Hesso Farhan

Professor - Cellesignalering
Bilde av Hesso Farhan
English version of this page
Telefon +47 22851217
Rom 1238
Brukernavn
Besøksadresse Sognsvannsveien 9 Domus Medica 0372 OSLO
Postadresse Postboks 1112 Blindern 0372 Oslo
Emneord: Cellebiologi, Celle signalering, Kreft, metastase, Membrantransport, Proteostase

Publikasjoner

Viktige Publikasjoner:

 

1) Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H*, Brodsky JL*, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 365, 53-60. (2019)

* Equal contribution

 

2) Centonze FG, Reiterer V, Nalbach K, Saito K, Pawlowski K, Behrends C, Farhan H. LTK is an ER-resident receptor tyrosine kinase that regulates secretion. J Cell Biol.  218, 2470-2480. (2019)

 

3) Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H. The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7function. EMBO Journal 36(3):260-273. (2017)

 

4) Stadel D, Millarte V, Tillmann KD, Huber J, Tamin-Yecheskel B, Akutsu M, Demishtein A, Ben-Zeev B, Anikster Y, Perez F, Dötsch V, Elazar Z, Rogov V, Farhan H, Behrends C. (2015) TECPR2 cooperates with LC3C to regulate COPII dependent ER export. Mol Cell, 60(1):89-104 (2015).

 

5) Millarte V, Boncompain G, Tillmann K, Perez F, Sztul E, Farhan H. Phospholipase C gamma 1 regulates early secretory trafficking and cell migration via interaction with p115. Mol Biol Cell. 26(12):2263-78. (2015)

 

6) Tillmann KD, Reiterer V, Baschieri F, Hoffmann J, Millarte V, Hauser MA, Mazza A, Atias N, Sharan R, Legler DF, Weiss M, Farhan H. Regulation of Sec16 levels and dynamics links proliferation and secretion. J Cell Sci. 128(4):670-682. (2015)

 

7) Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nature Commun. 5:4839. (2014)

 

8) Reiterer V, Fey D, Kolch W, Kholodenko B, Farhan H.Pseudophosphatase STYX modulates cell fate decisions and cell migration by spatio-temporal regulation of ERK1/2. Proc Natl Acad Sci. 110(31):E2934-2943. (2013)

 

9) Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady N, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D and Ivan Dikic I. Phosphorylation of the Autophagy Receptor Optineurin restricts Salmonella Growth. Science 333:228-233. (2011)

 

10) Farhan H, Wendeler MW, Mitrovic S, Fava E, Silberberg Y, Sharan R, Zerial M, Hauri HP. MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening. J Cell Biol 189:997-1011. (2010)

 

11) Farhan H, Weiss M, Tani K, Kaufman RJ, Hauri HP. Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load. EMBO J  27:2043-2054. (2008)

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Publisert 23. aug. 2016 15:00 - Sist endret 19. feb. 2020 19:41