. 1035–1040.
doi:
10.1073/pnas.1220566110.
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Kielland, Anders; Camassa, Laura Maria Azzurra; Døhlen, Gaute; Munthe, Ludvig Andre; Blomhoff, Rune & Amiry-Moghaddam, Mahmood
[Show all 7 contributors for this article]
(2012).
NF-kappa B Activity in Perinatal Brain During Infectious and Hypoxic-Ischemic Insults Revealed by a Reporter Mouse.
Brain Pathology.
ISSN 1015-6305.
22(4),
p. 499–510.
doi:
10.1111/j.1750-3639.2011.00548.x.
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Kielland, Anders; Camassa, Laura Maria Azzurra; Døhlen, Gaute; Munthe, Ludvig Andre; Blomhoff, Rune & Amiry-Moghaddam, Mahmood
[Show all 7 contributors for this article]
(2012).
Activity in Perinatal Brain During Infectious and Hypoxic-Ischemic Insults revealed by a Reporter Mouse.
Brain Pathology.
ISSN 1015-6305.
22(4),
p. 499–510.
doi:
10.1111/j.1750-3639.2011.00548.x.
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Benfenati, Valentina; Caprini, Marco; Dovizio, Melania; Mylonakou, Maria-Niki; Ferroni, Stefano & Ottersen, Ole Petter
[Show all 7 contributors for this article]
(2011).
An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
108(6),
p. 2563–2568.
doi:
10.1073/pnas.1012867108.
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Stahl, Katja; Mylonakou, Maria-Niki; Skare, Øivind; Amiry-Moghaddam, Mahmood & Torp, Reidun
(2011).
Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease.
Brain Research.
ISSN 0006-8993.
1378,
p. 105–118.
doi:
10.1016/j.brainres.2010.12.090.
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Berle, Magnus Foldal; Wester, Knut; Ulvik, Rune Johan; Haaland, Øystein Ariansen; Kroksveen, Ann Cathrine & Amiry-Moghaddam, Mahmood
[Show all 8 contributors for this article]
(2010).
Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults.
Cerebrospinal Fluid Research.
ISSN 1743-8454.
7(1).
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Migliati, Elton R.; Amiry-Moghaddam, Mahmood ; Froehner, S.C.; Adams, Marvin E.; Ottersen, Ole Petter & Bhardwaj, Anish
(2010).
Na+-K+-2Cl(-) Cotransport Inhibitor Attenuates Cerebral Edema Following Experimental Stroke via the Perivascular Pool of Aquaporin-4.
Neurocritical Care.
ISSN 1541-6933.
13(1),
p. 123–131.
doi:
10.1007/s12028-010-9376-8.
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Liu, Xiaoqin; Nakayama, Shin; Amiry-Moghaddam, Mahmood Reza; Ottersen, Ole Petter & Bhardwaj, Anish
(2010).
Arginine-Vasopressin V-1 but not V-2 Receptor Antagonism Modulates Infarct Volume, Brain Water Content, and Aquaporin-4 Expression Following Experimental Stroke.
Neurocritical Care.
ISSN 1541-6933.
12(1),
p. 124–131.
doi:
10.1007/s12028-009-9277-x.
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Jacobsen, Øyvind; Klaveness, Jo; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood Reza & Rongved, Pål
(2009).
Synthesis of cyclic peptide analogues of the 3(10) helical Pro138-Gly144 segment of human aquaporin-4 by olefin metathesis.
Organic and biomolecular chemistry.
ISSN 1477-0520.
7(8),
p. 1599–1611.
doi:
10.1039/b823559g.
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Liu, Xiaoqin; Nakayama, Shin; Amiry-Moghaddam, Mahmood Reza; Ottersen, Ole Petter & Bhardwaj, A
(2009).
Arginine-Vasopressin V(1) but not V (2) Receptor Antagonism Modulates Infarct Volume, Brain Water Content, and Aquaporin-4 Expression Following Experimental Stroke.
Neurocritical Care.
ISSN 1541-6933.
doi:
10.1007/s12028-009-9277-x.
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Liu, Xiaoqin; Zhang, Wenri; Alkayed, Nabil; Froehner, Stanley C.; Adams, Marvin E. & Amiry-Moghaddam, Mahmood Reza
[Show all 9 contributors for this article]
(2008).
Lack of sex-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke.
Journal of Cerebral Blood Flow and Metabolism.
ISSN 0271-678X.
28(12),
p. 1898–1906.
doi:
10.1038/jcbfm.2008.83.
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Benfenati, Valentina; Amiry-Moghaddam, Mahmood Reza; Caprini, Melania; Mylonakou, Maria-Niki; Rapisarda, C & Ottersen, Ole Petter
[Show all 7 contributors for this article]
(2007).
Expression and functional characterization of transient receptor potential vanilloid-related channel 4 (TRPV4) in rat cortical astrocytes.
Neuroscience.
ISSN 0306-4522.
148(4),
p. 876–892.
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Bragg, AD; Amiry-Moghaddam, Mahmood ; Ottersen, Ole Petter & Froehner, S.C.
(2006).
Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin.
Glia.
ISSN 0894-1491.
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Mathisen, Thomas Misje; Nagelhus, Erlend Arnulf; Juoleh, Bahareh; Torp, Reidun; Frydenlund, Didrik Søli & Mylonakou, Maria-Niki
[Show all 18 contributors for this article]
(2006).
Postembedding Immunogold Cytochemistry of Membrane Molecules and Amino Acid Transmitters in the Central Nervous System.
In Záborszky, L.; Wouterlood, F. & Lanciego, J.L. (Ed.),
Neuroanatomical Tract Tracing: Molecules, Neurons, & Systems.
Springer Science+Business Media B.V..
ISSN 0-387-28941-0.
p. 72–108.
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Puwarawuttipanit, W; Bragg, AD; Frydenlund, Didrik Søli; Mylonakou, Maria-Niki; Nagelhus, Erlend Arnulf & Peters, MF
[Show all 12 contributors for this article]
(2006).
Differential effect of alpha-syntrophin knockout on aquaporin-4 and Kir4.1 expression in retinal macroglial cells in mice.
Neuroscience.
ISSN 0306-4522.
137,
p. 165–175.
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Bragg, AD; Amiry-Moghaddam, Mahmood Reza; Ottersen, Ole Petter; Adams, ME & Froehner, SC
(2006).
Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin.
Glia.
ISSN 0894-1491.
53.
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Frydenlund, Didrik Søli; Bhardwaj, A; Otsuka, T; Mylonakou, Maria-Niki; Yasumura, T & Davidson, KGV
[Show all 14 contributors for this article]
(2006).
Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
103,
p. 13532–13536.
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Eid, T; Lee, TSW; Thomas, Marion J.; Amiry-Moghaddam, Mahmood Reza; Bjørnsen, Lars Petter B. W. & Spencer, DD
[Show all 9 contributors for this article]
(2005).
Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
102,
p. 1193–1198.
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Solbu, Tom Tallak; Boulland, Jean-Luc; Zahid, W; Bredahl, May Kristin Lyamouri; Amiry-Moghaddam, Mahmood Reza & Storm-Mathisen, Jon
[Show all 8 contributors for this article]
(2005).
Induction and targeting of the glutamine transporter SN1 to the basolateral membranes of cortical kidney tubule cells during chronic metabolic acidosis suggest a role in pH regulation.
Journal of the American Society of Nephrology.
ISSN 1046-6673.
16.
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Amiry-Moghaddam, Mahmood Reza; Lindland, Heidi; Zelenin, S; Roberg, Bjørg Åse; Gundersen, BB & Petersen, Petur Henry
[Show all 9 contributors for this article]
(2005).
Brain mitochondria contain aquaporin water channels: evidence for the expression of a short AQP9 isoform in the inner mitochondrial membrane.
The FASEB Journal.
ISSN 0892-6638.
19,
p. 1459–1467.
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Amiry-Moghadam, Mahmood Reza; Xue, R; Haug, Finn-Mogens Smejda; Neely, J.D.; Bhardwaj, A & Agre, P
[Show all 10 contributors for this article]
(2004).
Alpha syntrophin deletion removes the perivascular but not the endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia.
The FASEB Journal.
ISSN 0892-6638.
18(3),
p. 542–544.
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Amiry-Moghadam, Mahmood Reza; Frydenlund, Didrik Søli & Ottersen, Ole Petter
(2004).
Anchoring of aquaporin-4 in brain: Molecular mechanisms and implications forthe physiology and pathophysiology of water transport.
Neuroscience.
ISSN 0306-4522.
129(4),
p. 997–1008.
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Amiry-Moghadam, Mahmood Reza; Otsuka, T; Hurn, PD; Traystman, RJ; Haug, Finn-Mogens Smejda & Froehner, SC
[Show all 11 contributors for this article]
(2003).
An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
100(4),
p. 2106–2111.
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Amiry-Moghadam, Mahmood Reza & Ottersen, Ole Petter
(2003).
The molecular basis for water transport in brain.
Nature Reviews Neuroscience.
ISSN 1471-003X.
4(12),
p. 991–1001.
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Amiry-Moghadam, Mahmood Reza; Williamson, A; Palomba, M; Eid, Tore; Lanerolle, NC de & Adams, ME
[Show all 10 contributors for this article]
(2003).
Delayed K+ clearance and intensified seizures associated with Aquaporin-4 mislocalization: Phenotypic defects in brains of alpha-syntrophin-null mice.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
100(23),
p. 13615–13620.
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Neely, J.D.; Amiry-Moghaddam, Mahmood ; Ottersen, Ole Petter; Froehner, SC; Agre, P. & Adams, ME
(2001).
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424.
98(24),
p. 14108–14113.
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Niermann, H.; Amiry-Moghaddam, Mahmood ; Holthoff, K.; Witte, O.W. & Ottersen, Ole Petter
(2001).
A novel role of vasopressin in the brain: modulation of activity-dependent water flux in the neocortex.
Journal of Neuroscience.
ISSN 0270-6474.
21(9),
p. 3045–3051.
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Elkjaer, M; Vajda, Z.; Nejsum, L.N.; Kwon, T.; Jensen, U.B. & Amiry-Moghaddam, Mahmood Reza
[Show all 7 contributors for this article]
(2000).
Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain.
Biochemical and Biophysical Research Communications - BBRC.
ISSN 0006-291X.
p. 1118–1128.
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Wen, H. Z.; Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood ; Agre, P.; Ottersen, Ole Petter & Nielsen, S.P.
(1999).
Ontogeny of water transport in rat brain: postnatal expression of the aquaporin-4 water channel.
European Journal of Neuroscience.
ISSN 0953-816X.
11,
p. 935–945.
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Nielsen, Søren; Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood ; Bourque, C.; Agre, P. & Ottersen, Ole Petter
(1997).
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain.
Journal of Neuroscience.
ISSN 0270-6474.
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Landsend, Alf S.; Amiry-Moghaddam, Mahmood ; Matsubara, Atsushi; Bergersen, Linda Hildegard; Usami, Shin-ichi & Wenthold, R.J.
[Show all 7 contributors for this article]
(1997).
Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses.
Journal of Neuroscience.
ISSN 0270-6474.
-
Nielsen, S.P.; Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood ; Bourque, C.; Agre, P. & Ottersen, Ole Petter
(1997).
Specialized membrane domains for water transport in glial cells: High-resolution immunogold cytochemistry of Aquaporin-4 in rat brain.
Journal of Neuroscience.
ISSN 0270-6474.
17,
p. 171–180.
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Landsend, A. S.; Amiry-Moghaddam, Mahmood ; Matsubara, Atsushi; Bergersen, Linda Hildegard; Usami, Shin-ichi & Wenthold, R.J.
[Show all 7 contributors for this article]
(1997).
Differential localization of _d glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses.
Journal of Neuroscience.
ISSN 0270-6474.
17,
p. 834–842.
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Amiry-Moghaddam, Mahmood Reza; Nagelhus, Erlend Arnulf; Agre, P.; Nielsen, S.P. & Ottersen, Ole Petter
(1996).
Taurine and water channels are colocalized in renal tubule cells and other tissues,
Taurine 2.
Plenum Press.
p. 165–171.
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Amiry-Moghaddam, Mahmood Reza; Nagelhus, Erlend Arnulf & Ottersen, Ole Petter
(1994).
Light- and electronmicroscopic distribution of taurine, an organic osmolyte, in rat renal tubule cells.
Kidney International.
ISSN 0085-2538.
p. 10–22.
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Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood Reza; Lehmann, A. & Ottersen, Ole Petter
(1994).
Taurine as an organic osmolyte in the intact brain: immunocytochemical and biochemical studies.
Advances in Experimental Medicine and Biology.
ISSN 0065-2598.
p. 325–334.
View all works in Cristin
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Olsen, Bjørn Reino; Amiry-Moghaddam, Mahmood & Ottersen, Ole Petter
(2015).
Translational Medical Research.
In Laake, Petter; Benestad, Haakon Breien & Olsen, Bjørn Reino (Ed.),
Research in Medical and Biological Sciences: From Planning and Preparation ot Grant Application and Publication..
Academic Press.
ISSN 978-0-12-799943-2.
p. 213–235.
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Witoszek, Nina & Amiry-Moghaddam, Mahmood
(2014).
"Hijab, galgen og revolusjon".
Dagbladet.
ISSN 0805-3766.
-
Amiry-Moghaddam, Mahmood
(2010).
Aquaporin water channels in health and disease.
The FEBS Journal.
ISSN 1742-464X.
277,
p. 5–5.
-
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Amiry-Moghaddam, Mahmood Reza
(2009).
PHYSIOLOGICAL AND PATHOLOGICAL ROLES OF AQUAPORIN-4 IN THE BRAIN.
Journal of Neurochemistry.
ISSN 0022-3042.
110,
p. 13–13.
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Amiry-Moghaddam, Mahmood
(2009).
Aquaporin-4 water channels as new molecular targets in treatment of brain edema and stroke.
Journal of the Neurological Sciences.
ISSN 0022-510X.
285,
p. S27–S27.
-
Liu, X; Zhang, WR; Alkayed, NJ; Hurn, PD; Froehner, SC & Marvin, AE
[Show all 9 contributors for this article]
(2008).
Lack of gender-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke.
Stroke.
ISSN 0039-2499.
39,
p. 672–673.
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Apr. 13, 2011 2:41 PM
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