Anders Hartmann

• Jørgensen, Hanne Skou; Eide, Ivar Anders; Jenssen, Trond; Åsberg, Anders; Bollerslev, Jens & Godang, Kristin [Show all 9 contributors for this article] (2021). Marine n-3 polyunsaturated fatty acids and bone mineral density in kidney transplant recipients: A randomized, placebo-controlled trial. Nutrients. ISSN 2072-6643. 13(7), p. 1–10. doi: 10.3390/nu13072361. Full text in Research Archive
• Haugen, Anders Johan Smedman; Hallan, Stein; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege & Birkeland, Kåre I. [Show all 11 contributors for this article] (2020). Increased long-term risk for hypertension in kidney donors – a retrospective cohort study. Transplant International. ISSN 0934-0874. 33(5), p. 536–543. doi: 10.1111/tri.13576.
• Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders & Hartmann, Anders [Show all 8 contributors for this article] (2020). Endothelial function after pancreas transplantation - A single-center observational study. Clinical Transplantation. ISSN 0902-0063. 34:e13815(3), p. 1–7. doi: 10.1111/ctr.13815. Full text in Research Archive
• Pihlstrøm, Hege; Ueland, Thor; Michelsen, Annika; Aukrust, Pål; Gatti, Francesca & Hammarström, Clara Louise [Show all 15 contributors for this article] (2020). Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients. PLOS ONE. ISSN 1932-6203. 15:e0243759(12), p. 1–14. doi: 10.1371/journal.pone.0243759. Full text in Research Archive
• Åsberg, Anders; Bjerre, Anna Kristina; Almaas, Runar; Luis-Lima, Sergio; Robertsen, Ida & Salvador, Cathrin Lytomt [Show all 10 contributors for this article] (2019). Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance. Kidney International Reports. ISSN 2468-0249. 5(2), p. 189–198. doi: 10.1016/j.ekir.2019.11.012. Full text in Research Archive
• Jenssen, Trond Geir & Hartmann, Anders (2019). Post-transplant diabetes mellitus in patients with solid organ transplants. Nature Reviews Endocrinology. ISSN 1759-5029. 15(3), p. 172–188. doi: 10.1038/s41574-018-0137-7. Full text in Research Archive
• Ussif, Mohammed Al-Amin; Åsberg, Anders; Strøm Halden, Thea Anine; Nordheim, Espen; Hartmann, Anders & Jenssen, Trond Geir (2019). Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation. BMC Nephrology. ISSN 1471-2369. 20:12, p. 1–6. doi: 10.1186/s12882-018-1171-3. Full text in Research Archive
• Eide, Ivar Anders; Reinholt, Finn P.; Jenssen, Trond Geir; Hartmann, Anders; Schmidt, Erik B. & Åsberg, Anders [Show all 9 contributors for this article] (2019). Effects of marine n-3 fatty acid supplementation in renal transplantation: A randomized controlled trial. American Journal of Transplantation. ISSN 1600-6135. 19, p. 790–800. doi: 10.1111/ajt.15080.
• Strøm Halden, Thea Anine; Kvitne, Kine Eide; Midtvedt, Karsten; Rajakumar, Laavanyaah; Robertsen, Ida & Brox, Jan [Show all 10 contributors for this article] (2019). Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus. Diabetes Care. ISSN 0149-5992. 42(6), p. 1067–1074. doi: 10.2337/dc19-0093. Full text in Research Archive
• Thorsen, Inga Strand; Bleskestad, Inger Hjørdis; Åsberg, Anders; Hartmann, Anders; Skadberg, Øyvind & Brede, Cato [Show all 10 contributors for this article] (2019). Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study. Clinical Transplantation. ISSN 0902-0063. 33:e13517(5), p. 1–12. doi: 10.1111/ctr.13517. Full text in Research Archive
• Gustavsen, Marte Theie; Midtvedt, Karsten; Lønning, Kjersti; Jacobsen, Thea Johnsen; Reisæter, Anna Varberg & De Geest, Sabina [Show all 9 contributors for this article] (2019). Evaluation of tools for annual capture of adherence to immunosuppressive medications after renal transplantation – a single‐centre open prospective trial. Transplant International. ISSN 0934-0874. 32(6), p. 614–625. doi: 10.1111/tri.13412.
• Haugen, Anders; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege; Birkeland, Kåre I. & Reisæter, Anna Varberg [Show all 10 contributors for this article] (2019). Long-term risk for kidney donors with hypertension at donation ? a retrospective cohort study. Transplant International. ISSN 0934-0874. doi: 10.1111/tri.13443. Full text in Research Archive
• Egeland, Erlend Johannessen; Reisæter, Anna Varberg; Robertsen, Ida; Midtvedt, Karsten; Strøm, Erik Heyerdahl & Holdaas, Hallvard [Show all 8 contributors for this article] (2018). High tacrolimus clearance ? a risk factor for development of interstitial fibrosis and tubular atrophy in the transplanted kidney: a retrospective single-center cohort study. Transplant International. ISSN 0934-0874. 32(3), p. 257–269. doi: 10.1111/tri.13356.
• Chandra, Anupam; Svensson, My Hanna Sofia; Åsberg, Anders; Schmidt, Erik Berg; Bjerve, Kristian S & Jenssen, Trond Geir [Show all 9 contributors for this article] (2018). Trans-fatty acids and survival in renal transplantation. Journal of renal nutrition. ISSN 1051-2276. 29(3), p. 169–180. doi: 10.1053/j.jrn.2018.08.003. Full text in Research Archive
• Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg & Chandra, Anupam [Show all 10 contributors for this article] (2018). Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation. Journal of renal nutrition. ISSN 1051-2276. 28(5), p. 333–339. doi: 10.1053/j.jrn.2018.02.008. Full text in Research Archive
• Nordheim, Espen; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune & Jenssen, Trond Geir (2018). Preserved insulin secretion and kidney function in recipients with functional pancreas grafts 1 year after transplantation: a single-center prospective observational study. European Journal of Endocrinology (EJE). ISSN 0804-4643. 179(4), p. 251–259. doi: 10.1530/EJE-18-0360.
• Nordheim, Espen; Horneland, Rune; Aandahl, Einar Martin; Grzyb, Krzysztof; Aabakken, Lars & Paulsen, Vemund [Show all 9 contributors for this article] (2018). Pancreas transplant rejection episodes are not revealed by biopsies of the donor duodenum in a prospective study with paired biopsies. American Journal of Transplantation. ISSN 1600-6135. 18(5), p. 1256–1261. doi: 10.1111/ajt.14658.
• Ussif, Mohammed Al-Amin; Pihlstrøm, Hege; Pasch, Andreas; Holdaas, Hallvard; Hartmann, Anders & Smerud, Knut Terje [Show all 7 contributors for this article] (2018). Paricalcitol supplementation during the first year after kidney transplantation does not affect calcification propensity score. BMC Nephrology. ISSN 1471-2369. 19(1). doi: 10.1186/s12882-018-1000-8. Full text in Research Archive
• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Godang, Kristin; Hartmann, Anders & Åsberg, Anders (2018). Arterial stiffness is associated with visceral fat mass in kidney transplanted patients—A nationwide cohort study. Clinical Transplantation. ISSN 0902-0063. 32(8). doi: 10.1111/ctr.13341.
• Heldal, Torbjørn Fossum; Ueland, Thor; Jenssen, Trond Geir; Hartmann, Anders; Reisæter, Anna Varberg & Aukrust, Pål [Show all 8 contributors for this article] (2018). Inflammatory and related biomarkers are associated with post-transplant diabetes mellitus in kidney recipients: a retrospective study. Transplant International. ISSN 0934-0874. 31(5), p. 510–519. doi: 10.1111/tri.13116.
• Lønning, Kjersti; Heldal, Kristian; Bernklev, Tomm; Brunborg, Cathrine; Andersen, Marit Helen & Lippe, Nanna von der [Show all 10 contributors for this article] (2018). Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation. Transplantation direct. ISSN 2373-8731. doi: 10.1097/TXD.0000000000000770. Full text in Research Archive
• Eide, Ivar Anders; Dörje, Christina; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Hammarström, Clara Louise & Scott, Helge [Show all 13 contributors for this article] (2018). Development of Kidney Transplant Fibrosis Is Inversely Associated With Plasma Marine Fatty Acid Level. Journal of renal nutrition. ISSN 1051-2276. 28(2), p. 118–124. doi: 10.1053/j.jrn.2017.09.001.
• Heldal, Kristian; Midtvedt, Karsten; Hartmann, Anders; Reisæter, Anna Varberg; Heldal, Torbjørn Fossum & Bergan, Stein [Show all 8 contributors for this article] (2018). Estimated glomerular filtration rate in stable older kidney transplant recipients-are present algorithms valid? A national cross-sectional cohort study. Transplant International. ISSN 0934-0874. 31(6), p. 629–638. doi: 10.1111/tri.13137. Full text in Research Archive
• Lindahl, Jørn Petter Hanto; Horneland, Rune; Nordheim, Espen; Hartmann, Anders; Aandahl, Einar Martin & Grzyb, Krzysztof [Show all 10 contributors for this article] (2018). Outcomes in Pancreas Transplantation With Exocrine Drainage Through a Duodenoduodenostomy Versus Duodenojejunostomy. American Journal of Transplantation. ISSN 1600-6135. 18(1), p. 154–162. doi: 10.1111/ajt.14420. Full text in Research Archive
• Lønning, Kjersti; Midtvedt, Karsten; Bernklev, Tomm; Brunborg, Cathrine; Andersen, Marit Helen & Lippe, Nanna von der [Show all 10 contributors for this article] (2018). Changes in health related quality of life in older candidates waiting for kidney transplantation. Nephrology. ISSN 1320-5358. 23(10), p. 948–956. doi: 10.1111/nep.13117.
• Smedbråten, Julia; Sagedal, Solbjørg; Åsberg, Anders; Hartmann, Anders; Rollag, Halvor & Mjøen, Geir [Show all 10 contributors for this article] (2017). Collectin liver 1 and collectin kidney 1 of the lectin complement pathway are associated with mortality after kidney transplantation. American Journal of Transplantation. ISSN 1600-6135. 17(1), p. 265–271. doi: 10.1111/ajt.13933.
• Dahle, Dag Olav; Grotmol, Tom; Leivestad, Torbjørn; Hartmann, Anders; Midtvedt, Karsten & Reisæter, Anna Varberg [Show all 10 contributors for this article] (2017). Association Between Pretransplant Cancer and Survival in Kidney Transplant Recipients. Transplantation. ISSN 0041-1337. 101(10), p. 2599–2605. doi: 10.1097/TP.0000000000001659.
• Salvador, Cathrin Lytomt; Hartmann, Anders; Åsberg, Anders; Bergan, Stein; Rowe, Alexander D. & Mørkrid, Lars (2017). Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population. Transplantation direct. ISSN 2373-8731. 3(12). doi: 10.1097/TXD.0000000000000742. Full text in Research Archive
• Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik & Hartmann, Anders [Show all 12 contributors for this article] (2017). Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition. ISSN 1051-2276. 27(3), p. 161–168. doi: 10.1053/j.jrn.2016.09.008. Show summary

  OBJECTIVE: Marine n-3 polyunsaturated fatty acids (PUFAs) exert potential anti-inflammatory effects and might improve long-term outcomes after renal transplantation. We assessed associations between plasma phospholipid levels of marine n-3 PUFAs and plasma inflammatory biomarkers 10 weeks after renal transplantation. DESIGN: Cross-sectional single-center study. SUBJECTS: A study population of 861 renal transplant recipients transplanted at Oslo University Hospital between 2007 and 2011. METHODS AND MAIN OUTCOME MEASURE: Plasma phospholipid fatty acids were determined by gas chromatography. Marine n-3 PUFA levels were defined as the sum of eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid levels in weight percentage of total plasma phospholipid fatty acids. Plasma inflammatory biomarkers were measured by enzyme immunoassays. We used multivariable linear regression analysis to assess associations between levels of marine n-3 PUFAs and inflammatory biomarkers in plasma. RESULTS: Plasma marine n-3 PUFA levels were inversely associated with plasma levels of proinflammatory biomarkers soluble tumor necrosis factor receptor 1 (standardized regression coefficient -0.11, P < .001) and interleukin-6 (standardized regression coefficient -0.09, P = .01). In contrast, there was no association between plasma levels of marine n-3 PUFAs and the anti-inflammatory mediator interleukin-10. CONCLUSIONS: In this renal transplant cohort, inverse associations between plasma levels of marine n-3 PUFAs and markers of inflammation were demonstrated.

• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin & Hartmann, Anders (2017). Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation. Clinical Transplantation. ISSN 0902-0063. 31:e12869(1), p. 1–9. doi: 10.1111/ctr.12869. Full text in Research Archive
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Dahle, Dag Olav; Åsberg, Anders & Jenssen, Trond Geir (2017). Associations Between Posttransplantation Diabetes Mellitus and Renal Graft Survival. Transplantation. ISSN 0041-1337. 101(6), p. 1282–1289. doi: 10.1097/TP.0000000000001259. Show summary

  BACKGROUND: Previous reports indicate that posttransplantation diabetes mellitus (PTDM) is associated with overall renal graft loss, but not death-censored graft loss. METHODS: In this single-center retrospective cohort study of 2749 adult Norwegian renal transplant recipients, transplanted between 1999 and 2011, we estimated overall and death-censored renal graft loss hazard ratios in patients diagnosed with PTDM, impaired glucose tolerance and diabetes before transplantation, using multivariable Cox proportional hazard regression analysis. RESULTS: A total of 893 renal grafts were lost during the study period, either due to recipient death (n = 540) or death-censored graft loss (n = 353). When the observational time started at time of transplantation, diabetes before transplantation was associated with both overall and death-censored graft loss. Pretransplantation diabetes was also associated with a steeper decline in renal graft function, a higher risk of acute rejections and more renal grafts lost due to acute rejection. In patients with a functional renal graft 1 year after transplantation, PTDM was associated with overall graft loss (hazard ratio, 1.46; 95% confidence interval, 1.13-1.88; P < 0.001), but not death-censored graft loss (hazard ratio, 1.25; 95% confidence interval, 0.80-1.96; P = 0.33). We found no significant associations between PTDM and change in renal function during the first 5 years or acute rejection risk during the first year after renal transplantation. Impaired glucose tolerance was not associated with either overall or death-censored graft loss. CONCLUSIONS: The present study confirms previous findings of an increased risk of overall but not death-censored renal graft loss in renal transplant recipients with PTDM. Longstanding diabetes might increase the risk of acute rejections.

• Lindahl, Jørn Petter Hanto; Massey, Richard; Hartmann, Anders; Aakhus, Svend; Endresen, Knut & Günther, Anne [Show all 12 contributors for this article] (2017). Cardiac Assessment of Patients With Type 1 Diabetes Median 10 Years After Successful Simultaneous Pancreas and Kidney Transplantation Compared With Living Donor Kidney Transplantation. Transplantation. ISSN 0041-1337. 101(6), p. 1261–1267. doi: 10.1097/TP.0000000000001274.
• Pihlstrøm, Hege; Gatti, Francesca; Hammarström, Clara Louise; Eide, Ivar Anders; Kasprzycka, Monika & Wang, Junbai [Show all 13 contributors for this article] (2017). Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study. Transplant International. ISSN 0934-0874. 30(8), p. 827–840. doi: 10.1111/tri.12973.
• Dupont, Laust; Eide, Ivar Anders; Hartmann, Anders; Christensen, Jeppe Hagstrup; Åsberg, Anders & Jenssen, Trond Geir [Show all 8 contributors for this article] (2017). Haptoglobin 2-2 Genotype, Patient, and Graft Survival in Renal Transplant Recipients. Progress in transplantation. ISSN 1526-9248. 27(4), p. 386–391. doi: 10.1177/1526924817732020. Full text in Research Archive
• Heldal, Kristian; Hartmann, Anders; Lønning, Kjersti; Leivestad, Torbjørn; Reisæter, Anna Varberg & Line, Pål Dag [Show all 8 contributors for this article] (2017). Should patients older than 65 years be offered a second kidney transplant? BMC Nephrology. ISSN 1471-2369. 18(13). doi: 10.1186/s12882-016-0426-0. Full text in Research Archive
• Smerud, Knut Terje; Åsberg, Anders; Kile, Håkon; Pasch, Andreas; Dahle, Dag Olav & Bollerslev, Jens [Show all 8 contributors for this article] (2017). A rapid and sustained improvement of calcification propensity score (serum T50) after successful kidney transplantation: Reanalysis of a randomized controlled trial of ibandronate. Clinical Transplantation. ISSN 0902-0063. 31(12). doi: 10.1111/ctr.13131. Full text in Research Archive
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Show all 12 contributors for this article] (2017). High tacrolimus clearance is a risk factor for acute rejection in the early phase after renal transplantation. Transplantation. ISSN 0041-1337. 101(8), p. e273–e279. doi: 10.1097/TP.0000000000001796. Full text in Research Archive
• Rose, J; Emery, Vincent C; Kumar, Deepali; Åsberg, Anders; Hartmann, Anders & Jardine, Alan G. [Show all 9 contributors for this article] (2017). Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection. PLoS Pathogens. ISSN 1553-7366. 13(4). doi: 10.1371/journal.ppat.1006299. Full text in Research Archive
• Meyer, Käthe Birgitte; Hartmann, Anders; Mjøen, Geir & Andersen, Marit Helen (2017). Relationships between clinical, self-reported, and donation specific outcomes: a prospective follow-up study 10 years after kidney donation. Annals of Transplantation. ISSN 1425-9524. 22, p. 148–155. doi: 10.12659/AOT.902330. Full text in Research Archive
• Jenssen, Trond Geir; Hartmann, Anders & Birkeland, Kåre I. (2017). Long-term diabetes complications after pancreas transplantation. Current Opinion in Organ Transplantation. ISSN 1087-2418. 22(4), p. 382–388. doi: 10.1097/MOT.0000000000000436.
• SMEDBRÅTEN, Julia; Mjøen, Geir; Hartmann, Anders; Åsberg, Anders; Rollag, Halvor & Mollnes, Tom Eirik [Show all 10 contributors for this article] (2016). Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients. BMC Nephrology. ISSN 1471-2369. 17(1). doi: 10.1186/s12882-016-0373-9. Full text in Research Archive Show summary

  Background Higher incidence of malignancy and infectious diseases in kidney transplant recipients is related to immunosuppressive treatment after transplantation and the recipient’s native immune system. The complement system is an essential component of the innate immunity. The aim of the present study was to investigate the association of effector molecules of the lectin complement pathway with graft and patient survival after kidney transplantation. Methods Two mannan-binding lectin (MBL) associated proteases, MASP-2 and MASP-3 (activators of the lectin pathway) and two MBL-associated proteins, MAp44 and MAp19 (inhibitors of the lectin pathway) were measured at the time of transplantation in 382 patients (≥17 years old) transplanted in 2000–2001. The cohort was followed until December 31, 2014. Data on patient and graft survival were obtained from the Norwegian Renal Registry. Cox proportional hazard regression models were performed for survival analyses. Results Low MAp44 level (1st versus 2–4 quartile) was significantly associated with overall mortality; HR 1.52, 95 % CI 1.08–2.14, p = 0.017. In the sub analyses in groups below and above median age (51.7 years), low MAp44 as a predictor of overall mortality was statistically significant only in recipients of ≤51.7 years; HR 2.57, 95 % CI 1.42–4.66, p = 0.002. Furthermore, low MAp44 was associated with mortality due to infectious diseases; HR 2.22, 95 % CI 1.11–4.41, p = 0.023. There was no association between MASP-2, MASP-3 or MAp19 levels and patient mortality. No association between any measured biomarkers and death censored graft loss was found. Conclusions Low MAp44 level at the time of transplantation was associated with increased overall mortality in kidney recipients of median age of 51.7 years or below and with mortality due to infectious diseases in the whole patient cohort after nearly 14-years of follow up after transplantation. No associations between other effector molecules; MASP-2, MASP-3 or MAp19 and recipient mortality were found, as well as no association of any biomarker with death censored graft loss. Keywords Kidney transplantation – Complement – Recipient survival

• Størset, Elisabet; Åsberg, Anders; Hartmann, Anders; Reisæter, Anna Varberg; Holdaas, Hallvard & Skauby, Morten Heier [Show all 8 contributors for this article] (2016). Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience. Nephrology. ISSN 1320-5358. 21(10), p. 821–827. doi: 10.1111/nep.12738.
• Lønning, Kjersti; Midtvedt, Karsten; Leivestad, Torbjørn; Reisæter, Anna Varberg; Line, Pål Dag & Hartmann, Anders [Show all 7 contributors for this article] (2016). Are Octogenarians with End-Stage Renal Disease Candidates for Renal Transplantation? Transplantation. ISSN 0041-1337. 100(12), p. 2705–2709. doi: 10.1097/TP.0000000000001363. Show summary

  BACKGROUND: Elderly patients are the fastest growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their eightieth year or older at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation? METHODS: Recipients in their eightieth year or older, transplanted between 1983 and 2015, were included. Data were retrieved from the Norwegian Renal Registry in the end of October 2015. Graft and patient survival were compared to recipients aged 70-79 years at transplantation. RESULTS: 47 patients older than 79 years were transplanted in the defined period. Median age 80.1 years, 81 % were male. Median time on dialysis prior to transplantation was 18.5 months. All patients received an allograft from a deceased donor (median donor age 61.8 years). In the death censored graft survival model, there was no statistical difference between the groups. We found improved patient and graft survival after introduction of mycophenolate mofetil and induction with basiliximab. Patients transplanted before 2000 had increased risk of death compared to those transplanted after 2000; HR 3.2 (95% CI 1.2-8.7). Median uncensored graft survival for patients transplanted after the year 2000 was 5.0 year (95% CI 2.4-7.6). Median patient survival was 5.0 years (3.1-6.9) and five year patient survival was 55 %. CONCLUSION: Age by itself should not be an absolute contraindication against renal transplantation. An estimated five years survival rate of 55 % post-engraftment for an 80 years old patient is in our opinion more than acceptable.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

• Dörje, Christina; Reisæter, Anna Varberg; Dahle, Dag Olav; Mjøen, Geir; Midtvedt, Karsten & Holdaas, Hallvard [Show all 12 contributors for this article] (2016). Total inflammation in early protocol kidney graft biopsies does not predict progression of fibrosis at one year post-transplant. Clinical Transplantation. ISSN 0902-0063. 30(7), p. 802–809. doi: 10.1111/ctr.12753.
• Meyer, Käthe Birgitte; Wahl, Astrid Klopstad; Bjørk, Ida Torunn; Wisløff, Torbjørn; Hartmann, Anders & Andersen, Marit Helen (2016). Long-term, self-reported health outcomes in kidney donors. BMC Nephrology. ISSN 1471-2369. 17(8). doi: 10.1186/s12882-016-0221-y.
• Eide, Ivar Anders; Dahle, Dag Olav; Svensson, My Hanna Sofia; Hartmann, Anders; Åsberg, Anders & Bjerve, Kristian S [Show all 11 contributors for this article] (2016). Plasma levels of marine n-3 fatty acids and cardiovascular risk markers in renal transplant recipients. European Journal of Clinical Nutrition. ISSN 0954-3007. 70(7), p. 824–830. doi: 10.1038/ejcn.2016.14.
• Lindahl, Jørn Petter Hanto; Hartmann, Anders; Aakhus, Svend; Endresen, Knut; Midtvedt, Karsten & Holdaas, Hallvard [Show all 10 contributors for this article] (2016). Long-term cardiovascular outcomes in type 1 diabetic patients after simultaneous pancreas and kidney transplantation compared with living donor kidney transplantation. Diabetologia. ISSN 0012-186X. 59(4), p. 844–852. doi: 10.1007/s00125-015-3853-8. Show summary

  Aims/hypothesis Mortality due to cardiovascular disease (CVD), particularly coronary artery disease (CAD), is high in type 1 diabetic patients with end-stage renal disease (ESRD). We aimed to determine whether normoglycaemia, as achieved by successful simultaneous pancreas and kidney (SPK) transplantation, could improve long-term outcomes compared with living donor kidney-alone (LDK) transplantation. Methods We studied 486 type 1 diabetic patients with ESRD who underwent a first SPK ( n =256)orLDK( n =230)trans- plant between 1983 and 2012 and were followed to the end of 2014. Data were retrieved from the Norwegian Renal Registry and hospital records. Kaplan – Meier plots and multivariate Cox regression, with correction for recipient, donor and trans- plant factors, were used to examine potential associations between transplant type and all-cause and CVD- and CAD- related mortality. Results Median follow-up time was 7.9 years (interquartile range 4.3, 12.9). The adjusted HR for CVD-related deaths in SPK recipients compared with LDK recipients was 0.63 (95% CI 0.40, 0.99; p =0.047), while the HRs for all-cause and CAD-related mortality were 0.81 (95% CI 0.57, 1.16; p =0.25) and 0.63 (95% CI 0.36, 1.12; p =0.12),respectively. Compared with the LDK group, SPK recipients were younger and received grafts from younger donors. Cardiovascular mor- tality was higher in patients transplanted between 1983 and 1999 compared with those who received their grafts in subse- quent years. Conclusions/interpretation In patients with type 1 diabetes and ESRD, SPK transplantation was associated with reduced long-term cardiovascular mortality compared with LDK transplantation.

• Eide, Ivar Anders; Jenssen, Trond Geir; Hartmann, Anders; Diep, Lien My; Dahle, Dag Olav & Reisæter, Anna Varberg [Show all 10 contributors for this article] (2016). Plasma levels of marine n-3 polyunsaturated fatty acids and renal allograft survival. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 31(1), p. 160–167. doi: 10.1093/ndt/gfv339.
• Jørgensen, Hanne Skou; Eide, Ivar Anders; Hartmann, Anders; Åsberg, Anders; Christensen, Jeppe H. & Schmidt, Erik B. [Show all 9 contributors for this article] (2016). Plasma n-3 Polyunsaturated Fatty Acids and Bone Mineral Density in Renal Transplant Recipients. Journal of renal nutrition. ISSN 1051-2276. 26(3), p. 196–203. doi: 10.1053/j.jrn.2015.11.007.
• Åsberg, Anders; Humar, Atul; Rollag, Halvor; Jardine, Alan G.; Kumar, Deepali & Aukrust, Pål [Show all 9 contributors for this article] (2016). Lessons Learned from a Randomized Study of Oral Valganciclovir Versus Parenteral Ganciclovir Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: The VICTOR Trial. Clinical Infectious Diseases. ISSN 1058-4838. 62(9), p. 1154–1160. doi: 10.1093/cid/ciw084.
• Strøm Halden, Thea Anine; Egeland, Erlend Johannessen; Åsberg, Anders; Hartmann, Anders; Midtvedt, Karsten & Khiabani, Hassan Zare [Show all 11 contributors for this article] (2016). GLP-1 restores altered insulin and glucagon secretion in posttransplantation diabetes. Diabetes Care. ISSN 0149-5992. 39(4), p. 617–624. doi: 10.2337/dc15-2383.
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Åsberg, Anders; Dahle, Dag Olav & Reisæter, Anna Varberg [Show all 7 contributors for this article] (2016). Mortality risk in post-transplantation diabetes mellitus based on glucose and HbA1c diagnostic criteria. Transplant International. ISSN 0934-0874. 29(5), p. 568–578. doi: 10.1111/tri.12757.
• Dahle, Dag Olav; Åsberg, Anders; Hartmann, Anders; Holdaas, Hallvard; Bachtler, Matthias & Jenssen, Trond Geir [Show all 8 contributors for this article] (2016). Serum calcification propensity is a strong and independent determinant of cardiac and all-cause mortality in kidney transplant recipients. American Journal of Transplantation. ISSN 1600-6135. 16(1), p. 204–212. doi: 10.1111/ajt.13443.
• Nordheim, Espen; Dahle, Dag Olav; Syse, Ingrid Marie; Åsberg, Anders; Reisæter, Anna Varberg & Hartmann, Anders (2016). Resolution of Calciphylaxis After Urgent Kidney Transplantation in 3 Patients With End-Stage Kidney Failure. Transplantation direct. ISSN 2373-8731. 2. doi: 10.1097/TXD.0000000000000627.
• Eide, Ivar Anders; Jenssen, Trond Geir; Hartmann, Anders; Diep, Lien My; Dahle, Dag Olav & Reisæter, Anna Varberg [Show all 10 contributors for this article] (2015). The association between marine n-3 polyunsaturated fatty acid levels and survival after renal transplantation. American Society of Nephrology. Clinical Journal. ISSN 1555-9041. 10(7), p. 1246–1256. doi: 10.2215/CJN.11931214.
• Lisboa, Luiz Filipe; Egli, Adrian; O'Shea, Daire; Åsberg, Anders; Hartmann, Anders & Rollag, Halvor [Show all 10 contributors for this article] (2015). Hcmv-miR-UL22A-5p: A biomarker in transplantation with broad impact on host gene expression and potential immunological implications. American Journal of Transplantation. ISSN 1600-6135. 15(7), p. 1893–1902. doi: 10.1111/ajt.13222.
• Jenssen, Trond A & Hartmann, Anders (2015). Emerging treatments for post-transplantation diabetes mellitus. Nature Reviews Nephrology. ISSN 1759-5061. 11(8), p. 465–477. doi: 10.1038/nrneph.2015.59.
• Smedbråten, Yuliya V.; Sagedal, Solbjørg; Mjøen, Geir; Hartmann, Anders; Fagerland, Morten & Rollag, Halvor [Show all 8 contributors for this article] (2015). High Ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients. Transplantation. ISSN 0041-1337. 99(4), p. 791–796. doi: 10.1097/TP.0000000000000422.
• Dahle, Dag Olav; Eide, Ivar Anders; Åsberg, Anders; Leivestad, Torbjørn; Holdaas, Hallvard & Jenssen, Trond Geir [Show all 10 contributors for this article] (2015). Aortic stiffness in a mortality risk calculator for kidney transplant recipients. Transplantation. ISSN 0041-1337. 99(8), p. 1730–1737. doi: 10.1097/TP.0000000000000660.
• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin & Eide, Ivar Anders [Show all 8 contributors for this article] (2015). Visceral fat is better related to impaired glucose metabolism than body mass index after kidney transplantation. Transplant International. ISSN 0934-0874. 28(10), p. 1162–1171. doi: 10.1111/tri.12606.
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Åsberg, Anders; Dahle, Dag Olav & Reisæter, Anna Varberg [Show all 7 contributors for this article] (2015). Limitations of hemoglobin A1c for the diagnosis of posttransplant diabetes mellitus. Transplantation. ISSN 0041-1337. 99(3), p. 629–635. doi: 10.1097/TP.0000000000000376.
• Reine, Trine M.; Kolseth, Ingrid Moss; Meen, Astri Jeanette; Lindahl, Jørn Petter Hanto; Jenssen, Trond Geir & Reinholt, Finn P. [Show all 10 contributors for this article] (2015). Effects of restoring normoglycemia in type 1 diabetes on inflammatory profile and renal extracellular matrix structure after simultaneous pancreas and kidney transplantation. Diabetes Research and Clinical Practice. ISSN 0168-8227. 107(1), p. 46–53. doi: 10.1016/j.diabres.2014.10.006.
• Ueland, Thor; Rollag, Halvor; Hartmann, Anders; Jardine, Alan G.; Humar, Atul & Bignamini, Angelo A [Show all 8 contributors for this article] (2015). Increased osteoprotegerin predicts poor virological outcome during anticytomegalovirus theapy in solid organ transplant recipients. Transplantation. ISSN 0041-1337. 99(1), p. 100–105. doi: 10.1097/TP.0000000000000227.
• Aulie, Hanne Aaserud; Selvaag, Anne Marit G; Günther, Anne; Lilleby, Vibke; Molberg, Øyvind & Hartmann, Anders [Show all 8 contributors for this article] (2015). Arterial haemodynamics and coronary artery calcification in adult patients with juvenile idiopathic arthritis. Annals of the Rheumatic Diseases. ISSN 0003-4967. 74(8), p. 1515–1521. doi: 10.1136/annrheumdis-2013-204804.
• Bleskestad, Inger Hjørdis; Bergrem, Harald; Leivestad, Torbjørn; Hartmann, Anders & Gøransson, Lasse G (2014). Parathyroid hormone and clinical outcome in kidney transplant patients with optimal transplant function. Clinical Transplantation. ISSN 0902-0063. 28(4), p. 479–486. doi: 10.1111/ctr.12341.
• Lindahl, Jørn Petter Hanto; Jenssen, Trond Geir & Hartmann, Anders (2014). Long-term outcomes after organ transplantation in diabetic end-stage renal disease. Diabetes Research and Clinical Practice. ISSN 0168-8227. 105(1), p. 14–21. doi: 10.1016/j.diabres.2014.03.004.
• Smedbråten, Yuliya V.; Sagedal, Solbjørg; Leivestad, Torbjørn; Mjøen, Geir; Osnes, Kåre & Rollag, Halvor [Show all 10 contributors for this article] (2014). The impact of early cytomegalovirus infection after kidney transplantation on long-term graft and patient survival. Clinical Transplantation. ISSN 0902-0063. 28(1), p. 120–126. doi: 10.1111/ctr.12288.
• Strøm Halden, Thea Anine; Åsberg, Anders; Vik, Karen; Hartmann, Anders & Jenssen, Trond Geir (2014). Short-term efficacy and safety of sitagliptin treatment in long-term stable renal recipients with new-onset diabetes after transplantation. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 29(4), p. 926–933. doi: 10.1093/ndt/gft536.
• Lindahl, Jørn Petter Hanto; Reinholt, Finn P.; Eide, Ivar Anders; Hartmann, Anders; Midtvedt, Karsten & Holdaas, Hallvard [Show all 13 contributors for this article] (2014). In patients with type 1 diabetes simultaneous pancreas and kidney transplantation preserves long-term kidney graft ultrastructure and function better than transplantation of kidney alone. Diabetologia. ISSN 0012-186X. doi: 10.1007/s00125-014-3353-2.
• Dahle, Dag Olav; Jenssen, Trond Geir; Holdaas, Hallvard; Åsberg, Anders; Soveri, Inga & Holme, Ingar Morten K [Show all 12 contributors for this article] (2014). Uric acid and clinical correlates of endothelial function in kidney transplant recipients. Clinical Transplantation. ISSN 0902-0063. 28(10), p. 1167–1176. doi: 10.1111/ctr.12435.
• Mjøen, Geir; Hallan, Stein; Hartmann, Anders; Foss, Aksel; Midtvedt, Karsten & Øyen, Ole [Show all 17 contributors for this article] (2014). Long-term risks for kidney donors. Kidney International. ISSN 0085-2538. 86(1), p. 162–167. doi: 10.1038/ki.2013.460.
• Ueland, Thor; Rollag, Halvor; Hartmann, Anders; Jardine, Alan George; Humar, Atul & Michelsen, Annika [Show all 9 contributors for this article] (2014). Secreted Wnt antagonists during eradication of cytomegalovirus infection in solid organ transplant recipients. American Journal of Transplantation. ISSN 1600-6135. 14(1), p. 210–215. doi: 10.1111/ajt.12506.
• Dahle, Dag Olav; Jenssen, Trond Geir; Holdaas, Hallvard; Leivestad, Torbjørn; Vårdal, Mari H & Mjøen, Geir [Show all 9 contributors for this article] (2014). Uric acid has a J-shaped association with cardiovascular and all-cause mortality in kidney transplant recipients. Clinical Transplantation. ISSN 0902-0063. 28(1), p. 134–140. doi: 10.1111/ctr.12290.
• Chen, Zhigang; Bouamar, Rachida; Van schaik, Ron H.N.; de Fijter, Johan W.; Hartmann, Anders & Zeier, Martin [Show all 11 contributors for this article] (2014). Genetic polymorphisms in IL-2, IL-10, TGF-β1, and IL-2RB and acute rejection in renal transplant patients. Clinical Transplantation. ISSN 0902-0063. 28(6), p. 649–655. doi: 10.1111/ctr.12346.
• Dörje, Christina; Midtvedt, Karsten; Holdaas, Hallvard; Naper, Christian; Strøm, Erik Heyerdahl & Øyen, Ole [Show all 13 contributors for this article] (2013). Early Versus Late Acute Antibody-Mediated Rejection in Renal Transplant Recipients. Transplantation. ISSN 0041-1337. 96(1), p. 79–84. doi: 10.1097/TP.0b013e31829434d4.
• Åsberg, Anders; Midtvedt, Karsten; van Guilder, Mike; Størset, Elisabet; Bremer, Sara & Bergan, Stein [Show all 9 contributors for this article] (2013). Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation. Transplant International. ISSN 0934-0874. 26(12), p. 1198–1207. doi: 10.1111/tri.12194.
• Holme, Ingar Morten K; Fellström, Bengt C; Jardine, Alan G.; Hartmann, Anders & Holdaas, Hallvard (2013). Model Comparisons of Competing Risk and Recurrent Events for Graft Failure in Renal Transplant Recipients. American Society of Nephrology. Clinical Journal. ISSN 1555-9041. 8(2), p. 241–247. doi: 10.2215/CJN.03760412.
• Rollag, Halvor; Ueland, Thor; Åsberg, Anders; Hartmann, Anders; Jardine, Alan G. & Humar, Atul [Show all 9 contributors for this article] (2013). Characterization of Cytomegalovirus Disease in Solid Organ Transplant Recipients by Markers of Inflammation in Plasma. PLOS ONE. ISSN 1932-6203. 8(4). doi: 10.1371/journal.pone.0060767.
• Lindahl, Jørn Petter Hanto; Hartmann, Anders; Horneland, Rune; Holdaas, Hallvard; Reisæter, Anna Varberg & Midtvedt, Karsten [Show all 9 contributors for this article] (2013). Improved patient survival with simultaneous pancreas and kidney transplantation in recipients with diabetic end-stage renal disease. Diabetologia. ISSN 0012-186X. 56(6), p. 1364–1371. doi: 10.1007/s00125-013-2888-y.
• Flechner, Stuart M.; Gurkan, Alihan; Hartmann, Anders; Legendre, Christophe M.; Russ, Graeme R. & Campistol, Josep M. [Show all 12 contributors for this article] (2013). A randomized, open-label study of sirolimus versus cyclosporine in primary de novo renal allograft recipients. Transplantation. ISSN 0041-1337. 95(10), p. 1233–1241. doi: 10.1097/TP.0b013e318291a269.
• Dahle, Dag Olav; Midtvedt, Karsten; Hartmann, Anders; Jenssen, Trond Geir; Holdaas, Hallvard & Mjøen, Geir [Show all 8 contributors for this article] (2013). Endothelial Dysfunction Is Associated With Graft Loss in Renal Transplant Recipients. Transplantation. ISSN 0041-1337. 95(5), p. 733–739. doi: 10.1097/TP.0b013e31827d6312.
• Åsberg, Anders; Apeland, Terje; Reisæter, Anna Varberg; Foss, Aksel; Leivestad, Torbjørn & Heldal, Kristian [Show all 9 contributors for this article] (2013). Long-term outcomes after cyclosporine or mycophenolate withdrawal in kidney transplantation – results from an aborted trial. Clinical Transplantation. ISSN 0902-0063. 27(2), p. E151–E156. doi: 10.1111/ctr.12076.
• Heldal, Kristian; Thorarinsdottir, Solveig; Hartmann, Anders; Leivestad, Torbjørn; Reisæter, Anna Varberg & Foss, Aksel [Show all 7 contributors for this article] (2013). Induction with interleukin-2 antagonist for transplantation of kidneys from older deceased donors: an observational study. Transplantation Research. ISSN 2047-1440. 2. doi: 10.1186/2047-1440-2-11.
• Tedesco-Silva, Helio; Kho, MML; Hartmann, Anders; Vitko, S; Russ, G. & Rostaing, L [Show all 12 contributors for this article] (2013). Sotrastaurin in Calcineurin Inhibitor-Free Regimen Using Everolimus in De Novo Kidney Transplant Recipients. American Journal of Transplantation. ISSN 1600-6135. 13(7), p. 1757–1768. doi: 10.1111/ajt.12255.

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• Mjøen, Geir; Reisæter, Anna Varberg; Hartmann, Anders; Dahle, Dag Olav & Holdaas, Hallvard (2019). Regarding age-calibrated glomerular filtration rate. Kidney International. ISSN 0085-2538. 95(1), p. 234–235. doi: 10.1016/j.kint.2018.10.003.
• Egeland, Erlend Johannessen; Størset, Elisabet; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten & Gustavsen, Marte Theie [Show all 10 contributors for this article] (2018). The Authors' Reply. Transplantation. ISSN 0041-1337. 102(1), p. e43–e44. doi: 10.1097/TP.0000000000001961.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Show all 12 contributors for this article] (2017). High tacrolimus clearance may predict rejection and chronic damage to the transplanted kidney.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Show all 12 contributors for this article] (2017). High tacrolimus clearance – a risk factor for acute rejection and fibrosis in the transplanted kidney.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Show all 12 contributors for this article] (2017). High tacrolimus clearance and acute rejection risk after renal transplantation.
• Egeland, Erlend Johannessen; Hermann, Monica; Robertsen, Ida; Midtvedt, Karsten; Hartmann, Anders & Reisæter, Anna Varberg [Show all 12 contributors for this article] (2016). High tacrolimus clearance is a risk factor for acute rejection early after renal transplantation.
• Smerud, Knut Terje; Dolgos, Szilviszter; Wiik, Lisa; Meland, Nils; Olsen, I. & Åsberg, Anders [Show all 12 contributors for this article] (2013). No Clinically Significant Effects of Calcium/ Calcitriol Supplementation on Loss of Bone Mass during the First Year after Renal Transplantation. American Journal of Transplantation. ISSN 1600-6135. 13, p. 208–208.
• Egli, A; Lisboa, L; O'Shea, D; Emery, V; Åsberg, Anders & Hartmann, Anders [Show all 8 contributors for this article] (2013). A Complex Host MicroRNA Response to Cytomegalovirus Infection: A Bench to Bedside Analysis. American Journal of Transplantation. ISSN 1600-6135. 13, p. 57–57.
• Aulie, Hanne Aaserud; Selvaag, Anne Marit G; Lilleby, Vibke; Molberg, Øyvind; Hartmann, Anders & Holdaas, Hallvard [Show all 7 contributors for this article] (2013). Increased Pulse Wave Velocity In Juvenile Idiopathic Arthritis Patients Compared To Controls From The General Population. Arthritis and Rheumatism. ISSN 0004-3591. 65, p. S1142–S1142.
• Mjøen, Geir; Hallan, Stein; Midtvedt, Karsten; Hartmann, Anders & Holdaas, Hallvard (2013). END STAGE RENAL DISEASE IN KIDNEY DONORS. Transplant International. ISSN 0934-0874. 26, p. 119–119.
• Åsberg, Anders; Midtvedt, Karsten; Guilder, Mikevan; Storset, Elisabet; Bremer, Sara & Bergan, Stein [Show all 9 contributors for this article] (2013). MARGINAL ADVANTAGE OF KNOWING PATIENT'S CYP3A5 GENOTYPE FOR TACROLIMUS DOSING. Transplant International. ISSN 0934-0874. 26, p. 198–198.
• Halden, Thea Anine Strøm; Åsberg, Anders; Hartmann, Anders & Jenssen, Trond Geir (2013). THE EFFECT OF SITAGLIPTIN TREATMENT ON HYPERGLYCEMIA AND INSULIN SECRETION AFTER RENAL TRANSPLANTATION. Transplant International. ISSN 0934-0874. 26, p. 175–176.
• Lindahl, Jørn Petter Hanto; Endresen, Knut; Gunther, Anne; Hartmann, Anders & Jenssen, Trond Geir (2013). Coronary artery disease in diabetic patients long-term after simultaneous pancreas and kidney transplantation compared with kidney transplantation alone. Diabetologia. ISSN 0012-186X. 56, p. S233–S233.
• Smedbraaten, Yuliya V.; Hartmann, Anders; Rollag, Halvor; Leivestad, Torbjørn; Foss, Aksel & Viko, Håvard [Show all 8 contributors for this article] (2012). LONG-TERM IMPACT OF EARLY CYTOMEGALOVIRUS INFECTION AFTER KIDNEY TRANSPLANTATION. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 27, p. 68–69.
• Lindahl, Jørn Petter Hanto; Hartmann, Anders; Midtvedt, Karsten; Leivestad, Torbjørn; Øyen, Ole & Jenssen, T (2012). Pancreas-Kidney Transplantation in Recipients with Diabetes End-Stage Kidney Disease Improve Long-Term Patient Survival. American Journal of Transplantation. ISSN 1600-6135. 12, p. 263–263.
• Midtvedt, Karsten; Loftheim, Håvard; Hartmann, Anders; Reisæter, Anna Varberg; Falck, Pål & Holdaas, Hallvard [Show all 9 contributors for this article] (2012). Urinary Proteomic Shotgun Approach for a Noninvasive Diagnosis of Acute Rejection of Renal Allografts. American Journal of Transplantation. ISSN 1600-6135. 12(supp. 3), p. 195–195.

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