Karine Flem Karlsen

Postdoctoral Fellow - Department of Pharmacology
Image of Karine Flem Karlsen
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postal address Postboks 1057 Blindern 0316 Oslo

Publications

  • Flem-Karlsen, Karine; Fodstad, Øystein & Nunes-Xavier, Caroline Elisabeth (2020). B7-H3 immune checkpoint protein in human cancer. Current Medicinal Chemistry.  ISSN 0929-8673.  27(24), s 4062- 4086 . doi: 10.2174/0929867326666190517115515
  • Flem-Karlsen, Karine; Nyakas, Marta Sølvi; Farstad, Inger Nina; McFadden, Erin; Vernhoff, Patrik; Jacobsen, Kari Dolven; Flørenes, Vivi Ann & Mælandsmo, Gunhild Mari (2020). Soluble AXL as a marker of disease progression and survival in melanoma. PLOS ONE.  ISSN 1932-6203.  15:e0227187(1), s 1- 17 . doi: 10.1371/journal.pone.0227187 Full text in Research Archive.
  • Flem-Karlsen, Karine; Tekle, Christina; Øyjord, Tove Ragnhild; Flørenes, Vivi Ann; Mælandsmo, Gunhild Mari; Fodstad, Øystein & Nunes-Xavier, Caroline Elisabeth (2019). p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance. Scientific Reports.  ISSN 2045-2322.  9(1) . doi: 10.1038/s41598-019-42303-w Full text in Research Archive.
  • Flørenes, Vivi Ann; Flem-Karlsen, Karine; McFadden, Erin; Bergheim, Inger Riise; Nygaard, Vigdis; Nygård, Vegard Mokleiv; Farstad, Inger Nina; Øy, Geir Frode; Emilsen, Elisabeth; Fleten, Karianne Giller; Ree, Anne Hansen; Flatmark, Kjersti; Gullestad, Hans Petter; Hermann, Robert; Ryder, Truls; Wernhoff, Patrik & Mælandsmo, Gunhild Mari (2019). A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases. Translational Oncology.  ISSN 1944-7124.  12(7), s 951- 958 . doi: 10.1016/j.tranon.2019.04.001 Full text in Research Archive.
  • Karlsen, Karine Flem; McFadden, Erin; Flørenes, Vivi Ann & Davidson, Ben (2019). Soluble AXL is ubiquitously present in malignant serous effusions. Gynecologic Oncology.  ISSN 0090-8258.  152(2), s 408- 415 . doi: 10.1016/j.ygyno.2018.11.012
  • Karlsen, Karine Flem; McFadden, Erin; Omar, Nasrin; Haugen, Mads Haugland; Øy, Geir Frode; Ryder, Truls; Gullestad, Hans Petter; Hermann, Robert; Mælandsmo, Gunhild Mari & Flørenes, Vivi Ann (2019). Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma. Molecular Cancer Therapeutics.  ISSN 1535-7163.  19(3), s 895- 905 . doi: 10.1158/1535-7163.MCT-19-0290 Full text in Research Archive.
  • Karlsen, Karine Flem; Fodstad, Øystein; Tan, Ming & Nunes-Xavier, Caroline Elisabeth (2018). B7-H3 in Cancer ? Beyond Immune Regulation. Trends in Cancer.  ISSN 2405-8033. . doi: 10.1016/j.trecan.2018.03.010 Full text in Research Archive.
  • Karlsen, Karine Flem; Tekle, Christina; Andersson, Yvonne; Flatmark, Kjersti; Fodstad, Øystein & Nunes-Xavier, Caroline Elisabeth (2017). Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells. Pigment Cell & Melanoma Research.  ISSN 1755-1471.  30(5), s 467- 476 . doi: 10.1111/pcmr.12599 Full text in Research Archive.
  • Nunes-Xavier, Caroline Elisabeth; Flem Karlsen, Karine; Tekle, Christina; Pedersen, Cathrine; Øyjord, Tove Ragnhild; Hongisto, Vesa; Nesland, Jahn M; Tan, Ming; Sahlberg, Kristine Kleivi & Fodstad, Øystein (2016). Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors. OncoTarget.  ISSN 1949-2553.  7(6), s 6891- 6901 . doi: 10.18632/oncotarget.6902 Full text in Research Archive.

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  • Flem-Karlsen, Karine (2020). Investigating therapeutic candidates and the use of preclinical models to predict treatment response in melanoma. Full text in Research Archive.
  • Flem-Karlsen, Karine & Flørenes, Vivi Ann (2020). Investigating therapeutic candidates and the use of preclinical models to predict treatment response in melanoma.

View all works in Cristin

Published Dec. 12, 2019 3:04 PM - Last modified Dec. 12, 2019 3:04 PM