Ingrid Melle

Professor

Norwegian version of this page

Email ingrid.melle@medisin.uio.no

Phone +47 23 02 73 50

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Visiting address Sognsvannsveien 21 Building 4

Postal address P.O. Box 1039 Blindern 0315 Oslo Norway

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Academic interests

My research is based in the NORMENT K.G. Jebsen Centre for Psychosis Research as co-director and head of the Illnes trajectories and outcome prediction research group. My initial research background was from the first generation of early intervention in psychosis studies. This experience raised my interest in the development of psychotic disorders; in particular environmental risk factors, early illness phases and how these shape long-term course and outcome. My current research is focused on:

Mechanisms associated with environmental risk factors, gene x environment interactions: early trauma, migration and cannabis.
Early illness phases in schizophrenia and bipolar disorders, with a particular focus on negative symptoms, emotional dysregulation, cognitive- and social dysfunction.
Risk factors for the development of chronic illness and premature death, in particular suicide risk.

Teaching

Psychiatry; Medical students.

Introductory research course in mental – and substance use disorders; PhD students.

Background

MD from the University of Trondheim 1981, licensed psychiatrist 1992, PhD from the University of Oslo 2000.

1992-2006: Clinical director at Lien Treatment Centre for early psychosis treatment and assistant research director at the Dept for Research and Development, Division of Psychiatry, Ullevål University Hospital (“TIPS project”)

2006-2012: Head of Psychosis Research Section, Ullevål University Hospital/Oslo University Hospital

2010-: Professor II, University of Oslo.

2013-: Co-director, NORMENT K.G.Jebsen Centre for Psychosis Research.

2013-: Head of Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine.

Appointments

Member of Scientific Advisory Board for the South-Eastern Norway Regional Health Authority. Member of steering groups for the Norwegian Network for Severe Mental Illnesses (“NORSMI”).

Collaborations

Leader of Regional Research Network Psychotic Disorders (with Ahus, Vestfold, Vestre Viken and Innlandet).

Main ongoing research collaborations:

With research groups in schizophrenia and bipolar disorders at the University Hospitals in Stavanger, Bergen, Trondheim and Tromsø. (“NASATS”).

With the researchers in bipolar disorders at the Hopital Albert Chenevier/ INSERM - Institut Mondor de Recherche Biomedicale, Creteil, Frankrike.

With researchers in schizophrenia at the UCLA Semel Institute, Los Angeles, CA and Yale University School of Medicine, New Haven, CT, USA.

With other European researchers into negative symptoms in schizophrenia through the research network EuroNES.

Tags: Nordic, USA

Aas, Monica; Elvsåshagen, Torbjørn; Westlye, Lars Tjelta; Kaufmann, Tobias; Athanasiu, Lavinia; Djurovic, Srdjan; Melle, Ingrid; van der Meer, Dennis; Martin-Ruiz, Carmen; Steen, Nils Eiel; Agartz, Ingrid & Andreassen, Ole Andreas (2019). Telomere length is associated with childhood trauma in patients with severe mental disorders. Translational psychiatry. ISSN 2158-3188. 9 . doi: 10.1038/s41398-019-0432-7
Aas, Monica; Pizzagalli, Diego A.; Anderssen, Jannicke Fjæra; Reponen, Elina Johanna; Ueland, Torill; Melle, Ingrid; Agartz, Ingrid; Steen, Nils Eiel & Andreassen, Ole Andreas (2019). Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders. Schizophrenia Research. ISSN 0920-9964. . doi: 10.1016/j.schres.2019.01.011
Bjørnestad, Jone Ravndal; Hegelstad, Wenche; Berg, Henrik; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Melle, Ingrid; Stain, Helen J. & Pallesen, Ståle (2019). Social media and social functioning in psychosis: A systematic review. Journal of Medical Internet Research. ISSN 1438-8871. 21:e13957(6), s 1- 22 . doi: 10.2196/13957
Di Sero, Alessia; Jørgensen, Kjetil Nordbø; Nerland, Stener; Melle, Ingrid; Andreassen, Ole Andreas; Jovicich, Jorge & Agartz, Ingrid (2019). Antipsychotic treatment and basal ganglia volumes: Exploring the role of receptor occupancy, dosage and remission status. Schizophrenia Research. ISSN 0920-9964. 208, s 114- 123 . doi: 10.1016/j.schres.2019.04.002
Ferrara, Maria; Guloksuz, Sinan; Li, Fangyong; Burke, Shadie; Tek, Cenk; Friis, Svein; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Melle, Ingrid; Simonsen, Erik & Srihari, Vinod H. (2019). Parsing the impact of early detection on duration of untreated psychosis (DUP): Applying quantile regression to data from the Scandinavian TIPS study. Schizophrenia Research. ISSN 0920-9964. . doi: 10.1016/j.schres.2019.05.035
Gjerde, Priyanthi Borgen; Simonsen, Carmen Elisabeth; Lagerberg, Trine Vik; Steen, Nils Eiel; Ueland, Torill; Andreassen, Ole Andreas; Steen, Vidar Martin & Melle, Ingrid (2019). Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients. European Archives of Psychiatry and Clinical Neuroscience. ISSN 0940-1334. s 1- 10 . doi: 10.1007/s00406-019-01017-w
Gohar, Sherif Mostafa Mohamed Ahmed; Dieset, Ingrid; Steen, Nils Eiel; Mørch, Ragni Helene; Vedal, Trude Seselie Jahr; Reponen, Elina Johanna; Steen, Vidar Martin; Andreassen, Ole Andreas & Melle, Ingrid (2019). Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 139(5), s 464- 471 . doi: 10.1111/acps.13019
Kaufmann, Tobias; van der Meer, Dennis; Doan, Nhat Trung; Schwarz, Emanuel; Lund, Martina Jonette; Agartz, Ingrid; Alnæs, Dag; Barch, Deanna M.; Baur-Streubel, Ramona; Bertolino, Alessandro; Bettella, Francesco; Beyer, Mona K.; Bøen, Erlend; Borgwardt, Stefan; Brandt, Christine Lycke; Buitelaar, Jan; Celius, Elisabeth Gulowsen; Cervenka, Simon; Conzelmann, Annette; Córdova-Palomera, Aldo; Dale, Anders; de Quervain, Dominique J.F.; di Carlo, Pasquale; Djurovic, Srdjan; Dørum, Erlend Solberg; Eisenacher, S.; Elvsåshagen, Torbjørn; Espeseth, Thomas; Fatouros-Bergman, Helena; Flyckt, Lena; Franke, Barbara; Frei, Oleksandr; Haatveit, Beathe; Håberg, Asta; Harbo, Hanne Flinstad; Hartman, Catharina A; Heslenfeld, Dirk J; Hoekstra, Pieter J; Høgestøl, Einar August; Jernigan, Terry L.; Jonassen, Rune; Jönsson, Erik Gunnar; Karolinska Schizophrenia Pro, KaSP; Kirsch, Peter; Kłoszewska, Iwona; Kolskår, Knut-Kristian; Landrø, Nils Inge; Le Hellard, Stephanie; Lesch, Klaus-Peter; Lovestone, Simon; Lundervold, Arvid; Lundervold, Astri; Maglanoc, Luigi Angelo; Malt, Ulrik Fredrik; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Moberget, Torgeir; Norbom, Linn Christin Bonaventure; Nordvik, Jan Egil; Nyberg, Lars; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pauli, Paul; Pergola, Giulio; Persson, Karin; Richard, Geneviève; Rokicki, Jaroslav; Sanders, Anne-Marthe; Selbæk, Geir; Shadrin, Alexey A.; Smeland, Olav Bjerkehagen; Soininen, Hilkka; Sowa, Piotr; Steen, Vidar Martin; Tsolaki, Magda; Ulrichsen, Kristine Moe; Vellas, Bruno; Wang, Lei; Westman, Eric; Ziegler, Georg C.; Zink, Mathias; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2019). Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. ISSN 1097-6256.
Laskemoen, Jannicke Fjæra; Simonsen, Carmen Elisabeth; Büchmann, Camilla Bakkalia; Barrett, Elizabeth Ann; Bjella, Thomas; Lagerberg, Trine Vik; Vedal, Trude Seselie Jahr; Andreassen, Ole Andreas; Melle, Ingrid & Aas, Monica (2019). Sleep disturbances in schizophrenia spectrum and bipolar disorders ? a transdiagnostic perspective. Comprehensive Psychiatry. ISSN 0010-440X. 91, s 6- 12 . doi: 10.1016/j.comppsych.2019.02.006
Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Reponen, Elina Johanna; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Gardsjord, Erlend Strand; Aas, Monica; Iversen, Trude; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Thor & Andreassen, Ole Andreas (2019). Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors. Psychological Medicine. ISSN 0033-2917. 49(10), s 1749- 1757 . doi: 10.1017/S0033291718004142
Romm, Kristin Lie; Gardsjord, Erlend Strand; Gjermundsen, Kristine; Aguirre, Manuela; Berentzen, Lars-Christian & Melle, Ingrid (2019). Designing easy access to care for first-episode psychosis in complex organizations. Early Intervention in Psychiatry. ISSN 1751-7885. . doi: 10.1111/eip.12802
Rødevand, Linn; Steen, Nils Eiel; Elvsåshagen, Torbjørn; Quintana, Daniel; Reponen, Elina Johanna; Mørch, Ragni Helene; Lunding, Synve Hoffart; Vedal, Trude Seselie Jahr; Dieset, Ingrid; Melle, Ingrid; Lagerberg, Trine Vik & Andreassen, Ole Andreas (2019). Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 139(4), s 348- 360 . doi: 10.1111/acps.13008 Show summary
Objective: While CVD risk has decreased in the general population during the last decade, the situation in patients with schizophrenia (SCZ) and bipolar disorder (BD) is unknown. Methods: We compared CVD risk factors in patients with SCZ and BD recruited from 2002‐2005 (2005 sample, N = 270) with patients recruited from 2006‐2017 (2017 sample, N = 1011) from the same catchment area in Norway. The 2017 sample was also compared with healthy controls (N = 922) and the general population (N range = 1285‐4587, Statistics Norway) from the same area and period. Results: Patients with SCZ and BD in the 2017 sample had significantly higher level of most CVD risk factors compared to healthy controls and the general population. There was no significant difference in the prevalence of CVD risk factors in SCZ between the 2005 and 2017 samples except a small increase in glucose in the 2017 sample. There were small‐to‐moderate reductions in hypertension, obesity, total cholesterol, low‐density lipoprotein, systolic and diastolic blood pressure in the BD 2017 sample compared to the 2005 sample. Conclusion: Despite major advances in health promotion during the past decade, there has been no reduction in the level of CVD risk factors in patients with SCZ and modest improvement in BD.
Stahl, Eli A.; Breen, Gerome; Forstner, Andreas J.; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Coleman, Jonathan R.I.; Gaspar, Héléna A.; de Leeuw, Christiaan A.; Steinberg, Stacy; Pavlides, Jennifer M. Whitehead; Trzaskowski, Maciej; Byrne, Enda M.; Pers, Tune H.; Holmans, Peter A.; Richards, Alexander L.; Abbott, Liam; Agerbo, Esben; Akil, Huda; Albani, Diego; Alliey-Rodriguez, Ney; Als, Thomas D.; Anjorin, Adebayo; Antilla, Verneri; Awasthi, Swapnil; Badner, Judith A.; Bækvad-Hansen, Marie; Barchas, Jack D.; Bass, Nicholas; Bauer, Michael; Belliveau, Richard; Bergen, Sarah E.; Pedersen, Carsten Bøcker; Bøen, Erlend; Boks, Marco P.; Boocock, James; Budde, Monika; Bunney, William; Burmeister, Margit; Bybjerg-Grauholm, Jonas; Byerley, William; Casas, Miquel; Cerrato, Felecia; Cervantes, Pablo; Chambert, Kimberly; Charney, Alxander W.; Chen, Danfeng; Churchhouse, Claire; Clarke, Toni-Kim; Coryell, William; Craig, David W.; Cruceanu, Cristiana; Curtis, David; Czerski, Piotr M.; Dale, Anders; de Jong, Simone; Degenhardt, Franziska; Del-Favero, Jurgen; Depaulo, J. Raymond; Djurovic, Srdjan; Dobbyn, Amanda L.; Dumont, Ashley; Elvsåshagen, Torbjørn; Escott-Price, Valentina; Fan, Chun Chieh; Fischer, Sascha B.; Flickinger, Matthew; Foroud, Tatiana M.; Forty, Liz; Frank, Josef; Fraser, Christine; Freimer, Nelson B.; Frisén, Louise; Gade, Katrin; Gage, Diane; Garnham, Julie; Giambartolomei, Claudia; Pedersen, Marianne Giørtz; Goldstein, Jaqueline; Gordon, Scott D.; Gordon-Smith, Katherine; Green, Elaine K.; Green, Melissa J.; Greenwood, Tifany A.; Grove, Jakob; Guan, Weihua; Guzman-Parra, José; Hamshere, Marian L.; Hautzinger, Martin; Heilbronner, Urs; Herms, Stefan; Hipolito, Maria; Hoffmann, Per; Holland, Dominic; Huckins, Laura; Jamain, Stéphane; Johnson, Jessica S.; Juréus, Anders; Kandaswamy, Radhika; Karlsson, Robert; Kennedy, James L.; Kittel-Schneider, Sarah; Knowles, James A.; Kogevinas, Manolis; Koller, Anna C.; Kupka, Ralph; Lavebratt, Catharina; Lawrence, Jacob; Lawson, William B.; Leber, Markus; Lee, Phil H.; Levy, Shawn E.; Li, Jun Z.; Liu, Chunyu; Lucae, Susanne; Maaser, Anna; MacIntyre, Donald J.; Mahon, Pamela B.; Maier, Wolfgang; Martinsson, Lina; McCarroll, Steve; McGuffin, Peter; McInnis, Melvin G.; McKay, James D.; Medeiros, Helena; Medland, Sarah E.; Meng, Fan; Milani, Lili; Montgomery, Grant W.; Morris, Derek W.; Mühleisen, Thomas W.; Mullins, Niamh; Nguyen, Hoang; Nievergelt, Caroline M.; Adolfsson, Annelie Nordin; Nwulia, Evaristus A.; O'Donovan, Claire; Loohuis, Loes M. Olde; Ori, Anil P.S.; Oruc, Lilijana; Ösby, Urban; Perlis, Roy H.; Perry, Amy; Pfennig, Andrea; Potash, James B.; Purcell, Shaun M.; Regeer, Eline J.; Reif, Andreas; Reinbold, Céline S.; Rice, John P.; Rivas, Fabio; Rivera, Margarita; Roussos, Panos; Ruderfer, Douglas M.; Ryu, Euijung; Sánchez-Mora, Cristina; Schatzberg, Alan F.; Scheftner, William A.; Schork, Nicholas J.; Shannon Weickert, Cynthia; Shehktman, Tatyana; Shilling, Paul D.; Sigurdsson, Engilbert; Slaney, Claire; Smeland, Olav Bjerkehagen; Sobell, Janet L.; Søholm Hansen, Christine; Spijker, Anne T.; St Clair, David; Steffens, Michael; Strauss, John S.; Streit, Fabian; Strohmaier, Jana; Szelinger, Szabolcs; Thompson, Robert C.; Thorgeirsson, Thorgeir E; Treutlein, Jens; Vedder, Helmut; Wang, Weiqing; Watson, Stanley J.; Weickert, Thomas W.; Witt, Stephanie H.; Xi, Simon; Xu, Wei; Young, Allan H.; Zandi, Peter; Zhang, Peng; Zöllner, Sebastian; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Backlund, Lena; Baune, Bernhard T.; Bellivier, Frank; Berrettini, Wade H.; Biernacka, Joanna M.; Blackwood, Douglas H.R.; Boehnke, Michael; Børglum, Anders D.; Corvin, Aiden; Craddock, Nicholas; Daly, Mark J.; Dannlowski, Udo; Esko, Tõnu; Etain, Bruno; Frye, Mark; Fullerton, Janice M.; Gershon, Elliot S.; Gill, Michael; Goes, Fernando; Grigoroiu-Serbanescu, Maria; Hauser, Joanna; Hougaard, David M.; Hultman, Christina M.; Jones, Ian; Jones, Lisa A.; Kahn, René S.; Kirov, George; Landén, Mikael; Leboyer, Marion; Lewis, Cathryn M.; Li, Qingqin S.; Lissowska, Jolanta; Martin, Nicholas G.; Mayoral, Fermin; McElroy, Susan L.; McIntosh, Andrew M.; McMahon, Francis J.; Melle, Ingrid; Metspalu, Andres; Mitchell, Philip B.; Morken, Gunnar; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Myers, Richard M.; Neale, Benjamin M.; Nimgaonkar, Vishwajit; Nordentoft, Merete; Nöthen, Markus M.; O'Donovan, Michael C; Ødegaard, Ketil Joachim; Owen, Michael J.; Paciga, Sara A.; Pato, Carlos; Pato, Michele T.; Posthuma, Danielle; Ramos-Quiroga, Josep Antoni; Ribasés, Marta; Rietschel, Marcella; Rouleau, Guy A.; Schalling, Martin; Schofield, Peter R.; Schulze, Thomas G.; Serretti, Alessandro; Smoller, Jordan W.; Stefansson, Hreinn; Stefansson, Kari; Stordal, Eystein; Sullivan, Patrick F.; Turecki, Gustavo; Vaaler, Arne; Vieta, Eduard; Vincent, John B.; Werge, Thomas; Nurnberger, John I.; Wray, Naomi R.; Di Florio, Arianna; Edenberg, Howard J.; Cichon, Sven; Ophoff, Roel A.; Scott, Laura J.; Andreassen, Ole Andreas; Kelsoe, John & Sklar, Pamela (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. ISSN 1061-4036. 51(5), s 793- 803 . doi: 10.1038/s41588-019-0397-8
Steen, Nils Eiel; Dieset, Ingrid; Hope, Sigrun; Vedal, Trude Seselie Jahr; Smeland, Olav Bjerkehagen; Matson, Wayne; Kaddurah-Daouk, Rima; Agartz, Ingrid; Melle, Ingrid; Djurovic, Srdjan; Jönsson, Erik Gunnar; Bogdanov, Mikhail & Andreassen, Ole Andreas (2019). Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders. Psychological Medicine. ISSN 0033-2917. 17(2) . doi: 10.1017/S0033291719000400
Storvestre, Guttorm Breivik; Valnes, Lars Magnus; Jensen, Arvid; Nerland, Stener; Tesli, Natalia; Hymer, Knut-Erik; Røsæg, Cato; Server, Andres Alonso; Ringen, Petter Andreas; Jacobsen, Morten; Andreassen, Ole Andreas; Agartz, Ingrid; Melle, Ingrid & Haukvik, Unn Kristin H. (2019). A preliminary study of cortical morphology in schizophrenia patients with a history of violence. Psychiatry Research : Neuroimaging. ISSN 0925-4927. 288, s 29- 36 . doi: 10.1016/j.pscychresns.2019.04.013
Svendsen, Ingrid Hartveit; Øie, Merete Glenne; Møller, Paul; Nelson, Barnaby; Haug, Elisabeth & Melle, Ingrid (2019). Basic Self-Disturbances Independently Predict Recovery in Psychotic Disorders: A Seven Year Follow-up Study. Schizophrenia Research. ISSN 0920-9964.
Tesli, Natalia; Westlye, Lars Tjelta; Storvestre, Guttorm Breivik; Gurholt, Tiril Pedersen; Agartz, Ingrid; Melle, Ingrid; Andreassen, Ole Andreas & Haukvik, Unn Kristin H. (2019). White matter microstructure in schizophrenia patients with a history of violence. European Archives of Psychiatry and Clinical Neuroscience. ISSN 0940-1334. . doi: 10.1007/s00406-019-00988-0
Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen & Jönsson, Erik Gunnar (2019). Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI. Psychoneuroendocrinology. ISSN 0306-4530. 103, s 87- 95 . doi: 10.1016/j.psyneuen.2019.01.001
Aas, Monica; Dieset, Ingrid; Mørch, Ragni Helene; Steen, Nils Eiel; Hope, Sigrun; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Ueland, Thor; Aukrust, Pål; Melle, Ingrid; Agartz, Ingrid & Andreassen, Ole Andreas (2018). Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders. Schizophrenia Research. ISSN 0920-9964. . doi: 10.1016/j.schres.2018.08.007 Full text in Research Archive.
Aas, Monica; Djurovic, Srdjan; Ueland, Torill; Mørch, Ragni Helene; Anderssen, Jannicke Fjæra; Reponen, Elina Johanna; Cattaneo, Annamaria; Steen, Nils Eiel; Agartz, Ingrid; Melle, Ingrid & Andreassen, Ole Andreas (2018). The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders. World Journal of Biological Psychiatry. ISSN 1562-2975. . doi: 10.1080/15622975.2018.1557345
Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina; Falcone, Guido; Gormley, Padhraig; Malik, Rainer; Patsopoulos, Nikolaos A.; Ripke, Stephan; Wei, Zhi; Yu, Dongmei; Lee, Phil H.; Turley, Patrick; Grenier-Boley, Benjamin; Chouraki, Vincent; Kamatani, Yoichiro; Berr, Claudine; Letenneur, Luc; Hannequin, Didler; Amouyel, Philippe; Boland, Anne; Deleuze, Jean-François; Duron, Emmanuelle; Vardarajan, Badri N.; Reitz, Christiane; Goate, Alison M.; Huentelman, Matthew; Kamboh, M. Ilyas; Larson, Eric B.; Rogaeva, Ekaterina; St George-Hyslop, Peter; Hakonarson, Hakon; Kukull, Walter A.; Farrer, Lindsay A.; Barnes, Lisa L.; Beach, Thomas G.; Demirci, F. Yesam; Head, Elizabeth; Hulette, Christine M.; Jicha, Gregory A.; Kauwe, John S.K.; Kaye, Jeffery A.; Leverenz, James B.; Levey, AIlan I.; Lieberman, Andrew P.; Pankratz, Vernon S.; Poon, Wayne W.; Quinn, Joseph F.; Saykin, Andrew J.; Schneider, Lon S.; Smith, Amanda G.; Sonnen, Joshua A.; Stern, Robert A.; Van Deerlin, Vivianna M.; Van Eldik, Linda J.; Harold, Denise; Russo, Giancarlo; Rubinsztein, David C.; Bayer, Anthony; Tsolaki, Magda; Proitsi, Petra; Fox, Nick C.; Hampel, Harald; Owen, Michael J.; Mead, Simon; Passmore, Peter; Morgan, Kevin; Nöthen, Markus M.; Rossor, Martin; Lupton, Michelle K.; Hoffmann, Per; Kornhuber, Johannes; Lawlor, Brian; McQuillin, Andrew; Al-Chalabi, Ammar; Bis, Joshua C; Ruiz, Agustin; Boada, Mercè; Seshadri, Sudha; Beiser, Alexa; Rice, Kenneth; van der Lee, Sven J.; De Jager, Philip L.; Geschwind, Daniel H.; Riemenschneider, Matthias; Riedel-Heller, Steffi; Rotter, Jerome I.; Ransmayr, Gerhard; Hyman, Bradley T.; Cruchaga, Carlos; Alegret, Montserrat; Winsvold, Bendik K S; Palta, Priit; Farh, Kai-How; Cuenca-Leon, Ester; Furlotte, Nicholas; Kurth, Tobias; Ligthart, Lannie; Terwindt, Gisela M.; Freilinger, Tobias; Ran, Caroline; Gordon, Scott D.; Borck, Guntram; Adams, Hieab H.H.; Lehtimäki, Terho; Wedenoja, Juho; Buring, Julie E.; Schürks, Markus; Hrafnsdóttir, Maria; Hottenga, Jouke-Jan; Penninx, Brenda; Artto, Ville; Kaunisto, Mari; Vepsäläinen, Salli; Martin, Nicholas G.; Montgomery, Grant W.; Kurki, Mitja I.; Hämäläinen, Eija; Huang, Hailiang; Huang, Jie; Sandor, Cynthia; Webber, Caleb; Muller-Myhsok, Bertram; Schreiber, Stefan; Salomaa, Veikko; Loehrer, Elizabeth; Göbel, Hartmut; Macaya, Alfons; Pozo-Rosich, Patricia; Hansen, Thomas; Werge, Thomas; Kaprio, Jaakko; Metspalu, Andres; Kubisch, Christian; Ferrari, Michel D.; Belin, Andrea C.; van den Maagdenberg, Arn M.J.M.; Zwart, John-Anker; Boomsma, Dorret; Eriksson, Nicholas; Olesen, Jes; Chasman, Daniel I.; Nyholt, Dale R.; Avbersek, Andreja; Baum, Larry; Berkovic, Samuel; Bradfield, Jonathan; Buono, Russell; Catarino, Claudia B.; Cossette, Patrick; De Jonghe, Peter; Depondt, Chantal; Dlugos, Dennis; Ferraro, Thomas N.; French, Jacqueline; Hjalgrim, Helle; Jamnadas-Khoda, Jennifer; Kälviäinen, Reetta; Kunz, Wolfram S.; Lerche, Holger; Leu, Costin; Lindhout, Dick; Lo, Warren; Lowenstein, Daniel; McCormack, Mark; Møller, Rikke S.; Molloy, Anne; Ng, Ping-Wing; Oliver, Karen; Privitera, Michael; Radtke, Rodney; Ruppert, Ann-Kathrin; Sander, Thomas; Schachter, Steven; Schankin, Christoph; Scheffer, Ingrid; Schoch, Susanne; Sisodiya, Sanjay M.; Smith, Philip; Sperling, Michael; Striano, Pasquale; Surges, Rainer; Thomas, G. Neil; Visscher, Frank; Whelan, Christopher D.; Zara, Federico; Heinzen, Erin L.; Marson, Anthony; Becker, Felicitas; Stroink, Hans; Zimprich, Fritz; Gasser, Thomas; Gibbs, Raphael; Heutink, Peter; Martinez, Maria; Morris, Huw R.; Sharma, Manu; Ryten, Mina; Mok, Kin Y.; Pulit, Sara; Bevan, Steve; Holliday, Elizabeth; Attia, John; Battey, Thomas; Boncoraglio, Giorgio; Thijs, Vincent; Chen, Wei-Min; Mitchell, Braxton; Rothwell, Peter; Sharma, Pankaj; Sudlow, Cathie; Vicente, Astrid; Markus, Hugh; Kourkoulis, Christina; Pera, Joana; Raffeld, Miriam; Silliman, Scott; Perica, Vesna Boraska; Thornton, Laura M.; Huckins, Laura M.; Rayner, N. William; Lewis, Cathryn M.; Gratacos, Monica; Rybakowski, Filip; Keski-Rahkonen, Anna; Raevuori, Anu; Hudson, James I.; Reichborn-Kjennerud, Ted; Monteleone, Palmiero; Karwautz, Andreas; Mannik, Katrin; Baker, Jessica H.; O'Toole, Julie K.; Trace, Sara E.; Davis, Oliver S.P.; Helder, Sietske G.; Ehrlich, Stefan; Herpertz-Dahlmann, Beate; Danner, Unna N.; van Elburg, Annemarie A.; Clementi, Maurizio; Forzan, Monica; Docampo, Elisa; Lissowska, Jolanta; Hauser, Joanna; Tortorella, Alfonso; Maj, Mario; Gonidakis, Fragiskos; Tziouvas, Konstantinos; Papezova, Hana; Yilmaz, Zeynep; Wagner, Gudrun; Cohen-Woods, Sarah; Herms, Stefan; Julia, Antonio; Rabionet, Raquel; Dick, Danielle M.; Ripatti, Samuli; Andreassen, Ole Andreas; Espeseth, Thomas; Lundervold, Astri; Steen, Vidar Martin; Pinto, Dalila; Scherer, Stephen W.; Aschauer, Harald; Schosser, Alexandra; Alfredsson, Lars; Padyukov, Leonid; Halmi, Katherine A.; Mitchell, James; Strober, Michael; Bergen, Andrew W.; Kaye, Walter; Szatkiewicz, Jin Peng; Cormand, Bru; Ramos-Quiroga, Josep Antoni; Sánchez-Mora, Cristina; Ribasés, Marta; Casas, Miguel; Hervas, Amaia; Arranz, Maria Jesús; Haavik, Jan; Zayats, Tetyana; Johansson, Stefan; Williams, Nigel; Dempfle, Astrid; Rothenberger, Aribert; Kuntsi, Jonna; Oades, Robert D.; Banaschewski, Tobias; Franke, Barbara; Buitelaar, Jan K.; Vasquez, Alejandro Arias; Doyle, Alysa E.; Reif, Andreas; Lesch, Klaus-Peter; Freitag, Christine; Rivero, Olga; Palmason, Haukur; Romanos, Marcel; Langley, Kate; Rietschel, Marcella; Witt, Stephanie H.; Dalsgaard, Søren; Børglum, Anders D.; Waldman, Irwin; Wilmot, Beth; Molly, Nikolas; Bau, Claiton Henrique Dotto; Crosbie, Jennifer; Schachar, Russell; Loo, Sandra K.; McGough, James J.; Grevet, Eugenio H.; Medland, Sarah E.; Robinson, Elise; Weiss, Lauren A.; Bacchelli, Elena; Bailey, Anthony; Bal, Vanessa; Battaglia, Agatino; Betancur, Catalina; Bolton, Patrick; Cantor, Rita; Celestino-Soper, Patrícia; Dawson, Geraldine; De Rubeis, Silvia; Duque, Frederico; Green, Andrew; Klauck, Sabine M.; Leboyer, Marion; Levitt, Pat; Maestrini, Elena; Mane, Shrikant; Moreno-De-Luca, Daniel; Parr, Jeremy; Regan, Regina; Reichenberg, Abraham; Sandin, Sven; Vorstman, Jacob; Wassink, Thomas; Wijsman, Ellen; Cook, Edwin; Santangelo, Susan; Delorme, Richard; Rogé, Bernadette; Magalhaes, Tiago; Arking, Dan; Schulze, Thomas G.; Thompson, Robert C.; Strohmaier, Jana; Matthews, Keith; Melle, Ingrid; Morris, Derek; Blackwood, Douglas; McIntosh, Andrew; Bergen, Sarah E.; Schalling, Martin; Jamain, Stéphane; Maaser, Anna; Fischer, Sascha B.; Reinbold, Céline S.; Fullerton, Janice M.; Guzman-Parra, José; Mayoral, Fermin; Schofield, Peter R.; Cichon, Sven; Mühleisen, Thomas W.; Degenhardt, Franziska; Schumacher, Johannes; Bauer, Michael; Mitchell, Philip B.; Gershon, Elliot S.; Rice, John; Potash, James B.; Zandi, Peter P.; Craddock, Nick; Ferrier, I. Nicol; Alda, Martin; Rouleau, Guy A.; Turecki, Gustavo; Ophoff, Roel; Pato, Carlos; Anjorin, Adebayo; Stahl, Eli; Leber, Markus; Czerski, Piotr M.; Cruceanu, Cristiana; Jones, Ian R.; Posthuma, Danielle; Andlauer, Till F.M.; Forstner, Andreas J.; Streit, Fabian; Baune, Bernhard T.; Air, Tracy; Sinnamon, Grant; Wray, Naomi R.; MacIntyre, Donald J.; Porteous, David; Homuth, Georg; Rivera, Margarita; Grove, Jakob; Middeldorp, Christel M.; Hickie, Ian; Pergadia, Michele; Mehta, Divya; Smit, Johannes H.; Jansen, Rick; De Geus, Eco; Dunn, Erin; Li, Qingqin S.; Nauck, Matthias; Schoevers, Robert A.; Beekman, Aartjan T.F.; Knowles, James A.; Viktorin, Alexander; Arnold, Paul; Barr, Cathy L.; Bedoya-Berrio, Gabriel; Bienvenu, O. Joseph; Brentani, Helena; Burton, Christie; Camarena, Beatriz; Cappi, Carolina; Cath, Danielle; Cavallini, Maria; Cusi, Daniele; Darrow, Sabrina; Denys, Damiaan; Derks, Eske M.; Dietrich, Andrea; Fernandez, Thomas; Figee, Martijn; Freimer, Nelson; Gerber, Gloria; Grados, Marco; Greenberg, Erica; Hanna, Gregory L.; Hartmann, Andreas; Hirschtritt, Matthew E.; Hoekstra, Pieter J.; Huang, Alden; Huyser, Chaim; Illmann, Cornelia; Jenike, Michael; Kuperman, Samuel; Leventhal, Bennett; Lochner, Christine; Lyon, Gholson J.; Macciardi, Fabio; Madruga-Garrido, Marcos; Malaty, Irene A.; Maras, Athanasios; McGrath, Lauren; Miguel, Eurípedes C.; Mir, Pablo; Nestadt, Gerald; Nicolini, Humberto; Okun, Michael S.; Pakstis, Andrew; Paschou, Peristera; Piacentini, John; Pittenger, Christopher; Plessen, Kerstin; Ramensky, Vasily; Ramos, Eliana M.; Reus, Victor; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Roessner, Veit; Rosário, Maria; Samuels, Jack F.; Sandor, Paul; Stein, Dan J.; Tsetsos, Fotis; Van Nieuwerburgh, Filip; Weatherall, Sarah; Wendland, Jens R.; Wolanczyk, Tomasz; Worbe, Yulia; Zai, Gwyneth; Goes, Fernando S.; McLaughlin, Nicole; Nestadt, Paul S.; Grabe, Hans-Jörgen; Depienne, Christel; Konkashbaev, Anuar; Lanzagorta, Núria; Valencia-Duarte, Ana; Bramon, Elvira; Buccola, Nancy; Cahn, Wiepke; Cairns, Murray; Chong, Siow A.; Cohen, David; Crespo-Facorro, Benedicto; Crowley, James; Davidson, Michael; DeLisi, Lynn; Dinan, Timothy; Donohoe, Gary; Drapeau, Elodie; Duan, Jubao; Haan, Lieuwe; Hougaard, David; Karachanak-Yankova, Sena; Khrunin, Andrey; Klovins, Janis; Kučinskas, Vaidutis; Keong, Jimmy Lee Chee; Limborska, Svetlana; Loughland, Carmel; Lonnqvist, Jouko; Maher, Brion; Mattheisen, Manuel; McDonald, Colm; Murphy, Kieran C.; Nenadic, Igor; Van Os, Jim; Pantelis, Christos; Pato, Michele; Petryshen, Tracey; Quested, Digby; Roussos, Panos; Sanders, Alan R.; Schall, Ulrich; Schwab, Sibylle G.; Sim, Kang; So, Hon-Cheong; Stogmann, Elisabeth; Subramaniam, Mythily; Toncheva, Draga; Waddington, John; Walters, James; Weiser, Mark; Cheng, Wei; Cloninger, Robert; Curtis, David; Gejman, Pablo V.; Henskens, Frans; Mattingsdal, Morten; Oh, Sang-Yun; Scott, Rodney; Webb, Bradley; Breen, Gerome; Churchhouse, Claire; Bulik, Cynthia M.; Daly, Mark; Dichgans, Martin; Faraone, Stephen V.; Guerreiro, Rita; Holmans, Peter; Kendler, Kenneth S.; Koeleman, Bobby; Mathews, Carol A.; Price, Alkes; Scharf, Jeremiah; Sklar, Pamela; Williams, Julie; Wood, Nicholas W.; Cotsapas, Chris; Palotie, Aarno; Smoller, Jordan W.; Sullivan, Patrick; Rosand, Jonathan; Corvin, Aiden & Neale, Benjamin M. (2018). Analysis of shared heritability in common disorders of the brain. Science. ISSN 0036-8075. 360(6395) . doi: 10.1126/science.aap8757
Berg, Akiah Ottesen; Jørgensen, Kjetil Nordbø; Nerhus, Mari; Athanasiu, Lavinia; Popejoy, Alice; Bettella, Francesco; Norbom, Linn Christin Bonaventure; Gurholt, Tiril Pedersen; Dahl, Sandra Rinne; Andreassen, Ole Andreas; Djurovic, Srdjan; Agartz, Ingrid & Melle, Ingrid (2018). Vitamin D levels, brain volume, and genetic architecture in patients with psychosis. PLoS ONE. ISSN 1932-6203. 13(8) . doi: 10.1371/journal.pone.0200250 Full text in Research Archive.
Bjørnestad, Jone Ravndal; Veseth, Marius; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid & Hegelstad, Wenche (2018). Psychotherapy in psychosis: Experiences of fully recovered service users. Frontiers in Psychology. ISSN 1664-1078. 9, s 1- 7 . doi: 10.3389/fpsyg.2018.01675 Full text in Research Archive.
Büchmann, Camilla Bakkalia; Pedersen, Geir Feigum; Aminoff, Sofie Ragnhild; Anderssen, Jannicke Fjæra; Barrett, Elizabeth Ann; Melle, Ingrid & Lagerberg, Trine Vik (2018). Validity of the Birchwood Insight Scale in patients with schizophrenia spectrum- and bipolar disorders. Psychiatry Research. ISSN 0165-1781. 272, s 715- 722 . doi: 10.1016/j.psychres.2018.12.072 Show summary
The aim of this study is to investigate the validity of the Norwegian version of the Insight Scale (IS) in large and representative samples of patients with schizophrenia spectrum disorders, bipolar I disorder and bipolar II disorder. A total of 997 participants were included (schizophrenia spectrum disorders: 557; bipolar I disorder: 282; bipolar II disorder: 138). Confirmatory factor analysis was conducted to investigate the construct validity and bivariate correlational analysis was applied to investigate convergent validity. Confirmatory factor analyses indicated a reasonable model fit to the original three-factor subscale structure of the IS in all three diagnostic groups. The IS total score and its subscales correlated significantly with both the insight items in the Young Mania Rating Scale and the Positive and Negative Syndrome Scale in both schizophrenia spectrum disorders and bipolar I disorder. In the bipolar II disorder group, however, the IS subscales correlated poorly with both the observer-rated measures. Our study supports the construct validity of the IS in both schizophrenia spectrum disorder- and bipolar disorder populations. The study also demonstrates that patients’ self-reports of insight correspond to observer-based single item ratings of insight in bipolar I disorder and schizophrenia spectrum disorders.
Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David; Hagenaars, Saskia P.; Ritchie, Stuart J.; Marioni, Riccardo E.; Fawns-Ritchie, Chloe; Liewald, David C.M.; Okely, Judith A.; Ahola-Olli, Ari V.; Barnes, Catriona L.K.; Bertram, Lars; Bis, Joshua C.; Burdick, Katherine E.; Derosse, Pamela; Djurovic, Srdjan; Espeseth, Thomas; Giakoumaki, Stella; Giddaluru, Sudheer; Gustavson, Daniel E.; Hayward, Caroline; Hofer, Edith; Ikram, M. Arfan; Karlsson, Robert; Knowles, Emma; Lahti, Jari; Leber, Markus; Li, Shuo; Mather, Karen A.; Melle, Ingrid; Morris, Derek; Oldmeadow, Christopher; Palviainen, Teemu; Payton, Antony; Pazoki, Raha; Petrovic, Katja; Reynolds, Chandra A.; Sargurupremraj, Muralidharan; Scholz, Markus; Smith, Jennifer A.; Smith, Albert V.; Terzikhan, Natalie; Thalamuthu, Anbupalam; Trompet, Stella; van der Lee, Sven J.; Ware, Erin B.; Windham, B. Gwen; Wright, Margaret J.; Yang, Jingyun; Yu, Jin; Ames, David; Amin, Najaf; Amouyel, Philippe; Andreassen, Ole Andreas; Armstrong, Nicola J.; Assareh, Amelia A; Attia, John R.; Attix, Deborah; Avramopoulos, Dimitrios; Bennett, David A.; Böhmer, Anne C.; Boyle, Patricia A.; Brodaty, Henry; Campbell, Harry; Cannon, Tyrone D.; Cirulli, Elizabeth T.; Congdon, Eliza; Conley, Emily Drabant; Corley, Janie; Cox, Simon R.; Dale, Anders; Dehghan, Abbas; Dick, Danielle; Dickinson, Dwight; Eriksson, Johan G.; Evangelou, Evangelos; Faul, Jessica D.; Ford, Ian; Freimer, Nelson A.; Gao, He; Giegling, Ina; Gillespie, Nathan A.; Gordon, Scott D.; Gottesman, Rebecca F.; Griswold, Michael E.; Gudnason, Vilmundur; Harris, Tamara B.; Hartmann, Annette M.; Hatzimanolis, Alex; Heiss, Gerardo; Holliday, Elizabeth G.; Joshi, Peter K.; Kähönen, Mika; Kardia, Sharon L.R.; Karlsson, Ida; Kleineidam, Luca; Knopman, David S.; Kochan, Nicole A.; Konte, Bettina; Kwok, John B.; Le Hellard, Stephanie; Lee, Teresa; Lehtimäki, Terho; Li, Shu-Chen; Liu, Tian; Koini, Marisa; London, Edythe; Longstreth, Will T.; Lopez, Oscar L.; Loukola, Anu; Luck, Tobias; Lundervold, Astri; Lundquist, Anders; Lyytikäinen, Leo-Pekka; Martin, Nicholas G.; Montgomery, Grant W.; Murray, Alison D.; Need, Anna C.; Noordam, Raymond; Nyberg, Lars; Ollier, William; Papenberg, Göran; Pattie, Alison; Polasek, Ozren; Poldrack, Russell A.; Psaty, Bruce M.; Reppermund, Simone; Riedel-Heller, Steffi G.; Rose, Richard J.; Rotter, Jerome I.; Roussos, Panos; Rovio, Suvi P.; Saba, Yasaman; Sabb, Fred W.; Sachdev, Perminder S.; Satizabal, Claudia L.; Schmid, Matthias; Scott, Rodney J.; Scult, Matthew A.; Simino, Jeannette; Slagboom, P. Eline; Smyrnis, Nikolaos; Soumaré, Aïcha; Stefanis, Nikos C.; Stott, David J.; Straub, Richard E.; Sundet, Kjetil Søren; Taylor, Adele M.; Taylor, Kent D.; Tzoulaki, Ioanna; Tzourio, Christophe; Uitterlinden, André; Vitart, Veronique; Voineskos, Aristotle N.; Kaprio, Jaakko; Wagner, Michael; Wagner, Holger; Weinhold, Leonie; Wen, K. Hoyan; Widén, Elisabeth; Yang, Qiong; Zhao, Wei; Adams, Hieab H.H.; Arking, Dan E.; Bilder, Robert M.; Bitsios, Panos; Boerwinkle, Eric; Chiba-Falek, Ornit; Christoforou, Andrea; Corvin, Aiden; De Jager, Philip L.; Debette, Stéphanie; Donohoe, Gary; Elliott, Paul; Fitzpatrick, Annette L.; Gill, Michael; Glahn, David C.; Hägg, Sara; Hansell, Narelle K.; Hariri, Ahmad; Ikram, M. Kamran; Jukema, J. Wouter; Vuoksimaa, Eero; Keller, Matthew C.; Kremen, William S.; Launer, Lenore; Lindenberger, Ulman; Palotie, Aarno; Pedersen, Nancy L.; Pendleton, Neil; Porteous, David J.; Räikkönen, Katri; Raitakari, Olli T.; Ramirez, Alfredo; Reinvang, Ivar; Rudan, Igor; Rujescu, Dan; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter W.; Schofield, Peter R.; Starr, John M.; Steen, Vidar Martin; Trollor, Julian N.; Turner, Steven T.; Van Duijn, Cornelia M.; Villringer, Arno; Weinberger, Daniel R.; Weir, David R.; Wilson, James F.; Malhotra, Anil; McIntosh, Andrew M.; Gale, Catharine R.; Seshadri, Sudha; Mosley, Thomas H.; Bressler, Jan; Lencz, Todd & Deary, Ian J. (2018). Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. ISSN 2041-1723. 9(2098), s 1- 16 . doi: 10.1038/s41467-018-04362-x Full text in Research Archive.
de Jong, Simone; Diniz, Mateus Jose Abdalla; Saloma, Andiara; Gadelha, Ary; Santoro, Marcos L.; Ota, Vanessa K.; Noto, Cristiano; Thompson, Wesley Kurt; Wang, Yunpeng; Djurovic, Srdjan; Melle, Ingrid; Morken, Gunnar; Andreassen, Ole Andreas; Mattingsdal, Morten; Curtis, Charles; Newhouse, Stephen J.; Patel, Hamel; Hall, Lynsey S.; O`Reilly, Paul F.; Belangero, Sintia I.; Bressan, Rodrigo A. & Breen, Gerome (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology. ISSN 2399-3642. 1(163) . doi: 10.1038/s42003-018-0155-y Full text in Research Archive.
Demmo, Christine; Lagerberg, Trine Vik; Kvitland, Levi Røstad; Aminoff, Sofie Ragnhild; Hellvin, Tone; Simonsen, Carmen Elisabeth; Haatveit, Beathe Almenning; Andreassen, Ole Andreas; Melle, Ingrid & Ueland, Torill (2018). Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study. Bipolar Disorders. ISSN 1398-5647. 20(3), s 228- 237 . doi: 10.1111/bdi.12569 Show summary
OBJECTIVES: Due to limited research on the association between recurrence of mood episodes and the longitudinal course of neurocognitive functioning in early phase bipolar I disorder (BD I), the impact of recurrence on neurocognition remains unclear. Further, a strong correlation between neurocognitive impairment and functional impairment has been demonstrated. The longitudinal relationship between neurocognitive impairment and functional outcome in relation to recurrence is, however, not established. METHODS: The current study investigated the longitudinal relationship between neurocognition, recurrence of mood episodes and functional outcome in a sample of first-treatment (FT) BD I patients (N = 42), with and without relapse, during a 1-year follow-up period. The longitudinal course of neurocognitive functioning in the patients was also compared to that of a group of healthy controls (N = 143). RESULTS: Compared to both patients with relapse and healthy controls, no-relapse patients showed neurocognitive improvements. The polarity of the relapse episodes was mostly depressive, and for the no-relapse patients, reduction of symptoms was associated with neurocognitive improvement. No-relapse patients showed better global and occupational functioning. CONCLUSIONS: The current study found different neurocognitive and functional trajectories in FT BD I patients with and without relapse, with differences at follow-up to some degree being mediated by current symptoms. The current findings highlight the importance of treatment focusing on neurocognition and symptom states with the aim of improving functional recovery.
Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Reponen, Elina Johanna; Gran, Jon Michael; Aas, Monica; Michelsen, Annika; Reichborn-Kjennerud, Ted; Nesvåg, Ragnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Torill & Andreassen, Ole Andreas (2018). An association between YKL-40 and type 2 diabetes in psychotic disorders. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 139, s 37- 45 . doi: 10.1111/acps.12971
Færden, Ann; Lyngstad, Siv Hege; Simonsen, Carmen Elisabeth; Ringen, Petter Andreas; Papsuev, Oleg; Dieset, Ingrid; Andreassen, Ole Andreas; Agartz, Ingrid; Marder, Stephen R. & Melle, Ingrid (2018). Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up. Psychiatry Research. ISSN 0165-1781. 267, s 140- 147 . doi: 10.1016/j.psychres.2018.05.065
Gardsjord, Erlend Strand; Romm, Kristin Lie; Røssberg, Jan Ivar; Friis, Svein; Barder, Helene; Evensen, Julie Horgen; Haahr, Ulrik; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes H.; Larsen, Tor Ketil; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per Jørgen Wiggen & Melle, Ingrid (2018). Depression and functioning are important to subjective quality of life after a first episode psychosis. Comprehensive Psychiatry. ISSN 0010-440X. 86, s 107- 114 . doi: 10.1016/j.comppsych.2018.07.014
Gjerde, Priyanthi Borgen; Dieset, Ingrid; Simonsen, Carmen Elisabeth; Hoseth, Eva Zsuzsanna; Iversen, Trude Seselie Jahr; Lagerberg, Trine Vik; Lyngstad, Siv Hege; Mørch, Ragni Helene; Skrede, Silje; Andreassen, Ole Andreas; Melle, Ingrid & Steen, Vidar Martin (2018). Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis. Schizophrenia Research. ISSN 0920-9964. 197, s 253- 260 . doi: 10.1016/j.schres.2017.10.042 Full text in Research Archive. Show summary
Background A potential link between increase in total cholesterol and triglycerides and clinical improvement has been observed during antipsychotic drug treatment in chronic schizophrenia patients, possibly due to drug related effects on lipid biosynthesis. We examined whether changes in serum lipids are associated with alleviation of psychosis symptoms after one year of antipsychotic drug treatment in a cohort of first-episode psychosis (FEP) patients. Methods A total of 132 non-affective antipsychotic-treated FEP patients were included through the Norwegian Thematically Organized Psychosis (TOP) project. Data on antipsychotic usage, serum lipids (total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol and triglycerides (TG)), body mass index (BMI) and clinical state were obtained at baseline and after 12 months. The Positive and Negative Syndrome Scale (PANSS) was used to assess psychotic symptoms. Mixed-effects models were employed to examine the relationship between serum lipids and psychotic symptoms while controlling for potential confounders including BMI. Results An increase in HDL during one year of antipsychotic treatment was associated with reduction in PANSS negative subscores (B = − 0.48, p = 0.03). This relationship was not affected by concurrent change in BMI (adjusted HDL: B = − 0.54, p = 0.02). No significant associations were found between serum lipids, BMI and PANSS positive subscores. Conclusion We found that an increase in HDL level during antipsychotic treatment is associated with improvement in negative symptoms in FEP. These findings warrant further investigation to clarify the interaction between lipid pathways and psychosis.
Gjerde, Priyanthi Borgen; Jørgensen, Kjetil Nordbø; Steen, Nils Eiel; Melle, Ingrid; Andreassen, Ole Andreas; Steen, Vidar Martin & Agartz, Ingrid (2018). Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders. Psychiatry Research : Neuroimaging. ISSN 0925-4927. 282, s 55- 63 . doi: 10.1016/j.pscychresns.2018.10.001
Gohar, Sherif Mostafa Mohamed Ahmed; Dieset, Ingrid; Steen, Nils Eiel; Mørch, Ragni Helene; Vedal, Trude Seselie Jahr; Steen, Vidar Martin; Andreassen, Ole Andreas & Melle, Ingrid (2018). Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders.. European Archives of Psychiatry and Clinical Neuroscience. ISSN 0940-1334. . doi: 10.1007/s00406-018-0897-z Full text in Research Archive.
Gurholt, Tiril Pedersen; Osnes, Kåre; Nerhus, Mari; Jørgensen, Kjetil Nordbø; Lonning, Vera Louise Hiorth; Berg, Akiah Ottesen; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2018). Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls. Scientific Reports. ISSN 2045-2322. 8 . doi: 10.1038/s41598-018-29141-y Full text in Research Archive.
Hartberg, Cecilie Bhandari; Lange, Elisabeth Heffermehl; Lagerberg, Trine Vik; Haukvik, Unn Kristin H.; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2018). Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use. European Neuropsychopharmacology. ISSN 0924-977X. 28(1), s 37- 47 . doi: 10.1016/j.euroneuro.2017.11.019
Hoseth, Eva Zsuzsanna; Krull, Florian; Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Gardsjord, Erlend Strand; Steen, Nils Eiel; Melle, Ingrid; Brattbakk, Hans-Richard; Steen, Vidar Martin; Aukrust, Pål; Djurovic, Srdjan; Andreassen, Ole Andreas & Ueland, Thor (2018). Attenuated Notch signaling in schizophrenia and bipolar disorder. Scientific Reports. ISSN 2045-2322. 8:5349, s 1- 8 . doi: 10.1038/s41598-018-23703-w Full text in Research Archive.
Hoseth, Eva Zsuzsanna; Krull, Florian; Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Gardsjord, Erlend Strand; Steen, Nils Eiel; Melle, Ingrid; Brattbakk, Hans-Richard; Steen, Vidar Martin; Aukrust, Pål; Djurovic, Srdjan; Andreassen, Ole Andreas & Ueland, Thor (2018). Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder. Translational psychiatry. ISSN 2158-3188. 8:55, s 1- 10 . doi: 10.1038/s41398-018-0102-1 Full text in Research Archive.
Iversen, Trude Seselie Jahr; Steen, Nils Eiel; Dieset, Ingrid; Hope, Sigrun; Mørch, Ragni Helene; Gardsjord, Erlend Strand; Jørgensen, Kjetil Nordbø; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen & Jönsson, Erik Gunnar (2018). Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy. Progress in Neuro-psychopharmacology and Biological Psychiatry. ISSN 0278-5846. 82, s 263- 271 . doi: 10.1016/j.pnpbp.2017.11.004
Lyngstad, Siv Hege; Gardsjord, Erlend Strand; Simonsen, Carmen Elisabeth; Engen, Magnus Johan; Romm, Kristin Lie; Melle, Ingrid & Færden, Ann (2018). Consequences of persistent depression and apathy in first-episode psychosis ? A one-year follow-up study. Comprehensive Psychiatry. ISSN 0010-440X. 86, s 60- 66 . doi: 10.1016/j.comppsych.2018.07.015
Maier, Robert M.; Zhu, Zhihong; Lee, Sang Hong; Trzaskowski, Maciej; Ruderfer, Douglas M.; Stahl, Eli A.; Ripke, Stephan; Wray, Naomi R.; Yang, Jian; Visscher, Peter M.; Robinson, Matthew R.; Wang, Yunpeng; Elvsåshagen, Torbjørn; Djurovic, Srdjan; Agartz, Ingrid; Mattingsdal, Morten & Melle, Ingrid (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications. ISSN 2041-1723. 9:989, s 1- 17 . doi: 10.1038/s41467-017-02769-6
Mørch-Johnsen, Lynn; Nerland, Stener; Jørgensen, Kjetil Nordbø; Osnes, Kåre; Hartberg, Cecilie Bhandari; Andreassen, Ole Andreas; Melle, Ingrid; Nesvåg, Ragnar & Agartz, Ingrid (2018). Cortical thickness abnormalities in bipolar disorder patients with a lifetime history of auditory hallucinations. Bipolar Disorders. ISSN 1398-5647. 20(7), s 647- 657 . doi: 10.1111/bdi.12627
Ni, Guiyan; Gratten, Jacob; Wray, Naomi R.; Lee, Sang Hong; Agartz, Ingrid; Djurovic, Srdjan; Joa, Inge; Mattingsdal, Morten; Melle, Ingrid; Andreassen, Ole Andreas & Jönsson, Erik Gunnar (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports. ISSN 2045-2322. 8 . doi: 10.1038/s41598-018-28160-z
Psychiatric Genomics Consorti, Bipolar Sczhizophrenia; Ruderfer, Douglas M.; Ripke, Stephan; McQuillin, Andrew; Boocock, James; Stahl, Eli A.; Pavlides, Jennifer M. Whitehead; Mullins, Niamh; Charney, Alxander W.; Ori, Anil P.S.; Domenici, Enrico; Di Florio, A; Papiol, S; Kalman, Janos; Adolfsson, Rolf; Agartz, Ingrid; Agerbo, Esben; Akil, Huda; Djurovic, Srdjan; Elvsåshagen, Torbjørn; Joa, Inge; Malt, Ulrik Fredrik; Mattingsdal, Morten; Melle, Ingrid; Morken, Gunnar; Nordentoft, Merete; Nordin, Annelie; Ødegaard, Ketil Joachim; Smeland, Olav Bjerkehagen; Stordal, Eystein; Vaaler, Arne; Wang, Yunpeng; Zheng, Xuebin; Zimprich, Fritz; Zöllner, Sebastian; Corvin, Aiden; Fanous, Ayman H.; Rietschel, Marcella; Gershon, Elliot S.; Schulze, Thomas G.; Cuellar-Barboza, Alfredo B.; Forstner, Andreas J.; Holmans, Peter A.; Nurnberger, John I.; Andreassen, Ole Andreas; Hong Lee, S; O'Donovan, Michael C.; Sullivan, Patrick F.; Ophoff, Roel A.; Wray, Naomi R.; Sklar, Pamela & Kendler, Kenneth S. (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.. Cell. ISSN 0092-8674. 173(7), s 1705- 1715 . doi: 10.1016/j.cell.2018.05.046
Savage, Jeanne E.; Jansen, Philip R.; Stringer, Sven; Watanabe, Kyoko; Bryois, Julien; de Leeuw, Christiaan A.; Nagel, Mats; Awasthi, Swapnil; Barr, Peter B.; Coleman, Jonathan R.I.; Grasby, Katrina L.; Hammerschlag, Anke R.; Kaminski, Jakob A.; Karlsson, Robert; Krapohl, Eva; Lam, Max; Nygaard, Marianne; Reynolds, Chandra A.; Trampush, Joey W.; Young, Hannah; Zabaneh, Delilah; Hägg, Sara; Hansell, Narelle K.; Karlsson, Ida K.; Linnarsson, Sten; Montgomery, Grant W.; Muñoz-Manchado, Ana B.; Quinlan, Erin B.; Schumann, Gunter; Skene, Nathan G.; Webb, Bradley T.; White, Tonya; Arking, Dan E.; Avramopoulos, Dimitrios; Bilder, Robert M.; Bitsios, Panos; Burdick, Katherine E.; Cannon, Tyrone D.; Chiba-Falek, Ornit; Christoforou, Andrea; Cirulli, Elizabeth T.; Congdon, Eliza; Corvin, Aiden; Davies, Gail; Deary, Ian J.; DeRosse, Pamela; Dickinson, Dwight; Djurovic, Srdjan; Donohoe, Gary; Conley, Emily Drabant; Eriksson, Johan G.; Espeseth, Thomas; Freimer, Nelson A.; Giakoumaki, Stella; Giegling, Ina; Gill, Michael; Glahn, David C.; Hariri, Ahmad; Hatzimanolis, Alex; Keller, Matthew C.; Knowles, Emma; Koltai, Deborah; Konte, Bettina; Lahti, Jari; Le Hellard, Stephanie; Lencz, Todd; Liewald, David C.; London, Edythe; Lundervold, Astri; Malhotra, Anil K.; Melle, Ingrid; Morris, Derek; Need, Anna C.; Ollier, William; Palotie, Aarno; Payton, Antony; Pendleton, Neil; Poldrack, Russell A.; Räikkönen, Katri; Reinvang, Ivar; Roussos, Panos; Rujescu, Dan; Sabb, Fred W.; Scult, Matthew A; Smeland, Olav Bjerkehagen; Smyrnis, Nikolaos; Starr, John M; Steen, Vidar Martin; Stefanis, Nikos C.; Straub, Richard E.; Sundet, Kjetil Søren; Tiemeier, Henning; Voineskos, Aristotle N.; Weinberger, Daniel R.; Widén, Elisabeth; Yu, Jin; Abecasis, Goncalo; Andreassen, Ole Andreas; Breen, Gerome; Christiansen, Lene; Debrabant, Birgit; Dick, Danielle M.; Heinz, Andreas; Hjerling-Leffler, Jens; Ikram, M. Arfan; Kendler, Kenneth S.; Martin, Nicholas G.; Medland, Sarah E.; Pedersen, Nancy L.; Plomin, Robert; Polderman, Tinca J.C.; Ripke, Stephan; van der Sluis, Sophie; Sullivan, Patrick F.; Vrieze, Scott I; Wright, Margaret J. & Posthuma, Daniëlle (2018). Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. ISSN 1061-4036. 50, s 912- 919 . doi: 10.1038/s41588-018-0152-6
Simonsen, Carmen Elisabeth; Færden, Ann; Ueland, Torill; Vaskinn, Anja; Bjella, Thomas; Andreassen, Ole Andreas; Romm, Kristin Lie & Melle, Ingrid (2018). Self-rated disability in first treated episode of psychosis: A 1-year follow-up study. Comprehensive Psychiatry. ISSN 0010-440X. 85, s 48- 54 . doi: 10.1016/j.comppsych.2018.06.004
Srinivasan, Saurabh; Bettella, Francesco; Frei, Oleksandr; Hill, W. David; Wang, Yunpeng; Witoelar, Aree; Schork, Andrew J.; Thompson, Wesley Kurt; Davies, Gail; Desikan, Rahul S.; Deary, Ian J.; Melle, Ingrid; Ueland, Torill; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen & Andreassen, Ole Andreas (2018). Enrichment of genetic markers of recent human evolution in educational and cognitive traits. Scientific Reports. ISSN 2045-2322. 8:12585, s 1- 9 . doi: 10.1038/s41598-018-30387-9 Full text in Research Archive.
Svendsen, Ingrid Hartveit; Øie, Merete Glenne; Møller, Paul; Nelson, Barnaby; Melle, Ingrid & Haug, Elisabeth (2018). Stability in basic self-disturbances and diagnosis in a first treated psychosis: A seven year follow-up study. Schizophrenia Research. ISSN 0920-9964. 202, s 274- 280 . doi: 10.1016/j.schres.2018.07.011
van der Meer, Dennis; Rokicki, Jaroslav; Kaufmann, Tobias; Còrdova Palomera, Aldo; Moberget, Torgeir; Alnæs, Dag; Bettella, Francesco; Frei, Oleksandr; Doan, Nhat Trung; Sønderby, Ida Elken; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Bertolino, Alessandro; Bralten, Janita; Brandt, Christine Lycke; Buitelaar, Jan K.; Djurovic, Srdjan; van Donkelaar, Marjolein; Dørum, Erlend Solberg; Espeseth, Thomas; Faraone, Stephen V.; Fernandéz, Guillén; Fisher, Simon E.; Franke, Barbara; Haatveit, Beathe Christin; Hartman, Catharina A.; Hoekstra, Pieter J.; Håberg, Asta; Jönsson, Erik Gunnar; Kolskår, Knut-Kristian; Le Hellard, Stephanie; Lund, Martina Jonette; Lundervold, Astri; Lundervold, Arvid; Melle, Ingrid; Monereo Sanchez, Jennifer; Norbom, Linn Christin Bonaventure; Nordvik, Jan Egil; Nyberg, Lars; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pergola, Giulio; de Quervain, Dominique J.F.; Richard, Geneviéve´; Sanders, Anne-Marthe; Selvaggi, Pierluigi; Shumskaya, Elena; Steen, Vidar Martin; Tønnesen, Siren; Ulrichsen, Kristine Moe; Zwiers, Marcel P.; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2018). Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry. ISSN 1359-4184. s 1- 13 . doi: 10.1038/s41380-018-0262-7 Full text in Research Archive.
Van Erp, Theo G.M.; Walton, Esther; Hibar, Derrek; Schmaal, Lianne; Jiang, Wenhao; Glahn, David C.; Pearlson, Godfrey D.; Yao, Nailin; Fukunaga, Masaki; Hashimoto, Ryota; Okada, Naohiro; Yamamori, Hidenaga; Bustillo, Juan R.; Clark, Vincent P.; Agartz, Ingrid; Mueller, Bryon A.; Cahn, Wiepke; de Zwarte, Sonja M.C.; Hulshoff Pol, Hilleke E.; Kahn, René S.; Ophoff, Roel A.; van Haren, Neeltje E.M.; Andreassen, Ole Andreas; Dale, Anders; Doan, Nhat Trung; Gurholt, Tiril Pedersen; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Jørgensen, Kjetil Nordbø; Lagerberg, Trine Vik; Melle, Ingrid; Westlye, Lars Tjelta; Gruber, Oliver; Kraemer, Bernd; Richter, Anja; Zilles, David; Calhoun, Vince D.; Crespo-Facorro, Benedicto; Roiz-Santiañez, Roberto; Tordesillas-Gutiérrez, Diana; Loughland, Carmel; Carr, Vaughan J.; Catts, Stanley; Cropley, Vanessa L.; Fullerton, Janice M.; Green, Melissa J.; Henskens, Frans A.; Jablensky, Assen; Lenroot, Rhoshel K.; Mowry, Bryan J.; Michie, Patricia T.; Pantelis, Christos; Quide, Yann; Schall, Ulrich; Scott, Rodney J.; Cairns, Murray J.; Seal, Marc; Tooney, Paul A.; Rasser, Paul E.; Cooper, Gavin; Shannon Weickert, Cynthia; Weickert, Thomas W.; Morris, Derek W.; Hong, Elliot; Kochunov, Peter; Beard, Lauren M.; Gur, Raquel E.; Gur, Ruben C.; Satterthwaite, Theodore D; Wolf, Daniel H.; Belger, Aysenil; Brown, Gregory G.; Ford, Judith M.; Macciardi, Fabio; Mathalon, Daniel H.; O'Leary, Daniel S.; Potkin, Steven G.; Preda, Adrian; Voyvodic, James; Lim, Kelvin O.; McEwen, Sarah; Yang, Fude; Tan, Yunlong; Tan, Shuping; Wang, Zhiren; Fan, Fengmei; Chen, Jingxu; Xiang, Hong; Tang, Shiyou; Guo, Hua; Wan, Ping; Wei, Dong; Bockholt, Henry J.; Ehrlich, Stefan; Wolthusen, Rick P.F.; King, Margaret D.; Shoemaker, Jody M.; Sponheim, Scott R.; De Haan, Lieuwe; Koenders, Laura; Machielsen, Marise W.; van Amelsvoort, Therese; Veltman, Dick J.; Assogna, Francesca; Banaj, Nerisa; de Rossi, Pietro; Iorio, Mariangela; Piras, Fabrizio; Spalletta, Gianfranco; McKenna, Peter J.; Pomarol-Clotet, Edith; Salvador, Raymond; Corvin, Aiden; Donohoe, Gary; Kelly, Sinead; Whelan, Christopher D.; Dickie, Erin W.; Rotenberg, David; Voineskos, Aristotle N.; Ciufolini, Simone; Radua, Joaquim; Dazzan, Paola; Murray, Robin; Reis Marques, Tiago; Simmons, Andrew; Borgwardt, Stefan; Egloff, Laura; Harrisberger, Fabienne; Riecher-Rössler, Anita; Smieskova, Renata; Alpert, Kathryn I.; Wang, Lei; Jönsson, Erik Gunnar; Koops, Sanne; Sommer, Iris Else Clara; Bertolino, Alessandro; Bonvino, Aurora; Di Giorgio, Annabella; Neilson, Emma; Mayer, Andrew R.; Stephen, Julia M.; Kwon, Jun Soo; Yun, Je-Yeon; Cannon, Dara M.; McDonald, Colm; Lebedeva, Irina; Tomyshev, Alexander S.; Akhadov, Tolibjohn; Kaleda, Vasily; Fatouros-Bergman, Helena & Flyckt, Lena (2018). Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry. ISSN 0006-3223. . doi: 10.1016/j.biopsych.2018.04.023 Full text in Research Archive.
Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen & Jönsson, Erik Gunnar (2018). Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication. Journal of Psychiatric Research. ISSN 0022-3956. 106, s 74- 81 . doi: 10.1016/j.jpsychires.2018.09.014
Walton, E; Hibar, Derrek; Van Erp, Theo G M; Potkin, Steven G; Roiz-Santiañez, Roberto; Crespo-Facorro, B; Suarez-Pinilla, Paula; van Haren, Neeltje E.M.; de Zwarte, Sonja M.C.; Kahn, René S; Cahn, Wiepke; Doan, Nhat Trung; Jørgensen, Kjetil Nordbø; Gurholt, Tiril Pedersen; Agartz, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta; Melle, Ingrid; Berg, Akiah Ottesen; Mørch-Johnsen, Lynn Egeland; Færden, Ann; Flyckt, Lena; Fatouros-Bergman, Helena; Jönsson, Erik Gunnar; Hashimoto, Ryota; Yamamori, Hidenaga; Fukunaga, Masaki; Jahanshad, Neda; De Rossi, Pietro; Piras, Fabrizio; Banaj, Nerisa; Spalletta, Gianfranco; Gur, Raquel E; Gur, Ruben C; Wolf, Daniel H.; Satterthwaite, TD; Beard, Lauren M.; Sommer, Iris E; Koops, Sanne; Gruber, Oliver; Richter, A; Krämer, Bernhard; Kelly, S; Donohoe, G; McDonald, C; Cannon, Dara M; Corvin, Aiden; Gill, M; Di Giorgio, Annabella; Bertolino, A; Lawrie, Stephen M; Nickson, Thomas; Whalley, Heather Clare; Neilson, Emma; Calhoun, Vince D.; Thompson, Paul Murray; Turner, J A & Ehrlich, S (2018). Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium. Psychological Medicine. ISSN 0033-2917. 48(1), s 82- 94 . doi: 10.1017/S0033291717001283 Full text in Research Archive.
Wolfers, Thomas; Doan, Nhat Trung; Kaufmann, Tobias; Alnæs, Dag; Moberget, Torgeir; Agartz, Ingrid; Buitelaar, Jan K.; Ueland, Torill; Melle, Ingrid; Franke, Barbara; Andreassen, Ole Andreas; Beckmann, Christian F.; Westlye, Lars Tjelta & Marquand, André F. (2018). Mapping the heterogeneous phenotype of schizophrenia and bipolar disorder using normative models. JAMA psychiatry. ISSN 2168-622X. 75(11), s 1146- 1155 . doi: 10.1001/jamapsychiatry.2018.2467
Aas, Monica; Dieset, Ingrid; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Mørch, Ragni Helene; Reponen, Elina Johanna; Steen, Nils Eiel; Anderssen, Jannicke Fjæra; Ueland, Thor; Aukrust, Pål; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2017). Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses. Brain, behavior, and immunity. ISSN 0889-1591. 65, s 342- 349 . doi: 10.1016/j.bbi.2017.06.005 Full text in Research Archive.
Aas, Monica; Henry, C.; Bellivier, F; Lajnef, M; Gard, S; Kahn, J-P; Lagerberg, Trine Vik; Aminoff, Sofie Ragnhild; Bjella, Thomas; Leboyer, M; Andreassen, Ole Andreas; Melle, Ingrid & Etain, B (2017). Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders. Psychological Medicine. ISSN 0033-2917. 47(5), s 902- 912 . doi: 10.1017/S0033291716003081
Aas, Monica; Kauppi, Karolina; Brandt, Christine Lycke; Tesli, Martin Steen; Kaufmann, Tobias; Steen, Nils Eiel; Agartz, Ingrid; Westlye, Lars Tjelta; Andreassen, Ole Andreas & Melle, Ingrid (2017). Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders. Psychological Medicine. ISSN 0033-2917. 47(4), s 669- 679 . doi: 10.1017/S0033291716002762
Aas, Monica; Melle, Ingrid; Bettella, Francesco; Djurovic, Srdjan; Le Hellard, Stephanie; Bjella, Thomas; Ringen, Petter Andreas; Lagerberg, Trine Vik; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Andreassen, Ole Andreas & Tesli, Martin Steen (2017). Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not. Psychological Medicine. ISSN 0033-2917. 48(1), s 43- 49 . doi: 10.1017/S0033291717001209 Full text in Research Archive.
Aleman, André; Lincoln, Tania M.; Bruggeman, Richard; Melle, Ingrid; Arends, Johan; Arango, Celso & Knegtering, Henderikus (2017). Treatment of negative symptoms: Where do we stand, and where do we go?. Schizophrenia Research. ISSN 0920-9964. 186, s 55- 62 . doi: 10.1016/j.schres.2016.05.015
Bauer, Michael; Glenn, T; Alda, M; Aleksandrovich, MA; Andreassen, Ole Andreas; Angelopoulos, E; Ardau, R; Ayhan, Y; Baethge, C; Bharathram, SR; Bauer, R; Baune, BT; Becerra-Palars, C; Bellivier, F; Belmaker, RH; Berk, M; Bersudsky, Y; Bicakci, Ş; Birabwa-Oketcho, H; Bjella, Thomas; Bossini, L; Cabrera, J; Cheung, EYW; Del Zompo, M; Dodd, S; Donix, M; Etain, B; Fagiolini, A; Fountoulakis, KN; Frye, MA; Gonzalez-Pinto, A; Gottlieb, JF; Grof, P; Harima, H; Henry, C; Isometsa, ET; Janno, S; Kapczinski, F; Kardell, M; Khaldi, S; Kliwicki, S; König, B; Kot, TL; Krogh, R; Kunz, M; Lafer, B; Landen, M; Larsen, ER; Lewitzka, U; Licht, RW; Lopez-Jaramillo, C; MacQueen, G; Manchia, M; Marsh, W; Martinez-Cengotitabengoa, M; Melle, Ingrid; Meza-Urzua, F; Yee Ming, M; Monteith, S; Morken, Gunnar; Mosca, E; Munoz, R; Mythri, SV; Nacef, F; Nadella, RK; Nery, FG; Nielsen, RE; O'Donovan, C; Omrani, A; Osher, Y; Østermark Sørensen, H; Ouali, U; Pica Ruiz, Y; Pilhatsch, M; Pinna, M; da Ponte, FDR; Quiroz, D; Ramesar, R; Rasgon, N; Reddy, MS; Reif, A; Ritter, P; Rybakowski, JK; Sagduyu, K; Scippa, ÂM; Severus, E; Simhandl, C; Stein, DJ; Strejilevich, S; Subramaniam, M; Sulaiman, AH; Suominen, K; Tagata, H; Tatebayashi, Y; Tondo, L; Torrent, C; Vaaler, Arne; Veeh, J; Vieta, E; Viswanath, B; Yoldi-Negrete, M; Zetin, M; Zgueb, Y & Whybrow, Peter C. (2017). Solar insolation in springtime influences age of onset of bipolar I disorder. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 136(6), s 571- 582 . doi: 10.1111/acps.12772
Berg, Akiah Ottesen; Melle, Ingrid; Zuber, Verena; Simonsen, Carmen Elisabeth; Nerhus, Mari; Ueland, Torill; Andreassen, Ole Andreas; Sundet, Kjetil Søren & Vaskinn, Anja (2017). Modelling difficulties in abstract thinking in psychosis: the importance of socio-developmental background. Cognitive Neuropsychiatry. ISSN 1354-6805. 22(1), s 39- 52 . doi: 10.1080/13546805.2016.1259998
Bjørnestad, Jone Ravndal; Davidson, Larry; Joa, Inge; Larsen, Tor Ketil; Hegelstad, Wenche; Langeveld, Johannes H.; Veseth, Marius; Melle, Ingrid; Johannessen, Jan Olav & Brønnick, Kolbjørn Selvåg (2017). Antipsychotic treatment: experiences of fully recovered service users. Journal of Mental Health. ISSN 0963-8237. 26(3), s 264- 270 . doi: 10.1080/09638237.2017.1294735
Bjørnestad, Jone Ravndal; Hegelstad, Wenche; Joa, Inge; Davidson, Larry; Larsen, Tor Ketil; Melle, Ingrid; Veseth, Marius; Johannessen, Jan Olav & Brønnick, Kolbjørn Selvåg (2017). "With a little help from my friends" social predictors of clinical recovery in first-episode psychosis. Psychiatry Research. ISSN 0165-1781. 255, s 209- 214 . doi: 10.1016/j.psychres.2017.05.041
Church, Chelsea; Andreassen, Ole Andreas; Lorentzen, Steinar; Melle, Ingrid & Aas, Monica (2017). Childhood trauma and minimization/denial in people with and without a severe mental disorder. Frontiers in Psychology. ISSN 1664-1078. 8 . doi: 10.3389/fpsyg.2017.01276
Doan, Nhat Trung; Kaufmann, Tobias; Bettella, Francesco; Jørgensen, Kjetil Nordbø; Brandt, Christine Lycke; Moberget, Torgeir; Alnæs, Dag; Douaud, Gwenaëlle; Duff, Eugene; Djurovic, Srdjan; Melle, Ingrid; Ueland, Torill; Agartz, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders. NeuroImage: Clinical. ISSN 2213-1582. 15, s 719- 731 . doi: 10.1016/j.nicl.2017.06.014 Full text in Research Archive.
Gardsjord, Erlend Strand; Romm, Kristin Lie; Røssberg, Jan Ivar; Friis, Svein; Barder, Helene; Evensen, Julie Horgen; Haahr, Ulrik; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes H.; Larsen, Tor Ketil; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas & Melle, Ingrid (2017). Is going into stable symptomatic remission associated with a more positive development of life satisfaction? A 10-year follow-up study of first episode psychosis. Schizophrenia Research. ISSN 0920-9964. 193, s 364- 369 . doi: 10.1016/j.schres.2017.07.006
Haug, Elisabeth; Øie, Merete Glenne; Andreassen, Ole Andreas; Bratlien, Unni; Barnaby, Nelson; Melle, Ingrid & Møller, Paul (2017). High levels of anomalous self-experience are associated with longer duration of untreated psychosis. Early Intervention in Psychiatry. ISSN 1751-7885. 11(2), s 133- 138 . doi: 10.1111/eip.12220 Full text in Research Archive.
Hibar, Derrek; Adams, Hieab H.H.; Jahanshad, Neda; Chauhan, Ganesh; Stein, Jason L.; Hofer, Edith; Renteriá, Miguel E.; Bis, Joshua C.; Arias-Vasquez, Alejandro; Ikram, M. Kamran; Desrivières, Sylvane; Vernooij, Meike W; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; Beecham, Ashley H.; Beiser, Alexa; Bernard, Manon; Blanton, Susan H.; Bohlken, Marc M.; Boks, Marco P.; Bralten, Janita; Brickman, Adam M.; Carmichael, Owen; Chakravarty, M. Mallar; Chen, Qiang; Ching, Christopher R.K.; Chouraki, Vincent; Cuellar-Partida, Gabriel; Crivello, Fabrice; Den Braber, Anouk; Doan, Nhat Trung; Ehrlich, Stefan; Giddaluru, Sudheer; Goldman, Aaron L; Gottesman, Rebecca F.; Grimm, Oliver; Griswold, Michael E.; Guadalupe, Tulio; Gutman, Boris A.; Hass, Johanna; Haukvik, Unn Kristin H.; Hoehn, David; Holmes, Avram J.; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Jørgensen, Kjetil Nordbø; Karbalai, Nazanin; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H.; Liewald, David C.M.; Lopez, Lorna M.; Luciano, Michelle; MacAre, Christine; Marquand, André F.; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; McKay, David R.; Milaneschi, Yuri; Muñoz Maniega, Susana; Nho, Kwangsik; Nugent, Allison C.; Nyquist, Paul; Loohuis, Loes M. Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pirpamer, Lukas; Pütz, Benno; Ramasamy, Adaikalavan; Richards, Jennifer S.; Risacher, Shannon L.; Roiz-Santiañez, Roberto; Rommelse, Nanda; Ropele, Stefan; Rose, Emma J.; Royle, Natalie A.; Rundek, Tatjana; Sämann, Philipp G.; Saremi, Arvin; Satizabal, Claudia L.; Schmaal, Lianne; Schork, Andrew J.; Shen, Li; Shin, Jean; Shumskaya, Elena; Smith, Albert V.; Sprooten, Emma; Strike, Lachlan T.; Teumer, Alexander; Tordesillas-Gutierrez, Diana; Toro, Roberto; Trabzuni, Daniah; Trompet, Stella; Vaidya, Dhananjay; Van Der Grond, Jeroen; Van Der Lee, Sven J.; Van Der Meer, Dennis; van Donkelaar, Marjolein M.J.; Van Eijk, Kristel R.; Van Erp, Theo G.M.; Van Rooij, Daan; Walton, Esther; Westlye, Lars Tjelta; Whelan, Christopher D.; Windham, Beverly G.; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Wolfers, Thomas; Yanek, Lisa R.; Yang, Jingyun; Zijdenbos, Alex; Zwiers, Marcel P.; Agartz, Ingrid; Almasy, Laura; Ames, David; Amouyel, Philippe; Andreassen, Ole Andreas; Arepalli, Sampath; Assareh, Amelia A.; Barral, Sandra; Bastin, Mark E.; Becker, Diane M.; Becker, James T.; Bennett, David A.; Blangero, John; Van Bokhoven, Hans; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Brunner, Han G.; Buckner, Randy L.; Buitelaar, Jan K.; Bulayeva, Kazima B.; Cahn, Wiepke; Calhoun, Vince D.; Cannon, Dara M.; Cavalleri, Gianpiero L.; Cheng, Ching-Yu; Cichon, Sven; Cookson, Mark R.; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Dale, Anders; Davies, Gareth E.; de Craen, Anton J.M.; de Geus, Eco J.C.; De Jager, Philip L.; de Zubicaray, Greig I.; Deary, Ian J.; Debette, Stéphanie; Decarli, Charles; Delanty, Norman; Depondt, Chantal; Destefano, Anita; Dillman, Allissa; Djurovic, Srdjan; Donohoe, Gary; Drevets, Wayne C.; Duggirala, Ravi; Dyer, Thomas D.; Enzinger, Christian; Erk, Susanne; Espeseth, Thomas; Fedko, Iryna O.; Fernandéz, Guillén; Ferrucci, Luigi; Fisher, Simon E.; Fleischman, Debra A.; Ford, Ian; Fornage, Myriam; Foroud, Tatiana M.; Fox, Peter T.; Francks, Clyde; Fukunaga, Masaki; Gibbs, J. Raphael; Glahn, David C.; Gollub, Randy L.; Göring, Harald H.H.; Green, Robert C.; Gruber, Oliver; Gudnason, Vilmundur; Guelfi, Sebastian; Håberg, Asta; Hansell, Narelle K.; Hardy, John; Hartman, Catharina A.; Hashimoto, Ryota; Hegenscheid, Katrin; Heinz, Andreas; Le Hellard, Stephanie; Hernandez, Dena G.; Heslenfeld, Dirk J.; Ho, Beng-Choon; Hoekstra, Pieter J.; Hoffmann, Wolfgang; Hofman, Albert; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Hottenga, Jouke-Jan; Huentelman, Matthew; Pol, Hilleke E. Hulshoff; Ikeda, Masashi; Jack, Clifford R.; Jenkinson, Mark; Johnson, Robert; Jönsson, Erik Gunnar; Jukema, J. Wouter; Kahn, René S.; Kanai, Ryota; Kloszewska, Iwona; Knopman, David S.; Kochunov, Peter; Kwok, John B.; Lawrie, Stephen M.; Lemaître, Hervé; Liu, Xinmin; Longo, Dan L.; Lopez, Oscar L.; Lovestone, Simon; Martinez, Oliver; Martinot, Jean-Luc; Mattay, Venkata S.; McDonald, Colm; McIntosh, Andrew M.; McMahon, Francis J.; McMahon, Katie L.; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Mohnke, Sebastian; Montgomery, Grant W.; Morris, Derek W.; Mosley, Thomas H.; Mühleisen, Thomas W.; Müller-Myhsok, Bertram; Nalls, Michael A.; Nauck, Matthias; Nichols, Thomas E.; Niessen, Wiro J.; Nöthen, Markus M.; Nyberg, Lars; Ohi, Kazutaka; Olvera, Rene L.; Ophoff, Roel A.; Pandolfo, Massimo; Paus, Tomas; Pausova, Zdenka; Penninx, Brenda W.J.H.; Pike, G. Bruce; Potkin, Steven G.; Psaty, Bruce M.; Reppermund, Simone; Rietschel, Marcella; Roffman, Joshua L.; Romanczuk-Seiferth, Nina; Rotter, Jerome I.; Ryten, Mina; Sacco, Ralph L.; Sachdev, Perminder S.; Saykin, Andrew J.; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter R.; Sigursson, Sigurdur; Simmons, Andrew; Singleton, Andrew; Sisodiya, Sanjay M.; Smith, Colin; Smoller, Jordan W.; Soininen, Hilkka; Steen, Vidar Martin; Stott, David J.; Sussmann, Jessika E; Thalamuthu, Anbupalam; Toga, Arthur W.; Traynor, Bryan J.; Troncoso, Juan; Tsolaki, Magda; Tzourio, Christophe; Uitterlinden, André G.; Hernández, Maria C. Valdés; Van Der Brug, Marcel; Van Der Lugt, Aad; Van Der Wee, Nic J.A.; van Haren, Neeltje E.M.; Van 'T Ent, Dennis; Van Tol, Marie-Jose; Vardarajan, Badri N.; Vellas, Bruno; Veltman, Dick J.; Völzke, Henry; Walter, Henrik; Wardlaw, Joanna M.; Wassink, Thomas H.; Weale, Michael E.; Weinberger, Daniel R.; Weiner, Michael W.; Wen, Wei; Westman, Eric; White, Tonya; Wong, Tien Y.; Wright, Clinton B.; Zielke, Ronald H.; Zonderman, Alan B.; Martin, Nicholas G.; Van Duijn, Cornelia M.; Wright, Margaret J.; Longstreth, William T.; Schumann, Gunter; Grabe, Hans J.; Franke, Barbara; Launer, Lenore J.; Medland, Sarah E.; Seshadri, Sudha; Thompson, Paul M. & Ikram, M. Arfan (2017). Novel genetic loci associated with hippocampal volume. Nature Communications. ISSN 2041-1723. 8:13624, s 1- 12 . doi: 10.1038/ncomms13624 Full text in Research Archive.
Hoseth, Eva Zsuzsanna; Ueland, Thor; Dieset, Ingrid; Birnbaum, Rebecca; Shin, Joo Heon; Kleinman, Joel Edward; Hyde, Thomas Michael; Mørch, Ragni Helene; Hope, Sigrun; Lekva, Tove; Abraityte, Judita Aurelija; Michelsen, Annika; Melle, Ingrid; Westlye, Lars Tjelta; Ueland, Torill; Djurovic, Srdjan; Aukrust, Pål; Weinberger, Daniel R. & Andreassen, Ole Andreas (2017). A study of TNF pathway activation in schizophrenia and bipolar disorder in plasma and brain tissue. Schizophrenia Bulletin. ISSN 0586-7614. 43(4), s 881- 890 . doi: 10.1093/schbul/sbw183 Full text in Research Archive.
Jørgensen, Kjetil Nordbø; Nesvåg, Ragnar; Nerland, Stener; Mørch-Johnsen, Lynn; Westlye, Lars Tjelta; Lange, Elisabeth; Haukvik, Unn Kristin H.; Hartberg, Cecilie Bhandari; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2017). Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 135(2), s 117- 126 . doi: 10.1111/acps.12677
Kaufmann, Tobias; Alnæs, Dag; Brandt, Christine Lycke; Doan, Nhat Trung; Kauppi, Karolina; Bettella, Francesco; Lagerberg, Trine Vik; Berg, Akiah Ottesen; Djurovic, Srdjan; Agartz, Ingrid; Melle, Ingrid; Ueland, Torill; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets. NeuroImage. ISSN 1053-8119. 147, s 243- 252 . doi: 10.1016/j.neuroimage.2016.11.073
Lagerberg, Trine Vik; Aminoff, Sofie Ragnhild; Aas, Monica; Bjella, Thomas; Henry, Chantal; Leboyer, Marion; Pedersen, Geir Feigum; Bellivier, Frank; Icick, Romain; Andreassen, Ole Andreas; Etain, Bruno & Melle, Ingrid (2017). Alcohol use disorders are Associated With increased effective lability in bipolar disorder. Journal of Affective Disorders. ISSN 0165-0327. 208, s 316- 324 . doi: 10.1016/j.jad.2016.09.062
Lam, Max; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Davies, Gail; Liewald, David C.; Starr, John M.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth Trilby; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios A.; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edythe D; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza L.; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian J.; Glahn, David C.; Malhotra, Anil K. & Lencz, Todd (2017). Large-scale cognitive GWAS meta-analysis reveals tissue-specific neural expression and potential nootropic drug targets. Cell reports. ISSN 2211-1247. 21(9), s 2597- 2613 . doi: 10.1016/j.celrep.2017.11.028
Lange, Elisabeth; Nerland, Stener; Jørgensen, Kjetil Nordbø; Mørch-Johnsen, Lynn; Nesvåg, Ragnar; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Osnes, Kåre; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2017). Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls. Psychological Medicine. ISSN 0033-2917. 47(4), s 655- 668 . doi: 10.1017/S0033291716002920
Langeveld, Johannes H.; Bjørkly, Stål; Evensen, Julie Horgen; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Røssberg, Jan Ivar; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; Hegelstad, Wenche; McGlashan, Tom & Friis, Svein (2017). A 10-year follow-up study of violent victimization in first episode psychosis : risk and protective factors. Psychiatry Research. ISSN 0165-1781. 259(January), s 545- 549 . doi: 10.1016/j.psychres.2017.11.013 Show summary
Violent victimization in persons with severe mental illness has long-term adverse consequences. Little is known about the long-term prevalence of victimization in first episode psychosis, or about factors affecting victimization throughout the course of illness. To assess the prevalence of violent victimization during a 10-year follow-up period in a group of first episode psychosis (FEP) patients, and to identify early predictors and risk factors for victimization. A prospective design was used with comprehensive assessments of violent victimization, treatment variables and functioning at baseline and during 10-year follow-up. A clinical epidemiological sample of FEP patients (n= 298) was studied. FEP patients in our study were at a 3.5 times greater risk of victimization as compared to the normal population. During the 10-year follow-up period, 23% of subjects fell victim to one or more violent assaults. Victimized patients were younger and reported less occupational activity. At 10-year follow-up, victimization was associated with more concomitant drug use, alcohol misuse and violent behavior, but not with a worse clinical or functional outcome. Treatment programs should focus on risk factors for victimization and develop behavioral alternatives to mitigate risk in FEP patients.
Le Hellard, Stephanie; Wang, Yunpeng; Witoelar, Aree; Zuber, Verena; Bettella, Francesco; Hugdahl, Kenneth; Espeseth, Thomas; Steen, Vidar Martin; Melle, Ingrid; Desikan, Rahul S.; Schork, Andrew J.; Thompson, Wesley Kurt; Dale, Anders; Djurovic, Srdjan & Andreassen, Ole Andreas (2017). Identification of gene loci that overlap between schizophrenia and educational attainment. Schizophrenia Bulletin. ISSN 0586-7614. 43(3), s 654- 664 . doi: 10.1093/schbul/sbw085
Marshall, Christian R.; Howrigan, Daniel P.; Merico, Daniele; Thiruvahindrapuram, Bhooma; Wu, Wenting; Greer, Douglas S.; Antaki, Danny; Shetty, Aniket; Holmans, Peter A.; Pinto, Dalila; Gujral, Madhusudan; Brandler, William M.; Malhotra, Dheeraj; Wang, Zhouzhi; Fuentes Fajarado, Karin V.; Maile, Michelle S.; Ripke, Stephan; Agartz, Ingrid; Albus, Margot; Alexander, Madeline; Amin, Farooq; Atkins, Joshua; Bacanu, Silviu A.; Belliveau, Richard A.; Bergen, Sarah E.; Bertalan, Marcelo; Bevilacqua, Elizabeth; Bigdeli, Tim B.; Black, Donald W.; Bruggeman, Richard; Buccola, Nancy G.; Buckner, Randy L.; Bulik-Sullivan, Brendan; Byerley, William; Cahn, Wiepke; Cai, Guiqing; Cairns, Murray J.; Campion, Dominique; Cantor, Rita M.; Carr, Vaughan J.; Carrera, Noa; Catts, Stanley V.; Chambert, Kimberly D.; Cheng, Wei; Cloninger, C. Robert; Cohen, David; Cormican, Paul; Craddock, Nick; Crespo-Facorro, Benedicto; Crowley, James J.; Curtis, David; Davidson, Michael; Davis, Kenneth L.; Degenhardt, Franziska; Del Favero, Jurgen; DeLisi, Lynn E.; Dikeos, Dimitris; Dinan, Timothy; Djurovic, Srdjan; Donohoe, Gary; Drapeau, Elodie; Duan, Jubao; Dudbridge, Frank; Eichhammer, Peter; Eriksson, Johan; Escott-Price, Valentina; Essioux, Laurent; Fanous, Ayman H.; Farh, Kai-How; Farrell, Martilias S.; Frank, Josef; Franke, Lude; Freedman, Robert; Freimer, Nelson B.; Friedman, Joseph I.; Forstner, Andreas J.; Fromer, Menachem; Genovese, Giulio; Georgieva, Lyudmila; Gershon, Elliot S.; Giegling, Ina; Giusti-Rodriguez, Paola; Godard, Stephanie; Goldstein, Jacqueline I.; Gratten, Jacob; De Haan, Lieuwe; Hamshere, Marian L.; Hansen, Mark; Hansen, Thomas; Haroutunian, Vahram; Hartmann, Annette M.; Henskens, Frans A.; Herms, Stefan; Hirschhorn, Joel N.; Hoffmann, Per; Hofman, Andrea; Huang, Hailiang; Ikeda, Masashi; Joa, Inge; Kähler, Anna Katarina; Kahn, René S.; Kalaydjieva, Luba; Karjalainen, Juha; Kavanagh, David; Keller, Matthew C.; Kelly, Brian J.; Kennedy, James L.; Kim, Yunjung; Knowles, James A.; Konte, Bettina; Laurent, Claudine; Lee, Phil; Lee, S. Hong; Legge, Sophie E.; Lerer, Bernard; Levy, Deborah L.; Liang, Kung-Yee; Lieberman, Jeffrey; Lonnqvist, Jouko; Loughland, Carmel M.; Magnusson, Patrik K.E.; Maher, Brion S.; Maier, Wolfgang; Mallet, Jacques; Mattheisen, Manuel; Mattingsdal, Morten; McCarley, Robert W.; McDonald, Colm; McIntosh, Andrew M.; Meier, Sandra; Meijer, Carin J.; Melle, Ingrid; Mesholam-Gately, Raquelle I.; Metspalu, Andres; Michie, Patricia T.; Milani, Lili; Milanova, Vihra; Mokrab, Younes; Morris, Derek W.; Muller-Myhsok, Bertram; Murphy, Kieran C.; Murray, Robin M.; Myin-Germeys, Inez; Nenadic, Igor; Nertney, Deborah A.; Nestadt, Gerald; Nicodemus, Kristin K.; Nisenbaum, Laura; Nordin, Annelie; O'Callaghan, Eadbhard; O'Dushlaine, Colm; Oh, Sang-Yun; Olincy, Ann; Olsen, Line; O'Neill, F. Anthony; Van Os, Jim; Pantelis, Christos; Papadimitriou, George N.; Parkhomenko, Elena; Pato, Michele T.; Paunio, Tiina; Perkins, Diana O.; Pers, Tune H.; Pietilainen, Olli; Pimm, Jonathan; Pocklington, Andrew J.; Powell, John; Price, Alkes; Pulver, Ann E.; Purcell, Shaun M.; Quested, Digby; Rasmussen, Henrik B.; Reichenberg, Abraham; Reimers, Mark A.; Richards, Alexander L.; Roffman, Joshua L.; Roussos, Panos; Ruderfer, Douglas M.; Salomaa, Veikko; Sanders, Alan R.; Savitz, Adam; Schall, Ulrich; Schulze, Thomas G.; Schwab, Sibylle G.; Scolnick, Edward M.; Scott, Rodney J.; Seidman, Larry J.; Shi, Jianxin; Silverman, Jeremy M.; Smoller, Jordan W.; Söderman, Erik; Spencer, Chris CA; Stahl, Eli A.; Strengman, Eric; Strohmaier, Jana; Stroup, T. Scott; Suvisaari, Jaana; Svrakic, Dragan M.; Szatkiewicz, Jin P.; Thirumalai, Srinivas; Tooney, Paul A.; Veijola, Juha; Visscher, Peter M.; Waddington, John; Walsh, Dermot; Webb, Bradley T.; Weiser, Mark; Wildenauer, Dieter B.; Williams, Nigel M.; Williams, Stephanie; Witt, Stephanie H.; Wolen, Aaron R.; Wormley, Brandon K.; Wray, Naomi R.; Wu, Jing Qin; Zai, Clement C.; Adolfsson, Rolf; Andreassen, Ole Andreas; Blackwood, Douglas H.R.; Bramon, Elvira; Buxbaum, Joseph D.; Cichon, Sven; Collier, David A.; Corvin, Aiden; Daly, Mark J.; Darvasi, Ariel; Domenici, Enrico; Esko, Tonu; Gejman, Pablo V.; Gill, Michael; Gurling, Hugh; Hultman, Christina M.; Iwata, Nakao; Jablensky, Assen V.; Jönsson, Erik Gunnar; Kendler, Kenneth S.; Kirov, George; Knight, Jo; Levinson, Douglas F.; Li, Qingqin S.; McCarroll, Steven A.; McQuillin, Andrew; Moran, Jennifer L.; Mowry, Bryan J.; Nöthen, Markus M.; Ophoff, Roel A.; Owen, Michael J.; Palotie, Aarno; Pato, Carlos N.; Petryshen, Tracey L.; Posthuma, Danielle; Rietschel, Marcella; Riley, Brien P.; Rujescu, Dan; Sklar, Pamela; St. Clair, David; Walters, James T.R.; Werge, Thomas; Sullivan, Patrick F.; O'Donovan, Michael C.; Scherer, Stephen W.; Neale, Benjamin M. & Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics. ISSN 1061-4036. 49, s 27- 35 . doi: 10.1038/ng.3725
McLaughlin, Russell L.; Schijven, Dick; Van Rheenen, Wouter; Van Eijk, Kristel R.; O'Brien, Margaret; Kahn, René S.; Ophoff, Roel A.; Goris, An; Bradley, Daniel G.; Al-Chalabi, Ammar; van den Berg, Leonard H.; Luykx, Jurjen J.; Hardiman, Orla; Veldink, Jan H.; Agartz, Ingrid; Djurovic, Srdjan; Joa, Inge; Mattingsdal, Morten; Melle, Ingrid & Andreassen, Ole Andreas (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications. ISSN 2041-1723. 8:14774, s 1- 12 . doi: 10.1038/ncomms14774
Melle, Ingrid; Johannessen, Jan Olav; Haahr, Ulrik H.; Hegelstad, Wenche; Joa, Inge; Langeveld, Johannes H.; Larsen, Tor Ketil; Ilner, Stein E. Opjordsmoen; Qin, Ping; Røssberg, Jan Ivar; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas H. & Friis, Svein (2017). Causes and predictors of premature death in first-episode schizophrenia spectrum disorders. World Psychiatry. ISSN 1723-8617. 16(2), s 217- 218 . doi: 10.1002/wps.20431
Mellerup, Erling; Andreassen, Ole Andreas; Bennike, Bente; Dam, H; Djurovic, Srdjan; Jorgensen, Martin Balslev; Kessing, Lars Vedel; Koefoed, Pernille; Melle, Ingrid; Mors, Ole & Moeller, GL (2017). Combinations of genetic variants associated with bipolar disorder.. PLoS ONE. ISSN 1932-6203. 12(12) . doi: 10.1371/journal.pone.0189739
Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Hope, Sigrun; Aas, Monica; Nerhus, Mari; Gardsjord, Erlend Strand; Haram, Marit; Falk, Ragnhild Sørum; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Melle, Ingrid; Ueland, Thor & Andreassen, Ole Andreas (2017). Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 136(4), s 400- 408 . doi: 10.1111/acps.12783
Nerhus, Mari; Berg, Akiah Ottesen; Simonsen, Carmen Elisabeth; Haram, Marit; Haatveit, Beathe Christin; Dahl, Sandra Rinne; Gurholt, Tiril Pedersen; Bjella, Thomas; Ueland, Torill; Andreassen, Ole Andreas & Melle, Ingrid (2017). Vitamin D deficiency associated with cognitive functioning in psychotic disorders. Journal of Clinical Psychiatry. ISSN 0160-6689. 78(7), s e750- e757 . doi: 10.4088/JCP.16m10880
Nesvåg, Ragnar; Jönsson, Erik Gunnar; Bakken, Inger Johanne; Knudsen, Gun Peggy; Bjella, Thomas; Reichborn-Kjennerud, Ted; Melle, Ingrid & Andreassen, Ole Andreas (2017). The quality of severe mental disorder diagnoses in a national health registry as compared to research diagnoses based on structured interview. BMC Psychiatry. ISSN 1471-244X. 17(1) . doi: 10.1186/s12888-017-1256-8 Full text in Research Archive.
Simonsen, Carmen Elisabeth; Færden, Ann; Romm, Kristin Lie; Berg, Akiah Ottesen; Bjella, Thomas; Sundet, Kjetil Søren; Ueland, Torill; Andreassen, Ole Andreas & Melle, Ingrid (2017). Early clinical recovery in first-episode psychosis: Symptomatic remission and its correlates at 1-year follow-up. Psychiatry Research. ISSN 0165-1781. 254, s 118- 125 . doi: 10.1016/j.psychres.2017.04.050
Skåtun, Kristina Cecilie; Kaufmann, Tobias; Brandt, Christine Lycke; Doan, Nhat Trung; Alnæs, Dag; Tønnesen, Siren; Biele, Guido; Vaskinn, Anja; Melle, Ingrid; Agartz, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder. Brain Imaging and Behavior. ISSN 1931-7557. . doi: 10.1007/s11682-017-9714-y
Srinivasan, Saurabh; Bettella, Francesco; Hassani, Sahar; Wang, Yunpeng; Witoelar, Aree; Schork, Andrew J.; Thompson, Wesley Kurt; Collier, David A.; Desikan, Rahul S.; Melle, Ingrid; Dale, Anders; Djurovic, Srdjan & Andreassen, Ole Andreas (2017). Probing the association between early evolutionary markers and schizophrenia. PLoS ONE. ISSN 1932-6203. 12:e0169227(1), s 1- 15 . doi: 10.1371/journal.pone.0169227
Trampush, Joey W.; Yang, M.L.Z.; Yu, Jin; Knowles, Emma; Davies, Gail; Liewald, David C.M.; Starr, John M.; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan Gunnar; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William E.R.; Horan, Michael Arthur; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth Trilby; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios A.; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert Martin; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edyth; Poldrack, Russell Alan; Sabb, Fred W.; Congdon, Eliza L.; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary J.; Morris, Derek W.; Corvin, Aiden; Gill, Michael; Hariri, Ahmad; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Deary, Ian John; Glahn, David C.; Malhotra, Anil K. & Lencz, Todd (2017). GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report form the COGENT consortium. Molecular Psychiatry. ISSN 1359-4184. 22(3), s 336- 345 . doi: 10.1038/mp.2016.244 Full text in Research Archive.
Walton, Esther Fintan; Hibar, Derrek; Van Erp, Theo G.M.; Potkin, Steven G.; Roiz-Santiáñez, Roberto; Crespo-Facorro, Benedicto; Suarez-Pinilla, Paula; van Haren, Neeltje E.M.; de Zwarte, Sonja M.C.; Kahn, René S.; Cahn, Wiepke; Doan, Nhat Trung; Jørgensen, Kjetil Nordbø; Gurholt, Tiril Pedersen; Agartz, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta; Melle, Ingrid; Berg, Akiah Ottesen; Mørch-Johnsen, Lynn; Færden, Ann; Flyckt, Lena; Fatouros-Bergman, Helena; Jönsson, Erik Gunnar; Hashimoto, Ryota; Yamamori, Hidenaga; Fukunaga, Masaki; Preda, Adrian; De Rossi, Pietro; Piras, Fabrizio; Banaj, Nerisa; Ciullo, Valentina; Spalletta, Gianfranco; Gur, Raquel E.; Gur, Ruben C.; Wolf, Daniel H.; Satterthwaite, Theaodore D.; Beard, Lauren M.; Sommer, Iris E.; Koops, Sanne; Gruber, Oliver; Richter, Anja; Krämer, B.; Kelly, Sinéad; Donohoe, Gary J.; McDonald, Colm; Cannon, Dara M.; Corvin, Aiden; Gill, Michael; Di Giorgio, Annabella; Bertolino, Alessandro; Lawrie, Stephen M.; Nickson, Thomas; Whalley, Heather Clare; Neilson, Emma; Calhoun, Vince D.; Thompson, Paul Murray; Turner, Jessica A. & Ehrlich, Stefan (2017). Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 135(5), s 439- 447 . doi: 10.1111/acps.12718
Weibell, Melissa Anne; Hegelstad, Wenche; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Evensen, Julie Horgen; Haahr, Ulrik; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas; McGorry, Patrick & Friis, Svein (2017). The Effect of Substance Use on 10-Year Outcome in First-Episode Psychosis. Schizophrenia Bulletin. ISSN 0586-7614. 43(4), s 843- 851 . doi: 10.1093/schbul/sbw179
Østefjells, Tiril; Lystad, June Ullevoldsæter; Berg, Akiah Ottesen; Hagen, Roger; Loewy, R; Sandvik, Leiv; Melle, Ingrid & Røssberg, Jan Ivar (2017). Metacognitive beliefs mediate the effect of emotional abuse on depressive and psychotic symptoms in severe mental disorders. Psychological Medicine. ISSN 0033-2917. 47(13), s 2323- 2333 . doi: 10.1017/S0033291717000848
Østefjells, Tiril; Melle, Ingrid; Aminoff, Sofie Ragnhild; Hellvin, Tone; Hagen, Roger; Lagerberg, Trine Vik; Lystad, June Ullevoldsæter & Røssberg, Jan Ivar (2017). An exploration of metacognitive beliefs and thought control strategies in bipolar disorder. Comprehensive Psychiatry. ISSN 0010-440X. 73, s 84- 92 . doi: 10.1016/j.comppsych.2016.11.008 Show summary
Background: Previous studies have shown that individuals with schizophrenia exhibit higher levels of unhelpful metacognitive beliefs than healthy controls, but no studies have explored metacognitive beliefs in early psychosis. Aims: We examined i) differences in levels of unhelpful metacognitive beliefs between psychosis spectrum disorders, and healthy controls, and ii) to what extent demographic and clinical characteristics predicted levels of metacognitive beliefs in the early treated phases of psychotic disorders. Method: Patients were included within two years of first treatment for a psychotic disorder (N=92). They were assessed on premorbid adjustment, psychotic symptoms, anxiety/depression, and self-reported metacognitive beliefs (MCQ-30). Ninety-seven controls also completed MCQ-30. Predictors of metacognitive beliefs were explored with multiple linear regression analyses. Results: Patients scored significantly higher than controls on all metacognitive subscales except positive beliefs about worry. The regression model explained 14—38% of the variance on each metacognitive subscale. Current affective symptoms explained a significant amount of variance on all subscales, except positive beliefs about worry. Childhood (premorbid) social adjustment predicted a significant amount of the variance on all subscales, except cognitive confidence. Duration of untreated psychosis contributed significantly to more unhelpful beliefs about cognitive confidence. Negative symptoms predicted lower scores on cognitive self-consciousness. Conclusion: Affective symptoms and childhood social adjustment could be important predictors of unhelpful metacognitive beliefs in the early treated phases of psychosis, indicating potential psychopathological relationships that warrant further investigation for clinical relevance.

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Malt, Ulrik Fredrik; Andreassen, Ole Andreas; Malt, Eva Albertsen; Melle, Ingrid & Aarsland, Dag (red.) (2018). Lærebok i psykiatri. Gyldendal Akademisk. ISBN 978-82-05-49463-3. 1060 s.

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Aminoff, Sofie Ragnhild; Henry, Chantal; Bettella, Francesco; Etain, Bruno; Berg, Akiah Ottesen; Lagerberg, Trine Vik; Bjella, Thomas; Aas, Monica; Djurovic, Srdjan; Bellivier, Frank; Andreassen, Ole Andreas & Melle, Ingrid (2018). Affective lability and polygenic risk in bipolar disorder.
Andreassen, Ole Andreas; Malt, Eva Albertsen; Malt, Ulrik Fredrik; Aarsland, Dag & Melle, Ingrid (2018). Biopsykososial forståelsesmodell, I: Ulrik Fredrik Malt; Ole Andreas Andreassen; Eva Albertsen Malt; Ingrid Melle & Dag Aarsland (red.), Lærebok i psykiatri. Gyldendal Akademisk. ISBN 978-82-05-49463-3. Kapittel 6. s 135 - 142
Berg, Akiah Ottesen; Melle, Ingrid & Nerhus, Mari (2018). ENVIRONAMNETAL RISK FACTORS AND SYMPTOMS IN IMMIGRANTS WITH PSYCHOTIC DISORDER.
Gurholt, Tiril Pedersen; Nerhus, Mari; Osnes, Kåre; Berg, Akiah Ottesen; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2018). Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D. Schizophrenia Research. ISSN 0920-9964. 199, s 433- 435 . doi: 10.1016/j.schres.2018.03.011
Lam, Max; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widén, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Attix, Deborah K.; Need, Anna C.; Cirulli, Elizabeth T.; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios; Hatzimanolis, Alex; Arking, Dan E.; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson A.; Cannon, Tyrone D.; London, Edythe; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Le Hellard, Stephanie; Keller, Matthew C.; Andreassen, Ole Andreas; Glahn, David C.; Malhotra, Anil K. & Lencz, Todd (2018). Multi-Trait analysis of gwas and biological insights into cognition: A response to Hill (2018). Twin Research and Human Genetics. ISSN 1832-4274. 21(5), s 394- 397 . doi: 10.1017/thg.2018.46
Lunde, Ketil Berge; Mehlum, Lars; Stanley, Barbara; Melle, Ingrid & Qin, Ping (2018). The influence of sick leave and sociodemographic factors on risk for deliberate self-harm: A national study.
Svendsen, Ingrid Hartveit; Øie, Merete Glenne; Møller, Paul; Nelson, Barnaby; Melle, Ingrid & Haug, Elisabeth (2018). Self-disturbances and diagnostic stability in first episode psychosis- a seven year follow-up study.
Vedal, Trude Seselie Jahr; Steen, Nils Eiel; Birkeland, Kåre I.; Dieset, Ingrid; Reponen, Elina Johanna; Laskemoen, Jannicke F.; Rødevand, Linn; Melle, Ingrid; Andreassen, Ole Andreas; Molden, Espen & Jönsson, Erik Gunnar (2018). Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?. Journal of Psychiatric Research. ISSN 0022-3956. . doi: 10.1016/j.jpsychires.2018.11.012
Gurholt, Tiril Pedersen; Nerhus, Mari; Osnes, Kåre; Jørgensen, Kjetil Nordbø; Berg, Akiah Ottesen; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2017). Age-Related Effect of Vitamin D on Hippocampus Volume in Schizophrenia and Bipolar Disorder.
Storvestre, Guttorm Breivik; Valnes, Lars Magnus; Jensen, Arvid; Agartz, Ingrid; Jacobsen, Morten; Andreassen, Ole; Melle, Ingrid & Haukvik, Unn Kristin H. (2017). Regional cortical folding and thickness differences between schizophrenia patients with and without a history of severe violence.

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Published Apr. 13, 2011 2:54 PM - Last modified Nov. 13, 2018 12:07 PM

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Early-Onset Schizophrenia and ADHD

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Illness trajectories and outcome prediction

Ingrid Melle

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