Alexandre Corthay

Forsker - Senter for fremragende forskning Senter for biohybridteknologi
Bilde av Alexandre Corthay
English version of this page
Telefon 23074109
Rom A3.M018
Brukernavn
Besøksadresse Rikshospitalet Avdeling for patologi

Faglige interesser

Immunologi, kreft, immunterapi

Nettsider

Senter for fremragende forskning - Senter for biohybridteknologi

Tumorimmunologi-gruppen

Verv

Associate Editor for Scandinavian Journal of Immunology and Frontiers in Immunology

Emneord: Immunologi, Kreftforskning, immunterapi

Publikasjoner

  • Frafjord, Astri; Skarshaug, Renate; Hammarström, Clara Louise; Stankovic, Branislava; Dorg, Linda Trobe; Aamodt, Henrik; Woldbæk, Per R; Helland, Åslaug; Brustugun, Odd Terje; Øynebråten, Inger & Corthay, Alexandre (2020). Antibody combinations for optimized staining of macrophages in human lung tumours. Scandinavian Journal of Immunology.  ISSN 0300-9475.  92:e12889(1), s 1- 24 . doi: 10.1111/sji.12889 Fulltekst i vitenarkiv.
  • Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Brinch, Shoshy Alam; Lycke, Max; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre & Krauss, Stefan (2020). Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology.  ISSN 2399-3642.  3(196) . doi: 10.1038/s42003-020-0916-2
  • Haabeth, Ole Audun; Fauskanger, Marte; Manzke, Melanie; Lundin, Katrin; Corthay, Alexandre; Bogen, Bjarne & Tveita, Anders (2018). CD4+ T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs. Cancer Research.  ISSN 0008-5472.  78(16), s 4573- 4585 . doi: 10.1158/0008-5472.CAN-17-2426
  • Müller, Elisabeth; Speth, Martin; Christopoulos, Panagiotis; Lunde, Anna; Avdagic, Ajna; Øynebråten, Inger & Corthay, Alexandre (2018). Both type I and type II interferons can activate antitumor M1 macrophages when combined with TLR stimulation. Frontiers in Immunology.  ISSN 1664-3224.  9, s 1- 16 . doi: 10.3389/fimmu.2018.02520 Fulltekst i vitenarkiv.
  • Stankovic, Branislava; Bjørhovde, Heidi Anine Korsmo; Skarshaug, Renate; Aamodt, Henrik; Frafjord, Astri; Müller, Elisabeth; Hammarström, Clara Louise; Beraki, Kahsai; Bækkevold, Espen Sønderaal; Woldbæk, Per R; Helland, Åslaug; Brustugun, Odd Terje; Øynebråten, Inger & Corthay, Alexandre (2018). Immune Cell Composition in Human Non-small Cell Lung Cancer. Frontiers in Immunology.  ISSN 1664-3224.  Feb(1), s 1- 21 . doi: 10.3389/fimmu.2018.03101 Fulltekst i vitenarkiv. Vis sammendrag
  • Anderson, Colin C.; Bretscher, Peter; Corthay, Alexandre; Dembic, Zlatko; Havele, Calliopi; Nagy, Zoltan A. & Øynebråten, Inger (2017). Immunological Tolerance. Part I of a Report of a Workshop on Foundational Concepts of Immune Regulation. Scandinavian Journal of Immunology.  ISSN 0300-9475.  85(2), s 84- 94 . doi: 10.1111/sji.12500
  • Bretscher, Peter; Corthay, Alexandre; Anderson, Colin C.; Dembic, Zlatko; Havele, Calliopi; Nagy, Zoltan A. & Øynebråten, Inger (2017). Immune Class Regulation and Its Medical Significance Part II of a Report of a Workshop on Foundational Concepts of Immune Regulation. Scandinavian Journal of Immunology.  ISSN 0300-9475.  85(4), s 242- 250 . doi: 10.1111/sji.12525 Vis sammendrag
  • Christopoulos, Panagiotis; Corthay, Alexandre & Koutsilieris, Michael (2017). Aiming for the Insulin-like Growth Factor-1 system in breast cancer therapeutics. Cancer Treatment Reviews.  ISSN 0305-7372.  63, s 79- 95 . doi: 10.1016/j.ctrv.2017.11.010
  • Kurena, Baiba; Müller, Elisabeth; Christopoulos, Panagiotis; Johnsen, Ingvild Bjellmo; Stankovic, Branislava; Øynebråten, Inger; Corthay, Alexandre & Zajakina, Anna (2017). Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ. Frontiers in Immunology.  ISSN 1664-3224.  8 . doi: 10.3389/fimmu.2017.01667 Fulltekst i vitenarkiv.
  • Müller, Elisabeth; Christopoulos, Panagiotis; Halder, Sanjib; Lunde, Anna; Beraki, Kahsai; Speth, Martin; Øynebråten, Inger & Corthay, Alexandre (2017). Toll-like receptor ligands and interferon-gamma synergize for induction of antitumor M1 macrophages. Frontiers in Immunology.  ISSN 1664-3224.  8 . doi: 10.3389/fimmu.2017.01383 Fulltekst i vitenarkiv.
  • Obando, Daniel F. González; Frafjord, Astri; Øynebråten, Inger; Corthay, Alexandre; Olivo-Marin, Jean-Christophe & Meas-Yedid, Vannary (2017). Multi-staining registration of large histology images. IEEE International Symposium on Biomedical Imaging.  ISSN 1945-7928.  s 345- 348 . doi: 10.1109/ISBI.2017.7950534
  • Speth, Martin; Repnik, Urska; Müller, Elisabeth; Spanier, Julia; Kalinke, Ulrich; Corthay, Alexandre & Griffiths, Gareth Wyn (2017). Poly(I:C)-Encapsulating Nanoparticles Enhance Innate Immune Responses to the Tuberculosis Vaccine Bacille Calmette-Guerin (BCG) via Synergistic Activation of Innate Immune Receptors. Molecular Pharmaceutics.  ISSN 1543-8384.  14(11), s 4098- 4112 . doi: 10.1021/acs.molpharmaceut.7b00795
  • Wold, Christian Winther; Kjeldsen, Christian; Corthay, Alexandre; Rise, Frode; Christensen, Bjørn E.; Duus, Jens Øllgaard & Inngjerdingen, Kari Tvete (2017). Structural characterization of bioactive heteropolysaccharides from the medicinal fungus Inonotus obliquus (Chaga).. Carbohydrate Polymers.  ISSN 0144-8617.  185, s 27- 40 . doi: 10.1016/j.carbpol.2017.12.041 Fulltekst i vitenarkiv.
  • Andersen, Aram Nikolai; Landsverk, Ole J. B.; Simonsen, Anne; Bogen, Bjarne; Corthay, Alexandre & Øynebråten, Inger (2016). Coupling of HIV-1 antigen to the selective autophagy receptor SQSTM1/p62 promotes T-cell-mediated immunity. Frontiers in Immunology.  ISSN 1664-3224.  7 . doi: 10.3389/fimmu.2016.00167 Fulltekst i vitenarkiv.
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Yagita, Hideo; Bogen, Bjarne & Corthay, Alexandre (2016). Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells. Oncoimmunology.  ISSN 2162-4011.  5(1) . doi: 10.1080/2162402X.2015.1039763
  • Joly-Battaglini, Albane; Hammarström, Clara Louise; Stankovic, Branislava; Aamodt, Henrik; Stjärne, Johan Folke Håkan; Brustugun, Odd Terje; Helland, Åslaug; Øynebråten, Inger & Corthay, Alexandre (2016). Rituximab efficiently depletes B cells in lung tumors and normal lung tissue. F1000.  ISSN 1759-796X.  5 . doi: 10.12688/f1000research.7599.1
  • Lorvik, Kristina Berg; Hammarström, Clara Louise; Fauskanger, Marte; Haabeth, Ole Audun; Zangani, Michael M; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2016). Adoptive transfer of tumor-specific Th2 cells eradicates tumors by triggering an in situ inflammatory immune response. Cancer Research.  ISSN 0008-5472.  76(23), s 6864- 6876 . doi: 10.1158/0008-5472.CAN-16-1219
  • Corthay, Alexandre (2014). Does the immune system naturally protect against cancer?. Frontiers in Immunology.  ISSN 1664-3224.  5(MAY) . doi: 10.3389/fimmu.2014.00197
  • Haabeth, Ole Audun; Tveita, Anders; Fauskanger, Marte Hotvedt; Schjesvold, Fredrik Hellem; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde; Munthe, Ludvig Andre; Dembic, Zlatko; Corthay, Alexandre & Bogen, Bjarne (2014). How do CD4+ T cells detect and eliminate tumor cells that either lack or express MHC class II molecules?. Frontiers in Immunology.  ISSN 1664-3224.  5:174 . doi: 10.3389/fimmu.2014.00174 Fulltekst i vitenarkiv.
  • Lorvik, Kristina Berg; Haabeth, Ole Audun; Clancy, Trevor; Bogen, Bjarne & Corthay, Alexandre (2013). Molecular profiling of tumor-specific T(H)1 cells activated in vivo. Oncoimmunology.  ISSN 2162-4011.  2(5:e24383) . doi: 10.4161/onci.24383
  • Berge, Tone; Grønningsæter, Ingrid Helene; Lorvik, Kristina Berg; Abrahamsen, Greger; Granum, Stine; Gjerstad, Vibeke Sundvold; Corthay, Alexandre; Bogen, Bjarne & Spurkland, Anne (2012). SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice. PLOS ONE.  ISSN 1932-6203.  7(10)
  • Haabeth, Ole Audun; Bogen, Bjarne & Corthay, Alexandre (2012). A model for cancer-suppressive inflammation. Oncoimmunology.  ISSN 2162-4011.  1(7), s 1146- 1155 . doi: 10.4161/onci.21542
  • Corthay, Alexandre; Lorvik, Kristina Berg & Bogen, Bjarne (2011). Is Secretion of Tumour-specific Antigen Important for Cancer Eradication by CD4+T Cells? - Implications for Cancer Immunotherapy by Adoptive T Cell Transfer. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(6), s 527- 530 . doi: 10.1111/j.1365-3083.2011.02558.x
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarstrøm, Clara Louise; Donaldson, Ian Matthew; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2011). Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer. Nature Communications.  ISSN 2041-1723.  2 . doi: 10.1038/ncomms1239
  • Corthay, Alexandre; Lundin, Katrin; Lorvik, Kristina Berg; Hofgaard, Peter Olaf & Bogen, Bjarne (2009). Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4(+) T Cells. Cancer Research.  ISSN 0008-5472.  69(14), s 5901- 5907 . doi: 10.1158/0008-5472.CAN-08-4816
  • Funderud, Ane; Aas-Hanssen, Kristin; Aksaas, Anne Kristin; Hafte, Tolesa Tilahun; Corthay, Alexandre; Munthe, Ludvig Andre; Ørstavik, Sigurd & Skålhegg, Bjørn Steen (2009). Isoform-specific regulation of immune cell reactivity by the catalytic subunit of protein kinase A (PKA). Cellular Signalling.  ISSN 0898-6568.  21(2), s 274- 281 . doi: 10.1016/j.cellsig.2008.10.013
  • Corthay, Alexandre (2007). CD4+T cells cooperate with macrophages for specific elimination of MHC class II-negative cancer cells. Advances in Experimental Medicine and Biology.  ISSN 0065-2598.  590, s 195- 208
  • Bogen, Bjarne; Ruffini, Pier Adelchi; Corthay, Alexandre; Brunsvik, Agnete; Frøyland, Marianne; Lundin, Katrin; Røsjø, Egil; Thompson, Keith & Massaia, M (2006). Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research. Studies in Surface Science and Catalysis.  ISSN 0167-2991.  91, s 941- 948
  • Munthe, Ludvig Andre; Corthay, Alexandre; Os, Audun; Zangani, Michael M & Bogen, Bjarne (2005). Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from immunoglobulin V region-specific T cells. Journal of Immunology.  ISSN 0022-1767.  175, s 2391- 2400 . doi: 16081810
  • Corthay, Alexandre; Skovseth, Dag Kristian; Lundin, Katrin; Røsjø, Egil; Omholt, Hilde; Hofgaard, Peter Olaf; Haraldsen, Guttorm & Bogen, Bjarne (2005). Primary antitumor immune response mediated by CD4+ T cells. Immunity.  ISSN 1074-7613.  22, s 371- 383
  • Corthay, Alexandre; Lundin, Katrin; Munthe, Ludvig Andre; Frøyland, Marianne; Gedde-Dahl, Thobias; Dembic, Zlatko & Bogen, Bjarne (2004). Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models. Cancer Immunology and Immunotherapy.  ISSN 0340-7004.  53, s 759- 769
  • Tjelle, TE; Corthay, Alexandre; Lunde, Elin; Sandlie, Inger; Michaelsen, Terje Einar; Mathiesen, I & Bogen, Bjarne (2004). Monoclonal antibodies produced by muscle after plasmid injection and electroporation. Molecular Therapy.  ISSN 1525-0016.  9(3), s 328- 336

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  • Corthay, Alexandre (2017). Book Review: The foundations of immunology and their pertinence to medicine. Scandinavian Journal of Immunology.  ISSN 0300-9475.  86(2), s 119- 120 . doi: 10.1111/sji.12565
  • Corthay, Alexandre (2016). Book Review: Rediscovering the Immune System as an Integrated Organ. Scandinavian Journal of Immunology.  ISSN 0300-9475.  84(1), s 70- 71 . doi: 10.1111/sji.12440
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara Louise; Donaldson, Ian M; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2016). Kreft-spesifikke betennelsesreaksjoner kan beskytte mot kreft. BestPractice. Onkologi Hematologi.  February
  • Corthay, Alexandre & Stankovic, Branislava (2015). Characterization of immune cells in human non-small cell lung cancer (Thesis for the Master’s Degree in Molecular Biosciences).
  • Joly-Battaglini, A & Corthay, Alexandre (2015). Study of immune cells infiltrating human non-small cell lung cancer (Thesis for the Master’s Degree in Biology).
  • Müller, Elisabeth; Stavna, A.; Jahnsen, Frode Lars; Bakke, Oddmund & Corthay, Alexandre (2013). Using Live Imaging to Investigate the Mechanisms Underlying Tumor Cell Killing by Macrophages. Scandinavian Journal of Immunology.  ISSN 0300-9475.  77(4), s 275- 276
  • Corthay, Alexandre; Hammarström, Clara; Fauskanger, M.; Haabeth, OAW; Zangani, Miriam; Haraldsen, H.; Bogen, Bjarne & Lorvik, Kristina Berg (2012). Cancer immunotherapy by adoptive transfer of tumor-specific Th2 cells. Immunology.  ISSN 0019-2805.  137, s 706- 706
  • Lorvik, Kristina Berg; Bogen, Bjarne & Corthay, Alexandre (2012). Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice. Blood.  ISSN 0006-4971.  119(9), s 2176- 2177 . doi: 10.1182/blood-2011-10-388892
  • Alfsnes, Katrine; Lorvik, Kristina Berg; Audun, Ole; Haabeth, Werner; Bogen, Bjarne & Corthay, Alexandre (2011). Workshop IV - Tumor Immunology and Infectious Diseases Immunology. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 380- 380
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarstrom, C; Donaldson, Ian Matthew; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2011). A cancer-protective role of inflammation. Cytokine.  ISSN 1043-4666.  56(1), s 101- 101 . doi: 10.1016/j.cyto.2011.07.392
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara; Donaldson, Ian Matthew; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2011). Cancer Immunosurveillance by CD4(+) T Cells. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(6), s 603- 603
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara; Donaldson, Ian Matthew; Haraldsen, Guttorm; Bogen, Bjarne & Corthay, Alexandre (2011). Inflammation Driven by Tumor-Specific Th1 Cells Protects against B-Cell Cancer. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 384- 384
  • Lorvik, Kristina Berg; Zangani, Michael Mehrdad; Bogen, Bjarne & Corthay, Alexandre (2011). Myeloma Immunotherapy by Adoptive Transfer of Idiotype-Specific Th2 Cells. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 392- 392
  • Corthay, Alexandre (2009). How do Regulatory T Cells Work?. Scandinavian Journal of Immunology.  ISSN 0300-9475.  70(4), s 326- 336 . doi: 10.1111/j.1365-3083.2009.02308.x
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Bogen, Bjarne & Corthay, Alexandre (2009). Cytokine profile of successful cancer immunosurveillance mediated by tumor-specific CD4(+) T cells. Cytokine.  ISSN 1043-4666.  48(1-2), s 48- 48 . doi: 10.1016/j.cyto.2009.07.135
  • Corthay, Alexandre; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde & Bogen, Bjarne (2008). Transcriptomics of a successful antitumor immune response. Scandinavian Journal of Immunology.  ISSN 0300-9475.  68, s 209- 209
  • Haabeth, OAW; Lorvik, Kristina Berg; Aagaard, L; Bogen, Bjarne & Corthay, Alexandre (2008). Role of cytokines and chemokines for cancer immune prevention. Scandinavian Journal of Immunology.  ISSN 0300-9475.  68, s 218- 218
  • Lorvik, Kristina Berg; Corthay, Alexandre; Lundin, Katrin; Hofgaard, Peter Olaf; Omholt, Hilde & Bogen, Bjarne (2008). Role of antigen secretion for cancer immunosurveillance. Scandinavian Journal of Immunology.  ISSN 0300-9475.  68, s 217- 218
  • Corthay, Alexandre (2006). A three-cell model for activation of naive T helper cells. Scandinavian Journal of Immunology.  ISSN 0300-9475.  64, s 93- 96
  • Halstensen, Trond Sundby; Corthay, Alexandre & Westgaard, Arne (2005, 29. april). Immunologiens dag 29. april 2005 - populærvitenskapelig konferanse i universitetets aula. [Internett].  Norsk Selskap for Immunologi - www.norwegianimmunology.org. Vis sammendrag
  • Halstensen, Trond Sundby; Westgaard, Arne & Corthay, Alexandre (2005, 18. november). NSI's Annual General Meeting 2005. [Internett].  Abstraktbok utgitt i papirform.

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Publisert 2. des. 2019 12:47 - Sist endret 6. jan. 2020 16:32