Ingrid Melle

Image of Ingrid Melle
Norwegian version of this page
Phone +47 23 02 73 50
Visiting address Building 49 Ullevål hospital Kirkeveien 166 Oslo
Postal address Building 49 Ullevål hospital Postboks 4956 Nydalen 0424 Oslo Norway

Academic interests

I am co-director of the NORMENT Centre and head of the Centre's "Illness trajectories and outcome prediction" research group. My current research is focused on:

  • Mechanisms associated with environmental risk factors, gene x environment interactions: early trauma, migration and cannabis.
  • Early illness phases in psychotic- and bipolar disorders, with a particular focus on negative symptoms and treatment response.
  • Risk factors for the development of chronic illness and premature death, in particular suicide risk.


Psychiatry; Medical students. 

Introductory course in psychosocial research methods; PhD students.


MD from the University of Trondheim 1981, licensed psychiatrist 1992, PhD from the University of Oslo 2000.

1992-2006: Clinical director at the  treatment centre for early psychosis treatment and assistant research director at the Dept for Research and Development,  Division of Psychiatry, Ullevål University Hospital.

2006-2012: Head of Psychosis Research Section, Ullevål University Hospital/Oslo University Hospital.

2010-2020: Professor II, University of Oslo.

2013-2020: Head of Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine.

2013-: Co-director,  NORMENT Centre.

2020-: Professor I, University of Oslo



With research groups in psychotic and bipolar disorders at the University Hospitals in Stavanger, Bergen and Trondheim.

With the researchers in bipolar disorders at the University of Paris- Diderot - Paris, France.

With researchers in schizophrenia at the UCLA Semel Institute, Los Angeles, CA.

With other European researchers into negative symptoms in schizophrenia through the research network EuroNES.

Tags: Schizophrenia, Bipolar disorder, Early psychosis, Negative symptoms, Environmental risk, Treatment response.


  • Aas, Monica; Ueland, Torill; Mørch, Ragni Helene; Laskemoen, Jannicke Fjæra; Lunding, Synve Hoffart; Reponen, Elina Johanna; Cattaneo, Annamaria; Agartz, Ingrid; Melle, Ingrid; Steen, Nils Eiel & Andreassen, Ole Andreas (2021). Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders. World Journal of Biological Psychiatry.  ISSN 1562-2975. . doi: 10.1080/15622975.2021.1907707
  • Hegelstad, Wenche ten Velden; Ottesen, Akiah; Bjørnestad, Jone Ravndal; Gismervik, Kristina; Johannessen, Jan Olav; Melle, Ingrid; Stain, Helen J. & Joa, Inge (2021). Childhood interpersonal trauma and premorbid social adjustment as predictors of symptom remission in first episode psychosis. Schizophrenia Research.  ISSN 0920-9964.  232, s 87- 94 . doi: 10.1016/j.schres.2021.05.015 Full text in Research Archive.
  • Lagerberg, Trine Vik; Icick, Romain; Aminoff, Sofie Ragnhild; Nerhus, Mari; Barrett, Elizabeth Ann; Bjella, Thomas; Olsen, Stine Holmstul; Høegh, Margrethe Collier & Melle, Ingrid (2021). Substance Misuse Trajectories and Risk of Relapse in the Early Course of Bipolar Disorder. Frontiers in Psychiatry.  ISSN 1664-0640.  12 . doi: 10.3389/fpsyt.2021.656912
  • Lunding, Synve Hoffart; Simonsen, Carmen Elisabeth; Aas, Monica; Rødevand, Linn; Werner, Maren Caroline Frogner; Laskemoen, Jannicke Fjæra; Hjell, Gabriela; Ringen, Petter Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Andreassen, Ole Andreas; Ueland, Torill & Steen, Nils Eiel (2021). Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control. European psychiatry.  ISSN 0924-9338.  64(1) . doi: 10.1192/j.eurpsy.2021.14
  • Værnes, Tor Gunnar; Røssberg, Jan Ivar; Melle, Ingrid; Nelson, Barnaby; Romm, Kristin Lie & Møller, Paul (2021). Basic self-disturbance in subjects at clinical high risk for psychosis: Relationship with clinical and functional outcomes at one year follow-up. Psychiatry Research.  ISSN 0165-1781.  300 . doi: 10.1016/j.psychres.2021.113942
  • Wolfers, Thomas; Rokicki, Jaroslav; Alnæs, Dag; Berthet, Pierre; Agartz, Ingrid; Kia, Seyed Mostafa; Kaufmann, Tobias; Zabihi, Mariam; Moberget, Torgeir; Melle, Ingrid; Beckmann, Christian F.; Andreassen, Ole Andreas; Marquand, Andre F. & Westlye, Lars Tjelta (2021). Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder. Human Brain Mapping.  ISSN 1065-9471.  42(8), s 2546- 2555 . doi: 10.1002/hbm.25386
  • Aas, Monica; Ueland, Torill; Inova, Amina; Melle, Ingrid; Andreassen, Ole Andreas & Steen, Nils Eiel (2020). Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder. Frontiers in Psychiatry.  ISSN 1664-0640. . doi: 10.3389/fpsyt.2020.00391 Full text in Research Archive.
  • Coleman, Jonathan R.I.; Gaspar, Helena A; Bryois, Julien; Byrne, Enda M; Forstner, Andreas J; Holmans, Peter A; de Leeuw, Christiaan A.; Mattheisen, Manuel; McQuillin, Andrew; Whitehead Pavlides, Jennifer M; Pers, Tune H; Ripke, Stephan; Stahl, Eli A.; Steinberg, Stacy; Trubetskoy, Vassily; Trzaskowski, Maciej; Wang, Yunpeng; Abbott, Liam; Abdellaoui, Abdel; Adams, Mark J; Nordin Adolfsson, Annelie; Agerbo, Esben; Akil, Huda; Albani, Diego; Alliey-Rodriguez, Ney; Als, Thomas D.; Andlauer, Till F.M.; Anjorin, Adebayo; Anttila, Verneri; Van Der Auwera, Sandra; Awasthi, Swapnil; Bacanu, Silviu-Alin; Badner, Judith A.; Bækvad-Hansen, Marie; Barchas, Jack D.; Bass, Nicholas; Bauer, Michael; Beekman, Aartjan T.F.; Belliveau, Richard; Bøen, Erlend; Djurovic, Srdjan; Elvsåshagen, Torbjørn; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Melle, Ingrid; Morken, Gunnar; Ødegaard, Ketil Joachim; Stordal, Eystein; Vaaler, Arne; Andreassen, Ole Andreas & Breen, Gerome (2020). The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Biological Psychiatry.  ISSN 0006-3223. . doi: 10.1016/j.biopsych.2019.10.015 Show summary

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  • Andreassen, Ole Andreas; Malt, Ulrik Fredrik; Malt, Eva Albertsen & Melle, Ingrid (2020). Lærebok i psykiatri Basisversjon. Gyldendal Norsk Forlag A/S.  ISBN 978-82-05-52662-4.  519 s.

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  • Vaskinn, Anja; Sundet, Kjetil; Melle, Ingrid; Andreassen, Ole A. & Friis, Svein (2021). The factor structure of social cognition in schizophrenia: Weak evidence for separable domains. Schizophrenia Research: Cognition.  ISSN 2215-0013.  26, s 1- 4 . doi: 10.1016/j.scog.2021.100208 Show summary

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Published Apr. 13, 2011 2:54 PM - Last modified Jan. 11, 2021 3:58 PM