Tor Skomedal

Professor Emeritus - Department of Pharmacology
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postal address Postboks 1057 Blindern 0316 Oslo

Publications

  • Melsom, Elin Maria Caroline Bull; Cosson, Marie-Victoire; Ørstavik, Øivind; Lai, Ngai Chin; Hammond, H. Kirk & Osnes, Jan-Bjørn [Show all 10 contributors for this article] (2019). Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. PLOS ONE. ISSN 1932-6203. 14:e021810(6), p. 1–19. doi: 10.1371/journal.pone.0218110. Full text in Research Archive
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2018). Mental Health and Disability Pension Onset: Changes in Consumption of Antianxiety and Hypnotic Drugs. Health Services Research and Managerial Epidemiology. ISSN 2333-3928. 5, p. 1–5. doi: 10.1177/2333392818792683. Full text in Research Archive
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Hougen, Karina & Skomedal, Tor [Show all 10 contributors for this article] (2017). PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts. European Journal of Pharmacology. ISSN 0014-2999. 812, p. 174–183. doi: 10.1016/j.ejphar.2017.07.014.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2017). New benzodiazepine and Z-hypnotic users and disability pension: an eight-year nationwide observational follow-up study. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 35(3), p. 240–246. doi: 10.1080/02813432.2017.1358436.
  • Eikemo, Hilde; Moltzau, Lise Roman; Nguyen, Hong Cam Thi; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn (2016). CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 477(1), p. 14–19. doi: 10.1016/j.bbrc.2016.05.138.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2016). A 5-year follow-up study of users of benzodiazepine: starting with diazepam versus oxazepam. British Journal of General Practice. ISSN 0960-1643. 66(645), p. e241–e247. doi: 10.3399/bjgp16X684385.
  • Eikemo, Hilde; Moltzau, Lise Roman; Hussain, Rizwan; Nguyen, Hong Cam Thi; Qvigstad, Eirik & Skomedal, Tor [Show all 8 contributors for this article] (2016). CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 471(1), p. 219–225. doi: 10.1016/j.bbrc.2016.01.132.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Risk factors for excessive benzodiazepine use in a working age population – a nationwide 5-year survey in Norway. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 33(4), p. 252–259. doi: 10.3109/02813432.2015.1117282.
  • Ørstavik, Øivind; Manfra, Ornella; Andressen, Kjetil Wessel; Andersen, Geir Øystein; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2015). The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium. PLOS ONE. ISSN 1932-6203. 10(3). doi: 10.1371/journal.pone.0115547. Full text in Research Archive
  • Ørstavik, Øivind; Ata, Salmana H; Riise, Jon; Dahl, Christen Peder; Andersen, Geir Øystein & Levy, Finn Olav [Show all 9 contributors for this article] (2014). Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart. British Journal of Pharmacology. ISSN 0007-1188. 171(23), p. 5169–5181. doi: 10.1111/bph.12647.
  • Melsom, Elin Maria Caroline Bull; Ørstavik, Øivind; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2014). Gi proteins regulate adenylyl cyclase activity independent of receptor activation. PLoS Medicine. ISSN 1549-1277. 9:e0106608(9). doi: 10.1371/journal.pone.0106608. Full text in Research Archive
  • Melsom, Elin Maria Caroline Bull; Hussain, Rizwan; Ørstavik, Øivind; Aronsen, Jan Magnus; Sjaastad, Ivar & Skomedal, Tor [Show all 9 contributors for this article] (2014). Non-classical regulation of β1- and β2 adrenoceptor- mediated inotropic responses in rat ventricle by the G protein Gi. Naunyn-Schmiedeberg's Archives of Pharmacology. ISSN 0028-1298. 387(12), p. 1177–1186. doi: 10.1007/s00210-014-1036-7.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Skogestad, Jonas; Ørstavik, Øivind & Lothe, Gustav B [Show all 11 contributors for this article] (2014). Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. doi: 10.1124/jpet.114.214882.
  • Moltzau, Lise Roman; Meier, Silja; Aronsen, Jan Magnus; Afzal, Faraz; Sjaastad, Ivar & Skomedal, Tor [Show all 9 contributors for this article] (2014). Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium. Naunyn-Schmiedeberg's Archives of Pharmacology. ISSN 0028-1298. 387(5), p. 407–417. doi: 10.1007/s00210-013-0953-1.
  • Bach, Trond; Bergholtz, Stine Louise; Riise, Jon; Qvigstad, Eirik; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 7 contributors for this article] (2014). Identification of small molecule NPR-B antagonists by high throughput screening - potential use in heart failure. Naunyn-Schmiedeberg's Archives of Pharmacology. ISSN 0028-1298. 387(1), p. 5–14. doi: 10.1007/s00210-013-0940-6.
  • Lei, Peng; Baysa, Anton; Nebb, Hilde Irene; Valen, Guro; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2013). Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. Basic Research in Cardiology. ISSN 0300-8428. 108. doi: 10.1007/s00395-012-0323-z.
  • Tvete, Ingunn Fride; Bjørner, Trine; Aursnes, Ivar & Skomedal, Tor (2013). A 3-year survey quantifying the risk of dose escalation of benzodiazepines and congeners to identify risk factors to aid doctors to more rationale prescribing. BMJ Open. ISSN 2044-6055. 3(10). doi: 10.1136/bmjopen-2013-003296.
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Krobert, Kurt Allen; Edvardsen, Thor & Moe, Ingvild Tronstad [Show all 13 contributors for this article] (2013). Connective Tissue Growth Factor/CCN2 Attenuates beta-Adrenergic Receptor Responsiveness and Cardiotoxicity by Induction of G Protein-Coupled Receptor Kinase-5 in Cardiomyocytes. Molecular Pharmacology. ISSN 0026-895X. 84(3), p. 372–383. doi: 10.1124/mol.113.087312.
  • Bjørner, Trine; Tvete, Ingunn Fride; Aursnes, Ivar & Skomedal, Tor (2013). Utlevering av benzodiazepiner og z-hypnotika fra norske apotek 2004-2011. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 133(20), p. 2149–2153. doi: 10.4045/tidsskr.11.0543.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Hong Cam Thi; Hougen, Karina & Ørstavik, Øivind [Show all 12 contributors for this article] (2013). SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium. British Journal of Pharmacology. ISSN 0007-1188. 170(2), p. 366–379. doi: 10.1111/bph.12282.
  • Hussain, Rizwan; Aronsen, Jan Magnus; Afzal, Faraz; Sjaastad, Ivar; Osnes, Jan-Bjørn & Skomedal, Tor [Show all 8 contributors for this article] (2013). The functional activity of inhibitory G protein (Gi) is not increased in failing heart ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 56, p. 129–138. doi: 10.1016/j.yjmcc.2012.11.015.
  • Riise, Jon; Nguyen, Hong Cam Thi; Hussain, Rizwan; Dahl, Christen Peder; Ege, Maren Stapnes & Osnes, Jan-Bjørn [Show all 10 contributors for this article] (2012). Prostanoid-mediated inotropic responses are attenuated in failing human and rat ventricular myocardium. European Journal of Pharmacology. ISSN 0014-2999. 686(1-3), p. 66–73. doi: 10.1016/j.ejphar.2012.04.022.
  • Riise, Jon; Ørstavik, Øivind; Qvigstad, Eirik; Dahl, Christen Peder; Osnes, Jan-Bjørn & Skomedal, Tor [Show all 8 contributors for this article] (2012). Prostaglandin E-1 facilitates inotropic effects of 5-HT4 serotonin receptors and beta-adrenoceptors in failing human heart. Basic Research in Cardiology. ISSN 0300-8428. 107(5). doi: 10.1007/s00395-012-0295-z.
  • Brattelid, Trond; Qvigstad, Eirik; Moltzau, Lise Roman; Bekkevold, Silje Veslemøy; Sandnes, Dagny Lise & Birkeland, Jon Arne [Show all 10 contributors for this article] (2012). The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure. PLOS ONE. ISSN 1932-6203. 7(9). doi: 10.1371/journal.pone.0045489. Full text in Research Archive
  • Klemp, Marianne; Tvete, Ingunn Fride; Skomedal, Tor; Gåsemyr, Jørund Inge; Natvig, Bent & Aursnes, Ivar (2011). A Review and Bayesian Meta-Analysis of Clinical Efficacy and Adverse Effects of 4 Atypical Neuroleptic Drugs Compared With Haloperidol and Placebo. Journal of Clinical Psychopharmacology. ISSN 0271-0749. 31(6), p. 698–704. doi: 10.1097/JCP.0b013e31823657d9.
  • Afzal, Faraz; Qvigstad, Eirik; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar & Skomedal, Tor [Show all 8 contributors for this article] (2011). Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle. Naunyn-Schmiedeberg's Archives of Pharmacology. ISSN 0028-1298. 384(6), p. 543–553. doi: 10.1007/s00210-011-0670-6.
  • Afzal, Faraz; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Levy, Finn Olav & Skomedal, Tor [Show all 8 contributors for this article] (2011). Differential regulation of beta(2)-adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle. British Journal of Pharmacology. ISSN 0007-1188. 162(1), p. 54–71. doi: 10.1111/j.1476-5381.2010.00890.x.
  • Hussain, Rizwan; Afzal, Faraz; Mørk, Halvor Kjeang; Aronsen, Jan Magnus; Sjaastad, Ivar & Osnes, Jan-Bjørn [Show all 9 contributors for this article] (2011). Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle. British Journal of Pharmacology. ISSN 0007-1188. 162(4), p. 908–916. doi: 10.1111/j.1476-5381.2010.01097.x.
  • Qvigstad, Eirik; Moltzau, Lise Roman; Aronsen, Jan Magnus; Nguyen, Hong Cam Thi; Hougen, Karina & Sjaastad, Ivar [Show all 9 contributors for this article] (2010). Natriuretic peptides increase beta(1)-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition. Cardiovascular Research (CVR). ISSN 0008-6363. 85(4), p. 763–772. doi: 10.1093/cvr/cvp364.
  • Hussain, RI; Qvigstad, Eirik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A & Sjaastad, Ivar [Show all 10 contributors for this article] (2009). Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology. ISSN 0007-1188. 156(4), p. 575–586. doi: 10.1111/j.1476-5381.2009.00016.x.
  • Ansteinsson, V; Refsnes, Magne; Skomedal, T; Osnes, JB; Gutowska-Schiander, Iwona & Schiander, I [Show all 7 contributors for this article] (2009). Zinc- and copper-induced interleukin-6 release in primary cell cultures from rat heart. Cardiovascular Toxicology. ISSN 1530-7905. 9(2), p. 86–94. doi: 10.1007/s12012-009-9043-5.
  • Kjekshus, John; Torp-Pedersen, C; Gullestad, Lars; Kober, L; Edvardsen, Thor & Olsen, IC [Show all 11 contributors for this article] (2009). Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure. European Journal of Heart Failure. ISSN 1388-9842. 11(8), p. 771–778. doi: 10.1093/eurjhf/hfp087.
  • Hussain, Rizwan; Qvigstad, Erik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A & Sjaastad, Ivar [Show all 10 contributors for this article] (2009). Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology. ISSN 0007-1188. 156(4), p. 575–586. doi: 10.1111/j.1750-3639.2009.00016.x.
  • Eikemo, Hilde; Skomedal, Tor; Levy, Finn Olav & Osnes, Jan-Bjørn (2008). Calculating reaction rate constants and estimating the efficacy of selective enzyme inhibitors. Analytical Biochemistry. ISSN 0003-2697. 383(2), p. 323–325. doi: 10.1016/j.ab.2008.09.011.
  • Vinge, Leif Erik; von Lueder, Thomas Gero; Aasum, E; Qvigstad, Eirik; Gravning, Jørgen Amundsen & How, OJ [Show all 17 contributors for this article] (2008). Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 uncovers distinct functions of GRK3 in regulation of cardiac contractility and growth - GRK3 controls cardiac alpha(1)-adrenergic receptor responsiveness. Journal of Biological Chemistry. ISSN 0021-9258. 283. doi: 10.1074/jbc.M708912200.
  • Totlandsdal, Annike Irene; Refsnes, Magne; Skomedal, Tor; Osnes, Jan-Bjørn; Schwarze, Per E & Låg, Marit (2008). Particle-induced cytokine responses in cardiac cell cultures-the effect of particles versus soluble mediators released by particle-exposed lung cells. Toxicological Sciences. ISSN 1096-6080. 106(1), p. 233–241. doi: 10.1093/toxsci/kfn162.
  • Riise, J; Nguyen, Hong Cam Thi; Qvigstad, Eirik; Sandnes, Dagny Lise; Osnes, Jan-Bjørn & Skomedal, Tor [Show all 8 contributors for this article] (2008). Prostanoid F receptors elicit an inotropic effect in rat left ventricle by enhancing myosin light chain phosphorylation. Cardiovascular Research (CVR). ISSN 0008-6363. 80(3), p. 407–415. doi: 10.1093/cvr/cvn216.
  • Afzal, Faraz; Andressen, Kjetil Wessel; Mørk, Halvor Kjeang; Aronsen, Jan Magnus; Sjaastad, Ivar & Dahl, Christen Peder [Show all 10 contributors for this article] (2008). 5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles. British Journal of Pharmacology. ISSN 0007-1188. 155(7), p. 1005–1014. doi: 10.1038/bjp.2008.339.
  • Levy, Finn Olav; Qvigstad, Eirik; Krobert, Kurt Allen; Skomedal, Tor & Osnes, Jan-Bjørn (2008). Effects of serotonin in failing cardiac ventricle: Signalling mechanisms and potential therapeutic implications. Neuropharmacology. ISSN 0028-3908. 55(6), p. 1066–1071. doi: 10.1016/j.neuropharm.2008.07.010.
  • Totlandsdal, Annike Irene; Skomedal, Tor; Låg, Marit; Osnes, Jan-Bjørn & Refsnes, Magne (2008). Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells. Toxicology. ISSN 0300-483X. 247(1), p. 23–32. doi: 10.1016/j.tox.2008.01.019.
  • Skomedal, Tor & Osnes, Jan-Bjørn (2007). Endring av anbefalt terapeutisk serumkonsentrasjonsområde for digoksin og digitoksin. Hjerteforum. ISSN 0802-1465. 20(4), p. 27–31.
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti & Krobert, Kurt Allen [Show all 11 contributors for this article] (2007). Effects of treatment with a 5-HT4 receptor antagonist in heart failure. British Journal of Pharmacology. ISSN 0007-1188. 150, p. 143–152. doi: 10.1038/sj.bjp.0706966.
  • Brattelid, Trond; Tveit, Kristine; Birkeland, Jon Arne; Sjaastad, Ivar; Qvigstad, Eirik & Krobert, Kurt Allen [Show all 10 contributors for this article] (2007). Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure : A quantitative RT-PCR study and the question of normalisation. Basic Research in Cardiology. ISSN 0300-8428. 102, p. 198–208. doi: 10.1007/s00395-007-0648-1.
  • Vinge, Leif Erik; Andressen, Kjetil Wessel; Attramadal, Toril; Andersen, Geir Øystein; Ahmed, Muhammad Shakil & Peppel, K [Show all 12 contributors for this article] (2007). Substrate specificities of G protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function. Molecular Pharmacology. ISSN 0026-895X. 72, p. 582–591.
  • Brattelid, Trond; Qvigstad, E; Birkeland, Jan Magne; Birkeland, Jon Arne; Swift, F & Bekkevold, SVS [Show all 12 contributors for this article] (2007). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 43, p. 767–779. doi: 10.1016/j.yjmcc.2007.08.019.
  • Andersen, Geir Øystein; Øie, Erik; Vinge, Leif Erik; Yndestad, Arne; Attramadal, Håvard & Skomedal, Tor [Show all 7 contributors for this article] (2006). Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts. Basic Research in Cardiology. ISSN 0300-8428. 101(6), p. 471–478.

View all works in Cristin

  • Tvete, Ingunn Fride; Skomedal, Tor & Bjørner, Trine (2018). Use and abuse of benzodiazepines in Norway and determinants of drug dependency.
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 9 contributors for this article] (2015). Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts. BMC Pharmacology & Toxicology. ISSN 2050-6511. 16, p. A66–A66. doi: 10.1186/2050-6511-16-S1-A66.
  • Marshall, Serena; Aronsen, Jan Magnus; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B & Lunde, Per Kristian [Show all 13 contributors for this article] (2015). Dual PDE3A coupling to AKAP18 and SERCA2 Controls SERCA2 Activity in adult cardiomyocytes.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Differences in starting with diazepam versus oxazepam: a five year follow-up prescription registry study.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Long-term benzodiazepine use and risk factors for dose escalation .
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Risiko for å utvikle et høyt benzodiazepinforbruk.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Risiko for å utvikle et høyt benzodiazepinforbruk over tid.
  • Meier, Silja; Moltzau, Lise Roman; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2014). Enhancement of B1 - adrenoceptor signaling by CNP through NPR-B and regulation by phosphodiesterases in normal and failing hearts.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2014). Bruk av benzodiazepiner og risikofaktorer for overforbruk.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2014). Benzodiazepine drug dispensing and risk of abuse.
  • Tvete, Ingunn Fride; Natvig, Bent; Gåsemyr, Jørund Inge; Meland, Nils; Røine, Marianne & Skomedal, Tor [Show all 7 contributors for this article] (2014). Treating patients with Rheumatoid arthritis: a Mixed Treatment Comparison analysis of anti-TNF drug effects.
  • Tvete, Ingunn Fride; Gåsemyr, Jørund Inge; Natvig, Bent; Meland, Nils; Marianne, Roine & Skomedal, Tor [Show all 7 contributors for this article] (2014). A Mixed Treatment Comparison analysis of drugs for treating patients with Rheumatoid arthritis.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2014). Risk of excessive Benzodiazepine redeeming over time -a nationwide observational study.
  • Tvete, Ingunn Fride; Bjørner, Trine; Skomedal, Tor & Aursnes, Ivar (2013). En flerårig studie av benzodiazepinbruk i Norge - risikofaktorer for doseøkning.
  • Tvete, Ingunn Fride; Klemp, Marianne ; Natvig, Bent; Gåsemyr, Jørund Inge; Skomedal, Tor & Roine, Marianne [Show all 7 contributors for this article] (2013). Multiple treatment comparison analysis.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2013). Benzodiazepinbruk i Norge over tid.
  • Tvete, Ingunn Fride; Bjørner, Trine; Aursnes, Ivar & Skomedal, Tor (2013). Bruk av benzodiazepiner og risiko for doseeskalering.
  • Skomedal, Tor; Hanem, Sigrid; Dybvik, Terje & Ilner, Stein Opjordsmoen (2013). Olanzapin depot kan gi en tilstand som er forenlig med sentralt antikolinergt syndrom. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 133(21), p. 2238–2239.
  • Aronsen, Jan Magnus; Hougen, Karina; Skogestad, Jonas; Lunde, Marianne; Enger, Ulla Helene & Moltzau, Lise Roman [Show all 11 contributors for this article] (2013). PDE3A is part of the SERCA2-AKAP18 macromolecular complex in cardiomyocytes.
  • Aronsen, Jan Magnus; Aronsen, Jan Magnus; Hougen, Karina; Skogestad, Jonas; Enger, Ulla Helene & Moltzau, Lise Roman [Show all 11 contributors for this article] (2012). PDE3A is part of the SERCA2-AKAP18 macromolecular complex in cardiomyocytes.
  • Hougen, Karina; Aronsen, Jan Magnus; Skogestad, Jonas; Enger, Ulla Helene; Moltzau, Lise Roman & Qvigstad, Eirik [Show all 10 contributors for this article] (2012). PDE3A is part of the SERCA2-AKAP18delta macromolecular complex in cardiomyocytes.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2012). NPR-A and NPR-B signal in different functional compartments in failing rat left ventricle. Cardiovascular Research (CVR). ISSN 0008-6363. 93, p. S18–S18. doi: 10.1093/cvr/cvr332.
  • Tvete, Ingunn Fride; Bjørner, Trine; Skomedal, Tor & Aursnes, Ivar (2012). Dose Escalation of Benzodiazepines and Congeners.
  • Melsom, CB; Hussain, Rizwan; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn & Skomedal, Tor [Show all 8 contributors for this article] (2011). The role of inhibitory G protein upon beta-adrenoceptor-mediated signalling and inotropic responses in normal and failing rat heart left ventricle: Functional evidence of "tonic" Gi activation.
  • Meier, Silja; Aronsen, Jan Magnus; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 7 contributors for this article] (2011). Enhancement of B1-adrenoceptor signaling by C-type natriuretic peptide through natriuretic peptide receptor B in normal and failing hearts: regulation by phosphodiesterases.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve & Sjaastad, Ivar [Show all 10 contributors for this article] (2011). The negative inotropic and positive lusitropic responses to CNP are dependent on SERCA2 activity in failing rat ventricle.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve & Sjaastad, Ivar [Show all 10 contributors for this article] (2011). The mechanism of CNP-induced negative inotropic and positive lusitropic responses are dependent on SERCA activity in failing rat ventricle.
  • Tvete, Ingunn Fride; Klemp, Marianne; Skomedal, Tor; Gaasemyr, Jørund; Natvig, Bent & Aursnes, Ivar Andreas (2010). Clinical efficacy and adverse effects of several antipsychotics.
  • Tvete, Ingunn Fride; Klemp, Marianne; Skomedal, Tor; Gaasemyr, Jørund; Natvig, Bent & Aursnes, Ivar Andreas (2010). Clinical efficacy and adverse effects of the partial dopaminergic agonist aripiprazole compared with other antipsychotics.
  • Meier, Silja; Levy, Finn Olav; Skomedal, Tor; Qvigstad, Eirik & Osnes, Jan-Bjørn (2010). Cardiac tissue hypothyroidism and receptor functions in heart failure.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Hong Cam Thi; Afzal, Faraz & Sjaastad, Ivar [Show all 10 contributors for this article] (2010). Compartmentation of the cGMP signal causes differential functional responses after CNP and BNP stimulation in failing myocardium.
  • Qvigstad, Eirik; Afzal, Faraz; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar & Skomedal, Tor [Show all 8 contributors for this article] (2010). The NO/cyclic GMP signalling pathway differentially affects 5-HT4 - and B1-AR mediated inotropic responses in failing ventricle.
  • Meier, Silja; Aronsen, Jan Magnus; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn & Qvigstad, Eirik (2010). C-type natriuretic peptide signalling through NPR-B enhances the B1-AR signalling both in non-failing and failing rat hearts.
  • Klemp, Marianne; Tvete, Ingunn Fride; Skomedal, Tor; Gaasemyr, Jørund; Natvig, Bent & Aursnes, Ivar Andreas (2009). BAYESIAN STATISTICAL APPROACH FOR COMPARING THE CLINICAL EFFICACY OF THE PARTIAL DOPAMINERGIC AGONIST ARIPIPRAZOLE TO OTHER ANTIPSYCHOTICS.
  • Afzal, Faraz; Aronsen, Jon magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Levy, Finn Olav & Skomedal, Tor [Show all 8 contributors for this article] (2009). Differential regulation of b2-adrenoceptor-mediated responses by PDE3 and PDE4 in failing and non-failing rat myocardium.
  • Krobert, Kurt Allen; Hussain, Rizwan; Afzal, Faraz; Aronsen, Jon magnus; Sjaastad, Ivar & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2009). Inreased Gi activity does not contribute to the reduced beta-adrenergic inotropic effect in failing rat ventricle but Gi acts as a tonic brake on basal adenylyl cyclase activity.
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Sagave, Julia Fritzi; Krobert, Kurt Allen & Edvardsen, Thor [Show all 10 contributors for this article] (2009). CCN2/CTGF - Connective Tissue Growth Factor - Reduces beta-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5. Circulation. ISSN 0009-7322. 120(18), p. S720–S720.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Nguyen, Hong Cam Thi; Sjaastad, Ivar; Afzal, Faraz & Skomedal, Tor [Show all 9 contributors for this article] (2008). Phospodiesterases regulating the negative inotropic response of C-type natriuretic peptide in heart failure. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, p. 17–17.
  • Eikemo, Hilde; Nguyen, Hong Cam Thi; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn (2008). Evidence for an unidentified kinase activity phosphorylating myosin light chain-2 in quiescent cardiomyocytes. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 44, p. 782–782. doi: 10.1016/j.yjmcc.2008.02.170.
  • Kjekshus, John; Edvardsen, Thor; Gullestad, Lars; Koeber, L; Osnes, Jan-Bjørn & Qvigstad, Erik [Show all 10 contributors for this article] (2008). The effect of Piboserod a 5-HT4-receptor antagonist on left ventricular function in patients with symptomatic heart failure.
  • Gravning, Jørgen Amundsen; Ahmed, Muhammad Shakil; Qvigstad, Erik; Sagave, Julia Fritzi; Krobert, Kurt Allen & Edvardsen, Thor [Show all 10 contributors for this article] (2008). Connective tissue growth factor (CTGF/CCN2) desensitizes myocardial beta-adrenergic receptor signaling and inhibits isoproterenol induced hypertrophy.
  • Afzal, Faraz; Andressen, Kjetil Wessel; Mørk, Halvor Kjeang; Aronsen, Jon magnus; Moltzau, Lise Roman & Sjaastad, Ivar [Show all 10 contributors for this article] (2007). 5-HT4-mediated positive inotropic effect is regulated by phosphodiesterase 3 in failing rat heart and human ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 42(6), p. S152–S152.
  • Krobert, Kurt Allen; Hussain, Rizwan; Mørk, Halvor Kjeang; Qvigstad, Eirik; Sjaastad, Ivar & Osnes, Jan-Bjørn [Show all 8 contributors for this article] (2007). cAMP-dependent inotropic effects are differentially regulated by muscarinic inhibition in failing rat ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 42(6), p. S35–S35.
  • Aronsen, Jon magnus; Qvigstad, Eirik; Hougen, Karina; Birkeland, Jon Arne; Levy, Finn Olav & Osnes, Jan-Bjørn [Show all 11 contributors for this article] (2007). Role of alpha-1-adrenergic signallling in Serca2 knockout mice.
  • Brattelid, Trond; Qvigstad, Eirik; Birkeland, Jon Arne; Swift, Fredrik; Bekkevold, SVS & Krobert, Kurt Allen [Show all 11 contributors for this article] (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 40, p. 944–945.
  • Eikemo, Hilde; Qvigstad, Eirik; Krobert, Kurt Allen; Nunn, Caroline; Levy, Finn Olav & Skomedal, Tor [Show all 7 contributors for this article] (2006). Kinetics of myosin light chain phosphorylation in the heart. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 40, p. 994–995.
  • Qvigstad, Eirik; Sjaastad, Ivar; Brattelid, Trond; Nunn, Caroline; Swift, Fredrik & Birkeland, Jon Arne [Show all 12 contributors for this article] (2006). Induction of functional serotonin 5-HT2A and 5-HT4 receptors in the acute failing cardiac ventricle. Journal of Pharmacological Sciences (JPS). ISSN 1347-8613. 101, p. 73–73.
  • Brattelid, Trond; Qvigstad, Eirik; Birkeland, Jon Arne; Swift, Fredrik; Bekkevold, Silje Veslemøy & Krobert, Kurt Allen [Show all 11 contributors for this article] (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Pharmacological Sciences (JPS). ISSN 1347-8613. 101, p. 74–74.
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti & Krobert, Kurt Allen [Show all 11 contributors for this article] (2006). Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart. Journal of Pharmacological Sciences (JPS). ISSN 1347-8613. 101, p. 75–75.
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti & Krobert, Kurt Allen [Show all 11 contributors for this article] (2006). Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 40, p. 943–944.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2016). Nye brukere av benzodiazepiner og Z-hypnotika og uførhet. Norsk Regnesentral.
  • Tvete, Ingunn Fride; Bjørner, Trine & Skomedal, Tor (2015). Benzodiazepinbruk over tid og risiko for doseeskalering: å starte med diazepam versus oxazepam. Norsk Regnesentral.
  • Eikemo, Hilde; Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2009). Regulation of myosin light chain 2 phosphorylation in cardiac muscle and its possible role in contractile responses. Universitetet i Oslo. ISSN 978-82-8072-348-2.
  • Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2009). Regulation of myosin light chain 2 phosphorylation in cardiac muscle and its possible role in contractile responses. Universitetet i Oslo.

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Published Apr. 13, 2011 2:55 PM - Last modified May 27, 2011 4:10 PM