Maja Elstad

Image of Maja Elstad
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Phone +47 22851221
Room 2369
Username
Visiting address Domus Medica Gaustad Sognsvannveien 9 0372 Oslo
Postal address Postboks 1103,Blindern 0317 Oslo

Academic interests

  • Cardiovascular physiology
  • Cardiovascular oscillations
  • Cardiovascular reflexes
  • Stroke volume measurement
  • Cerebral blood flow
  • Skin circulation

Courses taught

  • Leader second year Medical School (MED2200)
  • Medicine basic education, physiology courses

Background

  • 2015-present: Associate Professor
  • 2014-present: Researcher, Young research talent funding from The Research Council of Norway and Institute of Basic Medical Sciences
  • 2011-2014: Postdoc, University of Oslo
  • 2010: Postdoc, University of Bristol
  • 2005-2009: PhD fellowhip, Nasjonalforeningen for folkehelsen at University of Oslo
  • 2004-2005: Turnuslege
  • 2004: MD, University of Oslo
  • 1998-2003: Student research fellow, University of Oslo
  • 1995-97: Mathematical studies, University of Oslo

Honoraria

  • Carl Ludwig award 2012
  • Acta Physiologica and Scandinavian Physiological Society for “an outstanding paper by a young scientist”)
  • Burgen Scholarship 2012
  • Academia Europeae for “early stage scholars at the post-doctoral level”

 

Tags: Blood pressure oscillations, Heart vascular and lungs, Cardiovascular reflexes, Cardiovascular control, Blood pressure

Publications

  • Skytioti, Maria & Elstad, Maja (2022). Respiratory Sinus Arrhythmia is Mainly Driven by Central Feedforward Mechanisms in Healthy Humans. Frontiers in Physiology. ISSN 1664-042X. 13. doi: 10.3389/fphys.2022.768465.
  • Noreen, Shumaila; Ben-Tal, Alona; Elstad, Maja; Sweatman, Winston L.; Ramchandra, Rohit & Paton, Julian (2022). Mathematical modelling of atrial and ventricular pressure–volume dynamics and their change with heart rate. Mathematical Biosciences. ISSN 0025-5564. 344. doi: 10.1016/j.mbs.2021.108766.
  • Lin, Aihua; Kousis, Ilias; Ugland, Nora; Andersen, Marian Berge; Bergersen, Tone Kristin & Stankovski, Tomislav [Show all 8 contributors for this article] (2020). Cardiorespiratory interactions during three different temperatures - a case report. 2020 11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO). doi: 10.1109/ESGCO49734.2020.9158146.
  • Skytioti, Maria; Elstad, Maja & Søvik, Signe (2019). Internal Carotid Artery Blood Flow Response to Anesthesia, Pneumoperitoneum, and Head-up Tilt during Laparoscopic Cholecystectomy. Anesthesiology. ISSN 0003-3022. 131, p. 512–520. doi: 10.1097/ALN.0000000000002838. Full text in Research Archive
  • Elstad, Maja; O'Callaghan, Erin L.; Smith, Alex J.; Ben-Tal, Alona & Ramchandra, Rohit (2018). Cardiorespiratory interactions in humans and animals: rhythms for life. American Journal of Physiology. Heart and Circulatory Physiology. ISSN 0363-6135. 315(1), p. H6–H17. doi: 10.1152/ajpheart.00701.2017. Full text in Research Archive
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2018). Dynamic cerebral autoregulation is preserved during isometric handgrip and head-down tilt in healthy volunteers. Physiological Reports. ISSN 2051-817X. 6(6). doi: 10.14814/phy2.13656. Full text in Research Archive
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2018). Respiratory pump maintains cardiac stroke volume during hypovolemia in young, healthy volunteers. Journal of applied physiology. ISSN 8750-7587. 124(5), p. 1319–1325. doi: 10.1152/japplphysiol.01009.2017. Full text in Research Archive
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2017). Respiration-related cerebral blood flow variability increases during control-mode non-invasive ventilation in normovolemia and hypovolemia. European Journal of Applied Physiology. ISSN 1439-6319. 117(11), p. 2237–2249. doi: 10.1007/s00421-017-3711-0. Full text in Research Archive
  • Elstad, Maja; Zilakos, Ilias & Bergersen, Tone Kristin (2017). Oscillatory pattern of acral skin blood flow within thermoneutral zone in healthy humans. Physiological Measurement. ISSN 0967-3334. 38(5), p. 848–859. doi: 10.1088/1361-6579/aa5fee. Full text in Research Archive
  • Bergersen, Tone Kristin; Skytioti, Maria & Elstad, Maja (2017). Cold-induced sympathetic tone modifies the impact of endothelium-dependent vasodilation in the finger pulp. Autonomic Neuroscience: Basic & Clinical. ISSN 1566-0702. 203, p. 97–102. doi: 10.1016/j.autneu.2016.11.004.
  • Quintana, Daniel; Elstad, Maja; Kaufmann, Tobias; Brandt, Christine Lycke; Haatveit, Beathe Christin & Haram, Marit [Show all 9 contributors for this article] (2016). Resting-state heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls. Scientific Reports. ISSN 2045-2322. 6:37212, p. 1–8. doi: 10.1038/srep37212. Full text in Research Archive
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2016). Internal carotid artery blood flow in healthy awake subjects is reduced by simulated hypovolemia and noninvasive mechanical ventilation. Physiological Reports. ISSN 2051-817X. 4(19). doi: 10.14814/phy2.12969.
  • Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). Heart rate response to therapeutic hypothermia in infants with hypoxic–ischaemic encephalopathy. Resuscitation. ISSN 0300-9572. 106, p. 53–57. doi: 10.1016/j.resuscitation.2016.06.023.
  • Wood, Thomas Ragnar; Smit, Elisa; Maes, Elke; Osredkar, Damjan; Falck, Mari & Elstad, Maja [Show all 7 contributors for this article] (2016). Monitoring of cerebral blood flow during hypoxia-ischemia and resuscitation in the neonatal rat using laser speckle imaging. Physiological Reports. ISSN 2051-817X. 4(7), p. 1–14. doi: 10.14814/phy2.12749. Full text in Research Archive
  • Elstad, Maja & Walløe, Lars (2015). Heart rate variability and stroke volume variability to detect central hypovolemia during spontaneous breathing and supported ventilation in young, healthy volunteers. Physiological Measurement. ISSN 0967-3334. 36(4), p. 671–681. doi: 10.1088/0967-3334/36/4/671.
  • Elstad, Maja; Vanggaard, Leif; Lossius, Astrid Haaskjold; Walløe, Lars & Bergersen, Tone Kristin (2014). Responses in acral and non-acral skin vasomotion and temperature during lowering of ambient temperature. Journal of Thermal Biology. ISSN 0306-4565. 45, p. 168–174. doi: 10.1016/j.jtherbio.2014.09.003.
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2014). Respiratory sinus arrhythmia stabilizes mean arterial blood pressure at high-frequency interval in healthy humans. European Journal of Applied Physiology. ISSN 1439-6319. 115(3), p. 521–530. doi: 10.1007/s00421-014-3042-3.
  • Hannah, Gill; Thoresen, Marianne; Smit, Elisa; Davis, Jonathan; Liu, Xun & Dingley, John [Show all 7 contributors for this article] (2014). Sedation management during therapeutic hypothermia for neonatal encephalopathy: Atropine premedication for endotracheal intubation causes a prolonged increase in heart rate. Resuscitation. ISSN 0300-9572. 85(10), p. 1394–1398. doi: 10.1016/j.resuscitation.2014.07.002.
  • Bergersen, Tone Kristin; Hoffmann-Vold, Anna-Maria; Midtvedt, Øyvind; Gran, Jan Tore; Mørk, Cato & Toska, Karin [Show all 7 contributors for this article] (2014). Dysfunctional arteriovenous anastomoses in hands of systemic sclerosis patients with digital ulcers. Clinical and Experimental Rheumatology. ISSN 0392-856X. 32(6 Suppl 86), p. 53–59.
  • Skranes, Janne Helen; Elstad, Maja; Thoresen, Marianne; Cowan, Frances; Stiris, Tom & Fugelseth, Drude (2014). Hypothermia Makes Cerebral Resistance Index a Poor Prognostic Tool in Encephalopathic Newborns. Neonatology. ISSN 1661-7800. 106(1), p. 17–23. doi: 10.1159/000358229.
  • Dingley, John; Tooley, James; Liu, Xun; Scull-Brown, Emma; Elstad, Maja & Chakkarapani, Elavazhagan [Show all 8 contributors for this article] (2014). Xenon Ventilation During Therapeutic Hypothermia in Neonatal Encephalopathy: A Feasibility Study. Pediatrics. ISSN 0031-4005. 133(5), p. 809–818. doi: 10.1542/peds.2013-0787.
  • Osredkar, Damjan; Thoresen, Marianne; Maes, Elke; Flatebø, Torun; Elstad, Maja & Sabir, Hemmen (2014). Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury. Resuscitation. ISSN 0300-9572. 85(4), p. 567–572. doi: 10.1016/j.resuscitation.2013.12.006.
  • Liu, X; Dingley, John; Elstad, Maja; Brown, EL; Steen, Petter Andreas & Thoresen, Marianne (2013). Minimum Alveolar Concentration (MAC) for Sevoflurane and Xenon at Normothermia and Hypothermia in newborn pigs. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. doi: 10.1111/aas.12055.
  • Elstad, Maja (2012). Respiratory variations in pulmonary and systemic blood flow in healthy humans. Acta Physiologica. ISSN 1748-1708. 205(3), p. 341–348. doi: 10.1111/j.1748-1716.2012.02419.x.
  • Dalen, Marit Lunde; Liu, Xun; Elstad, Maja; Løberg, Else Marit; Saugstad, Ola Didrik & Rootwelt, Terje [Show all 7 contributors for this article] (2012). Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat. Pediatric Research. ISSN 0031-3998. 71(3), p. 247–252. doi: 10.1038/pr.2011.43.
  • Elstad, Maja; Whitelaw, Andrew & Thoresen, Marianne (2011). Cerebral Resistance Index is less predictive in hypothermic encephalopathic newborns. Acta Paediatrica. ISSN 0803-5253. 100(10), p. 1344–1349. doi: 10.1111/j.1651-2227.2011.02327.x.
  • Elstad, Maja; Walløe, Lars; Chon, Ki H. & Toska, Karin (2011). Low-frequency fluctuations in heart rate, cardiac output and mean arterial pressure in humans: what are the physiological relationships? Journal of Hypertension. ISSN 0263-6352. 29(7), p. 1327–1336. doi: 10.1097/HJH.0b013e328347a17a.
  • Elstad, Maja; Nådland, Inger Helene; Toska, Karin & Walløe, Lars (2009). Stroke volume decreases during mild dynamic and static exercise in supine humans. Acta Physiologica. ISSN 1748-1708. 195(2), p. 289–300. doi: 10.1111/j.1748-1716.2008.01887.x.
  • Elstad, Maja; Toska, Karin & Walløe, Lars (2002). Model simulations of cardiovascular changes at the onset of moderate exercise in humans. Journal of Physiology. ISSN 0022-3751. 543(2), p. 719–728.
  • Elstad, Maja; Toska, Karin; Chon, Ki H.; Raeder, Ernst A. & Cohen, Richard J. (2001). Respiratory sinus arrhythmia: opposite effects on systolic and mean arterial pressure in supine humans. Journal of Physiology. ISSN 0022-3751. 536(1), p. 251–259.

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  • Porta, Alberto & Elstad, Maja (2020). Editorial: Probing the Cardiac Arm of the Baroreflex and Complementary Branches. Frontiers in Neuroscience. ISSN 1662-4548. 13. doi: 10.3389/fnins.2019.01422.
  • Holme, Nathalie Linn Anikken; Skytioti, Maria; Søvik, Signe & Elstad, Maja (2020). Induced respiratory variability in arterial blood pressure lowers cerebral blood flow in healthy humans.
  • Noreen, Shumaila; Ben-Tal, Alona; Elstad, Maja; Sweatman, Winston; Ramchandra, Rohit & Paton, Julian (2019). Mathematical Modelling of the Cardiovascular System to Study the Effects of Respiratory Sinus Arrhythmia on Cardiac Output .
  • Skytioti, Maria; Elstad, Maja & Søvik, Signe (2019). Blodflow i arteria carotis interna faller parallelt med cardiac index under laparoskopisk cholecystectomi, uavhengig av blodtrykket.
  • Elstad, Maja (2019). Cardiorespiratory interactions promote human cardiovascular control.
  • Elstad, Maja; Skytioti, Maria; Holme, Nathalie Linn Anikken; Zilakos, Ilias & Lin, Aihua (2019). Cardiorespiratory interactions promote the human cardiovascular control.
  • Ugland, Nora; Lin, Aihua; Bergersen, Tone Kristin; Andersen, Marian Berge; Holme, Nathalie Linn Anikken & Zilakos, Ilias [Show all 7 contributors for this article] (2019). The hemodynamic effects of skin blood flow in human thermoneutral zone.
  • Elstad, Maja; Holme, Nathalie Linn Anikken & Skytioti, Maria (2019). Respiratory sinus arrhythmia and its contribution from the central feedforward command, the arterial baroreflex and the pulmonary stretch reflex in healthy humans.
  • Holme, Nathalie Linn Anikken; Lehre, Martin Andreas; Søvik, Signe; Skytioti, Maria & Elstad, Maja (2019). Cerebral Autoregulation Fails to Maintain Cerebral Blood Flow During Arterial Blood Pressure Oscillations at Respiratory Frequency.
  • Elstad, Maja; Skytioti, Maria; Holme, Nathalie Linn Anikken & Reitan, Harald (2018). Pustepumpen. [Radio]. NRK P2 Ekko.
  • Elstad, Maja; Holme, Nathalie Linn Anikken & Skytioti, Maria (2018). The role of the arterial baroreflex in respiratory sinus arrhythmia in healthy humans.
  • Holme, Nathalie Linn Anikken; Lehre, Martin Andreas; Søvik, Signe; Elstad, Maja & Skytioti, Maria (2018). Responses in cardiac stroke volume index and cardiac index do not differ between genders during moderate central hypovolemia.
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2018). Differential response of internal carotid artery blood flow to cardiac output changes.
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2017). Den respiratoriske sirkulasjonspumpen opprettholder hjertets slagvolum ved hypovolemi hos friske individer.
  • Elstad, Maja (2017). Hva får din indre klokke til å tikke? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(22). doi: 10.4045/tidsskr.17.0901.
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2017). Internal carotid artery blood flow response to isometric handgrip and head down tilt in healthy volunteers.
  • Elstad, Maja (2017). Cardiorespiratory interactions are responsible for both mechanical and nervous cardiovascular oscillations.
  • Elstad, Maja (2017). Cardiorespiratory interactions in humans.
  • Smit, Elisa; Wood, Thomas Ragnar; Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). The effect of resuscitation in 100% Oxygen on cerebral blood flow and neuropathology in a newborn rat model of hypoxia-ischaemia.
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2016). Respiratory sinus arrhythmia buffers variability in cerebral blood flow.
  • Elstad, Maja; Zilakos, Ilias & Bergersen, Tone Kristin (2016). Oscillatory pattern of arteriovenous anastomoses and skin blood flow within thermoneutral zone.
  • Elstad, Maja (2016). Respiratory sinus arrhythmia as buffer of systemic blood flow oscillations.
  • Elstad, Maja (2015). Ujevn hjerterytme stabiliserer blodflyten. [Internet]. http://unikard.org/respiratorisk-sinusarytmi-stabiliserer-bl.
  • Elstad, Maja (2015). Kan avsløre skjult blodtap på vei til sykehus. [Internet]. http://unikard.org/kan-avslore-skjult-blodtap-pa-vei-til-syk.
  • Bergersen, Tone Kristin; Skytioti, Maria & Elstad, Maja (2015). Sympathetic tonus modifies endothelial dependent vasodilation in finger pulp of healthy subjects.
  • Skytioti, Maria; Søvik, Signe & Elstad, Maja (2015). CEREBRAL BLOOD FLOW CHANGES IN RESPONSE TO MILD HYPOVOLEMIA AND POSITIVE PRESSURE VENTILATION.
  • Elstad, Maja (2015). Disse svingningene kan gi oss bedre helse. Aftenposten Viten. ISSN 2464-3033.
  • Osredkar, Damjan; Thoresen, Marianne; Maes, Elke; Flatebo, Torun; Elstad, Maja & Sabir, Hemmen (2014). Hypothermia Is Not Neuroprotective after Infection-Sensitized Neonatal Hypoxic-Ischemic Brain Injury.
  • Gill, Hannah; Thoresen, Marianne; Smit, Elisa; Davis, Jonathan; Liu, Xun & Dingley, John [Show all 7 contributors for this article] (2014). Is Atropine Before Intubation of Term Neonates Justified? An Observation from the CoolXe2 Trial.
  • Elstad, Maja (2014). The respiratory pump improves cardiac stroke volume during central hypovolemia in healthy subjects.
  • Holme, Nathalie; Rein, Erling Bekkestad; Walløe, Lars & Elstad, Maja (2014). Cardiothoracic impedance does not reflect beat-to-beat changes in cardiac stroke volume during mild lower body negative pressure.
  • Elstad, Maja & Walløe, Lars (2014). Left cardiac stroke volume variations during spontaneous breathing and central hypovolemia in healthy subjects.
  • Elstad, Maja (2013). Sats på grunnforskning –ellers vet vi ikke hva vi går glipp av. Aftenposten Viten. ISSN 2464-3033.
  • Elstad, Maja (2013). Forplantning er grunnlaget for nytt liv. In Nicolaysen, Gunnar & Holck, Per (Ed.), Kroppens funksjon og oppbygning. Gyldendal Akademisk. ISSN 9788205323629. p. 257–282.
  • Holme, Nathalie; Rein, Erling Bekkestad; Walloe, Lars; Thoresen, Marianne & Elstad, Maja (2013). Cardiac stroke volume predicts progressive central hypovolemia by three different non-invasive methods. The FASEB Journal. ISSN 0892-6638. 27.
  • Elstad, Maja (2013). Når bølgene i blodet møtes. Forskning.no. ISSN 1891-635X.
  • Skranes, Janne Helen; Thoresen, Marianne; Stiris, Tom; Cowan, Frances; Server, Andres Alonso & Fugelseth, Drude [Show all 7 contributors for this article] (2013). Changes in Cerebral Resistance Index (RI) after rewarming from day three of cooling predicts good but not poor outcome in infants undergoing therapeutic hypothermia.
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2013). Respiratory sinus arrhythmia stabilises mean arterial blood pressure.
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2013). Respiratory sinus arrhythmia stabilises mean arterial blood pressure in healthy humans.
  • Holme, Nathalie; Rein, Erling Bekkestad; Walløe, Lars; Thoresen, Marianne & Elstad, Maja (2013). Cardiac stroke volume predicts progressive central hypovolemia by three different non-invasive methods.
  • Elstad, Maja & Walløe, Lars (2012). Respiratory variations in pulmonary and systemic blood flow in healthy humans.
  • Liu, Xun; Suleiman, M.Saadeh M.; Elstad, Maja; Potter, Helen & Thoresen, Marianne (2010). Effect of Hypothermia on Cardiac Troponin I after Global Hypoxica-ischemia with Brain Injury in Newborn Pigs.
  • Dingley, John; Liu, Xun; Tooley, James; Chakkarapani, Ela; Elstad, Maja & Thoresen, Marianne (2010). First human use of 50% Xenon inhalation during cooling therapy for neonatal hypoxic-ischaemic encephalopathy (HIE): The "CoolXenon" clinical feasibility study.
  • Elstad, Maja; Whitelaw, Andrew & Thoresen, Marianne (2010). Cerebral Doppler Resistance Index in Hypoxic-Ischaemic Encephalopathy: Is it still valid in the cooling era?
  • Opdahl, Anders; Remme, Espen W.; Helle-Valle, Thomas; Vartdal, Trond; Pettersen, Eirik & Elstad, Maja [Show all 9 contributors for this article] (2007). Load-dependency of early-diastolic mitral annulus velocity: the role of systolic function.
  • Opdahl, Anders; Remme, Espen W.; Helle-Valle, Thomas; Vartdal, Trond; Pettersen, Eirik & Elstad, Maja [Show all 9 contributors for this article] (2007). Early Diastolic Mitral Annulus Lengthening Velocity Reflects Coupling between Systolic and Diastolic Function.
  • Elstad, Maja & Toska, Karin (2006). Point: Counterpoint: Cardiovascular variability is/is not an index of autonomic control of circulation. Journal of applied physiology. ISSN 8750-7587. 101, p. 687–687.
  • Opdahl, Anders; Remme, Espen W.; Helle-Valle, Thomas; Vartdal, Trond; Pettersen, Eirik & Elstad, Maja [Show all 9 contributors for this article] (2006). Mitral Annulus Velocity at Onset of Filling - a New Marker of Diastolic Suction.
  • Opdahl, Anders; Remme, Espen W.; Helle-Valle, Thomas; Vartdal, Trond; Pettersen, Eirik & Elstad, Maja [Show all 8 contributors for this article] (2006). Early diastolic mitral annulus velocity at onset of filling a new marker for cardiac suction.
  • Wilhelmsen, Cathrine Monrad & Elstad, Maja (2000). Krise i medisinsk forskning. Aftenposten (morgenutg. : trykt utg.). ISSN 0804-3116.
  • Skytioti, Maria & Elstad, Maja (2019). Regulation of cerebral blood flow and systemic cardiovascular control. Universitet i Oslo Det medisinske fakultet. ISSN 9788283773828.
  • Elstad, Maja (2009). Stroke volume variations : mild exercise and cardiovascular variability. Universitetet i Oslo. ISSN 978-82-8072-378-9.

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Published Apr. 13, 2011 2:41 PM - Last modified Aug. 14, 2015 2:57 PM