Bjarne Bogen

Image of Bjarne Bogen
Norwegian version of this page
Visiting address Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postal address Postboks 4950 Nydalen OUS HF Rikshospitalet 0424 Oslo

Academic interests

Bjarne Bogen has an interest in  immunology of T and B lymphocytes,  autoimmune diseases, immunosurveillance of cancer, and development of more powerful vaccines. Below is a short overview of studies in which many co-workers contributed substantially over the years (see original research reports).

1. Idiotype-driven T-B collaboration, autoimmune diseases and development of B cell cancers. Idiotopes(Id) are antigenic determinants localized to immunoglobulin (Ig) Variable (V) regions.   Bogen described that B cells process their Ig receptor  (BCR) and that fragments of the variable (V) regions are presented on Major Histocompatibility Complex (MHC) class II molecules to Id-specific CD4+ T cells. This results in Id-driven T-B collaboration. In subsequent work, he showed that chronic Id-driven T-B collaboration could result in autoimmune diseases and development of B lymphomas (PNAS-89, EMBO-J-89, Cell-91, EMBO-J-93, EJI-99, JI -04, JI -05, JEM-07, Am J Pathol-09).

2. Immunosurveilance of cancer mediated by CD4+ T cells. Bogen showed that Id-specific TCR-transgenic mice resist challenges with Id+ B lymphoma cells and multiple myeloma cells. He showed that Ig secreted by the tumor cells were taken up by dendritic cells and macrophages infiltrating the tumor. These latter cells processed the monoclonal Ig and presented Id-peptides on their MHC II molecules to Id-specific CD4+ T cells that entered the tumor after first beeing stimulated in the draining lymph node. The tumor-infiltrating CD4+ T cells were of a Th1 type and secreted IFNg that activated macrophages to become cytotoxic to the cancer cells (PNAS-94, PNAS -00, Blood -01, Blood -03, Immunity -05, Cancer Res -09, Nat. Commun. -11)

3. Novel vaccine molecules: Troybodies and Vaccibodies. In Troybodies, T cell epitopes are inserted into loops between beta-strands in Ig constant domains. Next, such modified Ig is equipped with V-regions that target antigen presenting cells (APC). This results in enhanced T cell epitope presentation on MHC molecules of the APC,  and increasedT cell responses (Nat Biotech-89, PNAS-2001, JI -02, JI-03, EJI-05 etc.). In Vaccibodies, large antigens with intact B cell determinants are inserted into  Ig-based homodimers. The Vaccibodies are targeted to APC either by use of natural ligands or scFv specific for APC. Vaccibodies increase both antibody and T cells responses.  They may be administered as DNA vaccines. Currently, vaccibodies are developed for a number of differents diseases such as influenza, HIV, tubeculosis and certain cancers.(Mol Ther -06, JI -07, Blood -07, Vaccine -10, Eur J Hematol -11).

Courses taught

  • Bjarne Bogen is responsible for the teaching programme in immunology at The Medical Faculty
  • He mainly teaches basic immunology in the 3. semester
  • He has, together with Ludvig Munthe, written a textbook in immunology (Immunologi, Universitetsforlaget, 2000, 2nd edition 2007)


1977 - MD, University of Oslo

1977-78 Intern (surgery, internal medicine, general practice) at Sandnassjøen Hospital and Lurøy/Træna.

1979-1984 PhD student ans assistent professor, University of Tromsø

1984: PhD University of Tromsø

1985 and parts of 86 and 87: Member and visitor, Basel Institute for Immunology

1986 - present: Associate professor and professor (1993), the Medical Faculty, University of Oslo

1991: Specialist in Immunology and transfusion Medicine (the Norwegian Medical Association).

1995 - present: Senior consultant, Oso University Hospital -Rikshospitalet

1989 - 2004: Adjunct professor, Norwegian college of Veterinary Medicine

1996-97: Sabbatical at Stanford University

2004-2005: Sabbatical at Dana Farber Cancer Institute/Harvard University


  •  Innovation Prize , University of Oslo/The Oslo Research Park
  • The Medinnova Prize
  • The Tano-Aschehoug Prize
  • Senior Research Award, U.S. Multiple Myeloma Research Foundation


Bjarne Bogen has over the years collaborated with numerous investigators and labs as should be clear from the list of publications. His research group is presently member of the CoE Centre for Immune Immune Regulation sponsered by the Research Council of Norway.

Tags: Life sciences, Immunology, autoimmunity, B cell lymphomas, multiple myeloma, T cells, B cells, vaccine molecules, China, India, Japan, USA, Nordic, Global South


            Weiss S, Bogen B (1989) B lymphoma cells process and present their endogenous immunoglobulin to MHC-restricted T cells. Proc Natl Acad Sci USA 86:282-287


            Bogen B, Lambris JD (1989) Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule. EMBO Journal 8:1947-1952


            Weiss S, Bogen B (1991) MHC class II-restricted presentation of intracellular antigen. Cell 64:767-776


            Bogen B, Dembic Z, and Weiss S (1993) Clonal  deletion of specific thymocytes by an immunoglobulin idiotype.EMBO Journal 12:357-363


            Lauritzsen G.F, Weiss S, Dembic Z, and Bogen B (1994) Naive idiotype-specific CD4+ T cells and immunosurveillance of B cell tumors.Proc Natl Acad Sci USA 91:5700-5704


            Lunde, E., Munthe, L.A., Vabø, A. Sandlie, I, Bogen, B (1999). Antibodies engineered with anti IgD-specificity efficiently deliver integrated T cell epitopes for antigen presentation by B cells.  Nature Biotechnology, 17:670-75


            Djerbi, M., Screpanti, V., Anca,IC, Bogen, B., Biberfeld, P. and Grandien, A (1999). The inhibitor of death receptor signaling FLIP defines a new class of tumor progression factors. J.Exp.Med.  190: 1025-1031


            Dembic,Z, Schenk, K., , Bogen, B (2000). Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells. Proc.Natl. Acad. Sci (U.S.A). 97:2697-2702.


            Dembic, Z., Røttingen, J-A, Dellacasagrande, J. Schenk, K., Bogen, B.(2001)Phagocytic dendritic cells from myelomas activate tumor-specific T cells at a single cell level. Blood, 97:2808-2814


            Rasmussen, IB, Lunde, E., Michaelsen. TE. Bogen, B. Sandlie, I (2001). A new principle for delivery of T cell epitopes to antigen presenting cells applied to peptides from influenza virus, ovalbumin and hen egg lysozyme: Implications for peptide  

            vaccination. Proc.Natl. Acad. Sci (U.S.A). 98: 10296-10301                  


            Lunde E., Western K.H., Rasmussen I B., Sandlie I, Bogen B (2002). Efficient delivery of T-cell epitopes to APC by use of MHC class II-specific antibodies. J. Immunol. 168:2154-2162


            Lundin KU, Hofgaard PO, Omholt H, Munthe, LA, Corthay A, Bogen B (2003). Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies. Blood 102:605-612, 2003


           Schjetne, K.W., Thompson K.M., Fleckenstein B., Aarvak T., Flo T.H., Iversen J.G:, Espevik T., Bogen B (2003). Cutting edge: Link between innate and adaptive immunity: Toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cells.  

           J.  Immunol. 171: 32–36, 2003.


           Munthe, L A., Os, A., Zangani, M, Bogen, B. MHC-Restricted Ig V Region-Driven T-B Lymphocyte Collaboration: B Cell Receptor Ligation Facilitates Switch to IgG Production.


           J .Immunol 2004 Jun 15;172(12):7476-84.


           Corthay A, Skovseth DK, Lundin KU, Rosjo E, Omholt H, Hofgaard PO, Haraldsen G, Bogen B. Primary Antitumor Immune Response Mediated by CD4(+) T Cells. Immunity. 2005 Mar;22(3):371-83.


          Munthe, LA, Corthay, A, Os, A, Zangani, M, Bogen, B:systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig v-region-specific T cells. J. Immunol 2005, 15. 175, 2391-400


           FredriksenAB, Sandlie I,  Bogen B. DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen presenting cells. Mol Ther. 2006 Apr;13(4):776-85.


                      Husebye, H, Halaas, O, Stenmark, H, Tunheim, G, Sandanger, O, Bogen, B, Brech, A, Latz, E, Espevik, T. Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO-J 2006 Feb 22;25(4):683-92.


           Schjetne, KW, Fredriksen, AB, Bogen, B .Delivery of antigen to CD40 induces protective immune responses against tumors. J Immunol. 2007 , 178: 4169-76.


          Zangani MM, Frøyland M., Qui, GY, Meza-Zepeda, LA, Kutok, JL, Thompson, KM, Munthe LA, Bogen, B. Lymphomas can develop from B cells chronically helped by idiotype-specific T cells. J.Exp.Med. 2007, 204:1189-91.


         Fredriksen, AB, Bogen B. Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences. Blood. 2007, 110(6):1797-805


         Flobakk, M, Rasmussen, I, Lunde, E, Frigstad, T, Berntzen, G, Michaelsen, TE, Bogen, B, Sandlie, I.Processing of an Antigenic Sequence from IgG Constant Domains for Presentation by MHC Class II.  J Immunol. 2008 Nov 15;181(10):7062-72


        Zangani, M; Carlsen, H; Kielland, A; Os, A; Hauglin, H, Blomhoff, R; Munthe, LA,Bogen, B. Tracking early autoimmune disease by bioluminescent imaging of NF-kB activation reveals pathology in multiple organ systems. Am. J. Pathol. 2009, 174: 1358- 1367.


        Corthay, A, Lundin, K, Lorvik KB,Hofgaard, PO, Bogen, B. Secretion of tumor-specific antigen by myeloma cells enhances cancer immunosurveillance by CD4+ T cells. Cancer Research, 2009 Jul 15;69(14):5901-7.


      Jacobsen JT, Lunde E, Sundvold-Gjerstad V, Munthe LA, Bogen B. The celllular mechanism by which complementary Id(+) and anti-Id antibodies communicate: T cells integrated into idiotypic regulation ..Immunol Cell Biol.88: 515-22, 2010.


       Holmøy, T, vartdal, V, Hestvik, AL, Munthe, LA, Bogen, B. the idiotypic connection: linking infection and multiple sclerosis. Trends Immunol 2010, 31: 56-62


        Ruffini PA, Grødeland G, Fredriksen, Bogen, B: Human chemokine MIP1aincreases efficiency of targeted DNA fusion vaccines. Vaccine 2010 Dec 16;29(2):191-9.


        Haabeth OAW, Lorvik KB, Hammarström C, Donaldson IM, Haraldsen G, Bogen B, Corthay A. Inflammation driven by tumor-specific Th1 cells protects against B-cell cancer. Nat Commun. 2011 Mar;2:240.

  • Jung, Keunok; Jeon, You-kyoung; Jeong, Dae Hoon; Byun, Jung Mi; Bogen, Bjarne & Choi, Inhak (2022). VSIG4-expressing tumor-associated macrophages impair anti-tumor immunity. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 628, p. 18–24. doi: 10.1016/j.bbrc.2022.08.055.
  • Hinke, Daniëla Maria; Andersen, Tor Kristian; Gopalakrishnan, Ramakrishna Prabhu; Skullerud, Lise Madelene; Werninghaus, Ina Charlotta & Grødeland, Gunnveig [Show all 9 contributors for this article] (2022). Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses. Cell reports. ISSN 2211-1247. 39(9). doi: 10.1016/j.celrep.2022.110901.
  • Bekri, Selma; Rodney-Sandy, Reunet; Gruenstein, Diana; Mei, Anna; Bogen, Bjarne & Castle, John [Show all 8 contributors for this article] (2022). Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens. Journal for ImmunoTherapy of Cancer (JITC). 10(2). doi: 10.1136/jitc-2021-003572.
  • Tesfaye, Demo Yemane; Bobic, Sonja; Lysén, Anna Karin Christina; Huszthy, Peter Csaba; Gudjonsson, Arnar & Braathen, Ranveig [Show all 8 contributors for this article] (2022). Targeting Xcr1 on dendritic cells rapidly induce Th1-associated immune responses that contribute to protection against influenza infection. Frontiers in Immunology. ISSN 1664-3224. 13:752714, p. 1–13. doi: 10.3389/fimmu.2022.752714. Full text in Research Archive
  • He, Le; Valignat, Marie-Pierre; Zhang, Lichen; Gelard, Lena; Zhang, Fanghui & Le Guen, Valentin [Show all 17 contributors for this article] (2021). ARHGAP45 controls naïve T- and B- cell entry into lymph nodes and T-cell progenitor thymus seeding. EMBO Reports. ISSN 1469-221X. 22:e52196(4), p. 1–19. doi: 10.15252/embr.202052196. Full text in Research Archive
  • Bjerkan, Louise; Visweswaran, Ganesh Ram R.; Gudjonsson, Arnar; Labbé, Genevieve M.; Quinkert, Doris & Pattinson, David J. [Show all 10 contributors for this article] (2021). APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses. Frontiers in Immunology. ISSN 1664-3224. 12:720550(18), p. 1–13. doi: 10.3389/fimmu.2021.720550. Full text in Research Archive
  • Lysén, Anna Karin Christina; Gudjonsson, Arnar; Tesfaye, Demo Yemane; Bobic, Sonja; Bern, Malin C. & Bogen, Bjarne [Show all 7 contributors for this article] (2021). Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection. Scandinavian Journal of Immunology. ISSN 0300-9475. 95:e13128(3), p. 1–12. doi: 10.1111/sji.13128. Full text in Research Archive
  • Andersen, Tor Kristian; Bodin, Johanna Eva; Oftung, Fredrik; Bogen, Bjarne; Mjaaland, Siri & Grødeland, Gunnveig (2021). Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief. Frontiers in Immunology. ISSN 1664-3224. 12. doi: 10.3389/fimmu.2021.747032. Full text in Research Archive
  • Szodoray, Peter; Andersen, Tor Kristian; Heinzelbecker, Julia; Imbery, John Franklin; Huszthy, Peter C. & Stanford, Stephanie M. [Show all 12 contributors for this article] (2021). Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell reports. ISSN 2211-1247. 36:109525(6), p. 1–24. doi: 10.1016/j.celrep.2021.109525. Full text in Research Archive
  • Ziouti, Fani; Rummler, Maximilian; Steyn, Beatrice; Thiele, Tobias; Seliger, Anne & Duda, Georg N. [Show all 9 contributors for this article] (2021). Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton’s Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease. International Journal of Molecular Sciences. ISSN 1661-6596. 22:3840(8), p. 1–14. doi: 10.3390/ijms22083840. Full text in Research Archive
  • Høydahl, Lene; Frigstad, Terje; Rasmussen, Ingunn B; Øynebråten, Inger; Schjetne, Karoline W & Andersen, Jan Terje [Show all 10 contributors for this article] (2021). Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses. Vaccine. ISSN 0264-410X. 39(11), p. 1583–1592. doi: 10.1016/j.vaccine.2021.02.012. Full text in Research Archive
  • Rummler, Maximilian; Ziouti, Fani; Bouchard, Alice L.; Brandl, Andreas; Duda, Georg N. & Bogen, Bjarne [Show all 10 contributors for this article] (2020). Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease. Acta Biomaterialia. ISSN 1742-7061. 119, p. 247–258. doi: 10.1016/j.actbio.2020.10.041.
  • Ziouti, Fani; Soares, Ana Prates; Moreno-Jiménez, Inés; Rack, Alexander; Bogen, Bjarne & Cipitria, Amaia [Show all 8 contributors for this article] (2020). An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix. Journal of Oncology. ISSN 1687-8450. 2020:3985315, p. 1–12. doi: 10.1155/2020/3985315. Full text in Research Archive
  • Kwon, Minsuk; Kim, Chang Gon; Lee, Hoyoung; Cho, Hyunsoo; Kim, Youngun & Lee, Eung Chang [Show all 17 contributors for this article] (2020). PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors. Clinical Cancer Research. ISSN 1078-0432. 26(7), p. 1644–1655. doi: 10.1158/1078-0432.CCR-19-0267.
  • Grødeland, Gunnveig; Baranowska-Hustad, Marta Natalia; Abadejos, Justin; Blane, Tanja R.; Teijaro, John & Nemazee, David [Show all 7 contributors for this article] (2020). Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin. Frontiers in Immunology. ISSN 1664-3224. 11:431, p. 1–13. doi: 10.3389/fimmu.2020.00431. Full text in Research Archive
  • Fossum, Even; Tesfaye, Demo Yemane; Bobic, Sonja; Gudjonsson, Arnar; Braathen, Ranveig & Lahoud, Mireille H. [Show all 8 contributors for this article] (2020). Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response . Journal of Immunology. ISSN 0022-1767. 205(3), p. 661–673. doi: 10.4049/jimmunol.1901119.
  • Braathen, Ranveig; Spång, Heidi Cecilie Larsen; Hinke, Daniëla Maria; Blazevski, Jana; Bobic, Sonja & Fossum, Even [Show all 7 contributors for this article] (2020). A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza . Molecular therapy. Methods & clinical development. ISSN 2399-6951. 17, p. P378–P392. doi: 10.1016/j.omtm.2020.01.007. Full text in Research Archive
  • Haabeth, Ole Audun; Hennig, Kjartan; Fauskanger, Marte; Løset, Geir Åge; Bogen, Bjarne & Tveita, Anders Aune (2020). CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages. Blood Advances. ISSN 2473-9529. 4(12), p. 2595–2605. doi: 10.1182/bloodadvances.2020001434. Full text in Research Archive
  • Baghdadi, Muhammad; Ishikawa, Kozo; Nakanishi, Sayaka; Murata, Tomoki; Umeyama, Yui & Kobayashi, Takuto [Show all 20 contributors for this article] (2019). A role for IL-34 in osteolytic disease of multiple myeloma. Blood Advances. ISSN 2473-9529. 3(4), p. 541–551. doi: 10.1182/bloodadvances.2018020008. Full text in Research Archive
  • Grødeland, Gunnveig; Fossum, Even & Bogen, Bjarne (2019). Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs. Vaccine. ISSN 0264-410X. 38(6), p. 1280–1285. doi: 10.1016/j.vaccine.2019.11.084. Full text in Research Archive
  • Mahalunkar, Sneha; Yadav, Amit Singh; Gorain, Mahadeo; Pawar, Vinay; Braathen, Ranveig & Weiss, Siegfried [Show all 9 contributors for this article] (2019). Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer. International Journal of Nanomedicine. ISSN 1176-9114. 14, p. 8285–8302. doi: 10.2147/IJN.S215142. Full text in Research Archive
  • Høglund, Rune Alexander; Torsetnes, Silje Bøen; Lossius, Peter Andreas Vold; Bogen, Bjarne; Homan, E. Jane & Bremel, Robert [Show all 7 contributors for this article] (2019). Human cysteine cathepsins degrade immunoglobulin G in vitro in a predictable manner. International Journal of Molecular Sciences. ISSN 1661-6596. 20:4843(19), p. 1–19. doi: 10.3390/ijms20194843. Full text in Research Archive
  • Huszthy, Peter Csaba; Gopalakrishnan, Ramakrishna Prabhu; Jacobsen, Johanne Tracey; Haabeth, Ole Audun; Løset, Geir Åge & Braathen, Ranveig [Show all 10 contributors for this article] (2019). B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 116(51), p. 25850–25859. doi: 10.1073/pnas.1902836116. Full text in Research Archive
  • Bogen, Bjarne; Fauskanger, Marte; Haabeth, Ole Audun & Tveita, Anders Aune (2019). CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models. Cancer Immunology and Immunotherapy. ISSN 0340-7004. 68(11), p. 1865–1873. doi: 10.1007/s00262-019-02374-0. Full text in Research Archive
  • Tesfaye, Demo Yemane; Gudjonsson, Arnar; Bogen, Bjarne & Fossum, Even (2019). Targeting conventional dendritic cells to fine-tune antibody responses. Frontiers in Immunology. ISSN 1664-3224. 10:1529(JULY), p. 1–8. doi: 10.3389/fimmu.2019.01529. Full text in Research Archive
  • Gudjonsson, Arnar; Andersen, Tor Kristian; Gjerstad, Vibeke Sundvold; Bogen, Bjarne & Fossum, Even (2019). Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice. Frontiers in Immunology. ISSN 1664-3224. 10, p. 1–12. doi: 10.3389/fimmu.2019.01086. Full text in Research Archive
  • Andersen, Tor Kristian; Huszthy, Peter Csaba; Gopalakrishnan, Ramakrishna Prabhu; Jacobsen, Johanne Tracey; Fauskanger, Marte & Tveita, Anders Aune [Show all 8 contributors for this article] (2019). Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules. npj Vaccines. ISSN 2059-0105. 4:9, p. 1–13. doi: 10.1038/s41541-019-0101-0. Full text in Research Archive
  • Lysén, Anna Karin Christina; Braathen, Ranveig; Gudjonsson, Arnar; Tesfaye, Demo Yemane; Bogen, Bjarne & Fossum, Even (2019). Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site. Scientific Reports. ISSN 2045-2322. 9:1820, p. 1–11. doi: 10.1038/s41598-018-38080-7. Full text in Research Archive
  • Mooij, Petra; Grødeland, Gunnveig; Koopman, Gerrit; Andersen, Tor Kristian; Mortier, Daniella & Nieuwenhuis, Ivonne G. [Show all 10 contributors for this article] (2019). Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza. Vaccine. ISSN 0264-410X. 37(6), p. 817–826. doi: 10.1016/j.vaccine.2018.12.049. Full text in Research Archive
  • Abrahamsen, Greger; Gjerstad, Vibeke Sundvold; Mekonnen, Meseret; Bogen, Bjarne & Spurkland, Anne (2018). Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd. Scientific Reports. ISSN 2045-2322. 8:13319, p. 1–13. doi: 10.1038/s41598-018-31510-6. Full text in Research Archive
  • Haabeth, Ole Audun; Fauskanger, Marte; Manzke, Melanie; Lundin, Katrin; Corthay, Alexandre & Bogen, Bjarne [Show all 7 contributors for this article] (2018). CD4+ T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs. Cancer Research. ISSN 0008-5472. 78(16), p. 4573–4585. doi: 10.1158/0008-5472.CAN-17-2426.
  • Fauskanger, Marte; Haabeth, Ole Audun; Skjeldal, Frode Miltzow; Bogen, Bjarne & Tveita, Anders (2018). Tumor killing by CD4+ T cells is mediated via induction of inducible nitric oxide synthase-dependent macrophage cytotoxicity. Frontiers in Immunology. ISSN 1664-3224. 9:1684, p. 1–13. doi: 10.3389/fimmu.2018.01684. Full text in Research Archive
  • Braathen, Ranveig; Spång, Heidi Cecilie Larsen; Lindeberg, Mona Mari; Fossum, Even; Grødeland, Gunnveig & Fredriksen, Agnete [Show all 7 contributors for this article] (2018). The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccine Are Influenced by Specificity for APC Surface Molecules. ImmunoHorizons. ISSN 2573-7732. 2(1), p. 38–53. doi: 10.4049/immunohorizons.1700038. Full text in Research Archive
  • Anderson, Ane Marie; Baranowska-Hustad, Marta Natalia; Braathen, Ranveig; Grødeland, Gunnveig & Bogen, Bjarne (2018). Simultaneous targeting of multiple hemagglutinins to APCs for induction of broad immunity against influenza. Journal of Immunology. ISSN 0022-1767. 200(6), p. 2057–2066. doi: 10.4049/jimmunol.1701088.
  • Andersen, Tor Kristian; Zhou, Fan; Cox, Rebecca Jane; Bogen, Bjarne & Grødeland, Gunnveig (2017). A DNA vaccine that targets hemagglutinin to antigen-presenting cells protects mice against H7 influenza. Journal of Virology. ISSN 0022-538X. 91:e01340-17(23), p. 1–13. doi: 10.1128/JVI.01340-17. Full text in Research Archive
  • Wang, Dong; Fløisand, Yngvar; Myklebust, Camilla Victoria; Bürgler, Simone; Ribes, Anna Maria Parente & Hofgaard, Peter Olaf [Show all 13 contributors for this article] (2017). Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice. Leukemia. ISSN 0887-6924. 31(10), p. 2114–2121. doi: 10.1038/leu.2017.69. Full text in Research Archive
  • Deloizy, Charlotte; Fossum, Even; Barnier-Quer, Christophe; Urien, Céline; Chrun, Tiphany & Duval, Audrey [Show all 19 contributors for this article] (2017). The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin. Scientific Reports. ISSN 2045-2322. 7:7639, p. 1–12. doi: 10.1038/s41598-017-07372-9.
  • Høglund, Rune Alexander; Lossius, Peter Andreas Vold; Johansen, Jorunn; Homan, Jane; Saltyte Benth, Jurate & Robins, Harlan [Show all 9 contributors for this article] (2017). In silico prediction analysis of idiotope-driven T-B cell collaboration in multiple sclerosis. Frontiers in Immunology. ISSN 1664-3224. 8. doi: 10.3389/fimmu.2017.01255. Full text in Research Archive
  • Park, Bo Mi; Kim, Eun Jin; Nam, Hye Yeon; Zhang, Dongdong; Bae, Chu Hyun & Kang, Myeongmo [Show all 10 contributors for this article] (2017). Cyclized oligopeptide targeting LRP5/6-DKK1 interaction reduces the growth of tumor burden in a multiple myeloma mouse model. Yonsei medical journal. ISSN 0513-5796. 58(3), p. 505–513. doi: 10.3349/ymj.2017.58.3.505.
  • Gudjonsson, Arnar; Lysén, Anna Karin Christina; Balan, Sreekumar; Gjerstad, Vibeke Sundvold; Arnold-Schrauf, Catharina & Richter, Lisa Maria [Show all 10 contributors for this article] (2017). Targeting influenza virus hemagglutinin to Xcr1+ dendritic cells in the absence of receptor-mediated endocytosis enhances protective antibody responses. Journal of Immunology. ISSN 0022-1767. 198(7), p. 2785–2795. doi: 10.4049/jimmunol.1601881.
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Published Apr. 13, 2011 2:53 PM - Last modified June 2, 2016 1:36 PM