Hesso Farhan

Viktige Publikasjoner:

1) Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H*, Brodsky JL*, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 365, 53-60. (2019)

* Equal contribution

2) Centonze FG, Reiterer V, Nalbach K, Saito K, Pawlowski K, Behrends C, Farhan H. LTK is an ER-resident receptor tyrosine kinase that regulates secretion. J Cell Biol.  218, 2470-2480. (2019)

3) Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H. The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCF^FBXW7function. EMBO Journal 36(3):260-273. (2017)

4) Stadel D, Millarte V, Tillmann KD, Huber J, Tamin-Yecheskel B, Akutsu M, Demishtein A, Ben-Zeev B, Anikster Y, Perez F, Dötsch V, Elazar Z, Rogov V, Farhan H, Behrends C. (2015) TECPR2 cooperates with LC3C to regulate COPII dependent ER export. Mol Cell, 60(1):89-104 (2015).

5) Millarte V, Boncompain G, Tillmann K, Perez F, Sztul E, Farhan H. Phospholipase C gamma 1 regulates early secretory trafficking and cell migration via interaction with p115. Mol Biol Cell. 26(12):2263-78. (2015)

6) Tillmann KD, Reiterer V, Baschieri F, Hoffmann J, Millarte V, Hauser MA, Mazza A, Atias N, Sharan R, Legler DF, Weiss M, Farhan H. Regulation of Sec16 levels and dynamics links proliferation and secretion. J Cell Sci. 128(4):670-682. (2015)

7) Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nature Commun. 5:4839. (2014)

8) Reiterer V, Fey D, Kolch W, Kholodenko B, Farhan H.Pseudophosphatase STYX modulates cell fate decisions and cell migration by spatio-temporal regulation of ERK1/2. Proc Natl Acad Sci. 110(31):E2934-2943. (2013)

9) Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady N, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D and Ivan Dikic I. Phosphorylation of the Autophagy Receptor Optineurin restricts Salmonella Growth. Science 333:228-233. (2011)

10) Farhan H, Wendeler MW, Mitrovic S, Fava E, Silberberg Y, Sharan R, Zerial M, Hauri HP. MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening. J Cell Biol 189:997-1011. (2010)

11) Farhan H, Weiss M, Tani K, Kaufman RJ, Hauri HP. Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load. EMBO J  27:2043-2054. (2008)

• Besse, Lenka; Besse, Andrej; Stolze, Sara C.; Sobh, Amin; Zaal, Esther A & Ham, Alwin J.Van Der [Vis alle 25 forfattere av denne artikkelen] (2021). Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple myeloma. Cancer Research. ISSN 0008-5472. 81(17), s. 4581–4593. doi: 10.1158/0008-5472.CAN-20-3323. Fulltekst i vitenarkiv
• Ghannoum, Salim; Antos, Kamil; Netto, Waldir Leoncio; Gomes, Cecil; Köhn-Luque, Alvaro & Farhan, Hesso (2021). CellMAPtracer: A User-Friendly Tracking Tool for Long-Term Migratory and Proliferating Cells Associated with FUCCI Systems. Cells. ISSN 2073-4409. 10(2), s. 1–18. doi: 10.3390/cells10020469. Fulltekst i vitenarkiv
• Ghannoum, Salim; Netto, Waldir Leoncio; Fantini, Damiano; Ragan-Kelley, Benjamin; Parizadeh, Seyedamirabbas & Jonasson, Emma [Vis alle 9 forfattere av denne artikkelen] (2021). DIscBIO: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics. International Journal of Molecular Sciences. ISSN 1661-6596. 22(3). doi: 10.3390/ijms22031399. Fulltekst i vitenarkiv
• Reiterer, Veronika; Pawlowski, Krzysztof; Desrochers, Guillaume; Pause, Arnim; Sharpe, Hayley J. & Farhan, Hesso (2020). The dead phosphatases society: a review of the emerging roles of pseudophosphatases. The FEBS Journal. ISSN 1742-464X. 287(19), s. 4198–4220. doi: 10.1111/febs.15431. Fulltekst i vitenarkiv
• Eck, Franziska; Phuyal, Santosh; Smith, Matthew D.; Kaulich, Manuel; Wilkinson, Simon & Farhan, Hesso [Vis alle 7 forfattere av denne artikkelen] (2020). ACSL3 is a novel GABARAPL2 interactor that links ufmylation and lipid droplet biogenesis. Journal of Cell Science. ISSN 0021-9533. 133(18), s. 1–16. doi: 10.1242/jcs.243477. Fulltekst i vitenarkiv
• Farhan, Hesso (2020). Rendezvous of Retro-2 at the ER. Nature Chemical Biology. ISSN 1552-4450. 16(3), s. 229–230. doi: 10.1038/s41589-020-0475-3. Fulltekst i vitenarkiv
• Gilljam, Karin Margaretha; Holm, Kristine Lillebø; Zahoor, Muhammad; Centonze, Federica Grazia; Farhan, Hesso & Blomhoff, Heidi Kiil (2020). Differential Effects of Reactive Oxygen Species on IgG versus IgM Levels in TLR-Stimulated B Cells. Journal of Immunology. ISSN 0022-1767. 204(8), s. 2133–2142. doi: 10.4049/jimmunol.1901131.
• Farhan, Hesso (2020). Tyrosine kinase signaling in and on the endoplasmic reticulum. Biochemical Society Transactions. ISSN 0300-5127. 48(1), s. 199–205. doi: 10.1042/BST20190543. Fulltekst i vitenarkiv
• Plissonnier, Marie-Laure; Cottarel, Jessica; Piver, Eric; Kullolli, Majlinda; Centonze, Federica Grazia & Pitteri, Sharon [Vis alle 10 forfattere av denne artikkelen] (2019). LARP1 binding to hepatitis C virus particles is correlated with intracellular retention of viral infectivity. Virus Research. ISSN 0168-1702. 271(197679). doi: 10.1016/j.virusres.2019.197679. Fulltekst i vitenarkiv
• Phuyal, Santosh & Farhan, Hesso (2019). Multifaceted Rho GTPase Signaling at the Endomembranes. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 7(127). doi: 10.3389/fcell.2019.00127. Fulltekst i vitenarkiv
• Centonze, Federica Grazia; Reiterer, Veronika; Nalbach, Karsten; Saito, Kota; Pawlowski, Krzysztof & Behrends, Christian [Vis alle 7 forfattere av denne artikkelen] (2019). LTK is an ER-resident receptor tyrosine kinase that regulates secretion . Journal of Cell Biology. ISSN 0021-9525. 218(8), s. 2470–2480. doi: 10.1083/jcb.201903068. Fulltekst i vitenarkiv
• Centonze, Federica Grazia & Farhan, Hesso (2019). Crosstalk of endoplasmic reticulum exit sites and cellular signaling. FEBS Letters. ISSN 0014-5793. s. 1–9. doi: 10.1002/1873-3468.13569. Fulltekst i vitenarkiv
• Cui, Yixian; Parashar, Smriti; Zahoor, Muhammad; Needham, Patrick; Mari, Muriel & Zhu, Ming [Vis alle 12 forfattere av denne artikkelen] (2019). A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. ISSN 0036-8075. 365(6448), s. 53–60. doi: 10.1126/science.aau9263. Fulltekst i vitenarkiv
• Saponara, Enrica; Visentin, Michele; Baschieri, Francesco; Seleznik, Gitta; Martinelli, Paola & Esposito, Irene [Vis alle 16 forfattere av denne artikkelen] (2018). Serotonin uptake is required for Rac1 activation in Kras-induced acinar-to-ductal metaplasia in the pancreas. Journal of Pathology. ISSN 0022-3417. 246(3), s. 352–365. doi: 10.1002/path.5147.
• Farhan, Hesso; Legler, D; Uetz-von Allmen, Edith & Rippl, Alexandra V (2018). A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking. Journal of Leukocyte Biology. ISSN 0741-5400. doi: 10.1002/JLB.2VMA1217-429R.
• Farhan, Hesso & Zahoor, Muhammad (2018). Crosstalk of Autophagy and the Secretory Pathway and Its Role in Diseases. International Review of Cell and Molecular Biology. ISSN 1937-6448. 337, s. 153–184. doi: 10.1016/bs.ircmb.2017.12.004. Fulltekst i vitenarkiv
• Murphy, James M.; Farhan, Hesso & Eyers, Patrick A. (2017). Bio-Zombie: The rise of pseudoenzymes in biology. Biochemical Society Transactions. ISSN 0300-5127. 45(2), s. 537–544. doi: 10.1042/BST20160400.
• Farhan, Hesso; Kundu, Mondira & Ferro-Novick, Susan (2017). The link between autophagy and secretion: A story of multitasking proteins. Molecular Biology of the Cell. ISSN 1059-1524. 28(9), s. 1161–1164. doi: 10.1091/mbc.E16-11-0762. Fulltekst i vitenarkiv
• Reiterer, Veronika; Pawłowski, Krzysztof & Farhan, Hesso (2017). STYX: A versatile pseudophosphatase. Biochemical Society Transactions. ISSN 0300-5127. 45(2), s. 449–456. doi: 10.1042/BST20160279.
• Reiterer-Farhan, Veronika; Figueras‐Puig, Cristina; Le Guerroue,, Francois; Confalonieri, Stefano; Vecchi, Manuela & Jalapothu, Dasaradha [Vis alle 11 forfattere av denne artikkelen] (2017). The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCFFBXW7 function. EMBO Journal. ISSN 0261-4189. 36(3), s. 260–273. doi: 10.15252/embj.201694795.
• Farhan, Hesso (2016). Regulation of EGFR surface levels by COP II-dependent trafficking. Journal of Cell Biology. ISSN 0021-9525. 215(4), s. 441–443. doi: 10.1083/jcb.201611014.

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• Phuyal, Santosh & Farhan, Hesso (2021). Want to leave the ER? We offer vesicles, tubules, and tunnels. Journal of Cell Biology. ISSN 0021-9525. 220(6). doi: 10.1083/jcb.202104062.
• Chevet, Eric; Matteis, Antonella De; Eskelinen, Eeva-Liisa & Farhan, Hesso (2021). Traffic: A new board, a new journey. Traffic : the International Journal of Intracellular Transport. ISSN 1398-9219. 22(1-2), s. 4–5. doi: 10.1111/tra.12778.

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