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Autophagy

 

Dysfunctional autophagy is linked to several pathophysiological conditions, including cancer and neurodegenerative disorders.⁠ The main focus of the “Simonsen Lab” is to characterize of the molecular mechanisms involved in cargo sequestration and autophagosome biogenesis during non-selective and selective types of autophagy with a long-term goal to identify novel targets for diagnosis or treatment of human disease.

Science group

The Simonsen Lab 2019 (form left): Matthew Yoke Wui Ng, Chara Charsou, Gunnveig T Bjørndal, Anne Simonsen, Laura Trachsel Moncho, Ana Lapao, Camilla Bergsmark, Kristiane Søreng, Serhiy Pankiv, Lauara Rodriguez de la ballina, Nagham T Asp, Alf Håkon Lystad, Benan John Mathai. Not present: Aleksander Aas. Foto: Sigmund Karlsen.

About the group

Work in our laboratory is currently focused on identification of novel lipid-binding proteins involved in different types of autophagy and elucidation of their function in autophagy and link to disease. To address these challenges, we use a combination of cell biological, biochemical, imaging, genomic and computational approaches, as well as disease-related model systems.

Illustrasjon

Research Projects

Our research is funded by

  • The University of Oslo
  • The Research Council of Norway
  • The Norwegian Cancer Society
  • H-2020 MSC COFUND and ITN actions
Published Feb. 23, 2011 3:12 PM - Last modified Aug. 22, 2020 3:32 PM

Contact

Mailing address
P.O.Box 1112 Blindern
0317 Oslo

Visiting address
Domus Medica, Gaustad
Sognsvannsveien 9
0372 Oslo

Group leader