ebrinch

Bilde av person
Kan ikke hente personopplysninger fra ekstern kilde

Faglige interesser

  • Stamcellebiologi
  • Vevsregenerativ behandling
  • Celleterapi

Undervisning

PBL

Bakgrunn

Utdanning:

  • 1991: PhD i HIV immunologi and virologi, Universitet i Oslo
  • 1987: Spesialist i indremedisin
  • 1976: MD, Royal College of Surgeons in Ireland

Arbeidserfaring:

  • 2009 - Gruppeleder, Nasjonalt senter for stamcelleforskning, OUS Rikshospitalet og UiO
  • 2005 - Seksjonsleder Celleterapi, Immunologisk institutt, OUS Rikshospitalet
  • 1998 - 2005 Laboratoriesjef, Ex vivo cellelaboratoriet, OUS Rikshospitalet
  • 1995 - 2005 Forsker, Immunologisk institutt, OUS Rikshospitalet
  • 1992 - 1995 Postdoktor, Immunologisk institutt, OUS Rikshospitalet
  • 1986 - 1991 PhD stipendiat, Immunologisk institutt, OUS Rikshospitalet
  • 1985 - 1986 Assistentlege, Medisinsk avdeling, AHUS
  • 1982 - 1985 Reservelege, Medisinsk avdeling, Woden Valley Hospital og Royal Canberra Hospital, Canberra, Australia
  • 1979 - 1982 Assistentlege, Infeksjonsmedisinsk avdeling, Ullevål sykehus

Priser

  • 1990: Domagk-Bayer pris for beste infeksjonsmedisinske publikasjon, NOK 10.000
  • 1991: Medinnova idépris, NOK 100.000

Samarbeid

  • Nasjonalt senter for stamcelleforskning, Jan E. Brinchmann gruppen
  • Avdeling for immunologi, OUS Rikshospitalet
  • Professor Lars Engebretsen, Avdeling for ortopedi, OUS Ullevål sykehus
  • Dr. Svend Aakhus, Avdeling for hjertesykdommer, OUS Rikshospitalet
  • Professor Philippe Collas, Avdeling for biokjemi, Institutt for medisinske basalfag, UiO
  • Dr. Leonardo Meza-Zepeda, Microarray Kjernefacilitet, OUS Radiumhospitalet
  • Dr. Tarjei Mikkelsen, Broad Institute, Massachusetts Institute of Technology og Harvard Stem Cell Institute
Emneord: Stamceller, Muskel og skjelett, Hjerte kar og lunger

Publikasjoner

  • Frerker, Nadine; Karlsen, Tommy Aleksander; Lilledahl, Magnus Borstad; Brorson, Sverre Henning; Tibballs, John Earl & Brinchmann, Jan E. (2021). Scaffold-Free Engineering of Human Cartilage Implants. Cartilage. ISSN 1947-6035. doi: 10.1177/19476035211007923.
  • Al-Modawi, Rua Nader; Brinchmann, Jan E. & Karlsen, Tommy Aleksander (2019). Multi-pathway protective effects of microRNAs on human chondrocytes in an in vitro model of osteoarthritis. Molecular Therapy - Nucleic Acids. ISSN 2162-2531. 17, s. 776–790. doi: 10.1016/j.omtn.2019.07.011. Fulltekst i vitenarkiv
  • Idaszek, Joanna; Costantini, Marco; Karlsen, Tommy Aleksander; Jaroszewicz, Jakub; Colosi, Cristina & Testa, Stefano [Vis alle 16 forfattere av denne artikkelen] (2019). 3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head. Biofabrication. ISSN 1758-5082. 11(4), s. 1–15. doi: 10.1088/1758-5090/ab2622.
  • Karlsen, Tommy Aleksander; Aae, Tommy Frøseth & Brinchmann, Jan E. (2019). Robust profiling of microRNAs and isomiRs in human plasma exosomes across 46 individuals. Scientific Reports. ISSN 2045-2322. 9:19999, s. 1–9. doi: 10.1038/s41598-019-56593-7. Fulltekst i vitenarkiv
  • Kosik-Koziol, Alicja; Costantini, Marco; Mroz, Anna; Idaszek, Joanna; Heljak, Marcin & Jaroszewicz, Jakub [Vis alle 12 forfattere av denne artikkelen] (2019). 3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering. Biofabrication. ISSN 1758-5082. 11(3). doi: 10.1088/1758-5090/ab15cb.
  • Karlsen, Tommy Aleksander & Brinchmann, Jan E. (2019). Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulations . Experimental Cell Research. ISSN 0014-4827. 374(1), s. 122–127. doi: 10.1016/j.yexcr.2018.11.014. Fulltekst i vitenarkiv
  • Suliman, Salwa; Ali, Hassan Mohamed Abdel-Raouf; Karlsen, Tommy Aleksander; Amiaud, Jérôme; Mohamed Ahmed, Samih & Layrolle, Pierre [Vis alle 9 forfattere av denne artikkelen] (2019). Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells. Scientific Reports. ISSN 2045-2322. 9, s. 1–18. doi: 10.1038/s41598-019-52442-9. Fulltekst i vitenarkiv
  • Karlsen, Tommy Aleksander; Meenakshi Sundaram, Arvind Yegambaram & Brinchmann, Jan E. (2019). Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets. Cartilage. ISSN 1947-6035. doi: 10.1177/1947603519847746.
  • Rambøl, Mia Marie-Elisabeth; Hisdal, Jonny; Sundhagen, Jon Otto; Brinchmann, Jan E. & Rosales, Antonio (2018). Recellularization of decellularized venous grafts using peripheral blood: a critical evaluation. EBioMedicine. ISSN 2352-3964. 32, s. 215–222. doi: 10.1016/j.ebiom.2018.05.012. Fulltekst i vitenarkiv
  • Brinchmann, Bendik Christian; Skuland, Tonje Schwach; Rambøl, Mia Marie-Elisabeth; Szöke, Krisztina; Brinchmann, Jan E. & Gutleb, Arno C. [Vis alle 16 forfattere av denne artikkelen] (2018). Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s). Particle and Fibre Toxicology. ISSN 1743-8977. 15. doi: 10.1186/s12989-018-0257-1. Fulltekst i vitenarkiv
  • Behnan, Jinan; Stangeland, Biljana; Hosainey, Sayied Abdol Mohieb; Joel, Mrinal; Olsen, Thale Kristin & Micci, Francesca [Vis alle 9 forfattere av denne artikkelen] (2017). Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene. ISSN 0950-9232. 36(4), s. 570–584. doi: 10.1038/onc.2016.230.
  • Kosik-Kozioł, Alicja; Costantini, Marco; Bolek, Tomasz; Szöke, Krisztina; Barbetta, Andrea & Brinchmann, Jan E. [Vis alle 7 forfattere av denne artikkelen] (2017). PLA short sub-micron fiber reinforcement of 3D bioprinted alginate constructs for cartilage regeneration. Biofabrication. ISSN 1758-5082. 9:044105(4), s. 1–14. doi: 10.1088/1758-5090/aa90d7.
  • Szöke, Krisztina; Daňková, Jana; Buzgo, Matej; Amler, Evžen; Brinchmann, Jan E. & Østrup, Esben (2017). The effect of medium composition on deposition of collagen type 1 and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow. Process Biochemistry. ISSN 1359-5113. 59, s. 321–328. doi: 10.1016/j.procbio.2016.10.011.
  • Wollert, Kai C.; Meyer, Gerd P.; Müller-Ehmsen, Jochen; Tschöpe, Carsten; Bonarjee, Vernon V S & Larsen, Alf Inge [Vis alle 30 forfattere av denne artikkelen] (2017). Intracoronary autologous bone marrow cell transfer after myocardial infarction: The BOOST-2 randomised placebo-controlled clinical trial. European Heart Journal. ISSN 0195-668X. 38(39), s. 2936–2943. doi: 10.1093/eurheartj/ehx188.
  • Aae, Tommy Frøseth; Randsborg, Per-Henrik; Breen, Anne Berg; Visnes, Håvard; Vindfeld, Søren & Sivertsen, Einar [Vis alle 10 forfattere av denne artikkelen] (2016). Norwegian Cartilage Project - a study protocol for a double-blinded randomized controlled trail comparing arthroscopic microfracture with debridement in focal cartilage defects in the knee. BMC Musculoskeletal Disorders. ISSN 1471-2474. 17:292. doi: 10.1186/s12891-016-1156-y.
  • Behnan, Jinan; Stangeland, Biljana; Langella, Tiziana; Finocchiaro, Gaetano; Murrell, Wayne & Brinchmann, Jan E. (2016). Ultrasonic Surgical Aspirate is a Reliable Source for Culturing Glioblastoma Stem Cells. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep32788. Fulltekst i vitenarkiv
  • Costantini, Marco; Idaszek, Joanna; Szoke, Krisztina; Jaroszewicz, Jakub; Dentini, Mariella & Barbetta, Andrea [Vis alle 8 forfattere av denne artikkelen] (2016). 3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation. Biofabrication. ISSN 1758-5082. 8(3). doi: 10.1088/1758-5090/8/3/035002.
  • Randsborg, Per-Henrik; Brinchmann, Jan E.; Løken, Sverre Bertrand; Hanvold, Heidi Andreassen; Aae, Tommy Frøseth & Årøen, Asbjørn (2016). Focal cartilage defects in the knee -a randomized controlled trial comparing autologous chondrocyte implantation with arthroscopic debridement. BMC Musculoskeletal Disorders. ISSN 1471-2474. 17(1). doi: 10.1186/s12891-016-0969-z.
  • Karlsen, Tommy Aleksander; De Souza, Gustavo Antonio; Ødegård, Bjørn; Engebretsen, Lars & Brinchmann, Jan E. (2016). microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1beta-induced Osteoarthritis. Molecular Therapy - Nucleic Acids. ISSN 2162-2531. 5. doi: 10.1038/mtna.2016.64.
  • Szoke, Krisztina; Reinisch, Andreas; Østrup, Esben; Reinholt, Finn P. & Brinchmann, Jan E. (2016). Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue. Cytotherapy. ISSN 1465-3249. 18(2), s. 242–252. doi: 10.1016/j.jcyt.2015.10.009.
  • Foldager, Casper B.; Bendtsen, Michael; Berg, Lise C.; Brinchmann, Jan E.; Brittberg, Mats & Bunger, Cody [Vis alle 38 forfattere av denne artikkelen] (2016). Aarhus Regenerative Orthopaedics Symposium (AROS): Regeneration in the ageing population. Acta Orthopaedica. ISSN 1745-3674. 87, s. 1–5. doi: 10.1080/17453674.2017.1297918.
  • Lilledahl, Magnus Borstad; Magnus Østgård, Olderøy; Finnøy, Andreas; Olstad, Kristin & Brinchmann, Jan E. (2015). Second harmonic generation imaging in tissue engineering and cartilage pathologies. Progress in Biomedical Optics and Imaging. ISSN 1605-7422. 9329. doi: 10.1117/12.2081583.
  • Hart, Melanie L.; Izeta, Ander; Herrera-Imbroda, Bernardo; Amend, Bastian & Brinchmann, Jan E. (2015). Cell therapy for stress urinary incontinence. Tissue Engineering Part B: Reviews. ISSN 1937-3368. 21(4), s. 365–376. doi: 10.1089/ten.teb.2014.0627.
  • Klein, Gerd; Hart, Melanie L.; Brinchmann, Jan E.; Rolauffs, Bernd; Stenzl, Arnulf & Sievert, Karl-Dietrich [Vis alle 7 forfattere av denne artikkelen] (2015). Mesenchymal stromal cells for sphincter regeneration. Advanced Drug Delivery Reviews. ISSN 0169-409X. 82, s. 123–136. doi: 10.1016/j.addr.2014.10.026.
  • Pullisaar, Helen; Verket, Anders; Szoke, Krisztina; Tiainen, Hanna; Haugen, Håvard Jostein & Brinchmann, Jan E. [Vis alle 8 forfattere av denne artikkelen] (2015). Alginate hydrogel enriched with enamel matrix derivative to target osteogenic cell differentiation in TiO2 scaffolds. Journal of Tissue Engineering. ISSN 2041-7314. 6. doi: 10.1177/2041731415575870. Fulltekst i vitenarkiv
  • Magnus Østgård, Olderøy; Lilledahl, Magnus Borstad; Beckwith, Marianne; Melvik, Jan Egil; Reinholt, Finn P. & Sikorski, Pawel [Vis alle 7 forfattere av denne artikkelen] (2014). Biochemical and Structural Characterization of Neocartilage Formed by Mesenchymal Stem Cells in Alginate Hydrogels. PLOS ONE. ISSN 1932-6203. 9(3). doi: 10.1371/journal.pone.0091662. Fulltekst i vitenarkiv
  • Pullisaar, Helen; Reseland, Janne Elin; Haugen, Håvard Jostein; Brinchmann, Jan E. & Østrup, Esben (2014). Simvastatin coating of TiO2 scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 447(1), s. 139–144. doi: 10.1016/j.bbrc.2014.03.133.
  • Herlofsen, Sarah; Høiby, Torill; Cacchiarelli, Davide; Zhang, Xiaolan; Mikkelsen, Tarjei S. & Brinchmann, Jan E. (2014). Brief report: Importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells. Stem Cells. ISSN 1066-5099. 32(6), s. 1629–1635. doi: 10.1002/stem.1642.
  • Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn; Mikkelsen, Tarjei S. & Brinchmann, Jan E. (2014). microRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACAN. Stem Cells and Development. ISSN 1547-3287. 23(3), s. 290–304. doi: 10.1089/scd.2013.0209.
  • Jakobsen, Rune Bruhn; Østrup, Esben; Xiaolan, Zhang; Mikkelsen, Tarjei S. & Brinchmann, Jan E. (2014). Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLOS ONE. ISSN 1932-6203. 9(5). doi: 10.1371/journal.pone.0096615.
  • Karlsen, Tommy Aleksander & Brinchmann, Jan E. (2013). Liposome Delivery of MicroRNA-145 to Mesenchymal Stem Cells Leads to Immunological Off-target Effects Mediated by RIG-I. Molecular Therapy. ISSN 1525-0016. 21(6), s. 1169–1181. doi: 10.1038/mt.2013.55.
  • Herlofsen, Sarah; Bryne, Jan Christian; Høiby, Torill; Wang, Li; Issner, Robbyn & Zhang, XL [Vis alle 13 forfattere av denne artikkelen] (2013). Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells. BMC Genomics. ISSN 1471-2164. 14. doi: 10.1186/1471-2164-14-105.
  • Vik-Mo, Einar O.; Nyakas, Marta Sølvi; Mikkelsen, Birthe Viftrup; Moe, Morten Carsten; Due-Tønnessen, Paulina & Suso, Else Marit Inderberg [Vis alle 16 forfattere av denne artikkelen] (2013). Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma. Cancer Immunology and Immunotherapy. ISSN 0340-7004. 62(9), s. 1499–1509. doi: 10.1007/s00262-013-1453-3.
  • Rohban, Rokhsareh; Reinisch, Andreas; Etchart, Nathalie; Schallmoser, Katharina; Hofmann, Nicole A. & Szoke, Krisztina [Vis alle 10 forfattere av denne artikkelen] (2013). Identification of an Effective Early Signaling Signature during Neo-Vasculogenesis In Vivo by Ex Vivo Proteomic Profiling. PLOS ONE. ISSN 1932-6203. 8(6). doi: 10.1371/journal.pone.0066909.
  • Fernandes, Amilton Moreira; Herlofsen, Sarah; Karlsen, Tommy Aleksander; Kuchler, Axel Matthias; Fløisand, Yngvar & Brinchmann, Jan E. (2013). Similar Properties of Chondrocytes from Osteoarthritis Joints and Mesenchymal Stem Cells from Healthy Donors for Tissue Engineering of Articular Cartilage. PLOS ONE. ISSN 1932-6203. 8(5). doi: 10.1371/journal.pone.0062994.
  • Szoke, Krisztina; Beckstrøm, Karen Johanne & Brinchmann, Jan E. (2012). Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming. Stem Cell Research. ISSN 1873-5061. 9(2), s. 135–142. doi: 10.1016/j.scr.2012.05.006.
  • Szoke, Krisztina; Beckstrøm, Karen Johanne & Brinchmann, Jan E. (2012). Human adipose tissue as a source of cells with angiogenic potential. Cell Transplantation. ISSN 0963-6897. 21(1), s. 235–250. doi: 10.3727/096368911X580518.
  • Szoke, Krisztina & Brinchmann, Jan E. (2012). Concise review: therapeutic potential of adipose tissue-derived angiogenic cells. Stem Cells Translational Medicine. ISSN 2157-6564. 1(9), s. 658–667. doi: 10.5966/sctm.2012-0069.
  • Beitnes, Jan Otto; Øie, Erik; Shahdafar, Aboulghassem; Karlsen, Tommy Aleksander; Müller, Regine & Aakhus, Svend [Vis alle 8 forfattere av denne artikkelen] (2012). Intramyocardial Injections of Human Mesenchymal Stem Cells Following Acute Myocardial Infarction Modulate Scar Formation and Improve Left Ventricular Function. Cell Transplantation. ISSN 0963-6897. 21(8), s. 1697–1709. doi: 10.3727/096368911X627462.
  • Gordeladze, Jan Oxholm; Reseland, Janne Elin; Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn; Engebretsen, Lars & Lyngstadaas, Ståle Petter [Vis alle 9 forfattere av denne artikkelen] (2011). Bone and Cartilage from Stem Cells: Growth Optimalization and Stabilization of Cell Phenotypes. I Eberli, Daniel (Red.), Bone and Cartilage from Stem Cells: Growth Optimalization and Stabilization of Cell Phenotypes. IntechOpen. ISSN 978-953-307-663-8. s. 23–56. doi: 10.5772/19826.
  • Karlsen, Tommy Aleksander; Shahdafar, Aboulghassem & Brinchmann, Jan E. (2011). Human Primary Articular Chondrocytes, Chondroblasts-Like Cells, and Dedifferentiated Chondrocytes: Differences in Gene, MicroRNA, and Protein Expression and Phenotype. Tissue Engineering, Parts A, B, & C. ISSN 2152-4947. 17(2), s. 219–227. doi: 10.1089/ten.tec.2010.0200.
  • Duggal, Shivali & Brinchmann, Jan E. (2011). Importance of Serum Source for the In Vitro Replicative Senescence of Human Bone Marrow Derived Mesenchymal Stem Cells. Journal of Cellular Physiology. ISSN 0021-9541. 226(11), s. 2908–2915. doi: 10.1002/jcp.22637.
  • Beitnes, Jan Otto; Lunde, Ketil; Brinchmann, Jan E. & Aakhus, Svend (2011). Stem cells for cardiac repair in acute myocardial infarction. Expert Review of Cardiovascular Therapy. ISSN 1477-9072. 9(8), s. 1015–1025. doi: 10.1586/erc.11.108.
  • Herlofsen, Sarah; Kuechler, Axel Matthias; Melvik, Jan Egil & Brinchmann, Jan E. (2011). Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in Self-Gelling Alginate Discs Reveals Novel Chondrogenic Signature Gene Clusters. Tissue Engineering. ISSN 1076-3279. 17(7-8), s. 1003–1013. doi: 10.1089/ten.tea.2010.0499.
  • Karlsen, Tommy Aleksander; Mirtaheri, Peyman; Shahdafar, Aboulghassem; Fløisand, Yngvar & Brinchmann, Jan E. (2011). Effect of Three-Dimensional Culture and Incubator Gas Concentration on Phenotype and Differentiation Capability of Human Mesenchymal Stem Cells. Journal of Cellular Biochemistry. ISSN 0730-2312. 112(2), s. 684–693. doi: 10.1002/jcb.22978.
  • Jakobsen, Rune Bruhn; Shahdafar, Aboulghassem; Reinholt, Finn P. & Brinchmann, Jan E. (2010). Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 18(10), s. 1407–1416. doi: 10.1007/s00167-009-1017-4.
  • Duggal, Shivali; Frønsdal, Katrine; Szoke, Krisztina; Shahdafar, Aboulghassem; Melvik, Jan Egil & Brinchmann, Jan E. (2009). Phenotype and Gene Expression of Human Mesenchymal Stem Cells in Alginate Scaffolds. Tissue Engineering. ISSN 1076-3279. 15(7), s. 1763–1773. doi: 10.1089/ten.tea.2008.0306.
  • Beitnes, Jan Otto; Halvorsen, Bente ; Hopp, Einar; Lunde, Ketil; Solheim, Svein & Arnesen, Harald [Vis alle 9 forfattere av denne artikkelen] (2009). Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study. Heart. ISSN 1355-6037. 95(24), s. 1983–1989. doi: 10.1136/hrt.2009.178913.
  • Hildrestrand, Gunn Annette; Duggal, Shivali; Bjørås, Magnar; Luna, Luisa & Brinchmann, Jan E. (2009). Modulation of DNA glycosylase activities in mesenchymal stem cells. Experimental Cell Research. ISSN 0014-4827. 315(15), s. 2558–2567. doi: 10.1016/j.yexcr.2009.05.017.
  • Wester, T; Jorgensen, JJ; Stranden, E; Sandbaek, G; Tjonnfjord, G & Bay, D [Vis alle 9 forfattere av denne artikkelen] (2008). Treatment with autologous bone marrow mononuclear cells in patients with critical lower limb ischaemia. A pilot study. Scandinavian Journal of Surgery. ISSN 1457-4969. 97.
  • Wester, Torjus; Jørgensen, Jørgen J.; Stranden, Einar; Sandbæk, Gunnar; Tjønnfjord, G & Bay, Dag [Vis alle 9 forfattere av denne artikkelen] (2008). Treatment with autologous mononuclear cells in patients with critical lower limb ischaemia. A pilot study. Scandinavian Journal of Surgery. ISSN 1457-4969. 97, s. 56–62.
  • Wester, T; Jørgensen, Jørgen J.; Stranden, Einar; Tønnfjord, Geir E.; Bay, Dag & Sandbæk, Gunnar [Vis alle 9 forfattere av denne artikkelen] (2008). Treatment with autologous mononuclear cells in patients with critical lower limb ischemia. A pilot study. Scandinavian Journal of Surgery. ISSN 1457-4969. 97, s. 56–62.
  • Shahdafar, Aboulghassem; Løken, Sverre Bertrand; Dahl, John Arne; Tunheim, Siv Haugen; Collas, Philippe & Reinholt, Finn P. [Vis alle 8 forfattere av denne artikkelen] (2008). Persistence of Collagen Type II Synthesis and Secretion in Rapidly Proliferating Human Articular Chondrocytes In Vitro. Tissue Engineering. ISSN 1076-3279. 14(12), s. 1999–2007. doi: 10.1089/ten.tea.2007.0344.
  • Dahl, John Arne; Duggal, Shivali; Coulston, N; Millar, D; Melki, J & Shahdafar, Aboulghassem [Vis alle 8 forfattere av denne artikkelen] (2008). Genetic and epigenetic instability of human bone marrow mesenchymal stem cells expanded in autologous serum or fetal bovine serum. International Journal of Developmental Biology. ISSN 0214-6282. 52(8), s. 1033–1042. doi: 10.1387/ijdb.082663jd.
  • Løken, Sverre Bertrand; Jakobsen, Rune Bruhn; Årøen, Asbjørn; Heir, Stig; Shahdafar, Aboulghassem & Brinchmann, Jan E. [Vis alle 8 forfattere av denne artikkelen] (2008). Bone marrow mesenchymal stem cells in a hyaluronan scaffold for treatment of an osteochondral defect in a rabbit model. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 16, s. 896–903. doi: 10.1007/s00167-008-0566-2.
  • Brinchmann, Jan E. (2008). Expanding autologous multipotent mesenchymal bone marrow stromal cells. Journal of the Neurological Sciences. ISSN 0022-510X. 265. doi: 10.1016/j.jns.2007.05.006.
  • Boquest, Andrew Craig; Shahdafar, Aboulghassem; Brinchmann, Jan E. & Collas, Philippe (2006). Isolation of stromal stem cells from human adipose tissue. Methods in molecular biology. ISSN 1064-3745. s. 35–46.
  • Lunde, Ketil; Solheim, S; Aakhus, Svend; Arnesen, Harald; Abdelnoor, M & Egeland, T [Vis alle 20 forfattere av denne artikkelen] (2006). Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. New England Journal of Medicine. ISSN 0028-4793. 355(12), s. 1199–1209.
  • Kvale, Espen Østhagen; Dalgaard, Jakob; Lund-Johansen, Fridtjof; Rollag, Halvor; Farkas, Lorant & Midtvedt, Karsten [Vis alle 9 forfattere av denne artikkelen] (2006). CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell–stimulatory capability upon infection. Blood. ISSN 0006-4971. 107(5), s. 2022–2029. doi: 10.1182/blood-2005-05-2016.
  • Boquest, Andrew Craig; Shahdafar, A; Frønsdal, Katrine; Sigurjonsson, Olaur E.; Tunheim, S.H. & Collas, Philippe [Vis alle 7 forfattere av denne artikkelen] (2005). Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture. Molecular Biology of the Cell. ISSN 1059-1524. 16, s. 1131–1141.
  • Dalgaard, Jakob; Beckstrøm, Karen Johanne; Jahnsen, Frode Lars & Brinchmann, Jan E. (2005). Differential capability for phagocytosis of apoptotic and necrotic leukaemia cells by human peripheral blood dendritic cell subsets. Journal of Leukocyte Biology. ISSN 0741-5400. 77, s. 689–698.
  • Shahdafar, Aboulghassem; Frønsdal, Katrine; Haug, Terje; Reinholt, Finn P. & Brinchmann, Jan E. (2005). In vitro expansion of human mesenchymal stem cells: choice of serum is a determinant of cell proliferation, differentiation, gene expression and trascriptome stability. Stem Cells. ISSN 1066-5099. 23, s. 1357–1366.
  • Hedfors, Ida Aagård; Beckstrøm, Karen Johanne; Benati, Claudia; Bonini, Chiara & Brinchmann, Jan E. (2005). Retrovirus mediated gene transduction of human T-cell subsets. Cancer Immunology and Immunotherapy. ISSN 0340-7004. 54, s. 759–768. doi: 10.1007/s00262-004-0647-0.
  • Hedfors, Ida Aagård & Brinchmann, Jan E. (2004). Polyclonal T-cell activation protocol stimulates preferential expansion of EBV-specific T-cell clones in vitro. Cancer Immunology and Immunotherapy. ISSN 0340-7004. 58(5), s. 522–532.
  • Spurkland, Anne; Brinchmann, Jan E.; Markussen, Gunnar; Pedeutour, Florence; Munthe, Else & Lea, Tor [Vis alle 9 forfattere av denne artikkelen] (1998). Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites. Journal of Biological Chemistry. ISSN 0021-9258. doi: 10.1074/jbc.273.8.4539.

Se alle arbeider i Cristin

  • Aae, Tommy Frøseth; Karlsen, Tommy Aleksander; Bos-Haugen, Ida Kristin; Risberg, May Arna; Lian, Øystein Bjerkestrand & Brinchmann, Jan E. (2020). Evaluating plasma extracellular vesicle microRNAs as possible biomarkers for osteoarthritis. Osteoarthritis and Cartilage Open. ISSN 2665-9131. 1. doi: 10.1016/j.ocarto.2019.100018.
  • Årøen, Asbjørn; Kjennvold, Stian; Brinchmann, Jan E.; Randsborg, Per-Henrik; Reinholt, Finn P. & Engebretsen, Lars (2019). Bone marrow derived mesenchymal stem cells in a human clinical trial to repair articular cartilage defects of the knee .
  • Årøen, Asbjørn; Kjennvold, Stian; Brinchmann, Jan E.; Randsborg, Per-Henrik; Reinholt, Finn P. & Engebretsen, Lars (2018). Bone marrow derived mesenchymal stem cells in a human clinical trial to repair articular cartilage defects of the knee .
  • Karlsen, Tommy Aleksander; Jakobsen, Rune Bruhn & Brinchmann, Jan E. (2017). Early molecular events during in vitro chondrogenesisi. I Atkinson, Kerry (Red.), The biology and therapeutic Application of mesenchymal cells. Wiley-Blackwell. ISSN 978-1-118-90751-1. s. 167–190.
  • Pullisaar, Helen; Verket, Anders; Szoke, Krisztina; Tiainen, Hanna; Haugen, Håvard Jostein & Brinchmann, Jan E. [Vis alle 8 forfattere av denne artikkelen] (2014). Extracellular matrix coated ceramic scaffold enhance osteoblast differentiation.
  • Jakobsen, Rune Bruhn; Shahdafar, Aboulghassem; Reinholt, Finn P. & Brinchmann, Jan E. (2014). Erratum to Chondrogenesis in a hyaluronic acid scaffold: Comparison between chondrocytes and MSC from bone marrow and adipose tissue (Knee Surg Sports Traumatol Arthrosc, (2010), 18, (1407-1416), 10.1007/s00167-009-1017-4). Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 22(7), s. 1711–1714. doi: 10.1007/s00167-014-2938-0.
  • Olderøy, Magnus Østgård; Beckwith, Marianne; Rrinholt, F P; Lilledahl, Magnus Borstad; Sikorski, Pawel & Brinchmann, Jan E. (2013). Identification of functional structures in tissue engineered cartilage: from nm to macro scale. European Cells and Materials. ISSN 1473-2262. 26, s. 23–23.
  • Østrup, Esben; Tiainen, Hanna; Reseland, Janne Elin; Melvik, Jan Egil; Lyngstadaas, Ståle Petter & Brinchmann, Jan E. (2012). Improving conditions for MSC growth on porous TiO2 scaffolds. Journal of Tissue Engineering and Regenerative Medicine. ISSN 1932-6254. 6, s. 234–234.
  • Beitnes, Jan Otto; Øie, Erik; Shahdafar, Aboulghassem; Karlsen, Tommy Aleksander; Aakhus, Svend & Brinchmann, Jan E. (2010). Mesenchymal stem cells from skeletal muscle and adipose tissue improve LV function after myocardial infarction, but do not differentiate into cardiomyocytes. European Heart Journal. ISSN 0195-668X. 31, s. 397–397.
  • Beitnes, JO; Hopp, Einar; Lunde, Ketil; Smith, Hans-Jørgen; Solheim, Svein & Arnesen, Harald [Vis alle 9 forfattere av denne artikkelen] (2008). Long-term follow-up of left ventricular function after acute myocardial infarction treated with intracoronary injection of autologous bone marrow cells. The ASTAMI Study.
  • Wester, Torjus; Stranden, Einar; Jørgensen, Jørgen J.; Kroese, Andries Jan; Kazmi, SS & Sandbæk, Gunnar [Vis alle 10 forfattere av denne artikkelen] (2005). Autologe stamceller i behandlingen av pasienter med kritisk iskemi – en pilotstudie.
  • Fernandes, Amilton; Brinchmann, Jan E. & Engebretsen, Lars (2013). Tissue engineering of hyaline cartilage. A comparison between articular chondrocytes and mesenchymal stem cells. Universitetet i Oslo.
  • Duggal, Shivali & Brinchmann, Jan E. (2010). Human mesenchymal stem cells: Culture conditions, genomic and epigenetic stability and senescence. Unipub forlag. ISSN 978-82-8072-555-4.
  • Shahdafar, Aboulghassem & Brinchmann, Jan E. (2007). Human somatic cells in regenerative medicine : in vitro characterization of mesenchymal stem cells and chondrocytes. Unipub forlag. ISSN 978-82-8072-740-4.
  • Hedfors, Ida Aagård & Brinchmann, Jan E. (2007). Activation and gene transduction of human T cells. Unipub forlag. ISSN 978-82-8072-677-3.

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Publisert 13. apr. 2011 10:35 - Sist endret 15. jan. 2019 13:58