Trine Ranheim

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Phone +47 23073358
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Visiting address Sognsvannsveien 20 None 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Holt, Margrethe Flesvig; Seim, Bjørn Edvard; Øgaard, Jonas; Olsen, Maria Belland; Woldbæk, Per R; Kvitting, John Peder Escobar; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Nilsson, Per; Louwe, Maria Cornelia & Ranheim, Trine (2019). Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: A dysregulation with potential inflammatory effects. Open heart.  ISSN 2053-3624.  6.e001098(2), s 1- 8 . doi: 10.1136/openhrt-2019-001098 Full text in Research Archive.
  • Sokolova, Marina; Ranheim, Trine; Louwe, Maria Cornelia; Halvorsen, Bente; Yndestad, Arne & Aukrust, Pål (2019). NLRP3 inflammasome: A novel player in metabolically induced inflammation-potential influence on the myocardium. Journal of Cardiovascular Pharmacology.  ISSN 0160-2446.  74(4), s 276- 284 . doi: 10.1097/FJC.0000000000000704 Full text in Research Archive.
  • Sokolova, Marina; Sjaastad, Ivar; Louwe, Maria Cornelia; Alfsnes, Katrine; Aronsen, Jan Magnus; Zhang, Lili; Haugstad, Solveig Bjærum; Bendiksen, Bård Andre; Øgaard, Jonas; Bliksøen, Marte; Lien, Egil; Berge, Rolf Kristian; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2019). NLRP3 inflammasome promotes myocardial remodeling during diet-induced obesity. Frontiers in Immunology.  ISSN 1664-3224.  10:1621(JULY), s 1- 13 . doi: 10.3389/fimmu.2019.01621 Full text in Research Archive.
  • Torp, May-Kristin; Yang, Kuan; Ranheim, Trine; Lauritzen, Knut Husø; Alfsnes, Katrine; Vinge, Leif Erik; Aukrust, Pål; Stensløkken, Kåre-Olav; Yndestad, Arne & Sandanger, Øystein (2019). Mammalian target of rapamycin (mTOR) and the proteasome attenuates IL-1β expression in primary mouse cardiac fibroblasts. Frontiers in Immunology.  ISSN 1664-3224.  10 . doi: 10.3389/fimmu.2019.01285 Full text in Research Archive.
  • Yang, Kuan; Lauritzen, Knut Husø; Olsen, Maria Belland; Dahl, Tuva Børresdatter; Ranheim, Trine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Aukrust, Pål; Halvorsen, Bente; Nyman, Tuula Anneli; Sandanger, Øystein & Yndestad, Arne (2019). Low cellular NAD+ compromises lipopolysaccharide-induced inflammatory responses via inhibiting TLR4 signal transduction in human monocytes. Journal of Immunology.  ISSN 0022-1767.  203(6), s 1598- 1608 . doi: 10.4049/jimmunol.1801382
  • Ystgaard, Martin Bogale; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar; Ranheim, Trine; Sagen, Ellen Lund; Halvorsen, Bente; Saugstad, Ola Didrik & Yndestad, Arne (2019). Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy. Neonatology.  ISSN 1661-7800.  115(4), s 355- 362 . doi: 10.1159/000497200 Full text in Research Archive. Show summary
  • Sokolova, Marina; Sahraoui, Afaf; Høyem, Merete; Øgaard, Jonas; Lien, Egil; Aukrust, Pål; Yndestad, Arne; Ranheim, Trine & Scholz, Hanne (2018). NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction. American Journal of Physiology. Endocrinology and Metabolism.  ISSN 0193-1849.  315(5), s E912- E923 . doi: 10.1152/ajpendo.00461.2017
  • Abraityte, Judita Aurelija; Vinge, Leif Erik; Askevold, Erik Tandberg; Lekva, Tove; Michelsen, Annika; Ranheim, Trine; Alfsnes, Katrine; Fiane, Arnt E; Aakhus, Svend; Lunde, Ida Gjervold; Dahl, Christen Peder; Aukrust, Pål; Christensen, Geir Arve; Gullestad, Lars; Yndestad, Arne & Ueland, Thor (2017). Wnt5a is elevated in heart failure and affects cardiac fibroblast function. Journal of Molecular Medicine.  ISSN 0946-2716.  95(7), s 767- 777 . doi: 10.1007/s00109-017-1529-1
  • Bermudez, Beatriz; Dahl, Tuva Børresdatter; Medina, Indira; Groeneweg, Mathijs; Holm, Sverre; Montserrat-De La Paz, Sergio; Rousch, Mat; Otten, Jeroen; Hérias, Veronica; Varela, Lourdes M.; Ranheim, Trine; Yndestad, Arne; Ortega-Gomez, Almudena; Abia, Rocio; Nagy, Laszlo; Aukrust, Pål; Muriana, Francisco J.G.; Halvorsen, Bente & Biessen, Erik Anna Leonardus (2017). Leukocyte overexpression of intracellular NAMPT attenuates atherosclerosis by regulating PPARγ-dependent monocyte differentiation and function. Arteriosclerosis, Thrombosis and Vascular Biology.  ISSN 1079-5642.  37(6), s 1157- 1167 . doi: 10.1161/ATVBAHA.116.308187
  • Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil; Attramadal, Håvard; Finsen, Alexandra; Zhang, Lili; Ranheim, Trine; Alfsnes, Katrine; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation.  ISSN 0962-9351.  2017:9450439, s 1- 11 . doi: 10.1155/2017/9450439 Full text in Research Archive.
  • Sokolova, Marina; Vinge, Leif Erik; Alfsnes, Katrine; Olsen, Maria Belland; Eide, Lars; Kaasbøll, Ole Jørgen; Attramadal, Håvard; Torp, May-Kristin; Fosshaug, Linn Elisabeth Lillerud; Rashidi, Azita; Lien, Egil; Finsen, Alexandra; Sandanger, Øystein; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2017). Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids.  ISSN 1388-1981.  1862(2), s 234- 245 . doi: 10.1016/j.bbalip.2016.11.003
  • Sandanger, Øystein; Gao, E; Ranheim, Trine; Bliksøen, Marte; Kaasbøll, Ole Jørgen; Alfsnes, Katrine; Nymo, Ståle Haugset; Rashidi, Azita; Ohm, Ingrid Kristine; Attramadal, Håvard; Aukrust, Pål; Vinge, Leif Erik & Yndestad, Arne (2016). NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  469(4), s 1012- 1020 . doi: 10.1016/j.bbrc.2015.12.051
  • Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine; Krogh-Sørensen, Kristin; Skjelland, Mona; Espevik, Terje; Aukrust, Pål; Lengquist, Mariette; Hedin, Ulf; Jansson, Jan-Håkan; Fransen, Karin; Hansson, Göran K.; Eriksson, Per & Sirsjø, Allan (2016). NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association.  ISSN 2047-9980.  5:e003031(5), s 1- 14 . doi: 10.1161/JAHA.115.003031 Full text in Research Archive.
  • Dhondup, Yangchen; Sjaastad, Ivar; Scott, Helge; Sandanger, Øystein; Zhang, Lili; Haugstad, Solveig Bjærum; Aronsen, Jan Magnus; Ranheim, Trine; Holmen, Sigve; Alfsnes, Katrine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Gullestad, Lars; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2015). Sustained toll-like receptor 9 activation promotes systemic and cardiac inflammation, and aggravates diastolic heart failure in SERCA2a KO Mice. PLOS ONE.  ISSN 1932-6203.  10:e0139715(10) . doi: 10.1371/journal.pone.0139715 Full text in Research Archive.
  • Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309(4), s L378- L387 . doi: 10.1152/ajplung.00342.2014
  • Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasone adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309, s L378- L387 . doi: 10.1152/ajplung.00342.2014
  • Astrup, Elisabeth; Ranheim, Trine; Damås, Jan Kristian; Davi, Giovanni; Santilli, Francesca; Jensenius, Mogens; Vitale, Giustina; Aukrust, Pål; Olano, Juan P & Otterdal, Kari (2014). Increased expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental Rickettsia conorii infection. BMC Infectious Diseases.  ISSN 1471-2334.  14(1) . doi: 10.1186/1471-2334-14-70 Full text in Research Archive.
  • Finsen, Alexandra; Ueland, Thor; Sjaastad, Ivar; Ranheim, Trine; Ahmed, Muhammad Shakil; Dahl, Christen Peder; Askevold, Erik Tandberg; Aakhus, Svend; Husberg, Cathrine; Fiane, Arnt E; Lipp, Martin; Gullestad, Lars; Christensen, Geir Arve; Aukrust, Pål & Yndestad, Arne (2014). The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling. PLOS ONE.  ISSN 1932-6203.  9, s e112172 . doi: 10.1371/journal.pone.0112172
  • Ohm, Ingrid Kristine; Alfsnes, Katrine; Olsen, Maria Belland; Ranheim, Trine; Sandanger, Øystein; Dahl, Tuva Børresdatter; Aukrust, Pål; Finsen, Alexandra; Yndestad, Arne & Vinge, Leif Erik (2014). Toll-like receptor 9 mediated responses in cardiac fibroblasts. PLOS ONE.  ISSN 1932-6203.  9:e0104398(8) . doi: 10.1371/journal.pone.0104398
  • Ohm, Ingrid Kristine; Gao, Erhe; Olsen, Maria Belland; Alfsnes, Katrine; Bliksøen, Marte; Øgaard, Jonas; Ranheim, Trine; Nymo, Ståle Haugset; Holmen, Yangchen Dhondup; Aukrust, Pål; Yndestad, Arne & Vinge, Leif Erik (2014). Toll-like receptor 9-activation during onset of myocardial ischemia does not influence infarct extension. PLOS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0104407
  • Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra; Dahl, Christen Peder; Askevold, Erik Tandberg; Florholmen, Geir; Christensen, Geir Arve; Fitzgerald, Katherine A.; Lien, Egil; Valen, Guro; Espevik, Terje; Aukrust, Pål & Yndestad, Arne (2013). The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR).  ISSN 0008-6363.  99(1), s 164- 174 . doi: 10.1093/cvr/cvt091
  • Askevold, Erik Tandberg; Gullestad, Lars; Aakhus, Svend; Ranheim, Trine; Tønnessen, Theis; Solberg, Ole Geir; Aukrust, Pål & Ueland, Thor (2012). Secreted Wnt Modulators in Symptomatic Aortic Stenosis. Journal of the American Heart Association.  ISSN 2047-9980.  1(6) . doi: 10.1161/JAHA.112.002261
  • Dahl, Tuva Børresdatter; Bermudez, Beatriz; Ranheim, Trine; Otterdal, Kari; Holm, Sverre; Biessen, Erik A; Halvorsen, Bente & Aukrust, Pål (2012). Unraveling the role of nicotinamide phosphoribosyltransferase on lipids in atherosclerosis. Journal of Clinical Lipidology.  ISSN 1933-2874.  7(6), s 697- 707 . doi: 10.2217/CLP.12.71
  • Hol, Johanna; Otterdal, Kari; Breland, Unni Mathilde; Stang, Espen; Pedersen, Turid Margrethe; Hagelsteen, Kathrine; Ranheim, Trine; Kasprzycka, Monika; Halvorsen, Bente; Haraldsen, Guttorm & Aukrust, Pål (2012). Statins Affect the Presentation of Endothelial Chemokines by Targeting to Multivesicular Bodies. PLOS ONE.  ISSN 1932-6203.  7(7) . doi: 10.1371/journal.pone.0040673
  • Smedbakken, Linda Merete; Halvorsen, Bente; Daissormont, Isabelle; Ranheim, Trine; Michelsen, Annika; Skjelland, Mona; Sagen, Ellen Lund; Folkersen, Lasse; Krohg-Sørensen, Kirsten; Russell, David; Holm, Sverre; Ueland, Thor; Fevang, Børre; Hedin, Ulf; Yndestad, Arne; Gullestad, Lars; Hansson, Göran K; Biessen, Erik A & Aukrust, Pål (2012). Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization. Atherosclerosis.  ISSN 0021-9150.  224(1), s 266- 273 . doi: 10.1016/j.atherosclerosis.2012.06.071
  • Yndestad, Arne; Finsen, Alexandra; Ueland, Thor; Husberg, Cathrine; Dahl, Christen Peder; Øie, Erik; Vinge, Leif Erik; Sjaastad, Ivar; Sandanger, Øystein; Ranheim, Trine; Dickstein, Kenneth; Kjekshus, John; Damås, Jan Kristian; Fiane, Arnt E; Hilfiker-Kleiner, Denise; Lipp, Martin; Gullestad, Lars; Christensen, Geir Arve & Aukrust, Pål (2012). The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure. PLOS ONE.  ISSN 1932-6203.  7(3) . doi: 10.1371/journal.pone.0033038
  • Dahl, Tuva Børresdatter; Ranheim, Trine; Holm, Sverre; Berge, Rolf Kristian; Aukrust, Pål & Halvorsen, Bente (2011). Nicotinamide phosphoribosyltransferase and lipid accumulation in macrophages. European Journal of Clinical Investigation.  ISSN 0014-2972.  41(10), s 1098- 1104 . doi: 10.1111/j.1365-2362.2011.02515.x
  • Cameron, Jamie; Ranheim, Trine; Halvorsen, Bente; Kulseth, Mari Ann; Leren, Trond Paul & Berge, Knut Erik (2010). Tangier disease caused by compound heterozygosity for ABCA1 mutations R282X and Y1532C. Atherosclerosis.  ISSN 0021-9150.  209(1), s 163- 166 . doi: 10.1016/j.atherosclerosis.2009.08.039
  • Dahl, Tuva Børresdatter; Haukeland, John Willy; Yndestad, Arne; Ranheim, Trine; Gladhaug, Ivar Prydz; Damås, Jan Kristian; Haaland, Therese Kristina; Løberg, Else Marit; Arntsen, Borghild M; Birkeland, Kåre I.; Bjøro, Kristian; Ulven, Stine Marie; Zbigniew, Konopski; Nebb, Hilde Irene; Aukrust, Pål & Halvorsen, Bente (2010). Intracellular Nicotinamide Phosphoribosyltransferase Protects against Hepatocyte Apoptosis and Is Down-Regulated in Nonalcoholic Fatty Liver Disease. Journal of Clinical Endocrinology and Metabolism.  ISSN 0021-972X.  95(6), s 3039- 3047 . doi: 10.1210/jc.2009-2148
  • Michelsen, Annika; Rathcke, CN; Skjelland, Mona; Holm, Sverre; Ranheim, Trine; Krohg-Sørensen, Kirsten; Klingvall, Marit Fodnes; Brosstad, Frank Roger; Øie, Erik; Vestergaard, H.; Aukrust, Pål & Halvorsen, Bente (2010). Increased YKL-40 expression in patients with carotid atherosclerosis. Atherosclerosis.  ISSN 0021-9150.  211(2), s 589- 595 . doi: 10.1016/j.atherosclerosis.2010.02.035
  • Holla, Øystein Lunde; Kulseth, Mari Ann; Berge, Knut Erik; Leren, Trond Paul & Ranheim, Trine (2009). Nonsense-mediated decay of human LDL receptor mRNA. Scandinavian Journal of Clinical and Laboratory Investigation.  ISSN 0036-5513.  69(3), s 409- 417 . doi: 10.1080/00365510802707163
  • Tveten, Kristian; Ranheim, Trine; Berge, Knut Erik; Leren, Trond Paul & Kulseth, Mari Ann (2009). The effect of bafilomycin A1 and protease inhibitors on the degradation and recycling of a Class 5-mutant LDLR. Acta Biochimica et Biophysica Sinica.  ISSN 0582-9879.  41(3), s 246- 255 . doi: 10.1093/abbs/gmp008
  • Cameron, Jamie; Holla, Øystein Lunde; Berge, Knut Erik; Kulseth, Mari Ann; Ranheim, Trine; Leren, Trond Paul & Lærdahl, Jon Kristen (2008). Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion. The FEBS Journal.  ISSN 1742-464X.  275(16), s 4121- 4133 . doi: 10.1111/j.1742-4658.2008.06553.x
  • Cameron, Jamie; Holla, Øystein Lunde; Lærdahl, Jon Kristen; Kulseth, Mari Ann; Ranheim, Trine; Rognes, Torbjørn; Berge, Knut Erik & Leren, Trond Paul (2008). Characterization of novel mutations in the catalytic domain of the PCSK9 gene. Journal of Internal Medicine.  ISSN 0954-6820.  263(4), s 420- 431 . doi: 10.1111/j.1365-2796.2007.01915.x

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  • Sokolova, Marina; Sjaastad, Ivar; Alfsnes, Katrina; Louwe, Mieke; Aronsen, Jan Magnus; Zhang, Lili; Haugstad, Solveig Bjærum; Bliksøen, Martha; Lien, Egil; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2014). NLRP3 inflammasome promote myocardial remodeling during diet-induced obesity.
  • Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Valen, Guro; Aukrust, Pål & Yndestad, Arne (2013). A role for NLRP3 inflammasome in acute myocardial ischmia-reperfusion injury? Reply. Cardiovascular Research (CVR).  ISSN 0008-6363.  99(1), s 226- 227 . doi: 10.1093/cvr/cvt130
  • Bliksøen, Marte; Mariero, Lars Henrik; Ohm, Ingrid Kristine; Haugen, Fred; Yndestad, Arne; Solheim, Svein; Seljeflot, Ingebjørg; Ranheim, Trine; Andersen, Geir Øystein; Aukrust, Pål; Valen, Guro & Vinge, Leif Erik (2012). Increased circulating mitochondrial DNA after myocardial infarction. International Journal of Cardiology.  ISSN 0167-5273.  158(1), s 132- 134 . doi: 10.1016/j.ijcard.2012.04.047
  • Ranheim, Trine; Flottorp, Signe Agnes; Austvoll-Dahlgren, Astrid Trobe & Johansen, Marit (2010). Effekter av tverrfaglige ambulante tjenester for pasienter med kroniske sykdommer. Rapport fra Kunnskapssenteret. 7/2010.
  • Holte, Hilde H; Ranheim, Trine & Flottorp, Signe Agnes (2009). Effekt av rehabilitering på deltaking sosialt og i samfunnet. Rapport fra Kunnskapssenteret. 27/2009. Full text in Research Archive. Show summary

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Published Feb. 20, 2012 9:00 AM - Last modified May 22, 2014 2:15 PM