Torkel Hafting

Image of Torkel Hafting
Norwegian version of this page
Room L-161
Username
Visiting address Domus Medica
Postal address Postboks 1103 Blindern 0317 Oslo

Academic Interests

  • Systems neuroscience: neural circuits & behaviour
  • Spatial and social memory
  • Perception
Photo of perineuronal nets stabilize long-term memories
Some neurons are surrounded by a dense sugar coat, perineuronal nets (green) which limits plasticity in the adult brain. Bottom row show the development of the nets from postnatal day 12 to 30 in entorhinal cortex. Synapses on the cell body are located in the holes in the nets (Christensen, Lensjø et al., 2017). 
Perineuronal nets stabilize long-term memories (Thompson et al., PNAS 2018).
Perineuronal nets stabilize the grid cell network. (Christensen et al., Nature Communications 2021).

Teaching

Higher education and employment history

Education:

  • 2005: Dr.Scient. in physiology, University of Oslo.
  • 1998: MSc in physiology, University of Oslo.
  • 1996: Arctic biology, The Unversity Center in Svalbard.
  • 1995: Bachelor in Biology, University of Oslo.

Positions:

  • 2010-2013: Group leader, Institute of Biosciences, UiO
  • 2008-2010:  Postoc, University of California San Francisco
  • 2002-2008: Postdoc, Centre for the Biology of Memory, NTNU

Honoraria

  • 2008: Fulbright scholar fellowship.
  • 2007: Nansen-award. Norwegian Academy of Sciences and Letters prize for young researchers.
  • 2006: I.K. Lykkes award. Royal Norwegian Society of Sciences and Letters prize for young researchers in natural Sciences.

Collaboration

Tags: Brain and nervous system, Neuroscience, Life science, Memory, Cortex, Plasticity

Publications

  • Beshkov, Kosio; Fyhn, Marianne; Hafting, Torkel & Einevoll, Gaute Tomas (2023). Topological Structure of Population Activity in Mouse Visual Cortex Encodes Densely Sampled Visual Scene Rotations. Social Science Research Network (SSRN). ISSN 1556-5068. doi: 10.2139/ssrn.4495668.
  • Lepperød, Mikkel Elle; Stöber, Tristan Manfred; Hafting, Torkel; Fyhn, Marianne & Kording, Konrad Paul (2023). Inferring causal connectivity from pairwise recordings and optogenetics. PLoS Computational Biology. ISSN 1553-734X. 19(11). doi: 10.1371/journal.pcbi.1011574. Full text in Research Archive
  • Hanssen, Kine Ødegård; Grødem, Sverre; Fyhn, Marianne; Hafting, Torkel; Einevoll, Gaute & Ness, Torbjørn V [Show all 7 contributors for this article] (2023). Responses in fast-spiking interneuron firing rates to parameter variations associated with degradation of perineuronal nets. Journal of Computational Neuroscience. ISSN 0929-5313. 51, p. 283–298. doi: 10.1007/s10827-023-00849-9. Full text in Research Archive
  • Hanssen, Kine Ødegård; Grødem, Sverre; Fyhn, Marianne; Hafting, Torkel; Einevoll, Gaute & Ness, Torbjørn Vefferstad [Show all 7 contributors for this article] (2022). Effects of perineuronal nets on neural ring properties. Research Square. ISSN 2693-5015. doi: 10.21203/rs.3.rs-2198467/v1.
  • Lehr, Andrew; Kumar, Arvind; Tezlaff, Christian; Hafting, Torkel; Fyhn, Marianne & Stöber, Tristan Manfred (2021). CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing. Neuroscience and Biobehavioral Reviews. ISSN 0149-7634. 126, p. 398–412. doi: 10.1016/j.neubiorev.2021.03.020. Full text in Research Archive
  • Lepperød, Mikkel Elle; Christensen, Ane Charlotte; Lensjø, Kristian Kinden; Buccino, Alessio Paolo; Yu, Jai & Fyhn, Marianne [Show all 7 contributors for this article] (2021). Optogenetic pacing of medial septum parvalbumin-positive cells disrupts temporal but not spatial firing in grid cells. Science Advances. ISSN 2375-2548. 7(19). doi: 10.1126/sciadv.abd5684. Full text in Research Archive
  • Christensen, Ane Charlotte; Lensjø, Kristian Kinden; Lepperød, Mikkel Elle; Dragly, Svenn-Arne; Sutterud, Hallvard & Blackstad, Jan Sigurd [Show all 8 contributors for this article] (2021). Perineuronal nets stabilize the grid cell network. Nature Communications. ISSN 2041-1723. 12. doi: 10.1038/s41467-020-20241-w. Full text in Research Archive
  • Stöber, Tristan Manfred; Lehr, Andrew B; Hafting, Torkel; Kumar, Arvind & Fyhn, Marianne (2020). Selective neuromodulation and mutual inhibition within the CA3-CA2 system can prioritize sequences for replay. Hippocampus. ISSN 1050-9631. doi: 10.1002/hipo.23256. Full text in Research Archive
  • Lepperød, Mikkel Elle; Dragly, Svenn-Arne; Buccino, Alessio Paolo; Mobarhan, Milad; Malthe-Sørenssen, Anders & Hafting, Torkel [Show all 7 contributors for this article] (2020). Experimental Pipeline (Expipe): A Lightweight Data Management Platform to Simplify the Steps From Experiment to Data Analysis. Frontiers in Neuroinformatics. ISSN 1662-5196. 14. doi: 10.3389/fninf.2020.00030. Full text in Research Archive
  • Raheel, Tayyaba Qureshi; Sørensen, Christina; Berghuis, Paul; Jensen, Vidar; Dobszay, Marton B. & Farkas, Tamás [Show all 14 contributors for this article] (2019). The glutamine transporter Slc38a1 regulates GABAergic neurotransmission and synaptic plasticity. Cerebral Cortex. ISSN 1047-3211. 29(12), p. 5166–5179. doi: 10.1093/cercor/bhz055. Full text in Research Archive
  • Christensen, Ane Charlotte; Lepperød, Mikkel; Lensjø, Kristian Kinden; Dragly, Svenn-Arne; Blackstad, Jan Sigurd Beddari & Fyhn, Marianne [Show all 7 contributors for this article] (2019). Perineuronal nets stabilize the grid cell network. bioRxiv. ISSN 2692-8205. doi: 10.1101/796342.

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  • Beshkov, Kosio; Fyhn, Marianne; Hafting, Torkel & Einevoll, Gaute Tomas (2023). Topological Structure of Population Activity in Mouse Visual Cortex Encodes Densely Sampled Visual Scene Rotations.
  • Beshkov, Kosio; Fyhn, Marianne; Hafting, Torkel & Einevoll, Gaute Tomas (2023). Topological Structure of Population Activity in Mouse Visual Cortex Encodes Densely Sampled Visual Scene Rotations.
  • Elle Lepperød, Mikkel; Stöber, Tristan; Hafting, Torkel; Fyhn, Marianne & Kording, Konrad (2022). Inferring causal connectivity from pairwise recordings and optogenetics. bioRxiv. ISSN 2692-8205. doi: 10.1101/463760.
  • Annavini, Eis; Korchynska, Solomiia; Babursah, Ela; Hafting, Torkel & Boccara, Charlotte (2022). A benchmark for sharp wave-ripple detection algorithms.
  • Thon, Sarah Kriebel; Christensen, Ane Charlotte; Fjeldstad, Maria P; Schøyen, Vemund Sigmundson; Olsen, Elise Reppe & Lepperød, Mikkel Elle [Show all 8 contributors for this article] (2022). Social and spatial codes in hippocampus CA2 and entorhinal cortex.
  • Sørensen, Christina; Qureshi, Tayyaba; Fyhn, Marianne; Hafting, Torkel & Chaudhry, Farrukh Abbas (2021). GABA er essensielt for normal hjerneutvikling og synaptisk plastisitet. NBS-nytt. ISSN 0801-3535.
  • Hafting, Torkel (2021). Dissociation between theta oscillations and the spatial code of grid cells.
  • Røe, Malin Benum; Aasebø, Ida Elisabeth Jørgensen; Mobarhan, Milad; Lensjø, Kristian Kinden; Einevoll, Gaute & Hafting, Torkel [Show all 7 contributors for this article] (2019). Stable orientation tuning in the freely moving rat: Movement-robust orientation-selective neurons in the deep layers of the primary visual cortex.
  • Røe, Malin Benum; Aasebø, Ida Elisabeth Jørgensen; Mobarhan, Milad; Lensjø, Kristian Kinden; Einevoll, Gaute & Hafting, Torkel [Show all 7 contributors for this article] (2019). Stable orientation tuning in the freely moving rat: Movement-robust orientation-selective neurons in the deep layers of the primary visual cortex.

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Published Nov. 11, 2013 9:41 AM - Last modified Jan. 10, 2023 12:56 PM