Tom Eirik Mollnes

Professor II - Department of Immunology
Image of Tom Eirik Mollnes
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Phone +47 22207287
Mobile phone +47 90630015
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Ekdahl KN, Mollnes TE, Nilsson PH. (2017) Properdin binding to complement activating surfaces depends on initial C3b-deposition. Proc Natl Acad Sci USA. doi: 10.1073/pnas.1612385114
  • Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE. (2017) Dual inhibition of complement and toll-like receptors as a novel approach to treat inflammatory diseases – C3 or C5 emerge together with CD14 as promising targets. J Leukocyte Biol 101:193-204.
  • Nymo S, Gustavsen A, Nilsson PH, Lau C, Espevik T, Mollnes TE. (2016) Human endothelial cell activation by Escherichia coli and Staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. J Immunol 196:2293-2299.
  • Meroni PL, Macor P, Durigutto P, De Maso L, Gerosa M, Ferraresso M, Borghi M, Mollnes TE, Tedesco F. (2016) Complement activation in anti-phospholipid syndrome and its inhibition to prevent re-thrombosis after arterial surgery. Blood 127:365-367.
  • Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing TLR4-MD2. J Infect Dis 214:140-150.
  • Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Crit Care 19:415:1-8.
  • Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE.(2014) Double-blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. J Immunol 192:5324-5331.
  • Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE. (2011) Alginate microbeads are complement-compatible in contrast to polycation containing microcapsules revealed by a human whole blood model. Acta Biomater 7:25678.
  • Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE. (2011) Ornithodoros moubata complement inhibitor (OmCI) is an equally effective C5 inhibitor in pig and human. J Immunol 187:4913-4919.
  • Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE. (2010) CD14-inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli-sepsis in pigs. FASEB J 24:712-722.
  • Husebye H, Hjelmseth M, Stenvik J, Samstad E, Skjeldal F, Halaas Ø, Nilsen, NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T. (2010) The Rab11a GTPase selectively controls Toll-like receptor 4 induced IRF3 activation by regulating trafficking to phagosomes. Immunity 33:583-596.
  • Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE. (2009) Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature. Proc Natl Acad Sci USA 106:15861-15866.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland SS, Aukrust P, Mollnes, T.E. (2005) Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischemia and rejection after human heart transplantation. Eur Heart J 26:1660-1665.
  • Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE. (2004) Excersice reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J 25:350-356.
  • Sprong T, Brandtzaeg P, Fung M, Pharo A, Høiby AE, Michaelsen T, Aase A, van der Meer JWM, van Deuren M, Mollnes TE. (2003) Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis. Blood 102:3702-3710.
  • Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR, Fung M, Mollnes TE. (2003) Mechanism of complement activation and its role in the inflammatory response following thoraco-abdominal aortic aneurysm repair. Circulation 108:849-856.
  • Mollnes TE, Brekke OL, Fung M, Fure H, Christiansen D, Bergseth G, Videm V, Lappegård KT, Köhl J, Lambris J. (2002) Essential role of the C5a receptor in E. coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100:1869-1877.
  • Aukrust P, Gullestad L, Lappegård KT, Ueland T, Aass H, Wikeby L, Simonsen S, Frøland SS, Mollnes TE. (2001) Complement activation in patients with congestive heart failure - effect of high-dose intravenous immunoglobulin treatment. Circulation 104:1494-1500.
  • Brandtzaeg P, Høgåsen K, Kierulf P, Mollnes TE. (1996) The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation. J Infect Dis 173:647-655.
  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi; Yin, Hang; Mollnes, Tom Eirik; Damås, Jan Kristian; Espevik, Terje & Stenvik, Jørgen (2020). TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology.  ISSN 0741-5400.  107(4), s 673- 683 . doi: 10.1002/JLB.3A0120-114R Full text in Research Archive.
  • Brekke, Ole-Lars; Christiansen, Dorte; Kisserli, Aymric; Fure, Hilde; Dahl, Jim André; Donvito, Béatrice; Reveil, Brigitte; Ludviksen, Judith K; Tabary, Thierry; Mollnes, Tom Eirik & Cohen, Jacques H.M. (2019). Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood. Molecular Immunology.  ISSN 0161-5890.  114, s 139- 148 . doi: 10.1016/j.molimm.2019.07.014 Full text in Research Archive.
  • Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria & Grønli, Ole Kristian (2019). Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study. Psychoneuroendocrinology.  ISSN 0306-4530.  108, s 135- 139 . doi: 10.1016/j.psyneuen.2019.06.014 Full text in Research Archive.
  • Dahm, Anders Erik A; Jacobsen, Eva-Marie; Wik, Hilde Skuterud; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Kanse, Sandip & Sandset, Per Morten (2019). Elevated complement C3 and C4 levels are associated with postnatal pregnancy-related venous thrombosis. Thrombosis and Haemostasis.  ISSN 0340-6245.  119(9), s 1481- 1488 . doi: 10.1055/s-0039-1692426 Full text in Research Archive.
  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus & Cavanagh, Jorunn Pauline (2019). The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS).  ISSN 0903-4641.  127(6), s 475- 483 . doi: 10.1111/apm.12946 Full text in Research Archive.
  • Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari (2019). Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology.  ISSN 0022-1767.  203(4), s 853- 863 . doi: 10.4049/jimmunol.1900503 Full text in Research Archive. Show summary
  • Hagve, Martin Iversen; Gjessing, Petter Fosse; Hole, Mikal Jacob; Jansen, Kirsten M; Fuskevåg, Ole Martin; Mollnes, Tom Eirik; Larsen, Terje S & Irtun, Øivind (2019). Perioperative infusion of glucagon-like peptide-1 prevents insulin resistance after surgical trauma in female pigs. Endocrinology.  ISSN 0013-7227.  160(12), s 2892- 2902 . doi: 10.1210/en.2019-00374 Full text in Research Archive.
  • Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Ludviksen, Judith K; Mollnes, Tom Eirik; Lappegård, Knut Tore & Hovland, Anders (2019). Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model. Journal of clinical apheresis.  ISSN 0733-2459. . doi: 10.1002/jca.21765 Full text in Research Archive.
  • Hokstad, Ingrid; Deyab, Gia; Fagerland, Morten; Lyberg, Torstein; Hjeltnes, Gunnbjørg; Førre, Øystein Thorleiv; Agewall, Stefan; Mollnes, Tom Eirik & Hollan, Ivana (2019). Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. PLOS ONE.  ISSN 1932-6203.  14(7), s 1- 16 . doi: 10.1371/journal.pone.0220079 Full text in Research Archive. Show summary
  • Holt, Margrethe Flesvig; Seim, Bjørn Edvard; Øgaard, Jonas; Olsen, Maria Belland; Woldbæk, Per R; Kvitting, John Peder Escobar; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Nilsson, Per; Louwe, Maria Cornelia & Ranheim, Trine (2019). Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: A dysregulation with potential inflammatory effects. Open heart.  ISSN 2053-3624.  6.e001098(2), s 1- 8 . doi: 10.1136/openhrt-2019-001098 Full text in Research Archive.
  • Høiland, Ina Isabella; Liang, Robin Amanda; Brækkan, Sigrid Kufaas; Pettersen, Kristin; Ludviksen, Judith K; Latysheva, Nadezhda; Snir, Omri; Ueland, Thor; Hindberg, Kristian; Mollnes, Tom Eirik & Hansen, John-Bjarne (2019). Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  17(6), s 934- 943 . doi: 10.1111/jth.14438 Full text in Research Archive.
  • Islam, Mohammad Mirazul; Sharifi, Roholah; Mamodaly, Shamina; Islam, Rakibul; Nahra, Daniel; Abusamra, Dina B.; Hui, Pui Chuen; Adibnia, Yashar; Goulamaly, Mehdi; Paschalis, Eleftherios I.; Cruzat, Andrea; Kong, Jing; Nilsson, Per; Argüeso, Pablo; Mollnes, Tom Eirik; Chodosh, James; Dohlman, Claes H. & Gonzalez-Andrades, Miguel (2019). Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts. Acta Biomaterialia.  ISSN 1742-7061.  96, s 1- 15 . doi: 10.1016/j.actbio.2019.07.002 Full text in Research Archive.
  • Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin; Rashidi, Azita; Michelsen, Annika; Lekva, Tove; Halvorsen, Bente; Trøseid, Marius; Mollnes, Tom Eirik; Berge, Rolf Kristian; Yndestad, Arne; Ueland, Thor; Karlsen, Tom Hemming; Aukrust, Pål; Hov, Johannes Espolin Roksund & Fevang, Børre (2019). Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports.  ISSN 2045-2322.  9:167, s 1- 10 . doi: 10.1038/s41598-018-35367-7 Full text in Research Archive.
  • Kozma, Gergely Tibor; Mészáros, Támas; Vashegyi, Ildikó; Fülöp, Tamás Gábor; Örfi, Erik; Dézsi, László; Rosivall, László; Bavli, Yaelle; Urbanics, Rudolf; Mollnes, Tom Eirik; Barenholz, Yechezkel & Szebeni, János (2019). Pseudo-anaphylaxis to polyethylene glycol (PEG)-coated liposomes: Roles of anti-PEG IgM and complement activation in a porcine model of human infusion reactions. ACS Nano.  ISSN 1936-0851.  13(8), s 9315- 9324 . doi: 10.1021/acsnano.9b03942 Full text in Research Archive.
  • Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K; Fure, Hilde; Espevik, Terje; Moen, Anders; Andersen, Jan Terje & Mollnes, Tom Eirik (2019). NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.. mAbs.  ISSN 1942-0862.  12(1) . doi: 10.1080/19420862.2019.1686319 Full text in Research Archive. Show summary
  • Liang, Robin Amanda; Høiland, Ina Isabella; Ueland, Thor; Aukrust, Pål; Snir, Omri; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Garred, Peter; Mollnes, Tom Eirik & Hansen, John-Bjarne (2019). Plasma levels of mannose-binding lectin and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  s 1- 9 . doi: 10.1111/jth.14539 Full text in Research Archive.
  • Macpherson, Magnhild Eide; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Mollnes, Tom Eirik; Berge, Rolf Kristian; Rashidi, Azita; Otterdal, Kari; Gregersen, Ida; Kong, Xiang Yi; Holven, Kirsten Bjørklund; Aukrust, Pål; Fevang, Børre & Jørgensen, Silje Fjellgård (2019). Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency. Scientific Reports.  ISSN 2045-2322.  9:9427, s 1- 10 . doi: 10.1038/s41598-019-45861-1 Full text in Research Archive.
  • Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf & Eken, Torsten (2019). Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome. Critical Care Medicine.  ISSN 0090-3493.  47(8), s e614- e622 . doi: 10.1097/CCM.0000000000003800 Full text in Research Archive.
  • Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar & Nielsen, Erik Waage (2019). Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. PLOS ONE.  ISSN 1932-6203.  14:e0218624(6) . doi: 10.1371/journal.pone.0218624 Full text in Research Archive.
  • Shahini, Negar; Ueland, Thor; Auensen, Andreas; Michelsen, Annika; Ludviksen, Judith K; Hussain, Amjad Iqbal; Pettersen, Kjell; Aakhus, Svend; Espeland, Torvald; Lunde, Ida Gjervold; Kirschfink, Michael; Nilsson, Per; Mollnes, Tom Eirik; Gullestad, Lars; Aukrust, Pål; Yndestad, Arne & Louwe, Maria Cornelia (2019). Increased complement factor B and Bb levels are associated with mortality in patients with severe aortic stenosis. Journal of Immunology.  ISSN 0022-1767.  203(7), s 1973- 1980 . doi: 10.4049/jimmunol.1801244 Full text in Research Archive.
  • Siljan, William Ward; Holter, Jan Cato; Michelsen, Annika; Nymo, Ståle Haugset; Lauritzen, Trine; Oppen, Kjersti; Husebye, Einar; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål & Heggelund, Lars (2019). Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: Results of a 5-year follow-up cohort study. ERS Monograph.  ISSN 2312-508X.  5(1) . doi: 10.1183/23120541.00014-2019 Full text in Research Archive.
  • Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje; Nielsen, Erik Waage & Mollnes, Tom Eirik (2019). Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology.  ISSN 0161-5890.  112, s 131- 139 . doi: 10.1016/j.molimm.2019.03.014 Full text in Research Archive.
  • Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik & Barratt-Due, Andreas (2019). Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology.  ISSN 0022-1767.  203(6), s 1571- 1578 . doi: 10.4049/jimmunol.1900047 Full text in Research Archive.
  • Thorgersen, Ebbe Billmann; Barratt-Due, Andreas; Haugaa, Håkon; Harboe, Morten; Pischke, Søren; Nilsson, Per & Mollnes, Tom Eirik (2019). The role of complement in liver injury, regeneration, and transplantation.. Hepatology.  ISSN 0270-9139.  70(2), s 725- 736 . doi: 10.1002/hep.30508
  • Askarian, Fatemeh; Lapek Jr., John D.; Dongre, Mitesh; Tsai, Chih-Ming; Kumaraswamy, Monika; Kousha, Armin; Valderrama, J. Andrés; Ludviksen, Judith K; Cavanagh, Jorunn Pauline; Uchiyama, Satoshi; Mollnes, Tom Eirik; Gonzalez, David J.; Wai, Sun Nyunt; Victor, Nizet & Johannessen, Mona (2018). Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology.  ISSN 1664-302X.  9 . doi: 10.3389/fmicb.2018.00262 Full text in Research Archive.
  • Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo & Grønli, Ole Kristian (2018). Cytokine profiles and diagnoses in elderly, hospitalised psychiatric patients. BMC Psychiatry.  ISSN 1471-244X.  18(315), s 1- 7 . doi: 10.1186/s12888-018-1900-y Full text in Research Archive.
  • Gaarden, Torfinn Lødøen; Engedal, Knut; Saltyte Benth, Jurate; Larsen, Marianne; Lorentzen, Bernhard; Mollnes, Tom Eirik; Bjølseth, Tor Magne & Castellheim, Albert (2018). Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons. BMC Geriatrics.  ISSN 1471-2318.  18(149) . doi: 10.1186/s12877-018-0836-x Full text in Research Archive.
  • Gaya de Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom Eirik; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja & Seelen, Marc A. (2018). Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. Frontiers in Immunology.  ISSN 1664-3224.  9 . doi: 10.3389/fimmu.2018.02664 Full text in Research Archive.
  • Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein & Klepstad, Pål (2018). The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care.  ISSN 1472-684X.  17(110) . doi: 10.1186/s12904-018-0362-9 Full text in Research Archive.
  • Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Bergseth, Grete; Brekke, Ole-Lars; Mollnes, Tom Eirik; Lappegård, Knut Tore & Hovland, Anders (2018). Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) ? an ex vivo study with blood from a C5-deficient individual. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS).  ISSN 0903-4641.  126(4), s 342- 352 . doi: 10.1111/apm.12821 Full text in Research Archive.
  • Hauge, Karoline Kråkmo; Dahle, Gry; Bendz, Bjørn; Halvorsen, Per Steinar; Abdelnoor, Michael; Mollnes, Tom Eirik & Fosse, Erik (2018). Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  52(1), s 43- 50 . doi: 10.1080/14017431.2017.1416157 Full text in Research Archive.
  • Høiland, Ina Isabella; Liang, Robin Amanda; Hindberg, Kristian; Latysheva, Nadezhda; Brekke, Ole-Lars; Mollnes, Tom Eirik & Hansen, John-Bjarne (2018). Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism. Thrombosis Research.  ISSN 0049-3848.  169, s 50- 56 . doi: 10.1016/j.thromres.2018.06.019 Full text in Research Archive.
  • Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål & Damås, Jan Kristian (2018). Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology.  ISSN 0167-5273.  271, s 1- 7 . doi: 10.1016/j.ijcard.2018.04.136 Full text in Research Archive.
  • Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik & Brekke, Ole-Lars (2018). Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.. Clinical and Experimental Immunology.  ISSN 0009-9104. . doi: 10.1111/cei.13240 Full text in Research Archive.
  • Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik; Skjaervold, Nils Kristian & Klepstad, Pål (2018). Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study. JMIR Research Protocols.  ISSN 1929-0748.  7(1) . doi: 10.2196/resprot.8558 Full text in Research Archive.
  • Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Grindheim, Guro; Garred, Peter; Seljeflot, Ingebjørg; Husebye, Trygve Guttorm; Aukrust, Pål; Yndestad, Arne; Andersen, Geir Øystein; Barratt-Due, Andreas & Mollnes, Tom Eirik (2018). Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock. ESC Heart Failure.  ISSN 2055-5822.  5(3), s 292- 301 . doi: 10.1002/ehf2.12266 Full text in Research Archive.
  • Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas & Mollnes, Tom Eirik (2018). IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology.  ISSN 1664-3224.  9 . doi: 10.3389/fimmu.2018.02035 Full text in Research Archive.
  • Orrem, Hilde Lang; Shetelig, Christian; Ueland, Thor; Limalanathan, Shanmuganathan; Nilsson, Per; Husebye, Trygve Guttorm; Aukrust, Pål; Seljeflot, Ingebjørg; HOFFMANN, PAVEL; Eritsland, Jan; Mollnes, Tom Eirik; Andersen, Geir Øystein & Yndestad, Arne (2018). Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction. International Journal of Cardiology.  ISSN 0167-5273.  268, s 187- 192 . doi: 10.1016/j.ijcard.2018.05.032 Full text in Research Archive.
  • Quist-Paulsen, Else; Aukrust, Pål; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ormaasen, Vidar; Stiksrud, Birgitte; Midttun, Øivind; Ueland, Thor; Ueland, Per Magne; Mollnes, Tom Eirik & Dyrhol-Riise, Anne Ma (2018). High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections. Journal of Neuroinflammation.  ISSN 1742-2094.  15(327) . doi: 10.1186/s12974-018-1366-3 Full text in Research Archive.
  • Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset; Husebye, Einar; Ueland, Thor; Skattum, Lillemor; Bosnes, Vidar; Garred, Peter; Frøland, Stig Sophus; Mollnes, Tom Eirik; Aukrust, Pål & Heggelund, Lars (2018). Low levels of immunoglobulins and mannose-binding lectin are not associated with etiology, severity, or outcome in community-acquired pneumonia. Open Forum Infectious Diseases.  ISSN 2328-8957.  5(2) . doi: 10.1093/ofid/ofy002 Full text in Research Archive.
  • Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg; Chandra, Anupam; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders & Eide, Ivar Anders (2018). Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation. Journal of renal nutrition.  ISSN 1051-2276.  28(5), s 333- 339 . doi: 10.1053/j.jrn.2018.02.008 Full text in Research Archive.
  • Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje; Nielsen, Erik Waage; Brekke, Ole-Lars & Mollnes, Tom Eirik (2018). Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  16(5), s 905- 918 . doi: 10.1111/jth.13979 Full text in Research Archive.
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Bruland, Torunn; Mollnes, Tom Eirik & Sandvik, Arne Kristian (2018). C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release. International Journal of Molecular Sciences.  ISSN 1422-0067.  19(10) . doi: 10.3390/ijms19103257 Full text in Research Archive.
  • Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik & Barratt-Due, Andreas (2018). Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology.  ISSN 1661-7800.  113(4), s 322- 330 . doi: 10.1159/000486542 Full text in Research Archive.
  • Wendelbo, Øystein; Opheim, Elin Netland; Hervig, Tor; Lunde, Turid Helen Felli; Bruserud, Øystein; Mollnes, Tom Eirik & Reikvam, Håkon (2018). Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases. Vox Sanguinis.  ISSN 0042-9007.  113, s 657- 668 . doi: 10.1111/vox.12703 Full text in Research Archive.
  • Wolf-Grosse, Susann; Mollnes, Tom Eirik; Ali, Syed; Stenvik, Jørgen & Nilsen, Asbjørn Magne (2018). Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood. Nanomedicine.  ISSN 1743-5889.  13(14), s 1773- 1785 . doi: 10.2217/nnm-2017-0362
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik & Espevik, Terje (2017). Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.. Journal of Immunology.  ISSN 0022-1767.  199(8), s 2910- 2920 . doi: 10.4049/jimmunol.1700302 Full text in Research Archive. Show summary
  • Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje & Mollnes, Tom Eirik (2017). Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.. Journal of Leukocyte Biology.  ISSN 0741-5400.  101(1), s 193- 204 . doi: 10.1189/jlb.3VMR0316-132R Full text in Research Archive.
  • Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Bjerve, Kristian S; Michelsen, Annika; Aukrust, Pål; Schmidt, EB; Christensen, JH & Jenssen, Trond Geir (2017). Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition.  ISSN 1051-2276.  27(3), s 161- 168 . doi: 10.1053/j.jrn.2016.09.008 Show summary
  • Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B. & Garred, Peter (2017). Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-04121-w Full text in Research Archive.
  • Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje; Brekke, Ole-Lars & Rokstad, Anne Mari (2017). Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia.  ISSN 1742-7061.  58, s 158- 167 . doi: 10.1016/j.actbio.2017.05.052 Full text in Research Archive. Show summary
  • Gustavsen, Alice; Skattum, Lillemor; Bergseth, Grete; Lorentzen, Bjørg; Fløisand, Yngvar; Bosnes, Vidar; Mollnes, Tom Eirik & Barratt-Due, Andreas (2017). Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome. Medicine (Baltimore, Md.).  ISSN 0025-7974.  96(11) . doi: 10.1097/MD.0000000000006338 Full text in Research Archive.
  • Harboe, Morten; Johnson, Christina; Nymo, Stig Haugset; Ekholt, Karin; Schjalm, Camilla; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik & Nilsson, Per (2017). Properdin binding to complement activating surfaces depends on initial C3b deposition. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  114(4), s E534- E539 . doi: 10.1073/pnas.1612385114 Full text in Research Archive.
  • Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage & Mollnes, Tom Eirik (2017). Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care.  ISSN 2052-0492.  5:21, s 1- 9 . doi: 10.1186/s40560-017-0217-0 Full text in Research Archive.
  • Hennø, Linda Torrissen; Storjord, Elin; Christiansen, Dorte; Bergseth, Grete; Ludviksen, Judith K; Fure, Hilde; Barene, Svein; Nielsen, Erik Waage; Mollnes, Tom Eirik & Brekke, Ole Lars (2017). Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines ? Consequences for defining reference values in healthy humans. Cytokine.  ISSN 1043-4666.  97, s 86- 95 . doi: 10.1016/j.cyto.2017.05.014 Full text in Research Archive. Show summary
  • Keshari, Ravi Shankar; Silasi, Robert; Popescu, Narcis Ioan; Patel, Maulin Mukeshchandra; Chaaban, Hala; Lupu, Cristina; Coggeshall, K. Mark; Mollnes, Tom Eirik; Demarco, Steven J. & Lupu, Florea (2017). Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  114(31), s E6390- E6399 . doi: 10.1073/pnas.1706818114 Full text in Research Archive.
  • Nilsson, Per; Thomas, Anub Mathew; Bergseth, Grete; Gustavsen, Alice; Volokhina, Elena B.; van den Heuvel, Lambertus P.; Barratt-Due, Andreas & Mollnes, Tom Eirik (2017). Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses. Molecular Immunology.  ISSN 0161-5890.  89, s 111- 114 . doi: 10.1016/j.molimm.2017.05.021 Full text in Research Archive.
  • Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik & Espevik, Terje (2017). Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology.  ISSN 0161-5890.  84, s 43- 50 . doi: 10.1016/j.molimm.2016.09.019
  • Paunas, Theodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Marti, Hans-Peter; Mollnes, Tom Eirik; Berven, Frode & Vikse, Bjørn Egil (2017). Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy. Clinical Proteomics.  ISSN 1542-6416.  14(30) . doi: 10.1186/s12014-017-9165-x Full text in Research Archive.
  • Pischke, Søren Erik; Gustavsen, Alice; Orrem, Hilde Lang; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas & Mollnes, Tom Eirik (2017). Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function. Basic Research in Cardiology.  ISSN 0300-8428.  112:20(3) . doi: 10.1007/s00395-017-0610-9 Full text in Research Archive.
  • Ricklin, Daniel; Barratt-Due, Andreas & Mollnes, Tom Eirik (2017). Complement in clinical medicine: Clinical trials, case reports and therapy monitoring. Molecular Immunology.  ISSN 0161-5890.  89, s 10- 21 . doi: 10.1016/j.molimm.2017.05.013 Full text in Research Archive.
  • Shahini, Negar; Michelsen, Annika; Nilsson, Per; Ekholt, Karin; Gullestad, Lars; Broch, Kaspar; Dahl, Christen Peder; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Yndestad, Arne & Louwe, Maria Cornelia (2017). The alternative complement pathway is dysregulated in patients with chronic heart failure. Scientific Reports.  ISSN 2045-2322.  7 . doi: 10.1038/srep42532 Full text in Research Archive.
  • Shields, Kelly J.; Mollnes, Tom Eirik; Eidet, Jon Roger; Mikkelsen, Knut; Almdahl, Sven Martin; Bottazzi, Barbara; Lyberg, Torstein; Manzi, Susan; Ahearn, Joseph M & Hollan, Ivana (2017). Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases. PLOS ONE.  ISSN 1932-6203.  12(3) . doi: 10.1371/journal.pone.0174577 Full text in Research Archive.
  • Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset; Husebye, Einar; Ueland, Thor; Aukrust, Pål; Mollnes, Tom Eirik & Heggelund, Lars (2017). Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia. European Journal of Clinical Investigation.  ISSN 0014-2972.  48(1) . doi: 10.1111/eci.12865 Full text in Research Archive.
  • Smedbråten, Julia; Sagedal, Solbjørg; Åsberg, Anders; Hartmann, Anders; Rollag, Halvor; Mjøen, Geir; Fagerland, Morten; Hansen, S. W. K.; Mollnes, Tom Eirik & Thiel, S. (2017). Collectin liver 1 and collectin kidney 1 of the lectin complement pathway are associated with mortality after kidney transplantation. American Journal of Transplantation.  ISSN 1600-6135.  17(1), s 265- 271 . doi: 10.1111/ajt.13933
  • Storjord, Elin; Dahl, Jim André; Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Goldbeck-Wood, Sandy; Karlsen, Bård Ove; Berg, Kristin Sandal; Mollnes, Tom Eirik; Nielsen, Erik Waage & Brekke, Ole Lars (2017). Systemic inflammation in acute intermittent porphyria:a case–control study. Clinical and Experimental Immunology.  ISSN 0009-9104.  187(3), s 466- 479 . doi: 10.1111/cei.12899
  • Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per; Sarode, Apoorva; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik & Moghimi, Seyed Moein (2017). Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes. Nature Nanotechnology.  ISSN 1748-3387.  12(6), s 589- 594 . doi: 10.1038/nnano.2017.47 Full text in Research Archive.
  • Wolf-Grosse, Susann; Rokstad, Anne Mari; Ali, Syed; Lambris, JD; Mollnes, Tom Eirik; Nilsen, Asbjørn Magne & Stenvik, Jørgen (2017). Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model. International Journal of Nanomedicine.  ISSN 1176-9114.  12, s 3927- 3940 . doi: 10.2147/IJN.S136453 Full text in Research Archive.
  • Wyller, Vegard Bruun Bratholm; Nguyen, Chinh Bkrong Thi Thuy; Ludviksen, Judith K & Mollnes, Tom Eirik (2017). Transforming growth factor beta (TGF‑β)in adolescent chronic fatigue syndrome. Journal of Translational Medicine.  ISSN 1479-5876.  15(1) . doi: 10.1186/s12967-017-1350-1 Full text in Research Archive.
  • Aresvik, Dina; Lima, Kari; Øverland, Torstein; Mollnes, Tom Eirik & Abrahamsen, Tore G (2016). Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome. Scandinavian Journal of Immunology.  ISSN 0300-9475.  83(3), s 188- 194 . doi: 10.1111/sji.12406
  • Barratt-Due, Andreas; Fløisand, Yngvar; Lang, Hilde Elisabeth; Kvam, Ann Kristin; Holme, Pål Andre; Bergseth, Grete; Tjønnfjord, Geir Erland & Mollnes, Tom Eirik (2016). Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome.. Rheumatology.  ISSN 1462-0324. . doi: 10.1093/rheumatology/kew040 Full text in Research Archive.
  • Garabet, Lamya Samir Noori; Gilboe, Inge-Margrethe; Mowinckel, Marie-Christine; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Sandset, Per Morten & Jacobsen, Eva-Marie (2016). Antiphospholipid antibodies are associated with low levels of complement C3 and C4 in patients with systemic Lupus Erythematosus. Scandinavian Journal of Immunology.  ISSN 0300-9475.  84(2), s 95- 99 . doi: 10.1111/sji.12445
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje & Mollnes, Tom Eirik (2016). Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases.  ISSN 0022-1899.  214(1), s 140- 150 . doi: 10.1093/infdis/jiw100 Full text in Research Archive. Show summary
  • Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik & Ueland, Thor (2016). Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis. Neuropsychiatric Disease and Treatment.  ISSN 1176-6328.  12, s 817- 822 . doi: 10.2147/NDT.S101925 Full text in Research Archive. Show summary
  • Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin; Nicholls, Ian A; Mollnes, Tom Eirik; Fromell, Karin; Nilsson, Bo & Ekdahl, Kristina Nilsson (2016). Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood. Biomaterials.  ISSN 0142-9612.  77, s 111- 119 . doi: 10.1016/j.biomaterials.2015.10.067

View all works in Cristin

  • Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Mollnes, Tom Eirik & Klingenberg, Claus (2019). The method of combined inhibition of CD14 and C5 in Escherichia coli and Streptococcus agalactiae induced inflammation in human cord blood..
  • Cedzyński, Maciej; Thielens, Nicole M.; Mollnes, Tom Eirik & Vorup-Jensen, Thomas (2019). Editorial: The Role of Complement in Health and Disease. Frontiers in Immunology.  ISSN 1664-3224.  10(1869) . doi: 10.3389/fimmu.2019.01869
  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje & Stenvik, Jørgen (2019). Toll-like receptor 8 senses bacteria in human whole blood.
  • Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari A. (2019). Cholesterol crystals induce thromboinflammation.
  • Lipcsey, Miklos; Tenhunen, J; Pischke, Søren; Kuitunen, Anne; Flaatten, Hans; de Geer, L; Sjölin, J; Frithiof, R; Chew, Michelle S; Bendel, S; Kawati, R; Larsson, A; Mollnes, Tom Eirik; Tønnessen, Tor Inge & Rubertsson, Sten (2019). Endotoxin Removal in Septic Shock with the Alteco LPS Adsorber was Safe But Showed No Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial - the Asset Study. Shock.  ISSN 1073-2322. . doi: 10.1097/SHK.0000000000001503
  • Mollnes, Tom Eirik (2019). Complement C5 conformation is critical for thrombin-mediated cleavage revealed by a novel human whole blood model.
  • Sokolova, Marina; Ekholt, Karin; Mollnes, Tom Eirik & Pischke, Søren (2019). HYPOXIA FOLLOWED BY WHOLE BLOOD REOXYGENATIONINDUCED ENDOTHELIAL CELL ACTIVATION IN A COMPLEMENTC5 AND TOLL-LIKE RECEPTOR CD14 DEPENDENT MANNER.
  • Storm, Benjamin; Christiansen, Dorte; Fure, Hilde; Nielsen, Erik Waage & Mollnes, Tom Eirik (2019). Air bubbles induce a complement-dependent cytokine release in human whole blood in vitro and venous air embolism leads to an inflammatory response in pigs in vivo.. Molecular Immunology.  ISSN 0161-5890.  114, s 441
  • Ehrnström, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Afset, Jan Egil; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje & Stenvik, Jørgen (2018). Toll-like Receptor 8 is a Major Bacterial Sensor in Human Monocytes and Blood.
  • Nielsen, Erik Waage; Storm, Benjamin; Christiansen, Dorte & Mollnes, Tom Eirik (2018). Venous air embolism-indiced coagulation prevented by complement C5 inhibition. Molecular Immunology.  ISSN 0161-5890.  102, s 192- 193
  • Rokstad, Anne Mari; Gravastrand, Caroline S.; Halvorsen, Bente; Steinkjer, Bjørg; Skjelland, Mona; Jacobsen, Eva Astrid; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars & Espevik, Terje (2018). Cholesterol crystals induce coagulation that can be prevented by targeting complement.
  • Skovdahl, Helene Kolstad; Bruland, Torunn; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Mollnes, Tom Eirik & Sandvik, Arne Kristian (2018). P093 CCL20 and CCR6 on peripheral blood mononuclear cells (PBMC) in inflammatory bowel disease (IBD): a more potent chemokine in ulcerative colitis.
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Doseth, Berit; Sandvik, Arne Kristian & Mollnes, Tom Eirik (2018). CCL20 and CCR6 in peripheral blood mononuclear cells (PBMCs) in Inflammatory Bowel Disease (IBD): A more potent chemokine in Ulcerative Colitis.
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn; Sandvik, Arne Kristian & Bruland, Torunn (2018). Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology.  ISSN 0016-5085.  154(6), s S-1010 . doi: https://doi.org/10.1016/S0016-5085(18)33379-1 Show summary
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik & Espevik, Terje (2017). Cyclodextrin inhibits CC-induced complement activation.
  • Espevik, Terje; Niyonzima, Nathalie; Bakke, Siril Skaret; Halvorsen, Bente; Gregersen, Ida; Skjelland, Mona; Yndestad, Arne; Sandanger, Øystein; Andersen, Geir Øystein; Gullestad, Lars; Latz, Eicke; Aukrust, Pål & Mollnes, Tom Eirik (2017). Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis.
  • Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Klingenberg, Claus Andreas; Moser, Claus; Esaiassen, Eirin; Cavanagh, Jorunn Pauline; Christophersen, Lars; Mollnes, Tom Eirik; østrup jensen, peter & Flægstad, Trond (2017). The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model.
  • Hansen, John-Bjarne & Mollnes, Tom Eirik (2017, 14. november). Ditt eget immunforsvar kan utløse kronisk sykdom og ta liv. [Internett].
  • Hansen, John-Bjarne & Mollnes, Tom Eirik (2017, 14. november). Ditt eget immunforsvar kan utløse kronisk sykdom og ta liv. [TV].
  • Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegaard, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia & Espevik, Terje (2017). The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes.
  • Storm, Benjamin Stage; Christiansen, Dorte; Dybwik, Knut Gustav; Mollnes, Tom Eirik & Nielsen, Erik Waage (2017). Gas embolism during surgery. A complement mediated condition?.
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Pilely, Katrine; Garred, Peter; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik & Espevik, Terje (2016). β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION.
  • Christiansen, Dorte; Skjeflo, Espen Waage; Landsem, Anne; Dammen Mathisen, Monica; Fure, Hilde; Stenvik, Jørgen; Woodruff, Trent; Espevik, Terje & Mollnes, Tom Eirik (2016). The effect of combined inhibition of C5aR1 and CD14 on phagocytosis of E. coli in human whole blood.
  • Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje & Rokstad, Anne Mari (2016). Cholesterol crystals induce coagulation activation in a complement-dependent manner. Show summary
  • Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje & Rokstad, Anne Mari (2016). Cholesterol crystals induce coagulation activation in a complement-dependent manner. Show summary

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Published Apr. 13, 2011 2:55 PM - Last modified Jan. 29, 2020 11:09 AM

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