Mauricio Moreira Soares
I've obtained a PhD degree on Computational Physics at the University of Coimbra (Portugal) where I worked on the development of mathematical models for biological systems. My work was focused on the description of tumour related phenomena, such as the growth of new blood vessels and cellular migration under spatial confinement. The study of cell migration motivated me to build a software to quantify cell trajectories by applying machine learning to a large set of features. After that I developed further this framework and applied it to experimental data for the study of mitochondrial motility. The interest on biostatistics and machine learning only grew since then, which brought me to my current position as a postdoctoral fellow working on predictive models for head and neck carcinoma.
- 2015-2020 Ph.D in Physics, University of Coimbra - UC, Portugal.
- 2013-2015 Master in Science, Federal University of Pelotas - UFPel, Brazil.
- 2010-2012 Bachelor in Physics, University of Coimbra - UC, Portugal.
- 2009-2013 Bachelor in Physics, Federal University of Pelotas - UFPel, Brazil.
Adhesion modulates cell morphology and migration within dense fibrous networks. M. Moreira-Soares, S. P. Cunha, J. R. Bordin, R. D. M. Travasso. 2020 J. Phys.: Condens. Matter 32 314001, pre-print: https://doi.org/10.1101/838995
Angiogenic Factors produced by Hypoxic Cells are a leading driver of Anastomoses in Sprouting Angiogenesis – a computational study, M. Moreira-Soares, R. Coimbra, L. Rebelo, J. Carvalho, R.D. M Travasso. Scientific Reports 8, 8726 (2018).
Quantitative Analysis of Neuronal Mitochondrial Movement Reveals Patterns Resulting from Neurotoxicity of Rotenone and 6-Hydroxydopamine R. F. Simões, R. Pinho, M. Moreira-Soares, J. Kovarova, J. Neuzil, R. D. M. Travasso, P. J. Oliveira, T. Cunha-Oliveira, F. B. Pereira. (2021)
Thesis & Dissertation
Multi-Phase-Field Models for Biological Systems: From cells to vessels. M. Moreira-Soares (2020). Doctoral Thesis. University of Coimbra.
Coupling blood flow and growing vasculatures in three dimensions. (Portuguese only) M. Moreira-Soares. (2015). Master Dissertation. Universidade Federal de Pelotas.
Simões, Rui F.; Pino, Rute; Moreira Soares, Mauricio; Kovarova, Jaromira; Neuzil, Jiri & Travasso, Rui [Show all 9 contributors for this article] (2021). Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine. The FASEB Journal. ISSN 0892-6638. 35(12). doi: 10.1096/fj.202100899R.