Nansen Neuroscience Lecture 2019

The Nansen Neuroscience Lectures (NNL) honour Nansen’s ground-breaking contribution to neuroscience and since 10.10.2010 are part of the Academy’s Nansen celebration. This year, Morten Scheibye-Knudsen, Center for Healthy Aging (CEHA), University of Copenhagen, will speak on "Discovering interventions for healthier, happier and more productive ageing".

Open to public, no charge  

Impaired health at old age is a major societal concern. Dr Morten Scheibye-Knudsen, uses in silico analyses, artificial intelligence, in vitro biochemistry and molecular biology as well as in vivo work on mouse disease models to provide new understanding and novel approaches to prevention and therapy.

Programme

11:30 - 12:00 Coffee and refreshments - mingling.

12:00 - 12:03 Opening by Hans Petter Graver, President of The Norwegian Academy of   Science and Letters.

12:03 - 12:06 Introduction by Linda H. Bergersen, University of Oslo.

12:06 - 12:46 "Discovering interventions for healthier, happier and more productive ageing", lecture by Morten Scheibye-Knudsen, University of Copenhagen, Denmark.

12:46 - 13:00 Discussion and questions from the audience, moderator Jon Storm-Mathisen, University of Oslo.

13:00 - 13:30 Coffee and refreshments – informal discussions.

Biography: Morten Scheibye-Knudsen

Morten Scheibye-Knudsen is an Associate Professor at the Department of Cellular and Molecular Medicine and at the Center for Healthy Aging (CEHA), University of Copenhagen. He did his MD at the University of Copenhagen and worked briefly as a physician in Denmark and Greenland before turning to science. He did his post-doctoral fellowship at Vilhelm Bohr’s lab at the National Institute on Aging, National Institutes of Health, where he utilized state-of-the art approaches to understand how DNA damage contributes to aging.

Professor
Associate professor Morten Scheibye-Knudsen, Center for Healthy Aging (CEHA), University of Copenhagen.  

 

He discovered that neurodegeneration in several premature aging diseases is partly caused by hyperactivation of a DNA damage responsive enzyme called polyADP-ribose polymerase 1 (PARP1). This activation leads to loss of vital metabolites such as NAD+ and acetyl-CoA. Importantly, this discovery facilitated the realization that we can intervene in the aging process by inhibiting PARP1, augmenting NAD+ levels and increasing acetyl-CoA. In his own lab he continues to focus on understanding aging by combining machine learning based approaches with wet-lab analyses with the goal of developing interventions for age-associated diseases and perhaps aging itself.

Scheibye-Knudsen Group

Primary field of research Scheibye-Knudsen

The arrangement takes place at The Norwegian Academy of Science and Letters.

Organizer

Linda H Bergersen and Jon Storm-Mathisen at the University of Oslo, the Nansen Neuroscience Network (NNN) and Norwegian Academy of Science and Letters (DNVA)
Published Oct. 9, 2019 3:29 PM - Last modified Oct. 10, 2019 9:13 AM