Sandip Kanse

Image of Sandip Kanse
Norwegian version of this page
Phone +47 22851464
Room 1256
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 Oslo
Postal address Postboks 1112 Blindern 0317 Oslo

Academic Interests

  • Proteases in vascular biology
  • Atherosclerosis/stroke/myocardial Infarction
  • Thrombosis/haemostasis
  • Inflammation

Courses taught

  • Medical Biochemistry

Background

  • Habilitation, University of Giessen, Germany, 2003
  • PhD, University of London, UK, 1986-1991
  • BSc Biochemistry, University of London, UK 1983-1986

Previous positions held

  • Member of the Excellence Cluster in Cardiopulmonary Sciences (ECCPS), University of Giessen, Germany (2007-2014)
  • Member of the Sonderforschungsbereich SFB-547 University of Giessen, Germany (2006-2009)
  • Faculty Member, University of Giessen, Germany, 1999-2011
  • Postdoctoral Fellow, Max Planck Institute, Bad Nauheim, Germany, 1994-1998
  • Postdoctoral Fellow, Thrombosis Research Institute, London, UK 1992-1993
Tags: Cardiovascular diseases, stroke, thrombosis, atherosclerosis, coagulation, fibrinolysis. proteases, blood and immunology, inflammation

Publications

1.         Subramaniam S, Kanse SM, Kothari H, Reinhardt C and Fletcher C. Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood coagulation & fibrinolysis. 2018;29:668-682.

2.         Praetner M, Zuchtriegel G, Holzer M, Uhl B, Schaubacher J, Mittmann L, Fabritius M, Furst R, Zahler S, Funken D, Lerchenberger M, Khandoga A, Kanse S, Lauber K, Krombach F and Reichel CA. Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia-Reperfusion. Arteriosclerosis, thrombosis, and vascular biology. 2018;38:829-842.

3.         Olsson M, Stanne TM, Pedersen A, Lorentzen E, Kara E, Martinez-Palacian A, Ronnow Sand NP, Jacobsen AF, Sandset PM, Sidelmann JJ, Engstrom G, Melander O, Kanse SM and Jern C. Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity. Journal of thrombosis and haemostasis. 2018;16:2024-2034.

4.         Grasso S, Neumann A, Lang IM, Etscheid M, von Kockritz-Blickwede M and Kanse SM. Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs). Thrombosis research. 2018;161:36-42.

5.         Etscheid M, Subramaniam S, Lochnit G, Zabczyk M, Undas A, Lang IM, Hanschmann KM and Kanse SM. Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP). Biochim Biophys Acta Mol Basis Dis. 2018;1864:3397-3406.

6.         Cole JW, Xu H, Ryan K, Jaworek T, Dueker N, McArdle P, Gaynor B, Cheng YC, O'Connell J, Bevan S, Malik R, Ahmed NU, Amouyel P, Anjum S, Bis JC, Crosslin D, Danesh J, Engelter ST, Fornage M, Frossard P, Gieger C, Giese AK, Grond-Ginsbach C, Ho WK, Holliday E, Hopewell J, Hussain M, Iqbal W, Jabeen S, Jannes J, Kamal A, Kamatani Y, Kanse S, Kloss M, Lathrop M, Leys D, Lindgren A, Longstreth WT, Jr., Mahmood K, Meisinger C, Metso TM, Mosley T, Jr., Muller-Nurasyid M, Norrving B, Parati E, Peters A, Pezzini A, Quereshi I, Rasheed A, Rauf A, Salam T, Shen J, Slowik A, Stanne T, Strauch K, Tatlisumak T, Thijs VN, Tiedt S, Traylor M, Waldenberger M, Walters M, Zhao W, Boncoraglio G, Debette S, Jern C, Levi C, Markus H, Meschia J, Rolfs A, Rothwell P, Saleheen D, Seshadri S, Sharma P, Sudlow C, Worrall B, Stine OC, Kittner SJ and Mitchell BD. Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke. PloS one. 2018;13:e0206554.

7.         Sperling C, Maitz MF, Grasso S, Werner C and Kanse SM. A Positively Charged Surface Triggers Coagulation Activation Through Factor VII Activating Protease (FSAP). ACS applied materials & interfaces. 2017;9:40107-40116.

8.         Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C and Farhan H. The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function. EMBO J. 2017;36:260-273.

9.         Kara E, Manna D, Loset GA, Schneider EL, Craik CS and Kanse S. Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates. Thromb Haemost. 2017;117:1750-1760.

10.      Herold J, Nowak S, Kostin S, Daniel JM, Francke A, Subramaniam S, Braun-Dullaeus RC and Kanse SM. Factor VII activating protease (FSAP) influences vascular remodeling in the mouse hind limb ischemia model. Am J Transl Res. 2017;9:3084-3095.

11.      Byskov K, Boettger T, Ruehle PF, Nielsen NV, Etscheid M and Kanse SM. Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells. Atherosclerosis. 2017;265:133-139.

12.      Leiting S, Seidl S, Martinez-Palacian A, Muhl L and Kanse SM. Transforming Growth Factor-beta (TGF-beta) Inhibits the Expression of Factor VII-activating Protease (FSAP) in Hepatocytes. The Journal of biological chemistry. 2016;291:21020-21028.

13.      Daniel JM, Reichel CA, Schmidt-Woell T, Dutzmann J, Zuchtriegel G, Krombach F, Herold J, Bauersachs J, Sedding DG and Kanse SM. Factor VII-activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation. Journal of thrombosis and haemostasis. 2016;14:2058-2067.

14.      Cui XY, Tinholt M, Stavik B, Dahm AE, Kanse S, Jin Y, Seidl S, Sahlberg KK, Iversen N, Skretting G and Sandset PM. Effect of hypoxia on tissue factor pathway inhibitor expression in breast cancer. Journal of thrombosis and haemostasis. 2016;14:387-96.

15.      Chillo O, Kleinert EC, Lautz T, Lasch M, Pagel JI, Heun Y, Troidl K, Fischer S, Caballero-Martinez A, Mauer A, Kurz ARM, Assmann G, Rehberg M, Kanse SM, Nieswandt B, Walzog B, Reichel CA, Mannell H, Preissner KT and Deindl E. Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function. Cell Rep. 2016;16:2197-2207.

16.      Cheng YC, Stanne TM, Giese AK, Ho WK, Traylor M, Amouyel P, Holliday EG, Malik R, Xu H, Kittner SJ, Cole JW, O'Connell JR, Danesh J, Rasheed A, Zhao W, Engelter S, Grond-Ginsbach C, Kamatani Y, Lathrop M, Leys D, Thijs V, Metso TM, Tatlisumak T, Pezzini A, Parati EA, Norrving B, Bevan S, Rothwell PM, Sudlow C, Slowik A, Lindgren A, Walters MR, Consortium W-, Jannes J, Shen J, Crosslin D, Doheny K, Laurie CC, Kanse SM, Bis JC, Fornage M, Mosley TH, Hopewell JC, Strauch K, Muller-Nurasyid M, Gieger C, Waldenberger M, Peters A, Meisinger C, Ikram MA, Longstreth WT, Jr., Meschia JF, Seshadri S, Sharma P, Worrall B, Jern C, Levi C, Dichgans M, Boncoraglio GB, Markus HS, Debette S, Rolfs A, Saleheen D and Mitchell BD. Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2. Stroke. 2016;47:307-16.

17.      Bustamante A, Diaz-Fernandez B, Giralt D, Boned S, Pagola J, Molina CA, Garcia-Berrocoso T, Kanse SM and Montaner J. Factor seven activating protease (FSAP) predicts response to intravenous thrombolysis in acute ischemic stroke. International journal of stroke. 2016;11:646-55.

18.      Subramaniam S, Thielmann I, Morowski M, Pragst I, Sandset PM, Nieswandt B, Etscheid M and Kanse SM. Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP). Thromb Haemost. 2015;113:870-80.

19.      Reichel CA, Hessenauer ME, Pflieger K, Rehberg M, Kanse SM, Zahler S, Krombach F, Berghaus A and Strieth S. Components of the plasminogen activation system promote engraftment of porous polyethylene biomaterial via common and distinct effects. PloS one. 2015;10:e0116883.

20.      Joshi AU, Orset C, Engelhardt B, Baumgart-Vogt E, Gerriets T, Vivien D and Kanse SM. Deficiency of Factor VII activating protease alters the outcome of ischemic stroke in mice. Eur J Neurosci. 2015;41:965-75.

21.      Subramaniam S and Kanse SM. Ferric chloride-induced arterial thrombosis in mice. Curr Protoc Mouse Biol. 2014;4:151-64.

22.      Parahuleva MS, Kanse S, Holschermann H, Zheleva K, Zandt D, Worsch M, Parviz B, Guttler N, Tillmanns H, Boning A and Erdogan A. Association of circulating factor seven activating protease (FSAP) and of oral Omega-3 fatty acids supplements with clinical outcome in patients with atrial fibrillation: the OMEGA-AF study. J Thromb Thrombolysis. 2014;37:317-25.

23.      Martinez-Palacian A, Kanse SM and Weiskirchen R. Factor VII activating protease (FSAP): A novel protective factor in liver fibrosis. Proteomics Clin Appl. 2014;8:438-446.

 

  • Harjen, Hannah Jayne; Hellum, Marit Synnøve; Rørtveit, Runa; Oscarson, Malin; Anfinsen, Kristin Paaske & Moldal, Elena Regine [Show all 9 contributors for this article] (2022). Persistent hypercoagulability in dogs envenomated by the European adder (Vipera berus berus). PLOS ONE. ISSN 1932-6203. 17(2). doi: 10.1371/journal.pone.0263238.
  • Uhl, B; Mittmann, Laura A.; Dominik, Julian; Hennel, Roman; Smiljanov, Bojan & Haring, Florian [Show all 23 contributors for this article] (2021). uPA-PAI-1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils . EMBO Molecular Medicine. ISSN 1757-4676. 13. doi: 10.15252/emmm.202013110. Full text in Research Archive
  • Artunc, Ferruh; Bohnert, Bernhard; Schneider, j; Staudner, Tobias; Sure, Florian & Ilyaskin, a [Show all 15 contributors for this article] (2021). Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice. Pflügers Archiv: European Journal of Physiology. ISSN 0031-6768. doi: 10.1007/s00424-021-02639-7. Full text in Research Archive
  • Gramstad, Olav Rogde; Kandanur, Sai Priya Sarma; Etscheid, Michael; Nielsen, Erik Waage & Kanse, Sandip (2021). Factor VII activating protease (FSAP) is not essential in the pathophysiology of angioedema in patients with C1 inhibitor deficiency. Molecular Immunology. ISSN 0161-5890. 142, p. 95–104. doi: 10.1016/j.molimm.2021.11.019. Full text in Research Archive
  • Cui, Xueyan; Tjønnfjord, Geir Erland; Kanse, Sandip; Dahm, Anders Erik A; Iversen, Nina & Myklebust, Christiane Filion [Show all 12 contributors for this article] (2021). Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia. Scientific Reports. ISSN 2045-2322. 11. doi: 10.1038/s41598-021-84695-8. Full text in Research Archive
  • Zuchtriegel, G.; Uhl, B; Ramsauer, Michaela; Dominik, Julian; Mittmann, L & Canis, Martin [Show all 10 contributors for this article] (2020). Vitronectin stabilizes intravascular adhesion of neutrophils by coordinating beta2 integrin clustering. . Haematologica. ISSN 0390-6078. doi: 10.3324/haematol.2019.226241. Full text in Research Archive
  • Parahuleva, Mariana S; Worsch, M; Euler, Gerhild; Choukeir, Maryana; Mardini, Amar & Parviz, Behnoush [Show all 11 contributors for this article] (2020). Factor VII Activating Protease Expression in Human Platelets and Accumulation in Symptomatic Carotid Plaque. . Journal of the American Heart Association (JAHA). ISSN 2047-9980. 9. doi: 10.1161/JAHA.120.016445. Full text in Research Archive
  • Kara, Emrah; Nielsen, Nis Valentin; Eggertsdottir, Bergrun; Thiede, Bernd; Kanse, Sandip & Løset, Geir Åge (2020). Design and characterization of a new pVII combinatorial phage display peptide library for protease substrate mining using Factor VII activating protease (FSAP) as model. ChemBioChem. ISSN 1439-4227. 21(13), p. 1875–1884. doi: 10.1002/cbic.201900705. Full text in Research Archive
  • Byskov, Kristina; Etscheid, Michael & Kanse, Sandip (2020). Cellular effects of factor VII activating protease (FSAP). Thrombosis Research. ISSN 0049-3848. 188, p. 74–78. doi: 10.1016/j.thromres.2020.02.010. Full text in Research Archive
  • Byskov, Kristina; M. le Gall, Sylvain; Thiede, Bernd; Camerer, Eric & Kanse, Sandip (2019). Protease activated receptors (PAR)‐1 and ‐2 mediate cellular effects of factor VII activating protease (FSAP). The FASEB Journal. ISSN 0892-6638. 34, p. 1079–1090. doi: 10.1096/fj.201801986RR. Full text in Research Archive
  • Bohnert, Bernhard; Daiminger, Sophie; Woern, Matthias; Sure, Florian; Staudner, Tobias & Ilyaskin, Alexandr [Show all 14 contributors for this article] (2019). Urokinase-type Plasminogen Activator (uPA) Is Not Essential for Epithelial Sodium Channel (ENaC)-mediated Sodium Retention in Experimental Nephrotic Syndrome . Acta Physiologica. ISSN 1748-1708. 227(4). doi: 10.1111/apha.13286.
  • Rut, Wioletta; Nielsen, Nis Valentin; Czarna, Justyna; Poreba, Marcin; Kanse, Sandip & Drag, Marcin (2019). Fluorescent Activity-Based Probe for the Selective Detection of Factor VII Activating Protease (FSAP) in Human Plasma. Thrombosis Research. ISSN 0049-3848. 182, p. 124–132. doi: 10.1016/j.thromres.2019.08.016. Full text in Research Archive
  • Ueslue, Ouezguer; Herold, Joerg & Kanse, Sandip (2019). VEGF-A-Cleavage by FSAP and Inhibition of Neo-Vascularization. Cells. ISSN 2073-4409. doi: 10.3390/cells8111396. Full text in Research Archive
  • Nielsen, Nis Valentin; Roedel, Elfie; Manna, Dipankar; Etscheid, Michael; Morth, Jens Preben & Kanse, Sandip (2019). Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP). Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-55531-x. Full text in Research Archive
  • Dahm, Anders Erik A; Jacobsen, Eva-Marie; Wik, Hilde Skuterud; Jacobsen, Anne Flem; Mollnes, Tom Eirik & Kanse, Sandip [Show all 7 contributors for this article] (2019). Elevated complement C3 and C4 levels are associated with postnatal pregnancy-related venous thrombosis. Thrombosis and Haemostasis. ISSN 0340-6245. 119(9), p. 1481–1488. doi: 10.1055/s-0039-1692426. Full text in Research Archive
  • Cole, John W.; Kanse, Sandip; Authors, Other & Mitchell, Braxton (2018). Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke. PLOS ONE. ISSN 1932-6203. doi: 10.1371/journal.pone.0206554. Full text in Research Archive
  • Subramaniam, Saravanan; Kanse, Sandip; Kothari, Hema; Reinhardt, Christoph & Craig, Fletcher (2018). Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood Coagulation and Fibrinolysis. ISSN 0957-5235. 29(8), p. 668–682. doi: 10.1097/MBC.0000000000000775.
  • Praetner, M; Zuchtriegel, G; Holzer, M; Uhl, B; Schaubaecher, J & Mittmann, L [Show all 16 contributors for this article] (2018). Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia-Reperfusion. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 38(4), p. 829–842. doi: 10.1161/ATVBAHA.117.309760.
  • Olsson, Maja; Stanne, Tara M.; Pedersén, Annie; Lorentzen, Erik; Kara, Emrah & Martinez-Palaciàn, Adoraciòn [Show all 14 contributors for this article] (2018). Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity. Journal of Thrombosis and Haemostasis. ISSN 1538-7933. 16(10), p. 2024–2034. doi: 10.1111/jth.14258. Full text in Research Archive
  • Etscheid, Michael; Subramaniam, Saravanan; Lochnit, Guenter; Zabczyk, Michał; Undas, Anetta & Lang, Irene M. [Show all 8 contributors for this article] (2018). Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP). Biochimica et Biophysica Acta. ISSN 0006-3002. 1864(10), p. 3397–3406. doi: 10.1016/j.bbadis.2018.07.030.
  • Cui, Xueyan; Skretting, Grethe; Tinholt, Mari; Stavik, Benedicte; Dahm, Anders Erik A & Kanse, Sandip [Show all 8 contributors for this article] (2017). A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in breast cancer. Research and Practice in Thrombosis and Haemostasis. ISSN 2475-0379. 1, p. 395–395.
  • Sperling, C; Maitz, MF; Grasso, Simona; Werner, C & Kanse, Sandip (2017). A Positively Charged Surface Triggers Coagulation Activation Through Factor VII Activating Protease (FSAP). ACS Applied Materials & Interfaces. ISSN 1944-8244. 9(46), p. 40107–40116. doi: 10.1021/acsami.7b14281. Full text in Research Archive
  • Grasso, Simona; Neumann, A; Lang, IM; Etscheid, Michael; von Köckritz-Blickwede, M & Kanse, Sandip (2017). Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs). Thrombosis Research. ISSN 0049-3848. 161, p. 36–42. doi: 10.1016/j.thromres.2017.11.012. Full text in Research Archive
  • Byskov, Kristina; Boettger, Thomas; Ruehle, Paul F.; Nielsen, Nis Valentin; Etscheid, Michael & Kanse, Sandip (2017). Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells. Atherosclerosis. ISSN 0021-9150. 265, p. 133–139. doi: 10.1016/j.atherosclerosis.2017.08.029. Full text in Research Archive
  • Cui, Xue-Yan; Skretting, Grethe; Tinholt, Mari; Stavik, Benedicte; Dahm, Anders Erik A & Sahlberg, Kristine Kleivi [Show all 9 contributors for this article] (2017). A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in the breast cancer cell line MCF-7. Thrombosis Research. ISSN 0049-3848. 157, p. 111–116. doi: 10.1016/j.thromres.2017.07.013.
  • Herold, Joerg; Nowak, Steven; Kostin, Sawa; Daniel, Jan-Marcus; Francke, Alexander & Subramaniam, Saravanan [Show all 8 contributors for this article] (2017). Factor VII activating protease (FSAP) influences vascular remodeling in the mouse hind limb ischemia model. American journal of translational research. ISSN 1943-8141. 9(6), p. 3084–3095.
  • Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis & Skjelland, Mona [Show all 12 contributors for this article] (2017). Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 491(2), p. 442–448. doi: 10.1016/j.bbrc.2017.07.070.
  • Kara, Emrah; Manna, Dipankar; Løset, Geir Åge; Schneider, E L; Craik, C S & Kanse, Sandip (2017). Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates. Thrombosis and Haemostasis. ISSN 0340-6245. doi: 10.1160/TH17-02-0081. Full text in Research Archive
  • Reiterer-Farhan, Veronika; Figueras‐Puig, Cristina; Le Guerroue,, Francois; Confalonieri, Stefano; Vecchi, Manuela & Jalapothu, Dasaradha [Show all 11 contributors for this article] (2017). The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCFFBXW7 function. EMBO Journal. ISSN 0261-4189. 36(3), p. 260–273. doi: 10.15252/embj.201694795.
  • Bustamante, Alejandro; Diaz-Fernandez, Belen; Giralt, Dolors; Boned, Sandra; Pagola, Jorge & Molina, Carlos [Show all 9 contributors for this article] (2016). Factor seven activating protease (FSAP) predicts response to intravenous thrombolysis in acute ischemic stroke. International Journal of Stroke. ISSN 1747-4930. 11(6), p. 646–655. doi: 10.1177/1747493016641949.
  • Chillo, Omary; Kleinert, Eike Christian; Lautz, Thomas; Lasch, Manuel; Pagel, Judith-Irina & Heun, Yvonn [Show all 20 contributors for this article] (2016). Perivascular mast cells govern shear stress-induced arteriogenesis by orchestrating leukocyte function. Cell reports. ISSN 2211-1247. 16(8), p. 2197–2207. doi: 10.1016/j.celrep.2016.07.040.
  • Daniel, JM; Reichel, Christoph A.; Schmidt-Woell, T.; Dutzmann, J.; Zuchtriegel, G. & Krombach, Fritz [Show all 10 contributors for this article] (2016). Factor VII-activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation. Journal of Thrombosis and Haemostasis. ISSN 1538-7933. 14(10), p. 2058–2067. doi: 10.1111/jth.13417.
  • Leiting, Silke; Seidl, Sebastian; Martinez-Palaciàn, Adoraciòn; Muhl, Lars & Kanse, Sandip (2016). Transforming growth factor-β (TGF-β) inhibits the expression of factor VII-activating protease (FSAP) in hepatocytes. Journal of Biological Chemistry. ISSN 0021-9258. 291(40), p. 21020–21028. doi: 10.1074/jbc.M116.744631.
  • Cheng, Yu-Ching; Stanne, Tara M.; Giese, Anne-Katrin; Ho, Weang Kee; Traylor, Matthew & Amouyel, Philippe [Show all 63 contributors for this article] (2016). Genome-wide association analysis of young-onset stroke identifies a locus on chromosome 10q25 near HABP2. Stroke. ISSN 0039-2499. 47(2), p. 307–316. doi: 10.1161/STROKEAHA.115.011328.
  • Cui, Xue-Yan; Tinholt, Mari; Stavik, Benedicte; Dahm, Anders Erik A; Kanse, Sandip & Jin, Yang [Show all 11 contributors for this article] (2016). Effect of hypoxia on tissue factor pathway inhibitor expression in breast cancer. Journal of Thrombosis and Haemostasis. ISSN 1538-7933. 14(2), p. 387–396. doi: 10.1111/jth.13206.
  • Cui, Xueyan; Tinholt, Mari; Stavik, Benedicte; Dahm, Anders Erik A; Kanse, Sandip & Seidl, Sebastian [Show all 11 contributors for this article] (2015). Effect of hypoxia on tissue factor pathway inhibitor expression in breast cancer cell lines and tissues. Journal of Thrombosis and Haemostasis. ISSN 1538-7933. 13, p. 303–303.
  • Reichel, Christoph A.; Hessenauer, Maximilian E.T.; Pflieger, Kerstin; Rehberg, Markus; Kanse, Sandip & Zahler, Stefan [Show all 9 contributors for this article] (2015). Components of the plasminogen activation system promote engraftment of porous polyethylene biomaterial via common and distinct effects. PLOS ONE. ISSN 1932-6203. 10:e0116883(2). doi: 10.1371/journal.pone.0116883.
  • Joshi, Amit; Orset, Cyrille; Engelhardt, Britta; Baumgart-Vogt, Eveline; Gerriets, Tibo & Vivien, Denis [Show all 7 contributors for this article] (2015). Deficiency of Factor VII Activating Protease (FSAP) alters the outcome of ischemic stroke in mice. European Journal of Neuroscience. ISSN 0953-816X. doi: 10.1111/ejn.12830.
  • Subramaniam, Saravanan; Thielmann, Ina; Morowski, Martina; Pragst, Ingo; Sandset, Per Morten & Nieswandt, Bernhard [Show all 8 contributors for this article] (2015). Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP). Thrombosis and Haemostasis. ISSN 0340-6245. 113(4), p. 870–880. doi: 10.1160/TH14-06-0519.
  • Subramaniam, Saravanan & Kanse, Sandip (2014). Ferric Chloride–Induced Arterial Thrombosis in Mice. Current Protocols in Mouse Biology. ISSN 2161-2617. doi: 10.1002/9780470942390.mo140140.
  • Martinez-Palaciàn, Adoraciòn; Kanse, Sandip & Weiskirchen, Ralf (2014). Factor VII activating protease (FSAP): A novel protective factor in liver fibrosis. PROTEOMICS - Clinical Applications. ISSN 1862-8346. 8(5-6), p. 438–446. doi: 10.1002/prca.201300078.
  • Parahuleva, Mariana S.; Kanse, Sandip; Hölschermann, Hans; Zheleva, Kirila; Zandt, Daniel & Worsch, Michael [Show all 11 contributors for this article] (2014). Association of circulating factor seven activating protease (FSAP) and of oral Omega-3 fatty acids supplements with clinical outcome in patients with atrial fibrillation: the OMEGA-AF study. Journal of Thrombosis and Thrombolysis. ISSN 0929-5305. 37(3), p. 317–325. doi: 10.1007/s11239-013-0921-0.
  • Parahuleva, Mariana S; Ball, N; Parviz, Behnoush; Zandt, Daniel; Abdallah, Yaser & Tillmanns, Harald [Show all 8 contributors for this article] (2013). Factor seven activating protease (FSAP) expression in human placenta and its role in trophoblast migration. European Journal of Obstetrics, Gynecology, and Reproductive Biology. ISSN 0301-2115. 167(1), p. 34–40. doi: 10.1016/j.ejogrb.2012.10.035.
  • Borkham-Kamphorst, Erawan; Zimmermann, Henning W.; Gassler, Nikolaus; Bissels, Ute; Bosio, Andreas & Tacke, Frank [Show all 8 contributors for this article] (2013). Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men. Journal of Hepatology. ISSN 0168-8278. 58(1), p. 104–111. doi: 10.1016/j.jhep.2012.09.007.
  • Parahuleva, Mariana S.; Maj, Robert; Hölschermann, Hans; Parviz, Behnoush; Abdallah, Yaser & Erdogan, Ali [Show all 8 contributors for this article] (2013). Regulation of monocyte/macrophage function by factor VII activating protease (FSAP). Atherosclerosis. ISSN 0021-9150. 230(2), p. 365–372. doi: 10.1016/j.atherosclerosis.2013.08.007.
  • Roedel, Elfie Kathrin; Schwarz, Elisabeth & Kanse, Sandip (2013). The Factor VII-activating Protease (FSAP) Enhances the Activity of Bone Morphogenetic Protein-2 (BMP-2). Journal of Biological Chemistry. ISSN 0021-9258. 288(10), p. 7193–7203. doi: 10.1074/jbc.M112.433029.
  • Etscheid, Michael; Muhl, L.; Pons, D.; Jukema, J. Wouter; Konig, H. & Kanse, Sandip (2012). The Marburg I polymorphism of factor VII activating protease is associated with low proteolytic and low pro-coagulant activity. Thrombosis Research. ISSN 0049-3848. 130(6), p. 935–941. doi: 10.1016/j.thromres.2012.07.023.
  • Hanson, E; Kanse, Sandip; Joshi, A; Jood, K; Nilsson, S & Blomstrand, C [Show all 7 contributors for this article] (2012). Plasma factor VII-activating protease antigen levels and activity are increased in ischemic stroke. Journal of Thrombosis and Haemostasis. ISSN 1538-7933. 10(5), p. 848–856. doi: 10.1111/j.1538-7836.2012.04692.x.
  • Fraineau, Sylvain; Monvoisin, Arnaud; Clarhaut, Jonathan; Talbot, Julie; Simonneau, Claire & Kanthou, Chryso [Show all 9 contributors for this article] (2012). The vitamin K-dependent anti-coagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner. Blood. ISSN 0006-4971. 120(25), p. 5073–5083. doi: 10.1182/blood-2012-05-429183.
  • Huber-Lang, Markus; Denk, Stephanie; Fulda, Simone; Erler, Ellen; Kalbitz, Miriam & Weckbach, Sebastian [Show all 10 contributors for this article] (2012). Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro. Molecular Immunology. ISSN 0161-5890. 50(1-2), p. 60–65. doi: 10.1016/j.molimm.2011.12.005.
  • Parahuleva, Mariana S; Hölschermann, Hans; Zandt, Daniel; Pons-Kühnemann, Jörn; Parviz, Behnoush & Weiskirchen, Ralf [Show all 10 contributors for this article] (2012). Circulating Factor VII Activating Protease (FSAP) Is Associated With Clinical Outcome in Acute Coronary Syndrome. Circulation Journal. ISSN 1346-9843. 76(11), p. 2653–2661. doi: 10.1253/circj.CJ-11-1502.
  • Parahuleva, Mariana S; Langanke, Eva; Hölschermann, Hans; Parviz, Behnoush; Abdallah, Yaser & Stracke, Siegbert [Show all 8 contributors for this article] (2012). Nicotine Modulation of Factor VII Activating Protease (FSAP) Expression in Human Monocytes. Journal of atherosclerosis and thrombosis. ISSN 1880-3873. 19(11), p. 962–969. doi: 10.5551/jat.9589.
  • Reichel, Christoph A.; Kanse, Sandip & Krombach, Fritz (2012). At the Interface of Fibrinolysis and Inflammation: The Role of Urokinase-Type Plasminogen Activator in the Leukocyte Extravasation Cascade. Trends in cardiovascular medicine. ISSN 1050-1738. 22(7), p. 192–196. doi: 10.1016/j.tcm.2012.07.019.
  • Kanse, Sandip; Declerck, Paul J.; Ruf, Wolfram; Broze, George & Etscheid, Michael (2012). Factor VII-Activating Protease Promotes the Proteolysis and Inhibition of Tissue Factor Pathway Inhibitor. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 32(2), p. 427–U619. doi: 10.1161/ATVBAHA.111.238394.
  • Kanse, Sandip; Gallenmueller, Andrea; Zeerleder, Sacha; Stephan, Femke; Rannou, Olivier & Denk, Stephanie [Show all 10 contributors for this article] (2012). Factor VII-Activating Protease Is Activated in Multiple Trauma Patients and Generates Anaphylatoxin C5a. Journal of Immunology. ISSN 0022-1767. 188(6), p. 2858–2865. doi: 10.4049/jimmunol.1103029.
  • Kanse, Sandip; Gallenmueller, Andrea; Zeerleder, Sasha; Stephan, Femke; Rannou, Olivier & Denk, Stephanie [Show all 10 contributors for this article] (2012). Factor VII activating protease (FSAP) is massively activated in multiple trauma patients and generates anaphylatoxin C5a. Journal of Immunology. ISSN 0022-1767. 188(6), p. 2858–2865. doi: 10.4049/jimmunol.1103029.
  • Kanse, Sandip; Declerk, Paul J; Ruf, Wolfram; Broze, George & Etscheid, Michael (2012). Factor VII activating protease (FSAP) promotes the proteolysis and inhibition of tissue factor pathway inhibitor. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 32, p. 427–433. doi: 10.1161/atvbaha.111.238394.

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  • Cui, Xueyan; Tjønnfjord, Geir Erland; Kanse, Sandip; Iversen, Nina; Dahm, Anders Erik A & Myklebust, Christiane Filion [Show all 11 contributors for this article] (2019). Tissue factor pathway inhibitor enhances transendothelial migration of chronic lymphocytic leukemia cells trhough CXCL12/CXCR7 chemotaxis. Research and Practice in Thrombosis and Haemostasis. ISSN 2475-0379. 3.
  • Bohnert, Bernhard; Kanse, Sandip; Haerteis, Silke; Korbmacher, Christoph & Artunc, Ferruh (2019). Rebuttal to Editorial: Sodium Retention by uPA in Nephrotic Syndrome? Acta Physiologica. ISSN 1748-1708. doi: 10.1111/apha.13427.
  • Kara, Emrah; Manna, Dipankar; Løset, Geir Åge; Schneider, Eric L.; Craik, Charles S. & Kanse, Sandip (2017). Analysis of the Substrate Specificity of Factor VII Activating Protease (FSAP) and Design of a Specific and Sensitive Peptide Substrate. Res Pract Thromb Haemost. p. 560–560. doi: 10.1002/rth2.12012.
  • Nielsen, Nis Valentin; Manna, Dipankar; J. Preben, Morth; Roedel, Elfie; Etscheid, Michael & Kanse, Sandip (2017). Factor VII Activating Protease (FSAP) and Marburg I (G534E) Polymorphism; How One Amino Acid Determines Function. Res Pract Thromb Haemost. p. 358–359. doi: 10.1002/rth2.12012.
  • Nielsen, Nis Valentin; Morth, Jens Preben & Kanse, Sandip (2016). Structure function analysis of Factor Seven Activating Protease (FSAP) a protease in vascular biology.
  • Kanse, Sandip (2015). Factor VII activating protease (FSAP):From single nucleotide polymorphisms to mechanisms of action in thrombosis and vascular diseases.
  • Nielsen, Nis Valentin; Morth, Jens Preben & Kanse, Sandip (2015). Expression, Purification and Refolding of Factor Seven Activating Protease(FSAP) for structure function analysis.
  • Nielsen, Nis Valentin; Morth, Jens Preben & Kanse, Sandip (2015). Purification and refolding of Factor Seven Activating Protease (FSAP) a protease in vascular biology.
  • Nielsen, Nis Valentin; Morth, Jens Preben & Kanse, Sandip (2015). Purification and refolding of Factor Seven Activating Protease (FSAP) a protease in vascular biology.

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Published Jan. 12, 2012 2:25 PM - Last modified Dec. 12, 2019 1:11 PM