Tom Eirik Mollnes

Adjunct Professor - Department of Immunology
Image of Tom Eirik Mollnes
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Phone +47 22207287
Mobile phone +47 90630015
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postal address OUS HF Rikshospitalet Postboks 4950 Nydalen 0424 Oslo

Publications

  • Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Ekdahl KN, Mollnes TE, Nilsson PH. (2017) Properdin binding to complement activating surfaces depends on initial C3b-deposition. Proc Natl Acad Sci USA. doi: 10.1073/pnas.1612385114
  • Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE. (2017) Dual inhibition of complement and toll-like receptors as a novel approach to treat inflammatory diseases – C3 or C5 emerge together with CD14 as promising targets. J Leukocyte Biol 101:193-204.
  • Nymo S, Gustavsen A, Nilsson PH, Lau C, Espevik T, Mollnes TE. (2016) Human endothelial cell activation by Escherichia coli and Staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. J Immunol 196:2293-2299.
  • Meroni PL, Macor P, Durigutto P, De Maso L, Gerosa M, Ferraresso M, Borghi M, Mollnes TE, Tedesco F. (2016) Complement activation in anti-phospholipid syndrome and its inhibition to prevent re-thrombosis after arterial surgery. Blood 127:365-367.
  • Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing TLR4-MD2. J Infect Dis 214:140-150.
  • Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Crit Care 19:415:1-8.
  • Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE.(2014) Double-blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. J Immunol 192:5324-5331.
  • Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE. (2011) Alginate microbeads are complement-compatible in contrast to polycation containing microcapsules revealed by a human whole blood model. Acta Biomater 7:25678.
  • Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE. (2011) Ornithodoros moubata complement inhibitor (OmCI) is an equally effective C5 inhibitor in pig and human. J Immunol 187:4913-4919.
  • Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE. (2010) CD14-inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli-sepsis in pigs. FASEB J 24:712-722.
  • Husebye H, Hjelmseth M, Stenvik J, Samstad E, Skjeldal F, Halaas Ø, Nilsen, NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T. (2010) The Rab11a GTPase selectively controls Toll-like receptor 4 induced IRF3 activation by regulating trafficking to phagosomes. Immunity 33:583-596.
  • Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE. (2009) Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature. Proc Natl Acad Sci USA 106:15861-15866.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE. (2004) Excersice reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J 25:350-356.
  • Sprong T, Brandtzaeg P, Fung M, Pharo A, Høiby AE, Michaelsen T, Aase A, van der Meer JWM, van Deuren M, Mollnes TE. (2003) Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis. Blood 102:3702-3710.
  • Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR, Fung M, Mollnes TE. (2003) Mechanism of complement activation and its role in the inflammatory response following thoraco-abdominal aortic aneurysm repair. Circulation 108:849-856.
  • Mollnes TE, Brekke OL, Fung M, Fure H, Christiansen D, Bergseth G, Videm V, Lappegård KT, Köhl J, Lambris J. (2002) Essential role of the C5a receptor in E. coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100:1869-1877.
  • Aukrust P, Gullestad L, Lappegård KT, Ueland T, Aass H, Wikeby L, Simonsen S, Frøland SS, Mollnes TE. (2001) Complement activation in patients with congestive heart failure - effect of high-dose intravenous immunoglobulin treatment. Circulation 104:1494-1500.
  • Brandtzaeg P, Høgåsen K, Kierulf P, Mollnes TE. (1996) The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation. J Infect Dis 173:647-655.
  • Askarian, Fatemeh; Uchiyama, Satoshi; Masson, Helen; Sørensen, Henrik Vinther; Golten, Ole; Bunæs, Anne Cathrine; Mekasha, Sophanit; Røhr, Åsmund Kjendseth; Kommedal, Eirik Garpestad; Ludviksen, Judith Anita; Arntzen, Magnus Øverlie; Schmidt, Benjamin; Zurich, Raymond H.; Van Sorge, Nina M.; Eijsink, Vincent; Krengel, Ute; Mollnes, Tom Eirik; Lewis, Nathan E.; Nizet, Victor & Vaaje-Kolstad, Gustav (2021). The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection. Nature Communications.  ISSN 2041-1723. . doi: 10.1038/s41467-021-21473-0 Full text in Research Archive.
  • Debler, Lisa; Palmer, Annette; Braumüller, Sonja; Klohs, Bettina; Mollnes, Tom Eirik; Holzmann, Karlheinz; Huber-Lang, Markus & Halbgebauer, Rebecca (2021). Hemorrhagic shock induces a rapid transcriptomic shift of the immune balance in leukocytes after experimental multiple injury. Mediators of Inflammation.  ISSN 0962-9351.  2021, s 1- 9 . doi: 10.1155/2021/6654318 Full text in Research Archive.
  • Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel & Mollnes, Tom Eirik (2021). Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia.  ISSN 1742-7061.  127, s 169- 179 . doi: 10.1016/j.actbio.2021.03.047
  • Rognes, Ingrid Nygren; Pischke, Søren Erik; Ottestad, William; Røislien, Jo; Berg, Jens Petter; Johnson, Christina; Eken, Torsten & Mollnes, Tom Eirik (2021). Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study. Molecular medicine (Cambridge, Mass. Print).  ISSN 1076-1551.  27(1), s 1- 13 . doi: 10.1186/s10020-021-00286-3
  • Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Huq, Tahmida N.; Nilsson, Per; Mollnes, Tom Eirik; Tran, Khoa D.; Patzer, Corrina; Dohlman, Claes H.; Patra, Hirak K.; Paschalis, Eleftherios I.; Gonzalez-Andrades, Miguel & Chodosh, James (2021). Electron Beam Sterilization of Poly(Methyl Methacrylate)—Physicochemical and Biological Aspects. Macromolecular Bioscience.  ISSN 1616-5187.  21(4) . doi: 10.1002/mabi.202000379
  • Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Koza, Darrell; Reyes-Ortega, Felisa; Alba-Molina, David; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Chodosh, James & Gonzalez-Andrades, Miguel (2021). Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications. Bioactive Materials.  ISSN 2452-199X.  6(11), s 3947- 3961 . doi: 10.1016/j.bioactmat.2021.03.042 Full text in Research Archive.
  • Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias; Thorsvik, Silje; Flatberg, Arnar; Sporsheim, Bjørnar; Ostrop, Jenny; Mollnes, Tom Eirik; Sandvik, Arne Kristian & Bruland, Torunn (2021). Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration. Frontiers in Pharmacology.  ISSN 1663-9812.  12:679741, s 1- 15 . doi: 10.3389/fphar.2021.679741 Full text in Research Archive. Show summary
  • Storm, Benjamin; Halvorsen, Per Steinar; Skulstad, Helge; Dybwik, Knut Gustav; Schjalm, Camilla; Christiansen, Dorte; Wisløff-Aase, Kristin; Fosse, Erik; Braaten, Tonje Bjørndal; Nielsen, Erik Waage & Mollnes, Tom Eirik (2021). Open chest and pericardium facilitate transpulmonary passage of venous air emboli. Acta Anaesthesiologica Scandinavica.  ISSN 0001-5172.  65(5), s 648- 655 . doi: 10.1111/aas.13796
  • Sundnes, Olav; Ottestad, William Arne; Schjalm, Camilla; Lundbäck, Peter; La Cour Poulsen, Lars; Mollnes, Tom Eirik; Haraldsen, Guttorm & Eken, Torsten (2021). Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study. Molecular medicine (Cambridge, Mass. Print).  ISSN 1076-1551.  27 . doi: 10.1186/s10020-021-00288-1 Full text in Research Archive.
  • Thorgersen, Ebbe Billmann; Asvall, Jørund; Frøysnes, Ida Storhaug; Schjalm, Camilla; Larsen, Stein Gunnar; Dueland, Svein; Andersson, Yvonne; Fodstad, Øystein; Mollnes, Tom Eirik & Flatmark, Kjersti (2021). Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. Annals of Surgical Oncology.  ISSN 1068-9265. . doi: 10.1245/s10434-021-10022-0
  • Zhu, Geyunjian Harry; Azharuddin, Mohammad; Islam, Rakibul; Rahmoune, Hassan; Deb, Suryyani; Kanji, Upasona; Das, Jyotirmoy; Osterrieth, Johannes; Aulakh, Parminder; Ibrahim-Hashi, Hashi; Manchanda, Raghav; Nilsson, Per; Mollnes, Tom Eirik; Bhattacharyya, Maitreyee; Islam, Mohammad Mirazul; Hinkula, Jorma; Slater, Nigel K. H. & Patra, Hirak K. (2021). Innate Immune Invisible Ultrasmall Gold Nanoparticles - Framework for Synthesis and Evaluation. ACS Applied Materials & Interfaces.  ISSN 1944-8244. . doi: 10.1021/acsami.1c02834
  • Berg, Leif Kyrre; Goll, Rasmus; Fagerli, Erik; Ludviksen, Judith K; Fure, Hilde; Odd Sverre, Moen; Sørbye, Sveinung; Mollnes, Tom Eirik & Florholmen, Jon (2020). Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  55(5), s 537- 542 . doi: 10.1080/00365521.2020.1754455 Full text in Research Archive.
  • Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta & Pischke, Soeren (2020). Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study. Journal of Neurotrauma.  ISSN 0897-7151.  37(19), s 2120- 2130 . doi: 10.1089/neu.2019.6963 Full text in Research Archive.
  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi; Yin, Hang; Mollnes, Tom Eirik; Damås, Jan Kristian; Espevik, Terje & Stenvik, Jørgen (2020). TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology.  ISSN 0741-5400.  107(4), s 673- 683 . doi: 10.1002/JLB.3A0120-114R Full text in Research Archive.
  • Grinde, Dina Mikhailovna; Øverland, Torstein; Lima, Kari; Schjalm, Camilla; Mollnes, Tom Eirik & Abrahamsen, Tore G (2020). Complement Activation in 22q11.2 Deletion Syndrome. Journal of Clinical Immunology.  ISSN 0271-9142.  40(3), s 515- 523 . doi: 10.1007/s10875-020-00766-x Full text in Research Archive.
  • Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne; Holten, Aleksander Rygh; Tonby, Kristian; Barratt-Due, Andreas; Sokolova, Marina; Schjalm, Camilla; Chaban, Viktoriia; Kolderup, Heidi Anette; Tran, Trung; Tollefsrud Gjølberg, Torleif; Skeie, Linda Gail; Hesstvedt, Liv; Ormaasen, Vidar; Fevang, Børre; Austad, Cathrine; Muller, Karl Erik; Fladeby, Cathrine; Holberg-Petersen, Mona; Halvorsen, Bente; Müller, Fredrik; Aukrust, Pål; Dudman, Susanne Gjeruldsen; Ueland, Thor; Andersen, Jan Terje; Lund-Johansen, Fridtjof; Heggelund, Lars; Dyrhol-Riise, Anne Ma & Mollnes, Tom Eirik (2020). Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  117(40), s 25018- 25025 . doi: 10.1073/pnas.2010540117 Full text in Research Archive.
  • Hovland, Anders; Retterstøl, Kjetil; Mollnes, Tom Eirik; Halvorsen, Bente Evy; Aukrust, Pål & Lappegård, Knut Tore (2020). Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  s 1- 7 . doi: 10.1080/14017431.2020.1775878 Full text in Research Archive.
  • Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik; Schjalm, Camilla; Tonby, Kristian; Pischke, Soeren; Jenum, Synne; Skeie, Linda Gail; Nur, Sarah; Lind, Andreas; Opsand, Hanne; Enersen, Tone Burvald; Grøndahl, Ragnhild; Hermann, Anne; Dudman, Susanne Gjeruldsen; Müller, Fredrik; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars; Holten, Aleksander Rygh & Dyrhol-Riise, Anne Ma (2020). Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19. Scientific Reports.  ISSN 2045-2322.  10 . doi: 10.1038/s41598-020-78710-7 Full text in Research Archive.
  • Keshari, Ravi Shankar; Silasi, Robert; Popescu, Narcis Ioan; Regmi, Girija; Chaaban, Hala; Lambris, John D.; Lupu, Cristina; Mollnes, Tom Eirik & Lupu, Florea (2020). CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  19(2), s 429- 443 . doi: 10.1111/jth.15162 Full text in Research Archive.
  • Lipcsey, Miklos; Tenhunen, Jyrki; Pischke, Soeren; Kuitunen, Anne; Flaatten, Hans; De Geer, Lina; Sjölin, Jan; Frithiof, Robert; Chew, Michelle S.; Bendel, Stepani; Kawati, Rafael; Larsson, Anders; Mollnes, Tom Eirik; Tønnessen, Tor Inge & Rubertsson, Sten (2020). Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study. Shock.  ISSN 1073-2322.  54(2), s 224- 231 . doi: 10.1097/SHK.0000000000001503 Full text in Research Archive.
  • Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin; Otterdal, Kari; Holm, Kristian; Berge, Rolf Kristian; Mollnes, Tom Eirik; Trøseid, Marius; Halvorsen, Bente; Aukrust, Pål; Fevang, Børre & Jørgensen, Silje Fjellgård (2020). Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency. Frontiers in Immunology.  ISSN 1664-3224.  11 . doi: 10.3389/fimmu.2020.574500 Full text in Research Archive.
  • Mollnes, Tom Eirik & Huber-Lang, Markus (2020). Complement in sepsis — when science meets clinics. FEBS Letters.  ISSN 0014-5793.  594(16), s 2621- 2632 . doi: 10.1002/1873-3468.13881 Full text in Research Archive.
  • Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang; Sporsheim, Bjørnar; Ryan, Liv; Kong, Xiang Yi; Dahl, Tuva Børresdatter; Skjelland, Mona; Sørensen, Kirsten; Rokstad, Anne Mari A.; Yndestad, Arne; Latz, Eicke; Gullestad, Lars; Andersen, Geir Øystein; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik; Halvorsen, Bente & Espevik, Terje (2020). Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine.  ISSN 2352-3964.  60:102985, s 1- 13 . doi: 10.1016/j.ebiom.2020.102985 Full text in Research Archive.
  • Pedersen, Henrik; Jensen, Rasmus K.; Jensen, Jens Magnus B.; Fox, Rachel; Pedersen, Dennis V.; Olesen, Heidi G.; Hansen, Annette G.; Christiansen, Dorte; Mazarakis, Sofia M.M.; Lojek, Neal; Hansen, Pernille; Gadeberg, Trine A.F.; Zarantonello, Alessandra; Laursen, Nick S.; Mollnes, Tom Eirik; Johnson, Matthew B.; Stevens, Beth; Thiel, Steffen & Andersen, Gregers R. (2020). A complement C3–Specific nanobody for modulation of the alternative cascade identifies the C-Terminal domain of C3b as functional in C5 convertase activity. Journal of Immunology.  ISSN 0022-1767.  205(8), s 2287- 2300 . doi: 10.4049/jimmunol.2000752
  • Shahini, Negar; Schjalm, Camilla; Nilsson, Per; Holt, Margrethe Flesvig; Øgaard, Jonas; Lien, Egil; Ahmed, Muhammad Shakil; Attramadal, Håvard; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik & Louwe, Maria Cornelia (2020). Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  523(4), s 867- 873 . doi: 10.1016/j.bbrc.2020.01.018 Full text in Research Archive.
  • Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Paschalis, Eleftherios I. & Chodosh, James (2020). Sputter deposition of titanium on poly(Methyl methacrylate) enhances corneal biocompatibility. Translational Vision Science & Technology.  ISSN 2164-2591.  9:41(13), s 1- 14 . doi: 10.1167/TVST.9.13.41 Full text in Research Archive.
  • Storm, Benjamin; Christiansen, Dorte; Mollnes, Tom Eirik & Nielsen, Erik Waage (2020). Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation. JIM - Journal of Immunological Methods.  ISSN 0022-1759.  487:112876, s 1- 5 . doi: 10.1016/j.jim.2020.112876 Full text in Research Archive.
  • Ueland, Nora Lamark; Ludviksen, Judith K; Hellerud, Bernt C; Mollnes, Tom Eirik & Skjeflo, Espen Waage (2020). Choice of immunoassay to evaluate porcine cytokine levels. Veterinary Immunology and Immunopathology.  ISSN 0165-2427.  230:110129, s 1- 5 . doi: 10.1016/j.vetimm.2020.110129 Full text in Research Archive.
  • Ueland, Thor; Heggelund, Lars; Lind, Andreas; Holten, Aleksander Rygh; Tonby, Kristian; Michelsen, Annika; Jenum, Synne; Jørgensen, Marthe Jøntvedt; Barratt-Due, Andreas; Skeie, Linda Gail; Nordøy, Ingvild; Fraz, Mai Sasaki Aanensen; Paulsen, Else Quist; Pischke, Soeren; Johal, Simreen Kaur; Hesstvedt, Liv; Bogen, Mette; Fevang, Børre; Halvorsen, Bente; Müller, Fredrik; Bekken, Gry Kloumann; Mollnes, Tom Eirik; Dudman, Susanne Gjeruldsen; Aukrust, Pål; Dyrhol-Riise, Anne Ma & Holter, Jan Cato (2020). Elevated plasma sTIM-3 levels in patients with severe COVID-19. Journal of Allergy and Clinical Immunology.  ISSN 0091-6749.  147(1), s 92- 98 . doi: 10.1016/j.jaci.2020.09.007 Full text in Research Archive.
  • Zhang, Jie; Song, Lihong; Pedersen, Dennis V.; Li, Anna; Lambris, John D.; Andersen, Gregers Rom; Mollnes, Tom Eirik; Ma, Ying Jie & Garred, Peter (2020). Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement. eLIFE.  ISSN 2050-084X.  9:e60908, s 1- 19 . doi: 10.7554/ELIFE.60908 Full text in Research Archive.
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Walaas, Gunnar Andreas; Mollnes, Tom Eirik; Gustafsson, Björn; Sandvik, Arne Kristian & Bruland, Torunn (2020). Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and colitis.  ISSN 1873-9946.  14(7), s 920- 934 . doi: 10.1093/ecco-jcc/jjaa022 Full text in Research Archive.
  • Brekke, Ole-Lars; Christiansen, Dorte; Kisserli, Aymric; Fure, Hilde; Dahl, Jim André; Donvito, Béatrice; Reveil, Brigitte; Ludviksen, Judith K; Tabary, Thierry; Mollnes, Tom Eirik & Cohen, Jacques H.M. (2019). Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood. Molecular Immunology.  ISSN 0161-5890.  114, s 139- 148 . doi: 10.1016/j.molimm.2019.07.014 Full text in Research Archive.
  • Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria & Grønli, Ole Kristian (2019). Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study. Psychoneuroendocrinology.  ISSN 0306-4530.  108, s 135- 139 . doi: 10.1016/j.psyneuen.2019.06.014 Full text in Research Archive.
  • Dahm, Anders Erik A; Jacobsen, Eva-Marie; Wik, Hilde Skuterud; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Kanse, Sandip & Sandset, Per Morten (2019). Elevated complement C3 and C4 levels are associated with postnatal pregnancy-related venous thrombosis. Thrombosis and Haemostasis.  ISSN 0340-6245.  119(9), s 1481- 1488 . doi: 10.1055/s-0039-1692426 Full text in Research Archive.
  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus & Cavanagh, Jorunn Pauline (2019). The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model. APMIS - Journal of Pathologiy, Microbiology and Immunology.  ISSN 0903-4641.  127(6), s 475- 483 . doi: 10.1111/apm.12946 Full text in Research Archive.
  • Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari (2019). Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology.  ISSN 0022-1767.  203(4), s 853- 863 . doi: 10.4049/jimmunol.1900503 Full text in Research Archive. Show summary
  • Hagve, Martin Iversen; Gjessing, Petter Fosse; Hole, Mikal Jacob; Jansen, Kirsten M; Fuskevåg, Ole Martin; Mollnes, Tom Eirik; Larsen, Terje S & Irtun, Øivind (2019). Perioperative infusion of glucagon-like peptide-1 prevents insulin resistance after surgical trauma in female pigs. Endocrinology.  ISSN 0013-7227.  160(12), s 2892- 2902 . doi: 10.1210/en.2019-00374 Full text in Research Archive.
  • Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Ludviksen, Judith K; Mollnes, Tom Eirik; Lappegård, Knut Tore & Hovland, Anders (2019). Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model. Journal of clinical apheresis.  ISSN 0733-2459. . doi: 10.1002/jca.21765 Full text in Research Archive.
  • Hokstad, Ingrid; Deyab, Gia; Fagerland, Morten; Lyberg, Torstein; Hjeltnes, Gunnbjørg; Førre, Øystein Thorleiv; Agewall, Stefan; Mollnes, Tom Eirik & Hollan, Ivana (2019). Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. PLOS ONE.  ISSN 1932-6203.  14(7), s 1- 16 . doi: 10.1371/journal.pone.0220079 Full text in Research Archive. Show summary
  • Holt, Margrethe Flesvig; Seim, Bjørn Edvard; Øgaard, Jonas; Olsen, Maria Belland; Woldbæk, Per R; Kvitting, John Peder Escobar; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Nilsson, Per; Louwe, Maria Cornelia & Ranheim, Trine (2019). Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: A dysregulation with potential inflammatory effects. Open heart.  ISSN 2053-3624.  6.e001098(2), s 1- 8 . doi: 10.1136/openhrt-2019-001098 Full text in Research Archive.
  • Høiland, Ina Isabella; Liang, Robin Amanda; Brækkan, Sigrid Kufaas; Pettersen, Kristin; Ludviksen, Judith K; Latysheva, Nadezhda; Snir, Omri; Ueland, Thor; Hindberg, Kristian; Mollnes, Tom Eirik & Hansen, John-Bjarne (2019). Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  17(6), s 934- 943 . doi: 10.1111/jth.14438 Full text in Research Archive.
  • Islam, Mohammad Mirazul; Sharifi, Roholah; Mamodaly, Shamina; Islam, Rakibul; Nahra, Daniel; Abusamra, Dina B.; Hui, Pui Chuen; Adibnia, Yashar; Goulamaly, Mehdi; Paschalis, Eleftherios I.; Cruzat, Andrea; Kong, Jing; Nilsson, Per; Argüeso, Pablo; Mollnes, Tom Eirik; Chodosh, James; Dohlman, Claes H. & Gonzalez-Andrades, Miguel (2019). Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts. Acta Biomaterialia.  ISSN 1742-7061.  96, s 1- 15 . doi: 10.1016/j.actbio.2019.07.002 Full text in Research Archive.
  • Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin; Rashidi, Azita; Michelsen, Annika; Lekva, Tove; Halvorsen, Bente; Trøseid, Marius; Mollnes, Tom Eirik; Berge, Rolf Kristian; Yndestad, Arne; Ueland, Thor; Karlsen, Tom Hemming; Aukrust, Pål; Hov, Johannes Espolin Roksund & Fevang, Børre (2019). Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports.  ISSN 2045-2322.  9:167, s 1- 10 . doi: 10.1038/s41598-018-35367-7 Full text in Research Archive.
  • Kozma, Gergely Tibor; Mészáros, Támas; Vashegyi, Ildikó; Fülöp, Tamás Gábor; Örfi, Erik; Dézsi, László; Rosivall, László; Bavli, Yaelle; Urbanics, Rudolf; Mollnes, Tom Eirik; Barenholz, Yechezkel & Szebeni, János (2019). Pseudo-anaphylaxis to polyethylene glycol (PEG)-coated liposomes: Roles of anti-PEG IgM and complement activation in a porcine model of human infusion reactions. ACS Nano.  ISSN 1936-0851.  13(8), s 9315- 9324 . doi: 10.1021/acsnano.9b03942 Full text in Research Archive.
  • Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K; Fure, Hilde; Espevik, Terje; Moen, Anders; Andersen, Jan Terje & Mollnes, Tom Eirik (2019). NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.. mAbs.  ISSN 1942-0862.  12:e1686319(1), s 1- 13 . doi: 10.1080/19420862.2019.1686319 Full text in Research Archive. Show summary
  • Liang, Robin Amanda; Høiland, Ina Isabella; Ueland, Thor; Aukrust, Pål; Snir, Omri; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Garred, Peter; Mollnes, Tom Eirik & Hansen, John-Bjarne (2019). Plasma levels of mannose-binding lectin and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  s 1- 9 . doi: 10.1111/jth.14539 Full text in Research Archive.
  • Macpherson, Magnhild Eide; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Mollnes, Tom Eirik; Berge, Rolf Kristian; Rashidi, Azita; Otterdal, Kari; Gregersen, Ida; Kong, Xiang Yi; Holven, Kirsten Bjørklund; Aukrust, Pål; Fevang, Børre & Jørgensen, Silje Fjellgård (2019). Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency. Scientific Reports.  ISSN 2045-2322.  9:9427, s 1- 10 . doi: 10.1038/s41598-019-45861-1 Full text in Research Archive.
  • Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf & Eken, Torsten (2019). Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome. Critical Care Medicine.  ISSN 0090-3493.  47(8), s e614- e622 . doi: 10.1097/CCM.0000000000003800 Full text in Research Archive.
  • Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar & Nielsen, Erik Waage (2019). Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. PLOS ONE.  ISSN 1932-6203.  14:e0218624(6) . doi: 10.1371/journal.pone.0218624 Full text in Research Archive.
  • Shahini, Negar; Ueland, Thor; Auensen, Andreas; Michelsen, Annika; Ludviksen, Judith K; Hussain, Amjad Iqbal; Pettersen, Kjell; Aakhus, Svend; Espeland, Torvald; Lunde, Ida Gjervold; Kirschfink, Michael; Nilsson, Per; Mollnes, Tom Eirik; Gullestad, Lars; Aukrust, Pål; Yndestad, Arne & Louwe, Maria Cornelia (2019). Increased complement factor B and Bb levels are associated with mortality in patients with severe aortic stenosis. Journal of Immunology.  ISSN 0022-1767.  203(7), s 1973- 1980 . doi: 10.4049/jimmunol.1801244 Full text in Research Archive.
  • Siljan, William Ward; Holter, Jan Cato; Michelsen, Annika; Nymo, Ståle Haugset; Lauritzen, Trine; Oppen, Kjersti; Husebye, Einar; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål & Heggelund, Lars (2019). Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: Results of a 5-year follow-up cohort study. ERS Monograph.  ISSN 2312-508X.  5(1) . doi: 10.1183/23120541.00014-2019 Full text in Research Archive.
  • Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje; Nielsen, Erik Waage & Mollnes, Tom Eirik (2019). Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology.  ISSN 0161-5890.  112, s 131- 139 . doi: 10.1016/j.molimm.2019.03.014 Full text in Research Archive.
  • Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik & Barratt-Due, Andreas (2019). Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology.  ISSN 0022-1767.  203(6), s 1571- 1578 . doi: 10.4049/jimmunol.1900047 Full text in Research Archive.
  • Thorgersen, Ebbe Billmann; Barratt-Due, Andreas; Haugaa, Håkon; Harboe, Morten; Pischke, Søren; Nilsson, Per & Mollnes, Tom Eirik (2019). The role of complement in liver injury, regeneration, and transplantation.. Hepatology.  ISSN 0270-9139.  70(2), s 725- 736 . doi: 10.1002/hep.30508 Full text in Research Archive.
  • Askarian, Fatemeh; Lapek Jr., John D.; Dongre, Mitesh; Tsai, Chih-Ming; Kumaraswamy, Monika; Kousha, Armin; Valderrama, J. Andrés; Ludviksen, Judith K; Cavanagh, Jorunn Pauline; Uchiyama, Satoshi; Mollnes, Tom Eirik; Gonzalez, David J.; Wai, Sun Nyunt; Victor, Nizet & Johannessen, Mona (2018). Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology.  ISSN 1664-302X.  9 . doi: 10.3389/fmicb.2018.00262 Full text in Research Archive.
  • Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo & Grønli, Ole Kristian (2018). Cytokine profiles and diagnoses in elderly, hospitalised psychiatric patients. BMC Psychiatry.  ISSN 1471-244X.  18(315), s 1- 7 . doi: 10.1186/s12888-018-1900-y Full text in Research Archive.
  • Gaarden, Torfinn Lødøen; Engedal, Knut; Saltyte Benth, Jurate; Larsen, Marianne; Lorentzen, Bernhard; Mollnes, Tom Eirik; Bjølseth, Tor Magne & Castellheim, Albert (2018). Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons. BMC Geriatrics.  ISSN 1471-2318.  18(149) . doi: 10.1186/s12877-018-0836-x Full text in Research Archive.
  • Gaya de Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom Eirik; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja & Seelen, Marc A. (2018). Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. Frontiers in Immunology.  ISSN 1664-3224.  9 . doi: 10.3389/fimmu.2018.02664 Full text in Research Archive.
  • Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein & Klepstad, Pål (2018). The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care.  ISSN 1472-684X.  17(110) . doi: 10.1186/s12904-018-0362-9 Full text in Research Archive.
  • Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Bergseth, Grete; Brekke, Ole-Lars; Mollnes, Tom Eirik; Lappegård, Knut Tore & Hovland, Anders (2018). Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) ? an ex vivo study with blood from a C5-deficient individual. APMIS - Journal of Pathologiy, Microbiology and Immunology.  ISSN 0903-4641.  126(4), s 342- 352 . doi: 10.1111/apm.12821 Full text in Research Archive.
  • Hauge, Karoline Kråkmo; Dahle, Gry; Bendz, Bjørn; Halvorsen, Per Steinar; Abdelnoor, Michael; Mollnes, Tom Eirik & Fosse, Erik (2018). Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  52(1), s 43- 50 . doi: 10.1080/14017431.2017.1416157 Full text in Research Archive.
  • Høiland, Ina Isabella; Liang, Robin Amanda; Hindberg, Kristian; Latysheva, Nadezhda; Brekke, Ole-Lars; Mollnes, Tom Eirik & Hansen, John-Bjarne (2018). Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism. Thrombosis Research.  ISSN 0049-3848.  169, s 50- 56 . doi: 10.1016/j.thromres.2018.06.019 Full text in Research Archive.
  • Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål & Damås, Jan Kristian (2018). Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology.  ISSN 0167-5273.  271, s 1- 7 . doi: 10.1016/j.ijcard.2018.04.136 Full text in Research Archive.
  • Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik & Brekke, Ole-Lars (2018). Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.. Clinical and Experimental Immunology.  ISSN 0009-9104. . doi: 10.1111/cei.13240 Full text in Research Archive.
  • Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik; Skjaervold, Nils Kristian & Klepstad, Pål (2018). Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study. JMIR Research Protocols.  ISSN 1929-0748.  7(1) . doi: 10.2196/resprot.8558 Full text in Research Archive.
  • Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Grindheim, Guro; Garred, Peter; Seljeflot, Ingebjørg; Husebye, Trygve Guttorm; Aukrust, Pål; Yndestad, Arne; Andersen, Geir Øystein; Barratt-Due, Andreas & Mollnes, Tom Eirik (2018). Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock. ESC Heart Failure.  ISSN 2055-5822.  5(3), s 292- 301 . doi: 10.1002/ehf2.12266 Full text in Research Archive.
  • Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas & Mollnes, Tom Eirik (2018). IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology.  ISSN 1664-3224.  9 . doi: 10.3389/fimmu.2018.02035 Full text in Research Archive.
  • Orrem, Hilde Lang; Shetelig, Christian; Ueland, Thor; Limalanathan, Shanmuganathan; Nilsson, Per; Husebye, Trygve Guttorm; Aukrust, Pål; Seljeflot, Ingebjørg; HOFFMANN, PAVEL; Eritsland, Jan; Mollnes, Tom Eirik; Andersen, Geir Øystein & Yndestad, Arne (2018). Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction. International Journal of Cardiology.  ISSN 0167-5273.  268, s 187- 192 . doi: 10.1016/j.ijcard.2018.05.032 Full text in Research Archive.
  • Quist-Paulsen, Else; Aukrust, Pål; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ormaasen, Vidar; Stiksrud, Birgitte; Midttun, Øivind; Ueland, Thor; Ueland, Per Magne; Mollnes, Tom Eirik & Dyrhol-Riise, Anne Ma (2018). High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections. Journal of Neuroinflammation.  ISSN 1742-2094.  15(327) . doi: 10.1186/s12974-018-1366-3 Full text in Research Archive.
  • Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset; Husebye, Einar; Ueland, Thor; Skattum, Lillemor; Bosnes, Vidar; Garred, Peter; Frøland, Stig Sophus; Mollnes, Tom Eirik; Aukrust, Pål & Heggelund, Lars (2018). Low levels of immunoglobulins and mannose-binding lectin are not associated with etiology, severity, or outcome in community-acquired pneumonia. Open Forum Infectious Diseases.  ISSN 2328-8957.  5(2) . doi: 10.1093/ofid/ofy002 Full text in Research Archive.
  • Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg; Chandra, Anupam; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders & Eide, Ivar Anders (2018). Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation. Journal of renal nutrition.  ISSN 1051-2276.  28(5), s 333- 339 . doi: 10.1053/j.jrn.2018.02.008 Full text in Research Archive.
  • Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje; Nielsen, Erik Waage; Brekke, Ole-Lars & Mollnes, Tom Eirik (2018). Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  16(5), s 905- 918 . doi: 10.1111/jth.13979 Full text in Research Archive.
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Bruland, Torunn; Mollnes, Tom Eirik & Sandvik, Arne Kristian (2018). C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release. International Journal of Molecular Sciences.  ISSN 1422-0067.  19(10) . doi: 10.3390/ijms19103257 Full text in Research Archive.
  • Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik & Barratt-Due, Andreas (2018). Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology.  ISSN 1661-7800.  113(4), s 322- 330 . doi: 10.1159/000486542 Full text in Research Archive.
  • Wendelbo, Øystein; Opheim, Elin Netland; Hervig, Tor; Lunde, Turid Helen Felli; Bruserud, Øystein; Mollnes, Tom Eirik & Reikvam, Håkon (2018). Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases. Vox Sanguinis.  ISSN 0042-9007.  113, s 657- 668 . doi: 10.1111/vox.12703 Full text in Research Archive.
  • Wolf-Grosse, Susann; Mollnes, Tom Eirik; Ali, Syed; Stenvik, Jørgen & Nilsen, Asbjørn Magne (2018). Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood. Nanomedicine.  ISSN 1743-5889.  13(14), s 1773- 1785 . doi: 10.2217/nnm-2017-0362
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik & Espevik, Terje (2017). Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.. Journal of Immunology.  ISSN 0022-1767.  199(8), s 2910- 2920 . doi: 10.4049/jimmunol.1700302 Full text in Research Archive. Show summary
  • Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje & Mollnes, Tom Eirik (2017). Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.. Journal of Leukocyte Biology.  ISSN 0741-5400.  101(1), s 193- 204 . doi: 10.1189/jlb.3VMR0316-132R Full text in Research Archive.
  • Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Bjerve, Kristian S; Michelsen, Annika; Aukrust, Pål; Schmidt, EB; Christensen, JH & Jenssen, Trond Geir (2017). Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition.  ISSN 1051-2276.  27(3), s 161- 168 . doi: 10.1053/j.jrn.2016.09.008 Show summary
  • Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B. & Garred, Peter (2017). Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-04121-w Full text in Research Archive.
  • Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje; Brekke, Ole-Lars & Rokstad, Anne Mari (2017). Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia.  ISSN 1742-7061.  58, s 158- 167 . doi: 10.1016/j.actbio.2017.05.052 Full text in Research Archive. Show summary
  • Gustavsen, Alice; Skattum, Lillemor; Bergseth, Grete; Lorentzen, Bjørg; Fløisand, Yngvar; Bosnes, Vidar; Mollnes, Tom Eirik & Barratt-Due, Andreas (2017). Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome. Medicine.  ISSN 0025-7974.  96(11) . doi: 10.1097/MD.0000000000006338 Full text in Research Archive.

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  • Storjord, Elin; Hennø, Linda Torrissen; Mollnes, Tom Eirik & Brekke, Ole-Lars (2020). Analyse av cytokiner. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  140(1), s 1- 3 . doi: 10.4045/tidsskr.18.0961
  • van den Heuvel, Lambertus P.; van de Kar, Nicole C.A.J.; Duineveld, Caroline; Sarlea, Andrei; van der Velden, Thea J.A.M.; Liebrand, Wilhelmus T. B.; van Kraaij, Sanne; Schjalm, Camilla; Bouwmeester, Romy; Wetzels, Jack F.M.; Mollnes, Tom Eirik & Volokhina, Elena B. (2020). The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment. Cellular & Molecular Immunology.  ISSN 1672-7681.  17(6), s 653- 655 . doi: 10.1038/s41423-020-0406-y
  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Mollnes, Tom Eirik & Klingenberg, Claus (2019). The method of combined inhibition of CD14 and C5 in Escherichia coli and Streptococcus agalactiae induced inflammation in human cord blood..
  • Cedzyński, Maciej; Thielens, Nicole M.; Mollnes, Tom Eirik & Vorup-Jensen, Thomas (2019). Editorial: The Role of Complement in Health and Disease. Frontiers in Immunology.  ISSN 1664-3224.  10(1869) . doi: 10.3389/fimmu.2019.01869
  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje & Stenvik, Jørgen (2019). Toll-like receptor 8 senses bacteria in human whole blood.
  • Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari A. (2019). Cholesterol crystals induce thromboinflammation.
  • Mollnes, Tom Eirik (2019). Complement C5 conformation is critical for thrombin-mediated cleavage revealed by a novel human whole blood model.
  • Sokolova, Marina; Ekholt, Karin; Mollnes, Tom Eirik & Pischke, Søren (2019). HYPOXIA FOLLOWED BY WHOLE BLOOD REOXYGENATIONINDUCED ENDOTHELIAL CELL ACTIVATION IN A COMPLEMENTC5 AND TOLL-LIKE RECEPTOR CD14 DEPENDENT MANNER.
  • Storm, Benjamin; Christiansen, Dorte; Fure, Hilde; Nielsen, Erik Waage & Mollnes, Tom Eirik (2019). Air bubbles induce a complement-dependent cytokine release in human whole blood in vitro and venous air embolism leads to an inflammatory response in pigs in vivo.. Molecular Immunology.  ISSN 0161-5890.  114, s 441
  • Ehrnström, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Afset, Jan Egil; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje & Stenvik, Jørgen (2018). Toll-like Receptor 8 is a Major Bacterial Sensor in Human Monocytes and Blood.
  • Nielsen, Erik Waage; Storm, Benjamin; Christiansen, Dorte & Mollnes, Tom Eirik (2018). Venous air embolism-indiced coagulation prevented by complement C5 inhibition. Molecular Immunology.  ISSN 0161-5890.  102, s 192- 193
  • Rokstad, Anne Mari; Gravastrand, Caroline S.; Halvorsen, Bente; Steinkjer, Bjørg; Skjelland, Mona; Jacobsen, Eva Astrid; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars & Espevik, Terje (2018). Cholesterol crystals induce coagulation that can be prevented by targeting complement.
  • Skovdahl, Helene Kolstad; Bruland, Torunn; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Mollnes, Tom Eirik & Sandvik, Arne Kristian (2018). P093 CCL20 and CCR6 on peripheral blood mononuclear cells (PBMC) in inflammatory bowel disease (IBD): a more potent chemokine in ulcerative colitis.
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Doseth, Berit; Sandvik, Arne Kristian & Mollnes, Tom Eirik (2018). CCL20 and CCR6 in peripheral blood mononuclear cells (PBMCs) in Inflammatory Bowel Disease (IBD): A more potent chemokine in Ulcerative Colitis.
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn; Sandvik, Arne Kristian & Bruland, Torunn (2018). Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology.  ISSN 0016-5085.  154(6), s S-1010 . doi: https://doi.org/10.1016/S0016-5085(18)33379-1 Show summary
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik & Espevik, Terje (2017). Cyclodextrin inhibits CC-induced complement activation.
  • Espevik, Terje; Niyonzima, Nathalie; Bakke, Siril Skaret; Halvorsen, Bente; Gregersen, Ida; Skjelland, Mona; Yndestad, Arne; Sandanger, Øystein; Andersen, Geir Øystein; Gullestad, Lars; Latz, Eicke; Aukrust, Pål & Mollnes, Tom Eirik (2017). Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis.
  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Klingenberg, Claus Andreas; Moser, Claus; Esaiassen, Eirin; Cavanagh, Jorunn Pauline; Christophersen, Lars; Mollnes, Tom Eirik; østrup jensen, peter & Flægstad, Trond (2017). The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model.

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Published Apr. 13, 2011 2:55 PM - Last modified Jan. 29, 2020 11:09 AM

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